Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF502 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 MEIS3 ZNF625 ZNF658B ZNF418 ZNF416 ZNF548 ZNF730 MEIS3P1 ZNF551 ZNF2 ZNF304	2.27e-31	1459	81	46	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF502 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF470 MEIS3 ZNF658B ZNF418 ZNF416 ZNF548 ZNF730 MEIS3P1 ZNF551 ZNF2 ZNF304	1.33e-30	1244	81	43	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF502 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF470 MEIS3 ZNF658B ZNF418 ZNF416 ZNF548 ZNF730 MEIS3P1 ZNF551 ZNF2 ZNF304	3.23e-30	1271	81	43	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF502 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF773 ZNF586 ZNF211 ZNF605 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 MEIS3 ZNF625 ZNF658B ZNF418 ZNF416 ZNF548 ZNF730 MEIS3P1 ZNF551 ZNF2 ZNF304	1.54e-29	1412	81	44	GO:0000981
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBN1 FBN2	1.04e-03	12	81	2	GO:0030023
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBN1 FBN2	1.43e-03	14	81	2	GO:0097493
HumanPheno	Abnormal upper to lower segment ratio	FBN1 FBN2	1.52e-05	3	12	2	HP:0012772
HumanPheno	Crumpled ear	FBN1 FBN2	7.59e-05	6	12	2	HP:0009901
HumanPheno	Bicuspid aortic valve	ZNF462 FBN1 FBN2 BAZ1B	1.21e-04	119	12	4	HP:0001647
HumanPheno	Abnormal aortic valve cusp morphology	ZNF462 FBN1 FBN2 BAZ1B	1.29e-04	121	12	4	HP:0031567
HumanPheno	Mitral valve prolapse	FBN1 FBN2 SPRED2 BAZ1B	1.38e-04	123	12	4	HP:0001634
MousePheno	increased heart left ventricle size	FBN1 ERGIC3 BAZ1B ZNF418 ZNF416	1.67e-05	134	34	5	MP:0010579
MousePheno	abnormal heart left ventricle size	FBN1 ERGIC3 BAZ1B ZNF418 ZNF416	5.10e-05	169	34	5	MP:0010578
MousePheno	enlarged chest	FBN1 CCN3	5.72e-05	5	34	2	MP:0001267
MousePheno	atrial septal defect	PCSK5 PCSK6 JAG1 BAZ1B	5.89e-05	88	34	4	MP:0010403
MousePheno	increased heart ventricle size	FBN1 ERGIC3 BAZ1B ZNF418 ZNF416	6.02e-05	175	34	5	MP:0008772
MousePheno	abnormal heart ventricle morphology	PCSK5 FBN1 ERGIC3 PCSK6 JAG1 BAZ1B ZNF418 ZNF416 CCN3	8.43e-05	793	34	9	MP:0005294
MousePheno	abnormal interatrial septum morphology	PCSK5 PCSK6 JAG1 BAZ1B	1.26e-04	107	34	4	MP:0000282
MousePheno	abnormal heart ventricle size	FBN1 ERGIC3 BAZ1B ZNF418 ZNF416	2.09e-04	228	34	5	MP:0031543
MousePheno	abnormal heart atrium morphology	PCSK5 FBN1 PCSK6 JAG1 BAZ1B	2.27e-04	232	34	5	MP:0003105
Domain	Znf_C2H2/integrase_DNA-bd	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	3.05e-42	694	79	44	IPR013087
Domain	-	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	4.02e-41	679	79	43	3.30.160.60
Domain	zf-C2H2	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	9.68e-41	693	79	43	PF00096
Domain	KRAB	ZNF132 ZNF514 ZNF17 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZNF530 ZNF658 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	1.47e-40	369	79	36	SM00349
Domain	KRAB	ZNF132 ZNF514 ZNF17 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZNF530 ZNF658 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	1.62e-40	370	79	36	IPR001909
Domain	ZINC_FINGER_C2H2_2	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	3.90e-40	775	79	44	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	4.37e-40	777	79	44	PS00028
Domain	Znf_C2H2-like	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	1.26e-39	796	79	44	IPR015880
Domain	Znf_C2H2	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	2.05e-39	805	79	44	IPR007087
Domain	KRAB	ZNF132 ZNF514 ZNF17 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZNF154 ZNF157 ZNF530 ZNF658 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	2.22e-39	358	79	35	PS50805
