Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

JAG2 ARSA CELSR3 MEGF6 MEGF8 DSG1 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8 STAB1

1.22e-097493312GO:0005509
GeneOntologyMolecularFunctioncargo receptor activity

SCARF1 MEGF10 LRP8 STAB1

1.14e-0585334GO:0038024
GeneOntologyMolecularFunctionNotch binding

JAG2 MEGF10 NOTCH1

1.17e-0527333GO:0005112
GeneOntologyMolecularFunctionscavenger receptor activity

SCARF1 MEGF10 STAB1

1.17e-0527333GO:0005044
GeneOntologyMolecularFunctionlipoprotein particle binding

SCARF1 LRP8 STAB1

2.60e-0535333GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

SCARF1 LRP8 STAB1

2.60e-0535333GO:0071814
GeneOntologyMolecularFunctionarylsulfatase activity

ARSH ARSA

2.38e-0414332GO:0004065
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP8 STAB1

3.13e-0416332GO:0005041
GeneOntologyMolecularFunctionsulfuric ester hydrolase activity

ARSH ARSA

3.55e-0417332GO:0008484
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

SCARF1 STAB1

3.99e-0418332GO:0030169
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP8 STAB1

5.45e-0421332GO:0030228
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MUC2 SSPOP LTBP4

3.64e-03188333GO:0005201
GeneOntologyMolecularFunctionenzyme inhibitor activity

FLCN UMODL1 SSPOP NOTCH1

5.51e-03435334GO:0004857
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADGRB2 SCARF1 CELSR3 TIE1 LTBP4 NOTCH1 LRP8

5.80e-031353337GO:0004888
GeneOntologyBiologicalProcessregulation of postsynaptic neurotransmitter receptor activity

SHISA9 NOTCH1 LRP8

2.27e-0617323GO:0098962
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

JAG2 NOTCH1

3.48e-056322GO:0060120
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

JAG2 NOTCH1

3.48e-056322GO:0009912
GeneOntologyBiologicalProcessapoptotic process involved in development

JAG2 MEGF10 NOTCH1

5.25e-0547323GO:1902742
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

TGFB1I1 FLCN MEGF8 LTBP4 ITGB6 NOTCH1

5.49e-05445326GO:0141091
GeneOntologyBiologicalProcessregulation of pro-B cell differentiation

FLCN NOTCH1

6.49e-058322GO:2000973
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

TGFB1I1 FLCN MEGF8 LTBP4 ITGB6 NOTCH1

8.54e-05482326GO:0007178
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor activity

SHISA9 NOTCH1 LRP8

8.89e-0556323GO:0099601
GeneOntologyBiologicalProcessextracellular matrix assembly

TIE1 LTBP4 NOTCH1

1.04e-0459323GO:0085029
GeneOntologyBiologicalProcessregulation of lymphoid progenitor cell differentiation

FLCN NOTCH1

1.52e-0412322GO:1905456
GeneOntologyBiologicalProcesspro-B cell differentiation

FLCN NOTCH1

1.80e-0413322GO:0002328
GeneOntologyBiologicalProcesscell-cell adhesion

SCARF1 CELSR3 TENM3 DSG1 ITGB6 MEGF11 MEGF10 NOTCH1

1.84e-041077328GO:0098609
GeneOntologyBiologicalProcesscell recognition

ARSA CELSR3 MEGF8 MEGF10

2.40e-04198324GO:0008037
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

TGFB1I1 FLCN MEGF8 LTBP4 ITGB6 NOTCH1 LRP8

2.69e-04850327GO:0071363
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

ADGRB2 TIE1 ITGB6 PRAMEF22 MEGF11 NOTCH1 NOTCH3 LRP8 STAB1

3.09e-041483329GO:0048646
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

TGFB1I1 JAG2 CSMD1 MEGF8 TIE1 NOTCH1

3.32e-04619326GO:0002009
GeneOntologyBiologicalProcessresponse to growth factor

TGFB1I1 FLCN MEGF8 LTBP4 ITGB6 NOTCH1 LRP8

3.39e-04883327GO:0070848
GeneOntologyBiologicalProcessneuron fate commitment

JAG2 NOTCH1 NOTCH3

3.76e-0491323GO:0048663
GeneOntologyBiologicalProcessartery morphogenesis

MEGF8 NOTCH1 NOTCH3

3.88e-0492323GO:0048844
GeneOntologyBiologicalProcessnegative regulation of developmental process

ADGRB2 TGFB1I1 FLCN TIE1 PRAMEF22 NOTCH1 NOTCH3 STAB1

4.30e-041220328GO:0051093
GeneOntologyBiologicalProcessskeletal muscle cell differentiation

MEGF10 NOTCH1 ZNF689

4.39e-0496323GO:0035914
GeneOntologyBiologicalProcesslymphoid progenitor cell differentiation

FLCN NOTCH1

7.40e-0426322GO:0002320
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

TGFB1I1 FLCN NOTCH1

7.44e-04115323GO:0090100
GeneOntologyBiologicalProcesssecondary palate development

JAG2 ITGB6

7.99e-0427322GO:0062009
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

TGFB1I1 FLCN LTBP4 ITGB6

8.40e-04276324GO:0007179
GeneOntologyBiologicalProcessneuron projection fasciculation

CELSR3 MEGF8

8.60e-0428322GO:0106030
GeneOntologyBiologicalProcessaxonal fasciculation

CELSR3 MEGF8

8.60e-0428322GO:0007413
GeneOntologyBiologicalProcesstissue morphogenesis

TGFB1I1 JAG2 CSMD1 MEGF8 TIE1 NOTCH1

9.14e-04750326GO:0048729
GeneOntologyBiologicalProcessregulation of extracellular matrix assembly

TIE1 NOTCH1

9.22e-0429322GO:1901201
GeneOntologyBiologicalProcessaxon guidance

CELSR3 MEGF8 NOTCH1 NOTCH3

9.46e-04285324GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

CELSR3 MEGF8 NOTCH1 NOTCH3

9.59e-04286324GO:0097485
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH1 NOTCH3

9.87e-0430322GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH1 NOTCH3

1.05e-0331322GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH1 NOTCH3

1.05e-0331322GO:0061437
GeneOntologyBiologicalProcesstube development

ADGRB2 CSMD1 MEGF8 TIE1 ITGB6 NOTCH1 NOTCH3 STAB1

1.08e-031402328GO:0035295
GeneOntologyBiologicalProcessregulation of signaling receptor activity

SHISA9 NOTCH1 LRP8

1.09e-03131323GO:0010469
GeneOntologyBiologicalProcessapoptotic process involved in morphogenesis

