Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionT cell receptor binding

DOCK2 HLA-B HLA-C HLA-E

1.15e-05201444GO:0042608
GeneOntologyMolecularFunctionCD8 receptor binding

HLA-B HLA-C HLA-E

2.99e-0591443GO:0042610
GeneOntologyMolecularFunctionTAP complex binding

HLA-B HLA-C HLA-E

2.99e-0591443GO:0062061
GeneOntologyMolecularFunctionTAP1 binding

HLA-B HLA-C HLA-E

4.25e-05101443GO:0046978
GeneOntologyMolecularFunctionTAP2 binding

HLA-B HLA-C HLA-E

4.25e-05101443GO:0046979
GeneOntologyMolecularFunctionTAP binding

HLA-B HLA-C HLA-E

4.25e-05101443GO:0046977
GeneOntologyMolecularFunctionbeta-2-microglobulin binding

HLA-B HLA-C HLA-E

7.70e-05121443GO:0030881
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

HLA-B HLA-C HLA-E

2.32e-04171443GO:0046703
GeneOntologyMolecularFunctionpeptide antigen binding

HLA-B HLA-C HLA-DPB1 HLA-E

4.27e-04491444GO:0042605
GeneOntologyMolecularFunctionMHC protein binding

HLA-B HLA-C HLA-E CYRIB

8.14e-04581444GO:0042287
GeneOntologyBiologicalProcessRab protein signal transduction

RAB4B RAB30 RAB39A RAB39B RAB4A

2.68e-07211425GO:0032482
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent

HLA-B HLA-C HLA-E

1.74e-0581423GO:0002485
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen

HLA-B HLA-C HLA-DPB1 HLA-E PIKFYVE

1.94e-05481425GO:0002478
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

EPHB2 DOCK2 RAPGEF6 RAPGEF4 CHN1 CYRIB CELSR1 RAB4B RAB30 RASGEF1B RAB39A RAB39B RAB4A RASGRP2

2.15e-0553814214GO:0007264
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous antigen

HLA-B HLA-C HLA-DPB1 HLA-E PIKFYVE

4.92e-05581425GO:0019884
GeneOntologyBiologicalProcessantigen processing and presentation

HLA-B HLA-C HLA-DPB1 HLA-E PSMB8 PIKFYVE RAB4A

5.06e-051391427GO:0019882
GeneOntologyBiologicalProcesspositive regulation of defense response to virus by host

APOBEC3G STING1 APOBEC3F EIF2AK4

1.33e-04381424GO:0002230
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

HLA-B HLA-C HLA-E

1.68e-04161423GO:0002486
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen

HLA-B HLA-C HLA-DPB1 HLA-E PIKFYVE

1.80e-04761425GO:0048002
GeneOntologyBiologicalProcesspositive regulation of T cell mediated cytotoxicity

HLA-B HLA-C HLA-E CYRIB

1.97e-04421424GO:0001916
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway

HLA-B HLA-C HLA-E

2.02e-04171423GO:0002484
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib

HLA-B HLA-C HLA-E

2.02e-04171423GO:0002476
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class Ib

HLA-B HLA-C HLA-E

2.42e-04181423GO:0002428
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen via MHC class I

HLA-B HLA-C HLA-E

2.42e-04181423GO:0042590
GeneOntologyBiologicalProcessregulation of blastocyst development

AGBL4 TTLL4

2.80e-0441422GO:0120222
GeneOntologyBiologicalProcessneurotransmitter receptor transport postsynaptic membrane to endosome

MKLN1 RAB4A

2.80e-0441422GO:0098968
GeneOntologyCellularComponentMHC class Ib protein complex

HLA-B HLA-C HLA-E

1.12e-0571453GO:0032398
GeneOntologyCellularComponentphagocytic vesicle membrane

HLA-B HLA-C HLA-E PIKFYVE RAB43 RAB39A

2.44e-05831456GO:0030670
GeneOntologyCellularComponentMHC protein complex

HLA-B HLA-C HLA-DPB1 HLA-E

2.95e-05261454GO:0042611
GeneOntologyCellularComponentMHC class I protein complex

HLA-B HLA-C HLA-E

3.79e-05101453GO:0042612
GeneOntologyCellularComponentinsulin-responsive compartment

PIKFYVE RAB4B RAB4A

5.18e-05111453GO:0032593
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

HLA-B HLA-C HLA-DPB1 HLA-E

9.84e-05351454GO:0098553
GeneOntologyCellularComponentMHC class I peptide loading complex

HLA-B HLA-C HLA-E

1.13e-04141453GO:0042824
GeneOntologyCellularComponentendocytic vesicle membrane

STAB2 HLA-B HLA-C HLA-DPB1 HLA-E PIKFYVE RAB43 RAB39A

1.19e-042121458GO:0030666
GeneOntologyCellularComponentcis-Golgi network membrane

HLA-B HLA-C HLA-E

2.07e-04171453GO:0033106
GeneOntologyCellularComponentlumenal side of membrane

HLA-B HLA-C HLA-DPB1 HLA-E

3.41e-04481454GO:0098576
GeneOntologyCellularComponentendocytic vesicle

RAPGEF6 STAB2 HLA-B HLA-C HLA-DPB1 HLA-E PIKFYVE RAB43 RAB39A RINL

3.56e-0438414510GO:0030139
GeneOntologyCellularComponentapolipoprotein B mRNA editing enzyme complex

APOBEC3G APOBEC3F

4.71e-0451452GO:0030895
GeneOntologyCellularComponentGolgi membrane

HLA-B HLA-C HLA-DPB1 HLA-E STING1 RXYLT1 CHST13 PIKFYVE QSOX1 GALNT17 RAB30 WSCD2 RAB39A IL17RD

5.03e-0472114514GO:0000139
GeneOntologyCellularComponentGolgi medial cisterna

HLA-B HLA-C HLA-E

5.23e-04231453GO:0005797
GeneOntologyCellularComponentphagocytic vesicle

HLA-B HLA-C HLA-E PIKFYVE RAB43 RAB39A

8.04e-041571456GO:0045335
GeneOntologyCellularComponentmRNA editing complex

APOBEC3G APOBEC3F

9.81e-0471452GO:0045293
GeneOntologyCellularComponentER to Golgi transport vesicle membrane

