Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bone sialoprotein binding	ANXA2 ANXA2P2	8.01e-06	2	57	2	GO:0044730
GeneOntologyMolecularFunction	phospholipase A2 inhibitor activity	ANXA2 ANXA2P2	7.96e-05	5	57	2	GO:0019834
GeneOntologyMolecularFunction	dioxygenase activity	JMJD4 OGFOD3 UTY ALOX12B	1.77e-04	98	57	4	GO:0051213
GeneOntologyMolecularFunction	dipeptidyl-peptidase activity	DPP4 DPP6	5.19e-04	12	57	2	GO:0008239
GeneOntologyMolecularFunction	phospholipase inhibitor activity	ANXA2 ANXA2P2	6.12e-04	13	57	2	GO:0004859
GeneOntologyMolecularFunction	S100 protein binding	ANXA2 ANXA2P2	8.21e-04	15	57	2	GO:0044548
GeneOntologyBiologicalProcess	regulation of plasma membrane repair	MYH9 ANXA2 ANXA2P2	1.05e-06	8	56	3	GO:1905684
GeneOntologyBiologicalProcess	plasma membrane repair	MYH9 MYH10 ANXA2 ANXA2P2	2.13e-06	34	56	4	GO:0001778
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	7.24e-06	2	56	2	GO:1905597
GeneOntologyBiologicalProcess	positive regulation of receptor recycling	ANXA2 ANXA2P2 INPP5F	1.50e-05	18	56	3	GO:0001921
GeneOntologyBiologicalProcess	regulation of plasma membrane organization	MYH9 ANXA2 ANXA2P2	2.09e-05	20	56	3	GO:1903729
GeneOntologyBiologicalProcess	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	2.17e-05	3	56	2	GO:1905602
GeneOntologyBiologicalProcess	negative regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	2.17e-05	3	56	2	GO:0032804
GeneOntologyBiologicalProcess	actin filament bundle distribution	MYH9 MYH10	2.17e-05	3	56	2	GO:0070650
GeneOntologyBiologicalProcess	immunoglobulin mediated immune response	C5 IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-28 SVEP1	4.14e-05	235	56	6	GO:0016064
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2	4.33e-05	4	56	2	GO:1905581
GeneOntologyBiologicalProcess	negative regulation of receptor catabolic process	ANXA2 ANXA2P2	4.33e-05	4	56	2	GO:2000645
GeneOntologyBiologicalProcess	positive regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	4.33e-05	4	56	2	GO:0032385
GeneOntologyBiologicalProcess	positive regulation of intracellular sterol transport	ANXA2 ANXA2P2	4.33e-05	4	56	2	GO:0032382
GeneOntologyBiologicalProcess	B cell mediated immunity	C5 IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-28 SVEP1	5.10e-05	244	56	6	GO:0019724
GeneOntologyBiologicalProcess	response to wounding	MYH9 MYH10 ANXA2 ANXA2P2 C5 INPP5F ITGB4 STK24 SVEP1	6.50e-05	659	56	9	GO:0009611
GeneOntologyBiologicalProcess	positive regulation of plasma membrane repair	ANXA2 ANXA2P2	7.20e-05	5	56	2	GO:1905686
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	7.20e-05	5	56	2	GO:1905595
GeneOntologyBiologicalProcess	positive regulation of intracellular lipid transport	ANXA2 ANXA2P2	7.20e-05	5	56	2	GO:0032379
GeneOntologyBiologicalProcess	regulation of receptor recycling	ANXA2 ANXA2P2 INPP5F	8.07e-05	31	56	3	GO:0001919
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein receptor activity	ANXA2 ANXA2P2	1.08e-04	6	56	2	GO:1905599
GeneOntologyBiologicalProcess	intracellular cholesterol transport	VPS52 ANXA2 ANXA2P2	1.27e-04	36	56	3	GO:0032367
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	1.51e-04	7	56	2	GO:0032803
GeneOntologyBiologicalProcess	low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	1.51e-04	7	56	2	GO:0032802
GeneOntologyBiologicalProcess	low-density lipoprotein receptor particle metabolic process	ANXA2 ANXA2P2	1.51e-04	7	56	2	GO:0032799
GeneOntologyBiologicalProcess	intracellular sterol transport	VPS52 ANXA2 ANXA2P2	1.62e-04	39	56	3	GO:0032366
GeneOntologyBiologicalProcess	regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	2.01e-04	8	56	2	GO:1905600
GeneOntologyBiologicalProcess	positive regulation of receptor binding	ANXA2 ANXA2P2	2.01e-04	8	56	2	GO:1900122
GeneOntologyBiologicalProcess	lymphocyte mediated immunity	DPP4 C5 IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-28 SVEP1	2.04e-04	449	56	7	GO:0002449