Domain	KRAB	ZNF132 ZNF514 ZNF17 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZNF154 ZNF157 ZNF530 ZNF658 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	2.22e-39	358	79	35	PF01352
Domain	ZnF_C2H2	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 OVOL3 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	2.42e-39	808	79	44	SM00355
Domain	zf-C2H2_6	ZNF502 ZNF514 ZNF17 ZNF311 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZNF154 ZNF157 ZSCAN31 ZNF530 ZNF658 ZNF607 ZNF570 ZNF212 ZNF256 ZNF805 ZKSCAN8 ZNF814 ZNF79 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551	1.48e-31	314	79	29	PF13912
Domain	SCAN	ZNF263 ZSCAN20 ZSCAN31 ZNF165 ZSCAN26 ZKSCAN8	1.30e-07	56	79	6	SM00431
Domain	SCAN_BOX	ZNF263 ZSCAN20 ZSCAN31 ZNF165 ZSCAN26 ZKSCAN8	1.60e-07	58	79	6	PS50804
Domain	SCAN	ZNF263 ZSCAN20 ZSCAN31 ZNF165 ZSCAN26 ZKSCAN8	1.60e-07	58	79	6	PF02023
Domain	SCAN_dom	ZNF263 ZSCAN20 ZSCAN31 ZNF165 ZSCAN26 ZKSCAN8	1.60e-07	58	79	6	IPR003309
Domain	Retrov_capsid_C	ZNF263 ZSCAN20 ZSCAN31 ZNF165 ZSCAN26 ZKSCAN8	1.78e-07	59	79	6	IPR008916
Domain	Growth_fac_rcpt_	PCSK5 EYS FBN1 FBN2 PCSK6 JAG1 CCN3	4.34e-06	156	79	7	IPR009030
Domain	EGF-like_dom	PCSK5 EYS FBN1 FBN2 ADAM18 PCSK6 JAG1 ADAM8	1.03e-05	249	79	8	IPR000742
Domain	FBN	FBN1 FBN2	5.29e-05	3	79	2	IPR011398
Domain	EGF	PCSK5 EYS FBN1 FBN2 PCSK6 JAG1 ADAM8	6.13e-05	235	79	7	SM00181
Domain	PLAC	PCSK5 PCSK6 ADAMTS14	6.72e-05	19	79	3	IPR010909
Domain	PLAC	PCSK5 PCSK6 ADAMTS14	6.72e-05	19	79	3	PS50900
Domain	ADAM_Cys-rich	ADAM18 ADAMTS14 ADAM8	1.98e-04	27	79	3	IPR006586
Domain	ACR	ADAM18 ADAMTS14 ADAM8	1.98e-04	27	79	3	SM00608
Domain	hEGF	EYS FBN2 JAG1	2.21e-04	28	79	3	PF12661
Domain	GF_recep_IV	PCSK5 PCSK6	2.62e-04	6	79	2	PF14843
Domain	GF_recep_IV	PCSK5 PCSK6	2.62e-04	6	79	2	IPR032778
Domain	Peptidase_S8_Asp-AS	PCSK5 PCSK6	2.62e-04	6	79	2	IPR023827
Domain	PrprotnconvertsP	PCSK5 PCSK6	3.66e-04	7	79	2	IPR002884
Domain	P_proprotein	PCSK5 PCSK6	3.66e-04	7	79	2	PF01483
Domain	S8_pro-domain	PCSK5 PCSK6	3.66e-04	7	79	2	IPR032815
Domain	-	PCSK5 PCSK6	3.66e-04	7	79	2	3.30.70.850
Domain	S8_pro-domain	PCSK5 PCSK6	3.66e-04	7	79	2	PF16470
Domain	TB	FBN1 FBN2	3.66e-04	7	79	2	PF00683
Domain	EGF_3	EYS FBN1 FBN2 ADAM18 JAG1 ADAM8	4.81e-04	235	79	6	PS50026
Domain	Somatomedin_B	TINAG ENDOU	4.87e-04	8	79	2	PF01033
Domain	-	FBN1 FBN2	4.87e-04	8	79	2	3.90.290.10
Domain	Peptidase_M12B_N	ADAM18 ADAMTS14 ADAM8	5.96e-04	39	79	3	IPR002870
Domain	Pep_M12B_propep	ADAM18 ADAMTS14 ADAM8	5.96e-04	39	79	3	PF01562
Domain	Peptidase_S8_His-AS	PCSK5 PCSK6	6.24e-04	9	79	2	IPR022398
Domain	SO	TINAG ENDOU	6.24e-04	9	79	2	SM00201
Domain	TB	FBN1 FBN2	6.24e-04	9	79	2	PS51364
Domain	TB_dom	FBN1 FBN2	6.24e-04	9	79	2	IPR017878
Domain	Peptidase_S8_Ser-AS	PCSK5 PCSK6	6.24e-04	9	79	2	IPR023828
Domain	DISINTEGRIN_1	ADAM18 ADAMTS14 ADAM8	6.43e-04	40	79	3	PS00427
Domain	ADAM_MEPRO	ADAM18 ADAMTS14 ADAM8	6.43e-04	40	79	3	PS50215
Domain	DISINTEGRIN_2	ADAM18 ADAMTS14 ADAM8	6.43e-04	40	79	3	PS50214
Domain	Reprolysin	ADAM18 ADAMTS14 ADAM8	6.43e-04	40	79	3	PF01421
Domain	Peptidase_M12B	ADAM18 ADAMTS14 ADAM8	6.43e-04	40	79	3	IPR001590
Domain	Disintegrin_dom	ADAM18 ADAMTS14 ADAM8	6.92e-04	41	79	3	IPR001762
Domain	EGF_1	EYS FBN1 FBN2 ADAM18 JAG1 ADAM8	7.38e-04	255	79	6	PS00022
Domain	EGF_Ca-bd_CS	EYS FBN1 FBN2 JAG1	7.62e-04	97	79	4	IPR018097
Domain	Somatomedin_B_dom	TINAG ENDOU	7.78e-04	10	79	2	IPR001212
Domain	Peptidase_S8_subtilisin-rel	PCSK5 PCSK6	7.78e-04	10	79	2	IPR015500
Domain	SMB_1	TINAG ENDOU	7.78e-04	10	79	2	PS00524
Domain	SMB_2	TINAG ENDOU	7.78e-04	10	79	2	PS50958
Domain	SUBTILASE_ASP	PCSK5 PCSK6	7.78e-04	10	79	2	PS00136
Domain	SUBTILASE_HIS	PCSK5 PCSK6	7.78e-04	10	79	2	PS00137
Domain	SUBTILASE_SER	PCSK5 PCSK6	7.78e-04	10	79	2	PS00138
