Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpolypeptide N-acetylgalactosaminyltransferase activity

GALNT14 GALNT3 GALNT16

1.47e-04201043GO:0004653
GeneOntologyMolecularFunctionATP-dependent activity

DNAH10 MYO5A MYO7B DHX37 ATP13A5 ABCC6 MYO5C DNAH1 BPTF DHX29 AFG1L

3.56e-0461410411GO:0140657
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH10 MYO5A MYO7B MYO5C DNAH1

3.82e-041181045GO:0003774
GeneOntologyBiologicalProcessactin filament-based transport

MYO5A MYO5C SYNE2

2.11e-05111063GO:0099515
DomainDUF1712

CCZ1B CCZ1

3.07e-0521042PF08217
DomainDUF1712_fun

CCZ1B CCZ1

3.07e-0521042IPR013176
DomainAngiomotin

AMOT AMOTL1

9.18e-0531042IPR009114
DomainZnf_CHHC

HNRNPH1 HNRNPH2

9.18e-0531042IPR012996
DomainAngiomotin_C

AMOT AMOTL1

9.18e-0531042IPR024646
Domainzf-RNPHF

HNRNPH1 HNRNPH2

9.18e-0531042PF08080
DomainAngiomotin_C

AMOT AMOTL1

9.18e-0531042PF12240
DomainSPRY

RANBP9 TRIM64 TRIM27 TRIM64B TRIM36

1.80e-04941045PF00622
DomainSPRY_dom

RANBP9 TRIM64 TRIM27 TRIM64B TRIM36

1.80e-04941045IPR003877
DomainSpectrin_bsu

SPTB SPTBN4

1.83e-0441042IPR016343
DomainB30.2/SPRY

RANBP9 TRIM64 TRIM27 TRIM64B TRIM36

1.89e-04951045IPR001870
DomainB302_SPRY

RANBP9 TRIM64 TRIM27 TRIM64B TRIM36

1.89e-04951045PS50188
DomainConA-like_dom

RANBP9 TRIM64 TRIM27 TRIM64B FAT2 COL14A1 TRIM36

2.25e-042191047IPR013320
DomainSpectrin

SPTB SPTBN4 SYNE2

2.74e-04231043PF00435
DomainACTININ_2

SPTB SPTBN4 SYNE2

2.74e-04231043PS00020
DomainACTININ_1

SPTB SPTBN4 SYNE2

2.74e-04231043PS00019
DomainActinin_actin-bd_CS

SPTB SPTBN4 SYNE2

2.74e-04231043IPR001589
DomainMyosin_S1_N

MYO5A MYO5C

3.04e-0451042IPR008989
DomainRicin_B_lectin

GALNT14 GALNT3 GALNT16

3.53e-04251043PF00652
DomainZnf_C3HC4_RING-type

TRIM64 TRIM27 TTC3 TRIM64B RNF103 TRIM36

4.03e-041721046IPR018957
DomainDilute_dom

MYO5A MYO5C

4.54e-0461042IPR002710
DomainDIL

MYO5A MYO5C

4.54e-0461042PF01843
DomainDILUTE

MYO5A MYO5C

4.54e-0461042PS51126
DomainDIL

MYO5A MYO5C

4.54e-0461042SM01132
DomainCH

SPTB SPECC1 SPTBN4 SYNE2

4.73e-04651044SM00033
DomainRICIN

GALNT14 GALNT3 GALNT16

4.97e-04281043SM00458
DomainRICIN_B_LECTIN

GALNT14 GALNT3 GALNT16

4.97e-04281043PS50231
DomainSpectrin_repeat

SPTB SPTBN4 SYNE2

5.52e-04291043IPR002017
DomainBBOX

TRIM64 TRIM27 TRIM64B TRIM36

5.94e-04691044SM00336
DomainRicin_B_lectin

GALNT14 GALNT3 GALNT16

6.10e-04301043IPR000772
DomainGlycos_transf_2

GALNT14 GALNT3 GALNT16

6.10e-04301043PF00535
DomainGlyco_trans_2-like

GALNT14 GALNT3 GALNT16

6.10e-04301043IPR001173
DomainButyrophylin

TRIM64 TRIM27 TRIM64B TRIM36

6.27e-04701044IPR003879
DomainCH

SPTB SPECC1 SPTBN4 SYNE2

6.27e-04701044PF00307
Domain-

SPTB SPECC1 SPTBN4 SYNE2

6.62e-047110441.10.418.10
Domain-

TRIM64 TRIM27 TRIM64B TRIM36

6.62e-047110444.10.45.10
Domainzf-B_box

TRIM64 TRIM27 TRIM64B TRIM36

6.98e-04721044PF00643
DomainCH

SPTB SPECC1 SPTBN4 SYNE2

7.35e-04731044PS50021
DomainSPEC

SPTB SPTBN4 SYNE2

7.40e-04321043SM00150
DomainSpectrin/alpha-actinin

SPTB SPTBN4 SYNE2

7.40e-04321043IPR018159
DomainCH-domain

SPTB SPECC1 SPTBN4 SYNE2

8.14e-04751044IPR001715
DomainZF_BBOX

TRIM64 TRIM27 TRIM64B TRIM36

1.04e-03801044PS50119
DomainZnf_B-box

TRIM64 TRIM27 TRIM64B TRIM36

1.09e-03811044IPR000315
DomainMyosin_head_motor_dom

MYO5A MYO7B MYO5C

1.23e-03381043IPR001609
DomainMYOSIN_MOTOR

MYO5A MYO7B MYO5C

1.23e-03381043PS51456
DomainMyosin_head

MYO5A MYO7B MYO5C

1.23e-03381043PF00063
DomainMYSc

MYO5A MYO7B MYO5C

