Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR4M2 TAS2R4 TAS2R9 DRD1 DRD2 OR5AC1 DRD5 ADRB2 ADRB3 OR2AT4 TAS2R33 OR4A16 OR5L1 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 OR1F2P TACR2 OR8U3 CALCRL OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 GRM6 OR5AR1 CHRM4 GRPR OR51B2 OR4M2B OR8B3 OR4D2	1.81e-30	884	65	35	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR4M2 TAS2R4 TAS2R9 DRD1 DRD2 OR5AC1 DRD5 ADRB2 ADRB3 OR2AT4 TAS2R33 OR4A16 OR5L1 GLRA2 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 OR1F2P TACR2 OR8U3 CALCRL OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 GRM6 OR5AR1 CHRM4 GRPR OR51B2 OR4M2B OR8B3 OR4D2	1.94e-25	1353	65	36	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	3.61e-18	431	65	20	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR5AC1 OR5L1 OR5B17 OR8U3 OR5M8 OR8B2 OR8D4 OR5AR1 OR8B3	3.03e-10	127	65	9	GO:0005549
GeneOntologyMolecularFunction	catecholamine binding	DRD1 DRD2 DRD5 ADRB2 ADRB3	3.94e-10	13	65	5	GO:1901338
GeneOntologyMolecularFunction	dopamine neurotransmitter receptor activity	DRD1 DRD2 DRD5	3.28e-07	5	65	3	GO:0004952
GeneOntologyMolecularFunction	transporter activity	SLC6A1 SLC6A2 LRRC8E LRRC8C GPR89B SLC9A4 SLC9A1 ABCA12 ABCA13 GLRA2 GPR89A SLC36A3 ATP13A3 ATP9A LMBRD1 SLC35A5 KCNH5	5.10e-07	1289	65	17	GO:0005215
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A1 SLC6A2 LRRC8E LRRC8C GPR89B GLRA2 GPR89A	5.93e-07	151	65	7	GO:0008509
GeneOntologyMolecularFunction	dopamine binding	DRD1 DRD2 DRD5	1.14e-06	7	65	3	GO:0035240
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A1 SLC6A2 LRRC8E LRRC8C GPR89B SLC9A4 SLC9A1 ABCA12 ABCA13 GLRA2 GPR89A SLC36A3 ATP13A3 SLC35A5 KCNH5	4.34e-06	1180	65	15	GO:0022857
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	DRD1 DRD2 DRD5 GLRA2 CHRM4	4.52e-06	75	65	5	GO:0098960
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A1 SLC6A2 LRRC8E LRRC8C GPR89B SLC9A4 SLC9A1 GLRA2 GPR89A SLC36A3 ATP13A3 KCNH5	8.22e-06	793	65	12	GO:0015075
GeneOntologyMolecularFunction	dopamine neurotransmitter receptor activity, coupled via Gs	DRD1 DRD5	1.04e-05	2	65	2	GO:0001588
GeneOntologyMolecularFunction	G-protein alpha-subunit binding	DRD1 DRD2 DRD5 ADRB2	1.15e-05	43	65	4	GO:0001965
GeneOntologyMolecularFunction	neurotransmitter receptor activity	DRD1 DRD2 DRD5 GLRA2 CHRM4	1.85e-05	100	65	5	GO:0030594
GeneOntologyMolecularFunction	monoatomic anion channel activity	LRRC8E LRRC8C GPR89B GLRA2 GPR89A	2.14e-05	103	65	5	GO:0005253
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A1 SLC6A2 SLC9A4 SLC9A1 ABCA12 ABCA13 SLC36A3 ATP13A3 SLC35A5	2.29e-05	477	65	9	GO:0022804
GeneOntologyMolecularFunction	bradykinin receptor binding	ADRB2 AGTR1	3.12e-05	3	65	2	GO:0031711
GeneOntologyMolecularFunction	norepinephrine binding	ADRB2 ADRB3	6.23e-05	4	65	2	GO:0051380
GeneOntologyMolecularFunction	beta-adrenergic receptor activity	ADRB2 ADRB3	6.23e-05	4	65	2	GO:0004939
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	AGTR1 NPSR1 TACR2 CALCRL GRPR	7.29e-05	133	65	5	GO:0008528
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R4 TAS2R9 TAS2R33	9.11e-05	27	65	3	GO:0033038
GeneOntologyMolecularFunction	peptide receptor activity	AGTR1 NPSR1 TACR2 CALCRL GRPR	9.29e-05	140	65	5	GO:0001653
GeneOntologyMolecularFunction	taste receptor activity	TAS2R4 TAS2R9 TAS2R33	1.68e-04	33	65	3	GO:0008527
GeneOntologyMolecularFunction	G protein-coupled amine receptor activity	ADRB2 ADRB3 CHRM4	3.21e-04	41	65	3	GO:0008227
GeneOntologyMolecularFunction	heterotrimeric G-protein binding	DRD1 DRD2	3.70e-04	9	65	2	GO:0032795
GeneOntologyMolecularFunction	volume-sensitive anion channel activity	LRRC8E LRRC8C	3.70e-04	9	65	2	GO:0005225
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A1 SLC6A2 SLC9A4 SLC9A1 SLC36A3 SLC35A5	4.00e-04	296	65	6	GO:0015291
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC6A1 SLC6A2 SLC9A4 SLC9A1 SLC36A3 ATP13A3	4.37e-04	301	65	6	GO:0022853
GeneOntologyMolecularFunction	adrenergic receptor activity	ADRB2 ADRB3	4.62e-04	10	65	2	GO:0004935
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA12 ABCA13 ATP13A3	5.45e-04	49	65	3	GO:0140359
GeneOntologyMolecularFunction	neuropeptide receptor activity	NPSR1 TACR2 GRPR	6.87e-04	53	65	3	GO:0008188
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9A4 SLC9A1	9.26e-04	14	65	2	GO:0015386
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9A4 SLC9A1	1.22e-03	16	65	2	GO:0015385
GeneOntologyMolecularFunction	sodium:chloride symporter activity	SLC6A1 SLC6A2	1.37e-03	17	65	2	GO:0015378
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	GPR89B GPR89A	1.37e-03	17	65	2	GO:0008308
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A1 SLC6A2	1.72e-03	19	65	2	GO:0015373
GeneOntologyMolecularFunction	solute:potassium antiporter activity	SLC9A4 SLC9A1	1.72e-03	19	65	2	GO:0022821
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A1 SLC6A2 SLC9A4 SLC9A1	2.34e-03	171	65	4	GO:0015081
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC6A2 SLC36A3 ATP13A3	2.51e-03	83	65	3	GO:0015101
GeneOntologyMolecularFunction	chloride:monoatomic cation symporter activity	SLC6A1 SLC6A2	2.53e-03	23	65	2	GO:0015377
GeneOntologyMolecularFunction	dopamine receptor binding	DRD1 AGTR1	3.22e-03	26	65	2	GO:0050780
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A1 SLC6A2	3.22e-03	26	65	2	GO:0015296
GeneOntologyMolecularFunction	metal cation:proton antiporter activity	SLC9A4 SLC9A1	3.47e-03	27	65	2	GO:0051139
GeneOntologyMolecularFunction	mannosyltransferase activity	PIGB DPY19L2P2	3.73e-03	28	65	2	GO:0000030
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA12 ATP9A	3.73e-03	28	65	2	GO:0140326
GeneOntologyMolecularFunction	monoatomic ion channel activity	LRRC8E LRRC8C GPR89B GLRA2 GPR89A KCNH5	3.75e-03	459	65	6	GO:0005216
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC6A1 SLC36A3	4.00e-03	29	65	2	GO:0005416
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA12 ABCA13 ATP13A3	5.41e-03	109	65	3	GO:0042626
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A1 SLC6A2 SLC9A4 SLC9A1 SLC36A3 ATP13A3 KCNH5	5.71e-03	664	65	7	GO:0008324
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A1 SLC6A2 SLC36A3	6.89e-03	119	65	3	GO:0015294
GeneOntologyMolecularFunction	channel activity	LRRC8E LRRC8C GPR89B GLRA2 GPR89A KCNH5	7.15e-03	525	65	6	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	LRRC8E LRRC8C GPR89B GLRA2 GPR89A KCNH5	7.21e-03	526	65	6	GO:0022803
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A1 SLC6A2 GLRA2	7.89e-03	125	65	3	GO:0015108
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC9A4 SLC9A1	8.65e-03	43	65	2	GO:0140828
GeneOntologyMolecularFunction	antiporter activity	SLC9A4 SLC9A1 SLC35A5	1.03e-02	138	65	3	GO:0015297
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A1 SLC6A2 SLC9A4 SLC9A1 GLRA2 SLC36A3 KCNH5	1.14e-02	758	65	7	GO:0015318
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ABCA12 ATP9A	1.20e-02	51	65	2	GO:0140303
GeneOntologyMolecularFunction	ionotropic glutamate receptor binding	DRD2 ADRB2	1.25e-02	52	65	2	GO:0035255
GeneOntologyMolecularFunction	symporter activity	SLC6A1 SLC6A2 SLC36A3	1.29e-02	150	65	3	GO:0015293
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC6A1 SLC6A2 SLC9A4 SLC9A1 SLC36A3 KCNH5	1.61e-02	627	65	6	GO:0022890
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR4M2 TAS2R4 TAS2R9 DRD1 DRD2 OR5AC1 DRD5 ADRB2 ADRB3 OR2AT4 TAS2R33 OR4A16 OR5L1 GLRA2 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 OR1F2P TACR2 OR8U3 CALCRL OR2T10 LMBRD2 OR5M8 OR13C7 OR8B2 OR8D4 GRM6 OR5AR1 CHRM4 GRPR ADCY6 OR51B2 OR4M2B OR8B3 OR4D2	5.28e-28	1395	65	38	GO:0007186
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR4M2 TAS2R4 TAS2R9 DRD2 OR5AC1 OR2AT4 TAS2R33 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	1.29e-21	547	65	24	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR4M2 TAS2R4 TAS2R9 OR5AC1 OR2AT4 TAS2R33 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	1.89e-21	485	65	23	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR4M2 TAS2R4 TAS2R9 OR5AC1 OR2AT4 TAS2R33 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 GRM6 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	5.49e-21	582	65	24	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR4M2 TAS2R4 TAS2R9 OR5AC1 OR2AT4 TAS2R33 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	1.08e-20	524	65	23	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of smell	OR4M2 DRD2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	4.03e-19	465	65	21	GO:0007608
GeneOntologyBiologicalProcess	detection of stimulus	OR4M2 TAS2R4 TAS2R9 OR5AC1 OR2AT4 TAS2R33 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 GRM6 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	8.08e-19	722	65	24	GO:0051606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	2.03e-18	432	65	20	GO:0050911
GeneOntologyBiologicalProcess	sensory perception	OR4M2 TAS2R4 TAS2R9 DRD2 OR5AC1 OR2AT4 TAS2R33 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR13C7 OR8B2 OR8D4 GRM6 OR5AR1 OR51B2 OR4M2B OR8B3 OR4D2	5.28e-16	1072	65	25	GO:0007600