Domain	EGF_CA	EYS FBN1 FBN2 JAG1	8.23e-04	99	79	4	PS01187
Domain	EGF-like_CS	EYS FBN1 FBN2 ADAM18 JAG1 ADAM8	8.33e-04	261	79	6	IPR013032
Domain	ASX_HYDROXYL	EYS FBN1 FBN2 JAG1	8.55e-04	100	79	4	PS00010
Domain	EGF_2	EYS FBN1 FBN2 ADAM18 JAG1 ADAM8	9.02e-04	265	79	6	PS01186
Domain	Peptidase_S8	PCSK5 PCSK6	9.48e-04	11	79	2	PF00082
Domain	-	PCSK5 PCSK6	9.48e-04	11	79	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	PCSK5 PCSK6	9.48e-04	11	79	2	IPR000209
Domain	EGF-type_Asp/Asn_hydroxyl_site	EYS FBN1 FBN2 JAG1	1.06e-03	106	79	4	IPR000152
Domain	PLAC	PCSK5 PCSK6	1.56e-03	14	79	2	PF08686
Domain	EGF_CA	EYS FBN1 FBN2 JAG1	1.78e-03	122	79	4	SM00179
Domain	EGF-like_Ca-bd_dom	EYS FBN1 FBN2 JAG1	1.89e-03	124	79	4	IPR001881
Domain	Disintegrin_CS	ADAM18 ADAM8	2.04e-03	16	79	2	IPR018358
Domain	EGF_extracell	ADAM18 JAG1 ADAM8	2.10e-03	60	79	3	IPR013111
Domain	EGF_2	ADAM18 JAG1 ADAM8	2.10e-03	60	79	3	PF07974
Domain	Propept_inh	PCSK5 PCSK6	2.31e-03	17	79	2	IPR009020
Domain	Furin_repeat	PCSK5 PCSK6	2.59e-03	18	79	2	IPR006212
Domain	ADAM_CR	ADAM18 ADAM8	2.59e-03	18	79	2	PF08516
Domain	FU	PCSK5 PCSK6	2.59e-03	18	79	2	SM00261
Domain	-	ADAM18 ADAM8	3.19e-03	20	79	2	4.10.70.10
Domain	DISIN	ADAM18 ADAM8	3.52e-03	21	79	2	SM00050
Domain	Disintegrin	ADAM18 ADAM8	3.52e-03	21	79	2	PF00200
Domain	MetalloPept_cat_dom	ADAM18 ADAMTS14 ADAM8	4.90e-03	81	79	3	IPR024079
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF514 ZNF17 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZNF154 ZNF157 ZNF530 ZNF658 ZNF607 ZNF559 ZNF570 ZNF212 JAG1 ZNF256 ZFP1 CHEK2 ZKSCAN8 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	7.87e-21	1387	59	35	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF263 ZNF773 ZNF605 ZNF212 ZFP1 CHEK2 ZKSCAN8 ZNF814 ZNF418 ZNF416 ZNF551 ZNF2	6.58e-05	768	59	12	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF263 ZNF773 ZNF605 ZNF212 ZFP1 CHEK2 ZKSCAN8 BAZ1B ZNF814 ZNF418 ZNF416 ZNF551 ZNF2	2.49e-04	1022	59	13	MM15436
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF17 ZNF311 ZNF776 ZNF211 ZNF607 ZFP1 ZNF805 ZKSCAN8 ZNF552	4.33e-10	181	81	9	37372979
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF17 ZSCAN20 ZFP1 ZNF551	8.19e-07	31	81	4	2288909
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN1 FBN2 JAG1	1.01e-06	9	81	3	12122015
Pubmed	The zinc finger-associated SCAN box is a conserved oligomerization domain.	ZNF165 ZKSCAN8 ZNF79	1.01e-06	9	81	3	10567577
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF462 ZNF773 ZFP1 ZNF552 ZNF625	1.52e-06	83	81	5	20562864
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	5.36e-06	2	81	2	12399449
Pubmed	Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease.	PCSK5 PCSK6	5.36e-06	2	81	2	8335106
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	5.36e-06	2	81	2	21851253
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	5.36e-06	2	81	2	12429739
Pubmed	A high-throughput screening identifies ZNF418 as a novel regulator of the ubiquitin-proteasome system and autophagy-lysosomal pathway.	ZNF418 ZNF416	5.36e-06	2	81	2	33249983
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	5.36e-06	2	81	2	24833718
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	5.36e-06	2	81	2	30044367
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	5.36e-06	2	81	2	21440062
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	5.36e-06	2	81	2	15131124
Pubmed	Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4.	PCSK5 PCSK6	5.36e-06	2	81	2	8468318
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	5.36e-06	2	81	2	24265020
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	5.36e-06	2	81	2	12524050
