Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide-glutamate-alpha-N-acetyltransferase activity

NAA11 NAA10

1.96e-052892GO:1990190
GeneOntologyMolecularFunctionpeptide-serine-alpha-N-acetyltransferase activity

NAA11 NAA10

5.88e-053892GO:1990189
GeneOntologyMolecularFunctioncyclic-nucleotide phosphodiesterase activity

PDE4A PDE5A CNP

2.32e-0427893GO:0004112
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 KIF1B KIF19 DYNC1LI1

2.70e-0470894GO:0003777
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 CECR2 KIF1B ATP6V0A4 KIF19 DYNC1LI1 CHD2 ATP2B4 NLRP3 VCP

4.02e-046148910GO:0140657
GeneOntologyMolecularFunctionpeptide alpha-N-acetyltransferase activity

NAA11 NAA10

5.41e-048892GO:0004596
GeneOntologyMolecularFunctioncyclic nucleotide binding

PDE4A PDE5A CNP

6.96e-0439893GO:0030551
GeneOntologyBiologicalProcesscyclic nucleotide catabolic process

PDE4A PDE5A CNP

2.46e-0514863GO:0009214
GeneOntologyBiologicalProcessregulation of T-helper 2 cell differentiation

BCL6 IL4R NLRP3

2.46e-0514863GO:0045628
GeneOntologyBiologicalProcesscyclic nucleotide metabolic process

NPPA PDE4A PDE5A CNP

3.68e-0545864GO:0009187
GeneOntologyBiologicalProcesscell cycle process

NCAPG LLGL2 PBRM1 MAP4 WEE1 RBL2 CECR2 NCAPD2 CKAP5 NAA10 DYNC1LI1 BCL6 CCDC57 ATP2B4 SPAG5 VCP NLRP5

8.06e-0514418617GO:0022402
GeneOntologyBiologicalProcessT-helper 2 cell differentiation

BCL6 IL4R NLRP3

8.82e-0521863GO:0045064
GeneOntologyBiologicalProcessregulation of T-helper cell differentiation

BCL6 IL4R IL23R NLRP3

9.40e-0557864GO:0045622
GeneOntologyBiologicalProcessmicrotubule-based process

DNAH3 LLGL2 MAP4 WEE1 KIF1B KIF19 CKAP5 DYNC1LI1 DYNC2I1 CCDC57 ATP2B4 SPAG5 VCP NLRP5

1.15e-0410588614GO:0007017
GeneOntologyBiologicalProcessestablishment of spindle localization

LLGL2 MAP4 SPAG5 NLRP5

1.31e-0462864GO:0051293
GeneOntologyBiologicalProcessspindle localization

LLGL2 MAP4 SPAG5 NLRP5

1.77e-0467864GO:0051653
GeneOntologyBiologicalProcessmitotic cell cycle process

NCAPG PBRM1 MAP4 WEE1 RBL2 NCAPD2 CKAP5 DYNC1LI1 BCL6 CCDC57 SPAG5 VCP

2.15e-048548612GO:1903047
GeneOntologyBiologicalProcesspositive regulation of cell development

PBRM1 TENM4 VCAN PDE5A BCL6 SPEN IL4R IL23R NLRP3 ITPKA

2.35e-046148610GO:0010720
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell differentiation

BCL6 IL4R IL23R NLRP3

2.46e-0473864GO:0043370
GeneOntologyBiologicalProcesscilium disassembly

MAP4 KIF19

2.55e-046862GO:0061523
GeneOntologyBiologicalProcesspositive regulation of T-helper cell differentiation

IL4R IL23R NLRP3

2.89e-0431863GO:0045624
GeneOntologyBiologicalProcesscardiac muscle hypertrophy

NPPA PDE5A AKAP13 ATP2B4 RYR2

3.21e-04142865GO:0003300
GeneOntologyBiologicalProcesspositive regulation of T cell differentiation

PBRM1 BCL6 IL4R IL23R NLRP3

3.42e-04144865GO:0045582
GeneOntologyBiologicalProcessregulation of the force of heart contraction

PDE5A ATP2B4 RYR2

3.49e-0433863GO:0002026
GeneOntologyBiologicalProcessstriated muscle hypertrophy

NPPA PDE5A AKAP13 ATP2B4 RYR2

3.65e-04146865GO:0014897
GeneOntologyBiologicalProcessmuscle hypertrophy

NPPA PDE5A AKAP13 ATP2B4 RYR2

3.88e-04148865GO:0014896
GeneOntologyBiologicalProcessnon-canonical NF-kappaB signal transduction

ZFP91 BIRC2 NLRP2 NLRP3 VCP

4.13e-04150865GO:0038061
GeneOntologyCellularComponentsupramolecular fiber

WHRN DNAH3 PARP4 PNN MAP4 KIF1B KIF19 CKAP5 DYNC1LI1 AKAP13 CMYA5 CCDC57 ATP2B4 CNP RYR2 SPAG5

2.53e-0511798716GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

WHRN DNAH3 PARP4 PNN MAP4 KIF1B KIF19 CKAP5 DYNC1LI1 AKAP13 CMYA5 CCDC57 ATP2B4 CNP RYR2 SPAG5

2.75e-0511878716GO:0099081
GeneOntologyCellularComponentmicrotubule associated complex

DNAH3 MAP4 KIF1B KIF19 DYNC1LI1 DYNC2I1

5.74e-05161876GO:0005875
GeneOntologyCellularComponentmicrotubule

DNAH3 PARP4 MAP4 KIF1B KIF19 CKAP5 DYNC1LI1 CCDC57 CNP SPAG5

7.35e-055338710GO:0005874
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

WHRN DNAH3 PARP4 PNN MAP4 KIF1B KIF19 CKAP5 DYNC1LI1 AKAP13 CCDC57 CNP SPAG5

8.47e-058998713GO:0099513
GeneOntologyCellularComponentcondensed chromosome, centromeric region

NCAPG PBRM1 NCAPD2 CKAP5 DYNC1LI1 SPAG5

1.56e-04193876GO:0000779
GeneOntologyCellularComponentinterphase microtubule organizing center

DYNC2I1 NLRP3

1.70e-045872GO:0031021
GeneOntologyCellularComponentNatA complex

NAA11 NAA10

1.70e-045872GO:0031415
GeneOntologyCellularComponentcondensed chromosome

NCAPG PBRM1 NCAPD2 CKAP5 DYNC1LI1 RGS12 SPAG5

2.95e-04307877GO:0000793
GeneOntologyCellularComponentmicrotubule organizing center

WHRN PPP4R3B MAP4 NAA11 CKAP5 DYNC1LI1 CDH23 DYNC2I1 CCDC57 IL4R NLRP3 SPAG5

4.13e-049198712GO:0005815
GeneOntologyCellularComponentcondensin complex

NCAPG NCAPD2

4.72e-048872GO:0000796
GeneOntologyCellularComponentparaspeckles

BCL6 NONO

7.54e-0410872GO:0042382
GeneOntologyCellularComponentN-terminal protein acetyltransferase complex

NAA11 NAA10

7.54e-0410872GO:0031414
GeneOntologyCellularComponentchromosome, centromeric region