GeneOntologyBiologicalProcess	adrenergic receptor signaling pathway	DRD1 DRD2 DRD5 ADRB2 ADRB3 LMBRD2	1.17e-09	35	65	6	GO:0071875
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	OR4M2 DRD1 DRD2 DRD5 ADRB2 ADRB3 OR4M1 CALCRL GRM6 CHRM4 ADCY6	1.39e-09	286	65	11	GO:0007188
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC6A1 SLC6A2 LRRC8E LRRC8C GPR89B SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 GLRA2 AGTR1 NPSR1 GPR89A SLC36A3 TACR2 ATP13A3 CALCRL GRM6 KCNH5	4.05e-09	1374	65	20	GO:0006811
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC6A1 SLC6A2 LRRC8E LRRC8C GPR89B SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 GLRA2 AGTR1 NPSR1 GPR89A SLC36A3 ATP13A3 GRM6 KCNH5	6.01e-09	1115	65	18	GO:0034220
GeneOntologyBiologicalProcess	adenylate cyclase-activating G protein-coupled receptor signaling pathway	OR4M2 DRD1 DRD2 DRD5 ADRB2 ADRB3 OR4M1 CALCRL ADCY6	8.47e-09	191	65	9	GO:0007189
GeneOntologyBiologicalProcess	adenylate cyclase-activating adrenergic receptor signaling pathway	DRD1 DRD2 DRD5 ADRB2 ADRB3	1.34e-08	25	65	5	GO:0071880
GeneOntologyBiologicalProcess	import into cell	SLC6A1 SLC6A2 LRRC8E LRRC8C SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 ADRB3 ABCA13 AGTR1 CALCRL ATP9A GRM6 LMBRD1	1.52e-07	1074	65	16	GO:0098657
GeneOntologyBiologicalProcess	import across plasma membrane	SLC6A1 LRRC8E LRRC8C SLC9A4 SLC9A1 ADRB2 AGTR1 GRM6	6.18e-07	230	65	8	GO:0098739
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	DRD1 DRD2 DRD5 ADRB2 ADRB3	1.17e-06	59	65	5	GO:0045761
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport	SLC9A1 DRD1 ADRB2 AGTR1 NPSR1 GRM6	1.22e-06	109	65	6	GO:1904427
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	DRD5 ADRB2 ADRB3	1.65e-06	8	65	3	GO:0001993
GeneOntologyBiologicalProcess	phospholipase C-activating dopamine receptor signaling pathway	DRD1 DRD2 DRD5	2.48e-06	9	65	3	GO:0060158
GeneOntologyBiologicalProcess	regulation of cyclase activity	DRD1 DRD2 DRD5 ADRB2 ADRB3	2.56e-06	69	65	5	GO:0031279
GeneOntologyBiologicalProcess	regulation of lyase activity	DRD1 DRD2 DRD5 ADRB2 ADRB3	3.38e-06	73	65	5	GO:0051339
GeneOntologyBiologicalProcess	response to catecholamine	DRD1 DRD2 DRD5 ADRB2 ADCY6	3.38e-06	73	65	5	GO:0071869
GeneOntologyBiologicalProcess	response to monoamine	DRD1 DRD2 DRD5 ADRB2 ADCY6	3.62e-06	74	65	5	GO:0071867
GeneOntologyBiologicalProcess	activation of adenylate cyclase activity	DRD1 DRD5 ADRB2 ADRB3	3.88e-06	34	65	4	GO:0007190
GeneOntologyBiologicalProcess	synaptic transmission, dopaminergic	SLC6A2 DRD1 DRD2 DRD5	4.37e-06	35	65	4	GO:0001963
GeneOntologyBiologicalProcess	regulation of calcium ion transmembrane transport	SLC9A1 DRD1 DRD2 ADRB2 AGTR1 NPSR1 GRM6	5.54e-06	218	65	7	GO:1903169
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	SLC6A1 SLC9A4 SLC9A1 ADRB2 AGTR1 GRM6	5.66e-06	142	65	6	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	SLC6A1 SLC9A4 SLC9A1 ADRB2 AGTR1 GRM6	5.66e-06	142	65	6	GO:0098659
GeneOntologyBiologicalProcess	neurotransmitter reuptake	SLC6A1 SLC6A2 DRD1 DRD2	6.12e-06	38	65	4	GO:0098810
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC6A1 SLC6A2 SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 AGTR1 NPSR1 SLC36A3 ATP13A3 GRM6 KCNH5	6.25e-06	942	65	13	GO:0098655
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	DRD1 DRD5 ADRB2 ADRB3	7.54e-06	40	65	4	GO:0045762
GeneOntologyBiologicalProcess	positive regulation of calcium ion import across plasma membrane	ADRB2 AGTR1 GRM6	8.35e-06	13	65	3	GO:1905665
GeneOntologyBiologicalProcess	regulation of excretion	DRD2 AGTR1 NPSR1	8.35e-06	13	65	3	GO:0044062
GeneOntologyBiologicalProcess	dopamine uptake involved in synaptic transmission	SLC6A2 DRD1 DRD2	8.35e-06	13	65	3	GO:0051583
GeneOntologyBiologicalProcess	catecholamine uptake involved in synaptic transmission	SLC6A2 DRD1 DRD2	8.35e-06	13	65	3	GO:0051934
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	SLC6A1 LRRC8E LRRC8C GPR89B GLRA2 GPR89A	8.69e-06	153	65	6	GO:0098656
GeneOntologyBiologicalProcess	positive regulation of calcium ion transport	SLC9A1 DRD1 ADRB2 AGTR1 NPSR1 GRM6	9.02e-06	154	65	6	GO:0051928
GeneOntologyBiologicalProcess	G protein-coupled dopamine receptor signaling pathway	DRD1 DRD2 DRD5 ADCY6	1.11e-05	44	65	4	GO:0007212
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC6A1 SLC6A2 SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 AGTR1 NPSR1 SLC36A3 ATP13A3 CALCRL GRM6 KCNH5	1.17e-05	1157	65	14	GO:0006812
GeneOntologyBiologicalProcess	vascular process in circulatory system	SLC6A1 DRD1 DRD5 ADRB2 ADRB3 AGTR1 TACR2 ADCY6	1.22e-05	344	65	8	GO:0003018
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC6A1 SLC6A2 SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 GLRA2 AGTR1 NPSR1 SLC36A3 GRM6 KCNH5	1.42e-05	1017	65	13	GO:0098660
GeneOntologyBiologicalProcess	positive regulation of cyclase activity	DRD1 DRD5 ADRB2 ADRB3	1.57e-05	48	65	4	GO:0031281
GeneOntologyBiologicalProcess	positive regulation of lyase activity	DRD1 DRD5 ADRB2 ADRB3	1.71e-05	49	65	4	GO:0051349
GeneOntologyBiologicalProcess	positive regulation of cation transmembrane transport	SLC9A1 DRD1 ADRB2 AGTR1 NPSR1 GRM6	1.81e-05	174	65	6	GO:1904064
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transport	SLC9A1 DRD1 ADRB2 AGTR1 NPSR1 TACR2 GRM6	2.02e-05	266	65	7	GO:0043270
GeneOntologyBiologicalProcess	neurotransmitter uptake	SLC6A1 SLC6A2 DRD1 DRD2	2.17e-05	52	65	4	GO:0001504
GeneOntologyBiologicalProcess	positive regulation of cilium-dependent cell motility	OR4M2 OR4M1 TACR2	2.36e-05	18	65	3	GO:2000155
GeneOntologyBiologicalProcess	positive regulation of flagellated sperm motility	OR4M2 OR4M1 TACR2	2.36e-05	18	65	3	GO:1902093
GeneOntologyBiologicalProcess	monoatomic anion transport	SLC6A1 LRRC8E LRRC8C GPR89B GLRA2 GPR89A	2.40e-05	183	65	6	GO:0006820
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC6A1 SLC6A2 SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 AGTR1 NPSR1 SLC36A3 GRM6 KCNH5	2.68e-05	922	65	12	GO:0098662
GeneOntologyBiologicalProcess	chemical homeostasis	GPR89B OR4M2 SLC9A4 SLC9A1 DRD1 DRD2 DRD5 ABCA12 AGTR1 NPSR1 OR4M1 GPR89A ATP13A3 ADCY6	2.75e-05	1249	65	14	GO:0048878
GeneOntologyBiologicalProcess	regulation of calcium ion import across plasma membrane	ADRB2 AGTR1 GRM6	2.79e-05	19	65	3	GO:1905664
GeneOntologyBiologicalProcess	positive regulation of cilium movement	OR4M2 OR4M1 TACR2	2.79e-05	19	65	3	GO:0003353
GeneOntologyBiologicalProcess	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	ADRB2 ADRB3	2.93e-05	3	65	2	GO:0002025
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transmembrane transport	SLC9A1 DRD1 ADRB2 AGTR1 NPSR1 GRM6	3.15e-05	192	65	6	GO:0034767
GeneOntologyBiologicalProcess	dopamine uptake	SLC6A2 DRD1 DRD2	3.28e-05	20	65	3	GO:0090494
GeneOntologyBiologicalProcess	catecholamine uptake	SLC6A2 DRD1 DRD2	3.81e-05	21	65	3	GO:0090493
GeneOntologyBiologicalProcess	regulation of pH	GPR89B SLC9A4 SLC9A1 AGTR1 GPR89A	3.83e-05	120	65	5	GO:0006885
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	DRD1 ADRB3 CALCRL CHRM4	4.10e-05	61	65	4	GO:0007187
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure mediated by a chemical signal	DRD5 ADRB2 ADRB3 AGTR1	4.10e-05	61	65	4	GO:0003044
GeneOntologyBiologicalProcess	regulation of tube diameter	DRD1 DRD5 ADRB2 ADRB3 AGTR1 ADCY6	4.18e-05	202	65	6	GO:0035296
GeneOntologyBiologicalProcess	blood vessel diameter maintenance	DRD1 DRD5 ADRB2 ADRB3 AGTR1 ADCY6	4.18e-05	202	65	6	GO:0097746
GeneOntologyBiologicalProcess	regulation of tube size	DRD1 DRD5 ADRB2 ADRB3 AGTR1 ADCY6	4.30e-05	203	65	6	GO:0035150
GeneOntologyBiologicalProcess	regulation of systemic arterial blood pressure	DRD2 DRD5 ADRB2 ADRB3 AGTR1	4.48e-05	124	65	5	GO:0003073
GeneOntologyBiologicalProcess	cellular homeostasis	SLC6A2 LRRC8E GPR89B SLC9A4 SLC9A1 DRD1 DRD2 DRD5 ABCA12 NPSR1 GPR89A ATP13A3	4.90e-05	981	65	12	GO:0019725
GeneOntologyBiologicalProcess	cellular response to dopamine	DRD1 DRD2 DRD5 ADCY6	4.95e-05	64	65	4	GO:1903351
GeneOntologyBiologicalProcess	learning	SLC6A1 DRD1 DRD2 DRD5 ADRB2 TACR2	5.47e-05	212	65	6	GO:0007612
GeneOntologyBiologicalProcess	response to dopamine	DRD1 DRD2 DRD5 ADCY6	5.59e-05	66	65	4	GO:1903350
GeneOntologyBiologicalProcess	associative learning	SLC6A1 DRD1 DRD2 DRD5 ADRB2	5.62e-05	130	65	5	GO:0008306
GeneOntologyBiologicalProcess	metal ion transport	SLC6A1 SLC6A2 SLC9A4 SLC9A1 DRD1 DRD2 ADRB2 AGTR1 NPSR1 CALCRL GRM6 KCNH5	5.89e-05	1000	65	12	GO:0030001
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	DRD1 DRD2 ADRB2 AGTR1 NPSR1 GRM6	6.23e-05	217	65	6	GO:0097553
GeneOntologyBiologicalProcess	phospholipase C-activating G protein-coupled receptor signaling pathway	DRD1 DRD2 DRD5 AGTR1 GRPR	6.26e-05	133	65	5	GO:0007200
GeneOntologyBiologicalProcess	smooth muscle contraction	DRD1 DRD2 ADRB2 TACR2 CALCRL	6.26e-05	133	65	5	GO:0006939
GeneOntologyBiologicalProcess	cellular response to monoamine stimulus	DRD1 DRD2 DRD5 ADCY6	6.29e-05	68	65	4	GO:0071868