GeneOntologyBiologicalProcess	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	DPP4 C5 IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-28 SVEP1	2.43e-04	462	56	7	GO:0002460
GeneOntologyBiologicalProcess	receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	3.92e-04	11	56	2	GO:0090118
GeneOntologyBiologicalProcess	intracellular lipid transport	VPS52 ANXA2 ANXA2P2	4.03e-04	53	56	3	GO:0032365
GeneOntologyBiologicalProcess	receptor recycling	ANXA2 ANXA2P2 INPP5F	4.50e-04	55	56	3	GO:0001881
GeneOntologyBiologicalProcess	positive regulation of lipoprotein particle clearance	ANXA2 ANXA2P2	4.70e-04	12	56	2	GO:0010986
GeneOntologyBiologicalProcess	regulation of intracellular sterol transport	ANXA2 ANXA2P2	4.70e-04	12	56	2	GO:0032380
GeneOntologyBiologicalProcess	regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	4.70e-04	12	56	2	GO:0032383
GeneOntologyBiologicalProcess	regulation of intracellular lipid transport	ANXA2 ANXA2P2	5.54e-04	13	56	2	GO:0032377
GeneOntologyBiologicalProcess	regulation of receptor catabolic process	ANXA2 ANXA2P2	6.45e-04	14	56	2	GO:2000644
GeneOntologyBiologicalProcess	regulation of alcohol biosynthetic process	MYH9 LPCAT3 ADCYAP1R1	7.35e-04	65	56	3	GO:1902930
GeneOntologyBiologicalProcess	cell-matrix adhesion	MYH9 ANXA2 ANXA2P2 ITGB4 SVEP1	8.20e-04	270	56	5	GO:0007160
GeneOntologyBiologicalProcess	positive regulation of inositol phosphate biosynthetic process	MYH9 ADCYAP1R1	8.48e-04	16	56	2	GO:0060732
GeneOntologyBiologicalProcess	leukocyte mediated immunity	DPP4 C5 IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-28 SVEP1	9.05e-04	576	56	7	GO:0002443
GeneOntologyBiologicalProcess	negative regulation of cell migration	DPP4 MYH9 ARID4A STK26 C5 STK24	9.33e-04	419	56	6	GO:0030336
GeneOntologyBiologicalProcess	protein processing	DPP4 MYH9 DYNC2H1 ANXA2 PCSK4	1.04e-03	285	56	5	GO:0016485
GeneOntologyBiologicalProcess	regulation of inositol phosphate biosynthetic process	MYH9 ADCYAP1R1	1.08e-03	18	56	2	GO:0010919
GeneOntologyBiologicalProcess	negative regulation of cell motility	DPP4 MYH9 ARID4A STK26 C5 STK24	1.13e-03	435	56	6	GO:2000146
GeneOntologyCellularComponent	basement membrane	FRAS1 ANXA2 ANXA2P2 USH2A ITGB4	1.88e-05	122	56	5	GO:0005604
GeneOntologyCellularComponent	myosin II filament	MYH9 MYH10	2.11e-05	3	56	2	GO:0097513
GeneOntologyCellularComponent	AnxA2-p11 complex	ANXA2 ANXA2P2	2.11e-05	3	56	2	GO:1990665
GeneOntologyCellularComponent	PCSK9-AnxA2 complex	ANXA2 ANXA2P2	2.11e-05	3	56	2	GO:1990667
GeneOntologyCellularComponent	myelin sheath adaxonal region	ANXA2 ANXA2P2	1.47e-04	7	56	2	GO:0035749
GeneOntologyCellularComponent	contractile actin filament bundle	MYH9 MYH10 ANXA2 ANXA2P2	1.94e-04	107	56	4	GO:0097517
GeneOntologyCellularComponent	stress fiber	MYH9 MYH10 ANXA2 ANXA2P2	1.94e-04	107	56	4	GO:0001725
GeneOntologyCellularComponent	actomyosin	MYH9 MYH10 ANXA2 ANXA2P2	2.73e-04	117	56	4	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	MYH9 MYH10 ANXA2 ANXA2P2	2.83e-04	118	56	4	GO:0032432
GeneOntologyCellularComponent	cell leading edge	DPP4 MYH9 MYH10 ANXA2 ANXA2P2 USH2A ITGB4	3.62e-04	500	56	7	GO:0031252
GeneOntologyCellularComponent	pinosome	ANXA2 ANXA2P2	3.82e-04	11	56	2	GO:0044352
GeneOntologyCellularComponent	macropinosome	ANXA2 ANXA2P2	3.82e-04	11	56	2	GO:0044354
GeneOntologyCellularComponent	FAR/SIN/STRIPAK complex	STK26 STK24	9.34e-04	17	56	2	GO:0090443
GeneOntologyCellularComponent	Schmidt-Lanterman incisure	ANXA2 ANXA2P2	9.34e-04	17	56	2	GO:0043220
GeneOntologyCellularComponent	immunoglobulin complex	IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-28	1.02e-03	166	56	4	GO:0019814
GeneOntologyCellularComponent	compact myelin	ANXA2 ANXA2P2	1.43e-03	21	56	2	GO:0043218
GeneOntologyCellularComponent	myosin filament	MYH9 MYH10	2.03e-03	25	56	2	GO:0032982
GeneOntologyCellularComponent	myosin II complex	MYH9 MYH10	2.55e-03	28	56	2	GO:0016460
GeneOntologyCellularComponent	cell cortex	MYH9 MYH10 ANXA2 ANXA2P2 ITGB4	3.12e-03	371	56	5	GO:0005938
Domain	-	DPP4 DPP6	1.09e-04	6	51	2	2.140.10.30