NCAPG PBRM1 NCAPD2 CKAP5 DYNC1LI1 SPAG5

1.04e-03276876GO:0000775
GeneOntologyCellularComponentcilium

WHRN TBX3 DNAH3 MAP4 VCAN PCDHB15 KIF19 CDH23 DYNC2I1 ATP2B4 SPAG5

1.23e-038988711GO:0005929
GeneOntologyCellularComponentdynein complex

DNAH3 DYNC1LI1 DYNC2I1

1.48e-0354873GO:0030286
GeneOntologyCellularComponentchromosomal region

NCAPG PBRM1 NCAPD2 CKAP5 DYNC1LI1 NLRP2 SPAG5

1.87e-03421877GO:0098687
GeneOntologyCellularComponentSet1C/COMPASS complex

SETD1B BOD1L1

1.98e-0316872GO:0048188
GeneOntologyCellularComponentATPase complex

PBRM1 CECR2 ATP6V0A4 VCP

2.07e-03129874GO:1904949
GeneOntologyCellularComponentextrinsic component of membrane

TGM3 PDE4A TAMM41 CDH23 RYR2

2.74e-03230875GO:0019898
DomainDAPIN

NLRP2 NLRP3 NLRP5

1.41e-0422873PS50824
DomainPYRIN

NLRP2 NLRP3 NLRP5

1.41e-0422873PF02758
DomainDAPIN

NLRP2 NLRP3 NLRP5

1.41e-0422873IPR004020
DomainPYRIN

NLRP2 NLRP3 NLRP5

1.41e-0422873SM01289
DomainNACHT

NLRP2 NLRP3 NLRP5

1.62e-0423873PS50837
DomainNACHT_NTPase

NLRP2 NLRP3 NLRP5

1.62e-0423873IPR007111
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SECISBP2L PARP4 DMXL2 TBC1D9B USF3 PFAS SSH2 MYSM1 MAST3 FARP2

5.59e-07493891015368895
Pubmed

Structural, expression, and evolutionary analysis of mouse CIAS1.

NLRP2 NLRP3 NLRP5

5.63e-07789315302403
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SECISBP2L PHKA2 TBX3 PARP4 DMXL2 LLGL2 PFAS AKAP13 COLGALT1 SPAG5 FARP2

8.72e-07650891138777146
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WHRN SETD1B TENM4 KIF1B FRMPD1 CKAP5 BOD1L1 SPEN ULK2

1.05e-0640789912693553
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

NCOA2 MAP4 BOD1L1 CHD2 SPEN VCP NLRP5

1.13e-0620889733230847
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

PHKA2 NCAPG PNN MAP4 NCAPD2 DYNC1LI1 SPAG5

1.20e-0621089716565220
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TGM3 NCAPG SETD1B PNN MAP4 NCAPD2 CKAP5 DYNC1LI1 PFAS AKAP13 CHD2 COLGALT1 NONO CNP VCP

1.67e-061353891529467282
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

NCAPG PBRM1 CECR2 NCAPD2 CRYBG1 BOD1L1 CHD2 SPEN ZMYM4

3.34e-0646989927634302
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

PNN MAP4 ZFP91 CKAP5 CDH23 AKAP13 SPEN ZMYM4

4.24e-0636189826167880
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

PNN WEE1 KIF1B RALGPS2 AKAP13 RGS12 FARP2

4.33e-0625589715324660
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

DMXL2 NCAPG PBRM1 MAP4 VCAN DYNC1LI1 BOD1L1 NONO CNP

5.43e-0649889936634849
Pubmed

The genetics of NOD-like receptors in Crohn's disease.

NLRP2 NLRP3 NLRP5

5.78e-061489320403135
Pubmed

NALPs: a novel protein family involved in inflammation.

NLRP2 NLRP3 NLRP5

5.78e-061489312563287
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PPP4R3B PBRM1 PNN MAP4 NCAPD2 NAA10 AKAP13 SPEN NONO

5.88e-0650389916964243
Pubmed

Cloning, characterization, and expression analysis of the novel acetyltransferase retrogene Ard1b in the mouse.

NAA11 NAA10

6.48e-06289219246321
Pubmed

Identification of a chromosome-targeting domain in the human condensin subunit CNAP1/hCAP-D2/Eg7.

NCAPG NCAPD2

6.48e-06289212138188
Pubmed

Knocking down ETS Proto-oncogene 1 (ETS1) alleviates the pyroptosis of renal tubular epithelial cells in patients with acute kidney injury by regulating the NLR family pyrin domain containing 3 (NLRP3) transcription.

ETS1 NLRP3

6.48e-06289235611792
Pubmed

BCL6 attenuates hyperoxia-induced lung injury by inhibiting NLRP3-mediated inflammation in fetal mouse.

BCL6 NLRP3

6.48e-06289238419581
Pubmed

The Q705K and F359L Single-Nucleotide Polymorphisms of NOD-Like Receptor Signaling Pathway: Association with Chronic Pancreatitis, Pancreatic Cancer, and Periodontitis.

NLRP2 NLRP3

6.48e-06289226253076
Pubmed

Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression.

ETS1 POU1F1

6.48e-0628929032233
Pubmed

Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation.

NLRP2 NLRP3

6.48e-06289218772453
Pubmed

BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription.

BCL6 NLRP3

6.48e-06289229072703
Pubmed

Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy.

NLRP3 VCP

6.48e-06289227730320
Pubmed

Mutations in NLRP2 and NLRP5 cause female infertility characterised by early embryonic arrest.

NLRP2 NLRP5

6.48e-06289230877238
Pubmed

Centrosome-related genes, genetic variation, and risk of breast cancer.

WEE1 NCAPD2 CKAP5 SPAG5 VCP

6.71e-0610289520508983
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TGM3 PBRM1 PNN MAP4 NCAPD2 CKAP5 PFAS CHD2 SPEN VCP

6.82e-06653891022586326
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PHKA2 RGPD2 LLGL2 PBRM1 WEE1 CKAP5 NAA10 DYNC1LI1 DYNC2I1 NONO ZMYM4 SPAG5 VCP

7.58e-061155891320360068
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TRERF1 PBRM1 CECR2 NCAPD2 DYNC1LI1 POU1F1 COLGALT1 SPEN

8.32e-0639689826687479
Pubmed

Defining the membrane proteome of NK cells.

PARP4 NCAPG PNN CYP20A1 NCAPD2 CKAP5 NAA10 DYNC1LI1 AKAP13 COLGALT1 NONO ATP2B4 CNP

8.54e-061168891319946888
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

PPP4R3B DNAH3 NCAPG PBRM1 NCAPD2 CKAP5 NAA10 DYNC1LI1 BOD1L1 NONO ATP2B4

1.09e-05847891135235311
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

NCAPG PBRM1 PNN NCAPD2 DYNC1LI1 SPEN

1.14e-0519589619454010
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 NCAPG PNN MAP4 NCAPD2 BOD1L1 SPEN NONO ZMYM4

1.18e-0554989938280479
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD MAP4 WEE1 KIF1B RALGPS2 CKAP5 NAA10 AKAP13 BOD1L1 SSH2 RGS12

1.27e-05861891136931259
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

PARP4 MAP4 NCAPD2 CKAP5 CRYBG1 AKAP13

1.39e-0520289633005030
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TGM3 NCAPG PBRM1 PNN MAP4 NCAPD2 CKAP5 DYNC1LI1 PFAS BOD1L1 COLGALT1 CMYA5 SPEN NONO

1.52e-051425891430948266
Pubmed

Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway.

NAA11 NAA10

1.94e-05389234355692
Pubmed

CMYA5 establishes cardiac dyad architecture and positioning.

CMYA5 RYR2

1.94e-05389235449169
Pubmed

Gene body hypomethylation of pyroptosis-related genes NLRP7, NLRP2, and NLRP3 facilitate non-invasive surveillance of hepatocellular carcinoma.