GeneOntologyBiologicalProcess	cellular response to catecholamine stimulus	DRD1 DRD2 DRD5 ADCY6	6.29e-05	68	65	4	GO:0071870
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	GPR89B SLC9A4 SLC9A1 DRD1 DRD2 DRD5 AGTR1 NPSR1 GPR89A ATP13A3	6.69e-05	705	65	10	GO:0055080
GeneOntologyBiologicalProcess	regulation of calcium ion transport	SLC9A1 DRD1 DRD2 ADRB2 AGTR1 NPSR1 GRM6	6.92e-05	323	65	7	GO:0051924
GeneOntologyBiologicalProcess	negative regulation of blood pressure	DRD2 DRD5 ADRB2 ADRB3	7.04e-05	70	65	4	GO:0045776
GeneOntologyBiologicalProcess	response to cocaine	SLC6A1 DRD1 DRD2 DRD5	7.45e-05	71	65	4	GO:0042220
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	GPR89B SLC9A4 SLC9A1 DRD1 DRD2 DRD5 AGTR1 NPSR1 GPR89A ATP13A3	7.69e-05	717	65	10	GO:0050801
GeneOntologyBiologicalProcess	sodium ion import across plasma membrane	SLC6A1 SLC9A4 SLC9A1	8.28e-05	27	65	3	GO:0098719
GeneOntologyBiologicalProcess	circulatory system process	SLC6A1 SLC9A1 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 TACR2 ADCY6	9.23e-05	733	65	10	GO:0003013
GeneOntologyBiologicalProcess	regulation of flagellated sperm motility	OR4M2 OR4M1 TACR2	9.25e-05	28	65	3	GO:1901317
GeneOntologyBiologicalProcess	behavior	SLC6A1 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 GRM6 GRPR	9.70e-05	891	65	11	GO:0007610
GeneOntologyBiologicalProcess	operant conditioning	DRD1 TACR2	9.72e-05	5	65	2	GO:0035106
GeneOntologyBiologicalProcess	sensitization	DRD1 DRD5	9.72e-05	5	65	2	GO:0046960
GeneOntologyBiologicalProcess	phasic smooth muscle contraction	DRD1 DRD2 TACR2	1.14e-04	30	65	3	GO:0014821
GeneOntologyBiologicalProcess	regulation of urine volume	DRD2 ADRB2 ADCY6	1.14e-04	30	65	3	GO:0035809
GeneOntologyBiologicalProcess	negative regulation of synaptic transmission	SLC6A1 DRD1 DRD2 DRD5	1.19e-04	80	65	4	GO:0050805
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	GPR89B SLC9A4 SLC9A1 DRD1 DRD2 DRD5 NPSR1 GPR89A ATP13A3	1.21e-04	611	65	9	GO:0030003
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	GPR89B SLC9A4 SLC9A1 DRD1 DRD2 DRD5 NPSR1 GPR89A ATP13A3	1.38e-04	622	65	9	GO:0006873
GeneOntologyBiologicalProcess	negative regulation of circadian sleep/wake cycle, sleep	DRD1 DRD2	1.45e-04	6	65	2	GO:0042321
GeneOntologyBiologicalProcess	cerebral cortex GABAergic interneuron migration	DRD1 DRD2	1.45e-04	6	65	2	GO:0021853
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	DRD2 GRM6 CHRM4 ADCY6	1.57e-04	86	65	4	GO:0007193
GeneOntologyBiologicalProcess	feeding behavior	DRD1 DRD2 ADRB3 AGTR1 NPSR1	1.59e-04	162	65	5	GO:0007631
GeneOntologyBiologicalProcess	positive regulation of calcium ion import	ADRB2 AGTR1 GRM6	1.67e-04	34	65	3	GO:0090280
GeneOntologyBiologicalProcess	learning or memory	SLC6A1 DRD1 DRD2 DRD5 ADRB2 TACR2 GRPR	1.69e-04	373	65	7	GO:0007611
GeneOntologyBiologicalProcess	blood circulation	SLC9A1 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 TACR2 ADCY6	1.87e-04	648	65	9	GO:0008015
GeneOntologyCellularComponent	G protein-coupled receptor complex	DRD1 DRD2 CALCRL	4.87e-06	11	66	3	GO:0097648
GeneOntologyCellularComponent	postsynaptic membrane	SLC6A1 DRD1 DRD2 DRD5 ADRB2 GLRA2 GRM6 CHRM4	3.99e-05	405	66	8	GO:0045211
GeneOntologyCellularComponent	synaptic membrane	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 ADRB2 GLRA2 GRM6 CHRM4	8.62e-05	583	66	9	GO:0097060
GeneOntologyCellularComponent	ciliary membrane	TAS2R4 DRD1 DRD2 DRD5	2.62e-04	98	66	4	GO:0060170
GeneOntologyCellularComponent	monoatomic ion channel complex	LRRC8E LRRC8C GPR89B GLRA2 GPR89A KCNH5	1.22e-03	378	66	6	GO:0034702
GeneOntologyCellularComponent	transmembrane transporter complex	LRRC8E LRRC8C GPR89B SLC9A1 GLRA2 GPR89A KCNH5	1.28e-03	523	66	7	GO:1902495
GeneOntologyCellularComponent	transporter complex	LRRC8E LRRC8C GPR89B SLC9A1 GLRA2 GPR89A KCNH5	1.71e-03	550	66	7	GO:1990351
GeneOntologyCellularComponent	GABA-ergic synapse	SLC6A1 DRD1 DRD2 GLRA2	1.80e-03	164	66	4	GO:0098982
GeneOntologyCellularComponent	presynaptic membrane	SLC6A1 SLC6A2 DRD1 DRD2 CHRM4	1.82e-03	277	66	5	GO:0042734
MousePheno	abnormal behavioral response to addictive substance	SLC6A1 SLC6A2 DRD1 DRD2 DRD5	7.77e-06	102	38	5	MP:0009748
MousePheno	abnormal synaptic physiology	SLC6A1 SLC6A2 SLC9A4 VRK2 DRD1 DRD2 ABCA13 GLRA2 LBR ATP9A GRM6 CHRM4	1.68e-05	1076	38	12	MP:0021009
MousePheno	decreased response to stress-induced hyperthermia	DRD1 DRD2	7.16e-05	5	38	2	MP:0010167
MousePheno	abnormal consumption behavior	SLC6A1 OR4M2 DRD2 ADRB3 ABCA12 AGTR1 OR4M1 GRPR ADCY6	7.83e-05	695	38	9	MP:0002069
MousePheno	abnormal latent inhibition of conditioning behavior	SLC6A1 DRD2	1.07e-04	6	38	2	MP:0006299
MousePheno	decreased hepatic glucose production	OR4M2 OR4M1	1.50e-04	7	38	2	MP:0020103
MousePheno	abnormal behavioral response to xenobiotic	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 CHRM4	1.69e-04	309	38	6	MP:0009745
MousePheno	increased fluid intake	SLC6A1 DRD2 AGTR1 ADCY6	1.76e-04	104	38	4	MP:0011941
MousePheno	behavioral despair	SLC6A2 VRK2 DRD1	2.27e-04	44	38	3	MP:0002573
MousePheno	impaired behavioral response to addictive substance	SLC6A2 DRD1 DRD2	2.43e-04	45	38	3	MP:0009750
MousePheno	abnormal synaptic transmission	SLC6A1 SLC6A2 SLC9A4 DRD2 ABCA13 GLRA2 LBR ATP9A GRM6 CHRM4	4.32e-04	1070	38	10	MP:0003635
MousePheno	abnormal response to stress-induced hyperthermia	DRD1 DRD2	4.67e-04	12	38	2	MP:0010165
MousePheno	abnormal fluid intake	SLC6A1 DRD2 AGTR1 ADCY6	4.89e-04	136	38	4	MP:0011947
MousePheno	abnormal operant conditioning behavior	DRD1 DRD2	5.51e-04	13	38	2	MP:0002803
Domain	G_PROTEIN_RECEP_F1_2	OR4M2 TAS2R9 DRD1 DRD2 DRD5 ADRB2 ADRB3 OR2AT4 OR4A16 OR5L1 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 OR1F2P TACR2 OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 CHRM4 GRPR OR51B2 OR8B3 OR4D2	8.90e-25	691	59	28	PS50262
Domain	GPCR_Rhodpsn	OR4M2 TAS2R9 DRD1 DRD2 DRD5 ADRB2 ADRB3 OR2AT4 OR4A16 OR5L1 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 OR1F2P TACR2 OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 CHRM4 GRPR OR51B2 OR8B3 OR4D2	9.26e-25	692	59	28	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR4M2 TAS2R9 DRD1 DRD2 DRD5 ADRB2 ADRB3 OR2AT4 OR4A16 OR5L1 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 TACR2 OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 CHRM4 GRPR OR51B2 OR8B3 OR4D2	9.36e-24	670	59	27	IPR017452
Domain	7tm_1	OR4M2 DRD1 DRD2 DRD5 ADRB2 ADRB3 OR2AT4 OR4A16 OR5L1 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 OR1F2P TACR2 OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 CHRM4 GRPR OR51B2 OR8B3 OR4D2	1.23e-23	677	59	27	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR4M2 DRD1 DRD2 DRD5 ADRB2 ADRB3 OR2AT4 OR4A16 OR5L1 AGTR1 NPSR1 OR5B17 OR2G2 OR4M1 OR1F2P TACR2 OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 CHRM4 GRPR OR51B2 OR8B3 OR4D2	1.68e-23	685	59	27	PS00237
Domain	Olfact_rcpt	OR4M2 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 OR51B2 OR8B3 OR4D2	2.73e-15	393	59	17	IPR000725
Domain	7TM_GPCR_Srsx	DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 TACR2 CHRM4 GRPR	7.08e-11	112	59	9	SM01381
Domain	Dopamine_rcpt	DRD1 DRD2 DRD5	2.98e-07	5	59	3	IPR000929
Domain	NEXCaM_BD	SLC9A4 SLC9A1	2.94e-05	3	59	2	PF16644
Domain	NHE_CaM-bd	SLC9A4 SLC9A1	2.94e-05	3	59	2	IPR032103
Domain	LMBR1	LMBRD2 LMBRD1	5.86e-05	4	59	2	PF04791
Domain	LMBR1-like_membr_prot	LMBRD2 LMBRD1	5.86e-05	4	59	2	IPR006876
Domain	LRRC8_Pannexin-like	LRRC8E LRRC8C	9.75e-05	5	59	2	IPR021040
Domain	Pannexin_like	LRRC8E LRRC8C	9.75e-05	5	59	2	PF12534
Domain	NaH_exchanger	SLC9A4 SLC9A1	3.48e-04	9	59	2	IPR004709
Domain	ADR_fam	ADRB2 ADRB3	4.34e-04	10	59	2	IPR002233
Domain	Cation/H_exchanger_CPA1	SLC9A4 SLC9A1	5.30e-04	11	59	2	IPR018422
Domain	ABC_A	ABCA12 ABCA13	6.34e-04	12	59	2	IPR026082
Domain	Na_H_Exchanger	SLC9A4 SLC9A1	8.71e-04	14	59	2	PF00999
Domain	Cation/H_exchanger	SLC9A4 SLC9A1	8.71e-04	14	59	2	IPR006153
Domain	NA_NEUROTRAN_SYMP_2	SLC6A1 SLC6A2	1.45e-03	18	59	2	PS00754
Domain	NA_NEUROTRAN_SYMP_3	SLC6A1 SLC6A2	1.62e-03	19	59	2	PS50267
Domain	SNF	SLC6A1 SLC6A2	1.62e-03	19	59	2	PF00209
Domain	Na/ntran_symport	SLC6A1 SLC6A2	1.62e-03	19	59	2	IPR000175
Domain	NA_NEUROTRAN_SYMP_1	SLC6A1 SLC6A2	1.62e-03	19	59	2	PS00610
Domain	TAS2R	TAS2R4 TAS2R9	3.04e-03	26	59	2	PF05296
Domain	T2R	TAS2R4 TAS2R9	3.04e-03	26	59	2	IPR007960
Domain	-	ATP13A3 ATP9A	4.58e-03	32	59	2	2.70.150.10
Domain	-	ATP13A3 ATP9A	4.58e-03	32	59	2	3.40.1110.10
Domain	ATPase_P-typ_cyto_domN	ATP13A3 ATP9A	5.46e-03	35	59	2	IPR023299
Domain	ATPase_P-typ_P_site	ATP13A3 ATP9A	5.77e-03	36	59	2	IPR018303
Domain	P_typ_ATPase	ATP13A3 ATP9A	5.77e-03	36	59	2	IPR001757
Domain	ATPASE_E1_E2	ATP13A3 ATP9A	5.77e-03	36	59	2	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP13A3 ATP9A	6.09e-03	37	59	2	IPR008250
Domain	E1-E2_ATPase	ATP13A3 ATP9A	6.09e-03	37	59	2	PF00122
Domain	ABC_TRANSPORTER_2	ABCA12 ABCA13	1.01e-02	48	59	2	PS50893
Domain	ABC_tran	ABCA12 ABCA13	1.01e-02	48	59	2	PF00005
Domain	ABC_TRANSPORTER_1	ABCA12 ABCA13	1.05e-02	49	59	2	PS00211