Domain	DPPIV_N	DPP4 DPP6	1.09e-04	6	51	2	PF00930
Domain	Peptidase_S9B_N	DPP4 DPP6	1.09e-04	6	51	2	IPR002469
Domain	Calx_beta	FRAS1 ITGB4	2.03e-04	8	51	2	SM00237
Domain	Calx_beta	FRAS1 ITGB4	2.60e-04	9	51	2	IPR003644
Domain	Calx-beta	FRAS1 ITGB4	2.60e-04	9	51	2	PF03160
Domain	Peptidase_S9	DPP4 DPP6	3.96e-04	11	51	2	PF00326
Domain	Peptidase_S9	DPP4 DPP6	3.96e-04	11	51	2	IPR001375
Domain	Myosin_N	MYH9 MYH10	7.50e-04	15	51	2	PF02736
Domain	Myosin_N	MYH9 MYH10	7.50e-04	15	51	2	IPR004009
Domain	Myosin_tail_1	MYH9 MYH10	1.09e-03	18	51	2	PF01576
Domain	Myosin_tail	MYH9 MYH10	1.09e-03	18	51	2	IPR002928
Domain	Furin_repeat	FRAS1 PCSK4	1.09e-03	18	51	2	IPR006212
Domain	FU	FRAS1 PCSK4	1.09e-03	18	51	2	SM00261
Domain	Myosin-like_IQ_dom	MYH9 MYH10	1.21e-03	19	51	2	IPR027401
Domain	-	MYH9 MYH10	1.21e-03	19	51	2	4.10.270.10
Domain	JmjC	JMJD4 UTY	1.94e-03	24	51	2	PF02373
Domain	JMJC	JMJD4 UTY	3.44e-03	32	51	2	PS51184
Domain	JmjC_dom	JMJD4 UTY	3.44e-03	32	51	2	IPR003347
Domain	JmjC	JMJD4 UTY	3.66e-03	33	51	2	SM00558
Domain	Myosin_head_motor_dom	MYH9 MYH10	4.83e-03	38	51	2	IPR001609
Domain	MYOSIN_MOTOR	MYH9 MYH10	4.83e-03	38	51	2	PS51456
Domain	Myosin_head	MYH9 MYH10	4.83e-03	38	51	2	PF00063
Domain	MYSc	MYH9 MYH10	4.83e-03	38	51	2	SM00242
Domain	EGF_1	USH2A ITGB4 TENM2 SVEP1	5.13e-03	255	51	4	PS00022
Pathway	REACTOME_COMPLEMENT_CASCADE	C5 IGHV4-61 IGHV4-31 IGHV4-28	1.00e-04	84	41	4	MM14653
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGHV4-61 IGHV4-31 IGHV4-28	1.40e-04	35	41	3	MM17219
Pathway	REACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION	IGHV4-61 IGHV4-31 IGHV4-28	1.94e-04	39	41	3	MM17212
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGHV4-61 IGHV4-31 IGHV4-28	2.98e-04	45	41	3	MM14912
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	MYH9 IGHV4-61 IGHV4-31 IGHV4-28	3.26e-04	114	41	4	MM14814
Pathway	REACTOME_FCGR_ACTIVATION	IGHV4-61 IGHV4-31 IGHV4-28	3.61e-04	48	41	3	MM17214
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGHV4-61 IGHV4-31 IGHV4-28	4.84e-04	53	41	3	MM15716
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGHV4-61 IGHV4-31 IGHV4-28	5.11e-04	54	41	3	MM14655
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGHV4-61 IGHV4-31 IGHV4-28	5.69e-04	56	41	3	MM14815
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGHV4-61 IGHV4-31 IGHV4-28	6.31e-04	58	41	3	MM14914
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGHV4-61 IGHV4-31 IGHV4-28	6.96e-04	60	41	3	MM14913
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGHV4-61 IGHV4-31 IGHV4-28	6.96e-04	60	41	3	MM14872
Pathway	REACTOME_DISSOLUTION_OF_FIBRIN_CLOT	ANXA2 ANXA2P2	8.46e-04	15	41	2	MM15450
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	MYH9 MYH10	1.37e-03	19	41	2	M27493
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_CIT	MYH9 MYH10	1.37e-03	19	41	2	M27489
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	MYH9 MYH10	1.52e-03	20	41	2	M18415
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PAKS	MYH9 MYH10	1.67e-03	21	41	2	M27494
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PAKS	MYH9 MYH10	2.01e-03	23	41	2	MM15222
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	MYH9 MYH10	2.19e-03	24	41	2	M2243
Pubmed	Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.	MYH9 MYH10 ITGB4	4.39e-08	5	58	3	25006807
Pubmed	Cloning, sequencing and expression of the rearranged MOPC 315 VH gene segment.	IGHV4-61 IGHV4-31 IGHV4-28	1.53e-07	7	58	3	2497341
Pubmed	The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.	IGHV4-61 IGHV4-31 IGHV4-28	1.53e-07	7	58	3	3937730
Pubmed	Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.	IGHV4-61 IGHV4-31 IGHV4-28	1.53e-07	7	58	3	268248
Pubmed	The structure of the expressible VH gene from a hybridoma producing monoclonal antibodies against porcine transferrin.	IGHV4-61 IGHV4-31 IGHV4-28	1.53e-07	7	58	3	2587273
Pubmed	Amino acid sequence of the precursor region of MOPC-315 mouse immunoglobulin heavy chain.	IGHV4-61 IGHV4-31 IGHV4-28	1.53e-07	7	58	3	414225