NLRP2 NLRP3

1.94e-05389237273114
Pubmed

Pathological cardiac hypertrophy alters intracellular targeting of phosphodiesterase type 5 from nitric oxide synthase-3 to natriuretic peptide signaling.

NPPA PDE5A

1.94e-05389222829024
Pubmed

Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells.

PDE4A PDE5A

1.94e-05389210393044
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NCOA2 PPP4R3B SETD1B WEE1 KIF1B PFAS SPEN NONO ZMYM4

2.03e-0558889938580884
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NCOA2 MAP4 VCAN FRMPD1 RALGPS2 ETS1 CRYBG1 BOD1L1 CHD2 COLGALT1 ULK2 SPAG5

2.06e-051084891211544199
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

NCAPG PBRM1 MAP4 NCAPD2 CKAP5 BOD1L1 NONO

2.39e-0533289732786267
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TRERF1 NCOA2 PPP4R3B MAP4 ZFP91 CKAP5 ETS1 NAA10 DYNC1LI1 SPEN NONO ZMYM4

2.45e-051103891234189442
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TRERF1 PNN MAP4 WEE1 KIF1B ZFP91 CKAP5 DYNC1LI1 SPEN ZMYM4

2.94e-05774891015302935
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA2 JCAD PARP4 MXRA5 PBRM1 WEE1 CHD2 SPEN RYR2

3.83e-0563889931182584
Pubmed

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity.

KIF1B SPAG5

3.87e-05489220852589
Pubmed

ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97.

ULK2 VCP

3.87e-05489230979586
Pubmed

Conditional knockout of TOG results in CNS hypomyelination.

CKAP5 CNP

3.87e-05489228063167
Pubmed

Identification of mutation gene prognostic biomarker in multiple myeloma through gene panel exome sequencing and transcriptome analysis in Chinese population.

VCAN BCL6

3.87e-05489237406588
Pubmed

The major brain isoform of kif1b lacks the putative mitochondria-binding domain.

NPPA KIF1B

3.87e-05489210341097
Pubmed

Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.

WHRN CDH23

3.87e-05489233009420
Pubmed

Ets-1 promoter-associated noncoding RNA regulates the NONO/ERG/Ets-1 axis to drive gastric cancer progression.

ETS1 NONO

3.87e-05489229773901
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

TGM3 PBRM1 PNN NONO ZMYM4 VCP

4.01e-0524489629884807
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

PARP4 DMXL2 KIF1B CHD2 BCL6 CMYA5 ZMYM4 VCP

4.22e-0549789823414517
Pubmed

Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.

MAP4 NCAPD2 CKAP5 NONO

4.24e-057589429459360
Pubmed

Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.

ZFP91 BIRC2

6.44e-05589234942311
Pubmed

Homeostatic serum IgE is secreted by plasma cells in the thymus and enhances mast cell survival.

BCL6 IL4R

6.44e-05589235301301
Pubmed

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.

WHRN CDH23

6.44e-05589220332152
Pubmed

Deubiquitination and Activation of the NLRP3 Inflammasome by UCHL5 in HCV-Infected Cells.

NLRP3 NLRP5

6.44e-05589234431717
Pubmed

Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1.

NLRP2 NLRP3

6.44e-05589217046979
Pubmed

A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1).

NAA11 NAA10

6.44e-05589219480662
Pubmed

Convallatoxin inhibits IL-1β production by suppressing zinc finger protein 91 (ZFP91)-mediated pro-IL-1β ubiquitination and caspase-8 inflammasome activity.

ZFP91 NLRP3

6.44e-05589234825365
Pubmed

p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor.

NCOA2 NONO

6.44e-05589212810069
Pubmed

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence.

TBX3 RBL2

6.44e-05589222002537
Pubmed

Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.

NAA11 NAA10

6.44e-05589216638120
Pubmed

Zinc finger protein 91 positively regulates the production of IL-1β in macrophages by activation of MAPKs and non-canonical caspase-8 inflammasome.

ZFP91 NLRP3

6.44e-05589230182366
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCOA2 PHKA2 NCAPG RBL2 FRMPD1 NCAPD2 CKAP5 ETS1 SPEN ZMYM4

6.88e-05857891025609649
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

NCOA2 PHKA2 PNN VCP

6.92e-058589416051665
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TRERF1 TBX3 NCAPD2 BOD1L1 SPEN CNP

8.91e-0528289623667531
Pubmed

Chromosome condensation by a human condensin complex in Xenopus egg extracts.

NCAPG NCAPD2

9.65e-05689211136719
Pubmed

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification.

TBX3 NPPA

9.65e-05689220457925
Pubmed

Nitric oxide-dependent downregulation of BRCA1 expression promotes genetic instability.

RBL2 VCP

9.65e-05689223108140
Pubmed

Lack of genetic interaction between Tbx20 and Tbx3 in early mouse heart development.

TBX3 NPPA

9.65e-05689223936153
Pubmed

A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses.

NLRP2 NLRP3

9.65e-05689217435760
Pubmed

Ectopic expression of Nkx2.5 suppresses the formation of the sinoatrial node in mice.

TBX3 NPPA

9.65e-05689221640717
Pubmed

The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart.

TBX3 NPPA

9.65e-05689215158141
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

MAP4 RBL2 CKAP5 PFAS VCP

9.99e-0517989536261009
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NCOA2 PPP4R3B JCAD DMXL2 RBL2 KIF1B CKAP5 DYNC2I1 BIRC2 CMYA5 ZMYM4 VCP

1.06e-041285891235914814
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TGM3 DMXL2 LLGL2 SETD1B BIRC2 SSH2 NONO ULK2 ATP2B4

1.07e-0473089934857952
Pubmed

PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion.

NLRP2 NLRP3

1.35e-04789215817483
Pubmed

Remodeling of the myocardium in early trabeculation and cardiac valve formation; a role for TGFβ2.

TBX3 VCAN

1.35e-04789224623077
Pubmed

Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.

TBX3 NPPA

1.35e-04789219166829
Pubmed

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

NLRP2 NLRP3

1.35e-04789215030775
Pubmed

B cell-intrinsic MyD88 signaling controls IFN-γ-mediated early IgG2c class switching in mice in response to a particulate adjuvant.

BCL6 NLRP3

1.35e-04789231087643
Pubmed

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field.

TBX3 NPPA

1.35e-04789216556915
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SECISBP2L WHRN WEE1 KIF1B RALGPS2 DYNC1LI1 CDH23 DYNC2I1 PDE5A CNP SPAG5 MAST3

1.37e-041321891227173435
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

PBRM1 PNN SPEN ZMYM4

1.46e-0410389432744500
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

TBC1D9B PNN BIRC2 BOD1L1 SPEN FARP2

1.57e-0431389638270169
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

SECISBP2L PPP4R3B PARP4 TAMM41 PNN NCAPD2 PFAS CNP

1.66e-0460689836538041
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

PHKA2 DNAH3 WEE1 NAA10 NONO VCP

1.68e-0431789617620599
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

TGM3 PDE4A USF3 NCAPG MAP4 NCAPD2 DYNC1LI1 CHD2 NONO VCP NLRP5

1.74e-041153891129845934
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRERF1 NCOA2 RGPD2 DMXL2 PDE4A PBRM1 CKAP5 SSH2 ATP2B4 CNP

1.78e-04963891028671696
Pubmed

Cytokine signaling pathway polymorphisms and AIDS-related non-Hodgkin lymphoma risk in the multicenter AIDS cohort study.

BCL6 IL4R

1.79e-04889220299965
Pubmed

Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition.

TBX3 NPPA

1.79e-04889230765799
Pubmed

Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.