HLA-B HLA-C HLA-DPB1 HLA-E

1.02e-03641454GO:0012507
DomainRAB

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

1.12e-06731387PS51419
DomainMHC_I_a_C

HLA-B HLA-C HLA-E

7.77e-0661383IPR010579
DomainMHC_I_C

HLA-B HLA-C HLA-E

7.77e-0661383PF06623
DomainRasGEFN

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

1.26e-05201384SM00229
DomainRasGEF_N

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

1.55e-05211384PF00618
DomainRas-like_Gua-exchang_fac_N

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

1.88e-05221384IPR000651
DomainRASGEF_NTER

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

1.88e-05221384PS50212
DomainRASGEF_CAT

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

5.87e-05291384PS50009
DomainRasGEF

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

6.74e-05301384PF00617
Domain-

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

6.74e-053013841.10.840.10
DomainRASGEF_cat_dom

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

6.74e-05301384IPR001895
DomainRasGEF

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

6.74e-05301384SM00147
DomainRas_GEF_dom

RAPGEF6 RAPGEF4 RASGEF1B RASGRP2

6.74e-05301384IPR023578
DomainRas

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

6.82e-051361387PF00071
Domain-

RAB25 TDRD9 RNF213 AK8 SAMD9L MDN1 RAB4B RAB30 RAB43 ERCC6L2 WSCD2 RAB39A RAB39B MYO15A RAB4A AQR

1.28e-04746138163.40.50.300
DomainMHC_I/II-like_Ag-recog

HLA-B HLA-C HLA-DPB1 HLA-E

1.73e-04381384IPR011162
DomainP-loop_NTPase

RAB25 TDRD9 RNF213 AK8 SAMD9L SPATA17 MDN1 RAB4B RAB30 RAB43 ERCC6L2 WSCD2 RAB39A RAB39B MYO15A RAB4A AQR

1.75e-0484813817IPR027417
DomainSmall_GTPase

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

1.88e-041601387IPR001806
DomainSmall_GTP-bd_dom

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

2.45e-041671387IPR005225
DomainMHC_I

HLA-B HLA-C HLA-E

4.76e-04211383PF00129
DomainMHC_I_a_a1/a2

HLA-B HLA-C HLA-E

4.76e-04211383IPR001039
DomainGLYCOSYL_HYDROL_F1_1

LCT KLB

5.34e-0451382PS00572
DomainGlyco_hydro_1

LCT KLB

5.34e-0451382PF00232
DomainGLYCOSYL_HYDROL_F1_2

LCT KLB

5.34e-0451382PS00653
DomainGlyco_hydro_1

LCT KLB

5.34e-0451382IPR001360
DomainC1-set

HLA-B HLA-C HLA-DPB1 HLA-E

6.78e-04541384PF07654
Domain-

HLA-B HLA-C HLA-E

7.13e-042413833.30.500.10
DomainMHC_I-like_Ag-recog

HLA-B HLA-C HLA-E

7.13e-04241383IPR011161
DomainIGc1

HLA-B HLA-C HLA-DPB1 HLA-E

7.78e-04561384SM00407
DomainIg/MHC_CS

HLA-B HLA-C HLA-DPB1 HLA-E

8.89e-04581384IPR003006
DomainIg_C1-set

HLA-B HLA-C HLA-DPB1 HLA-E

8.89e-04581384IPR003597
DomainRASGEF

RAPGEF4 RASGEF1B RASGRP2

9.06e-04261383PS00720
DomainIG_MHC

HLA-B HLA-C HLA-DPB1 HLA-E

1.01e-03601384PS00290
DomainEGF_LAM_2

STAB2 LAMC2 CELSR1

1.38e-03301383PS50027
DomainEGF_LAM_1

STAB2 LAMC2 CELSR1

1.38e-03301383PS01248
PathwayREACTOME_RAB_GERANYLGERANYLATION

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

6.15e-07651087M27771
PathwayREACTOME_RAB_GERANYLGERANYLATION

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

6.15e-07651087MM15511
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES

HLA-B HLA-C HLA-E

8.60e-0661083M47468
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES

HLA-B HLA-C HLA-E

1.50e-0571083M47582
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES

HLA-B HLA-C HLA-E

1.50e-0571083M47530
PathwayREACTOME_ENDOSOMAL_VACUOLAR_PATHWAY

HLA-B HLA-C HLA-E

3.55e-0591083MM14527
PathwayREACTOME_ENDOSOMAL_VACUOLAR_PATHWAY

HLA-B HLA-C HLA-E

6.90e-05111083M525
PathwayKEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES

HLA-B HLA-C HLA-E

9.15e-05121083M47529
PathwayKEGG_ALLOGRAFT_REJECTION

HLA-B HLA-C HLA-DPB1 HLA-E

1.77e-04371084M18615
PathwayKEGG_VIRAL_MYOCARDITIS

HLA-B HLA-C HLA-DPB1 HLA-E CCND1

1.96e-04701085M12294
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

HLA-B HLA-C HLA-DPB1 HLA-E

2.65e-04411084M13519
PathwayKEGG_TYPE_I_DIABETES_MELLITUS

HLA-B HLA-C HLA-DPB1 HLA-E

3.19e-04431084M12617
PathwayREACTOME_INTERFERON_ALPHA_BETA_SIGNALING

HLA-B HLA-C HLA-E PSMB8 IFNB1

3.26e-04781085M973
PathwayREACTOME_ER_PHAGOSOME_PATHWAY

HLA-B HLA-C HLA-E

3.28e-04181083MM14525
PathwayREACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES

NUP107 HLA-B HLA-C HLA-E STING1 IFNB1

4.12e-041261086M45009
PathwayBIOCARTA_CTL_PATHWAY

HLA-B HLA-C HLA-E

4.53e-04201083MM1374
Pubmed

Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING.

HLA-B HLA-C HLA-E STING1 IFNB1

4.78e-0916144532723479
Pubmed

Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

2.12e-0872144716923123
Pubmed

HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms.

HLA-B HLA-C HLA-DPB1 HLA-E

3.49e-089144419180512
Pubmed

Nonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum.

HLA-B HLA-C HLA-E CYRIB

9.09e-0811144422522492
Pubmed

Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection.

HLA-B HLA-C APOBEC3G APOBEC3F

9.09e-0811144425827531
Pubmed

Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.

RAB25 RAB4B RAB30 RAB43 RAB39A RAB4A

1.54e-0758144611856727
Pubmed

Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B

2.09e-0761144612578829
Pubmed

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

RAB25 RAB4B RAB30 RAB43 RAB39A RAB4A

2.30e-0762144611773082
Pubmed

Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.

HLA-B HLA-C HLA-E

2.77e-074144325754738
Pubmed

Effects of HLA allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplantation with T-cell-replete marrow from an unrelated donor.

HLA-B HLA-C HLA-DPB1

2.77e-074144317317585
Pubmed

Viral factors in non-progression.

HLA-B HLA-C APOBEC3G

6.91e-075144324400003
Pubmed

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer.

HLA-B HLA-C HLA-E

6.91e-07514439754572
Pubmed

HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.

HLA-B HLA-C HLA-E

6.91e-075144321699788
Pubmed

APOBEC3 inhibits DEAD-END function to regulate microRNA activity.

APOBEC3G DND1 APOBEC3F

6.91e-075144323890083
Pubmed

Allergic and Nonallergic Asthma Have Distinct Phenotypic and Genotypic Features.

HLA-B HLA-C HLA-DPB1

6.91e-075144328380482
Pubmed

Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controls.

HLA-B HLA-C HLA-DPB1

6.91e-075144318486765
Pubmed

HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells.

HLA-B HLA-C HLA-DPB1 HLA-E

1.30e-0620144412427289
Pubmed

Nef performance in macrophages: the master orchestrator of viral persistence and spread.

HLA-B HLA-C HLA-DPB1 HLA-E

1.30e-0620144422103834
Pubmed

gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules.

HLA-B HLA-C HLA-E PTPRO

1.30e-062014449263011
Pubmed

Alteration of the influences of HLA classes I and II alleles on the perinatal hepatitis B virus infection after immunoprophylaxis in Korean children.

HLA-B HLA-C HLA-DPB1

1.38e-066144316890179
Pubmed

Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation.

HLA-B HLA-C HLA-E

1.38e-066144310982373
Pubmed

Multiple receptors converge on H2-Q10 to regulate NK and γδT-cell development.

HLA-B HLA-C HLA-E

1.38e-066144330537346
Pubmed

Characterization of 236 novel alleles at the HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 loci from China Marrow Donor Program.

HLA-B HLA-C HLA-DPB1

1.38e-066144321732917
Pubmed

A nonpolymorphic class I gene in the murine major histocompatibility complex.

HLA-B HLA-C HLA-E

1.38e-06614436420070
Pubmed

High-resolution molecular characterization of the HLA class I and class II in the Tarahumara Amerindian population.

HLA-B HLA-C HLA-DPB1

1.38e-066144316866883
Pubmed

Effect of the V3 loop deletion of envelope glycoprotein on cellular responses and protection against challenge with recombinant vaccinia virus expressing gp160 of primary human immunodeficiency virus type 1 isolates.

HLA-B HLA-C HLA-E

1.38e-066144311932387
Pubmed

Three classes of mouse H-2 messenger RNA distinguished by analysis of cDNA clones.

HLA-B HLA-C HLA-E

1.38e-06614436276751
Pubmed

Transporters associated with antigen processing (TAP)-independent presentation of soluble insulin to alpha/beta T cells by the class Ib gene product, Qa-1(b).

HLA-B HLA-C HLA-E

1.38e-06614439730897
Pubmed

Molecular analysis of presentation by HLA-A2.1 of a promiscuously binding V3 loop peptide from the HIV-envelope protein to human cytotoxic T lymphocytes.

HLA-B HLA-C HLA-E

1.38e-06614438671651
Pubmed

Inhibitor-Immunology-Study. Different HLA-types seem to be involved in the inhibitor development in haemophilia A.

HLA-B HLA-C HLA-DPB1

1.38e-066144318958335
Pubmed

Analysis of HLA class I and class II gene polymorphisms in Japanese patients with human T-cell lymphotropic virus type 1-associated uveitis.

HLA-B HLA-C HLA-DPB1

1.38e-066144316019679
Pubmed

The dileucine-based sorting motif in HIV-1 Nef is not required for down-regulation of class I MHC.

HLA-B HLA-C HLA-E

1.38e-066144310366557
Pubmed

Secretion of a transplantation-related antigen.

HLA-B HLA-C HLA-E

1.38e-06614436411351
Pubmed

The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.

HLA-B HLA-C HLA-E

1.38e-06614439582271
Pubmed

Organization of the AKR Qa region: structure of a divergent class I sequence, Q5k.

HLA-B HLA-C HLA-E

1.38e-06614432639903
Pubmed

Characteristics of the expression of the murine soluble class I molecule (Q10).

HLA-B HLA-C HLA-E

1.38e-06614433940270
Pubmed

The class I-b molecule Qa-1 forms heterodimers with H-2Ld and a novel 50-kD glycoprotein encoded centromeric to I-E beta.

HLA-B HLA-C HLA-E

1.38e-06614437836920
Pubmed

Preferential survival of mice expressing the Qa-2 antigen.

HLA-B HLA-C HLA-E

1.38e-06614438283431
Pubmed

QUOD ERAT FACIENDUM: sequence analysis of the H2-D and H2-Q regions of 129/SvJ mice.

