Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	NSD1 ZNF431 CPHXL ZNF85 FOXN3 ZNF486 ZNF100 ZNF274 ZNF296 THRAP3	4.46e-05	1271	35	10	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NSD1 ZNF431 CPHXL ZNF85 ZNF486 ZNF100 ZNF274 ZNF296 THRAP3	2.21e-04	1244	35	9	GO:0000978
GeneOntologyMolecularFunction	co-receptor binding	BMP2 BMP4	2.30e-04	13	35	2	GO:0039706
GeneOntologyMolecularFunction	BMP receptor binding	BMP2 BMP4	2.30e-04	13	35	2	GO:0070700
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NSD1 ZNF431 CPHXL ZNF85 ZNF486 ZNF100 ZNF274 ZNF296 THRAP3	7.18e-04	1459	35	9	GO:0000977
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase binding	BMP2 BMP4	1.02e-03	27	35	2	GO:0070696
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	NSD1 THRAP3	1.62e-03	34	35	2	GO:0046966
GeneOntologyMolecularFunction	receptor serine/threonine kinase binding	BMP2 BMP4	1.71e-03	35	35	2	GO:0033612
GeneOntologyBiologicalProcess	regulation of odontogenesis	APC BMP2 BMP4	8.09e-06	24	34	3	GO:0042481
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	NSD1 BMP2 BMP4 ZNF431 ZNF85 FOXN3 ZNF274 BRCA1 ZNF296 ZC3H6 CDY1	8.97e-06	1399	34	11	GO:0045892
GeneOntologyBiologicalProcess	forebrain regionalization	BMP2 BMP4 PGAP1	9.18e-06	25	34	3	GO:0021871
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	NSD1 BMP2 BMP4 ZNF431 ZNF85 FOXN3 ZNF274 BRCA1 ZNF296 ZC3H6 CDY1	9.86e-06	1413	34	11	GO:1902679
GeneOntologyBiologicalProcess	cardiac jelly development	BMP2 BMP4	3.94e-05	6	34	2	GO:1905072
GeneOntologyBiologicalProcess	endocardial cushion morphogenesis	APC BMP2 BMP4	5.17e-05	44	34	3	GO:0003203
GeneOntologyBiologicalProcess	positive regulation of odontoblast differentiation	BMP2 BMP4	5.51e-05	7	34	2	GO:1901331
GeneOntologyBiologicalProcess	heart induction	BMP2 BMP4	7.34e-05	8	34	2	GO:0003129
GeneOntologyBiologicalProcess	positive regulation of neuroepithelial cell differentiation	BMP2 BMP4	7.34e-05	8	34	2	GO:1902913
GeneOntologyBiologicalProcess	regulation of heart morphogenesis	BMP2 BMP4	9.43e-05	9	34	2	GO:2000826
GeneOntologyBiologicalProcess	ameloblast differentiation	BMP2 BMP4	9.43e-05	9	34	2	GO:0036305
GeneOntologyBiologicalProcess	odontogenesis	APC SOSTDC1 BMP2 BMP4	1.08e-04	151	34	4	GO:0042476
GeneOntologyBiologicalProcess	endocardial cushion development	APC BMP2 BMP4	1.19e-04	58	34	3	GO:0003197
GeneOntologyBiologicalProcess	regulation of odontoblast differentiation	BMP2 BMP4	1.44e-04	11	34	2	GO:1901329
GeneOntologyBiologicalProcess	mesenchyme morphogenesis	APC BMP2 BMP4	1.67e-04	65	34	3	GO:0072132
GeneOntologyBiologicalProcess	lung vasculature development	BMP2 BMP4	1.72e-04	12	34	2	GO:0060426
GeneOntologyBiologicalProcess	regulation of odontogenesis of dentin-containing tooth	BMP2 BMP4	2.73e-04	15	34	2	GO:0042487
GeneOntologyBiologicalProcess	heart valve development	APC BMP2 BMP4	2.86e-04	78	34	3	GO:0003170
GeneOntologyBiologicalProcess	telencephalon regionalization	BMP2 BMP4	3.12e-04	16	34	2	GO:0021978
GeneOntologyBiologicalProcess	heart field specification	BMP2 BMP4	3.53e-04	17	34	2	GO:0003128
GeneOntologyBiologicalProcess	morphogenesis of an epithelial bud	SOSTDC1 BMP4	3.97e-04	18	34	2	GO:0060572
GeneOntologyBiologicalProcess	odontoblast differentiation	BMP2 BMP4	4.43e-04	19	34	2	GO:0071895
GeneOntologyBiologicalProcess	craniofacial suture morphogenesis	BMP4 FOXN3	4.92e-04	20	34	2	GO:0097094
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	APC BMP2 BMP4 PGAP1	7.02e-04	247	34	4	GO:0009952
GeneOntologyBiologicalProcess	dorsal/ventral pattern formation	APC SOSTDC1 BMP4	7.23e-04	107	34	3	GO:0009953
GeneOntologyBiologicalProcess	odontogenesis of dentin-containing tooth	SOSTDC1 BMP2 BMP4	7.23e-04	107	34	3	GO:0042475
GeneOntologyBiologicalProcess	cell proliferation involved in kidney development	BMP2 BMP4	7.73e-04	25	34	2	GO:0072111
GeneOntologyBiologicalProcess	regulation of cardiac muscle cell differentiation	BMP2 BMP4	7.73e-04	25	34	2	GO:2000725
GeneOntologyBiologicalProcess	regulation of animal organ morphogenesis	APC BMP2 BMP4	7.83e-04	110	34	3	GO:2000027
GeneOntologyBiologicalProcess	regulation of cell cycle	MEAF6 APC BMP2 BMP4 FOXN3 ZNF274 BRCA1 CDKL1	8.09e-04	1256	34	8	GO:0051726
GeneOntologyBiologicalProcess	organ induction	BMP2 BMP4	8.36e-04	26	34	2	GO:0001759
GeneOntologyBiologicalProcess	axis specification	APC BMP4 PGAP1	8.47e-04	113	34	3	GO:0009798
GeneOntologyBiologicalProcess	negative regulation of cell cycle	APC BMP2 BMP4 FOXN3 BRCA1	9.16e-04	464	34	5	GO:0045786
GeneOntologyBiologicalProcess	morphogenesis of an epithelial fold	SOSTDC1 BMP4	1.04e-03	29	34	2	GO:0060571