JAG2 NOTCH1

1.12e-0332322GO:0060561
GeneOntologyBiologicalProcessartery development

MEGF8 NOTCH1 NOTCH3

1.13e-03133323GO:0060840
GeneOntologyBiologicalProcessfemale gonad development

CSMD1 UMODL1 NOTCH1

1.26e-03138323GO:0008585
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

SCARF1 CELSR3 TENM3 DSG1

1.34e-03313324GO:0098742
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

TGFB1I1 FLCN

1.34e-0335322GO:1903846
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

TGFB1I1 FLCN

1.34e-0335322GO:0030511
GeneOntologyBiologicalProcessdevelopment of primary female sexual characteristics

CSMD1 UMODL1 NOTCH1

1.37e-03142323GO:0046545
GeneOntologyBiologicalProcessblood vessel morphogenesis

ADGRB2 MEGF8 TIE1 NOTCH1 NOTCH3 STAB1

1.42e-03817326GO:0048514
GeneOntologyBiologicalProcesstube morphogenesis

ADGRB2 CSMD1 MEGF8 TIE1 NOTCH1 NOTCH3 STAB1

1.43e-031125327GO:0035239
GeneOntologyBiologicalProcessaortic valve morphogenesis

TIE1 NOTCH1

1.67e-0339322GO:0003180
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

TGFB1I1 FLCN LTBP4 ITGB6

1.74e-03336324GO:0071560
GeneOntologyBiologicalProcesscell fate commitment

TGFB1I1 JAG2 NOTCH1 NOTCH3

1.77e-03338324GO:0045165
GeneOntologyBiologicalProcessfemale sex differentiation

CSMD1 UMODL1 NOTCH1

1.82e-03157323GO:0046660
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

TGFB1I1 FLCN LTBP4 ITGB6

1.87e-03343324GO:0071559
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

TGFB1I1 FLCN MEGF8 TIE1 LTBP4 ITGB6 NOTCH1

1.93e-031186327GO:0007167
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

TGFB1I1 FLCN LTBP4 NOTCH1

1.95e-03347324GO:0090092
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

JAG2 CSMD1 DSG1 UMODL1 TESK1 PRAMEF22 NOTCH1

2.01e-031194327GO:0048609
GeneOntologyBiologicalProcessin utero embryonic development

JAG2 FLCN TIE1 PRAMEF22 NOTCH1

2.09e-03596325GO:0001701
GeneOntologyBiologicalProcessaortic valve development

TIE1 NOTCH1

2.31e-0346322GO:0003176
GeneOntologyBiologicalProcessregulation of hematopoietic progenitor cell differentiation

FLCN NOTCH1

2.31e-0346322GO:1901532
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

TENM3 MEGF11 NOTCH1

2.33e-03171323GO:0048593
GeneOntologyBiologicalProcesschordate embryonic development

JAG2 FLCN MEGF8 TIE1 PRAMEF22 NOTCH1

2.40e-03906326GO:0043009
GeneOntologyBiologicalProcessregulation of nervous system process

SHISA9 NOTCH1 LRP8

2.49e-03175323GO:0031644
GeneOntologyBiologicalProcessnegative regulation of angiogenesis

ADGRB2 TIE1 STAB1

2.49e-03175323GO:0016525
GeneOntologyBiologicalProcessnegative regulation of cold-induced thermogenesis

FLCN NOTCH1

2.52e-0348322GO:0120163
GeneOntologyBiologicalProcessnegative regulation of blood vessel morphogenesis

ADGRB2 TIE1 STAB1

2.61e-03178323GO:2000181
GeneOntologyBiologicalProcessnegative regulation of vasculature development

ADGRB2 TIE1 STAB1

2.69e-03180323GO:1901343
GeneOntologyBiologicalProcessblood vessel development

ADGRB2 MEGF8 TIE1 NOTCH1 NOTCH3 STAB1

2.72e-03929326GO:0001568
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

JAG2 FLCN MEGF8 TIE1 PRAMEF22 NOTCH1

2.72e-03929326GO:0009792
GeneOntologyBiologicalProcesssemi-lunar valve development

TIE1 NOTCH1

2.73e-0350322GO:1905314
GeneOntologyCellularComponentpostsynaptic density membrane

SHISA9 CELSR3 NOTCH1 LRP8

1.19e-04157344GO:0098839
GeneOntologyCellularComponentpostsynaptic specialization membrane

SHISA9 CELSR3 NOTCH1 LRP8

3.07e-04201344GO:0099634
GeneOntologyCellularComponentreceptor complex

SHISA9 TIE1 ITGB6 NOTCH1 NOTCH3 LRP8

3.11e-04581346GO:0043235
GeneOntologyCellularComponentcollagen-containing extracellular matrix