1.23e-03381043SM00242
DomainSPRY

RANBP9 TRIM64 TRIM27 TRIM64B

1.42e-03871044SM00449
Domainzf-C3HC4

TRIM64 TRIM27 TTC3 TRIM64B RNF103 TRIM36

1.55e-032231046PF00097
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH1

2.68e-03141042IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH1

2.68e-03141042IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH1

2.68e-03141042IPR013602
DomainDHC_N2

DNAH10 DNAH1

2.68e-03141042PF08393
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH1

2.68e-03141042IPR011704
DomainMT

DNAH10 DNAH1

2.68e-03141042PF12777
DomainAAA_8

DNAH10 DNAH1

2.68e-03141042PF12780
DomainAAA_5

DNAH10 DNAH1

2.68e-03141042PF07728
DomainDHC_fam

DNAH10 DNAH1

3.08e-03151042IPR026983
DomainDynein_heavy

DNAH10 DNAH1

3.08e-03151042PF03028
DomainDynein_heavy_dom

DNAH10 DNAH1

3.08e-03151042IPR004273
DomainNicotinic_acetylcholine_rcpt

CHRNA6 CHRNB1

3.50e-03161042IPR002394
Domain-

FGD2 TRIM64 TRIM27 TTC3 TRIM64B BPTF RNF103 TRIM36

3.61e-0344910483.30.40.10
DomainDUF1605

DHX37 DHX29

3.95e-03171042IPR011709
DomainOB_NTP_bind

DHX37 DHX29

3.95e-03171042PF07717
DomainZnf_RING/FYVE/PHD

FGD2 TRIM64 TRIM27 TTC3 TRIM64B BPTF RNF103 TRIM36

4.12e-034591048IPR013083
DomainHA2

DHX37 DHX29

4.43e-03181042SM00847
DomainHA2

DHX37 DHX29

4.43e-03181042PF04408
DomainHelicase-assoc_dom

DHX37 DHX29

4.43e-03181042IPR007502
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ITCH MYO5A LEMD3 MRPS35 DNAJC21 TRIM27 TTC3 TFAM NDUFB10 DEGS1 ITPR2 NBAS NDUFAF4 CDK5RAP3 DNAJC14 SUPT6H PGRMC2 SYNE2 MAP7D2 COL14A1 DHX29

3.81e-0914871062133957083
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

GALNT3 MAP1B RANBP9 XPO4 MRPS35 TRIM27 SPECC1 TFAM NDUFB10 ITPR2 IWS1 NBAS NDUFAF4 PGRMC2 SYNE2 DHX29 SH3BGRL2

1.68e-0614401061730833792
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATG5 PPP4R1 ATRN ITCH CEP85 MYO5A SPTB RANBP9 MRPS35 ZNF214 ANKRD6 TTC3 SPECC1 SPTBN4 DNAJC14 RCBTB1

1.78e-0612851061635914814
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

GALNT3 MYO5A LEMD3 MRPS35 DNAJC21 TRIM27 SPECC1 TFAM IWS1 CDK5RAP3 ANAPC1 INTS13 SUPT6H ISG20L2 MED23 PLEKHA7 DHX29

2.83e-0614971061731527615
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

LEMD3 HNRNPH1 HNRNPH2 ITPR2 ANAPC1 SUPT6H AMOT MED23 DHX29

8.51e-06440106934244565
Pubmed

Human angiomotin-like 1 associates with an angiomotin protein complex through its coiled-coil domain and induces the remodeling of the actin cytoskeleton.

AMOT AMOTL1

9.20e-062106219565639
Pubmed

Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.

IWS1 SUPT6H

9.20e-062106230208029
Pubmed

Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin.

MYO5A MYO5C

9.20e-062106226912658
Pubmed

Human myosin-Vc is a novel class V myosin expressed in epithelial cells.

MYO5A MYO5C

9.20e-062106211870218
Pubmed

Phosphatidylinositol-3-kinase C2β and TRIM27 function to positively and negatively regulate IgE receptor activation of mast cells.

TRIM27 PIK3C2B

9.20e-062106222645315
Pubmed

Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

MYO5A MYO7B MYO5C

9.77e-061410638022818
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MAP1B MYO5A SPECC1 TFAM HNRNPH1 HNRNPH2 MYO5C ITPR2 BPTF SUPT6H AMOT PGRMC2 SYNE2

1.47e-0510241061324711643
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP4R1 CEP85 MYO5A LEMD3 XPO4 PTPN21 ITPR2 IWS1 PGRMC2 SYNE2 TRIM36 PLEKHA7 VBP1

1.89e-0510491061327880917
Pubmed

The DNA sequence and analysis of human chromosome 6.