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	5.36e-06	2	81	2	20529844
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	5.36e-06	2	81	2	25524144
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	5.36e-06	2	81	2	20404337
Pubmed	Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases.	PCSK5 PCSK6	5.36e-06	2	81	2	18061232
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	5.36e-06	2	81	2	23133647
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	5.36e-06	2	81	2	8791520
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	5.36e-06	2	81	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	5.36e-06	2	81	2	35419902
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	5.36e-06	2	81	2	8307578
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	5.36e-06	2	81	2	16407178
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	5.36e-06	2	81	2	10504303
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	5.36e-06	2	81	2	1852206
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	5.36e-06	2	81	2	10359653
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	5.36e-06	2	81	2	7744963
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	5.36e-06	2	81	2	26408953
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	5.36e-06	2	81	2	18006876
Pubmed	Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.	ZNF132 ZNF134 ZNF154	8.08e-06	17	81	3	7557990
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF462 ZNF776 SETX ZNF570 ZSCAN26 ZFP1 ZKSCAN8 BAZ1B PHF14	1.23e-05	608	81	9	36089195
Pubmed	Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain.	ZNF211 ZNF212	1.60e-05	3	81	2	7633419
Pubmed	Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.	FBN1 FBN2	1.60e-05	3	81	2	10825173
Pubmed	Maturation of HIV envelope glycoprotein precursors by cellular endoproteases.	PCSK5 PCSK6	1.60e-05	3	81	2	11063880
Pubmed	A strategy for cloning the hereditary hemochromatosis gene.	ZNF165 ZKSCAN8	1.60e-05	3	81	2	8673473
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	FBN1 FBN2	1.60e-05	3	81	2	30201140
Pubmed	Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.	FBN1 FBN2	1.60e-05	3	81	2	20855508
Pubmed	Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.	PCSK5 PCSK6	1.60e-05	3	81	2	8670066
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF462 ZNF263 ZNF773 ZSCAN20 ZFP36L2 ZNF212 ZKSCAN8 BAZ1B PHF14 ZNF2	1.84e-05	808	81	10	20412781
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	FBN1 ZNF211 FBN2 ZNF730	2.36e-05	71	81	4	33541421
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	FBN1 FBN2 JAG1	3.04e-05	26	81	3	34189436
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 FBN2	3.20e-05	4	81	2	12429738
Pubmed	Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain.	ZNF165 ZKSCAN8	3.20e-05	4	81	2	9244436
Pubmed	CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfaces.	PCSK5 PCSK6	3.20e-05	4	81	2	16829522
Pubmed	Human eye development is characterized by coordinated expression of fibrillin isoforms.	FBN1 FBN2	3.20e-05	4	81	2	25406291
Pubmed	Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.	PCSK5 PCSK6	3.20e-05	4	81	2	8615794
Pubmed	Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.	FBN1 FBN2	3.20e-05	4	81	2	20729550
Pubmed	The proprotein convertases furin and PACE4 play a significant role in tumor progression.	PCSK5 PCSK6	3.20e-05	4	81	2	10900462
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN2	3.20e-05	4	81	2	25034023
Pubmed	Neurotrophin secretion: current facts and future prospects.	PCSK5 PCSK6	3.20e-05	4	81	2	12787574
Pubmed	Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis.	ZNF418 ZNF416	3.20e-05	4	81	2	29065170