Domain	ABC_transporter-like	ABCA12 ABCA13	1.09e-02	50	59	2	IPR003439
Domain	-	ATP13A3 ATP9A	1.74e-02	64	59	2	3.40.50.1000
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 OR51B2 OR8B3 OR4D2	1.79e-13	417	55	17	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR4M2 TAS2R4 OR5AC1 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 OR51B2 OR8B3 OR4D2	1.43e-11	636	55	18	M41834
Pathway	WP_GPCRS_NONODORANT	TAS2R4 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 CALCRL GRM6 CHRM4 GRPR	2.06e-11	266	55	13	MM15843
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR4M2 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR8U3 OR2T10 OR5M8 OR8D4 OR5AR1 OR51B2 OR4D2	1.83e-10	389	55	14	M14091
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	DRD1 DRD2 DRD5 ADRB2 ADRB3 GLRA2 AGTR1 TACR2 CALCRL GRM6 CHRM4 GRPR	4.39e-10	272	55	12	M13380
Pathway	REACTOME_GPCR_LIGAND_BINDING	TAS2R4 TAS2R9 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 CALCRL GRM6 CHRM4 GRPR	1.77e-09	463	55	14	M507
Pathway	WP_MONOAMINE_GPCRS	DRD1 DRD2 DRD5 ADRB2 ADRB3 CHRM4	1.82e-09	31	55	6	MM15871
Pathway	WP_MONOAMINE_GPCRS	DRD1 DRD2 DRD5 ADRB2 ADRB3 CHRM4	2.72e-09	33	55	6	M39585
Pathway	REACTOME_GPCR_LIGAND_BINDING	TAS2R4 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 CALCRL GRM6 CHRM4 GRPR	7.47e-09	430	55	13	MM15160
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	DRD1 DRD2 DRD5 ADRB2 ADRB3 CHRM4	1.25e-08	42	55	6	M5868
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	DRD1 DRD2 DRD5 ADRB2 ADRB3 CHRM4	1.25e-08	42	55	6	MM14971
Pathway	REACTOME_SIGNALING_BY_GPCR	TAS2R4 TAS2R9 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 CALCRL GRM6 CHRM4 GRPR ADCY6	4.58e-08	702	55	15	M746
Pathway	REACTOME_SIGNALING_BY_GPCR	TAS2R4 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 CALCRL GRM6 CHRM4 GRPR ADCY6	1.19e-07	646	55	14	MM14962
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 CHRM4 GRPR	4.95e-07	330	55	10	M18334
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 NPSR1 TACR2 CHRM4 GRPR	5.38e-07	333	55	10	MM14963
Pathway	REACTOME_DOPAMINE_RECEPTORS	DRD1 DRD2 DRD5	5.59e-07	5	55	3	M27301
Pathway	REACTOME_DOPAMINE_RECEPTORS	DRD1 DRD2 DRD5	5.59e-07	5	55	3	MM15007
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	DRD1 DRD5 ADRB2 ADRB3 NPSR1 CALCRL ADCY6	2.41e-06	157	55	7	M4904
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	DRD1 DRD5 ADRB2 ADRB3 AGTR1 TACR2 GRPR	5.54e-06	178	55	7	M2890
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 CHRM4 GRPR	6.92e-06	260	55	8	M39397
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	DRD1 DRD5 ADRB2 ADRB3 NPSR1 CALCRL	1.89e-05	143	55	6	MM15055
Pathway	WP_GPCRS_OTHER	DRD1 DRD2 DRD5 ADRB2 OR1F2P	3.50e-05	96	55	5	MM15939
Pathway	WP_ADHD_AND_AUTISM_ASD_PATHWAYS	SLC6A1 SLC6A2 DRD2 DRD5 ADRB2 AGTR1 GRM6 LMBRD1	8.17e-05	367	55	8	M48346
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	ADRB2 ADRB3 AGTR1 OR13C7 CHRM4 GRPR	8.25e-05	186	55	6	MM15994
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2AT4 OR8B2 OR8B3 OR4D2	1.57e-04	70	55	4	MM14984
Pathway	WP_GPCRS_ODORANT	GPR89B GPR89A OR8B2 OR5AR1 OR8B3	3.57e-04	157	55	5	MM15872
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R4 TAS2R9 GRM6	4.65e-04	39	55	3	M793
Pathway	REACTOME_ADRENOCEPTORS	ADRB2 ADRB3	5.29e-04	9	55	2	M27302
Pathway	REACTOME_ADRENOCEPTORS	ADRB2 ADRB3	5.29e-04	9	55	2	MM15009
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A4 SLC9A1	5.29e-04	9	55	2	M27337
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A4 SLC9A1	5.29e-04	9	55	2	MM15079
Pathway	REACTOME_SENSORY_PERCEPTION	TAS2R4 OR2AT4 OR8B2 OR8B3 OR4D2	8.50e-04	190	55	5	MM15687
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY	AGTR1 TACR2 GRPR	9.67e-04	50	55	3	M47951
Pathway	KEGG_TASTE_TRANSDUCTION	TAS2R4 TAS2R9 ADCY6	1.08e-03	52	55	3	M5785
Pathway	WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION	DRD1 DRD2 ADCY6	1.28e-03	55	55	3	M39763
Pathway	BIOCARTA_CK1_PATHWAY	DRD1 DRD2	1.52e-03	15	55	2	MM1468
Pathway	KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY	ADRB2 ADCY6	1.52e-03	15	55	2	M47794
Pathway	BIOCARTA_CK1_PATHWAY	DRD1 DRD2	1.73e-03	16	55	2	M16626
Pathway	WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE	ADRB2 ADCY6	1.73e-03	16	55	2	M39849
Pathway	REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION	VRK2 LBR	1.96e-03	17	55	2	MM14920
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A1 SLC6A2 LRRC8E LRRC8C SLC9A4 SLC9A1 ABCA12 ATP9A ADCY6	2.01e-03	736	55	9	M27287
Pathway	WP_GPCRS_ORPHAN	GPR89B GPR89A	2.45e-03	19	55	2	MM15991
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A1 SLC6A2	2.45e-03	19	55	2	MM15107
Pathway	REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION	VRK2 LBR	2.45e-03	19	55	2	M29617
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A1 SLC6A2	2.45e-03	19	55	2	M27362
Pathway	WP_GPCRS_PEPTIDE	AGTR1 TACR2 GRPR	2.56e-03	70	55	3	MM15959
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	ADRB2 ADRB3 CHRM4 ADCY6	2.56e-03	147	55	4	MM15854
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	ADRB2 ADRB3 CHRM4 ADCY6	2.82e-03	151	55	4	M39329
Pathway	WP_PEPTIDE_GPCRS	AGTR1 TACR2 GRPR	3.11e-03	75	55	3	M39696
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	LRRC8E LRRC8C	4.23e-03	25	55	2	MM15172
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	LRRC8E LRRC8C	4.57e-03	26	55	2	M27424
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A1 SLC6A2 LRRC8E LRRC8C SLC9A4 SLC9A1 ABCA12 ATP9A	4.64e-03	681	55	8	MM14985
Pathway	KEGG_GAP_JUNCTION	DRD1 DRD2 ADCY6	5.20e-03	90	55	3	M4013
Pathway	WP_MONOAMINE_TRANSPORT	SLC6A1 SLC6A2	6.88e-03	32	55	2	M39724
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	AGTR1 NPSR1 TACR2 GRPR	7.24e-03	197	55	4	M12289
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	AGTR1 NPSR1 TACR2 GRPR	7.24e-03	197	55	4	MM14970
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR4M1 OR1F2P OR8U3 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR8B3 OR4D2	2.69e-18	340	66	16	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR4M1 OR1F2P OR8U3 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR8B3 OR4D2	2.69e-18	340	66	16	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR4M1 OR1F2P OR8U3 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR8B3 OR4D2	3.09e-18	343	66	16	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR4M1 OR1F2P OR8U3 OR5M8 OR13C7 OR8B2 OR8D4 OR5AR1 OR51B2 OR8B3 OR4D2	3.55e-18	346	66	16	14611657
Pubmed	The human olfactory receptor gene family.	OR4M2 OR5AC1 OR2AT4 OR4A16 OR5L1 OR5B17 OR2G2 OR4M1 OR1F2P OR8U3 OR2T10 OR5M8 OR8B2 OR8D4 OR5AR1 OR8B3 OR4D2	1.77e-16	541	66	17	14983052
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 CALCRL CHRM4 GRPR	1.60e-10	200	66	9	18240029
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 ADRB2 GLRA2 AGTR1 TACR2 GRM6	2.70e-10	300	66	10	19086053
Pubmed	Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.	DRD1 DRD5 ADRB2 ADRB3 NPSR1 CALCRL	4.41e-09	70	66	6	12036966
Pubmed	Genetical genomic determinants of alcohol consumption in rats and humans.	SLC6A2 DRD1 DRD2 DRD5 ADRB2 GLRA2 CHRM4	5.61e-09	130	66	7	19874574
Pubmed	Calcium signaling by dopamine D5 receptor and D5-D2 receptor hetero-oligomers occurs by a mechanism distinct from that for dopamine D1-D2 receptor hetero-oligomers.	DRD1 DRD2 DRD5	6.53e-09	3	66	3	19171671
Pubmed	Differential D1 and D5 receptor regulation and degradation of the angiotensin type 1 receptor.	DRD1 DRD5 AGTR1	6.53e-09	3	66	3	18172057
Pubmed	Aging-related dysregulation of dopamine and angiotensin receptor interaction.	DRD1 DRD2 AGTR1	6.53e-09	3	66	3	24529758
Pubmed	Receptor subtypes involved in the presynaptic and postsynaptic actions of dopamine on striatal interneurons.	DRD1 DRD2 DRD5	6.53e-09	3	66	3	12867509
Pubmed	Personal receptor repertoires: olfaction as a model.	OR5L1 OR8U3 OR13C7 OR5AR1 OR51B2	1.01e-08	38	66	5	22908908
Pubmed	Low affinity binding of the classical D1 antagonist SCH23390 in rodent brain: potential interaction with A2A and D2-like receptors.	DRD1 DRD2 DRD5	2.61e-08	4	66	3	16962565
Pubmed	Association study between the phenotype migraine without aura-panic disorder and dopaminergic receptor genes.	DRD1 DRD2 DRD5	2.61e-08	4	66	3	12967601
Pubmed	Aging-related dysregulation in enteric dopamine and angiotensin system interactions: implications for gastrointestinal dysfunction in the elderly.	DRD1 DRD2 AGTR1	2.61e-08	4	66	3	29541380
Pubmed	Dopamine genes and pathological gambling in discordant sib-pairs.	DRD1 DRD2 DRD5	2.61e-08	4	66	3	17394052
Pubmed	Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells.	DRD1 DRD5 ADCY6	2.61e-08	4	66	3	25049074
Pubmed	Functional reconstitution of G-protein-coupled receptor-mediated adenylyl cyclase activation by a baculoviral co-display system.	DRD1 DRD5 ADCY6	2.61e-08	4	66	3	18403039
Pubmed	Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors.	DRD1 DRD2 DRD5 ADRB2 ADRB3	5.12e-08	52	66	5	8288218
Pubmed	Dopamine receptors: from structure to function.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	9457173