GeneOntologyBiologicalProcess	regionalization	APC SOSTDC1 BMP2 BMP4 PGAP1	1.05e-03	478	34	5	GO:0003002
GeneOntologyBiologicalProcess	negative regulation of mitotic cell cycle	APC BMP4 FOXN3 BRCA1	1.15e-03	282	34	4	GO:0045930
GeneOntologyBiologicalProcess	regulation of animal organ formation	BMP2 BMP4	1.27e-03	32	34	2	GO:0003156
GeneOntologyBiologicalProcess	endocardial cushion formation	BMP2 BMP4	1.27e-03	32	34	2	GO:0003272
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	NSD1 BMP2 BMP4 ZNF431 ZNF85 ZNF274 ZNF296	1.42e-03	1053	34	7	GO:0000122
GeneOntologyBiologicalProcess	negative regulation of myoblast differentiation	SOSTDC1 BMP4	1.43e-03	34	34	2	GO:0045662
GeneOntologyBiologicalProcess	positive regulation of p38MAPK cascade	BMP2 BMP4	1.52e-03	35	34	2	GO:1900745
GeneOntologyBiologicalProcess	pattern specification process	APC SOSTDC1 BMP2 BMP4 PGAP1	1.60e-03	526	34	5	GO:0007389
GeneOntologyBiologicalProcess	positive regulation of cartilage development	BMP2 BMP4	1.60e-03	36	34	2	GO:0061036
GeneOntologyBiologicalProcess	heart formation	BMP2 BMP4	1.60e-03	36	34	2	GO:0060914
GeneOntologyBiologicalProcess	regulation of cardiocyte differentiation	BMP2 BMP4	1.69e-03	37	34	2	GO:1905207
GeneOntologyBiologicalProcess	mitotic G2 DNA damage checkpoint signaling	FOXN3 BRCA1	1.98e-03	40	34	2	GO:0007095
GeneOntologyBiologicalProcess	cardiac epithelial to mesenchymal transition	BMP2 BMP4	1.98e-03	40	34	2	GO:0060317
GeneOntologyBiologicalProcess	negative regulation of canonical Wnt signaling pathway	APC SOSTDC1 BMP2	2.06e-03	154	34	3	GO:0090090
GeneOntologyBiologicalProcess	positive regulation of animal organ morphogenesis	BMP2 BMP4	2.08e-03	41	34	2	GO:0110110
GeneOntologyBiologicalProcess	developmental induction	BMP2 BMP4	2.08e-03	41	34	2	GO:0031128
GeneOntologyBiologicalProcess	specification of animal organ identity	BMP2 BMP4	2.08e-03	41	34	2	GO:0010092
GeneOntologyBiologicalProcess	muscle hypertrophy in response to stress	BMP2 BMP4	2.18e-03	42	34	2	GO:0003299
GeneOntologyBiologicalProcess	cardiac muscle hypertrophy in response to stress	BMP2 BMP4	2.18e-03	42	34	2	GO:0014898
GeneOntologyBiologicalProcess	cell fate commitment	APC SOSTDC1 BMP2 BMP4	2.23e-03	338	34	4	GO:0045165
GeneOntologyBiologicalProcess	positive regulation of SMAD protein signal transduction	BMP2 BMP4	2.28e-03	43	34	2	GO:0060391
GeneOntologyBiologicalProcess	cardiac muscle adaptation	BMP2 BMP4	2.28e-03	43	34	2	GO:0014887
HumanPheno	Narrow palate	NSD1 APC GTF2E2 BRCA1 PCLO	2.00e-05	202	10	5	HP:0000189
HumanPheno	Toe syndactyly	NSD1 APC BMP2 BMP4 BRCA1	5.01e-05	244	10	5	HP:0001770
MousePheno	abnormal foregut morphology	APC BMP4 PGAP1	1.34e-05	30	22	3	MP:0000474
MousePheno	decreased survivor rate	BMP2 BRCA1 SRRM4 PCLO PGAP1	1.75e-05	215	22	5	MP:0008770
MousePheno	lethality, incomplete penetrance	BMP2 BRCA1 SRRM4 PCLO PGAP1	4.19e-05	258	22	5	MP:0010831
MousePheno	absent Rathke's pouch	BMP4 PGAP1	6.58e-05	8	22	2	MP:0011759
MousePheno	mammary gland hyperplasia	APC BRCA1	8.46e-05	9	22	2	MP:0000630
MousePheno	abnormal head development	APC BMP4 PGAP1	1.20e-04	62	22	3	MP:0012176
MousePheno	abnormal mandible morphology	APC SOSTDC1 FOXN3 PGAP1	1.49e-04	176	22	4	MP:0000458
MousePheno	abnormal prenatal body size	APC BMP2 BMP4 ELOA2 ZNF274 BRCA1 ZNF296 PGAP1	1.86e-04	1116	22	8	MP:0010866
MousePheno	abnormal mesoderm development	NSD1 APC BMP4	2.04e-04	74	22	3	MP:0001680
MousePheno	abnormal developmental patterning	NSD1 APC BMP2 BMP4 ELOA2 BRCA1	2.04e-04	577	22	6	MP:0002084
MousePheno	abnormal digestive system development	APC BMP4 PGAP1	2.12e-04	75	22	3	MP:0003119
MousePheno	abnormal mesendoderm development	NSD1 APC	2.13e-04	14	22	2	MP:0009266
MousePheno	abnormal neural tube morphology	APC BMP2 BMP4 ELOA2 BRCA1 PGAP1	2.32e-04	591	22	6	MP:0002151
MousePheno	abnormal viscerocranium morphology	APC SOSTDC1 BMP4 FOXN3 PGAP1 AGAP1	2.37e-04	593	22	6	MP:0005274
MousePheno	abnormal primitive streak morphology	NSD1 APC BMP4 BRCA1	2.48e-04	201	22	4	MP:0002231
MousePheno	delayed hepatic development	BMP4 ELOA2	2.80e-04	16	22	2	MP:0000597
MousePheno	absent mandible	APC PGAP1	3.17e-04	17	22	2	MP:0000087
MousePheno	abnormal digestive system morphology	APC SOSTDC1 BMP4 MLLT6 FOXN3 SLC13A4 BRCA1 PGAP1	3.71e-04	1233	22	8	MP:0000462
MousePheno	abnormal egg cylinder morphology	NSD1 APC BRCA1	4.13e-04	94	22	3	MP:0003085
MousePheno	decreased embryo size	APC BMP2 ELOA2 ZNF274 BRCA1 ZNF296	4.18e-04	659	22	6	MP:0001698
MousePheno	abnormal nervous system development	APC BMP2 BMP4 ELOA2 BRCA1 MYCBP2 SRRM4 PGAP1	4.24e-04	1257	22	8	MP:0003861
MousePheno	abnormal gland development	APC BMP4 BRCA1 PGAP1	4.34e-04	233	22	4	MP:0020973