Pubmed	Fast Ca2+ Transients of Inner Hair Cells Arise Coupled and Uncoupled to Ca2+ Waves of Inner Supporting Cells in the Developing Mouse Cochlea.	CACNA1D P2RX3	3.20e-05	4	81	2	30104958
Pubmed	Retroviral envelope glycoprotein processing: structural investigation of the cleavage site.	PCSK5 PCSK6	3.20e-05	4	81	2	9521771
Pubmed	Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.	FBN1 FBN2	3.20e-05	4	81	2	16835936
Pubmed	Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.	FBN1 CCN3	3.20e-05	4	81	2	20182440
Pubmed	Identification of a conserved family of Meis1-related homeobox genes.	MEIS3 MEIS3P1	3.20e-05	4	81	2	9049632
Pubmed	Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.	FBN1 FBN2	5.33e-05	5	81	2	26601954
Pubmed	Processing of prothyrotropin-releasing hormone by the family of prohormone convertases.	PCSK5 PCSK6	5.33e-05	5	81	2	9242664
Pubmed	Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins.	ZFP36L2 JAG1	5.33e-05	5	81	2	38157296
Pubmed	Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.	FBN1 FBN2	5.33e-05	5	81	2	17255108
Pubmed	Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates.	PCSK5 PCSK6	5.33e-05	5	81	2	11380615
Pubmed	POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.	FBN1 FBN2	5.33e-05	5	81	2	34411563
Pubmed	Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.	FBN1 FBN2	5.33e-05	5	81	2	12590922
Pubmed	Development, composition, and structural arrangements of the ciliary zonule of the mouse.	FBN1 FBN2	5.33e-05	5	81	2	23493297
Pubmed	Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.	PCSK5 PCSK6	5.33e-05	5	81	2	18664504
Pubmed	Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.	PCSK5 PCSK6	7.99e-05	6	81	2	9291583
Pubmed	The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.	PCSK5 PCSK6	7.99e-05	6	81	2	16135528
Pubmed	High-throughput mammalian two-hybrid screening for protein-protein interactions using transfected cell arrays.	FBN2 JAG1	7.99e-05	6	81	2	18254948
Pubmed	Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines.	PCSK5 PCSK6	7.99e-05	6	81	2	8940009
Pubmed	Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.	FBN1 FBN2	7.99e-05	6	81	2	7873879
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF502 ZNF462 ZNF263 ZNF773 FBN2 ERGIC3 ZNF658 ZSCAN26 ZKSCAN8 BAZ1B ZNF551	1.07e-04	1203	81	11	29180619
Pubmed	Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.	FBN1 JAG1	1.12e-04	7	81	2	29093270
Pubmed	Identification of SCAN dimerization domains in four gene families.	ZNF263 ZKSCAN8	1.12e-04	7	81	2	11342224
Pubmed	Proteolytic processing in the secretory pathway.	PCSK5 PCSK6	1.12e-04	7	81	2	10409610
Pubmed	Regulation of limb patterning by extracellular microfibrils.	FBN1 FBN2	1.12e-04	7	81	2	11470817
Pubmed	The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.	PCSK5 PCSK6	1.12e-04	7	81	2	7819324
Pubmed	Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.	FBN1 FBN2	1.49e-04	8	81	2	23055981
Pubmed	Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.	FBN1 FBN2	1.49e-04	8	81	2	31201465
Pubmed	Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.	PCSK5 PCSK6	1.49e-04	8	81	2	7782070
Pubmed	Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.	PCSK5 PCSK6	1.49e-04	8	81	2	9885250
Pubmed	Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals.	PCSK5 PCSK6	1.49e-04	8	81	2	10037747
Pubmed	Targeting of bone morphogenetic protein growth factor complexes to fibrillin.	FBN1 FBN2	1.49e-04	8	81	2	18339631
Pubmed	The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.	PCSK5 PCSK6	1.91e-04	9	81	2	23775089
Pubmed	The activation and physiological functions of the proprotein convertases.	PCSK5 PCSK6	1.91e-04	9	81	2	18343183
Pubmed	SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.	PCSK5 PCSK6	1.91e-04	9	81	2	8698813