Pubmed	Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity.	IGHV4-61 IGHV4-31 IGHV4-28	1.53e-07	7	58	3	4524622
Pubmed	A new germline VH36-60 gene is used in the neonatal primary and adult memory response to (T,G)-A--L.	IGHV4-61 IGHV4-31 IGHV4-28	1.53e-07	7	58	3	1683681
Pubmed	STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development.	STK3 STK26 STK24	3.67e-07	9	58	3	34518307
Pubmed	Structure and function of immunoglobulin genes and precursors.	IGHV4-61 IGHV4-31 IGHV4-28	5.24e-07	10	58	3	428562
Pubmed	Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression.	MYH9 MYH10	2.73e-06	2	58	2	21792479
Pubmed	Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics.	MYH9 MYH10	2.73e-06	2	58	2	22328520
Pubmed	A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.	ANXA2 ANXA2P2	2.73e-06	2	58	2	21486955
Pubmed	Nonmuscle myosin II-B is required for normal development of the mouse heart.	MYH9 MYH10	2.73e-06	2	58	2	9356462
Pubmed	Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization.	MYH9 MYH10	2.73e-06	2	58	2	25185263
Pubmed	Dorsal root ganglion neurons react to semaphorin 3A application through a biphasic response that requires multiple myosin II isoforms.	MYH9 MYH10	2.73e-06	2	58	2	19109430
Pubmed	Non-Muscle Myosin II Isoforms Have Different Functions in Matrix Rearrangement by MDA-MB-231 Cells.	MYH9 MYH10	2.73e-06	2	58	2	26136073
Pubmed	Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.	ANXA2 ANXA2P2	2.73e-06	2	58	2	21737841
Pubmed	Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.	ANXA2 ANXA2P2	2.73e-06	2	58	2	19536308
Pubmed	Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration.	MYH9 MYH10	2.73e-06	2	58	2	17020881
Pubmed	Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.	ANXA2 ANXA2P2	2.73e-06	2	58	2	23148505
Pubmed	Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.	ANXA2 ANXA2P2	2.73e-06	2	58	2	19580511
Pubmed	Myosin II activity regulates neurite outgrowth and guidance in response to chondroitin sulfate proteoglycans.	MYH9 MYH10	2.73e-06	2	58	2	22191382
Pubmed	Myosin II isoforms play distinct roles in adherens junction biogenesis.	MYH9 MYH10	2.73e-06	2	58	2	31486768
Pubmed	Differential expression and functions of cortical myosin IIA and IIB isotypes during meiotic maturation, fertilization, and mitosis in mouse oocytes and embryos.	MYH9 MYH10	2.73e-06	2	58	2	9725909
Pubmed	ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.	ANXA2 ANXA2P2	2.73e-06	2	58	2	38290972
Pubmed	The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells.	MYH9 MYH10	2.73e-06	2	58	2	33415745
Pubmed	Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain.	MYH9 MYH10	2.73e-06	2	58	2	23128239
Pubmed	The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.	ANXA2 ANXA2P2	2.73e-06	2	58	2	3013423
Pubmed	Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.	ANXA2 ANXA2P2	2.73e-06	2	58	2	35064931
Pubmed	Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.	ANXA2 ANXA2P2	2.73e-06	2	58	2	28130864
Pubmed	Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.	ANXA2 ANXA2P2	2.73e-06	2	58	2	36739096
Pubmed	Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.	ANXA2 ANXA2P2	2.73e-06	2	58	2	17549680
Pubmed	Differential localization of myosin-II isozymes in human cultured cells and blood cells.	MYH9 MYH10	2.73e-06	2	58	2	7699007
Pubmed	Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.	ANXA2 ANXA2P2	2.73e-06	2	58	2	22517898
Pubmed	Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.	ANXA2 ANXA2P2	2.73e-06	2	58	2	39384746
Pubmed	Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.	ANXA2 ANXA2P2	2.73e-06	2	58	2	30462534
Pubmed	Conditional Myh9 and Myh10 inactivation in adult mouse renal epithelium results in progressive kidney disease.	MYH9 MYH10	2.73e-06	2	58	2	33001861
Pubmed	Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.	ANXA2 ANXA2P2	2.73e-06	2	58	2	20826156
Pubmed	Mutations in non-muscle myosin 2A disrupt the actomyosin cytoskeleton in Sertoli cells and cause male infertility.	MYH9 MYH10	2.73e-06	2	58	2	33188738