MousePheno	abnormal embryo size	APC BMP2 BMP4 ELOA2 ZNF274 BRCA1 ZNF296	4.69e-04	956	22	7	MP:0001697
MousePheno	anophthalmia	BMP4 ELOA2 MYCBP2 PGAP1	5.33e-04	246	22	4	MP:0001293
MousePheno	abnormal vestibular hair cell stereociliary bundle morphology	BMP4 SRRM4	5.36e-04	22	22	2	MP:0004515
MousePheno	abnormal embryo turning	APC BMP2 BMP4 ELOA2	5.75e-04	251	22	4	MP:0001700
MousePheno	embryonic lethality during organogenesis, complete penetrance	NSD1 APC BMP4 ELOA2 ZNF274 BRCA1	5.77e-04	700	22	6	MP:0011098
MousePheno	abnormal gastrulation	NSD1 APC BMP2 BMP4 ELOA2	6.83e-04	469	22	5	MP:0001695
MousePheno	abnormal phrenic nerve morphology	MYCBP2 SRRM4	6.94e-04	25	22	2	MP:0001078
MousePheno	small mandible	SOSTDC1 FOXN3 PGAP1	7.64e-04	116	22	3	MP:0004592
MousePheno	abnormal eye development	SOSTDC1 BMP4 SLC13A4 PGAP1 AGAP1	7.73e-04	482	22	5	MP:0001286
MousePheno	abnormal primitive node morphology	NSD1 APC BMP4	7.84e-04	117	22	3	MP:0004066
MousePheno	agnathia	APC PGAP1	8.10e-04	27	22	2	MP:0030268
MousePheno	prenatal lethality, incomplete penetrance	APC BMP4 FOXN3 BRCA1 ZNF296 PGAP1	8.14e-04	747	22	6	MP:0011101
MousePheno	decreased primordial germ cell number	BMP4 ZNF296	9.36e-04	29	22	2	MP:0008392
MousePheno	perinatal lethality, incomplete penetrance	SOSTDC1 BMP4 ZNF274 SRRM4 PGAP1	9.37e-04	503	22	5	MP:0011090
MousePheno	abnormal mesoderm morphology	NSD1 BMP4 BRCA1	9.94e-04	127	22	3	MP:0014141
MousePheno	abnormal rostral-caudal axis patterning	NSD1 APC BMP4	1.11e-03	132	22	3	MP:0005221
MousePheno	abnormal axial skeleton morphology	APC SOSTDC1 BMP2 BMP4 FOXN3 SLC13A4 PGAP1 AGAP1	1.15e-03	1458	22	8	MP:0002114
MousePheno	abnormal jaw morphology	APC SOSTDC1 FOXN3 PGAP1 AGAP1	1.18e-03	530	22	5	MP:0000454
MousePheno	abnormal embryonic tissue morphology	NSD1 APC BMP2 BMP4 ELOA2 BRCA1 PGAP1	1.19e-03	1116	22	7	MP:0002085
MousePheno	abnormal primordial germ cell morphology	BMP4 ZNF296	1.21e-03	33	22	2	MP:0008391
MousePheno	abnormal head morphology	APC SOSTDC1 BMP4 FOXN3 SLC13A4 PGAP1 AGAP1	1.21e-03	1120	22	7	MP:0000432
MousePheno	lethality during fetal growth through weaning, incomplete penetrance	APC SOSTDC1 BMP4 FOXN3 ZNF274 SRRM4 PGAP1	1.24e-03	1124	22	7	MP:0011112
MousePheno	abnormal cranium morphology	APC SOSTDC1 BMP4 FOXN3 PGAP1 AGAP1	1.27e-03	813	22	6	MP:0000438
MousePheno	perinatal lethality	APC SOSTDC1 BMP4 ZNF274 MYCBP2 SRRM4 PGAP1	1.28e-03	1130	22	7	MP:0002081
MousePheno	abnormal basioccipital bone morphology	FOXN3 PGAP1	1.29e-03	34	22	2	MP:0000079
MousePheno	abnormal embryonic-extraembryonic boundary morphology	APC BRCA1	1.29e-03	34	22	2	MP:0003890
MousePheno	abnormal prenatal growth/weight/body size	APC BMP2 BMP4 ELOA2 ZNF274 BRCA1 ZNF296 PGAP1	1.34e-03	1493	22	8	MP:0004196
MousePheno	abnormal craniofacial bone morphology	APC SOSTDC1 BMP4 FOXN3 PGAP1 AGAP1	1.39e-03	827	22	6	MP:0002116
MousePheno	digestive/alimentary phenotype	APC SOSTDC1 BMP4 MLLT6 FOXN3 SLC13A4 BRCA1 PGAP1	1.39e-03	1500	22	8	MP:0005381
MousePheno	abnormal germ layer development	NSD1 APC BMP4	1.43e-03	144	22	3	MP:0001674
MousePheno	abnormal pituitary diverticulum morphology	BMP4 PGAP1	1.44e-03	36	22	2	MP:0003817
MousePheno	increased mammary gland tumor incidence	APC BRCA1	1.61e-03	38	22	2	MP:0010299
MousePheno	abnormal adenohypophysis development	BMP4 PGAP1	1.61e-03	38	22	2	MP:0013337
MousePheno	embryonic lethality during organogenesis	NSD1 APC BMP4 ELOA2 ZNF274 BRCA1	1.86e-03	876	22	6	MP:0006207
MousePheno	abnormal female reproductive system physiology	APC BMP2 BMP4 BRCA1 ZNF296 BRWD1	1.86e-03	876	22	6	MP:0003699
MousePheno	abnormal pituitary gland development	BMP4 PGAP1	1.96e-03	42	22	2	MP:0003816
MousePheno	small gonad	APC BMP4 ZNF274 BRCA1 ZNF296 BRWD1	1.96e-03	885	22	6	MP:0001116
MousePheno	abnormal germ layer morphology	NSD1 BMP4 BRCA1	1.97e-03	161	22	3	MP:0014138
MousePheno	abnormal primary sex determination	APC BMP4 ZNF274 BRCA1 ZNF296 BRWD1	2.15e-03	901	22	6	MP:0002211
MousePheno	abnormal axon guidance	MYCBP2 SRRM4	2.25e-03	45	22	2	MP:0002961
MousePheno	abnormal facial morphology	SOSTDC1 BMP4 FOXN3 SLC13A4 PGAP1 AGAP1	2.26e-03	910	22	6	MP:0003743
MousePheno	abnormal heart development	APC BMP2 BMP4 BRCA1	2.47e-03	372	22	4	MP:0000267
MousePheno	abnormal vestibular hair cell morphology	BMP4 SRRM4	2.55e-03	48	22	2	MP:0002623
MousePheno	absent facial bone	APC PGAP1	2.66e-03	49	22	2	MP:0030385
MousePheno	abnormal brain development	APC BMP4 ELOA2 BRCA1 PGAP1	2.69e-03	638	22	5	MP:0000913
MousePheno	abnormal sex determination	APC BMP4 ZNF274 BRCA1 ZNF296 BRWD1	2.74e-03	945	22	6	MP:0002210