ATG5 MMS22L FGD2 RANBP9 ANKRD6 TRIM27 NDUFAF4 AIG1 MED23 SH3BGRL2

2.13e-056221061014574404
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

CEP85 DNAH10 HNRNPH1 HNRNPH2 DNAJC14 SUPT6H SYNE2

2.35e-05277106730745168
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTB SPTBN4

2.76e-053106211294830
Pubmed

Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis.

AMOT AMOTL1

2.76e-053106219590046
Pubmed

Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2β.

TRIM27 PIK3C2B

2.76e-053106222128329
Pubmed

PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.

CCZ1B CCZ1

2.76e-053106232160108
Pubmed

Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains.

AMOT AMOTL1

2.76e-053106212406577
Pubmed

Differential expression of the motin family in the peri-implantation mouse uterus and their hormonal regulation.

AMOT AMOTL1

2.76e-053106222813598
Pubmed

Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.

MYO5A MYO5C

2.76e-053106224339992
Pubmed

hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.

HNRNPH1 HNRNPH2

2.76e-053106210456323
Pubmed

Structural insights into functional overlapping and differentiation among myosin V motors.

MYO5A MYO5C

2.76e-053106224097982
Pubmed

Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.

HNRNPH1 HNRNPH2

2.76e-053106214980514
Pubmed

The integrase cofactor LEDGF/p75 associates with Iws1 and Spt6 for postintegration silencing of HIV-1 gene expression in latently infected cells.

IWS1 SUPT6H

2.76e-053106225590759
Pubmed

The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre.

MAP1B RANBP9

2.76e-053106215381419
Pubmed

Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.

HNRNPH1 HNRNPH2

2.76e-053106221068389
Pubmed

Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity.

SPTB SPTBN4

2.76e-053106232052742
Pubmed

β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.

SPTB SPTBN4

2.76e-053106232425157
Pubmed

Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.

HNRNPH1 HNRNPH2

2.76e-05310627499401
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

GBP6 MAP1B RANBP9 MRPS35 SPECC1 HNRNPH1 HNRNPH2 ANAPC1 AMOT MAP7D2 ISG20L2

3.77e-058091061132129710
Pubmed

Vti1b promotes TRPV1 sensitization during inflammatory pain.

NDUFB10 HNRNPH1 HNRNPH2 COL14A1 TPT1P8

4.53e-05127106530335684
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CEP85 MAP1B BPTF ANAPC1 AMOT PGRMC2 AMOTL1 MED23 VBP1

4.82e-05549106938280479
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

XPO4 ZNF214 PTPN21 CDH19 TTC3 MAPKAPK5 AMOT ZNF566 TRIM36 DHX29

4.86e-056861061029987050
Pubmed

Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome.

GALNT14 GALNT3 GALNT16

5.32e-0524106331882545
Pubmed

Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.

GALNT14 GALNT3 GALNT16

5.32e-0524106331740596
Pubmed

Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.

MYO5A TRIM27 HNRNPH1 ANAPC1

5.39e-0567106429863498
Pubmed

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.

IWS1 SUPT6H

5.50e-054106219141475
Pubmed

The endothelial E3 ligase HECW2 promotes endothelial cell junctions by increasing AMOTL1 protein stability via K63-linked ubiquitination.

AMOT AMOTL1

5.50e-054106227498087
Pubmed

Angiomotin regulates endothelial cell migration during embryonic angiogenesis.

AMOT AMOTL1

5.50e-054106217699752
Pubmed

Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.

ITCH AMOT

5.50e-054106223564455
Pubmed

Alternative splicing in class V myosins determines association with Rab10.

MYO5A MYO5C

5.50e-054106219008234
Pubmed

Angiomotin-like proteins associate with and negatively regulate YAP1.

AMOT AMOTL1

5.50e-054106221187284
Pubmed

Gene-gene interaction of ATG5, ATG7, BLK and BANK1 in systemic lupus erythematosus.

ATG5 BANK1

5.50e-054106226420661
Pubmed

Angiomotin'g YAP into the nucleus for cell proliferation and cancer development.

AMOT AMOTL1

5.50e-054106224003252
Pubmed

Induction of autophagy in axonal dystrophy and degeneration.

ATG5 MAP1B

5.50e-054106216885219
Pubmed

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.

CCZ1B CCZ1

5.50e-054106220305638
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCP110 ITCH MAP1B PTPN21 SPECC1 GAB2 PIK3C2B AMOT SYNE2 CEP152 PLEKHA7

6.59e-058611061136931259
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

DNAJC21 TTC3 HNRNPH2 NBAS CDK5RAP3 ISG20L2

6.83e-05225106625277244
Pubmed

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.

MAP1B MYO5A SPECC1 TFAM HNRNPH1 MYO5C SH3BGRL2

6.83e-05328106723398456
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CCP110 CEP85 TRIM27 ANAPC1 AMOT AMOTL1 CEP152 PLEKHA7

6.92e-05446106824255178
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

CEP85 MAP1B MYO5A DHX37 DNAJC21 TRIM27 TTC3 ANAPC1 AMOT DHX29

7.60e-057241061036232890
Pubmed

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.

PGBD1 TFAM GAB2

8.53e-0528106320534741
Pubmed

Iws1 and Spt6 Regulate Trimethylation of Histone H3 on Lysine 36 through Akt Signaling and are Essential for Mouse Embryonic Genome Activation.

IWS1 SUPT6H

9.15e-055106230846735
Pubmed

Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.