HLA-B HLA-C HLA-E

1.38e-066144312389096
Pubmed

Occurrence of a unique MHC class I gene in distantly related members of the genus Mus.

HLA-B HLA-C HLA-E

1.38e-06614433988322
Pubmed

The degree of matching at HLA-DPB1 predicts for acute graft-versus-host disease and disease relapse following haematopoietic stem cell transplantation.

HLA-B HLA-C HLA-DPB1

1.38e-066144312774051
Pubmed

Correlation of Qa-1 determinants defined by antisera and by cytotoxic T lymphocytes.

HLA-B HLA-C HLA-E

1.38e-06614432580784
Pubmed

Revised nomenclature of mouse H-2 genes.

HLA-B HLA-C HLA-E

1.38e-06614432228044
Pubmed

Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex.

HLA-B HLA-C HLA-E

1.38e-06614436304710
Pubmed

The Qa-1 alloantigens. II. Evidence for the expression of two Qa-1 molecules by the Qa-1d genotype and for cross-reactivity between Qa-1 and H-2K.

HLA-B HLA-C HLA-E

1.38e-06614436822734
Pubmed

Spatial-Temporal Expression of Non-classical MHC Class I Molecules in the C57 Mouse Brain.

HLA-B HLA-C HLA-E

1.38e-066144326040564
Pubmed

Host Expression of the CD8 Treg/NK Cell Restriction Element Qa-1 is Dispensable for Transplant Tolerance.

HLA-B HLA-C HLA-E

1.38e-066144328894277
Pubmed

The Qa-1 alloantigens. III. Biochemical analysis of the structure and extent of polymorphism of the Qa-1 allelic products.

HLA-B HLA-C HLA-E

1.38e-06614433925004
Pubmed

Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen.

HLA-B HLA-C HLA-DPB1

1.38e-066144320073992
Pubmed

Enhanced HIV infectivity and changes in GP120 conformation associated with viral incorporation of human leucocyte antigen class I molecules.

HLA-B HLA-C HLA-E

1.38e-066144310546855
Pubmed

The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation.

HLA-B HLA-C HLA-DPB1

1.38e-066144317726164
Pubmed

Qa antigens and their differential distribution on lymphoid, myeloid and stem cells.

HLA-B HLA-C HLA-E

1.38e-06614436399516
Pubmed

Polymorphism of a Qa-1-associated antigen defined by cytotoxic T cells. I. Qed-1a and Qed-1d.

HLA-B HLA-C HLA-E

1.38e-06614436978819
Pubmed

Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation.

HLA-B HLA-C HLA-E

1.38e-066144310799863
Pubmed

The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes.

HLA-B HLA-C HLA-E

1.38e-066144314595379
Pubmed

HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients.

HLA-B HLA-C HLA-DPB1

1.38e-066144319104471
Pubmed

HIV immune evasion disruption of antigen presentation by the HIV Nef protein.

HLA-B HLA-C HLA-E

1.38e-066144321762823
Pubmed

Identification of a recombinogenic major histocompatibility complex Q gene with diverse alleles.

HLA-B HLA-C HLA-E

1.38e-06614438496692
Pubmed

High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism.

HLA-B HLA-C HLA-DPB1

1.38e-066144317554059
Pubmed

Organization and structure of the Qa genes of the major histocompatibility complex of the C3H mouse: implications for Qa function and class I evolution.

HLA-B HLA-C HLA-E

1.38e-06614432767053
Pubmed

Qed-1--a target for unrestricted killing by T cells.

HLA-B HLA-C HLA-E

1.38e-06614436967411
Pubmed

The immunosuppressive peptide of HIV-1 gp41 like human type I interferons up-regulates MHC class I expression on H9 and U937 cells.

HLA-B HLA-C HLA-E

1.38e-06614439373217
Pubmed

Biochemical identification of the Qa-1 alloantigen.

HLA-B HLA-C HLA-E

1.38e-06614437026427
Pubmed

Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses.

HLA-B HLA-C HLA-E

1.38e-066144319555986
Pubmed

The clinical implications of HLA mismatches in unrelated donor haematopoietic cell transplantation.

HLA-B HLA-C HLA-DPB1

1.38e-066144318976440
Pubmed

HLA-A, B, Cw, DRB1, DQB1 and DPB1 alleles and haplotypes in the genetically homogenous Irish population.

HLA-B HLA-C HLA-DPB1

1.38e-066144318976432
Pubmed

Degenerate MHC restriction reveals the contribution of class I MHC molecules in determining the fine specificity of CTL recognition of an immunodominant determinant of HIV-1 gp160 V3 loop.

HLA-B HLA-C HLA-E

1.38e-06614439120272
Pubmed

Embryonal carcinoma cells express Qa and Tla class I genes of the major histocompatibility complex.

HLA-B HLA-C HLA-E

1.38e-06614432740345
Pubmed

Chemosensory recognition of phenotypes determined by the Tla and H-2K regions of chromosome 17 of the mouse.

HLA-B HLA-C HLA-E

1.38e-06614436961454
Pubmed

Clonal analysis of the anti-Qa-1 cytotoxic T lymphocyte repertoire: definition of the Qa-1d and Qa-1c alloantigens and cross-reactivity with H-2.

HLA-B HLA-C HLA-E

1.38e-06614432416805
Pubmed

On the role of the second coding exon of the HIV-1 Tat protein in virus replication and MHC class I downregulation.

HLA-B HLA-C HLA-E

1.38e-06614439840288
Pubmed

A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160.

HLA-B HLA-C HLA-E

1.38e-06614432789433
Pubmed

Spatial and functional relationship of GGAs and AP-1 in Drosophila and HeLa cells.

HLA-B HLA-C HLA-E

1.38e-066144319847956
Pubmed

Recognition of alternate alleles and mapping of the Qa1 locus.

HLA-B HLA-C HLA-E

1.38e-06614437276576
Pubmed

Repression of MHC class I gene promoter activity by two-exon Tat of HIV.

HLA-B HLA-C HLA-E

1.38e-06614438493575
Pubmed

Developmental expression of the mouse MHC Q genes.

HLA-B HLA-C HLA-E

1.38e-06614438732475
Pubmed

Minor contribution of HLA class I-associated selective pressure to the variability of HIV-1 accessory protein Vpu.

HLA-B HLA-C HLA-E

1.38e-066144322503975
Pubmed

Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

HLA-B HLA-C HLA-E

1.38e-06614439368027
Pubmed

Allele frequencies and haplotypic associations defined by allelic DNA typing at HLA class I and class II loci in the Japanese population.

HLA-B HLA-C HLA-DPB1

1.38e-066144311169242
Pubmed

Three regions of HIV-1 gp160 contain clusters of immunodominant CTL epitopes.

HLA-B HLA-C HLA-E

1.38e-06614438877415
Pubmed

Impact of HLA-DPB1 allelic and single amino acid mismatches on HSCT.

HLA-B HLA-C HLA-DPB1

1.38e-066144318544086
Pubmed

HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population.

HLA-B HLA-C HLA-DPB1

1.38e-066144311984513
Pubmed

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein.

HLA-B HLA-C HLA-E

1.38e-06614438612235
Pubmed

Strategies for inhibiting function of HIV-1 accessory proteins: a necessary route to AIDS therapy?

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G

1.51e-0647144519149577
Pubmed

HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41.

HLA-B HLA-C HLA-DPB1 HLA-E

1.60e-062114448084338
Pubmed

HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells.

HLA-B HLA-C HLA-E IFNB1

1.95e-062214447913356
Pubmed

Role of HIV-1 Nef protein for virus replication in vitro.

HLA-B HLA-C HLA-DPB1 HLA-E

2.35e-0623144419770068
Pubmed

DNA sequences of mouse H-2 and Qa genes.

HLA-B HLA-C HLA-E

2.40e-06714432592022
Pubmed

Generation of a functional cDNA encoding the LdH2 class-I molecule by using a single-LTR retroviral shuttle vector.

HLA-B HLA-C HLA-E

2.40e-06714431705528
Pubmed

Further studies on polymorphic expression of GM1 and GD1a in mouse liver. The presence of a third allele on the Ggm-1 locus.

HLA-B HLA-C HLA-E

2.40e-06714432808323
Pubmed

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules.

HLA-B HLA-C HLA-E

2.40e-06714439586638
Pubmed

CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.

HLA-B HLA-C HLA-E

2.40e-067144321088134
Pubmed

The Tla locus: a new allele and antigenic specificity.

HLA-B HLA-C HLA-E

2.40e-067144369663
Pubmed

Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense.

HLA-B HLA-C HLA-E

2.40e-067144312459592
Pubmed

Multiple sequences related to classical histocompatibility antigens in the mouse genome.

HLA-B HLA-C HLA-E

2.40e-06714436264319
Pubmed

Sequence analysis of the C3H H-2K1k gene: relationship to the H-2 loci.