Pubmed	Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.	ANXA2 ANXA2P2	2.73e-06	2	58	2	27468426
Pubmed	Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.	ANXA2 ANXA2P2	2.73e-06	2	58	2	38092984
Pubmed	Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.	ANXA2 ANXA2P2	2.73e-06	2	58	2	21572519
Pubmed	Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.	ANXA2 ANXA2P2	2.73e-06	2	58	2	19841537
Pubmed	Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.	ANXA2 ANXA2P2	2.73e-06	2	58	2	21788340
Pubmed	The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.	ANXA2 ANXA2P2	2.73e-06	2	58	2	27371724
Pubmed	Distinct roles for non-muscle myosin II isoforms in mouse hepatic stellate cells.	MYH9 MYH10	2.73e-06	2	58	2	20932596
Pubmed	Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.	ANXA2 ANXA2P2	2.73e-06	2	58	2	27389701
Pubmed	The C-terminal tail region of nonmuscle myosin II directs isoform-specific distribution in migrating cells.	MYH9 MYH10	2.73e-06	2	58	2	18843042
Pubmed	Nonmuscle myosin IIA and IIB differentially contribute to intrinsic and directed migration of human embryonic lung fibroblasts.	MYH9 MYH10	2.73e-06	2	58	2	29486156
Pubmed	Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.	ANXA2 ANXA2P2	2.73e-06	2	58	2	31817350
Pubmed	Redistribution of insoluble interphotoreceptor matrix components during photoreceptor differentiation in the mouse retina.	MYH9 MYH10	2.73e-06	2	58	2	8089273
Pubmed	ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.	ANXA2 ANXA2P2	2.73e-06	2	58	2	37832154
Pubmed	Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.	ANXA2 ANXA2P2	2.73e-06	2	58	2	17360942
Pubmed	Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.	ANXA2 ANXA2P2	2.73e-06	2	58	2	19587120
Pubmed	Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes.	MYH9 MYH10	2.73e-06	2	58	2	1860190
Pubmed	Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.	ANXA2 ANXA2P2	2.73e-06	2	58	2	30902828
Pubmed	Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.	ANXA2 ANXA2P2	2.73e-06	2	58	2	19022301
Pubmed	Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.	ANXA2 ANXA2P2	2.73e-06	2	58	2	24742684
Pubmed	Different contributions of nonmuscle myosin IIA and IIB to the organization of stress fiber subtypes in fibroblasts.	MYH9 MYH10	2.73e-06	2	58	2	29467250
Pubmed	Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.	ANXA2 ANXA2P2	2.73e-06	2	58	2	32687500
Pubmed	Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.	ANXA2 ANXA2P2	2.73e-06	2	58	2	22453828
Pubmed	Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.	ANXA2 ANXA2P2	2.73e-06	2	58	2	38253182
Pubmed	Non-muscle myosin IIB is essential for cytokinesis during male meiotic cell divisions.	MYH9 MYH10	2.73e-06	2	58	2	22820068
Pubmed	Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis.	MYH9 MYH10	2.73e-06	2	58	2	22393000
Pubmed	Nonmuscle myosin IIA and IIB differentially modulate migration and alter gene expression in primary mouse tumorigenic cells.	MYH9 MYH10	2.73e-06	2	58	2	30995168
Pubmed	Agents that bind annexin A2 suppress ocular neovascularization.	ANXA2 ANXA2P2	2.73e-06	2	58	2	20607799
Pubmed	STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.	STK26 STK24	2.73e-06	2	58	2	37490000
Pubmed	Expression of four myosin heavy chain isoforms with development in mouse uterus.	MYH9 MYH10	2.73e-06	2	58	2	8402956
Pubmed	Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes.	MYH9 MYH10	2.73e-06	2	58	2	27737892
Pubmed	A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.	ANXA2 ANXA2P2	2.73e-06	2	58	2	31253864
Pubmed	Concerted actions of distinct nonmuscle myosin II isoforms drive intracellular membrane remodeling in live animals.	MYH9 MYH10	2.73e-06	2	58	2	28600434
Pubmed	Single quantum dot tracking reveals that an individual multivalent HIV-1 Tat protein transduction domain can activate machinery for lateral transport and endocytosis.	MYH9 MYH10	2.73e-06	2	58	2	23732912