NBAS TENM4

9.15e-055106223991058
Pubmed

The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation.

ITCH AMOT

9.15e-055106222385262
Pubmed

BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor.

ITPR2 BANK1

9.15e-055106211782428
Pubmed

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein.

AMOT AMOTL1

9.15e-055106221205866
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

LEMD3 ITPR2 NBAS NDUFAF4 CDK5RAP3 DNAJC14 PGRMC2 SYNE2

9.66e-05468106831056421
Pubmed

The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.

SECISBP2L PPP4R1 SYNE2

1.05e-0430106330480076
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MAP1B MYO5A DHX37 DNAJC21 TFAM HNRNPH1 BPTF ISG20L2 MED23 DHX29

1.12e-047591061035915203
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SLC12A6 MAP1B MYO5A SPTB SPECC1 TFAM HNRNPH1 ITPR2 SPTBN4 TENM4 AMOT MAP7D2 PLEKHA7 DHX29

1.15e-0414311061437142655
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ITCH MYO5A DHX37 MRPS35 DNAJC21 TRIM27 SPECC1 TFAM NDUFB10 HNRNPH1 HNRNPH2 ITPR2 AMOTL1

1.19e-0412571061336526897
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SLC12A6 MAP1B MYO5A DGKA MRPS35 DNAJC21 PTPN21 TTC3 TFAM SPTBN4 BPTF SYNE2 MAP7D2 ISG20L2

1.25e-0414421061435575683
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

MAP1B RANBP9 MRPS35 NDUFAF4 SUPT6H PGRMC2

1.30e-04253106629911972
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

MAP1B MYO5A SPTB SPECC1 TFAM HNRNPH1 ITPR2 ARHGAP4 SH3BGRL2

1.31e-04626106933644029
Pubmed

Angiomotin functions in HIV-1 assembly and budding.

AMOT AMOTL1

1.37e-046106225633977
Pubmed

Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.

AMOT AMOTL1

1.37e-046106217397395
Pubmed

Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases.

ITCH AMOT

1.37e-046106224101513
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SLC12A6 ITCH SPTB TTC3 SUPT6H AMOT SYNE2 COL14A1

1.46e-04497106823414517
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

SLC12A6 CCZ1B ITCH LEMD3 ITPR2 NBAS CDK5RAP3 SYNE2

1.60e-04504106834432599
Pubmed

Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability.

HNRNPH1 HNRNPH2 NDUFAF4 MAP7D2

1.63e-0489106431267705
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CEP85 LEMD3 MRPS35 TTC3 TFAM NDUFB10 ITPR2 NBAS NDUFAF4 CDK5RAP3 PGRMC2 SYNE2 ISG20L2 VBP1

1.83e-0414961061432877691
Pubmed

Galnt1 is required for normal heart valve development and cardiac function.

GALNT14 GALNT3 GALNT16

1.83e-0436106325615642
Pubmed

A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.

HNRNPH1 HNRNPH2

1.91e-047106231704785
Pubmed

Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.

HNRNPH1 HNRNPH2

1.91e-047106225846207
Pubmed

The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export.

IWS1 SUPT6H

1.91e-047106217234882
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RANBP9 HNRNPH1 HNRNPH2 ANAPC1 SUPT6H STAG3

1.92e-04272106631010829
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SECISBP2L CCP110 TCP11L1 RANBP9 XPO4 MRPS35 GAB2 NDUFAF4 AMOT PGRMC2 AMOTL1 COL14A1 PLEKHA7

1.94e-0413211061327173435
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

PPP4R1 CEP85 ITFG2 XPO4 COQ2 MAPKAPK5 IWS1 NBAS CDK5RAP3 DNAJC14 ANAPC1 PGRMC2 AIG1

2.03e-0413271061332694731
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

LEMD3 MRPS35 SPECC1 HNRNPH2 BPTF NDUFAF4 DHX29

2.18e-04396106726687479
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

ITCH SPTB NALCN SYNE2

2.36e-0498106434943047
Pubmed

O-glycosylation modulates integrin and FGF signalling by influencing the secretion of basement membrane components.

GALNT14 GALNT3 GALNT16

2.50e-0440106322643896
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

CCP110 CEP85 MAP7D2 CEP152

2.65e-04101106424613305
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

MAP1B LEMD3 MRPS35 DNAJC21 HNRNPH1 ARHGAP4 CDK5RAP3 VILL AMOTL1

2.66e-04689106936543142
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

DHX37 HNRNPH1 HNRNPH2 BPTF RCBTB1 INTS13 AMOT

2.73e-04411106735182466
Pubmed

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.

MAP1B MYO5A BPTF INTS13

2.75e-04102106426584622
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNAH10 SPTB HNRNPH1 SYNE2 CFAP44

2.78e-04187106526460568
Pubmed

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.

LEMD3 DEGS1 ITPR2 NBAS PGRMC2 SYNE2

3.19e-04299106637931956
Pubmed

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.

SPTBN4 TRIM36

3.27e-049106226671463
Pubmed

Large-scale analysis of the human ubiquitin-related proteome.

FGD2 RANBP9 MRPS35 TRIM27 HNRNPH1 AMOT

4.06e-04313106616196087
Pubmed

NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.