TGFB1I1 MEGF6 MUC2 SSPOP LTBP4

1.56e-03530345GO:0062023
GeneOntologyCellularComponentglutamatergic synapse

ADGRB2 SHISA9 CELSR3 TENM3 NOTCH1 LRP8

1.84e-03817346GO:0098978
GeneOntologyCellularComponentsynaptic membrane

SHISA9 CELSR3 TENM3 NOTCH1 LRP8

2.36e-03583345GO:0097060
GeneOntologyCellularComponentextracellular matrix

TGFB1I1 MEGF6 MUC2 SSPOP LTBP4

3.92e-03656345GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

TGFB1I1 MEGF6 MUC2 SSPOP LTBP4

3.97e-03658345GO:0030312
GeneOntologyCellularComponentpostsynaptic membrane

SHISA9 CELSR3 NOTCH1 LRP8

4.07e-03405344GO:0045211
GeneOntologyCellularComponentacrosomal vesicle

ARSA PRAMEF22 NOTCH1

4.51e-03206343GO:0001669
DomainEGF_1

SCARF1 JAG2 CELSR3 MEGF6 MEGF8 TENM3 TIE1 UMODL1 SSPOP LTBP4 ITGB6 MEGF11 MEGF10 NOTCH1 NOTCH3 LRP8 STAB1

1.12e-232553317PS00022
DomainEGF_2

SCARF1 JAG2 CELSR3 MEGF6 MEGF8 TENM3 TIE1 UMODL1 SSPOP LTBP4 ITGB6 MEGF11 MEGF10 NOTCH1 NOTCH3 LRP8 STAB1

2.18e-232653317PS01186
DomainEGF_3

SCARF1 JAG2 CELSR3 MEGF6 MEGF8 TENM3 TIE1 UMODL1 SSPOP LTBP4 MEGF11 MEGF10 NOTCH1 NOTCH3 LRP8 STAB1

2.28e-222353316PS50026
DomainEGF-like_CS

SCARF1 JAG2 CELSR3 MEGF6 MEGF8 TENM3 TIE1 UMODL1 LTBP4 ITGB6 MEGF11 MEGF10 NOTCH1 NOTCH3 LRP8 STAB1

1.26e-212613316IPR013032
DomainEGF

SCARF1 JAG2 CELSR3 MEGF6 MEGF8 TENM3 TIE1 UMODL1 LTBP4 MEGF11 MEGF10 NOTCH1 NOTCH3 LRP8 STAB1

1.70e-202353315SM00181
DomainEGF_extracell

SCARF1 JAG2 MEGF6 TENM3 TIE1 ITGB6 MEGF11 MEGF10 NOTCH1 NOTCH3 STAB1

2.61e-20603311IPR013111
DomainEGF_2

SCARF1 JAG2 MEGF6 TENM3 TIE1 ITGB6 MEGF11 MEGF10 NOTCH1 NOTCH3 STAB1

2.61e-20603311PF07974
DomainEGF-like_dom

SCARF1 JAG2 CELSR3 MEGF6 MEGF8 TENM3 TIE1 UMODL1 LTBP4 MEGF11 MEGF10 NOTCH1 NOTCH3 LRP8 STAB1

4.10e-202493315IPR000742
DomainGrowth_fac_rcpt_

SCARF1 JAG2 MEGF6 MEGF8 TIE1 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8 STAB1

1.60e-151563311IPR009030
DomainEGF_CA

JAG2 CELSR3 MEGF6 MEGF8 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8 STAB1

7.92e-151223310SM00179
DomainEGF-like_Ca-bd_dom

JAG2 CELSR3 MEGF6 MEGF8 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8 STAB1

9.36e-151243310IPR001881
DomainASX_HYDROXYL

JAG2 CELSR3 MEGF6 MEGF8 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8

8.68e-14100339PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 CELSR3 MEGF6 MEGF8 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8