HLA-B HLA-C HLA-E

2.40e-06714432714856
Pubmed

Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells.

HLA-B HLA-C HLA-E

2.40e-067144310500200
Pubmed

Structural analysis of H-2Kf and H-2Kfm1 by using H-2K locus-specific sequences.

HLA-B HLA-C HLA-E

2.40e-06714432391419
Pubmed

HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China.

HLA-B HLA-C HLA-DPB1

2.40e-067144317900288
Pubmed

Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmunosuppressed adult rats.

HLA-B HLA-C HLA-E

2.40e-067144315671142
InteractionHLA-H interactions

HLA-B HLA-C HLA-E PTPRO

4.67e-06171384int:HLA-H
Cytoband6p21.3

HLA-B HLA-C HLA-DPB1 HLA-E WDR46 PSMB8

1.52e-0425014566p21.3
GeneFamilyRAB, member RAS oncogene GTPases

RAB25 RAB4B RAB30 RAB43 RAB39A RAB39B RAB4A

3.84e-0865927388
GeneFamilyC1-set domain containing

HLA-B HLA-C HLA-DPB1 HLA-E

6.06e-0542924591
GeneFamilyHistocompatibility complex|C1-set domain containing

HLA-B HLA-C HLA-DPB1 HLA-E

7.29e-0544924588
GeneFamilyRNA binding motif containing

TRA2B PABPC4L DND1 PABPN1 PABPC1L CPSF7

7.66e-04213926725
GeneFamilyApolipoprotein B mRNA editing enzyme catalytic subunits

APOBEC3G APOBEC3F

1.64e-0312922406
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D8B NSMAF

1.93e-03139221146
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS9 ADAMTS16

4.14e-031992250
CoexpressionZHONG_PFC_MAJOR_TYPES_MICROGLIA

DOCK2 RAPGEF6 MAN2B1 HLA-B HLA-C TMC6 HLA-E RNF213 CCND1 STING1 SLC7A7 LTC4S

4.33e-0643814012M39077
CoexpressionTABULA_MURIS_SENIS_LUNG_PULMONARY_INTERSTITIAL_FIBROBLAST_AGEING

HLA-B HLA-C HLA-E PSMB8

7.62e-06241404MM3773
CoexpressionRUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP

HLA-B HLA-C HLA-E LTC4S

9.04e-06251404MM672
CoexpressionGSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_DN

HLA-B HLA-DPB1 HLA-E PSMB8 STING1 SAMD9L RAB4B MDGA1

9.74e-061931408M6150
CoexpressionGSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN

B4GALNT4 PSMB8 APEH STARD7 RASGEF1B RAB39A RINL RASGRP2

1.26e-052001408M7780
CoexpressionGSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN

HLA-B CCND1 API5 LRP1B CELSR1 PABPN1 RAB43 CRTAP

1.26e-052001408M6583
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_3_PRECICTIVE_ICB_RESPONSE

LANCL3 DLGAP2 MAP1A HLA-B HLA-C HLA-E CCND1 TEX26

1.86e-052111408MM17081
CoexpressionKIM_LRRC3B_TARGETS

HLA-B HLA-C HLA-DPB1 HLA-E

1.92e-05301404M17363
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN

B4GALNT4 HLA-B HLA-C HLA-E WSCD2 LOXL4

1.95e-051031406MM476
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_MICROGLIA

DOCK2 MAN2B1 HLA-B HLA-C HLA-E RNF213 CCND1 STING1 SLC7A7 LTC4S

3.22e-0537114010M39022
CoexpressionBLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_DEL_NS1_INFECTION_UP

HLA-B HLA-C FA2H HLA-E PSMB8 APOBEC3G RNF213 APOBEC3F SAMD9L ADPRM RASGEF1B EXOC3L1 TENT2

4.36e-0564414013M34026
CoexpressionSANA_RESPONSE_TO_IFNG_UP

HLA-B HLA-C HLA-E RNF213 SAMD9L

5.51e-05761405M4551
CoexpressionCROONQUIST_NRAS_VS_STROMAL_STIMULATION_UP

SLC7A7 RAB4B PLEC RASGRP2

6.77e-05411404M8273
CoexpressionTABULA_MURIS_SENIS_LUNG_ENDOTHELIAL_CELL_OF_LYMPHATIC_VESSEL_AGEING

HLA-B HLA-C HLA-E

7.94e-05161403MM3766
CoexpressionRODWELL_AGING_KIDNEY_UP

DOCK2 MAN2B1 HLA-B TMC6 HLA-E WDR46 PSMB8 RNF213 STING1 SAMD9L RAB4B

8.25e-0550114011M5389
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9

RAB25 HLA-B HLA-C HLA-E PSMB8

9.42e-05851405MM1279
CoexpressionRUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP

HLA-B HLA-E LTC4S

9.60e-05171403M1581
CoexpressionGSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP

DOCK2 FA2H APEH SPATA17 TMTC4 DHPS CRTAP

9.72e-051981407M4736
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN

EXOSC9 ADGRG3 RAPGEF6 AKAP11 PLEC RNF128 ANAPC5

1.00e-041991407M8100
CoexpressionGSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN

HLA-E RNF213 RASGEF1B FGF11 RINL RAB4A CRTAP

1.00e-041991407M7485
CoexpressionGSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN

EPHB2 GPAA1 HLA-B HLA-C HLA-E SLC7A7 PABPN1

1.03e-042001407M3638
CoexpressionGSE3039_NKT_CELL_VS_B2_BCELL_UP

STAB2 TMC6 API5 PIKFYVE AKAP11 NSMAF RASGRP2

1.03e-042001407M6435
CoexpressionGSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP

DOCK2 HLA-B CCND1 SAMD9L PTPRO GPSM2 ANAPC5

1.03e-042001407M6625
CoexpressionGSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN

HLA-B HLA-C API5 PLXNB2 PABPN1 RAB43 CRTAP

1.03e-042001407M6587
CoexpressionGSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_UP

FA2H STING1 PHEX SPATA17 PDP2 CPLANE1 ANAPC5

1.03e-042001407M6586
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP

DOCK2 GPAA1 MAN2B1 HLA-C QSOX1 RAB4B RAB43

1.03e-042001407M10032
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

DOCK2 RAPGEF6 TRA2B HLA-B HLA-C HLA-DPB1 TMC6 HLA-E PSMB8 APOBEC3G RNF213 STING1 OGG1 CYRIB APOBEC3F PIKFYVE SAMD9L AKAP11 NSMAF RASGRP2

1.33e-04149214020M40023
CoexpressionWUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_DN

HLA-B HLA-C HLA-E

1.36e-04191403MM797
CoexpressionMIKKELSEN_NPC_ICP_WITH_H3K27ME3

HLA-B HLA-C HLA-E

1.36e-04191403MM862
CoexpressionBAUS_TFF2_TARGETS_UP

HLA-B HLA-C HLA-E PSMB8

1.37e-04491404MM1287
CoexpressionTABULA_MURIS_SENIS_BLADDER_LEUKOCYTE_AGEING

HLA-B HLA-C HLA-E

1.59e-04201403MM3682
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_OVERLAP_UP

HLA-B HLA-C HLA-E PSMB8 DNASE1L3

1.84e-04981405MM460
CoexpressionRUAN_RESPONSE_TO_TNF_UP

HLA-B HLA-C HLA-E

1.85e-04211403MM651
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_UP

HLA-B HLA-C HLA-E PSMB8 DNASE1L3

2.03e-041001405MM458
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_25_PRECICTIVE_ICB_RESPONSE

DOCK2 MAN2B1 HLA-B TDRD9 HLA-C HLA-E STING1

2.14e-042251407MM17079
CoexpressionHU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR

HLA-B HLA-C HLA-E API5

2.64e-04581404MM661
CoexpressionGSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_DN

NUP107 OGG1 KIFAP3 GYS1 DHPS AQR

2.66e-041651406M353
CoexpressionTABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_B_CELL_AGEING

MAN2B1 HLA-B HLA-C HLA-E PSMB8 RAB43 AQR RASGRP2

2.77e-043111408MM3674
CoexpressionJEON_SMAD6_TARGETS_UP

PSMB8 LAMC2 QSOX1

2.78e-04241403M4592
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K0

STAB2 HLA-B HLA-C RAPGEF4 PSMB8 SAMD9L GALNT17

1.58e-051221397facebase_RNAseq_e10.5_MaxArch_2500_K0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-B HLA-C TMC6 HLA-E APOBEC3G CCND1 STING1 RASGRP2

8.70e-08174141866a3b20ff1ab9f36fb391986444d7dc99d0c03d1
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

HLA-B HLA-C HLA-E PSMB8 RNF213 APOBEC3F IFNB1 SAMD9L

1.78e-0719114182da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAN2B1 HLA-B HLA-C HLA-DPB1 HLA-E CYRIB LTC4S DNASE1L3