MousePheno	abnormal embryonic growth/weight/body size	APC BMP2 BMP4 ELOA2 ZNF274 BRCA1 ZNF296	2.82e-03	1295	22	7	MP:0002088
MousePheno	abnormal endoderm development	NSD1 APC	3.22e-03	54	22	2	MP:0001685
MousePheno	abnormal iris morphology	BMP4 SLC13A4 AGAP1	3.24e-03	192	22	3	MP:0001322
MousePheno	abnormal innervation	BMP4 MYCBP2 SRRM4	3.29e-03	193	22	3	MP:0002184
MousePheno	prenatal lethality prior to heart atrial septation, incomplete penetrance	APC BMP4 FOXN3 ZNF296	3.51e-03	410	22	4	MP:0031660
MousePheno	embryonic lethality, incomplete penetrance	APC BMP4 FOXN3 ZNF296	3.51e-03	410	22	4	MP:0011102
MousePheno	decreased rib number	BMP2 BMP4	3.58e-03	57	22	2	MP:0003345
MousePheno	abnormal anterior uvea morphology	BMP4 SLC13A4 AGAP1	3.58e-03	199	22	3	MP:0005194
MousePheno	abnormal liver development	BMP4 ELOA2	3.71e-03	58	22	2	MP:0000596
MousePheno	abnormal semicircular canal morphology	BMP4 SRRM4	3.83e-03	59	22	2	MP:0002428
MousePheno	abnormal embryo development	NSD1 APC BMP2 BMP4 ELOA2 BRCA1 ZNF296	3.89e-03	1370	22	7	MP:0001672
MousePheno	craniofacial phenotype	APC SOSTDC1 BMP4 FOXN3 SLC13A4 PGAP1 AGAP1	3.92e-03	1372	22	7	MP:0005382
MousePheno	abnormal craniofacial morphology	APC SOSTDC1 BMP4 FOXN3 SLC13A4 PGAP1 AGAP1	3.92e-03	1372	22	7	MP:0000428
Domain	KRAB	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274	3.84e-04	358	33	5	PS50805
Domain	KRAB	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274	3.84e-04	358	33	5	PF01352
Domain	KRAB	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274	4.41e-04	369	33	5	SM00349
Domain	KRAB	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274	4.46e-04	370	33	5	IPR001909
Domain	-	NSD1 MLLT6 BRCA1 MYCBP2 PCLO	1.07e-03	449	33	5	3.30.40.10
Domain	-	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	1.08e-03	679	33	6	3.30.160.60
Domain	TGFb_propeptide	BMP2 BMP4	1.11e-03	28	33	2	PF00688
Domain	TGF-b_N	BMP2 BMP4	1.11e-03	28	33	2	IPR001111
Domain	Znf_RING/FYVE/PHD	NSD1 MLLT6 BRCA1 MYCBP2 PCLO	1.18e-03	459	33	5	IPR013083
Domain	zf-C2H2	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	1.20e-03	693	33	6	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	1.21e-03	694	33	6	IPR013087
Domain	TGF-beta-rel	BMP2 BMP4	1.45e-03	32	33	2	IPR015615
Domain	TGFb_CS	BMP2 BMP4	1.45e-03	32	33	2	IPR017948
Domain	TGFB	BMP2 BMP4	1.94e-03	37	33	2	SM00204
Domain	TGF_BETA_2	BMP2 BMP4	1.94e-03	37	33	2	PS51362
Domain	TGF_beta	BMP2 BMP4	1.94e-03	37	33	2	PF00019
Domain	TGF-b_C	BMP2 BMP4	1.94e-03	37	33	2	IPR001839
Domain	TGF_BETA_1	BMP2 BMP4	1.94e-03	37	33	2	PS00250
Domain	ZINC_FINGER_C2H2_2	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	2.12e-03	775	33	6	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	2.15e-03	777	33	6	PS00028
Domain	zf-C2H2_6	ZNF431 ZNF85 ZNF486 ZNF100	2.18e-03	314	33	4	PF13912
Domain	Znf_FYVE_PHD	NSD1 MLLT6 PCLO	2.19e-03	147	33	3	IPR011011
Domain	Znf_C2H2-like	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	2.43e-03	796	33	6	IPR015880
Domain	Znf_C2H2	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	2.57e-03	805	33	6	IPR007087
Domain	ZnF_C2H2	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	2.62e-03	808	33	6	SM00355
Domain	Zinc_finger_PHD-type_CS	NSD1 MLLT6	5.87e-03	65	33	2	IPR019786
Domain	-	BMP2 BMP4	6.23e-03	67	33	2	2.10.90.10
Domain	Cystine-knot_cytokine	BMP2 BMP4	6.23e-03	67	33	2	IPR029034
Domain	PHD	NSD1 MLLT6	7.75e-03	75	33	2	PF00628
Domain	Znf_PHD-finger	NSD1 MLLT6	8.57e-03	79	33	2	IPR019787
Domain	PHD	NSD1 MLLT6	1.08e-02	89	33	2	SM00249
Domain	Znf_PHD	NSD1 MLLT6	1.12e-02	91	33	2	IPR001965
Domain	ZF_PHD_2	NSD1 MLLT6	1.22e-02	95	33	2	PS50016
Domain	ZF_PHD_1	NSD1 MLLT6	1.24e-02	96	33	2	PS01359
Domain	RING	NSD1 BRCA1 MYCBP2	1.64e-02	305	33	3	SM00184
Pathway	BIOCARTA_ALK_PATHWAY	APC BMP2 BMP4	4.15e-05	37	26	3	M17400
Pathway	PID_BMP_PATHWAY	SOSTDC1 BMP2 BMP4	6.10e-05	42	26	3	M181
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	MEAF6 BMP2 ZNF431 LUZP4 GTF2E2 ELOA2 ZNF486 ZNF100 ZNF274 BRCA1	9.99e-05	1387	26	10	M734
Pathway	KEGG_BASAL_CELL_CARCINOMA	APC BMP2 BMP4	1.37e-04	55	26	3	M17807
Pathway	KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST	BMP2 BMP4	3.38e-04	15	26	2	M47824
Pathway	KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY	BMP2 BMP4	6.09e-04	20	26	2	M47843
Pathway	WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE	BMP2 BMP4	9.56e-04	25	26	2	M39665
Pathway	WP_FGFR3_SIGNALING_IN_CHONDROCYTE_PROLIFERATION_AND_TERMINAL_DIFFERENTIATION	BMP2 BMP4	1.12e-03	27	26	2	M39838
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY	BMP2 BMP4	1.29e-03	29	26	2	M47372
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY	BMP2 BMP4	1.29e-03	29	26	2	M47377