Pubmed	[Dopamine receptor signaling regulates human osteoclastogenesis].	DRD1 DRD2 DRD5	6.51e-08	5	66	3	23445730
Pubmed	Evidence against dopamine D1/D2 receptor heteromers.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	25560761
Pubmed	Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	22219295
Pubmed	Redundant catecholamine signaling consolidates fear memory via phospholipase C.	DRD1 DRD5 ADRB2	6.51e-08	5	66	3	22323706
Pubmed	The effects of spiritual intervention and changes in dopamine receptor gene expression in breast cancer patients.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	26597879
Pubmed	Impact of the dopamine receptor gene family on temperament traits in a population-based birth cohort.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	19105202
Pubmed	Neuron-specific age-related decreases in dopamine receptor subtype mRNAs.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	12509874
Pubmed	Dopamine receptor loss of function is not protective of rd1 rod photoreceptors in vivo.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	20038975
Pubmed	Systematic analysis of dopamine receptor genes (DRD1-DRD5) in antipsychotic-induced weight gain.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	20714340
Pubmed	Upregulation of renal D5 dopamine receptor ameliorates the hypertension in D3 dopamine receptor-deficient mice.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	23753418
Pubmed	Dopamine receptor mRNA and protein expression in the mouse corpus striatum and cerebral cortex during pre- and postnatal development.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	17509542
Pubmed	Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice.	DRD1 DRD2 DRD5	6.51e-08	5	66	3	18083900
Pubmed	A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP).	ADRB2 AGTR1 TACR2 CHRM4	6.91e-08	21	66	4	15452121
Pubmed	Rod vision is controlled by dopamine-dependent sensitization of rod bipolar cells by GABA.	DRD1 DRD2 DRD5	1.30e-07	6	66	3	21982372
Pubmed	DISC1 regulates primary cilia that display specific dopamine receptors.	DRD1 DRD2 DRD5	1.30e-07	6	66	3	20531939
Pubmed	A common variant in DRD3 receptor is associated with autism spectrum disorder.	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 ABCA13	1.67e-07	128	66	6	19058789
Pubmed	Two-stage case-control association study of dopamine-related genes and migraine.	DRD1 DRD2 DRD5	5.44e-07	9	66	3	19772578
Pubmed	Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice.	DRD1 DRD2 DRD5	5.44e-07	9	66	3	16525059
Pubmed	G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase.	DRD2 ADRB2 ADCY6	5.44e-07	9	66	3	12297500
Pubmed	SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families.	SLC6A2 DRD1 DRD2	5.44e-07	9	66	3	18821566
Pubmed	Confirmation of quantitative trait loci for cocaine-induced activation in the AcB/BcA series of recombinant congenic strains.	DRD1 DRD2 DRD5	5.44e-07	9	66	3	12777963
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR5L1 OR8U3 OR5AR1 OR51B2	5.92e-07	35	66	4	16939646
Pubmed	Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).	DRD1 DRD2 DRD5	7.76e-07	10	66	3	21083670
Pubmed	Support for association between ADHD and two candidate genes: NET1 and DRD1.	SLC6A2 DRD1 DRD5	1.07e-06	11	66	3	15717291
Pubmed	Genetic factors are relevant and independent determinants of antihypertensive drug effects in a multiracial population.	ADRB2 ADRB3 AGTR1	1.07e-06	11	66	3	19779464
Pubmed	Association study of 182 candidate genes in anorexia nervosa.	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	1.32e-06	182	66	6	20468064
Pubmed	Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.	SLC6A1 SLC6A2 DRD2 ADRB2	1.98e-06	47	66	4	18821565
Pubmed	Poor replication of candidate genes for major depressive disorder using genome-wide association data.	SLC6A2 DRD1 DRD2 AGTR1	2.76e-06	51	66	4	20351714
Pubmed	Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control.	DRD1 DRD2 DRD5	2.92e-06	15	66	3	26053317
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	DRD1 DRD2 DRD5 GRM6 CHRM4	3.13e-06	118	66	5	19156168
Pubmed	Lack of dopaminergic inputs elongates the primary cilia of striatal neurons.	DRD1 DRD2	3.55e-06	2	66	2	24830745
Pubmed	Differential roles of dopamine D1 and D2 receptor-containing neurons of the nucleus accumbens shell in behavioral sensitization.	DRD1 DRD2	3.55e-06	2	66	2	26442961
Pubmed	Dopamine D1 receptor, but not dopamine D2 receptor, is a critical regulator for acute cocaine-enhanced gene expression.	DRD1 DRD2	3.55e-06	2	66	2	19228458
Pubmed	Dopamine receptor D2, but not D1, mediates the reward circuit from the ventral tegmental area to the central amygdala, which is involved in pain relief.	DRD1 DRD2	3.55e-06	2	66	2	36464669
Pubmed	Early maternal separation accelerates the progression of endometriosis in adult mice.	DRD2 ADRB2	3.55e-06	2	66	2	32532293
Pubmed	Polymorphisms in dopaminergic genes predict proactive processes of response inhibition.	DRD1 DRD2	3.55e-06	2	66	2	30586202
Pubmed	Endogenous opioids mediate basal hedonic tone independent of dopamine D-1 or D-2 receptor activation.	DRD1 DRD2	3.55e-06	2	66	2	14960355
Pubmed	Lesions of mouse striatum induced by 6-hydroxydopamine differentially alter the density, rate of synthesis, and level of gene expression of D1 and D2 dopamine receptors.	DRD1 DRD2	3.55e-06	2	66	2	8294904
Pubmed	The expression of neuropeptide-induced excessive grooming behavior in dopamine D1 and D2 receptor-deficient mice.	DRD1 DRD2	3.55e-06	2	66	2	9988094
Pubmed	The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner.	DRD1 DRD5	3.55e-06	2	66	2	21893192
Pubmed	Aberrant Dopamine Receptor Signaling Plays Critical Role in the Impairment of Striatal Neurons in Experimental Cerebral Malaria.	DRD1 DRD2	3.55e-06	2	66	2	32833186
Pubmed	Activation of D1/5 Dopamine Receptors: A Common Mechanism for Enhancing Extinction of Fear and Reward-Seeking Behaviors.	DRD1 DRD5	3.55e-06	2	66	2	26763483
Pubmed	Influence of ADRB2 Gln27Glu and ADRB3 Trp64Arg polymorphisms on body weight and body composition changes after a controlled weight-loss intervention.	ADRB2 ADRB3	3.55e-06	2	66	2	26888112
Pubmed	Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA.	DRD1 DRD2	3.55e-06	2	66	2	21303698
Pubmed	Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system.	DRD1 DRD2	3.55e-06	2	66	2	11567069
Pubmed	Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice.	DRD1 DRD2	3.55e-06	2	66	2	12417685
Pubmed	When chocolate seeking becomes compulsion: gene-environment interplay.	DRD1 DRD2	3.55e-06	2	66	2	25781028
Pubmed	Genetic factors and clinical significance of acanthosis nigricans in obese Japanese children and adolescents.	ADRB2 ADRB3	3.55e-06	2	66	2	16449022
Pubmed	Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice.	DRD1 DRD2	3.55e-06	2	66	2	8001143
Pubmed	Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating.	DRD1 DRD2	3.55e-06	2	66	2	17324452
Pubmed	HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance-dependent and substance-independent populations.	DRD1 DRD2	3.55e-06	2	66	2	24078558
Pubmed	Contrasting changes in DRD1 and DRD2 splice variant expression in schizophrenia and affective disorders, and associations with SNPs in postmortem brain.	DRD1 DRD2	3.55e-06	2	66	2	24322206
Pubmed	Genetic variants of dopamine D2 receptor impact heterodimerization with dopamine D1 receptor.	DRD1 DRD2	3.55e-06	2	66	2	28119185
Pubmed	Role of dopamine receptors subtypes, D1-like and D2-like, within the nucleus accumbens subregions, core and shell, on memory consolidation in the one-trial inhibitory avoidance task.	DRD1 DRD2	3.55e-06	2	66	2	19117916
Pubmed	Differentiation of forebrain and hippocampal dopamine 1-class receptors, D1R and D5R, in spatial learning and memory.	DRD1 DRD5	3.55e-06	2	66	2	26174222
Pubmed	Two amino acids in each of D1 and D2 dopamine receptor cytoplasmic regions are involved in D1-D2 heteromer formation.	DRD1 DRD2	3.55e-06	2	66	2	22100647
Pubmed	Association of polymorphisms in the beta-2 and beta-3 adrenoceptor genes with risk of colorectal cancer in Japanese.	ADRB2 ADRB3	3.55e-06	2	66	2	11706779
Pubmed	[Polymorphisms in the beta2 and beta3 adrenergic receptor genes in obstructive sleep apnea/hypopnea syndrome].	ADRB2 ADRB3	3.55e-06	2	66	2	16009000
Pubmed	Fluorescence studies reveal heterodimerization of dopamine D1 and D2 receptors in the plasma membrane.	DRD1 DRD2	3.55e-06	2	66	2	16846218
Pubmed	Role of silent polymorphisms within the dopamine D1 receptor associated with schizophrenia on D1-D2 receptor hetero-dimerization.	DRD1 DRD2	3.55e-06	2	66	2	20081237
Pubmed	Distinct functions of the two isoforms of dopamine D2 receptors.	DRD1 DRD2	3.55e-06	2	66	2	11089973
Pubmed	Interactions among the beta2- and beta3- adrenergic receptor genes and total body fat and abdominal fat level in the HERITAGE Family Study.	ADRB2 ADRB3	3.55e-06	2	66	2	12629568
Pubmed	Selective Vulnerability of Striatal D2 versus D1 Dopamine Receptor-Expressing Medium Spiny Neurons in HIV-1 Tat Transgenic Male Mice.	DRD1 DRD2	3.55e-06	2	66	2	28473642