1.78e-07191141887b974a320888d63aa8cefcd8dc97d525b56d848
ToppCellCV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

HLA-B HLA-C HLA-DPB1 HLA-E PSMB8 APOBEC3G RNF213 SAMD9L

1.85e-0719214182a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-B TSPOAP1 HLA-E RNF213 SAMD9L CPLANE1 TENT2

1.57e-061771417d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-B TSPOAP1 HLA-E RNF213 SAMD9L CPLANE1 TENT2

1.57e-061771417f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

HLA-B TSPOAP1 HLA-E RNF213 SAMD9L CPLANE1 TENT2

1.57e-0617714176978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-B TSPOAP1 HLA-E RNF213 SAMD9L CPLANE1 TENT2

1.57e-061771417936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-B TSPOAP1 HLA-E RNF213 SAMD9L CPLANE1 TENT2

1.57e-061771417d5aeda113afaa2425874394610344570c9078478
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

HLA-B TSPOAP1 HLA-E RNF213 SAMD9L CPLANE1 TENT2

1.96e-06183141722bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

HLA-B TSPOAP1 HLA-DPB1 HLA-E RNF213 TMEM151A TENT2

2.03e-061841417791f1bcb954aadc63d4117c400537d036f68734d
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG3 STAB2 HLA-B HLA-C HLA-E ADAMTS9 EXOC3L1

2.11e-061851417fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 CHN1 LRP1B ADAMTS9 EXOC3L1 LTC4S CDH7

2.69e-06192141781baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell3'-Pediatric_IBD|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-B HLA-C HLA-DPB1 HLA-E PSMB8 RNF213 SAMD9L

2.99e-061951417728776511e1f40f127f80ef1eecda6d6ad082392
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid-Microglia|GW08 / Sample Type, Dataset, Time_group, and Cell type.

DOCK2 MAN2B1 PSMB8 RNF213 STING1 SLC7A7 LTC4S

3.09e-06196141789a0ccd0684777927d99d5fc5b7c498f3f124250
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid|GW08 / Sample Type, Dataset, Time_group, and Cell type.

DOCK2 MAN2B1 PSMB8 RNF213 STING1 SLC7A7 LTC4S

3.09e-06196141791a8c4798572d6c1f03cef5e8e5464ed0046c7cf
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 HLA-B HLA-C HLA-E RNF213 CYRIB SAMD9L

3.41e-061991417155b03b859157013e9142e9248551369127d9204
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial|GW16 / Sample Type, Dataset, Time_group, and Cell type.

TMC6 APOBEC3G STING1 ZSCAN25 SLC7A7 APOBEC3F RASGRP2

3.53e-06200141725f4c051c2e869481f33c22ad54de97efac444ad
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD3|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 B4GALNT4 HLA-B HLA-C PABPC4L FGF8 RASGRP2

3.53e-0620014176b34f2b85d4f83c1270ee151f602cba6f42042ba
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD3-NKT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK2 B4GALNT4 HLA-B HLA-C PABPC4L FGF8 RASGRP2

3.53e-062001417b2c5618aa1ac19423996336795dadb39ea57cda7
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

TMC6 APOBEC3G STING1 ZSCAN25 SLC7A7 APOBEC3F RASGRP2

3.53e-062001417da45a85a4667965b24ba824af871157af5b4cd19
ToppCellkidney_cells-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-B HLA-C HLA-DPB1 RAPGEF4 HLA-E LTC4S DNASE1L3

3.53e-0620014179f1626a7e1bd00977a5c316cafbdf654b52bad94
ToppCellCOVID-19_Convalescent-CD8+_Tem|COVID-19_Convalescent / Disease condition and Cell class

HLA-B HLA-C HLA-DPB1 HLA-E PSMB8 APOBEC3G RNF213

3.53e-0620014171cf2234d5add07e1cd560ca3efa8aafd0851921d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TBC1D8B ADAMTS9 PTPRO AGTR2 FGF11 RNF128

3.69e-06130141660e28d452d0e2af768459ba8dbe998117c94a251
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GABRD DND1 IGSF10 GALNT17 WSCD2 LOXL4

4.59e-0613514165b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TBC1D8B PTPRO AGTR2 FGF11 RNF128 RASGRP2

9.06e-0615214168ff5a178a8f3550d89a003c0858820aab3773386
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DLGAP2 HLA-B HLA-C HLA-E APOBEC3G CYRIB

9.41e-06153141682a96ca1912858c4311b87b3b0ba5a0a41e564b5
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAN2B1 POLR1A PSMB8 CCND1 RAB43 DNASE1L3

1.26e-05161141676c993a4533362db2250c88b3ee3ede55362d54e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAB25 WDR46 SOWAHA RASGEF1B EXOC3L1 MDGA1

1.45e-05165141650f1fa7434ebb777e15d5273d1ff41070cff6db3
ToppCell356C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

HLA-DPB1 CCND1 IFNB1 AGTR2 DNASE1L3 KLB

1.50e-051661416971ee6602a1e751f453f9d823295e63dadce62bf
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 B4GALNT4 STAB2 TDRD9 PSMB8 RINL

1.55e-05167141653e32d6687a07f486141df9f4ab998af4c03a507
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

DLGAP2 HLA-DPB1 CCND1 RAB30 RAB39B DNASE1L3

1.66e-051691416a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCelldroplet-Lung-LUNG-30m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2B1 CCND1 SAMD9L RAB30 RAB43 DNASE1L3

1.71e-051701416ece7c20e89c190a7ec68032b6c2efeb458c43f9a
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC1|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RAB25 HLA-DPB1 CCND1 CYRIB PTPRO DNASE1L3

1.77e-051711416459e1ac0b89571c39db98c0f578eca8f46caa8e3
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLR1A CCND1 ZSCAN25 RAB30 RAB43 DNASE1L3

1.83e-051721416a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCellMild-CD4+_T_Exhausted|World / Disease group and Cell class

MAN2B1 STING1 SAMD9L ERCC6L2 IL17RD RASGRP2

1.83e-051721416efe68d9477aa873b1637ee689f298120303aa322
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|390C / Donor, Lineage, Cell class and subclass (all cells)

HLA-B HLA-C HLA-E APOBEC3G CYRIB RASGRP2

1.89e-051731416b06d6e7acb7086bb99600b680cf404c0ef06b52c
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

MAP1A PLXNB2 PHEX IGSF10 HRH2 DNASE1L3

2.08e-051761416d6e660df92a3d7dd5732171ee623763faf108476
ToppCellCOPD-Epithelial-Aberrant_Basaloid|COPD / Disease state, Lineage and Cell class

EPHB2 RAB25 LAMC2 CCND1 CELSR1 ADAMTS9

2.08e-05176141611d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

HLA-B HLA-C HLA-E RNF213 STING1 SAMD9L

2.15e-051771416a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

HLA-B HLA-C HLA-E RNF213 STING1 SAMD9L

2.22e-051781416ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|356C / Donor, Lineage, Cell class and subclass (all cells)

HLA-B HLA-C HLA-E APOBEC3G CYRIB RASGRP2

2.52e-05182141652baef8173df0a55307c375674a37c2488066738
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 HLA-B HLA-C HLA-E PSMB8 EXOC3L1

2.52e-0518214168d8f28bd43108b2fb3a6c2a3d77a897853d440a4
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM30B LANCL3 RAB25 FA2H CCND1 RNF128

2.59e-05183141603c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG3 STAB2 HLA-B HLA-C HLA-E SERPIND1

2.59e-051831416a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG3 STAB2 HLA-B HLA-C HLA-E SERPIND1

2.59e-05183141613ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARSJ RAPGEF4 LRP1B GALNT17 TMTC4 CDH7

2.67e-0518414169cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTTG1IP2 TSPOAP1 SOWAHA KCNA2 WSCD2 FGF8

2.76e-05185141630df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCell343B-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HLA-B HLA-C RAPGEF4 HLA-E SAMD9L DNASE1L3

2.84e-051861416dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRG3 STAB2 HLA-B HLA-E PSMB8 EXOC3L1

2.84e-0518614165d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG3 STAB2 HLA-B HLA-C HLA-E EXOC3L1

2.84e-0518614169d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell343B-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HLA-B HLA-C RAPGEF4 HLA-E SAMD9L DNASE1L3

2.84e-051861416080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRG3 STAB2 HLA-B HLA-E PSMB8 EXOC3L1

2.84e-0518614161da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell390C-Lymphocytic-NK_cells-NK_cell_C|390C / Donor, Lineage, Cell class and subclass (all cells)

HLA-B HLA-C HLA-E APOBEC3G RNF213 CYRIB

2.93e-0518714161e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LANCL3 UPK3BL2 RAB25 FA2H RAB39B RNF128