NCAPG NCAPD2

1.79e-04889225474630
Pubmed

Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions.

MAP4 CKAP5

1.79e-04889222298430
Pubmed

Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.

NCAPG NCAPD2

1.79e-04889214532007
Pubmed

Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade.

IL4R NLRP3

1.79e-04889225825216
Pubmed

Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling.

TBX3 NPPA

1.79e-04889217460765
GeneFamilyNLR family

NLRP2 NLRP3 NLRP5

8.37e-0525623666
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP2 NLRP3 NLRP5

8.37e-0525623994
GeneFamilyN(alpha)-acetyltransferase subunits|GCN5 related N-acetyltransferases

NAA11 NAA10

7.47e-0412622660
GeneFamilyPDZ domain containing

WHRN FRMPD1 RGS12 MAST3

1.83e-031526241220
GeneFamilyGCN5 related N-acetyltransferases

NAA11 NAA10

3.04e-03246221134
GeneFamilyPhosphodiesterases

PDE4A PDE5A

3.04e-0324622681
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP13 CMYA5

4.43e-0329622396
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KIF1B RALGPS2 AKAP13 FARP2

5.45e-03206624682
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF1B KIF19

1.09e-0246622622
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD1 FARP2

1.28e-02506221293
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

TRERF1 MYSM1

1.43e-0253622532
CoexpressionGSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN

TRERF1 NCOA2 LLGL2 WEE1 KIF1B AKAP13 ATP2B4 NLRP3

3.85e-07198898M6511
CoexpressionGSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP

PHKA2 USF3 RALGPS2 ETS1 COLGALT1 IL4R DISP1

5.33e-06199897M9238
CoexpressionGSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN

NCOA2 PHKA2 LLGL2 NCAPD2 CKAP5 CHD2 MAST3

5.50e-06200897M6745
CoexpressionGSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

TRERF1 TENM4 ETS1 BCL6 CNP RYR2

2.14e-05165896M9105
CoexpressionGSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP

TRERF1 PHKA2 RBL2 NCAPD2 PFAS VCP

3.61e-05181896M6857
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

TRERF1 PPP4R3B PNN RBL2 ETS1 BIRC2 CRYBG1 AKAP13 BOD1L1 CHD2 SSH2 SPEN NONO ATP2B4 MYSM1 MAST3

3.83e-0514928916M40023
CoexpressionBLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP

NCAPG PBRM1 VCAN NCAPD2 CRYBG1 AKAP13 CHD2 NONO

5.43e-05389898M6520
CoexpressionGSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN

PPP4R3B DMXL2 SETD1B BOD1L1 BCL6 NLRP3

5.46e-05195896M7310
CoexpressionGSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_UP

NCOA2 METTL1 DNAH3 NLRP2 NONO RGS12

5.78e-05197896M8159
CoexpressionGSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP

DMXL2 SSH2 ULK2 IL4R CNP FARP2

6.29e-05200896M6369
CoexpressionGSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP

SECISBP2L SETD1B ZFP91 RALGPS2 ETS1 CRYBG1

6.29e-05200896M5069
CoexpressionGSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_UP

TAMM41 FRMPD1 CYP20A1 NCAPD2 CNP SPAG5

6.29e-05200896M9437
CoexpressionGSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN

RALGPS2 DYNC1LI1 AKAP13 SSH2 LDAH MYSM1

6.29e-05200896M9463
CoexpressionLASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN

NCAPG PBRM1 TENM4 KIF1B DYNC1LI1 BIRC2 BOD1L1 SPEN RGS12 ZMYM4 MYSM1

9.04e-058078911M14594
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500

TENM4 MAP4 KIF1B CHD2 NONO MYSM1

3.54e-05150876gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

NCOA2 PPP4R3B DMXL2 USF3 PNN MAP4 CECR2 RALGPS2 DYNC2I1 BIRC2 CHD2 ZMYM4

7.86e-057808712Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

PBRM1 TENM4 MAP4 KIF1B CHD2 NONO MYSM1

9.43e-05259877gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000

PBRM1 TENM4 MAP4 KIF1B CHD2 NONO MYSM1

1.43e-04277877gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlasB cells, proB.FrBC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-1

NCAPG WEE1 CECR2 NCAPD2 RALGPS2 PDE5A CNP SPAG5

1.55e-04376878GSM538418_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#5_top-relative-expression-ranked_200

TENM4 VCAN RYR2 VCP

1.85e-0469874gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k5
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500

DMXL2 TENM4 NAA11 CHD2 NONO MYSM1 RYR2 NLRP5

1.89e-04387878gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

NCOA2 USF3 PNN RALGPS2 DYNC2I1 BIRC2 CHD2

1.94e-04291877Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlasB cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3

NCAPG WEE1 CECR2 NCAPD2 RALGPS2 CKAP5 PDE5A SPAG5

2.74e-04409878GSM399452_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

NCOA2 USF3 PNN CKAP5 BOD1L1 CHD2 SPAG5

2.90e-04311877Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

PHKA2 DMXL2 NCAPG TENM4 NAA11 NONO DISP1 MYSM1 RYR2 NLRP5 FARP2

3.02e-047708711gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_k-means-cluster#3_top-relative-expression-ranked_500

DMXL2 NCAPG NAA11 RYR2

3.12e-0479874gudmap_developingGonad_P2_ovary_500_k3
CoexpressionAtlasB cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R- CD, Fetal Liver, avg-2

NCAPG WEE1 CECR2 NCAPD2 PFAS TCEAL8 ATP2B4 SPAG5

3.22e-04419878GSM538348_500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

DMXL2 NCAPG TENM4 MAP4 NAA11 KIF1B CHD2 NONO MYSM1 RYR2 NLRP5

3.30e-047788711gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000

NCAPG PNN CECR2 VCAN ZFP91 CKAP5 PFAS AKAP13 DISP1 SPAG5 VCP

3.34e-047798711gudmap_developingKidney_e15.5_Cap mesenchyme_1000
ToppCellfacs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM3 MAP4 WEE1 CECR2 ETS1 NONO RGS12

1.18e-07192897ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD TBX3 CECR2 KIF19 SPEN NLRP5

1.15e-061698964e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPPA PNN CYP20A1 CKAP5 CMYA5 RYR2

1.46e-06176896749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 WEE1 CECR2 RALGPS2 ETS1 CNP

1.56e-061788969b932b677ae05ac6e12cd6ce97789f8c10e4790b
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 VCAN KIF1B ZFP91 COLGALT1 NLRP3

1.89e-06184896d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPG NCAPD2 RALGPS2 CKAP5 CNP SPAG5

1.89e-061848968f40093de5bb978f046d66e8f05f333686a009a4
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPG TENM4 NCAPD2 CKAP5 PDE5A SPAG5

2.14e-0618889695d0a796d62ce6d121e2028c378faffc14b35275
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SETD1B ATP6V0A4 FRMPD1 RALGPS2 ULK2

2.45e-06107895410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SETD1B ATP6V0A4 FRMPD1 RALGPS2 ULK2

2.45e-061078955bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USF3 PBRM1 KIF1B ZFP91 CKAP5 ZMYM4

2.49e-06193896abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellCV-Moderate-6|Moderate / Virus stimulation, Condition and Cluster

PDE4A PBRM1 ETS1 AKAP13 BOD1L1 IL4R

2.64e-061958962b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX3 NCAPG NCAPD2 CKAP5 ETS1 SPAG5

2.64e-06195896a838bddeed487154791b69d27a68673783ff63c0
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX3 NCAPG VCAN NCAPD2 CKAP5 PDE5A