Pubmed	Striatal Distribution and Cytoarchitecture of Dopamine Receptor Subtype 1 and 2: Evidence from Double-Labeling Transgenic Mice.	DRD1 DRD2	3.55e-06	2	66	2	28860974
Pubmed	Dopamine receptor activation modulates GABA neuron migration from the basal forebrain to the cerebral cortex.	DRD1 DRD2	3.55e-06	2	66	2	17409246
Pubmed	PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation.	DRD1 DRD5	3.55e-06	2	66	2	26807952
Pubmed	beta-Blockade and increased dyslipidemia in patients bearing Glu27 variant of beta2 adrenergic receptor gene.	ADRB2 ADRB3	3.55e-06	2	66	2	16027735
Pubmed	beta2- and beta3-, but not beta1-adrenergic receptors are involved in osteogenesis of mouse mesenchymal stem cells via cAMP/PKA signaling.	ADRB2 ADRB3	3.55e-06	2	66	2	20138019
Pubmed	Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice.	DRD1 DRD2	3.55e-06	2	66	2	18363855
Pubmed	Whole-Brain Mapping of Direct Inputs to Dopamine D1 and D2 Receptor-Expressing Medium Spiny Neurons in the Posterior Dorsomedial Striatum.	DRD1 DRD2	3.55e-06	2	66	2	33380525
Pubmed	An analysis of the link between polymorphisms of the beta2 and beta3 adrenergic receptor gene and metabolic parameters among Polish Caucasians with familial obesity.	ADRB2 ADRB3	3.55e-06	2	66	2	12824951
Pubmed	D1 and D2 dopamine receptor-mediated inhibition of activated normal T cell proliferation is lost in jurkat T leukemic cells.	DRD1 DRD2	3.55e-06	2	66	2	20592018
Pubmed	Differential behavioral phenotypes of dopamine D1 receptor knockdown mice at the embryonic, postnatal, and adult stages.	DRD1 DRD2	3.55e-06	2	66	2	29183706
Pubmed	Accumbal dopamine D2 receptors are important for sensorimotor gating in C3H mice.	DRD1 DRD2	3.55e-06	2	66	2	17712281
Pubmed	Season of birth and dopamine receptor gene associations with impulsivity, sensation seeking and reproductive behaviors.	DRD1 DRD2	3.55e-06	2	66	2	18030347
Pubmed	D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms.	DRD1 DRD2	3.55e-06	2	66	2	23680635
Pubmed	Dissociable electrophysiological subprocesses during response inhibition are differentially modulated by dopamine D1 and D2 receptors.	DRD1 DRD2	3.55e-06	2	66	2	27021648
Pubmed	Localization of peripheral dopamine D1 and D2 receptors in rat and human seminal vesicles.	DRD1 DRD2	3.55e-06	2	66	2	11783439
Interaction	CCR6 interactions	SLC9A1 YIF1B GPR89A ATP13A3 LMBRD2 ATP9A	8.50e-08	89	50	6	int:CCR6
Interaction	FPR2 interactions	LRRC8E LRRC8C GPR89A ATP13A3 LMBRD2 ATP9A	1.15e-06	138	50	6	int:FPR2
Interaction	TSPAN15 interactions	LRRC8E LRRC8C AGTR1 GPR89A ATP13A3 ATP9A ADCY6	5.06e-06	276	50	7	int:TSPAN15
Interaction	YIPF3 interactions	DRD2 GPR89A ATP13A3 ATP9A CHRM4 ADCY6	6.47e-06	186	50	6	int:YIPF3
Interaction	DNAJC14 interactions	VRK2 DRD1 ADRB2 AGTR1	7.10e-06	50	50	4	int:DNAJC14
Interaction	TTYH1 interactions	LRRC8E LRRC8C SLC9A1 DRD2 GPR89A LMBRD2 ADCY6	8.72e-06	300	50	7	int:TTYH1
Interaction	LPAR1 interactions	LRRC8E SLC9A1 DRD2 GPR89A ATP9A ADCY6	1.29e-05	210	50	6	int:LPAR1
Interaction	LRRC55 interactions	LRRC8E PIGB SLC9A1 ATP9A	2.16e-05	66	50	4	int:LRRC55
Interaction	GPRASP1 interactions	ADRB2 AGTR1 TACR2 CHRM4	2.29e-05	67	50	4	int:GPRASP1
Interaction	OR10H2 interactions	LRRC8E LRRC8C ATP13A3 ADCY6	3.05e-05	72	50	4	int:OR10H2
Interaction	SLC39A4 interactions	ADRB2 GPR89A ATP13A3 ATP9A ADCY6	5.14e-05	163	50	5	int:SLC39A4
Interaction	HRH3 interactions	DRD1 DRD2	6.00e-05	5	50	2	int:HRH3
Interaction	TMEM101 interactions	DRD2 TMEM243 NPSR1	6.15e-05	31	50	3	int:TMEM101
Interaction	TSPAN7 interactions	DRD2 ADRB2 CHRM4	6.77e-05	32	50	3	int:TSPAN7
Interaction	LGALS8 interactions	LRRC8E LRRC8C ATP13A3 ADCY6 SLC35A5	7.01e-05	174	50	5	int:LGALS8
Interaction	ADRB3 interactions	ADRB2 ADRB3	8.99e-05	6	50	2	int:ADRB3
Interaction	C3orf52 interactions	LRRC8E PIGB VRK2 SLC9A1 ATP13A3 ADCY6	1.04e-04	305	50	6	int:C3orf52
Interaction	SMIM7 interactions	DRD2 CHRM4	1.26e-04	7	50	2	int:SMIM7
Interaction	NIPAL1 interactions	GPR89A ATP13A3 LMBRD2 ATP9A	1.83e-04	114	50	4	int:NIPAL1
Interaction	IPPK interactions	SLC9A1 GPR89A ATP9A ADCY6	1.96e-04	116	50	4	int:IPPK
Interaction	CYP19A1 interactions	LRRC8E VRK2 ATP13A3	2.02e-04	46	50	3	int:CYP19A1
Interaction	KCNJ9 interactions	DRD2 ADRB2	2.15e-04	9	50	2	int:KCNJ9
Interaction	KCNA2 interactions	LRRC8E LRRC8C VRK2 ATP9A	2.61e-04	125	50	4	int:KCNA2
Interaction	PTGER1 interactions	DRD1 ADRB2	2.68e-04	10	50	2	int:PTGER1
Interaction	ICAM2 interactions	LRRC8E YIF1B CMTM8	4.03e-04	58	50	3	int:ICAM2
Interaction	GRPR interactions	GPR89A LMBRD2 GRPR	4.67e-04	61	50	3	int:GRPR
Interaction	CHP2 interactions	SLC9A4 SLC9A1	5.39e-04	14	50	2	int:CHP2
Interaction	JKAMP interactions	ADRB2 AGTR1	5.39e-04	14	50	2	int:JKAMP
Interaction	NKAIN1 interactions	LRRC8E GPR89A ADCY6	5.63e-04	65	50	3	int:NKAIN1
Interaction	CRELD1 interactions	DRD2 GPR89A LMBRD2 ATP9A	7.11e-04	163	50	4	int:CRELD1
Interaction	CHRNB4 interactions	PIGB GPR89A ATP13A3	7.60e-04	72	50	3	int:CHRNB4
Interaction	GPR182 interactions	LRRC8E VRK2 YIF1B GPR89A ATP13A3 LMBRD2	8.78e-04	455	50	6	int:GPR182
Interaction	TACR3 interactions	VRK2 GPR89A LMBRD2	8.89e-04	76	50	3	int:TACR3
Interaction	RAB4A interactions	VRK2 AGTR1 LARS1 ATP13A3 ATP9A GRPR	8.98e-04	457	50	6	int:RAB4A
Interaction	KCNJ3 interactions	DRD2 ADRB2	9.00e-04	18	50	2	int:KCNJ3
Interaction	STRA6 interactions	SLC9A1 GPR89A	9.00e-04	18	50	2	int:STRA6
Interaction	TCTN2 interactions	PIGB VRK2 SLC9A1 GPR89A LBR	9.19e-04	304	50	5	int:TCTN2
Interaction	SLC1A1 interactions	VRK2 YIF1B GPR89A CMTM8	9.67e-04	177	50	4	int:SLC1A1
Interaction	ADCK1 interactions	CHRM4 GRPR CMTM8	9.95e-04	79	50	3	int:ADCK1
Interaction	RAB3B interactions	VRK2 LBR ATP9A CHRM4 GRPR	1.00e-03	310	50	5	int:RAB3B
Interaction	SERINC3 interactions	DRD2 AGTR1	1.00e-03	19	50	2	int:SERINC3
Interaction	GPR37 interactions	DRD2 ADRB2 YIF1B	1.07e-03	81	50	3	int:GPR37
Interaction	MBOAT7 interactions	LBR LMBRD1 SLC35A5 CMTM8	1.07e-03	182	50	4	int:MBOAT7
Cytoband	11q12.1	OR5B17 OR8U3 OR5M8 OR5AR1	8.35e-05	161	65	4	11q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR5L1 OR5B17 OR8U3 OR5M8 OR5AR1	1.33e-04	345	65	5	chr11q12
Cytoband	11q24.1	OR8B2 OR8D4	1.27e-03	37	65	2	11q24.1
Cytoband	Xp22.2	GLRA2 GRPR	1.49e-03	40	65	2	Xp22.2
Cytoband	11q11	OR4A16 OR5L1	2.05e-03	47	65	2	11q11
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	OR8B2 OR8D4 OR8B3	2.56e-03	191	65	3	chr11q24
Cytoband	1q21.1	GPR89B GPR89A	3.53e-03	62	65	2	1q21.1
GeneFamily	Dopamine receptors	DRD1 DRD2 DRD5	2.80e-07	5	56	3	181
GeneFamily	Olfactory receptors, family 5	OR5AC1 OR5L1 OR5B17 OR8U3 OR5M8 OR5AR1	1.25e-06	112	56	6	152
GeneFamily	Volume regulated anion channel subunits	LRRC8E LRRC8C	9.37e-05	5	56	2	1158
GeneFamily	Taste 2 receptors	TAS2R4 TAS2R9 TAS2R33	2.38e-04	39	56	3	1162
GeneFamily	Adrenoceptors	ADRB2 ADRB3	3.35e-04	9	56	2	169
GeneFamily	Olfactory receptors, family 8	OR8B2 OR8D4 OR8B3	4.69e-04	49	56	3	155
GeneFamily	Olfactory receptors, family 4	OR4M2 OR4A16 OR4M1 OR4D2	6.82e-04	129	56	4	151
GeneFamily	ATP binding cassette subfamily A	ABCA12 ABCA13	8.37e-04	14	56	2	805
GeneFamily	Solute carriers	SLC6A1 SLC6A2 SLC9A4 SLC9A1 SLC36A3 SLC35A5	1.35e-03	395	56	6	752
GeneFamily	Olfactory receptors, family 2	OR2AT4 OR2G2 OR2T10	5.18e-03	113	56	3	149
Coexpression	YOSHIMURA_MAPK8_TARGETS_UP	SLC6A2 DRD1 DRD2 ADRB2 ADRB3 OR2AT4 AGTR1 TACR2 CALCRL ATP9A OR13C7 GRPR KCNH5	4.23e-06	1281	59	13	M1884
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Crh\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DRD1 DRD5 OR2AT4 GLRA2 TMEM243	1.55e-06	136	64	5	44f03e4f55fb2c5f8b9397142c89f7194b009cc6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Whrn_Tox2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VRK2 SPTSSB TMEM243 NPSR1 KCNH5	1.98e-06	143	64	5	36ce6f163fb33141c86288086c354b91853fad25
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DRD1 DRD5 ABCA12 SPTSSB GLRA2	2.43e-06	149	64	5	558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC6A1 SLC6A2 GLRA2 GRPR CMTM8	7.54e-06	188	64	5	c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
Computational	Genes in the cancer module 288.	AGTR1 TACR2 GRPR	1.04e-04	37	27	3	MODULE_288
Computational	Genes in the cancer module 146.	ADRB2 AGTR1 CALCRL GRPR	1.13e-04	102	27	4	MODULE_146
Computational	Membranal receptors.	SLC6A1 SLC6A2 ADRB2 GLRA2 AGTR1 CALCRL GRPR	2.19e-04	517	27	7	MODULE_64
Computational	Genes in the cancer module 162.	SLC6A1 SLC6A2	1.01e-03	19	27	2	MODULE_162
Computational	Vesicular transport / synapse genes.	SLC6A2 DRD2 GLRA2	1.10e-03	82	27	3	MODULE_274
Computational	Genes in the cancer module 218.	SLC6A1 SLC6A2	1.12e-03	20	27	2	MODULE_218
Drug	DO 710	DRD1 DRD2 DRD5 ADRB2 ADRB3	2.91e-11	10	61	5	CID003084985
Drug	3-isoreserpine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3 ABCA12 ABCA13 ADCY6 KCNH5	8.05e-11	190	61	10	CID000005052
Drug	Bulbokaprin	DRD1 DRD2 DRD5 ADRB2 ADRB3	1.48e-10	13	61	5	CID000009276
Drug	AC1Q5UBL	SLC6A1 SLC6A2 SLC9A1 DRD1 DRD2 DRD5 ADRB2 ADRB3 GRM6	1.87e-10	146	61	9	CID000005466