Pubmed	Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.	FBN1 FBN2	1.91e-04	9	81	2	38844137
Pubmed	The prohormone theory and the proprotein convertases: it is all about serendipity.	PCSK5 PCSK6	1.91e-04	9	81	2	21805236
Pubmed	The proprotein convertases, 20 years later.	PCSK5 PCSK6	1.91e-04	9	81	2	21805237
Pubmed	The biology and therapeutic targeting of the proprotein convertases.	PCSK5 PCSK6	1.91e-04	9	81	2	22679642
Pubmed	Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.	FBN1 FBN2	2.38e-04	10	81	2	30738849
Pubmed	Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.	PCSK5 PCSK6	2.38e-04	10	81	2	16163737
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF462 LMCD1 PCSK6 ZKSCAN8 BAZ1B PHF14 MEIS3 FHL3	2.49e-04	709	81	8	22988430
Pubmed	Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.	FBN1 FBN2	3.48e-04	12	81	2	26405179
Pubmed	A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development.	FBN1 FBN2	3.48e-04	12	81	2	36779913
Pubmed	A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.	CHEK2 FHL3	5.52e-04	15	81	2	28094252
Pubmed	Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.	PCSK5 PCSK6	6.29e-04	16	81	2	20876279
Interaction	TRIM28 interactions	ZNF462 ZNF514 ZNF17 ZNF311 ZNF263 ZNF776 ZNF773 ZNF211 ZNF658 ZNF607 ZNF256 ZFP1 CHEK2 ZNF805 ZKSCAN8 BAZ1B ZNF552 FHL3 ZNF418 ZNF416 ZNF2 ZNF304	2.32e-08	1474	78	22	int:TRIM28
Interaction	CENPB interactions	ZNF514 ZNF17 ZNF311 ZNF263 ZKSCAN8 MAP10 ZNF418 ZNF416	2.68e-08	124	78	8	int:CENPB
Interaction	TRIM41 interactions	ZNF134 ZNF263 ZNF773 ZNF165 ZSCAN26 ZFP1 ZNF552 ZNF2	2.39e-06	223	78	8	int:TRIM41
Interaction	TRIM39 interactions	ZNF17 ZNF311 ZNF776 ZNF773 ZNF658 ZNF416	3.87e-06	108	78	6	int:TRIM39
Interaction	MFAP2 interactions	FBN1 FBN2 JAG1	1.20e-05	12	78	3	int:MFAP2
Interaction	ZNF837 interactions	PCSK5 ZNF17 SPRED2 ZNF165 ZNF552	1.37e-05	79	78	5	int:ZNF837
Interaction	CBX5 interactions	ZNF462 ZNF17 ZNF263 ZNF776 ZNF773 ZFP1 ZNF552 ZNF625	7.00e-05	356	78	8	int:CBX5
Interaction	YJU2B interactions	ZNF17 ZNF165 ZKSCAN8 ZNF79	1.04e-04	63	78	4	int:YJU2B
Interaction	ZDHHC15 interactions	FBN1 ZNF211 FBN2 ERGIC3 ZNF730	1.25e-04	125	78	5	int:ZDHHC15
Interaction	CARD10 interactions	ZNF613 ZNF165 ZNF559 ZFP1 ZNF552	1.34e-04	127	78	5	int:CARD10
Interaction	KRTAP10-7 interactions	PCSK5 ZNF165 ZNF256 ZSCAN26 ZNF625 ZNF418 ZNF2	1.40e-04	293	78	7	int:KRTAP10-7
Interaction	ZKSCAN8 interactions	ZNF263 ZSCAN20 ZNF165 ZSCAN26 ZKSCAN8	1.50e-04	130	78	5	int:ZKSCAN8
Interaction	SCAND1 interactions	ZNF263 ZSCAN20 ZNF165 ZKSCAN8	1.57e-04	70	78	4	int:SCAND1
Cytoband	19q13.43	ZNF776 ZNF671 ZNF773 ZNF586 ZNF530 ZNF256 ZNF805 ZNF814 ZNF552 ZNF470 ZNF418 ZNF548 ZNF551	5.38e-22	87	81	13	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF132 ZNF17 ZNF134 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF613 ZNF154 ZNF530 OVOL3 ZNF607 ZNF570 ZNF256 ZNF805 ZNF814 ZNF552 ZNF470 MEIS3 ZNF418 ZNF416 ZNF548 ZNF551 ZNF304	2.35e-20	1192	81	25	chr19q13
Cytoband	19q13.4	ZNF132 ZNF17 ZNF134 ZNF211 ZNF154 ZNF416 ZNF304	1.07e-10	79	81	7	19q13.4
Cytoband	Ensembl 112 genes in cytogenetic band chr6p22	ZNF311 ZSCAN31 ZNF165 ZSCAN26 ZKSCAN8	5.65e-04	378	81	5	chr6p22
Cytoband	6p21.31	ZSCAN31 ZSCAN26	2.41e-03	41	81	2	6p21.31
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF502 ZNF462 ZNF132 ZNF514 ZNF17 ZNF134 ZNF311 ZNF263 ZNF776 ZNF671 ZNF773 ZNF586 ZNF211 ZNF605 ZNF613 ZSCAN20 ZNF154 ZNF157 ZSCAN31 ZNF530 ZNF658 ZNF165 ZNF607 ZNF559 ZNF570 ZNF212 ZNF256 ZSCAN26 ZFP1 ZNF805 ZKSCAN8 ZNF814 ZNF552 ZNF79 ZNF470 ZNF625 ZNF418 ZNF416 ZNF548 ZNF730 ZNF551 ZNF2 ZNF304	4.40e-43	718	69	43	28
GeneFamily	Proprotein convertase subtilisin/kexin family	PCSK5 PCSK6	5.08e-04	9	69	2	973