2.81e-0619789629b0a5927f80455eef7b793feabef69fba1a3df1
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

TRERF1 DMXL2 NCAPD2 CKAP5 IL4R SPAG5

3.06e-06200896118321ac443feb42aee171baccfc4610f00a8822
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PHKA2 PDE5A CMYA5 DISP1 RIC3

1.16e-05147895b2196046656157d7fcf5b5d1cec7bf521b1e5d8e
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PPP4R3B USF3 RBL2 ETS1 IL4R

1.69e-051598952881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

1.91e-051638955285318c52aa31c9b22dc2ffff078e32e408604d
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 CECR2 RALGPS2 ETS1 CNP

2.02e-0516589522293c6b55f44636440cd737efb786ff5de3373d
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SECISBP2L USF3 RALGPS2 ETS1 IL4R

2.27e-05169895c3a6179a64589a370108fea809b157839347759c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPG VCAN NCAPD2 CKAP5 SPAG5

2.27e-05169895563c267edaade0e5df192ad953801ef9768d4270
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

2.27e-05169895e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGM3 PDE5A BOD1L1 BCL6 ATP2B4

2.40e-051718952b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGM3 PDE5A BOD1L1 BCL6 ATP2B4

2.40e-05171895dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD AKAP13 ATP2B4 DISP1 ITPKA

2.75e-05176895a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

TBX3 MXRA5 PCDHB15 PDE5A RYR2

2.75e-05176895852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

TBX3 MXRA5 PCDHB15 PDE5A RYR2

2.75e-05176895d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WEE1 CECR2 RALGPS2 ETS1 CNP

2.83e-05177895a58c93be9767e3fe8fbb6b0db1210d3a33aac662
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WEE1 CECR2 RALGPS2 ETS1 CNP

2.83e-051778953ed383e5c0b15d9d5e75b98cf6d10609f48fc422
ToppCellMild-Lymphoid-T-innate_T|Mild / Condition, Lineage, Cell class and cell subclass

RBL2 ETS1 ATP2B4 IL23R ITPKA

2.99e-05179895abc0fbe101a464a2c85755a974a3d5c2b968fe46
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPG NCAPD2 CKAP5 SPAG5 ITPKA

2.99e-05179895ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

3.07e-05180895334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 NCAPG NCAPD2 CKAP5 COLGALT1

3.40e-0518489516aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD ATP2B4 RYR2 MAST3 ITPKA

3.59e-0518689556c139e679d640ea901ead657a8e8887e0fca098
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPG CECR2 NCAPD2 CKAP5 SPAG5

3.59e-051868953993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPG CECR2 NCAPD2 CKAP5 SPAG5

3.59e-05186895ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellE12.5-Mesenchymal|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TBX3 TENM4 VCAN PDE5A TCEAL8

3.77e-051888959778dadc2bd7ded3a723e717d1c8cd3160e99c6c
ToppCellControl-Myeloid-Monocytes|Control / group, cell type (main and fine annotations)

DMXL2 VCAN CDH23 SSH2 NLRP3

3.87e-051898953335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

JCAD TBX3 ETS1 ATP2B4 DISP1

3.87e-05189895b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TBX3 NCAPG NCAPD2 CKAP5 SPAG5

3.87e-05189895d049f33115610bda4489968759f754730698b9cd
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

3.87e-051898951e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE4A VCAN CRYBG1 BCL6 NLRP3

3.97e-05190895ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD PBRM1 MAP4 ETS1 PDE5A

3.97e-05190895d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NCAPG NCAPD2 CKAP5 PDE5A SPAG5

4.07e-05191895f764cc21fef87ebad765011098f647ae1bdf6158
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPG TENM4 NCAPD2 CKAP5 PDE5A

4.27e-05193895a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JCAD TBX3 ETS1 ATP2B4 DISP1

4.27e-05193895a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CECR2 RALGPS2 CKAP5 ETS1 CNP

4.38e-051948958ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMXL2 NCAPG NCAPD2 COLGALT1 SPAG5

4.49e-05195895c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellCOVID-19_Mild-PLT_5|COVID-19_Mild / Disease Group and Platelet Clusters

TRERF1 VCAN NCAPD2 ETS1 ATP2B4

4.49e-05195895bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

TRERF1 CRYBG1 AKAP13 ATP2B4 RYR2

4.49e-051958956687e579582d7a239bee80846de0cf827a6f6a62
ToppCellCOPD-Lymphoid-T|COPD / Disease state, Lineage and Cell class

TRERF1 ETS1 CRYBG1 ATP2B4 RYR2

4.60e-0519689530e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

PDE4A PBRM1 AKAP13 BOD1L1 IL4R

4.60e-051968957bced0cc2112697593c478fa291b8ed3941fb811
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LLGL2 RBL2 KIF19 ETS1 ATP2B4

4.71e-051978952b3a56bb1d40bc1284a5931c4e7b373660de5402
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_Tem|COVID-19_Severe / Disease group, lineage and cell class

LLGL2 RBL2 KIF19 ETS1 ATP2B4

4.71e-05197895f0bac4d5c3160933ac3786cec8dadffb35d711ea
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LLGL2 RBL2 KIF19 ETS1 ATP2B4

4.71e-05197895f73ece3aca28c0db5db0f12e026d42c6c36b9efb
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LLGL2 RBL2 KIF19 ETS1 ATP2B4

4.71e-05197895e70e7d97823a762def3970d94a0e897981a6c922
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LLGL2 RBL2 KIF19 ETS1 ATP2B4

4.71e-05197895bce0135a96910d2bace62a3408a1a6fdac0cf0df
ToppCellNon-neuronal-Dividing-IPC-IPC-div1-28|World / Primary Cells by Cluster

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

4.94e-05199895787688b68ae5d8768c0a24673ae07ab07616764a
ToppCellNon-neuronal-Dividing-IPC-IPC-div1|World / Primary Cells by Cluster

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

4.94e-0519989572823f26ecabcae1b514b7629cfce010c97b929a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

4.94e-05199895ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCellCOVID-19_Moderate-CD4+_CTL|World / disease group, cell group and cell class

LLGL2 RBL2 KIF19 ETS1 ATP2B4

4.94e-0519989512ea0346b4da3e8e2b3b2b3b3e9d4f4f104345a6
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MXRA5 VCAN RALGPS2 DYNC1LI1 IL4R

4.94e-05199895e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

4.94e-05199895d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MXRA5 VCAN BCL6 IL4R RYR2

4.94e-051998958b86c69aaf60feff53aa782559cfece7342a23de
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

4.94e-0519989598575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

4.94e-05199895be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WHRN VCAN PDE5A RGS12

5.04e-051018946523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

5.06e-052008954cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD8+_Tem|COVID-19_Severe / Disease, condition lineage and cell class

LLGL2 RBL2 KIF19 ETS1 ATP2B4

5.06e-0520089531859b8db7ea17e48b7b54e92f0d76aeb755e7ca
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

NCAPG WEE1 NCAPD2 CKAP5 SPAG5

5.06e-052008959bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial|2m / Sample Type, Dataset, Time_group, and Cell type.