Pathway	WP_OLIGODENDROCYTE_SPECIFICATION_AND_DIFFERENTIATION_LEADING_TO_MYELIN_COMPONENTS_FOR_CNS	BMP2 BMP4	1.38e-03	30	26	2	M39775
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	BMP2 BMP4	1.57e-03	32	26	2	MM14854
Pubmed	Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot.	SOSTDC1 BMP2 BMP4	1.02e-08	5	36	3	14623234
Pubmed	Foxn3 is essential for craniofacial development in mice and a putative candidate involved in human congenital craniofacial defects.	BMP2 BMP4 FOXN3	1.02e-08	5	36	3	20691664
Pubmed	USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney.	SOSTDC1 BMP2 BMP4	1.02e-08	5	36	3	15020244
Pubmed	Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse.	SOSTDC1 BMP2 BMP4	2.89e-07	13	36	3	18329379
Pubmed	Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice.	SOSTDC1 BMP2 BMP4	3.68e-07	14	36	3	18483623
Pubmed	Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms.	SOSTDC1 BMP2 BMP4	4.59e-07	15	36	3	30235284
Pubmed	Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation.	SOSTDC1 BMP2 BMP4	5.65e-07	16	36	3	18256193
Pubmed	Divergent and Compensatory Effects of BMP2 and BMP4 on the VSMC Phenotype and BMP4's Role in Thoracic Aortic Aneurysm Development.	BMP2 BMP4	1.04e-06	2	36	2	38727271
Pubmed	Cross-talk between fibroblast growth factor and bone morphogenetic proteins regulates gap junction-mediated intercellular communication in lens cells.	BMP2 BMP4	1.04e-06	2	36	2	18400943
Pubmed	Phenotype characterization and sequence analysis of BMP2 and BMP4 variants in two Mexican families with oligodontia.	BMP2 BMP4	1.04e-06	2	36	2	23079991
Pubmed	Double mutation of APC and BRCA1 in an Italian family.	APC BRCA1	1.04e-06	2	36	2	32388397
Pubmed	Methylation Analysis of BRCA1 and APC in Breast Cancer and It's Relationship to Clinicopathological Features.	APC BRCA1	1.04e-06	2	36	2	28164568
Pubmed	Epithelial Bone Morphogenic Protein 2 and 4 Are Indispensable for Tooth Development.	BMP2 BMP4	1.04e-06	2	36	2	34483952
Pubmed	Rare variants in BMP2 and BMP4 found in otosclerosis patients reduce Smad signaling.	BMP2 BMP4	1.04e-06	2	36	2	24492129
Pubmed	Polymorphisms in BMP2/BMP4, with estimates of mean lung dose, predict radiation pneumonitis among patients receiving definitive radiotherapy for non-small cell lung cancer.	BMP2 BMP4	1.04e-06	2	36	2	28574846
Pubmed	BMP2/BMP4 colorectal cancer susceptibility loci in northern and southern European populations.	BMP2 BMP4	1.04e-06	2	36	2	23161572
Pubmed	Bone morphogenetic proteins 2 and 4 are selectively expressed by late outgrowth endothelial progenitor cells and promote neoangiogenesis.	BMP2 BMP4	1.04e-06	2	36	2	18818419
Pubmed	BMP2 and BMP4 variations and risk of non-syndromic cleft lip and palate.	BMP2 BMP4	1.04e-06	2	36	2	27591802
Pubmed	Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling.	BMP2 BMP4	1.04e-06	2	36	2	18628975
Pubmed	Abrogation of epithelial BMP2 and BMP4 causes Amelogenesis Imperfecta by reducing MMP20 and KLK4 expression.	BMP2 BMP4	1.04e-06	2	36	2	27146352
Pubmed	Inhibition of BMP2 and BMP4 Represses Barrett's Esophagus While Enhancing the Regeneration of Squamous Epithelium in Preclinical Models.	BMP2 BMP4	1.04e-06	2	36	2	36706916
Pubmed	Titanium With Nanotopography Induces Osteoblast Differentiation by Regulating Endogenous Bone Morphogenetic Protein Expression and Signaling Pathway.	BMP2 BMP4	1.04e-06	2	36	2	26681207
Pubmed	Association of bone morphogenetic proteins with otosclerosis.	BMP2 BMP4	1.04e-06	2	36	2	18021008
Pubmed	Cloning of rat type I receptor cDNA for bone morphogenetic protein-2 and bone morphogenetic protein-4, and the localization compared with that of the ligands.	BMP2 BMP4	1.04e-06	2	36	2	8896987
Pubmed	Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer.	BMP2 BMP4	1.04e-06	2	36	2	19799789
Pubmed	BMP-2 induced Dspp transcription is mediated by Dlx3/Osx signaling pathway in odontoblasts.	BMP2 BMP4	1.04e-06	2	36	2	28883412
Pubmed	Bone morphogenetic protein signaling is involved in human mesenchymal stem cell survival in serum-free medium.	BMP2 BMP4	1.04e-06	2	36	2	19473100
Pubmed	BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization.	BMP2 BMP4	1.04e-06	2	36	2	19021035
Pubmed	Lack of effect of bone morphogenetic protein 2 and 4 gene polymorphisms on bone density in postmenopausal Turkish women.	BMP2 BMP4	1.04e-06	2	36	2	21128211
Pubmed	Genetic variation in bone morphogenetic proteins family members (BMPs 2 and 4) and hypertension risk in middle-aged men: The TAMRISK study.	BMP2 BMP4	1.04e-06	2	36	2	29390526
Pubmed	Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis.	BMP2 BMP4	1.04e-06	2	36	2	24648278