1.49e-13106339IPR000152
DomainLaminin_EGF

SCARF1 CELSR3 MEGF6 MEGF8 MEGF11 MEGF10 STAB1

1.77e-1335337PF00053
DomainLaminin_EGF

SCARF1 CELSR3 MEGF6 MEGF8 MEGF11 MEGF10 STAB1

3.30e-1338337IPR002049
DomainEGF_CA

JAG2 MEGF6 MEGF8 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8

1.83e-1286338PF07645
DomainEGF_Ca-bd_CS

JAG2 MEGF6 MEGF8 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8

4.92e-1297338IPR018097
DomainEGF_CA

JAG2 MEGF6 MEGF8 UMODL1 LTBP4 NOTCH1 NOTCH3 LRP8

5.82e-1299338PS01187
DomainhEGF

JAG2 MEGF6 MEGF11 MEGF10 NOTCH1 NOTCH3

6.89e-1228336PF12661
DomainEGF_Lam

CELSR3 MEGF6 MEGF8 MEGF11 MEGF10 STAB1

2.94e-1135336SM00180
DomainEGF

JAG2 CELSR3 MEGF6 TIE1 NOTCH1 NOTCH3 LRP8 STAB1

4.13e-11126338PF00008
DomainEMI

MEGF6 UMODL1 SSPOP MEGF11 MEGF10

7.64e-1117335PS51041
DomainEMI_domain

MEGF6 UMODL1 MEGF11 MEGF10

1.45e-0816334IPR011489
DomainVWC_out

JAG2 MUC2 SSPOP

4.78e-0619333SM00215
DomainDUF3454

NOTCH1 NOTCH3

9.07e-063332PF11936
DomainDUF3454_notch

NOTCH1 NOTCH3

9.07e-063332IPR024600
DomainDUF3454

NOTCH1 NOTCH3

9.07e-063332SM01334
DomainNOD

NOTCH1 NOTCH3

1.81e-054332PF06816
DomainNotch

NOTCH1 NOTCH3

1.81e-054332IPR008297
DomainNODP

NOTCH1 NOTCH3

1.81e-054332PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH3

1.81e-054332IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH3

1.81e-054332IPR010660
DomainNOD

NOTCH1 NOTCH3

1.81e-054332SM01338
DomainNODP

NOTCH1 NOTCH3

1.81e-054332SM01339
DomainEGF_LAM_2

CELSR3 MEGF8 STAB1

1.98e-0530333PS50027
DomainEGF_LAM_1

CELSR3 MEGF8 STAB1

1.98e-0530333PS01248
DomainLNR

NOTCH1 NOTCH3

3.02e-055332PS50258
DomainVWFC_1

JAG2 MUC2 SSPOP

3.45e-0536333PS01208
DomainVWC

JAG2 MUC2 SSPOP

4.06e-0538333SM00214
DomainVWFC_2

JAG2 MUC2 SSPOP

4.06e-0538333PS50184
DomainVWF_dom

JAG2 MUC2 SSPOP

5.50e-0542333IPR001007
DomainNotch_dom

NOTCH1 NOTCH3

6.32e-057332IPR000800
DomainNotch

NOTCH1 NOTCH3

6.32e-057332PF00066
DomainNL

NOTCH1 NOTCH3

6.32e-057332SM00004
DomainPSI_integrin

MEGF8 ITGB6

1.08e-049332PF17205
DomainIntegin_beta_N

MEGF8 ITGB6

1.08e-049332IPR033760
DomainGAIN_dom_N

ADGRB2 CELSR3

1.65e-0411332IPR032471
DomainGAIN

ADGRB2 CELSR3

1.65e-0411332PF16489
DomainEGF_3

MEGF8 STAB1

1.98e-0412332PF12947
DomainTIL

MUC2 SSPOP

1.98e-0412332PF01826
DomainEGF_dom

MEGF8 STAB1

1.98e-0412332IPR024731
DomainC8

MUC2 SSPOP

1.98e-0412332PF08742
DomainUnchr_dom_Cys-rich

MUC2 SSPOP

2.33e-0413332IPR014853
DomainC8

MUC2 SSPOP

2.33e-0413332SM00832
DomainTIL_dom

MUC2 SSPOP

2.72e-0414332IPR002919
DomainVWFD

MUC2 SSPOP

3.58e-0416332PS51233
DomainVWD

MUC2 SSPOP

3.58e-0416332SM00216
DomainSulfatase_CS

ARSH ARSA

3.58e-0416332IPR024607
DomainVWF_type-D

MUC2 SSPOP

3.58e-0416332IPR001846
DomainVWD

MUC2 SSPOP

3.58e-0416332PF00094
DomainSULFATASE_1

ARSH ARSA

4.05e-0417332PS00523
DomainSULFATASE_2

ARSH ARSA

4.05e-0417332PS00149
DomainSulfatase

ARSH ARSA

4.55e-0418332PF00884
DomainCTCK_1

MUC2 SSPOP

4.55e-0418332PS01185
DomainSulfatase_N

ARSH ARSA

4.55e-0418332IPR000917
DomainCys_knot_C

MUC2 SSPOP

8.85e-0425332IPR006207
DomainCTCK_2

MUC2 SSPOP

8.85e-0425332PS01225
DomainHormR

ADGRB2 CELSR3

8.85e-0425332SM00008
DomainHRM

ADGRB2 CELSR3

1.11e-0328332PF02793
DomainAlkaline_phosphatase_core

ARSH ARSA

1.36e-0331332IPR017850
DomainAlkaline_Pase-like_a/b/a

ARSH ARSA

1.36e-0331332IPR017849
Domain-

ARSH ARSA

1.36e-03313323.40.720.10
DomainGPS

ADGRB2 CELSR3

1.64e-0334332SM00303
DomainGPS

ADGRB2 CELSR3

1.74e-0335332PF01825
DomainGPS

ADGRB2 CELSR3

1.84e-0336332PS50221
DomainGPS

ADGRB2 CELSR3

1.94e-0337332IPR000203
Domain-

TENM3 LRP8

2.15e-03393322.120.10.30
DomainG_PROTEIN_RECEP_F2_1

ADGRB2 CELSR3

2.26e-0340332PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRB2 CELSR3

2.26e-0340332PS50227
DomainGPCR_2_extracellular_dom

ADGRB2 CELSR3

2.26e-0340332IPR001879
DomainLDLR_class-A_CS

SSPOP LRP8

2.26e-0340332IPR023415
DomainPSI

MEGF8 ITGB6

2.73e-0344332IPR016201
DomainLdl_recept_a

SSPOP LRP8

2.86e-0345332PF00057
DomainPSI

MEGF8 ITGB6

2.98e-0346332SM00423
Domain-

SSPOP LRP8

2.98e-03463324.10.400.10
Domain6-blade_b-propeller_TolB-like

TENM3 LRP8

2.98e-0346332IPR011042
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH3

1.39e-0613253M47423
PathwayPID_NOTCH_PATHWAY

JAG2 SSPOP NOTCH1 NOTCH3

3.28e-0659254M17
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 NOTCH1 NOTCH3

1.40e-0527253M39545
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH3

3.01e-055252M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

3.01e-055252MM14733
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 NOTCH1 NOTCH3

4.32e-0539253MM14604
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH3

4.51e-056252M27068
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 NOTCH1

6.31e-057252M27199
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3

6.31e-057252MM14734
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 NOTCH1 NOTCH3

6.66e-0545253M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH3

7.11e-0546253MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH3

7.59e-0547253M7946
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 NOTCH1 NOTCH3

8.60e-0549253M618
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1

1.35e-0410252MM14849
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH3

1.64e-0411252M47865
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 NOTCH1 NOTCH3

1.66e-0461253M39540
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH3

1.97e-0412252M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH3

1.97e-0412252M47533
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP NOTCH1 NOTCH3

2.29e-0468253M27303
PathwayREACTOME_THE_ACTIVATION_OF_ARYLSULFATASES

ARSH ARSA

2.33e-0413252M663
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH3

2.33e-0413252M47534
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1

3.13e-0415252M27202
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1

3.57e-0416252M47424
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH3

3.98e-0482253MM15922
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG2 NOTCH1

4.04e-0417252M39389
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

4.54e-0418252M614
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1

4.54e-0418252MM14775
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 NOTCH3

5.07e-0419252MM15594
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3

7.47e-0423252MM14954
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH3

8.14e-0424252M11190
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH3

8.83e-0425252M27880
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH3

8.83e-0425252M27879
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3

1.11e-0328252M6177
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

JAG2 NOTCH1 NOTCH3

1.15e-03118253M39852
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1

1.36e-0331252M592
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP4 ITGB6

1.45e-0332252MM14854
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH3

1.64e-0334252M39390
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 NOTCH3

1.94e-0337252M39506
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP4 ITGB6

1.94e-0337252M27134
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

SSPOP NOTCH1 NOTCH3

2.00e-03143253M27275
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP4 ITGB6

2.04e-0338252MM14874
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP4 ITGB6

2.15e-0339252MM14601
PathwayREACTOME_GLYCOSPHINGOLIPID_CATABOLISM

ARSH ARSA

2.15e-0339252M48042
PathwayWP_BREAST_CANCER_PATHWAY

JAG2 NOTCH1 NOTCH3

2.46e-03154253M39739
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP4 ITGB6

2.73e-0344252M26969
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

JAG2 NOTCH1 NOTCH3

2.80e-03161253M39770
PathwayPID_PS1_PATHWAY

SSPOP NOTCH1

2.98e-0346252M70
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP4 ITGB6

3.11e-0347252M646
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

NOTCH1 LRP8

4.54e-0357252M48326
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

ARSH ARSA

4.70e-0358252M576
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1

4.70e-0358252M29616
PathwayREACTOME_GAMMA_CARBOXYLATION_HYPUSINYLATION_HYDROXYLATION_AND_ARYLSULFATASE_ACTIVATION

ARSH ARSA

5.18e-0361252M26993
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

MEGF6 TESK1

7.35e-0373252MM15126
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1

7.54e-0374252M616
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

LTBP4 ITGB6

8.14e-0377252MM14670
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 NOTCH1 NOTCH3

9.09e-03246253M10189
PathwayREACTOME_DISEASES_OF_METABOLISM

SSPOP NOTCH1 NOTCH3

9.50e-03250253M27554
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_STAGE_3_OF_3

DSG1 NOTCH1

1.03e-0287252M39465
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

MEGF6 LTBP4 ITGB6

1.03e-02258253MM14572
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ADGRB2 TGFB1I1 JAG2 MEGF6 MEGF8 LTBP4 MEGF11 MEGF10 NOTCH1 NOTCH3 STAB1

5.03e-12560351121653829
Pubmed

Activation of Notch signaling in human tongue carcinoma.

JAG2 NOTCH1 NOTCH3

3.73e-09435320819128
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

JAG2 MUC2 NOTCH3

3.73e-09435322691042
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

JAG2 NOTCH1 NOTCH3

3.73e-09435320040020
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

JAG2 NOTCH1 NOTCH3

9.32e-09535311006133
Pubmed

Functional diversity of notch family genes in fetal lung development.

JAG2 NOTCH1 NOTCH3

9.32e-09535315064243
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

JAG2 NOTCH1 NOTCH3

3.26e-08735310383933
Pubmed

Human ligands of the Notch receptor.

JAG2 NOTCH1 NOTCH3

3.26e-08735310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 NOTCH1 NOTCH3

3.26e-08735312846471
Pubmed

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.