Pubmed	Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.	ANXA2 ANXA2P2	2.73e-06	2	58	2	22185818
Pubmed	Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.	ANXA2 ANXA2P2	2.73e-06	2	58	2	19628708
Pubmed	Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.	ANXA2 ANXA2P2	2.73e-06	2	58	2	15654879
Pubmed	Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis.	MYH9 MYH10	2.73e-06	2	58	2	12893741
Pubmed	Dynamic assembly properties of nonmuscle myosin II isoforms revealed by combination of fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy.	MYH9 MYH10	2.73e-06	2	58	2	21106542
Pubmed	Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.	ANXA2 ANXA2P2	2.73e-06	2	58	2	20847146
Pubmed	Conditional expression of a truncated fragment of nonmuscle myosin II-A alters cell shape but not cytokinesis in HeLa cells.	MYH9 MYH10	2.73e-06	2	58	2	11029059
Pubmed	Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: relevance for MYH9-related disease.	MYH9 MYH10	2.73e-06	2	58	2	16596254
Pubmed	Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.	IGHV4-61 IGHV4-31 IGHV4-28	6.63e-06	22	58	3	2499654
Pubmed	STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.	ANXA2 ANXA2P2	8.19e-06	3	58	2	35098646
Pubmed	Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.	ANXA2 ANXA2P2	8.19e-06	3	58	2	36367512
Pubmed	Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction.	ANXA2 ANXA2P2	8.19e-06	3	58	2	26416603
Pubmed	Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.	ANXA2 ANXA2P2	8.19e-06	3	58	2	23792445
Pubmed	The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.	ANXA2 ANXA2P2	8.19e-06	3	58	2	35413401
Pubmed	Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.	ANXA2 ANXA2P2	8.19e-06	3	58	2	28694388
Pubmed	High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.	ANXA2 ANXA2P2	8.19e-06	3	58	2	27470587
Pubmed	Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis.	MYH9 MYH10	8.19e-06	3	58	2	15774463
Pubmed	Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow.	ANXA2 ANXA2P2	8.19e-06	3	58	2	25139998
Pubmed	A three-protein signature and clinical outcome in esophageal squamous cell carcinoma.	MYH9 ANXA2	8.19e-06	3	58	2	25605255
Pubmed	Annexins--unique membrane binding proteins with diverse functions.	ANXA2 ANXA2P2	8.19e-06	3	58	2	15169834
Pubmed	Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.	ANXA2 ANXA2P2	8.19e-06	3	58	2	24808179
Pubmed	Structural mechanism of CCM3 heterodimerization with GCKIII kinases.	STK26 STK24	8.19e-06	3	58	2	23541896
Pubmed	Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells.	ANXA2 ANXA2P2	8.19e-06	3	58	2	25222280
Pubmed	The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.	ANXA2 ANXA2P2	8.19e-06	3	58	2	26963384
Pubmed	Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes.	ANXA2 ANXA2P2	8.19e-06	3	58	2	15064349
Pubmed	Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.	ANXA2 ANXA2P2	8.19e-06	3	58	2	28334824
Pubmed	Tenascin-c renders a proangiogenic phenotype in macrophage via annexin II.	ANXA2 ANXA2P2	8.19e-06	3	58	2	28857429
Cytoband	14q32.33	IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-30-2 IGHV4-28	1.07e-05	228	58	5	14q32.33
Cytoband	7p14	MRPS24 ADCYAP1R1	6.67e-04	30	58	2	7p14
GeneFamily	Immunoglobulin heavy locus at 14q32.33	IGHV4-61 IGHV4-31 IGHV4-30-4 IGHV4-30-2 IGHV4-28	7.85e-05	187	43	5	349
GeneFamily	CD molecules\|DASH family	DPP4 DPP6	1.15e-04	7	43	2	1205
GeneFamily	Myosin heavy chains	MYH9 MYH10	5.69e-04	15	43	2	1098
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STK26 STK24	1.02e-03	20	43	2	1371
GeneFamily	Olfactory receptors, family 9	OR9G1 OR9G9	1.35e-03	23	43	2	156
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Batf3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NDST3 DPP4 FRAS1 FEZF2 PCSK4	1.61e-06	157	56	5	921805932f7974d37aed547861d555b07f30aba6
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC6A7 GDA FRAS1 TENM2 ALOX12B	1.82e-06	161	56	5	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STK3 FRAS1 IGHV4-61 IGHV4-30-2 IGHV4-28	2.59e-06	173	56	5	09cd878c33534bd476d6a4880f5582076189da8c