TBX3 MXRA5 VCAN ETS1 PDE5A

5.06e-052008953da9441c0f1e242f0d195de47ecd4c24dfdca232
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial-Proteoglycan-expressing_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

TBX3 MXRA5 VCAN ETS1 PDE5A

5.06e-05200895eed2bafddcd041ef5fcc4d1d31edb8be4d83ce01
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

TBX3 PNN VCAN BOD1L1 SPEN

5.06e-052008957c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PNN VCAN SPEN MYSM1

6.32e-05107894c41bc8810df67158f0ae9f6015c965a8ebd96965
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PNN VCAN SPEN MYSM1

6.32e-0510789460b272f5c89bea8a2714f870e18b7ac89a4a4bf6
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1|Hippocampus / BrainAtlas - Mouse McCarroll V32

SECISBP2L KIF19 BIRC2 CNP

7.29e-05111894bb59f1909645fd512f0ea806e5593d4a1c6e25d9
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PARP4 TBC1D9B SPEN CCDC57

8.08e-05114894670c9802a59b39241abf6f2c12a3d1844c7db5e5
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SECISBP2L KIF19 BIRC2 CNP

8.94e-0511789413f068cc4b4a8e9c66bf0e9e5acf9613654bf3f4
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WHRN NPPA FRMPD1 PDE5A

1.19e-041268943539a8fdbb52d191f36dce68c38798ad4d2b491a
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

TBX3 MXRA5 VCAN VCP

1.30e-0412989413cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 CRYBG1 PFAS CMYA5

1.55e-041358947b456fa9a5f5ce58976a8f1fad18c0f96a096930
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Otof_(Layer_2/3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NAA11 NLRP2 IL23R

1.63e-0453893a41f66edf468f824494a922c3addf429a9125b7f
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SECISBP2L KIF19 BIRC2 CNP

1.64e-0413789480f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCellLA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NPPA MXRA5 RYR2 ITPKA

1.74e-041398949e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 BIRC2 IL23R SPAG5

1.79e-0414089411e441c3435ad8911ab401ca7d4ae1d3e5fa6eac
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 BIRC2 IL23R SPAG5

1.79e-0414089494444b92acfad64d811ebb1545dc1dab64473795
ToppCell367C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

WHRN MAP4 ZMYM4

1.82e-04558937916216b3a24f9c6b966aa5392fc2bc43b3d2c4c
ToppCellprimary_visual_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

WHRN LLGL2 PNN ATP2B4

1.84e-04141894605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

JCAD TBX3 CDH23 SPAG5

1.94e-04143894ce045ec7c311a1797ae562bec114f9e90604d063
ToppCellMild/Remission-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SECISBP2L USF3 ETS1 IL4R

2.21e-04148894dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PHKA2 PDE5A CMYA5 DISP1

2.27e-041498944034805c4eefb8bfb3a357273ccbdb77283ea4a5
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PNN RBL2 SPEN MYSM1

2.51e-04153894553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PNN RBL2 SPEN MYSM1

2.51e-0415389488ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCelldroplet-Fat-SCAT-30m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 TENM4 KIF19 SPAG5

2.51e-041538942731c3d4ac40ecc22108f8f3f45a069077159125
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGM3 DNAH3 KIF19 SAMD15

2.57e-041548949ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGM3 DNAH3 KIF19 SAMD15

2.57e-0415489458072ce422d09f2de602580325eaac6c4ec6c136
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD LLGL2 CMYA5 ATP2B4

2.57e-0415489412cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PPP4R3B USF3 ETS1 IL4R

2.63e-041558940a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD LLGL2 CMYA5 ATP2B4

2.70e-04156894fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TGM3 ATP2B4 SPAG5 ITPKA

2.70e-041568942cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 VCAN BCL6 NLRP3

2.77e-04157894a98d06cef80bfe8481b0940abce2b29675e45812
DrugGinkgolide A [15291-75-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A

PHKA2 PDE4A TBC1D9B MAP4 WEE1 AKAP13 BCL6 IL4R

1.10e-061988983260_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

NCOA2 PPP4R3B METTL1 TBX3 SETD1B TENM4 CYP20A1

5.70e-061758974072_DN
Drugcilostamide

NPPA PDE4A PBRM1 RBL2 VCAN PDE5A

7.69e-06120896CID000002753
DrugEstriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

PPP4R3B TBC1D9B MAP4 AKAP13 IL4R ZNF783 MAST3

1.01e-051918977220_DN
Drugvinblastine sulfate; Up 200; 0.1uM; PC3; HT_HG-U133A

PPP4R3B JCAD PHKA2 PDE4A TBC1D9B IL4R MAST3

1.04e-051928977556_UP
DrugHarmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A

TENM4 MAP4 PCDHGA1 IL4R RGS12 RYR2 MAST3

1.16e-051958972805_UP
DrugPhenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; MCF7; HT_HG-U133A

SECISBP2L PHKA2 PDE4A MAP4 IL4R RGS12 FARP2

1.19e-051968973217_DN
Drug(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

SECISBP2L WHRN TBX3 FRMPD1 PDE5A ZNF783 MAST3

1.23e-051978974138_UP
DrugAC1L1IZE

PHKA2 DNAH3 RBL2 DYNC1LI1 ATP2B4 RYR2

1.27e-05131896CID000004799
DrugMianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

TENM4 ULK2 IL4R ZNF783 RYR2 MAST3 FARP2

1.28e-051988975786_DN
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A

PHKA2 MAP4 AKAP13 IL4R RGS12 CNP ZNF783

1.32e-051998971509_DN
DrugThiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PHKA2 DMXL2 TENM4 VCAN ATP6V0A4 IL4R RYR2

1.36e-052008972894_UP
DrugIsoammodendrine

PNN AKAP13

1.51e-052892CID000108191
Drugrolipram

NPPA PDE4A MAP4 POU1F1 PDE5A AKAP13 IL4R

6.11e-05253897CID000005092
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

SECISBP2L WHRN PDE4A MAP4 BCL6 MAST3

7.82e-051818967453_UP
DrugDynese

VCAN SPEN

9.02e-054892CID003086011
DrugDipyridamole

PDE4A PDE5A

9.02e-054892DB00975
DrugGSK-3beta Inhibitor VIII; Down 200; 10uM; MCF7; HT_HG-U133A

WHRN PHKA2 CYP20A1 RALGPS2 CCDC57 ULK2

1.08e-041928967092_DN
DrugGlycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A

NCOA2 TBX3 DMXL2 VCAN RALGPS2 BCL6

1.14e-041948964709_UP
DrugKhellin [82-02-0]; Up 200; 15.4uM; MCF7; HT_HG-U133A

TBX3 RALGPS2 AKAP13 RGS12 ZNF783 MAST3

1.14e-041948964987_UP
Drug(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A

WHRN PHKA2 DNAH3 MAP4 ULK2 RYR2

1.14e-041948963539_DN
DrugUngerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A

NCOA2 PHKA2 MAP4 ULK2 ATP2B4 MAST3

1.14e-041948966076_DN
DrugClozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A

NCOA2 DMXL2 MAP4 RBL2 RGS12 RYR2

1.18e-041958965265_UP
DrugKarakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A

NCOA2 PHKA2 MAP4 CYP20A1 RALGPS2 RYR2

1.18e-041958966059_DN
DrugPirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A

SECISBP2L DNAH3 MAP4 ATP2B4 IL4R ZNF783

1.21e-041968967226_DN
DrugDiphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HT_HG-U133A

PDE4A PBRM1 WEE1 PDE5A RGS12 RYR2

1.21e-041968964591_UP
DrugSR-95639A [115767-94-7]; Down 200; 10uM; MCF7; HT_HG-U133A

PDE4A TBC1D9B MAP4 IL4R RGS12 CNP

1.21e-041968963272_DN
DrugPropafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A

WHRN PBRM1 PCDHGA1 RALGPS2 ATP2B4 FARP2

1.21e-041968962871_UP
DrugRepaglinide [135062-02-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