Pubmed	Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension.	BMP2 BMP4	1.04e-06	2	36	2	20042692
Pubmed	The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development.	BMP2 BMP4	1.04e-06	2	36	2	8413626
Pubmed	[Correlation of BRCA1 and APC aberrant methylation with the response to anthracycline-based neoadjuvant chemotherapy in primary breast cancer].	APC BRCA1	1.04e-06	2	36	2	19615284
Pubmed	Heparan sulfate acts as a bone morphogenetic protein coreceptor by facilitating ligand-induced receptor hetero-oligomerization.	BMP2 BMP4	1.04e-06	2	36	2	20861306
Pubmed	Bone morphogenetic protein-2 and -4 expression during murine orofacial development.	BMP2 BMP4	1.04e-06	2	36	2	8651889
Pubmed	Establishment of Immortalized BMP2/4 Double Knock-Out Osteoblastic Cells Is Essential for Study of Osteoblast Growth, Differentiation, and Osteogenesis.	BMP2 BMP4	1.04e-06	2	36	2	26595646
Pubmed	Bmp2 and Bmp4 accelerate alveolar bone development.	BMP2 BMP4	1.04e-06	2	36	2	25491151
Pubmed	Persistent Wnt/β-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme.	SOSTDC1 BMP2 BMP4	1.15e-06	20	36	3	30570432
Pubmed	Serum Levels of Bone Morphogenetic Proteins 2 and 4 in Patients with Acute Myocardial Infarction.	BMP2 BMP4	3.12e-06	3	36	2	32992577
Pubmed	Rudiment incisors survive and erupt as supernumerary teeth as a result of USAG-1 abrogation.	SOSTDC1 BMP4	3.12e-06	3	36	2	17555714
Pubmed	The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4.	BMP2 BMP4	3.12e-06	3	36	2	8752214
Pubmed	Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells.	BMP2 BMP4	3.12e-06	3	36	2	28747434
Pubmed	BMP signaling is required for adult skeletal homeostasis and mediates bone anabolic action of parathyroid hormone.	BMP2 BMP4	3.12e-06	3	36	2	27567726
Pubmed	Bone morphogenetic protein (BMP)-7 but not BMP-2 and BMP-4 improves maintenance of primitive peripheral blood-derived hematopoietic progenitor cells (HPC) cultured in serum-free medium supplemented with early acting cytokines.	BMP2 BMP4	3.12e-06	3	36	2	18029192
Pubmed	Bone Morphogenetic Protein 2 Coordinates Early Tooth Mineralization.	BMP2 BMP4	3.12e-06	3	36	2	29489425
Pubmed	Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α.	BMP2 BMP4	3.12e-06	3	36	2	21888945
Pubmed	Single-nucleotide polymorphisms and haplotypes of bone morphogenetic protein genes and peripheral bone mineral density in young Korean men and women.	BMP2 BMP4	3.12e-06	3	36	2	16604289
Pubmed	Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7.	BMP2 BMP4	3.12e-06	3	36	2	25378054
Pubmed	Cooperation of endoderm-derived BMP2 and extraembryonic ectoderm-derived BMP4 in primordial germ cell generation in the mouse.	BMP2 BMP4	3.12e-06	3	36	2	11401407
Pubmed	Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development.	BMP2 BMP4	3.12e-06	3	36	2	7799920
Pubmed	Noggin is a negative regulator of neuronal differentiation in developing neocortex.	BMP2 BMP4	3.12e-06	3	36	2	10657699
Pubmed	Apoptosis induction and reduced proliferation in human osteoblasts by rhBMP-2, -4 and -7.	BMP2 BMP4	3.12e-06	3	36	2	19240369
Pubmed	Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.	BMP2 BMP4	3.12e-06	3	36	2	21655089
Pubmed	Regulation of bone morphogenetic protein signalling in human pulmonary vascular development.	BMP2 BMP4	3.12e-06	3	36	2	17992660
Pubmed	Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation.	BMP2 BMP4	3.12e-06	3	36	2	15039429
Pubmed	Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with chronic degeneration of the rotator cuff.	BMP2 BMP4	3.12e-06	3	36	2	16719933
Pubmed	Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart.	BMP2 BMP4	3.12e-06	3	36	2	11512673
Pubmed	Dynamics and cellular localization of Bmp2, Bmp4, and Noggin transcription in the postnatal mouse skeleton.	BMP2 BMP4	3.12e-06	3	36	2	25043193
Pubmed	BMP-2 and -4 produced by vascular smooth muscle cells from atherosclerotic lesions induce monocyte chemotaxis through direct BMPRII activation.	BMP2 BMP4	3.12e-06	3	36	2	24814649
Pubmed	Genetic variants in bone morphogenetic proteins signaling pathway might be involved in palatal rugae phenotype in humans.	BMP2 BMP4	3.12e-06	3	36	2	34135450
Pubmed	Agrin binds BMP2, BMP4 and TGFbeta1.	BMP2 BMP4	3.12e-06	3	36	2	20505824
Pubmed	Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4.	BMP2 BMP4	3.12e-06	3	36	2	17255107
Pubmed	Type II collagen accumulation in overlying dermo-epidermal junction of pilomatricoma is mediated by bone morphogenetic protein 2 and 4.	BMP2 BMP4	3.12e-06	3	36	2	15102076
Pubmed	Conditional deletion of BMP7 from the limb skeleton does not affect bone formation or fracture repair.	BMP2 BMP4	3.12e-06	3	36	2	19780203