AMOT AMOTL1

4.08e-0410106233058421
Pubmed

Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures.

TFAM MMP13

4.08e-0410106235947192
Pubmed

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

CCZ1 MAP7D2

4.08e-0410106219413330
Pubmed

Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.

CHRNA6 CHRNB1

4.08e-0410106220736995
Pubmed

Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.

CEP85 CEP152 SH3BGRL2

4.31e-0448106327872092
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

USP17L1 MAP1B DHX37 TFAM HNRNPH1 HNRNPH2 IWS1 BPTF SUPT6H PGRMC2 MED23

4.72e-0410821061138697112
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CCZ1B KBTBD8 DGKA ANKRD6 TTC3 CDK5RAP3 VILL CCZ1 INTS13 AMOT PLEKHA7

4.80e-0410841061111544199
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

DHX37 ITPR2 ANAPC1 SUPT6H MAP7D2

4.94e-04212106533853758
Cytoband11q14.3

TRIM64 TRIM64B AMOTL1

5.65e-0532106311q14.3
Cytoband12p11

MRPS35 ITPR2

1.88e-049106212p11
Cytoband15q21

MYO5A MYO5C

2.87e-0411106215q21
CytobandEnsembl 112 genes in cytogenetic band chr11q14

TRIM64 GAB2 TRIM64B TENM4

4.87e-041561064chr11q14
CytobandEnsembl 112 genes in cytogenetic band chr15q21

SECISBP2L MYO5A MYO5C CEP152

7.81e-041771064chr15q21
Cytoband6q16.1

MMS22L NDUFAF4

7.89e-041810626q16.1
CytobandEnsembl 112 genes in cytogenetic band chr12p11

MRPS35 ITPR2 INTS13

1.03e-03851063chr12p11
Cytoband12q24.13

MAPKAPK5 TPCN1

1.53e-0325106212q24.13
GeneFamilyMyosins, class V

MYO5A MYO5C

5.08e-0537521100
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNT14 GALNT3 GALNT16

7.43e-0520753433
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN4

3.52e-0477521113
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM64 TRIM27 TRIM64B TRIM36

6.54e-049575459
GeneFamilyRing finger proteins

TRIM64 TRIM27 TTC3 TRIM64B RNF103 TRIM36

9.81e-0427575658
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD2 SPTB GAB2 SPTBN4 PLEKHA7

1.65e-03206755682
GeneFamilyCholinergic receptors nicotinic subunits

CHRNA6 CHRNB1

1.96e-0316752173
GeneFamilyDEAH-box helicases

DHX37 DHX29

1.96e-0316752500
GeneFamilyDyneins, axonemal

DNAH10 DNAH1

2.22e-0317752536
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 GALNT14 MYO7B ABCC6 TPCN1 TINAG SYNE2

3.30e-071871067dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 GALNT14 MYO7B ABCC6 TPCN1 TINAG SYNE2

3.30e-071871067f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B MYO5A SPTB TTC3 SPTBN4 FAT2 KCNT1

3.54e-071891067f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN21 ANKRD6 CHRNB1 SPTBN4 TINAG MAP7D2

1.95e-061551066cd2f3ad4f131588325a667b6724e530d821fbe30
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN21 ANKRD6 CHRNB1 SPTBN4 TINAG MAP7D2

1.95e-0615510669b26ade19488511c72b64335011d2dcd81e8f167
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN21 ANKRD6 CHRNB1 SPTBN4 TINAG MAP7D2

1.95e-0615510664246709e27703b94529369abbed5763e4002e79d
ToppCellAdult-Mesenchymal-myofibroblast_cell-D175|Adult / Lineage, Cell type, age group and donor

GALNT14 SPTBN4 NALCN PGRMC2 COL14A1 STAG3

2.43e-061611066048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 GALNT14 MYO7B TINAG TENM4 SYNE2

5.24e-0618410669434731f651820b05335085582960f08fbf895de
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 GALNT14 MYO7B ABCC6 TINAG PLEKHA7

5.93e-061881066f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 GALNT14 MYO7B ABCC6 TINAG PLEKHA7

5.93e-0618810660792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 MYO7B ABCC6 TINAG SYNE2 PLEKHA7

6.49e-0619110663c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 MYO7B ABCC6 TINAG SYNE2 PLEKHA7

6.49e-0619110661c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B MYO5A SPTB TTC3 FAT2 KCNT1

6.89e-0619310665fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

TTC3 SPECC1 IWS1 BPTF SYNE2 DHX29

7.97e-06198106676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

DNAJC21 TTC3 SPECC1 BPTF PGRMC2 SYNE2

8.20e-06199106618a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

MAP1B DNAJC21 TTC3 SPECC1 BPTF SYNE2

8.20e-061991066c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

DNAJC21 TTC3 SPECC1 BPTF SYNE2 DHX29

8.20e-061991066a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

MAP1B MYO5A TTC3 SPTBN4 MAP7D2 KCNT1

8.44e-062001066c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B PTPN21 SPECC1 RCBTB1 AMOTL1

2.21e-051411065dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT3 DNAH10 GAB2 TENM4 BANK1

4.43e-0516310658dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT3 DNAH10 GAB2 TENM4 BANK1

4.43e-051631065fd243ca223079033be480a24817a399f281fa4d4
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