NCOA2 WHRN TBX3 NPPA VCAN ULK2

1.21e-041968963558_UP
DrugIpratropium bromide [22254-24-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A

WHRN TENM4 MAP4 RALGPS2 RGS12 MAST3

1.21e-041968962762_UP
DrugDehydrocholic acid [81-23-2]; Down 200; 9.6uM; HL60; HG-U133A

NPPA MAP4 LDAH IL4R CNP ZNF783

1.21e-041968962023_DN
DrugMeticrane [1084-65-7]; Down 200; 14.6uM; MCF7; HT_HG-U133A

NCOA2 PHKA2 MAP4 ATP2B4 IL4R ZNF783

1.24e-041978961671_DN
DrugChlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; MCF7; HT_HG-U133A

NCOA2 DNAH3 MAP4 RBL2 ATP2B4 IL4R

1.24e-041978965360_UP
DrugRicinine [524-40-3]; Up 200; 24.4uM; MCF7; HT_HG-U133A

TBX3 DMXL2 NAA11 ATP2B4 RGS12 RYR2

1.24e-041978966067_UP
DrugVinpocetine [42971-09-5]; Down 200; 11.4uM; MCF7; HT_HG-U133A

NCOA2 PPP4R3B MAP4 ULK2 IL4R MAST3

1.24e-041978967213_DN
Drugnordihydroguaiaretic acid; Up 200; 1uM; MCF7; HG-U133A

DNAH3 RBL2 CHD2 BCL6 ULK2 FARP2

1.24e-04197896203_UP
DrugMetoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; HL60; HT_HG-U133A

SECISBP2L MAP4 SPEN IL4R ZNF783 RIC3

1.24e-041978962353_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A_EA

NCOA2 TBC1D9B PNN MAP4 CYP20A1 LDAH

1.24e-041978961055_UP
DrugOxaprozin [21256-18-8]; Down 200; 13.6uM; PC3; HT_HG-U133A

NCOA2 JCAD WEE1 RBL2 IL4R ITPKA

1.24e-041978964530_DN
DrugIsoflupredone acetate [338-98-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A

MAP4 CYP20A1 AKAP13 RGS12 RYR2 MAST3

1.28e-041988965545_DN
DrugEbselen [60940-34-3]; Up 200; 14.6uM; PC3; HT_HG-U133A

WHRN ETS1 AKAP13 CCDC57 LDAH RYR2

1.28e-041988965778_UP
DrugNifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A

WHRN JCAD NPPA VCAN RALGPS2 BCL6

1.28e-041988962285_UP
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; HL60; HG-U133A

DMXL2 SETD1B RBL2 CNP ZNF783 VCP

1.28e-041988961970_DN
DrugAcetopromazine maleate salt [3598-37-6]; Up 200; 9uM; PC3; HT_HG-U133A

PDE4A FRMPD1 CYP20A1 ETS1 ATP2B4 LDAH

1.32e-041998964494_UP
Drugvaldecoxib; Down 200; 10uM; MCF7; HT_HG-U133A

TBX3 NPPA DMXL2 VCAN BCL6 ULK2

1.32e-041998966403_DN
Drugaspirin, USP; Up 200; 100uM; MCF7; HG-U133A

TGM3 DNAH3 FRMPD1 NLRP2 IL4R MAST3

1.32e-04199896315_UP
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A

PDE4A MAP4 ULK2 RGS12 ZNF783 FARP2

1.32e-041998966982_UP
Drug5186223; Up 200; 12uM; MCF7; HT_HG-U133A_EA

NCOA2 PPP4R3B TBX3 DNAH3 AKAP13 ULK2

1.35e-04200896885_UP
DrugFenbendazole [43210-67-9]; Down 200; 13.4uM; PC3; HT_HG-U133A

WHRN JCAD VCAN BCL6 MAST3 ITPKA

1.35e-042008964542_DN
DrugKetotifen fumarate [34580-14-8]; Down 200; 9.4uM; PC3; HT_HG-U133A

WHRN JCAD TBC1D9B VCAN AKAP13 MAST3

1.35e-042008965842_DN
Drugoctogen

TRERF1 PBRM1 NLRP3

1.41e-0426893CID000017596
DrugRo 15-2041

NPPA PDE4A PDE5A

1.41e-0426893CID000132434
Drugbronopol

VCAN FARP2

1.50e-045892CID000002450
DrugD-22888

PDE4A PDE5A

1.50e-045892CID000197714
DiseaseOgden syndrome (implicated_via_orthology)

NAA11 NAA10

8.59e-062872DOID:0050781 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

PPP4R3B TBX3 TENM4 RALGPS2 BCL6 ATP2B4 LDAH RGS12 RYR2 ITPKA

2.83e-056708710EFO_0006335, EFO_0006336
Diseasemonocyte percentage of leukocytes

TRERF1 CECR2 KIF1B ETS1 CDH23 AKAP13 SSH2 BCL6 ZMYM4 NLRP3

5.88e-057318710EFO_0007989
Diseasemultiple sclerosis (is_implicated_in)

KIF1B IL4R CNP IL23R

6.57e-0573874DOID:2377 (is_implicated_in)
Diseasemyocardial infarction (biomarker_via_orthology)