Pubmed	Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in Apc(Min)/+ mice.	APC BRCA1	3.12e-06	3	36	2	11181458
Pubmed	Investigation of the association of BMP gene variants with nephropathy in Type 1 diabetes mellitus.	BMP2 BMP4	3.12e-06	3	36	2	20546278
Pubmed	Evaluation of the Genetic Association and mRNA Expression of the COL1A1, BMP2, and BMP4 Genes in the Development of Otosclerosis.	BMP2 BMP4	3.12e-06	3	36	2	32379989
Pubmed	Bmp signaling in molar cusp formation.	BMP2 BMP4	3.12e-06	3	36	2	30980961
Pubmed	Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression.	BMP2 BMP4	3.12e-06	3	36	2	24100446
Pubmed	The frequency of founder mutations in the BRCA1, BRCA2, and APC genes in Australian Ashkenazi Jews: implications for the generality of U.S. population data.	APC BRCA1	3.12e-06	3	36	2	11466700
Pubmed	Bone morphogenetic proteins and secreted frizzled related protein 2 maintain the quiescence of adult mammalian retinal stem cells.	BMP2 BMP4	3.12e-06	3	36	2	23843349
Pubmed	Association of bone morphogenetic proteins with spinal fusion in ankylosing spondylitis.	BMP2 BMP4	3.12e-06	3	36	2	20682677
Pubmed	Direct BMP2/4 signaling through BMP receptor IA regulates fetal thymocyte progenitor homeostasis and differentiation to CD4+CD8+ double-positive cell.	BMP2 BMP4	3.12e-06	3	36	2	24240189
Pubmed	Using EC and ES cell culture to study early development: recent observations on Indian hedgehog and Bmps.	BMP2 BMP4	3.12e-06	3	36	2	9853822
Pubmed	Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation.	BMP2 BMP4	3.12e-06	3	36	2	17003113
Pubmed	The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells.	BMP2 BMP4	3.12e-06	3	36	2	23349763
Pubmed	Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling.	APC SOSTDC1 BMP4	5.96e-06	34	36	3	23293290
Pubmed	Novel regulators of bone formation: molecular clones and activities.	BMP2 BMP4	6.24e-06	4	36	2	3201241
Pubmed	Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor.	BMP2 BMP4	6.24e-06	4	36	2	15975920
Pubmed	Skeletal abnormalities in doubly heterozygous Bmp4 and Bmp7 mice.	BMP2 BMP4	6.24e-06	4	36	2	9664686
Pubmed	A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehog expression in the mouse tooth germ.	BMP2 BMP4	6.24e-06	4	36	2	10704389
Pubmed	BMPs: time to murder and create?	BMP2 BMP4	6.24e-06	4	36	2	10204532
Pubmed	Immunohistochemical localization of bone morphogenetic proteins (BMPs) 2, 4, 6, and 7 during induced heterotopic bone formation.	BMP2 BMP4	6.24e-06	4	36	2	17262821
Pubmed	BMP signaling in the human fetal ovary is developmentally regulated and promotes primordial germ cell apoptosis.	BMP2 BMP4	6.24e-06	4	36	2	20506112
Pubmed	Pancreatic Cancer with Mutation in BRCA1/2, MLH1, and APC Genes: Phenotype Correlation and Detection of a Novel Germline BRCA2 Mutation.	APC BRCA1	6.24e-06	4	36	2	35205366
Pubmed	Alteration in the expression of bone morphogenetic protein-2,3,4,5 mRNA during pathogenesis of cleft palate in BALB/c mice.	BMP2 BMP4	6.24e-06	4	36	2	10716617
Pubmed	Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation.	BMP2 BMP4	6.24e-06	4	36	2	17244894
Pubmed	Immunoexpression of BMP-2 and BMP-4 and their receptors, BMPR-IA and BMPR-II, in ameloblastomas and adenomatoid odontogenic tumors.	BMP2 BMP4	6.24e-06	4	36	2	27780042
Pubmed	Pleiotrophin expression during odontogenesis.	BMP2 BMP4	6.24e-06	4	36	2	22382872
Pubmed	Changes in homeobox-containing gene expression during ectopic bone formation induced by bone morphogenetic protein.	BMP2 BMP4	6.24e-06	4	36	2	7911662
Pubmed	A heart-hand syndrome gene: Tfap2b plays a critical role in the development and remodeling of mouse ductus arteriosus and limb patterning.	BMP2 BMP4	6.24e-06	4	36	2	21829553
Pubmed	Comparative analysis of neural crest cell death, migration, and function during vertebrate embryogenesis.	BMP2 BMP4	6.24e-06	4	36	2	14699574
Pubmed	Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae.	BMP2 BMP4	6.24e-06	4	36	2	10330496
Pubmed	Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis.	BMP2 BMP4	6.24e-06	4	36	2	12163415
Pubmed	BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation.	BMP2 BMP4	6.24e-06	4	36	2	12897139
Pubmed	Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivo.	BMP2 BMP4	6.24e-06	4	36	2	22701694
Pubmed	Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration.	BMP2 BMP4	6.24e-06	4	36	2	18202659
Pubmed	Investigation of Genetic Polymorphisms in BMP2, BMP4, SMAD6, and RUNX2 and Persistent Apical Periodontitis.	BMP2 BMP4	6.24e-06	4	36	2	33245975
Pubmed	Regulation of human erythropoiesis by activin A, BMP2, and BMP4, members of the TGFbeta family.	BMP2 BMP4	6.24e-06	4	36	2	12531697