MAP1B SPTB CDH19 GALNT16 COL14A1

5.71e-051721065c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMS22L GALNT3 FGD2 VILL CEP152

6.20e-0517510653bca1aac2a2a1f46753b5f9462888f144ed8327b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B ABCC6 TINAG SYNE2 AIG1

7.27e-0518110659542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B ABCC6 TINAG SYNE2 AIG1

7.27e-0518110658f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MAP1B SPTB GALNT16 COL14A1 KCNT1

7.47e-05182106546c213597445b1f4f09dc367f27702d24b201daf
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT14 MYO7B TINAG SYNE2 PLEKHA7

7.66e-0518310656878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A6 MYO7B ABCC6 TPCN1 TINAG

7.66e-05183106584b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT14 FGD2 MAP1B ANKRD6 KCNT1

7.86e-0518410653da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

MYO5A ANKRD6 ITPR2 NALCN COL14A1

7.86e-05184106567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 DNAH10 DNAH1 CFAP44 PLEKHA7

8.06e-05185106505bc89a566b0db90ae06506e067190a4739a0974
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATRN FGD2 MYO5A ITPR2 TPCN1

8.06e-0518510658207f9eff113eed429e961748c6b17d672a13b33
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SPTB TTC3 FAT2 KCNT1

8.27e-051861065d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellBL-critical-LOC-Lymphoid-B_cell|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FGD2 KBTBD8 PIK3C2B STAG3 BANK1

8.27e-05186106527d4c38b180e4ce2bf3e7c4ad3db3a2ffca05ca8
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATRN ITFG2 ABCC6 ITPR2 AIG1

8.48e-051871065f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SECISBP2L CHRNA6 TRIM27 ITPR2 DNAJC14

8.48e-051871065816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC21 COQ2 TFAM TINAG NDUFAF4

9.14e-05190106536e83995021ba16690f84e2077a9e8baec547d05
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP1B HNRNPH1 BPTF AMOTL1 BANK1

9.14e-051901065d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC21 COQ2 TFAM TINAG NDUFAF4

9.14e-051901065d26be9e1b676f750e716b91ebc3598fac3735612
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L DNAJC21 SPECC1 ITPR2 SYNE2

9.37e-05191106560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

MAP1B SPTB GALNT16 COL14A1 KCNT1

9.37e-051911065fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L DNAJC21 SPECC1 SYNE2 SH3BGRL2

9.37e-05191106509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L DNAJC21 SPECC1 ITPR2 SYNE2

9.37e-051911065973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell10x5'-bone_marrow-Lymphocytic_B-Naive_B_cells|bone_marrow / Manually curated celltypes from each tissue

FGD2 MYO7B PIK3C2B STAG3 BANK1

9.60e-051921065fa99243ff028498c6a67d207a93e02c48e69cd42
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MAP1B MYO5A TTC3 SPTBN4 MAP7D2

9.84e-051931065b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGD2 MYO7B BPTF STAG3 BANK1

1.01e-041941065ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAP1B MYO5A TTC3 SPTBN4 MAP7D2

1.01e-0419410658aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell(6)_Endothelial_cells-(6)_Endothelial-B_(Artery)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CPAMD8 MYO7B ARHGAP4 PIK3C2B PGRMC2

1.06e-041961065f540cf17b4405a6dd38d2b6123e6541d0aac889e
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGD2 MYO5A ITPR2 TPCN1 ARHGAP4

1.08e-04197106510190b877bf46ba2163d203df9dd3b498c66e52f
ToppCelldistal-Endothelial-Bronchial_Vessel_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GALNT14 CPAMD8 MYO5C PIK3C2B SH3BGRL2

1.08e-0419710659fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1
ToppCelldistal-3-Endothelial-Bronchial_Vessel_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GALNT14 CPAMD8 MYO5C PIK3C2B SH3BGRL2

1.11e-041981065f701d06e3d7fd2192afae3698c5ec3c355e96da3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

SLC12A6 RANBP9 SPECC1 NBAS CEP152

1.14e-041991065fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

SLC12A6 RANBP9 SPECC1 NBAS CEP152

1.14e-04199106591882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

SLC12A6 RANBP9 HNRNPH1 NBAS CEP152

1.16e-042001065d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell|GW13 / Sample Type, Dataset, Time_group, and Cell type.

SLC12A6 RANBP9 HNRNPH1 NBAS CEP152

1.16e-0420010653d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

MAP1B SPECC1 ARHGAP4 PIK3C2B SYNE2

1.16e-04200106565b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP1B SPTB GALNT16 COL14A1 KCNT1

1.16e-042001065c1d9748aaae489d26e24602a5dcbe7f5fa9a5548
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GALNT14 FAT2 TENM4 VILL MMP13

1.16e-0420010658827653738a931e4a4545e0c7d75be12bed40740
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP1B SPTB GALNT16 COL14A1 KCNT1

1.16e-0420010656a5047018b12be3bc4b55a64d42e52e96c624003
ToppCellmedial-2-mesenchymal-Airway_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP1B SPTB GALNT16 COL14A1 KCNT1

1.16e-04200106516b00eacbea4d75cf814803d3fc0b82c2b8c0a9c
ToppCellBronchus_Control_(B.)-Immune-TX-DCs|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ADGRG5 FGD2 KBTBD8 ITPR2 ARHGAP4

1.16e-042001065e0beacb88bbdc353a3e883171613027feafcf1ef
ComputationalGenes in the cancer module 119.