GeneFamily	TALE class homeoboxes and pseudogenes	MEIS3 MEIS3P1	4.40e-03	26	69	2	526
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM18 ADAM8	4.74e-03	27	69	2	47
Coexpression	VERHAAK_GLIOBLASTOMA_CLASSICAL	PCSK5 ZNF134 ZNF671 ZNF211 JAG1 ZNF304	1.01e-05	161	80	6	M2121
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D FBN1 ZNF613 JAG1 ZNF470 ZNF418	1.16e-06	186	81	6	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D FBN1 ZNF613 JAG1 ZNF470 ZNF418	1.16e-06	186	81	6	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PCSK5 ZNF776 ZNF530 ZNF559 ZNF551	3.30e-06	125	81	5	43aa4b77dccf0ea2979218826af16034f2017c3a
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PCSK5 ZNF776 ZNF530 ZNF559 ZNF551	1.24e-05	164	81	5	d6806deabf5f5c355934387be2baae125ac33fb8
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZNF462 ZNF17 ZNF530 TDRD1 ZNF2	1.31e-05	166	81	5	8d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell	Nasal_Brush-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ZNF263 ZNF773 ZNF613 ZNF256 ZNF548	1.56e-05	172	81	5	58eaadf12366701103a0d1f133462c9495fedc30
ToppCell	Nasal_Brush-Epithelial-Basal_1\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	ZNF263 ZNF773 ZNF613 ZNF256 ZNF548	1.56e-05	172	81	5	4483073469001770015526303772fd54906c5d68
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 CACNA1D FBN2 ENDOU ADAMTS14	1.89e-05	179	81	5	55bc69f107fc710db7617c428575792adfdbbcc1
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PCSK5 CD82 EDAR LMCD1 FHL3	2.33e-05	187	81	5	387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CD82 EDAR LMCD1 JAG1 ADAMTS14	2.39e-05	188	81	5	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK5 CD82 EDAR LMCD1 JAG1	2.52e-05	190	81	5	71a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK5 CD82 LMCD1 ADAMTS14 FHL3	2.65e-05	192	81	5	7ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell	NS-critical-d_0-4-Epithelial-Basal\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ZNF502 ZNF514 ZNF134 ZFP1 MAP10	2.71e-05	193	81	5	1affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-1\|TCGA-Brain / Sample_Type by Project: Shred V9	ZNF776 ZNF530 JAG1 ZNF416	2.85e-05	96	81	4	14cad3fae85e41b9f629b8a81a433b652276930c
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	PCSK5 CD82 EDAR LMCD1 FHL3	2.92e-05	196	81	5	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF263 ZNF671 ZNF607 ZNF805 ZNF79	2.92e-05	196	81	5	7e98380d815fbf6254289ace2af37aac6fef51e8
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	OVOL3 ZNF570 ZNF814 ZNF730 ZNF551	2.99e-05	197	81	5	fd76cc5e12c7e7943a48f739e4f0626ff7211f51
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	SETX FBN2 ZSCAN31 LMCD1 JAG1	3.14e-05	199	81	5	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2	1.76e-05	3	72	2	DOID:65 (implicated_via_orthology)
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	3.51e-05	4	72	2	DOID:0060249 (is_implicated_in)
Disease	restless legs syndrome (implicated_via_orthology)	MEIS3 MEIS3P1	1.63e-04	8	72	2	DOID:0050425 (implicated_via_orthology)
Disease	anxiety, stress-related disorder, major depressive disorder	ZSCAN31 ZSCAN26 ZKSCAN8	1.96e-04	46	72	3	EFO_0005230, EFO_0010098, MONDO_0002009
Disease	Familial thoracic aortic aneurysm and aortic dissection	FBN1 FBN2 JAG1	2.99e-04	53	72	3	C4707243
Disease	Colorectal Neoplasms	FBN2 ZFP36L2 CHEK2 LY96 FHL3	5.89e-04	277	72	5	C0009404
Disease	leukemia (implicated_via_orthology)	MEIS3 MEIS3P1	9.77e-04	19	72	2	DOID:1240 (implicated_via_orthology)
Disease	Deaf Mutism	CACNA1D JAG1	1.08e-03	20	72	2	C4082305
Disease	Deafness, Acquired	CACNA1D JAG1	1.08e-03	20	72	2	C0751068
Disease	Hearing Loss, Extreme	CACNA1D JAG1	1.08e-03	20	72	2	C0086395