Cytoband	19p12	ZNF431 ZNF85 ZNF486 ZNF100	8.68e-07	90	37	4	19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF431 ZNF85 ZNF486 ZNF100	2.93e-06	122	37	4	chr19p12
Cytoband	17q21	MLLT6 BRCA1	1.20e-03	63	37	2	17q21
Cytoband	Ensembl 112 genes in cytogenetic band chr14q22	BMP4 CDKL1	2.64e-03	94	37	2	chr14q22
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP2 BMP4	7.02e-05	11	21	2	455
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF431 ZNF85 ZNF486 ZNF100 ZNF274 ZNF296	1.25e-04	718	21	6	28
GeneFamily	PHD finger proteins	NSD1 MLLT6	4.84e-03	90	21	2	88
Coexpression	HOQUE_METHYLATED_IN_CANCER	APC BMP2 BRCA1	6.27e-05	56	36	3	M19948
Coexpression	GRESHOCK_CANCER_COPY_NUMBER_UP	NSD1 APC MLLT6 BRCA1 THRAP3	7.59e-05	323	36	5	M9150
Coexpression	MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_27	NSD1 APC	8.20e-05	10	36	2	M3815
Coexpression	MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_12	MLLT6 BRCA1	1.00e-04	11	36	2	M16845
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	APC FOXN3 MYCBP2 SRRM4 PCLO PGAP1 AGAP1 BRWD1	1.03e-04	1106	36	8	M39071
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	APC R3HDM2 GTF2E2 FOXN3 BRCA1 MYCBP2 AGAP1	1.41e-04	856	36	7	M4500
Coexpression	GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_DN	MLLT6 ZNF274 ZNF296 CEP95	1.51e-04	197	36	4	M9721
Coexpression	GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP	APC MYCBP2 PGAP1 BRWD1	1.60e-04	200	36	4	M4884
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	NSD1 APC SOSTDC1 MYCBP2 CDKL1 BRWD1	3.85e-05	379	36	6	gudmap_developingKidney_e15.5_1000_k3
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|368C / Donor, Lineage, Cell class and subclass (all cells)	BMP2 ZNF274 CEP95 PCLO	1.15e-05	169	37	4	0d96c0b4fd26fbc0bf44ff7bed2936eebcc55b74
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 APC MYCBP2 THRAP3	1.61e-05	184	37	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Intermediate\|3m / Sample Type, Dataset, Time_group, and Cell type.	ERICH1 ZNF431 MYCBP2 ZC3H6	2.23e-05	200	37	4	cbd0b9188a94778ffa539912aeb2a4378f0ab88f
Disease	otosclerosis (is_implicated_in)	BMP2 BMP4	2.29e-05	6	37	2	DOID:12185 (is_implicated_in)
Disease	Marfan syndrome (implicated_via_orthology)	BMP2 BMP4	6.84e-05	10	37	2	DOID:14323 (implicated_via_orthology)
Disease	tooth agenesis (is_implicated_in)	BMP2 BMP4	6.84e-05	10	37	2	DOID:0050591 (is_implicated_in)
Disease	Benign tumor of pancreas	APC BRCA1	1.18e-04	13	37	2	C0347284
Disease	juvenile polyposis syndrome (implicated_via_orthology)	BMP2 BMP4	1.18e-04	13	37	2	DOID:0050787 (implicated_via_orthology)
Disease	Pancreatic carcinoma	APC BRCA1	2.58e-04	19	37	2	C0235974
Disease	prostate carcinoma (is_marker_for)	BMP2 BMP4	3.81e-04	23	37	2	DOID:10286 (is_marker_for)
Disease	prostate cancer (is_implicated_in)	APC BMP2 BRCA1	4.28e-04	117	37	3	DOID:10283 (is_implicated_in)
Disease	breast cancer (implicated_via_orthology)	APC BRCA1	4.51e-04	25	37	2	DOID:1612 (implicated_via_orthology)
Disease	colorectal cancer, colorectal adenoma	APC BMP2 BMP4	9.16e-04	152	37	3	EFO_0005406, MONDO_0005575
Disease	Colorectal Carcinoma	ERICH1 APC BMP2 BMP4 ELOA2	1.74e-03	702	37	5	C0009402
Disease	cup-to-disc ratio measurement	BMP2 BMP4 GTF2E2 NOL12	2.01e-03	430	37	4	EFO_0006939

Protein segments in the cluster

Peptide	Gene	Start	Entry
HDQPKRRRIRKHKSK	ERICH1	106	Q86X53
PTHHERGQKKSRKDK	MLLT6	231	P55198
KTPVTDKHHRSKNRK	CDY1	96	Q9Y6F8
SPHANRKKHRRKKST	AGAP1	521	Q9UPQ3
HKQRKRLKSSCKRHP	BMP2	286	P12643
KRSPKHHSQRARKKN	BMP4	291	P12644
HGHARKRAKSNSKLK	R3HDM2	61	Q9Y2K5
DKPRKRKRQRHAAAK	NSD1	1466	Q96L73
HSRKKVKRKHPRRAQ	NOL12	171	Q9UGY1
KKESPSRQQSKAHRH	LUZP4	56	Q9P127
KRPQHSHSNKKRPSL	ELOA2	306	Q8IYF1
SHKKGESKQQRKARH	PCLO	1746	Q9Y6V0
HNSKAPKKNRLRRKS	BRCA1	601	P38398
RKQKRRKTEQHSHPF	FAM157B	101	P0CG42
HNKPTRKTLRKSRKH	CDKL1	301	Q00532
SQHKKRQHFAKARKV	FOXN3	416	O00409
NKHKQFHLERKRQRK	CEP95	456	Q96GE4
RHTNIHKIDAPSKRK	BRWD1	2031	Q9NSI6
SSHKKRKNKNRHRID	MEAF6	166	Q9HAF1
SPRKQKLNRKYRSHH	SLC13A4	246	Q9UKG4
RQTKNKRKTKHRHKF	CPHXL	21	A0A1W2PPM1
KPASQKKRRFKTHNE	GTF2E2	261	P29084
TSKPKHRHRKAQIKT	PKDREJ	1516	Q9NTG1
RLRSHPAQLKHKRDK	MYCBP2	896	O75592
PKHSRRSEKKSNHHK	PGAP1	781	Q75T13
PKASHRSKQRHKQSL	APC	781	P25054
ANRHKTRHTGKKPFK	ZNF431	191	Q8TF32
NSNRHKIRHTRKKPF	ZNF100	191	Q8IYN0
HKGSKKQKKHRRARD	THRAP3	761	Q9Y2W1
KSKRRKREKHKHNSP	ZC3H6	61	P61129
GHQRTHNRTKRKKKQ	ZNF274	636	Q96GC6
EKRHKKQSRSRPRKS	SRRM4	166	A7MD48
KPVQHHRERKRASKS	SOSTDC1	186	Q6X4U4
SNRHEIRHTKKKPFK	ZNF85	161	Q03923
FSNSKRHKRRHTEKK	ZNF486	166	Q96H40
GKRKNKKNRRRHHAS	PNMA8C	186	A0A1B0GUJ8
SSKLNRHKKTHRQVP	ZNF296	271	Q8WUU4