JAG2 NOTCH1 NOTCH3

3.26e-08735316169548
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

JAG2 NOTCH1 NOTCH3

5.21e-08835322652674
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 NOTCH1 NOTCH3

5.21e-0883539858718
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 NOTCH1 NOTCH3

5.21e-08835311044610
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

CELSR3 MEGF6 MEGF8

7.81e-0893539693030
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 NOTCH1 NOTCH3

7.81e-08935311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 NOTCH1 NOTCH3

7.81e-08935316245338
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

JAG2 MUC2 NOTCH1 NOTCH3

8.47e-084135422675208
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 NOTCH1 NOTCH3

1.11e-071035323665443
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

JAG2 MEGF6 MEGF8 LTBP4 NOTCH1

1.24e-0711835521078624
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

TGFB1I1 JAG2 MEGF6 MEGF8 SSPOP LTBP4 MEGF11 NOTCH1

1.29e-0760835816713569
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH1 NOTCH3

1.53e-071135316607638
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 NOTCH1 NOTCH3

1.53e-071135310878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 NOTCH1 NOTCH3

1.53e-071135312866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 NOTCH1 NOTCH3

2.04e-071235315465494
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 NOTCH1 NOTCH3

2.65e-071335331202705
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 NOTCH1 NOTCH3

2.65e-071335311578869
Pubmed

Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.

JAG2 NOTCH1 NOTCH3

3.37e-071435328192800
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 NOTCH1 NOTCH3

3.37e-071435314757642
Pubmed

GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.

JAG2 TIE1 NOTCH1 NOTCH3

3.76e-075935421421844
Pubmed

Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

JAG2 NOTCH1 NOTCH3

4.21e-071535317194759
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 NOTCH1 NOTCH3

4.21e-071535312971992
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

JAG2 NOTCH1 NOTCH3

4.21e-07153539291577
Pubmed

Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.

TENM3 MEGF11 MEGF10

4.21e-071535331812516
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 NOTCH1 NOTCH3

4.21e-071535312167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 NOTCH1 NOTCH3

4.21e-071535316914494
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 NOTCH1 NOTCH3

5.18e-071635312617809
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 NOTCH1 NOTCH3

5.18e-071635310842072
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 NOTCH1 NOTCH3

5.18e-071635317273555
Pubmed

The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.

JAG2 NOTCH1 NOTCH3

5.18e-071635327641601
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG2 NOTCH1 NOTCH3

5.18e-071635332161758
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 NOTCH1 NOTCH3

6.29e-071735318694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 NOTCH1 NOTCH3

6.29e-071735315821257
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 NOTCH1 NOTCH3

7.54e-071835318093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG2 NOTCH1 NOTCH3

7.54e-071835315689374
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG2 NOTCH1 NOTCH3

8.95e-071935316518823
Pubmed

Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes.

JAG2 NOTCH1

9.84e-07235211700865
Pubmed

Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature.

NOTCH1 NOTCH3

9.84e-07235234878922
Pubmed

[Expression and significance of Notch-1 and Jagged-2 in patients with Hirschsprung disease].

JAG2 NOTCH1

9.84e-07235222030773
Pubmed

The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance.

NOTCH1 NOTCH3

9.84e-07235226634853
Pubmed

The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern.

MEGF11 MEGF10

9.84e-07235217498693
Pubmed

A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.

NOTCH1 NOTCH3

9.84e-07235221191019
Pubmed

Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk.

NOTCH1 NOTCH3

9.84e-07235217881497
Pubmed

Downregulation of Notch-1/Jagged-2 in human colon tissues from Hirschsprung disease patients.

JAG2 NOTCH1

9.84e-07235221892607
Pubmed

Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.

JAG2 NOTCH1

9.84e-07235223074278
Pubmed

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.

NOTCH1 NOTCH3

9.84e-07235229023469
Pubmed

Nuclear Notch3 expression is associated with tumor recurrence in patients with stage II and III colorectal cancer.

NOTCH1 NOTCH3

9.84e-07235224728738
Pubmed

Distinct roles for Notch1 and Notch3 in human adipose-derived stem/stromal cell adipogenesis.

NOTCH1 NOTCH3

9.84e-07235233021719
Pubmed

Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.

NOTCH1 NOTCH3

9.84e-07235226563570
Pubmed

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.

NOTCH1 NOTCH3

9.84e-07235214595837
Pubmed

Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.

NOTCH1 NOTCH3

9.84e-07235221768299
Pubmed

Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.

NOTCH1 NOTCH3

9.84e-07235225700162
Pubmed

Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.

NOTCH1 NOTCH3

9.84e-07235218069660
Pubmed

Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors.

NOTCH1 NOTCH3

9.84e-07235216507912
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ADGRB2 JAG2 FLCN CELSR3 MEGF6 MEGF8 TESK1 LTBP4 NOTCH1

1.07e-06110535935748872
Pubmed

Canonical notch signaling functions as a commitment switch in the epidermal lineage.

ITGB6 NOTCH1 NOTCH3

1.23e-062135317079689
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG2 NOTCH1 NOTCH3

1.23e-062135328656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

JAG2 NOTCH1 NOTCH3

1.23e-062135314702043
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

JAG2 NOTCH1 NOTCH3

1.42e-062235321750033
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

JAG2 NOTCH1 NOTCH3

1.63e-062335314701881
Pubmed

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

ITGB6 NOTCH1 NOTCH3

1.63e-062335319897741
Pubmed

Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.

JAG2 NOTCH1 NOTCH3

1.63e-062335324337118
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

JAG2 NOTCH1 NOTCH3

1.86e-062435321420948
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

JAG2 FLCN ARSA CELSR3 MEGF8 TENM3 NOTCH1 NOTCH3 LRP8

2.13e-06120135935696571
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

JAG2 NOTCH1 NOTCH3

2.39e-062635319369401
Pubmed

Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro.

NOTCH1 NOTCH3

2.95e-06335215987768
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH1 NOTCH3

2.95e-0633527615640
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH3

2.95e-06335225846406
Pubmed

Sequential expressions of Notch1, Jagged2 and Math1 in molar tooth germ of mouse.

JAG2 NOTCH1

2.95e-06335219181188
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH1 NOTCH3

2.95e-0633527918097
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH1 NOTCH3

2.95e-0633528645602
Pubmed

Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression.

NOTCH1 NOTCH3

2.95e-06335231346528
Pubmed

PD-L1 and Notch as novel biomarkers in pancreatic sarcomatoid carcinoma: a pilot study.

NOTCH1 NOTCH3

2.95e-06335234846251
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH1 NOTCH3

2.95e-06335221471519
Pubmed

Smooth muscle Notch1 mediates neointimal formation after vascular injury.

NOTCH1 NOTCH3

2.95e-06335219433762
Pubmed

Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.

MEGF10 NOTCH1

2.95e-06335228498977
Pubmed

ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.

JAG2 NOTCH1

2.95e-06335238485033
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH1 NOTCH3

2.95e-06335227697639
Pubmed

NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.

NOTCH1 NOTCH3

2.95e-06335220801121
Pubmed

Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.