DGKA DNAJC14 PIK3C2B SYNE2 STAG3 BANK1

1.38e-04143606MODULE_119
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN4

6.79e-0541002DOID:0050882 (implicated_via_orthology)
Diseasepalmitoyl dihydrosphingomyelin (d18:0/16:0) measurement

DEGS1 SYNE2

2.36e-0471002EFO_0800400
Diseaseinterventricular septum thickness

ITPR2 INTS13

5.03e-04101002EFO_0009287
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

DNAH10 DNAH1 BPTF SYNE2 BANK1

6.95e-042061005EFO_0004612, EFO_0020947
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

LEMD3 SYNE2

7.34e-04121002DOID:11726 (implicated_via_orthology)
Diseasetrimethylamine-N-oxide measurement

ITPR2 INTS13

1.01e-03141002EFO_0010541
DiseaseHermansky-Pudlak syndrome (implicated_via_orthology)

CCZ1B CCZ1

1.01e-03141002DOID:3753 (implicated_via_orthology)
Diseasepyroglutamine measurement

MYO5A ANKRD6 CDK5RAP3

1.02e-03581003EFO_0005408
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRNA6 CHRNB1

1.32e-03161002DOID:3635 (implicated_via_orthology)
Diseasenon-small cell lung carcinoma

SECISBP2L BPTF NALCN

2.14e-03751003EFO_0003060
DiseaseQRS duration, response to sulfonylurea

COQ2 TINAG

2.75e-03231002EFO_0005055, EFO_0007922
Diseasereticulocyte count

ATRN CCZ1B DNAH10 SPTB KBTBD8 SPECC1 SYNE2 MMP13 PLEKHA7 AFG1L

2.89e-03104510010EFO_0007986
Diseasereticulocyte measurement

ATRN CCZ1B DNAH10 SPTB KBTBD8 SPECC1 GAB2 SYNE2 PLEKHA7 AFG1L

3.06e-03105310010EFO_0010700
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