Drug	benzimidazol-2-one	DRD1 DRD2 DRD5 ADRB2 ADRB3	2.29e-10	14	61	5	CID000162542
Drug	dopexamine	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	2.47e-10	32	61	6	CID000055483
Drug	delta H	DRD1 DRD2 DRD5 ADRB2 ADRB3	4.99e-10	16	61	5	CID000034771
Drug	N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	6.58e-10	69	61	7	CID000003172
Drug	fenoldopam	DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 ADCY6	7.30e-10	70	61	7	CID000003340
Drug	NSC95090	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	1.03e-09	40	61	6	CID000003251
Drug	DAR-0100A	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADCY6	1.20e-09	41	61	6	CID000060759
Drug	nisoxetine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	1.40e-09	42	61	6	CID000004500
Drug	phentolamine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 TACR2 ADCY6	3.04e-09	200	61	9	CID000005775
Drug	Neomigran	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	3.23e-09	48	61	6	CID000003066
Drug	1-methyl-3,4-dihydroisoquinoline	SLC6A2 DRD1 DRD2 DRD5	3.24e-09	8	61	4	CID000231502
Drug	mianserin	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	3.43e-09	87	61	7	CID000004184
Drug	dihydroergocryptine	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	3.67e-09	49	61	6	CID000114948
Drug	amitriptyline	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3 LARS1	3.74e-09	140	61	8	CID000002160
Drug	5,6-dihydroxy-2-dimethylaminotetralin	DRD1 DRD2 DRD5 ADRB2 ADRB3	4.77e-09	24	61	5	CID000037032
Drug	ibopamine	DRD1 DRD2 DRD5 ADRB2 ADRB3	4.77e-09	24	61	5	CID000068555
Drug	epinine	DRD1 DRD2 DRD5 ADRB2 ADRB3	4.77e-09	24	61	5	CID000004382
Drug	mirtazapine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	6.71e-09	54	61	6	CID000004205
Drug	tardan	DRD1 DRD2 DRD5 ADRB2 ADRB3	7.36e-09	26	61	5	CID000002729
Drug	piperoxan	DRD1 DRD2 DRD5 ADRB2 ADRB3	7.36e-09	26	61	5	CID000006040
Drug	MHPG	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	9.38e-09	57	61	6	CID000010805
Drug	AC1L1CM5	DRD1 DRD2 DRD5 ADRB2	1.52e-08	11	61	4	CID000001961
Drug	AC1LR3WA	DRD1 DRD2 DRD5	1.83e-08	3	61	3	CID001361946
Drug	carphenazine	DRD1 DRD2 DRD5	1.83e-08	3	61	3	CID000018104
Drug	Carphenazine	DRD1 DRD2 DRD5	1.83e-08	3	61	3	DB01038
Drug	S-(-)-Lisuride	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	2.10e-08	65	61	6	CID000003938
Drug	talsupram	SLC6A2 DRD1 DRD2 DRD5	2.27e-08	12	61	4	CID000033013
Drug	alpha-methyl-p-tyrosine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	2.30e-08	66	61	6	CID000003125
Drug	reboxetine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	2.53e-08	67	61	6	CID000065856
Drug	NSC186061	DRD1 DRD2 DRD5 ADRB2 ADRB3 TACR2 ADCY6	2.90e-08	118	61	7	CID000004163
Drug	desipramine	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	3.77e-08	188	61	8	CID000002995
Drug	EEDQ	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	3.91e-08	72	61	6	CID000027833
Drug	azaperone	DRD1 DRD2 DRD5 LBR	4.57e-08	14	61	4	CID000015443
Drug	A68930	DRD1 DRD2 DRD5 ADRB2	4.57e-08	14	61	4	CID000122324
Drug	Rp-cAMPS	DRD1 DRD2 DRD5 ADRB2 ADRB3 CALCRL GRM6 ADCY6	4.81e-08	194	61	8	CID006426631
Drug	clorgyline	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	5.01e-08	75	61	6	CID000004380
Drug	EN-1530	DRD1 DRD2 DRD5 ADRB2 ADRB3 TACR2 LBR GRM6 ADCY6	5.28e-08	278	61	9	CID000004425
Drug	tyramine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	5.68e-08	130	61	7	CID000005610
Drug	methiothepin	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	5.88e-08	77	61	6	CID000004106
Drug	H-8105	SLC6A2 SLC9A1 DRD1 DRD2 DRD5 ADRB2 YIF1B ADRB3 ADCY6	5.96e-08	282	61	9	CID000164531
Drug	SKF 75670	DRD1 DRD2 DRD5 ADCY6	6.22e-08	15	61	4	CID000173870
Drug	A 86929	DRD1 DRD2 DRD5 ADRB2	6.22e-08	15	61	4	ctd:C095427
Drug	HV723	DRD1 DRD5 ADRB2 ADRB3	6.22e-08	15	61	4	CID003081094
Drug	AC1L2AAS	DRD1 DRD2 DRD5 ADCY6	6.22e-08	15	61	4	CID000068714
Drug	amphetamine	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3 GLRA2 GRM6 ADCY6	6.33e-08	284	61	9	CID000003007
Drug	dimethocaine	DRD1 DRD2 DRD5	7.31e-08	4	61	3	CID000007177
Drug	MK-458	DRD1 DRD2 DRD5	7.31e-08	4	61	3	CID000057532
Drug	DK-118	DRD1 DRD2 DRD5	7.31e-08	4	61	3	CID000145953
Drug	buspirone	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	7.40e-08	80	61	6	CID000002477
Drug	spiroxatrine	DRD1 DRD2 DRD5 ADRB2 ADRB3	9.20e-08	42	61	5	CID000005268
Drug	NSD-1015	DRD1 DRD2 DRD5 ADRB2 ADRB3	1.04e-07	43	61	5	CID000001663
Drug	mecoprop	SLC6A2 DRD1 DRD2 ADRB2 ADRB3	1.17e-07	44	61	5	CID000007153
Drug	pilocarpine-	SLC6A1 DRD1 DRD2 DRD5 ADRB2 ADRB3 GRM6	1.32e-07	147	61	7	CID000004819
Drug	AMPT	DRD1 DRD2 DRD5 ADRB2	1.39e-07	18	61	4	CID000002112
Drug	idazoxan	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ADRB3	1.41e-07	89	61	6	CID000054459
Drug	amoxapine	SLC6A1 SLC6A2 DRD1 DRD2 DRD5	1.47e-07	46	61	5	CID000002170
Drug	B-HT 920	DRD1 DRD2 DRD5 ADRB2 ADRB3	1.64e-07	47	61	5	CID000005374
Drug	Ro 41-9067	DRD1 DRD2 DRD5 ADCY6	1.75e-07	19	61	4	CID000125800
Drug	Methotrimeprazine	DRD1 DRD2 DRD5 CHRM4	1.75e-07	19	61	4	DB01403
Drug	tilozepine	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000172286
Drug	2-di-n-propylaminoindan	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000130402
Drug	mezilamine	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000068678
Drug	C9H11N3O2	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000123703
Drug	SKF 77434	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000001241
Drug	proterguride	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000071999
Drug	NO 756	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000129967
Drug	Levodopa	DRD1 DRD2 DRD5	1.82e-07	5	61	3	DB01235
Drug	SKF85174	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000132435
Drug	l-CSL	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID006918538
Drug	sibenadet	DRD2 ADRB2 ADRB3	1.82e-07	5	61	3	CID000183811
Drug	3-iodobenzamide	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000202425
Drug	dazopride	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000054801
Drug	azapride	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID003036441
Drug	piquindone	DRD1 DRD2 DRD5	1.82e-07	5	61	3	CID000121903
Drug	zotepine	SLC6A2 DRD1 DRD2 DRD5 ADRB2	2.03e-07	49	61	5	CID000005736
Drug	sulpiride	DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	2.21e-07	96	61	6	CID000005355
Drug	clonidine	SLC6A2 SLC9A1 DRD1 DRD2 DRD5 ADRB2 ADRB3 ADCY6	2.47e-07	240	61	8	CID000002803
Drug	DAS-431	DRD1 DRD2 DRD5 ADRB2	2.70e-07	21	61	4	CID000166543
Drug	ziprasidone	SLC6A2 DRD1 DRD2 DRD5 KCNH5	3.04e-07	53	61	5	CID000060853
Drug	AC1Q5S71	DRD1 DRD2 DRD5 ADRB2 ADRB3 AGTR1 ADCY6	3.55e-07	170	61	7	CID000000501
Drug	2'-ISP	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000128389
Drug	Rotigotine	DRD1 DRD2 DRD5	3.64e-07	6	61	3	DB05271
Drug	pyrazole-3	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000354929
Drug	Zuclopenthixol	DRD1 DRD2 DRD5	3.64e-07	6	61	3	DB01624
Drug	pergolide sulfone	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000155750
Drug	pergolide sulfoxide	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000155749
Drug	A66359	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000173657
Drug	CI-943	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000146009
Drug	AC1L1JFX	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000005023
Drug	propylbutyldopamine	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000156067
Drug	N,N-dimethyldopamine	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000152427
Drug	oxiperomide	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000068634
Drug	AC1L1I8U	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000055036
Drug	LON-954	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID006441097
Drug	p-bromospiperone	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000156386
Drug	MDO-NPA	DRD1 DRD2 DRD5	3.64e-07	6	61	3	CID000133642
Disease	hypertension (is_implicated_in)	SLC6A2 DRD1 DRD2 ADRB2 ADRB3 AGTR1	1.43e-07	121	58	6	DOID:10763 (is_implicated_in)
Disease	Recurrent depression	SLC6A2 DRD1 DRD2	6.00e-07	9	58	3	C0221480
Disease	Depressive disorder	SLC6A1 SLC6A2 DRD1 DRD2 DRD5 NPSR1 GRPR	1.58e-06	289	58	7	C0011581
Disease	Mental Depression	SLC6A1 SLC6A2 DRD1 DRD2 NPSR1 GRPR	1.07e-05	254	58	6	C0011570
Disease	morphine dependence (biomarker_via_orthology)	DRD2 NPSR1	1.14e-05	3	58	2	DOID:2560 (biomarker_via_orthology)
Disease	nephrolithiasis (implicated_via_orthology)	SLC9A4 SLC9A1	3.78e-05	5	58	2	DOID:585 (implicated_via_orthology)
Disease	withdrawal disorder (biomarker_via_orthology)	SLC6A1 DRD1	3.78e-05	5	58	2	DOID:0060001 (biomarker_via_orthology)
Disease	heroin dependence (biomarker_via_orthology)	DRD1 DRD2	3.78e-05	5	58	2	DOID:9976 (biomarker_via_orthology)
Disease	Visual seizure	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0270824
Disease	Epileptic drop attack	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0270846
Disease	Generalized seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0234533
Disease	Clonic Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0234535