2.93e-05187141674112df9b34051ae5cd2427ccfa3399eccff0076
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMC2 SLC7A7 WSCD2 HRH2 LTC4S TMEM151A

2.93e-0518714168e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-B HLA-C HLA-DPB1 RAPGEF4 HLA-E CCND1

2.93e-051871416a555a4af7946dec14a6b176ace4a4c2ecfd7f59e
ToppCellfacs-Lung-EPCAM-24m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LANCL3 UPK3BL2 RAB25 FA2H RAB39B RNF128

2.93e-051871416214ce9b55fd6ce2fe7bd4cf4b1383517f5f0d759
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|(2)_5-FU / Stress and Cell class

ADGRG3 STAB2 CCND1 PABPC1L LTC4S DNASE1L3

3.11e-0518914160f169b17bb26a812a5b0dcd6e29a3ca8415fd197
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

TDRD9 STARD7 CYRIB AGBL4 GALNT17 HRH2

3.20e-0519014163729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellbackground-Cholangiocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

RAB25 ARSJ LAMC2 PLXNB2 RASGEF1B TMEM151A

3.30e-05191141699aa8d685767a72bef9f05e7cc8913126a048c39
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC1|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 HLA-B HLA-C HLA-DPB1 HRH2 DNASE1L3

3.30e-0519114169774d423e448ec2d415261e4ad386a81558129b3
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TRA2B HLA-B HLA-C HLA-DPB1 PSMB8 APOBEC3G

3.30e-0519114162ffd40ebf1d63e61a97208ddcbeb6a86e409f9d8
ToppCellCOVID-19-kidney-Myeloid|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 ADGRG3 HLA-B HLA-C HLA-E CYRIB

3.39e-051921416441cd1ec171f643b28e1f6f9c04def629cc7391b
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG3 STAB2 HLA-B HLA-C HLA-E EXOC3L1

3.39e-051921416fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 CHN1 LRP1B ADAMTS9 EXOC3L1 LTC4S

3.39e-05192141652acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG3 STAB2 HLA-B HLA-C HLA-E EXOC3L1

3.39e-0519214164e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.39e-051921416fdc741e1846cfd8ed741b160e3c611c310c5d36d
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-B HLA-DPB1 HLA-E QSOX1 LTC4S DNASE1L3

3.49e-051931416daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCellnormal_Lymph_Node-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

HLA-B HLA-C HLA-DPB1 HLA-E PSMB8 CHN1

3.49e-05193141651fd629e91c85881c3231486d6d2fb2c65fcd77b
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

MAP1A PLXNB2 PHEX HRH2 EIF2AK4 DNASE1L3

3.60e-0519414165f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG3 HLA-B HLA-C HLA-E HRH2 NSMAF

3.60e-0519414164eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RAB25 HLA-C APOBEC3G TUBGCP6 RAB4B RAB43

3.60e-0519414165031f324628ff12a33e84cc52157be4786e0961d
ToppCellnormal_Pleural_Fluid-T/NK_cells-Exhausted_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

HLA-B HLA-C HLA-E PSMB8 APOBEC3G RNF213

3.60e-05194141668a9e00c9e1a855eeebfc26c038652f3800758db
ToppCellIIF-Lymphocyte-T_NK-CD8_TEM|IIF / Disease, Lineage and Cell Type

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.60e-051941416f4f7c85963ba52ee7ca2ef5657e60680fe6332fe
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-CD8_TEM|Multiple_Sclerosis / Disease, Lineage and Cell Type

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.60e-051941416fa53f1aab2f5923e90f090e10e3560b583441dc4
ToppCellnormal_Pleural_Fluid-T/NK_cells-CD8_low_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

HLA-B HLA-C HLA-E APOBEC3G RNF213 STING1

3.60e-05194141611eb317f66cbced1cedadd6daba443c4d832c49f
ToppCell(1)_T_cells-(1)_T_CD8_activated|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

HLA-B HLA-C HLA-E APOBEC3G RNF213 CYRIB

3.60e-051941416e3f288b58525c1f34db4459d3e83e0df695adfc7
ToppCellerythropoietic-CD34+_Pro-erythroblast|erythropoietic / Lineage and Cell class

HLA-B HLA-DPB1 HLA-E PSMB8 IGSF10 RASGRP2

3.70e-051951416cd3d8fa6e18c0508cdfb64bb879d90b211badee5
ToppCellControl-CD8+_Tem|Control / Disease condition and Cell class

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.70e-0519514167503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCellmedial-2-Hematologic-IGSF21+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPHB2 HLA-DPB1 CHST13 HRH2 RAB39A LTC4S

3.70e-051951416bb612979360b2322289545dda3d3c343d005ee6f
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / Disease condition and Cell class

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.70e-051951416ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCellT_cells-GZMK+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.70e-051951416003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCellwk_20-22-Hematologic_Lymphocytic-NK-CD16+_NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HLA-B HLA-C HLA-E APOBEC3G RNF213 CYRIB

3.70e-0519514167533822d2fe551f499b5b2fdec7172f56c79cb44
ToppCellmedial-Hematologic-IGSF21+_Dendritic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPHB2 HLA-DPB1 CHST13 HRH2 RAB39A LTC4S

3.70e-051951416779130c2cfcbc603955b0c0332b855b22ab6e9e6
ToppCellmedial-Hematologic-IGSF21+_Dendritic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPHB2 HLA-DPB1 CHST13 HRH2 RAB39A LTC4S

3.70e-051951416330b688d703d53cb7feb29373b5a6e6e529169ec
ToppCellSubstantia_nigra-Neuronal-Excitatory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GABRD RAB25 ARSJ DND1 PABPC1L

3.71e-0511814159f1d744f46d79ff2ab7f168f54fdbd9f4640dddd
ToppCellCV-Moderate-1|Moderate / Virus stimulation, Condition and Cluster

HLA-B HLA-C HLA-E PSMB8 RNF213 SAMD9L

3.81e-051961416b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCellsevere-CD8+_Tem|severe / disease stage, cell group and cell class

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.81e-0519614169456a5879948e25bc483a7233c274da841ef2c68
ToppCellmedial-Endothelial-Capillary_Intermediate_2-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-B HLA-C HLA-E CCND1 RAB43 DNASE1L3

3.81e-0519614165cc14a5797884ff3a007683048e690a0d7172fc4
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.81e-0519614160f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCellmedial-Endothelial-Capillary_Intermediate_2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-B HLA-C HLA-E CCND1 RAB43 DNASE1L3

3.81e-05196141607e6214e771c65574f0ada65e75f4bda265aa47f
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.81e-0519614164e1f8828413896ab8a4ec92a89d6789e8e37e05a
ToppCellmedial-2-Endothelial-Capillary_Intermediate_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HLA-B HLA-C HLA-E CCND1 RAB43 DNASE1L3

3.81e-051961416d074c24fecd0e3ffca4699fb1a9d443e6d9a858d
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HLA-B HLA-C HLA-DPB1 HLA-E RAB30 RASGEF1B

3.81e-0519614169a6e4eea19348a6e3379d3b872456ab6280cb74f
ToppCellwk_20-22-Hematologic_Lymphocytic|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HLA-B HLA-C HLA-E PSMB8 APOBEC3G RASGRP2

3.92e-05197141677107345c766451302e21f7cbd45316f4131a0e8
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.92e-0519714162b3a56bb1d40bc1284a5931c4e7b373660de5402
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_Tem|COVID-19_Severe / Disease group, lineage and cell class

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.92e-051971416f0bac4d5c3160933ac3786cec8dadffb35d711ea
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-B HLA-C HLA-DPB1 HLA-E APOBEC3G RNF213

3.92e-051971416f73ece3aca28c0db5db0f12e026d42c6c36b9efb
ToppCellCV-Moderate-1|CV / Virus stimulation, Condition and Cluster

HLA-B HLA-C HLA-E PSMB8 RNF213 SAMD9L

3.92e-051971416e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ComputationalNeighborhood of CD48

DOCK2 HLA-B HLA-C HLA-E PSMB8

2.35e-0632745GNF2_CD48
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HLA-B HLA-C HLA-DPB1 HLA-E PSMB8

2.24e-0550745GAVISH_3CA_MALIGNANT_METAPROGRAM_17_INTERFERON_MHC_II_1
ComputationalNeighborhood of CD53

DOCK2 HLA-B HLA-C HLA-E PSMB8

4.65e-0558745GNF2_CD53
ComputationalGenes in the cancer module 293.

HLA-B HLA-C HLA-E

6.59e-0512743MODULE_293
ComputationalNeighborhood of VAV1

DOCK2 HLA-B HLA-C HLA-E

1.03e-0436744GNF2_VAV1
ComputationalGenes in the cancer module 143.