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STK3 FRAS1 IGHV4-61 IGHV4-30-2 IGHV4-28	2.59e-06	173	56	5	62abaaaf48cabd1423f17fb27c33b75ea88867f4
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NDST3 FRAS1 FEZF2 ALOX12B	1.17e-05	111	56	4	1847dde68d349114286bc3317be6339666df4aa2
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 DYNC2H1 USH2A PCSK4	2.91e-05	140	56	4	5e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NDST3 SLC6A7 FEZF2 ALOX12B	3.25e-05	144	56	4	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC6A7 DPP4 FRAS1 FEZF2	6.20e-05	170	56	4	67415b098e8ba815b501e557192a9f2b10ee995a
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STK3 FRAS1 IGHV4-30-2 IGHV4-28	6.63e-05	173	56	4	b335ca2a247156eba821943b2b9fc9922230b409
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GDA FRAS1 FEZF2 ALOX12B	6.94e-05	175	56	4	21f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GDA FRAS1 FEZF2 ALOX12B	6.94e-05	175	56	4	ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NDST3 SLC6A7 GDA MYH9	7.09e-05	176	56	4	212e643c50c68462d4b016428ab30eeb7868ef40
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	DPP6 FRAS1 MYH10 SVEP1	7.25e-05	177	56	4	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	DPP6 FRAS1 MYH10 SVEP1	7.25e-05	177	56	4	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPP4 GDA FEZF2 ADCYAP1R1	7.74e-05	180	56	4	e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 MYH10 TENM2 SVEP1	7.90e-05	181	56	4	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DPP6 FRAS1 PAXBP1 C5	8.96e-05	187	56	4	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DPP6 FRAS1 MYH10 SVEP1	8.96e-05	187	56	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 MYH10 DYNC2H1 SVEP1	9.34e-05	189	56	4	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	STK3 DYNC2H1 UGGT2 SVEP1	9.73e-05	191	56	4	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	FRAS1 MYH10 TENM2 SVEP1	1.01e-04	193	56	4	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 MYH10 TENM2 SVEP1	1.03e-04	194	56	4	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	TNFSF14 SLC19A2 UGGT2 SVEP1	1.03e-04	194	56	4	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	DPP6 FRAS1 MYH10 SVEP1	1.05e-04	195	56	4	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	STK3 DYNC2H1 UGGT2 SVEP1	1.05e-04	195	56	4	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	Control-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	DPP4 MYH9 PCNX1 STK24	1.05e-04	195	56	4	6687e579582d7a239bee80846de0cf827a6f6a62
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 DLX3 ITGB4 TENM2	1.05e-04	195	56	4	6c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	DPP4 MYH9 PCNX1 STK24	1.07e-04	196	56	4	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	DPP4 MYH9 PCNX1 STK24	1.07e-04	196	56	4	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	MYH10 DYNC2H1 UTY SVEP1	1.10e-04	197	56	4	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	DPP6 FRAS1 MYH10 SVEP1	1.10e-04	197	56	4	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	(02)_MMP9/10+\|World / shred by cell type by condition	MYH9 ARID4A ITGB4 TENM2	1.14e-04	199	56	4	3f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCell	(5)_Fibroblast-G\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	DPP6 FRAS1 MYH10 SVEP1	1.14e-04	199	56	4	b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPP6 FRAS1 MYH10 SVEP1	1.14e-04	199	56	4	212e89d097753790061310373a1fafba773488b6
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Transitional_AT2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	NDST3 FEZF2 TMPRSS11E KLHL23	1.14e-04	199	56	4	cd581d7330b471431ef427f8a4f5be553f70e068