DNAH10 BPTF TENM4 SYNE2 BANK1

3.17e-032911005EFO_0008317, EFO_0020946
Diseasecognitive function measurement

ATG5 PPP4R1 GALNT14 MMS22L GALNT3 XPO4 CDH19 GALNT16 CHRNB1 TENM4 TRIM36 AFG1L

3.35e-03143410012EFO_0008354

Protein segments in the cluster

PeptideGeneStartEntry
TKDIIMIYEEDAEEW

BANK1

26

Q8NDB2
ADMTKWEQKYLEENV

AMOT

676

Q4VCS5
CMEVQKIRYVWNDLE

ATP13A5

131

Q4VNC0
EWTMQEAKRIQLEIY

CEP152

1026

O94986
VLNNYIWDTQKSMEE

AIG1

216

Q9NVV5
ISRLTEMQTEQYWNE

AFG1L

461

Q8WV93
TKQMKEETEEWRRFQ

SPECC1

711

Q5M775
EEMSTKVYLDLEWTD

CHRNB1

71

P11230
EADMTKWEQKYLEES

AMOTL1

681

Q8IY63
FQKVMRQEDISEIWF

ATG5

56

Q9H1Y0
EVNMKEWILRYAEQQ

DHX29

226

Q7Z478
QEEEETMQQATWVKY

BPTF

996

Q12830
SLDKEEQYMQWKINE

CFAP44

1431

Q96MT7
STQMEKWYERKIEEA

ANKRD6

676

Q9Y2G4
NTKRTAEVWMDEYKQ

GALNT16

366

Q8N428
FDIEDYMREWRTKIQ

RANBP9

336

Q96S59
SYWNEDMKEVIEIDQ

RCBTB1

401

Q8NDN9
DYVVRPKWNVEMESS

IWS1

761

Q96ST2
ESYVAQMIVEKNLDW

ITPR2

2611

Q14571
DEQYRIMWNELETLV

INTS13

526

Q9NVM9
WTKEEEETRQMYDMV

LEMD3

656

Q9Y2U8
TQWYEQTKEELMAPT

ANAPC1

1641

Q9H1A4
DMWDQDYDKKVTRTA

COQ2

131

Q96H96
WDIVSNAEKRKEYEM

DNAJC14

491

Q6Y2X3
SEVMREWYQETHEKQ

MAP1B

2426

P46821
EDEKLNEVMQEAWKY

MAPKAPK5

411

Q8IW41
QYEKQMEERWRKLEE

MAP7D2

86

Q96T17
DEMRKVESNWNFVEE

MMS22L

371

Q6ZRQ5
RYDVDTQMWTILKDS

ATRN

536

O75882
QFEELVYLWMERQKS

KCNT1

326

Q5JUK3
RYVEVFKSNSVEMDW

HNRNPH2

81

P55795
TTEVNMARVYNWDVK

VBP1

171

P61758
EFSLVSVKDINWMEY

FAT2

311

Q9NYQ8
QVWRYDDTNHIMDKD

MMP13

401

P45452
ESVREWEMQFKEKYD

PGRMC2

181

O15173
EAEMQWKRDYKVDQE

NDUFB10

81

O96000
EEEYRKWKSMSNEND

MED23

761

Q9ULK4
QMMRVAEYLDWDVSE

DGKA

141

P23743
TMELYKLVEVEWEEH

ISG20L2

331

Q9H9L3
METKERIEQDYWQVP

GBP6

436

Q6ZN66
RYVEVFKSNNVEMDW

HNRNPH1

81

P31943
QAKLVEQYREQSWMT

DNAJC21

246

Q5F1R6
KVMDWYQTRAEEIEH

NBAS

841

A2RRP1
YWEVQLERMESTNLV

ITFG2

381

Q969R8
MFTVEAYDIELNKWT

KBTBD8

496

Q8NFY9
QFQTEDMETAKYIWR

PTPN21

281

Q16825
DIMQKESLYWLTDAD

PIK3C2B

821

O00750
YIKNTKRTAEVWMDE

GALNT14

351

Q96FL9
EENKEEYIRMVAEWR

ITCH

731

Q96J02
YAIEQALDKMEKEWS

DNAH1

1156

Q9P2D7
EVEDDWKYVAMVVDR

CHRNA6

451

Q15825
LYDVTENSMRVKWDA

COL14A1

451

Q05707
QVRLAEVWMDEYKEI

GALNT3

436

Q14435
SQRMKDWQEIIALYE

CDK5RAP3

91

Q96JB5
EFRIWRKMEVDESYS

CPAMD8

1086

Q8IZJ3
DEEIIVKAMSDYWVV

CCZ1

426

P86791
EVEMESWQKRYDSLQ

CEP85

566

Q6P2H3
DEEIIVKAMSDYWVV

CCZ1B

426

P86790
NSWIKVLYDFVMDDT

DEGS1

291

O15121
DQWEMETVYSNSEVR

CCP110

101

O43303
ITEMERLQDLWEVYQ

FGD2

291

Q7Z6J4
YKNETEWRANIDTVM

ENPP7

166

Q6UWV6
VQSEEMLEDKWRNAY

DHX37

941

Q8IY37
KEYEDRKYEQWMEVT

DNAH10

616

Q8IVF4
VNVENWDNKSYMTDI

RNF103

266

O00237
EETETYQEKVHMTWT

SLC12A6

1036

Q9UHW9
KMDRELQDEYWVIIQ

CDH19

211

Q9H159
YLVAETEEDMNKWVQ

GAB2

96

Q9UQC2
TEYRQVKQVSMVDRW

MEIG1

36

Q5JSS6
KSKTEADMEEYIWEN

MRPS35

241

P82673
QWLEEASEDLMTQKY

TCP11L1

266

Q9NUJ3
QMEREKIVWEFEQLY

TRIM27

176

P14373
EYRKINRDDEMSWNE

TRIM36

451

Q9NQ86
ETYETLASDMQWKVR

PPP4R1

666

Q8TF05
LQEVYKLEDVLDSMW

SYNE2

4706

Q8WXH0
VSVERMQDYAWTPKE

ABCC6

1231

O95255
RESTEMENAWNEYLK

PLEKHA7

766

Q6IQ23
EKEYETNWRNMVETS

SECISBP2L

871

Q93073
ETWTAEKIMQEYQLE

NDUFAF4

131

Q9P032
EMYWEVSDTDQNLVR

PGBD1

476

Q96JS3
YHNEMKSWEEQMIEV

TFAM

211

Q00059
EYETQVKEMRWQLSE

ARHGAP4

16

P98171
NEMFSDIYKIWEITN

TPT1P8

11

Q9HAU6
TETWEELLSYMENMQ

ADGRG5

21

Q8IZF4
ETYEWARKMAVDALE

SUPT6H

1061

Q7KZ85
AHMDTETKQQYWTEV

XPO4

761

Q9C0E2
MQSLVDEWLDSYKQD

STAG3

111

Q9UJ98
NWRETDEYSAEMKQF

THAP9

201

Q9H5L6
EVDITMSEEQRQWMY

SH3BGRL2

36

Q9UJC5
MKEYLEAVSVQELWE

TTC41P

556

Q6P2S7
ENWKESEVYKLQIME

TTC3

1646

P53804
YELIHTQMKTQEWDN

TENM4

2501

Q6N022
KLQSMESQVEEWYRE

SPTBN4

1451

Q9H254
MDEAESWIKEKEQIY

SPTB

646

P11277
AQEVQWYKMDDAEVT

USP17L1

341

Q7RTZ2
EEFYSMATWRQRQEK

VILL

836

O15195
SDLSLKMYQEEIQEW

TPCN1

766

Q9ULQ1
KKEIYEIESTQWEIM

ZNF566

91

Q969W8
EIWMEKQYLSQREVD

TINAG

16

Q9UJW2
KEMDYLWEINQETRN

TRIM64

141

A6NGJ6
KEMDYLWEINQETRN

TRIM64B

141

A6NI03
DSSQKRLYREVMWEN

ZNF214

21

Q9UL59
YTIEEEVAKQTIRMW

NALCN

1561

Q8IZF0
KLEQEEYMKEQIPWT

MYO5A

471

Q9Y4I1
EQEEYMKEDIPWTLI

MYO5C

471

Q9NQX4
TMEQEEYRSENISWD

MYO7B

471

Q6PIF6