Disease	Complete Hearing Loss	CACNA1D JAG1	1.08e-03	20	72	2	C0581883
Disease	Prelingual Deafness	CACNA1D JAG1	1.08e-03	20	72	2	C0011052
Disease	Bilateral Deafness	CACNA1D JAG1	1.08e-03	20	72	2	C3665473
Disease	nose morphology measurement, mouth morphology measurement	MEIS3 MEIS3P1	1.20e-03	21	72	2	EFO_0007843, EFO_0007955
Disease	Deafness	CACNA1D JAG1	1.70e-03	25	72	2	C0011053

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRIGDACCAKYTSDD	TDRD1	991	Q9BXT4
CKDHTVSGDEDYCPR	BAZ1B	941	Q9UIG0
RKSIDPECDFTEYCN	ADAM18	451	Q9Y3Q7
AEESCFSYDILPGCK	ADAM8	526	P78325
GRDKSCEYCFDEPLL	CHEK2	116	O96017
CNSEECPGTYEDFRA	ADAMTS14	601	Q8WXS8
TYPCSCEVKGEEDNS	CD82	171	P27701
SDDLSSPCYSEDFCT	MAP10	701	Q9P2G4
GAYCEKSIDNCAEPE	EYS	1111	Q5T1H1
DEDYGCVPCPAEKFS	EDAR	66	Q9UNE0
RCYSKCPEGSYAEDG	PCSK5	1261	Q92824
DCEPGTYFDSELIRC	PCSK6	831	P29122
APTSCQGRCYEAFDK	ENDOU	86	P21128
SLDPDRCESCYGAEA	ERGIC3	136	Q9Y282
EQIRKSPDCTFYCAD	KCNJ15	331	Q99712
GCREDFEDYPASCPS	MEIS3	181	Q99687
YGAKECSFCEDPRFA	PHF14	436	O94880
PRCSGCDEIIFAEDY	LMCD1	306	Q9NZU5
CEDCGFTSSRPDTYA	OVOL3	191	O00110
TSRDEDPYCVACFGE	FHL3	201	Q13643
SDLEPCDESSGLYCD	CCN3	76	P48745
CDESSGLYCDRSADP	CCN3	81	P48745
SDGRYCKDINECETP	FBN1	606	P35555
KEVICRGSDDDYSFC	LY96	91	Q9Y6Y9
SFKCLCNEGYELTPD	FBN2	1996	P35556
FYRCTDEAKSNPEEC	CACNA1D	1041	Q01668
FCPESEEKYRCVSDS	P2RX3	106	P56373
PGDRKCTRDECDTYF	JAG1	61	P78504
CREDFEDYPASCPSL	MEIS3P1	81	A6NDR6
PSGEFQTADEDLCYC	SETX	26	Q7Z333
DSCSDCSYRDKPGSS	SHCBP1	41	Q8NEM2
TGERPYECNECAKTF	ZFP1	291	Q6P2D0
PYECDECGKAFSNRS	ZNF132	346	P52740
ERPYECSECGRSFAE	ZNF586	231	Q9NXT0
RERPYECSECGKSFS	ZNF586	286	Q9NXT0
GERPYECSDCGKSFA	ZNF586	341	Q9NXT0
DSAKVPSDEYCPACR	USPL1	36	Q5W0Q7
TGERPYECSECGKFF	ZNF671	336	Q8TAW3
GERPYECSECGKAFS	ZNF671	421	Q8TAW3
GERPYECGECAKTFS	ZNF157	186	P51786
TGERPYECTECGKTF	ZNF157	241	P51786
ESPYECSVCSKAFFD	ZNF2	226	Q9BSG1
PYECEECGKAFSRRS	ZSCAN31	266	Q96LW9
GEKLYECSECGRSFS	ZSCAN20	871	P17040
GSECPVCYEKFRDLE	RNF222	11	A6NCQ9
GEKPYECSECGRAFS	ZNF514	256	Q96K75
GERPYECSECGKSFS	ZNF256	571	Q9Y2P7
PYECKECGEAFRTSR	ZNF607	196	Q96SK3
GDRPYECSECEKSFS	ZNF551	471	Q7Z340
TGTRPYECSECGKSF	ZNF551	526	Q7Z340
ERPYECSECGKSFSQ	ZNF551	556	Q7Z340
ECIECGKAFSDGSYL	ZNF470	566	Q6ECI4
EERPYECNECGKFFT	ZNF211	281	Q13398
ERPYECSECGKSFSQ	ZNF211	366	Q13398
ERPYECSECGKSFSQ	ZNF211	506	Q13398
YTDPCSCDTSDEKFC	SPRED2	361	Q7Z698
STEGESESRPGKYCC	RGS14	291	O43566
PYECEECGKAFNRSS	ZNF730	451	Q6ZMV8
TGRKPYECSDCEKTF	ZNF658	681	Q5TYW1
ERPYECSECGKFFSQ	ZNF773	356	Q6PK81
EEKPYQCSECGEAFR	ZSCAN26	446	Q16670
GERPYECSECGKSFS	ZNF416	266	Q9BWM5
ERPYECSDCGKSFTH	ZNF552	321	Q9H707
PYECSECGKSFAESS	ZNF552	351	Q9H707
PYECIECGKAFSNDS	ZNF570	441	Q96NI8
ERPYECGECGKSFSQ	ZNF418	311	Q8TF45
SERPYECEECGKCFS	ZNF418	366	Q8TF45
RPYTCEECGKAFSRS	ZNF502	181	Q8TBZ5
GEKPYICSECGSSFR	ZNF502	291	Q8TBZ5
EKPYTCSDCGKAFRD	ZNF613	481	Q6PF04
TGEKPYECSECGRAF	ZNF165	451	P49910
TGERPYECSECGKFF	ZNF548	416	Q8NEK5
GERPYSCTECEKSFV	ZNF212	451	Q9UDV6
CDGCDFRAPSYEDLK	ZNF462	6	Q96JM2
GERPYECSECGKVFS	ZNF530	431	Q6P9A1
GERPYECSECGKSFS	ZNF530	571	Q6P9A1
TGERPYECSECGKFF	ZNF304	386	Q9HCX3
SYPCSFKDCAERELV	ZFAND1	61	Q8TCF1
GERPYECSECGKSFS	ZNF154	241	Q13106
GSRPYECSECGKSFT	ZNF154	381	Q13106
PYDCEECGKSFISRS	ZNF625	96	Q96I27
NSDCCPDYKSFCREE	TINAG	91	Q9UJW2
TELCRPFEESGTCKY	ZFP36L2	156	P47974
PFECEECGKAFRYSS	ZNF559	436	Q9BR84
PYRCSECEKAFSDCS	ZNF79	276	Q15937
PYECSECRKTFSEKS	ZNF605	476	Q86T29
EKPYECSECGKAFSR	ZNF805	536	Q5CZA5
EKPYECSECGKAFSR	ZNF134	201	P52741
PYECSECGKTFSRKD	ZNF134	231	P52741
GERPYECSECGKAYS	ZNF134	396	P52741
TGERPYECSECGKFF	ZNF17	521	P17021
PYECSECGKSFAESS	ZNF814	771	B7Z6K7
PYECDECGKTFRRSS	ZKSCAN8	461	Q15776
PYECEECGKAFSGSS	ZNF311	386	Q5JNZ3
TGRKPYECSDCEKTF	ZNF658B	441	Q4V348
ERPYKCSECGESFSR	ZNF263	656	O14978
GERPYECDECGKSFS	ZNF776	316	Q68DI1