TBX3 NPPA VCAN IL4R NLRP3

1.14e-04160875DOID:5844 (biomarker_via_orthology)
Diseasemonocyte count

JCAD CECR2 VCAN KIF1B ETS1 CDH23 PDE5A AKAP13 SSH2 BCL6 ATP2B4 DISP1 VCP

1.27e-0413208713EFO_0005091
DiseaseHereditary retinal dystrophy

WHRN CDH23

1.79e-047872C0154860
DiseaseMalignant neoplasm of breast

TRERF1 NCOA2 TBX3 TBC1D9B LLGL2 PBRM1 PCDHB15 FRMPD1 BIRC2 BOD1L1 SPEN

3.15e-0410748711C0006142
Diseasemyeloid white cell count

JCAD SETD1B KIF1B ETS1 CDH23 SSH2 COLGALT1 ATP2B4 SAMD15 NLRP3

4.36e-049378710EFO_0007988
DiseaseChronic Lymphocytic Leukemia

RBL2 BCL6 FARP2

5.81e-0455873C0023434
Diseaseneutrophil percentage of granulocytes

TRERF1 ETS1 AKAP13 ITPKA FARP2

5.82e-04228875EFO_0007994
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

DMXL2 CDH23

6.56e-0413872C1846647
Diseaseneutrophil count

TRERF1 JCAD KIF1B ETS1 CDH23 AKAP13 SSH2 SAMD15 ZMYM4 NLRP3 ITPKA FARP2

7.30e-0413828712EFO_0004833
Diseasedigit length ratio

ETS1 LDAH

1.00e-0316872EFO_0004841
Diseaseallergic disease

ETS1 BCL6 IL4R ZMYM4 ITPKA

1.01e-03258875MONDO_0005271
Diseasepsoriasis

NPPA PDE4A ETS1 AKAP13 IL23R

1.30e-03273875EFO_0000676
Diseasemultiple sclerosis

NCOA2 METTL1 PDE4A KIF1B ETS1 AKAP13 BCL6

1.88e-03594877MONDO_0005301
Diseaseprogranulin measurement

NCOA2 CDH23

1.91e-0322872EFO_0004625
Diseasebasophil percentage of granulocytes

NCOA2 ETS1 BCL6

1.92e-0383873EFO_0007995
Diseaseplatelet crit

NCOA2 JCAD TGM3 DNAH3 PDE4A ETS1 PDE5A ATP2B4 NLRP3

1.97e-03952879EFO_0007985
DiseaseEczema

ETS1 BCL6 IL4R ZMYM4 ITPKA

2.27e-03310875HP_0000964
Diseaselymphoma

ZFP91 BCL6

2.27e-0324872EFO_0000574
DiseaseProstatic Neoplasms

NCOA2 TBX3 NPPA AKAP13 SPEN LDAH VCP

2.31e-03616877C0033578
DiseaseMalignant neoplasm of prostate

NCOA2 TBX3 NPPA AKAP13 SPEN LDAH VCP

2.31e-03616877C0376358
Diseasepulse pressure measurement

JCAD NPPA MXRA5 PBRM1 TENM4 CYP20A1 RALGPS2 CKAP5 AKAP13 CHD2 LDAH

2.58e-0313928711EFO_0005763

Protein segments in the cluster

PeptideGeneStartEntry
HLEEKMPLEDEVVPP

NPPA

46

P01160
TDPVHDLMAEILPEF

VCAN

1361

P13611
MDSIIFPKPEEEHLA

AKAP13

1451

Q12802
KDQPDFISHRMDDVP

DMXL2

1921

Q8TDJ6
DRENPDPHEAELMRK

CDH23

841

Q9H251
IEEHLPKMAEPSSFV

DISP1

1381

Q96F81
SMERPESPKEFLDLD

CECR2

1306

Q9BXF3
FMTHPEFAIEEELPR

ATP2B4

1166

P23634
EDMANLPPHFRERTE

RBL2

136

Q08999
FIHPEETEHEPTKMF

PBRM1

1196

Q86U86
FRKSPEHPVDDIDKM

KIAA0100

2091

Q14667
LPPDITEEEMRKLFE

NONO

81

Q15233
ELAKEIEMASEERPP

MAP4

221

P27816
EPLEVAHDLSKSPDM

LLGL2

791

Q6P1M3
LLPTEMEKTHEDRPF

KIF1B

806

O60333
MEKTHEDRPFPRTVV

KIF1B

811

O60333
PVKSESHLPDRDMDN

JCAD

586

Q9P266
PPVRKFVHEKEIMAE

DYNC1LI1

356

Q9Y6G9
LRKESEMDLPEHKEP

DYNC2I1

41

Q8WVS4
PEELHAMLDVKPDAD

ETS1

426

P14921
ASKELEPEMEFEIEP

PNN

421

Q9H307
PHRPIERADAMDTSD

PDE4A

61

P27815
KEQMPLTPPRFDHDE

PDE5A

131

O76074
VLAKMEEDPDDVPHG

NAA10

56

P41227
PPLDVDEMLERFKTE

NLRP2

116

Q9NX02
KARDDMKRHSPEDPE

NLRP5

141

P59047
PDPKELSAEEIAERM

RIC3

251

Q7Z5B4
RFEEMPETSHLIDLP

PPP4R3B

121

Q5MIZ7
MDLHEKDFSLTEAPP

PARP4

511

Q9UKK3
INDHSPEFPEREMTL

PCDHB15

126

Q9Y5E8
KMLAVDPEAPTEEEH

ITPKA

291

P23677
DPMEDPDDILRAHRS

KIF19

46

Q2TAC6
ADPKEVEEEERHMPK

BOD1L1

2756

Q8NFC6
EPKIRAVSPHFDDMH

CKAP5

1521

Q14008
DPLLARHLEEVEPEM

IL4R

516

P24394
PDKMVPAVREFIAEH

DNAH3

3481

Q8TD57
EEEFEMLHKSIPVDP

CHD2

1226

O14647
TEEEDRDLEAHPMAP

FRMPD1

1351

Q5SYB0
MSPEVEHKEEELILP

CMYA5

551

Q8N3K9
DPMITEIKEIFIPEH

IL23R

431

Q5VWK5
EDVLDPLKMSSPHAE

CCDC57

601

Q2TAC2
FVPGDEPREKMDLVT

CNP

226

P09543
PKETIPEEARSDMHY

BCL6

261

P41182
KDPLEEMVPLSHLEE

MAST3

326

O60307
AMPPIHEDHLEKVFD

CRYBG1

731

Q9Y4K1
PHKFDPDRFDDELVM

CYP20A1

381

Q6UW02
VDEFLPVMFDKHPVS

COLGALT1

521

Q8NBJ5
MDCEEPRHKRVPADE

FARP2

521

O94887
MDETHKESDLEPPEE

SAMD15

126

Q9P1V8
KEPNPEAEELFRMVA

RYR2

3386

Q92736
RNSDVRHAPAEEMPE

PRRT3

71

Q5FWE3
DEEYKNPHTVDRVPM

PHKA2

381

P46019
MADDPEHPDLFLLTD

RALGPS2

526

Q86X27
HPEMVLQSPLDREEE

PCDHGA1

191

Q9Y5H4
SPIKMELLFDPDDEH

NLRP3

201

Q96P20
EEREMRFPTHPKESE

SPAG5

276

Q96R06
FKEDTPVRHLDPEEM

TCEAL8

61

Q8IYN2
HLRPLKTMEPEEEVE

TBX3

86

O15119
DDIHFEPVVQMPEKV

RGPD2

1026

P0DJD1
PIDMDSPEIRELEKF

POU1F1

121

P28069
EEVPLTPEHRMLVEK

FAM178B

236

Q8IXR5
EPTEMHLDFIDDLPQ

SECISBP2L

601

Q93073
GPEKPHDSLDSRIEM

SETD1B

491

Q9UPS6
FVMVEVHRPDSEPDV

WHRN

721

Q9P202
MSLDPEEEAEHPIKI

TGM3

541

Q08188
EEIERDLHRSMPEHP

TBC1D9B

551

Q66K14
EPKDDAMSEHRRHFP

BIRC2

231

Q13490
DPELGVEEEPFHTIM

NCAPD2

1176

Q15021
DHEVPEPESEMKMRL

NCAPG

976

Q9BPX3
RMLVKPLPDSEEEGH

NCOA2

201

Q15596
EFTELLKVMIHPDPE

WEE1

541

P30291
ADDVLRAPHPDMFKE

RGS12

791

O14924
MGDHENRSPVKEPVE

SPEN

1911

Q96T58
VLAKMEEEPDDVPHG

NAA11

56

Q9BSU3
EAPPEHSFVLKEPEM

SSH2

916

Q76I76
DPVPEIRRDHFEEAM

VCP

726

P55072
DHISKEAPEPGMEVV

PFAS

436

O15067
DMEADTVLSPEHPVR

TENM4

116

Q6N022
MDHPDFSSENPKIVD

USF3

1026

Q68DE3
PPMVVEVHDRDRKSE

nan

51

Q6ZUG5
HIMDPPGKNRDVEET

TAMM41

261

Q96BW9
PELPEETLMEREHTD

ULK2

811

Q8IYT8
FSEMDAPLEDPVTKE

ATP6V0A4

201

Q9HBG4
EMLISEEEIPFKDDP

ZFP91

216

Q96JP5
EMAEAPASVRDDPRH

ZSCAN5C

146

A6NGD5
ADHTLRYPVKPEEMD

METTL1

31

Q9UBP6
EKLPTHPFEADLLEM

ZMYM4

1036

Q5VZL5
MAEAAPARDPETDKH

ZNF783

1

Q6ZMS7
SDDEMPVLEIPRKHQ

TRERF1

621

Q96PN7
MDSELKEEIPVHEEF

LDAH

1

Q9H6V9
LEPMEKPIFHDPISE

MXRA5

2536

Q9NR99
QMVEESHEEEELKPP

MYSM1

361

Q5VVJ2