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPP6 FRAS1 MYH10 SVEP1	1.14e-04	199	56	4	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	medial-mesenchymal-Alveolar_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRAS1 MYH10 SLC19A2 SVEP1	1.16e-04	200	56	4	5c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCell	medial-mesenchymal-Alveolar_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRAS1 MYH10 SLC19A2 SVEP1	1.16e-04	200	56	4	c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCell	medial-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRAS1 MYH10 SLC19A2 SVEP1	1.16e-04	200	56	4	cc6062dac07916c29091fc6bee2b864d29e6525b
Disease	NF-kappa-B essential modulator measurement	STK3 STK24	9.13e-06	3	52	2	EFO_0010597
Disease	2-hydroxystearate measurement	STK3 STK24	1.09e-04	9	52	2	EFO_0021059
Disease	cerebral cavernous malformation (implicated_via_orthology)	STK26 STK24	1.66e-04	11	52	2	DOID:0060669 (implicated_via_orthology)
Disease	renal cell carcinoma (biomarker_via_orthology)	ANXA2 ANXA2P2	2.73e-04	14	52	2	DOID:4450 (biomarker_via_orthology)
Disease	diet measurement, colorectal cancer	DPP6 ST8SIA2	5.11e-04	19	52	2	EFO_0008111, MONDO_0005575
Disease	alcohol use disorder measurement	DPP4 DPP6 ARID4A TENM2	5.54e-04	214	52	4	EFO_0009458
Disease	coagulation factor V measurement	SLC19A2 DLX3	5.67e-04	20	52	2	EFO_0008087
Disease	FEV change measurement, response to zileuton	PCNX1 LMBRD1	8.90e-04	25	52	2	EFO_0005921, EFO_0007676
Disease	pseudotumor cerebri	OR9G1 OR9G9	9.64e-04	26	52	2	EFO_1001132
Disease	coronary artery disease	STK3 DPP6 ARID4A DYNC2H1 PKD2L1 C5 STK24 SVEP1	1.08e-03	1194	52	8	EFO_0001645
Disease	Hyalinosis, Segmental Glomerular	MYH9 MYH10	1.12e-03	28	52	2	C0086432
Disease	hyperthyroidism (biomarker_via_orthology)	ANXA2 ANXA2P2	1.12e-03	28	52	2	DOID:7998 (biomarker_via_orthology)
Disease	Cleft palate, cleft lip	STK3 MYH9 TENM2 STK24	1.48e-03	279	52	4	EFO_0003959, HP_0000175
Disease	pulse pressure measurement, diastolic blood pressure, systolic blood pressure, hypertension	STK3 STK24	1.75e-03	35	52	2	EFO_0000537, EFO_0005763, EFO_0006335, EFO_0006336

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASYNVKTAYRKYLYG	ARID4A	381	P29374
EYASKYLTARSTYYV	CXorf65	61	A6NEN9
YGKSLYYYIQQDTKG	ANXA2	311	P07355
YGKSLYYYIQQDTKG	ANXA2P2	311	A6NMY6
SPKSEYTYGASYRQY	DLX3	81	O60479
IIISAYYLYSGYKQE	NDST3	26	O95803
SVTLYYGSILYIYAL	OR9G1	246	Q8NH87
GYLKGYTLVEYETYK	RBM8A	111	Q9Y5S9
YGSFDYTSLLYLSNY	OGFOD3	236	Q6PK18
SYNRKDYSGEYTIYL	FRAS1	3596	Q86XX4
YIYYSGSTYYNPSLK	IGHV4-31	71	P0DP07
TVLYGYYTLYSVILF	LMBRD1	96	Q9NUN5
YIYHSGSTYYNPSLK	IGHV4-30-2	71	A0A087WSY4
YIYYSGSTYYNPSLK	IGHV4-30-4	71	P0DP06
YIYYSGSTNYNPSLK	IGHV4-61	71	A0A0C4DH41
LGYSVYRTVIEYYSA	NAA20	126	P61599
LTTYYVKGIIYYVTT	PCNX1	1696	Q96RV3
YYFNTGTLYRYTLLL	PCSK4	561	Q6UW60
LAGYYYTATGNYDIK	LPCAT3	126	Q6P1A2
TSDYLYYISNEYKGM	DPP4	411	P27487
YYSVSFSKEAKYYQL	DPP4	456	P27487
LKERYYSGLIYTYSG	MYH9	101	P35579
IYYSGSTYYNPSLKS	IGHV4-28	71	A0A0C4DH34
RSKYYTSYKDAYIGL	PAXBP1	606	Q9Y5B6
SVTLYYGSILYIYAL	OR9G9	246	P0C7N8
PIFAVTNYSYSYYEK	ITGB4	321	P16144
QDYYYLSVKALYTVG	ADCYAP1R1	146	P41586
YTYEYQGNASKLVYT	DYNC2H1	1651	Q8NCM8
YSYSKGTYLQSIEKY	KLHL23	516	Q8NBE8
SYYSLEDLNNKYLYI	C5	311	P01031
YITYWKEYIQAGYSS	JMJD4	161	Q9H9V9
KYVTEIITYYYPSDA	ALOX12B	511	O75342
VKNLYPSYKNYTSVY	GDA	251	Q9Y2T3
YQHSYTGYYVLSKIP	DPP6	211	P42658
SSSYMSSQKDYSYYL	POLI	611	Q9UNA4
YGIATATEIAYYSYI	SLC19A2	131	O60779
LLLLSNSAYYVAYYD	INPP5F	641	Q9Y2H2
YVYSPLGSAYKLQSY	SLC38A9	96	Q8NBW4
YVNYTKLYYVLESGE	DCAF15	386	Q66K64
KDRYYSGLIYTYSGL	MYH10	106	P35580
SGSLYYFNYLDSTAY	FEZF2	166	Q8TBJ5
YTPYLKFTQSYDYLT	RUNDC3A	201	Q59EK9
KYYFLVGYSETLLSY	MRPS24	131	Q96EL2
LDTDLLPYTKYSYYI	USH2A	1111	O75445
LPYTKYSYYIETTNV	USH2A	1116	O75445
YSKALSAYQRYYSLQ	UTY	106	O14607
TYEKGYCFVYYLSQL	RNPEPL1	441	Q9HAU8
TYKLYSYSYLGLGLM	ENTPD6	286	O75354
SPYVTKYYGSYLKDT	STK24	91	Q9Y6E0
QCDSSYVTKYYGSYL	STK26	76	Q9P289
YYDSLKYGYTSQASP	ST8SIA2	331	Q92186
KLGPYANTTKYTYDY	TENM2	2191	Q9NT68
IKGSNYTYLSTLYYE	SVEP1	2786	Q4LDE5
YSIVKYQPSEYGSYR	SLC6A7	516	Q99884
YNYYSTLSFTTDKLY	TMPRSS11E	51	Q9UL52
TLSKIYLSYYRSYLG	VPS52	291	Q8N1B4
YVVKYYGSYFKNTDL	STK3	81	Q13188
GALVVTKAGYYYIYS	TNFSF14	131	O43557
TKAGYYYIYSKVQLG	TNFSF14	136	O43557
LLTYGMTSSSAYYYT	PKD2L1	116	Q9P0L9
IYKQTESDYSYYNLI	UGGT2	76	Q9NYU1