HLA-B HLA-C HLA-E

1.08e-0414743MODULE_143
ComputationalNeighborhood of STAT6

DOCK2 HLA-B HLA-C HLA-E PSMB8

2.05e-0479745GNF2_STAT6
ComputationalNeighborhood of INPP5D

HLA-B HLA-C HLA-E PSMB8

2.08e-0443744GNF2_INPP5D
ComputationalNeighborhood of PTPN6

HLA-B HLA-C HLA-E CYRIB

2.95e-0447744GNF2_PTPN6
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HLA-B HLA-C HLA-DPB1 HLA-E

3.75e-0450744GAVISH_3CA_METAPROGRAM_EPITHELIAL_INTERFERON_MHC
ComputationalNeighborhood of ATM

RAPGEF6 TMC6 RASGRP2

1.11e-0330743GNF2_ATM
ComputationalNeighborhood of TERF1

GPAA1 STARD7 PABPN1 ANAPC5

1.14e-0367744MORF_TERF1
Diseaseoccupational asthma (is_implicated_in)

HLA-B HLA-DPB1 HLA-E

3.57e-0741333DOID:0080820 (is_implicated_in)
Diseaseallergic asthma (is_implicated_in)

HLA-B HLA-C HLA-DPB1

8.89e-0751333DOID:9415 (is_implicated_in)
Diseasegraft-versus-host disease (implicated_via_orthology)

HLA-B HLA-C HLA-E

3.09e-0671333DOID:0081267 (implicated_via_orthology)
DiseaseDNA dC->dU-editing enzyme APOBEC-3G measurement

APOBEC3G APOBEC3F

6.03e-0531332EFO_0802473
DiseaseCOVID-19 (is_implicated_in)

HLA-B HLA-C IFNB1

1.12e-04211333DOID:0080600 (is_implicated_in)
Diseasefactor VIII measurement, von Willebrand factor measurement

STAB2 HLA-C AK8

2.42e-04271333EFO_0004629, EFO_0004630
DiseaseMyasthenia Gravis

HLA-B HLA-DPB1

2.99e-0461332C0026896
DiseaseMyasthenia Gravis, Ocular

HLA-B HLA-DPB1

2.99e-0461332C0751340
DiseaseMyasthenia Gravis, Generalized

HLA-B HLA-DPB1

2.99e-0461332C0751339
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

NUP107 TBC1D8B PTPRO

3.32e-04301333C1868672
DiseaseMental Retardation, X-Linked 1

AGTR2 RAB39B MED12

4.04e-04321333C2931498
Diseasesensorineural hearing loss (is_implicated_in)

HLA-B GPSM2 MYO15A

4.42e-04331333DOID:10003 (is_implicated_in)
Diseasecervical cancer

HLA-DPB1 CCND1 PIAS3

4.84e-04341333C4048328
DiseaseUterine Cervical Neoplasm

HLA-DPB1 CCND1 PIAS3

5.27e-04351333C0007873
DiseaseUrologic Neoplasms

CCND1 OGG1

5.55e-0481332C0042076
DiseaseCancer of Urinary Tract

CCND1 OGG1

5.55e-0481332C0751571
DiseaseHepatitis B, Chronic

HLA-C HLA-DPB1

5.55e-0481332C0524909
DiseaseCarcinoma, Transitional Cell

CCND1 IFNB1 HRH2

8.42e-04411333C0007138
Diseasebeta-2 microglobulin measurement

HLA-B HLA-C

1.08e-03111332EFO_0005197
Diseasebipolar disorder

DOCK2 DLGAP2 POLR1A HLA-B TDRD9 SPATA17 MKLN1 WSCD2 PLEC

1.25e-035771339MONDO_0004985
Diseasedermatomyositis

HLA-B HLA-DPB1

1.29e-03121332EFO_0000398
DiseaseAmino Acid Metabolism, Inherited Disorders

SLC7A7 EIF2AK4

1.52e-03131332C0750905
DiseaseAmino Acid Metabolism, Inborn Errors

SLC7A7 EIF2AK4

1.52e-03131332C0002514
DiseaseAsthma, Aspirin-Induced

HLA-DPB1 LTC4S

1.52e-03131332C1319853
Diseasedystonia (is_implicated_in)

TSPOAP1 TMEM151A

1.77e-03141332DOID:543 (is_implicated_in)
DiseaseMalignant neoplasm of prostate

EPHB2 STAB2 SRD5A2 CCND1 OGG1 LRP1B RAB4B IL17RD MED12

1.96e-036161339C0376358
Diseaseliver neoplasm

HLA-B HLA-DPB1

2.04e-03151332EFO_1001513
Diseasesevere aplastic anemia

HLA-B HLA-DPB1

2.04e-03151332EFO_0006927
Diseasehead and neck squamous cell carcinoma (is_implicated_in)

CCND1 OGG1

2.04e-03151332DOID:5520 (is_implicated_in)
Diseasekiller cell immunoglobulin-like receptor 2DS2 measurement

HLA-B HLA-C

2.04e-03151332EFO_0801746
Diseaseadverse effect, response to xenobiotic stimulus

STAB2 LRP1B KIFAP3

2.42e-03591333EFO_0009658, GO_0009410
Diseaseserum IgG glycosylation measurement

DOCK2 STAB2 HLA-C LRP1B ERCC6L2 MDGA1 TENT2 NSMAF

2.62e-035231338EFO_0005193
DiseaseMoyamoya Disease

HLA-B RNF213

2.62e-03171332C0026654
Diseaseacute pancreatitis

TBC1D8B RNF128

2.94e-03181332EFO_1000652
Diseaseunipolar depression

B4GALNT4 HLA-B TDRD9 HLA-E RNF213 AK8 TUBGCP6 AGBL4 GALNT17 RASGEF1B MKLN1 MED12 CRTAP

3.20e-03120613313EFO_0003761
Diseasehepatitis B virus infection

HLA-C HLA-DPB1

3.28e-03191332EFO_0004197
DiseaseNeoplasms, Experimental

CCND1 IFNB1 HRH2

3.33e-03661333C0027659
DiseaseProstate cancer, familial

EPHB2 DOCK2 SRD5A2

3.78e-03691333C2931456
Diseasethyroid peroxidase antibody measurement

HLA-DPB1 ERCC6L2 HRH2

4.26e-03721333EFO_0005666
Diseaseperceived unattractiveness to mosquitos measurement