NOTCH1 NOTCH3

2.95e-06335218483410
Pubmed

Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.

JAG2 NOTCH1

2.95e-06335218458347
Pubmed

KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.

NOTCH1 NOTCH3

2.95e-06335234854382
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH1 NOTCH3

2.95e-06335229767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH1 NOTCH3

2.95e-0633527698746
Pubmed

Hepatitis B virus X protein and hypoxia‑inducible factor-1α stimulate Notch gene expression in liver cancer cells.

NOTCH1 NOTCH3

2.95e-06335227840976
Pubmed

The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model.

JAG2 NOTCH1

2.95e-06335237330998
Pubmed

Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells.

NOTCH1 NOTCH3

2.95e-06335233664344
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

ITGB6 NOTCH1 NOTCH3 LRP8

3.27e-0610135423382219
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

JAG2 NOTCH1 NOTCH3

3.35e-062935325535917
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

JAG2 NOTCH1 NOTCH3

3.35e-062935321402740
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

JAG2 NOTCH1 NOTCH3

3.72e-063035324552588
InteractionNTN5 interactions

JAG2 LTBP4 NOTCH1 NOTCH3

7.00e-0824344int:NTN5
InteractionMBD1 interactions

JAG2 MEGF6 LTBP4 NOTCH1 NOTCH3

1.82e-0777345int:MBD1
InteractionZNF74 interactions

JAG2 LTBP4 NOTCH1 NOTCH3

3.02e-0734344int:ZNF74
InteractionATN1 interactions

JAG2 MEGF6 MEGF8 SSPOP LTBP4 MEGF11

6.38e-07187346int:ATN1
InteractionMFAP5 interactions

JAG2 MEGF6 LTBP4 NOTCH3

1.73e-0652344int:MFAP5
InteractionHOXA1 interactions

TGFB1I1 JAG2 MEGF6 MEGF8 LTBP4 NOTCH1 NOTCH3

1.81e-06356347int:HOXA1
InteractionCACNA1A interactions

JAG2 MEGF6 MEGF8 LTBP4 NOTCH1

1.88e-06123345int:CACNA1A
InteractionGFI1B interactions

JAG2 MEGF6 MEGF8 LTBP4 NOTCH1

3.09e-06136345int:GFI1B
InteractionFBXO2 interactions

JAG2 CELSR3 MEGF8 TENM3 LTBP4 NOTCH1 NOTCH3

4.66e-06411347int:FBXO2
InteractionNOTCH2 interactions

JAG2 UMODL1 LTBP4 ZNF446 NOTCH1 ZNF689 NOTCH3

5.63e-06423347int:NOTCH2
InteractionZNF707 interactions

LTBP4 NOTCH1 ZNF689 NOTCH3

9.27e-0679344int:ZNF707
InteractionSHANK3 interactions

JAG2 MEGF6 LTBP4 MEGF11 MEGF10 NOTCH1 NOTCH3

1.59e-05496347int:SHANK3
InteractionEDN3 interactions

JAG2 ARSA MEGF8 NOTCH1

3.20e-05108344int:EDN3
InteractionATXN7 interactions

JAG2 MEGF6 MEGF8 LTBP4

3.31e-05109344int:ATXN7
InteractionPSG8 interactions

CELSR3 MEGF8 TENM3

4.48e-0541343int:PSG8
InteractionJAG1 interactions

JAG2 NOTCH1 NOTCH3

4.48e-0541343int:JAG1
InteractionIGSF5 interactions

NOTCH1 NOTCH3

2.48e-0414342int:IGSF5
InteractionIGFL3 interactions

JAG2 NOTCH1 NOTCH3

2.73e-0475343int:IGFL3
InteractionMAML2 interactions

NOTCH1 NOTCH3

3.70e-0417342int:MAML2
InteractionSIRPD interactions

JAG2 MEGF8 NOTCH1

4.08e-0486343int:SIRPD
InteractionMAML3 interactions

NOTCH1 NOTCH3

5.15e-0420342int:MAML3
InteractionTOP3B interactions

ADGRB2 JAG2 FLCN CELSR3 MEGF6 MEGF8 TESK1 LTBP4 NOTCH1

5.63e-041470349int:TOP3B
InteractionCASR interactions

NOTCH1 NOTCH3

6.25e-0422342int:CASR
InteractionNUFIP2 interactions

MEGF6 LTBP4 MEGF11 NOTCH3 STAB1

6.28e-04417345int:NUFIP2
InteractionAPBA1 interactions

TRAPPC14 NOTCH1 LRP8

6.91e-04103343int:APBA1
InteractionJAG2 interactions

JAG2 NOTCH1 NOTCH3

8.37e-04110343int:JAG2
InteractionADAM32 interactions

JAG2 NOTCH3

8.75e-0426342int:ADAM32
InteractionNOTCH3 interactions

JAG2 NOTCH1 NOTCH3

9.05e-04113343int:NOTCH3
Cytoband7q36.1

ZNF467 SSPOP

1.47e-03743527q36.1
Cytoband21q22.3

UMODL1 LINC01547

4.32e-0312835221q22.3
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF1 MEGF10 STAB1

5.89e-06272431253
GeneFamilySulfatases

ARSH ARSA

2.55e-0418242410
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF467 ZNF446 ZNF689 ZNF697

1.39e-0271824428
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 NOTCH3

1.21e-0616353M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 NOTCH3

1.21e-0616353MM1296
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

TIE1 NOTCH1 NOTCH3 STAB1

3.11e-05135354M5825
CoexpressionKOMMAGANI_TP63_GAMMA_TARGETS

JAG2 NOTCH3

6.20e-059352M9630
CoexpressionFAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON

JAG2 SHISA9 CSMD1 LTBP4

6.97e-05166354M39026
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

TGFB1I1 SCARF1 TIE1 NOTCH1 NOTCH3

1.17e-04365355M39018
CoexpressionGSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP

SCARF1 MEGF8 TESK1 LRP8

1.40e-04199354M9705
CoexpressionGSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_UP

FLCN ZNF467 LTBP4 ITGB6

1.43e-04200354M3776
CoexpressionGSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN

TRAPPC14 MEGF8 ZNF467 LRP8

1.43e-04200354M7162
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM

SCARF1 JAG2 ZNF467 TIE1

1.96e-04217354M16407
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM

SCARF1 JAG2 ZNF467 TIE1

2.36e-04228354MM1014
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 MEGF11 NOTCH1 STAB1

7.68e-09190356bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 MEGF11 NOTCH1 STAB1

7.68e-09190356d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 MEGF11 NOTCH1 STAB1

7.68e-0919035638a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 MEGF6 TIE1 NOTCH1 STAB1

2.03e-0716835506dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 MEGF6 TIE1 NOTCH1 STAB1