Disease	Vertiginous seizure	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0422855
Disease	Gustatory seizure	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0422854
Disease	Seizures, Somatosensory	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0422850
Disease	Olfactory seizure	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0422853
Disease	Seizures, Auditory	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0422852
Disease	Generalized Absence Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C4505436
Disease	Convulsive Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0751494
Disease	Seizures, Sensory	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0751496
Disease	Jacksonian Seizure	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0022333
Disease	Non-epileptic convulsion	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0751056
Disease	Atonic Absence Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0751123
Disease	Complex partial seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0149958
Disease	Single Seizure	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C0751110
Disease	Epileptic Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C4317109
Disease	Nonepileptic Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.76e-05	101	58	4	C3495874
Disease	Tonic Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.95e-05	102	58	4	C0270844
Disease	Absence Seizures	SLC6A1 SLC6A2 DRD1 DRD2	4.95e-05	102	58	4	C4316903
Disease	Convulsions	SLC6A1 SLC6A2 DRD1 DRD2	4.95e-05	102	58	4	C4048158
Disease	Seizures, Focal	SLC6A1 SLC6A2 DRD1 DRD2	5.34e-05	104	58	4	C0751495
Disease	Myoclonic Seizures	SLC6A1 SLC6A2 DRD1 DRD2	5.34e-05	104	58	4	C4317123
Disease	Tonic - clonic seizures	SLC6A1 SLC6A2 DRD1 DRD2	5.34e-05	104	58	4	C0494475
Disease	Pituitary carcinoma	DRD2 AGTR1	5.67e-05	6	58	2	C0346300
Disease	Seizures	SLC6A1 SLC6A2 PIGB DRD1 DRD2	7.01e-05	218	58	5	C0036572
Disease	Pituitary Neoplasms	DRD2 AGTR1	1.06e-04	8	58	2	C0032019
Disease	Tremor, Neonatal	ADRB2 CHRM4	1.35e-04	9	58	2	C0235843
Disease	Action Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234376
Disease	Passive Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234377
Disease	Static Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234378
Disease	Resting Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234379
Disease	Intermittent Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234372
Disease	Fine Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234373
Disease	Coarse Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234374
Disease	Massive Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234375
Disease	Persistent Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234370
Disease	Continuous Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234371
Disease	Darkness Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0234381
Disease	Involuntary Quiver	ADRB2 CHRM4	1.35e-04	9	58	2	C1527384
Disease	Tremor, Perioral	ADRB2 CHRM4	1.35e-04	9	58	2	C0235078
Disease	Nerve Tremors	ADRB2 CHRM4	1.35e-04	9	58	2	C0235083
Disease	Tremor, Limb	ADRB2 CHRM4	1.35e-04	9	58	2	C0235081
Disease	Tremor, Muscle	ADRB2 CHRM4	1.35e-04	9	58	2	C0235082
Disease	Senile Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0149840
Disease	Saturnine Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0040827
Disease	Pill Rolling Tremor	ADRB2 CHRM4	1.35e-04	9	58	2	C0751564
Disease	Tremor, Semirhythmic	ADRB2 CHRM4	1.35e-04	9	58	2	C0751565
Disease	Pituitary Adenoma	DRD2 AGTR1	1.35e-04	9	58	2	C0032000
Disease	depressive disorder (biomarker_via_orthology)	SLC6A2 DRD1 DRD2	1.49e-04	52	58	3	DOID:1596 (biomarker_via_orthology)
Disease	Alcoholic Intoxication, Chronic	SLC6A1 SLC6A2 DRD1 DRD2 NPSR1	1.84e-04	268	58	5	C0001973
Disease	Tremor	ADRB2 CHRM4	2.06e-04	11	58	2	C0040822
Disease	Parkinson's disease (implicated_via_orthology)	DRD1 DRD2 YIF1B ATP13A3	2.62e-04	157	58	4	DOID:14330 (implicated_via_orthology)
Disease	Schizophrenia	SLC6A1 SLC6A2 VRK2 DRD1 DRD2 ABCA13 NPSR1 CHRM4	3.18e-04	883	58	8	C0036341
Disease	Bipolar Disorder	SLC6A2 DRD1 DRD2 DRD5 ADRB2 ABCA13	3.44e-04	477	58	6	C0005586
Disease	Waxy flexibility	DRD1 DRD2	3.92e-04	15	58	2	C0233612
Disease	Dyskinesia, Drug-Induced	DRD1 DRD2	3.92e-04	15	58	2	C0013386
Disease	Dyskinesia, Medication-Induced	DRD1 DRD2	3.92e-04	15	58	2	C0751088
Disease	Catalepsy	DRD1 DRD2	3.92e-04	15	58	2	C0007370
Disease	Lipidemias	ADRB2 ADRB3	5.07e-04	17	58	2	C1706412
Disease	Hyperlipidemia	ADRB2 ADRB3	5.07e-04	17	58	2	C0020473
Disease	renovascular hypertension (biomarker_via_orthology)	SLC9A1 AGTR1	6.36e-04	19	58	2	DOID:1591 (biomarker_via_orthology)
Disease	sleep duration	DRD1 DRD2 GRM6 LMBRD1 KCNH5	7.27e-04	362	58	5	EFO_0005271
Disease	obesity (is_implicated_in)	DRD2 ADRB2 ADRB3	7.74e-04	91	58	3	DOID:9970 (is_implicated_in)
Disease	polycystic ovary syndrome (biomarker_via_orthology)	ADRB2 ADRB3	7.78e-04	21	58	2	DOID:11612 (biomarker_via_orthology)
Disease	Attention Deficit Disorder	DRD2 DRD5	8.55e-04	22	58	2	C0041671
Disease	depressive disorder (implicated_via_orthology)	DRD1 DRD5	8.55e-04	22	58	2	DOID:1596 (implicated_via_orthology)
Disease	Minimal Brain Dysfunction	DRD2 DRD5	8.55e-04	22	58	2	C1321905
Disease	Etat Marbre	DRD1 DRD2	9.36e-04	23	58	2	C0266487
Disease	Attention deficit hyperactivity disorder	DRD2 DRD5	1.02e-03	24	58	2	C1263846
Disease	traumatic brain injury (biomarker_via_orthology)	DRD1 DRD2	1.02e-03	24	58	2	DOID:0081292 (biomarker_via_orthology)
Disease	opioid use disorder	VRK2 DRD2 HS6ST3	1.05e-03	101	58	3	EFO_0010702
Disease	congestive heart failure (biomarker_via_orthology)	ADRB2 ADRB3 CHRM4	1.24e-03	107	58	3	DOID:6000 (biomarker_via_orthology)
Disease	Myocardial Failure	SLC9A1 ADRB3 AGTR1	1.34e-03	110	58	3	C1959583
Disease	Congestive heart failure	SLC9A1 ADRB3 AGTR1	1.34e-03	110	58	3	C0018802
Disease	Heart failure	SLC9A1 ADRB3 AGTR1	1.34e-03	110	58	3	C0018801
Disease	Left-Sided Heart Failure	SLC9A1 ADRB3 AGTR1	1.34e-03	110	58	3	C0023212
Disease	Heart Failure, Right-Sided	SLC9A1 ADRB3 AGTR1	1.34e-03	110	58	3	C0235527
Disease	Heart Decompensation	SLC9A1 ADRB3 AGTR1	1.34e-03	110	58	3	C1961112
Disease	Movement Disorders	DRD1 DRD2	1.49e-03	29	58	2	C0026650
Disease	Parkinson's disease (biomarker_via_orthology)	DRD1 DRD2	1.59e-03	30	58	2	DOID:14330 (biomarker_via_orthology)
Disease	proteinuria (implicated_via_orthology)	SLC9A1 AGTR1	1.59e-03	30	58	2	DOID:576 (implicated_via_orthology)
Disease	Alzheimer's disease (is_marker_for)	DRD1 DRD2 DRD5 AGTR1	1.65e-03	257	58	4	DOID:10652 (is_marker_for)
Disease	Hyperkinesia, Generalized	DRD1 DRD2	1.81e-03	32	58	2	C0751217
Disease	Hyperkinesia	DRD1 DRD2	1.81e-03	32	58	2	C3887506

Protein segments in the cluster

Peptide	Gene	Start	Entry
IAAFYLPVVIMTVLY	CHRM4	201	P08173
VSFYVPLVIMVFVYS	ADRB2	206	P07550
YMTPVILLVFALALY	ADCY6	896	O43306
VIFLYIFILFIMLYP	ATP13A3	1111	Q9H7F0
IYDMVFYLVPVAFSI	ABCA12	2036	Q86UK0
YIFVMIPTLYSIIFV	AGTR1	26	P30556
YMISFLPYIVLLVLH	ABCA13	3686	Q86UQ4
ISFYIPVAIMIVTYT	DRD1	201	P21728
VSFYLPLLVMLFVYA	ADRB3	211	P13945
LISFYIPVAIMIVTY	DRD5	231	P21918
HILPYFYIIYFTMLL	LBR	566	Q14739
ITIVVLMFGPSIYIY	OR4M2B	246	A0A0X1KG70
VFYTTVILMLNPLIY	OR8D4	276	Q8NGM9
VVSMIFVPSIYLYAR	OR4D2	246	P58180
LTVVVIFYGTILFMY	OR13C7	246	P0DN81
VTIFYGTIIFMYLQP	OR2G2	251	Q8NGZ5
MTIVAFLVYFIPLTI	NPSR1	211	Q6W5P4
FLVYFIPLTIISIMY	NPSR1	216	Q6W5P4
DYILITIIIMYFIFT	LMBRD1	366	Q9NUN5
ILILTFYTAIMVPYN	KCNH5	221	Q8NCM2
VFYSIITLMLNPLIY	OR4A16	271	Q8NH70
VLIFYVTVMGLTFIY	OR51B2	246	Q9Y5P1
ITIVVLMFGPSIYIY	OR4M1	246	Q8NGD0
ITIVVLMFGPSIYIY	OR4M2	246	Q8NGB6
KYFPYLVVIHTLIFM	LRRC8E	116	Q6NSJ5
LIIGYSTIYTMFPVF	ATP9A	876	O75110
PLFFLFLVVYIVTMV	OR8B3	26	Q8NGG8
TPVLTLLFVVIMYQY	HS6ST3	11	Q8IZP7
VVLLFYGTIMSPYFR	OR1F2P	246	Q96R84
MLLIPVTVISVSYYY	OR2T10	206	Q8NGZ9
AKMYSLFYTIIIPLL	OR5AC1	271	P0C628
SLGMLYVPKTYVILF	GRM6	831	O15303
LVFMVPFYIGYFIVS	GPR89A	86	B7ZAQ6
LVFMVPFYIGYFIVS	GPR89B	86	P0CG08
KILFYISIFSYPELM	CLLU1	66	Q5K131
LVFYVIPLSIISVYY	GRPR	216	P30550
YYLIQMYIPSLLIVI	GLRA2	256	P23416
VSFYVPFIVTLLVYI	DRD2	196	P14416
TLYFLVLLPFFMILV	CALCRL	6	Q16602
VIALIYFLPLAVMFV	TACR2	201	P21452
YFLPLAVMFVAYSVI	TACR2	206	P21452
FSYPFLVLQMYVLTL	DPY19L2P2	111	Q6ZN68
PVFFIFLLFYLLILM	OR2AT4	31	A6NND4
IFLFYITVIIMYIRP	OR5B17	246	Q8NGF7
PLFFLFLVIYIVTMV	OR8B2	26	Q96RD0
METVLTIIALFYYPL	PIGB	196	Q92521
MVYFLPIIFSILVVF	TAS2R33	1	P0DSN6
MVLVPIYVIYKFLST	SLC6A2	566	P23975
YFSATYPYIMLIILF	SLC6A1	241	P30531
YPYIMLIILFFRGVT	SLC6A1	246	P30531
IYYPMLVVILCIATY	LMBRD2	531	Q68DH5
LTSYKVIYVLPMLTI	LARS1	366	Q9P2J5
VFYTVVIPMLNSVIY	OR5L1	276	Q8NGL2
IEPLIVFMFSYLSYL	SLC9A4	301	Q6AI14
IIAMVVYTAYVFIPI	SPTSSB	41	Q8NFR3
FYTTVIPMLNLIIYS	OR5M8	276	Q8NGP6
PQMEIIFFVVFLIVY	OR5AR1	21	Q8NGP9
VTVTIFYGTLIFMYL	OR8U3	246	Q8NH85
FYMLIILPFLILLVF	SLC36A3	191	Q495N2
FFLIIYITMTYTRIP	CMTM8	86	Q8IZV2
FRKLIYYIIFSIIML	TMEM243	91	Q9BU79
DLYIPAMAFITYVLV	YIF1B	156	Q5BJH7
MTTQLPAYVAILLFY	VNN1	1	O95497
VFYVLSYLQPAMAVI	SLC35A5	111	Q9BS91
LIVYYPVFLVMTSSA	TAS2R9	241	Q9NYW1
IRVIEPLFVFLYSYM	SLC9A1	326	P19634
DVYYYRIIIPVLLML	VRK2	486	Q86Y07
LMVYFLILYIPYSVA	TAS2R4	231	Q9NYW5
YFPYLVLIHTLVFML	LRRC8C	126	Q8TDW0