RAPGEF6 HLA-B CDH7

4.26e-03721333EFO_0008380

Protein segments in the cluster

PeptideGeneStartEntry
FSQRGYYLTLRANRV

UPK3BL1

111

B0FP48
FYRPEQLARLGQYRS

EXOC3L1

41

Q86VI1
ETGQGYQRFLLYNRS

APOM

136

O95445
LRPRVNYLQDFSYQR

ERVK-9

201

Q9UKH3
QLRRYTAQLLSGLDY

EIF2AK4

401

Q9P2K8
TFSYNFYNRPILSRR

APOBEC3G

16

Q9HC16
DRYQSVIYPFLSQRR

AGTR2

141

P50052
AFNGTQRFLERYIYN

HLA-DPB1

46

P04440
NSYGLYTIRDRENRT

ADGRG3

401

Q86Y34
QYANRLAYRSVKSGL

AKAP11

1366

Q9UKA4
LEDGFNFQGTRRRYY

ADPRM

31

Q3LIE5
NFQGTRRRYYRHSLL

ADPRM

36

Q3LIE5
RTQGLFSYREDYRTQ

DLGAP2

821

Q9P1A6
VGIRNTFLLRTYAYL

TENT2

286

Q6PIY7
DFSRYGRVNYVLARR

AQR

891

O60306
NNFLSYYRLTRFLSR

CCND1

221

P24385
RLQYFARGLQVYIRQ

API5

376

Q9BZZ5
EGYFSNVARNVRRTY

CELSR1

2221

Q9NYQ6
RGRIYYAKFINTNAR

C2orf73

46

Q8N5S3
ISVRNALRRYYLNGH

ADAMTS16

786

Q8TE57
LERYRAITSAYYRGA

RAB25

71

P57735
GQERFRSITRSYYRN

RAB39A

71

Q14964
AGQERFRSITRAYYR

RAB39B

66

Q96DA2
FRSITRAYYRNSVGG

RAB39B

71

Q96DA2
SLRHYLNLVTRQRYG

PYY

51

P10082
AGQERFRSITQSYYR

RAB30

66

Q15771
GQERFRTITQSYYRS

RAB43

76

Q86YS6
GQERFRSVTRSYYRG

RAB4A

71

P20338
GQERFRSVTRSYYRG

RAB4B

66

P61018
RSFYTAYLQRLSGLT

QSOX1

256

O00391
GGARIQVFLARYSYN

TSPOAP1

651

O95153
LYTYSGLRNRRAAVY

CPSF7

71

Q8N684
NRYERAIYAALSGNL

NUP107

421

P57740
RLYYLRNGERISVSA

PSMB8

136

P28062
RRNFGYTLRSVNDLY

SERPIND1

211

P05546
YGRSLRYAALNLAAL

ANAPC5

296

Q9UJX4
TYRCQTARYNGFNVR

MDGA1

511

Q8NFP4
RVNLRTLRGYYNQSE

HLA-E

96

P13747
DAILYYYQSGGRLRR

KCNA2

86

P16389
YGYRRLLRFSTQIYN

LOXL4

576

Q96JB6
AEQESGLYRYRSRNS

MDN1

3546

Q9NU22
ERRAYSNLGNAYIFL

GPSM2

241

P81274
RNYFRSKSGRSLYVA

IL17RD

531

Q8NFM7
YNQRRKGTNRIFYSD

LRP1B

2231

Q9NZR2
QRYRSLFLSGSKRYL

LEXM

371

Q3ZCV2
FFRRVRASYYVVSGN

MAP1A

2711

P78559
ALTLRGINSFRQYKY

GPAA1

316

O43292
YGNYRRRLAACVGFR

RASGRP2

286

Q7LDG7
LLQSRARGYLARQRY

MYO15A

1931

Q9UKN7
GRYFEHYRSIININR

ARSJ

276

Q5FYB0
FQVRARTVAGYGRYS

EPHB2

506

P29323
GRQTYDYRNIRISFG

EXOSC9

26

Q06265
QADRVSLRNLRGYYN

HLA-C

96

P10321
FSYTATEARRLYLQR

AK8

96

Q96MA6
LLLRRGNIFLTSYQY

PLXNB2

596

O15031
LRYFQGYARSAQLRL

LTC4S

91

Q16873
AYLYARFNRISRIRA

OPTC

156

Q9UBM4
ILYAALNRDFRTGYQ

HRH2

286

P25021
LTGNSKYIYRAQRFA

LANCL3

356

Q6ZV70
NTNRPRTARASARYY

LCT

1341

P09848
LRYSGEFVQSAYLSR

MED12

281

Q93074
AFTSGLRRYLQYYRA

TUBGCP6

431

Q96RT7
FHLRRNRGVYIIQSY

GABRD

241

O14764
LGYRARYVSASARAI

OGG1

201

O15527
VATRRSLGYAYINFQ

PABPC1L

46

Q4VXU2
YNYRTALRGAAQRSL

RASGEF1B

346

Q0VAM2
QTDRESLRNLRGYYN

HLA-B

96

P01889
NRYTNILPYDFSRVR

PTPRO

966

Q16827
QDLNRNRVYFYGRRE

PTTG1IP2

126

P0DTF9
LYASALYRQRRSGRA

FGF11

156

Q92914
SYYRTFAQGNVRLFT

FA2H

186

Q7L5A8
FPRARYRARTTNYNS

PABPN1

261

Q86U42
QGGRRLYSRYVSNRN

PDP2

21

Q9P2J9
YVLFRSIQRSRAGYC

FAM189B

361

P81408
RRLIRTYQLYSRTSG

FGF8

66

P55075
LELRFYGHQYTRRAN

PIKFYVE

1341

Q9Y2I7
TFSYNFYNRPILSRR

APOBEC3F

16

Q8IUX4
RVAGNTAYYQLRDRV

ADAMTS9

691

Q9P2N4
HRTRRYTLFNNGTLY

IGSF10

2091

Q6WRI0
STALNRGEQRAVRYY

GPATCH11

6

Q8N954
NRNSRRGITYNYVIS

DNASE1L3

76

Q13609
SNYVQRFHYSRPVRR

DOCK2

1436

Q92608
GGRRTYFLQIRYYLS

CPLANE1

861

Q9H799
LRPRVNYLQDFSYQR

ERVK-7

91

P61567
LRAGRAQYERYSFRS

CRTAP

21

O75718
VRGYDFNRGVNYRAL

DHPS

31

P49366
ALLFRSARQYVYGVL

FAM120C

651

Q9NX05
ILRNFYFINRLTGYL

IFNB1

171

P01574
TFRKLYARIRQGNYS

TMEM30B

261

Q3MIR4
LGRNVARTFLDYYRL

AGBL4

426

Q5VU57
YNSNIGFYTKRNALR

GALNT17

386

Q6IS24
LRPRVNYLQDFSYQR

ERVK-21

201

P61565
LRPRVNYLQDFSYQR

ERVK-5

91

Q9HDB8
FLNVATAQGRYYRTN

MAN2B1

296

O00754
AYARYSSRRGAQAAI

DND1

101

Q8IYX4
VYFYSIAFGRRQDTL

NSMAF

696

Q92636
GYSNRLYFVNLRTRD

KLHDC1

91

Q8N7A1
NRQALRYYRCVVSEG

KLB

616

Q86Z14
RNLTALRIRATYGEY

LAMC2

341

Q13753
AIQNDFSYYRRTLSR

CYRIB

151

Q9NUQ9
RRNGFRRQEQSVYYL

CDH7

546

Q9ULB5
NRYLRDYQREGTRFL

ERCC6L2

131

Q5T890
LRFGSQTRNFRLYYD

CHN1

86

P15882
SAYGIYILDRRFRSL

GYS1

546

P13807
LYAAYHVFFGRRRQA

RXYLT1

21

Q9Y2B1
QLLYYLQNRRDSLSG

KIFAP3

91

Q92845
LGVYTRNRNFRLYKS

PRIMPOL

281

Q96LW4
VTRRSLGYAYVNFLQ

PABPC4L

46

P0CB38
RLQARSSTVGNQYYF

SPATA17

6

Q96L03
NTARTVRYYRSQPFN

RAPGEF4

956

Q8WZA2
YNNLLRGAVSQRLYI

STING1

186

Q86WV6
FSQRGYYLTLRANRV

UPK3BL2

111

E5RIL1
ARARYERYSGNQVLF

RAPGEF6

51

Q8TEU7
LARLFTAYLQLYRGF

POLR1A

781

O95602
QRYFRAQVLYVSGNS

TDRD9

961

Q8NDG6
QRRQIYTLGRYLDSS

MKLN1

336

Q9UL63
YVSSLNRSFRGQYKR

SAMD9L

1451

Q8IVG5
ATVGYFIFYSARRLR

RNF128

221

Q8TEB7
NLTSLRRLYLNGNYL

SLITRK2

421

Q9H156
QILQREGTRALYRGY

SLC25A41

231

Q8N5S1
RTRQITRYRNGDAYT

TMEM151A

161

Q8N4L1
GDRTRRSYYLNEIQS

SPATC1L

171

Q9H0A9
GIRFCTNRRSALYYV

APEH

271

P13798
AARLPRYQYLRRTGN

B4GALNT4

876

Q76KP1
RYQYLRRTGNFERSA

B4GALNT4

881

Q76KP1
NKLARPYSAAFQRRY

CHST13

186

Q8NET6
FGRNYSLSVYLVRQL

PIAS3

266

Q9Y6X2
LVRARSSYVARQYRS

RINL

266

Q6ZS11
SETFQRPYQYLRRFN

RNF213

2161

Q63HN8
LERASQYNIRGVTYR

UBA3

286

Q8TBC4
GNQTAAIRYYREAVR

TMTC4

496

Q5T4D3
IRNRGYNLIYRSTRH

TMEM192

121

Q8IY95
RAYQYLRPGSSYALR

SOWAHA

421

Q2M3V2
RSNDYFVLQRRRGYG

TBC1D8B

21

Q0IIM8
GISALRRVLTAYAYR

TBC1D8B

551

Q0IIM8
TGRQINDYLRRQTYG

SERPINA11

176

Q86U17
FRLRFRQFRYQEAAG

ZSCAN25

41

Q6NSZ9
YLRRIVGSATRYLQV

SLC7A7

471

Q9UM01
VYSRIPNLSRRFQYR

PHEX

371

P78562
YFHRTFVYSLLNRGR

SRD5A2

91

P31213
ALAAYSYFRINRRTI

STAB2

2476

Q8WWQ8
LDGARFRYLNEQLYS

RRP8

246

O43159
QQGLASYDYVRRRLT

PLEC

3771

Q15149
IYFIRSINAYRATLG

TTC23L

321

Q6PF05
LYNSQLLFRSRLYGD

nan

311

Q6ZUG5
RGRAYFYALLNVLSI

SLC35G6

101

P0C7Q6
LNLRQFGPYRLNYSR

WDR46

191

O15213
RRAQQIAQLYGRLYS

STARD7

36

Q9NQZ5
IAQLYGRLYSESSRR

STARD7

41

Q9NQZ5
GRSRGAIISQYYNRT

TMC6

91

Q7Z403
ALIRQNGIRRLGYTY

TEX26

46

Q8N6G2
YRLQLAQESARRYGS

WSCD2

216

Q2TBF2
LFNSTLLYRRSSYRQ

TTLL4

111

Q14679
YDQQSRRSRGFAFVY

TRA2B

151

P62995