2.03e-071683551002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.27e-07185355dec60254204014083ff3b4aec0cc75410950a486
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.27e-07185355201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.27e-07185355334f006c3ef33338ff8d649309d3f448733a3a99
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 MEGF6 TIE1 NOTCH1 STAB1

3.27e-07185355a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 JAG2 MEGF6 TIE1 LTBP4

3.45e-07187355e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 ZNF467 TIE1 SSPOP NOTCH1

3.54e-07188355524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 ZNF467 TIE1 SSPOP NOTCH1

3.54e-07188355d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.83e-0719135579b399496bd7322a1d53c43378f48695fd09a5d9
ToppCellfacs-Trachea-24m-Endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.83e-071913559c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 JAG2 MEGF6 TIE1 LTBP4

3.83e-07191355b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.83e-071913551b1e943709d0c3283a980c7c965ef1f110506a29
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.93e-071923550986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SCARF1 JAG2 TIE1 NOTCH1

3.93e-07192355777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SCARF1 JAG2 TIE1 NOTCH1

3.93e-0719235560a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.93e-071923558f20d3511dcb44445592b17d005a53da0052ae56
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SCARF1 JAG2 TIE1 NOTCH1

3.93e-071923550f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1 STAB1

3.93e-07192355b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 LTBP4 NOTCH1 STAB1

3.93e-07192355d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 LTBP4 NOTCH1 STAB1

3.93e-071923552bfac6b3956265205ca47d06888851ed68b65999
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 LTBP4 NOTCH1 STAB1

4.14e-07194355c8b9551b93a5aed62154b487db90130604a6125c
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SCARF1 TIE1 LTBP4 STAB1

4.24e-07195355f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SCARF1 TIE1 LTBP4 STAB1

4.24e-07195355ea1b00805391dca8be0883b635768b296369919a
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 LTBP4 NOTCH1 STAB1

4.24e-0719535512ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SCARF1 TIE1 LTBP4 STAB1

4.24e-0719535585df110f753f58ab017018c54ee454edb4428e29
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

JAG2 CSMD1 TIE1 LTBP4 ZNF446

4.81e-07200355b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CSMD1 MEGF10 NOTCH3 ZNF697

5.15e-061463542ac9b487a7991fdc15444aeb93533030e09825bb
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

SHISA9 MEGF6 TENM3 NOTCH3

5.58e-06149354dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9

SCARF1 JAG2 NOTCH1 NOTCH3

7.59e-0616135452239a887799362256ecd7e740b716b88ed59a62
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TGFB1I1 CSMD1 MEGF6 NOTCH3

7.96e-0616335451dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCARF1 MEGF6 TIE1 MUC2

9.40e-06170354af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellT_cells-CD56_bright_CD16-_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

JAG2 ARSH TIE1 DSG1

9.84e-06172354980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCARF1 MEGF6 TIE1 MUC2

9.84e-061723549a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRB2 JAG2 ZNF467 TIE1

1.13e-05178354c30d3390fc4a7856f50ba8ff6694c0333165ddde
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF6 TIE1 LTBP4 STAB1

1.15e-05179354a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 TIE1 STAB1

1.18e-051803545861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEGF6 TIE1 LTBP4 STAB1

1.26e-051833546f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 NOTCH1 STAB1

1.28e-05184354fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 NOTCH1 STAB1

1.28e-051843541d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 NOTCH1 STAB1

1.28e-05184354ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 NOTCH1 STAB1

1.28e-0518435476caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 NOTCH1 STAB1

1.28e-051843541fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 NOTCH1 STAB1

1.28e-051843542467207aaea307873ab286f89cfc7668a227a694
ToppCelldroplet-Heart-4Chambers-21m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 MEGF6 TIE1 NOTCH1

1.28e-05184354f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 SCARF1 TIE1 LTBP4

1.34e-051863545d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 TIE1 STAB1

1.37e-0518735403de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH3 STAB1

1.40e-05188354da862ea3c74f42d0dbae38b09211a45c593d477e
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 JAG2 LTBP4 NOTCH3

1.40e-05188354ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH3 STAB1

1.40e-05188354b82a7667ef74a05e8bc744f6c090a7cc7b8efe32
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH3 STAB1

1.40e-0518835419672d284fe89c9c3c7697514ca1f659329c34f4
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 NOTCH1 STAB1

1.43e-05189354e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 JAG2 TIE1 LTBP4

1.43e-051893542ce330d8078833c05775c481e73770f9ee4a5c88
ToppCellfacs-Trachea-nan-18m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 NOTCH1 STAB1

1.43e-051893545ced78f4b5c276b1bab24df807c00cf5ac8ed3d4
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JAG2 CSMD1 TIE1 LTBP4

1.43e-05189354b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 NOTCH1 STAB1

1.43e-05189354ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 JAG2 TIE1 LTBP4

1.43e-05189354473c87036e04a058b4a5138438b7ba7e1e766799
ToppCellfacs-Trachea-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 NOTCH1 STAB1

1.43e-05189354f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCellfacs-Trachea-nan-18m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 NOTCH1 STAB1

1.43e-051893542105d8b011b93a460237e00bc029efd7762dc8d5
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|(2)_5-FU / Stress and Cell class

SCARF1 TIE1 NOTCH1 STAB1

1.43e-051893540f169b17bb26a812a5b0dcd6e29a3ca8415fd197
ToppCellfacs-Trachea-nan-18m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 TIE1 NOTCH1 STAB1

1.43e-05189354100eda87ac9c38dddcfa58408b057867a1738acb
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 NOTCH1 STAB1

1.43e-0518935428b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 LTBP4 STAB1

1.46e-05190354a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 TIE1 STAB1

1.46e-051903549a2244c3973aee7270646bf00db7727edb9decc5
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 TIE1 LTBP4 NOTCH1

1.46e-05190354d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 TIE1 NOTCH1

1.46e-05190354632d5dc11765053366d61f0a0c7916111cea4f50
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JAG2 CSMD1 TIE1 LTBP4

1.46e-05190354aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 LTBP4 STAB1

1.46e-051903540bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SHISA9 AHI1-DT ITGB6 MEGF11

1.46e-051903543fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 TIE1 LTBP4 STAB1

1.46e-0519035426e2237f65cb43723c5da853831b40df2982d6e4
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 TIE1 LTBP4 NOTCH1

1.49e-05191354b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SHISA9 AHI1-DT ITGB6 MEGF11

1.49e-051913549032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEGF6 TIE1 LTBP4 NOTCH1

1.49e-05191354d162917816dd2e4767c97447c1cddae9397713ab
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JAG2 CSMD1 TIE1 LTBP4

1.49e-051913544b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SHISA9 AHI1-DT ITGB6 MEGF11

1.49e-051913545717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellP03-Endothelial-large_vessel_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEGF6 TIE1 LTBP4 NOTCH1

1.49e-05191354b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 TIE1 STAB1

1.49e-05191354e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 MEGF6 TIE1 LTBP4

1.52e-051923541990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TGFB1I1 CSMD1 MEGF6 NOTCH3

1.52e-05192354a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 TIE1 LTBP4 NOTCH1

1.52e-05192354285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 MEGF6 TIE1 LTBP4

1.52e-05192354845cc9c18b4436b07dd3ce7980052683937546d2
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH1 STAB1

1.52e-051923545890076929598e88fe9d59a4e4e858b446746ce9
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 JAG2 TIE1 NOTCH1

1.52e-051923545012cc3ec0766f06af447463413422b484446c43
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|(1)_Control_(PBS) / Stress and Cell class

SCARF1 TIE1 NOTCH1 STAB1

1.52e-05192354e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 MEGF6 TIE1 LTBP4

1.52e-05192354c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCell(4)_Endothelial_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SCARF1 TIE1 NOTCH1 STAB1

1.55e-05193354ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH1 STAB1

1.55e-05193354826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellfacs-MAT-Fat-24m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1

1.55e-05193354ba9a47e2dc01efa6d2a99b1631d4951fac2648d4
ToppCellfacs-MAT-Fat-24m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1

1.55e-05193354724bb613fa434add5b1c5586b629328f819fbdfe
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH1 STAB1

1.55e-051933544a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TGFB1I1 CSMD1 MEGF6 NOTCH3

1.55e-05193354360079cbaa18b74e4a48c5de40844faca076e1a6
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH1 STAB1

1.55e-0519335487d3a577d37fb0cb4b6313c596310de452bc3872
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 TIE1 LTBP4 NOTCH1

1.55e-0519335458c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH1 STAB1

1.55e-05193354d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCellfacs-MAT-Fat-24m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 TIE1 NOTCH1

1.55e-05193354737e540c72a3cfe8dbd4c0f139f7d729a166793a
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIE1 LTBP4 NOTCH1 STAB1

1.55e-05193354d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 TIE1 STAB1

1.58e-05194354efd5efed060edb7f24d59600981bb60ec28ac2ef
DiseaseGlioblastoma

JAG2 LTBP4 NOTCH1 NOTCH3

1.84e-0679334C0017636
DiseaseGiant Cell Glioblastoma

JAG2 LTBP4 NOTCH1 NOTCH3

2.35e-0684334C0334588
DiseaseCarcinoma, Pancreatic Ductal

JAG2 NOTCH1 NOTCH3

2.54e-0624333C0887833
DiseaseGlioblastoma Multiforme

JAG2 LTBP4 NOTCH1 NOTCH3

7.13e-06111334C1621958
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH3

2.54e-057332DOID:3620 (implicated_via_orthology)
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH3

2.54e-057332DOID:299 (implicated_via_orthology)
Diseasepostburn hypertrophic scarring severity measurement

CSMD1 DSG1

5.43e-0510332EFO_0007747
DiseaseConnective Tissue Diseases

FLCN NOTCH1

9.39e-0513332C0009782
Diseaseserum IgG glycosylation measurement

FLCN CSMD1 TENM3 UMODL1 MEGF10

2.70e-04523335EFO_0005193
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH3

3.88e-0426332DOID:1319 (implicated_via_orthology)
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

5.17e-0430332DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

5.89e-0432332DOID:10155 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MEGF11 MEGF10

1.32e-0348332DOID:423 (implicated_via_orthology)
Diseaseresponse to cisplatin, platinum measurement

CSMD1 TENM3

1.61e-0353332EFO_0010154, GO_0072718
Diseaseperiodontitis

SHISA9 CSMD1 ITGB6

1.97e-03223333EFO_0000649

Protein segments in the cluster

PeptideGeneStartEntry
FTCSCEGGAPDFPVE

UMODL1

921

Q5DID0
CGFAQPGCSCPGEAG

ADGRB2

216

O60241
RGCCRGCASFSPFPA

LINC01547

116

P58512
PCCGTFPFCGCDKED

ARSH

541

Q5FYA8
DFPAPFCRAEGACGG

CSMD1

196

Q96PZ7
TAFFQEEGPCGACPG

AHI1-DT

146

P0C7V0
RCPPGYTGAFCEDLC

MEGF10

211

Q96KG7
DGSCECAPGFRGPLC

MEGF11

591

A6BM72
YSCTCPPGFVGERCE

NOTCH1

1251

P46531
CEVCPGREGPIFFGD

FLCN

131

Q8NFG4
FRCECAPGFAGPDCR

JAG2

811

Q9Y219
PDHPSCSGRGDCYCG

ITGB6

506

P18564
GFAPVDGCGCPDHTF

MUC2

691

Q02817
FSCSCLPGFAGPRCA

NOTCH3

871

Q9UM47
DCGHGVCSGPPDFTC

MEGF8

1121

Q7Z7M0
CFPPATPCDGGCDQG

ARSA

161

P15289
CDCGGAPRSAAGFEP

DSG1

571

Q02413
DGPCPTGFERVNGSC

LTBP4

341

Q8N2S1
SPGSFRCVCGPGFRA

LTBP4

606

Q8N2S1
PGSFRCVCPAGFRGS

LTBP4

691

Q8N2S1
CRCPPGFTGDFCETE

CELSR3

1421

Q9NYQ7
CADPACGPREFRCGG

LRP8

201

Q14114
ACRCPPGFTGSGCEQ

MEGF6

1146

O75095
CEPATGTCRCGPGFY

MEGF6

1356

O75095
FCERGCEPGSFGEGC

MEGF6

1416

O75095
CGPFEFRCGSGECTP

SSPOP

1566

A2VEC9
RIFFGPVSCPCCGTS

PRAMEF22

451

A3QJZ6
PPFNCSSGDFIFCCG

SHISA9

86

B4DS77
PCPTGTFGEDCGSTC

SCARF1

341

Q14162
GSFCRLPGTSGCFPC

TRAPPC14

291

Q8WVR3
DGECVCPPGFTGTRC

TIE1

241

P35590
GFEGDGFSCTPSNPC

STAB1

851

Q9NY15
GTCHCFPGFLGPDCS

TENM3

531

Q9P273
LPCPGCCLGPFSFGF

TESK1

566

Q15569
GPRSYPCEECGCSFS

ZNF446

391

Q9NWS9
CPDCGESFSPGAAFL

ZNF697

191

Q5TEC3
SGGPICPDCGCTFPD

ZNF689

146

Q96CS4
FCCVSCGEPFGDEGF

TGFB1I1

311

O43294
SGERSFFCPDCGRGF

ZNF467

426

Q7Z7K2