Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhelicase activity

RAD54L2 DDX10 DQX1 MOV10L1 RECQL4 RAD51 DDX12P DDX49 WRN

3.81e-051582059GO:0004386
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA2 CCT3 KIF1A RAD54L2 DDX10 DQX1 MOV10L1 RECQL4 RAD51 DDX12P DDX49 ATP13A1 WRN RNF213 CCT6A

5.37e-0544120515GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

ABCA2 ATP6V0A1 CCT3 KIF1A RAD54L2 DDX10 DQX1 MOV10L1 RECQL4 RAD51 DDX12P DDX49 ATP13A1 WRN RNF213 CCT6A ATP4B

2.11e-0461420517GO:0140657
DomainEGF

ITGB5 STAB1 STAB2 THBS2 MEGF6 HMCN1 SLIT1 FBN3

6.64e-051262018PF00008
DomainGFP-like

STAB1 STAB2 HMCN1

1.90e-04112013IPR023413
Domain-

STAB1 STAB2 HMCN1

1.90e-041120132.40.155.10
DomainEGF

ADAM15 ITGB5 GPR179 STAB1 STAB2 THBS2 MEGF6 HMCN1 SLIT1 FBN3

2.39e-0423520110SM00181
DomainEGF_dom

STAB1 STAB2 THBS2

2.51e-04122013IPR024731
DomainEGF_3

STAB1 STAB2 THBS2

2.51e-04122013PF12947
DomainGrowth_fac_rcpt_

GPR179 STAB1 STAB2 IGFBP2 MEGF6 HMCN1 SLIT1 FBN3

2.92e-041562018IPR009030
DomainHRDC

EXOSC10 WRN

3.43e-0432012PS50967
DomainPellino

PELI2 PELI1

3.43e-0432012PF04710
DomainHRDC

EXOSC10 WRN

3.43e-0432012SM00341
DomainHRDC

EXOSC10 WRN

3.43e-0432012PF00570
DomainPellino_fam

PELI2 PELI1

3.43e-0432012IPR006800
DomainEGF_CA

STAB1 STAB2 THBS2 MEGF6 HMCN1 SLIT1 FBN3

3.55e-041222017SM00179
DomainEGF-like_Ca-bd_dom

STAB1 STAB2 THBS2 MEGF6 HMCN1 SLIT1 FBN3

3.92e-041242017IPR001881
DomainEGF_extracell

ADAM15 ITGB5 STAB1 STAB2 MEGF6

4.64e-04602015IPR013111
DomainEGF_2

ADAM15 ITGB5 STAB1 STAB2 MEGF6

4.64e-04602015PF07974
DomainBROMODOMAIN_1

BRWD3 TRIM66 PHIP BRWD1

6.51e-04372014PS00633
DomainFAS1

STAB1 STAB2

6.82e-0442012SM00554
DomainFasciclin

STAB1 STAB2

6.82e-0442012PF02469
DomainFAS1_domain

STAB1 STAB2

6.82e-0442012IPR000782
DomainHRDC_dom

EXOSC10 WRN

6.82e-0442012IPR002121
Domain-

STAB1 STAB2

6.82e-04420122.30.180.10
DomainFAS1

STAB1 STAB2

6.82e-0442012PS50213
DomainBromodomain

BRWD3 TRIM66 PHIP BRWD1

7.22e-04382014PF00439
DomainBROMODOMAIN_2

BRWD3 TRIM66 PHIP BRWD1

9.65e-04412014PS50014
DomainBromodomain

BRWD3 TRIM66 PHIP BRWD1

1.06e-03422014IPR001487
Domain-

BRWD3 TRIM66 PHIP BRWD1

1.06e-034220141.20.920.10
DomainBROMO

BRWD3 TRIM66 PHIP BRWD1

1.06e-03422014SM00297
DomainHelicase_C

RAD54L2 DDX10 DQX1 RECQL4 DDX49 WRN

1.11e-031082016IPR001650
DomainDNA_helicase_ATP-dep_RecQ

RECQL4 WRN

1.13e-0352012IPR004589
Domain35EXOc

EXOSC10 WRN

1.13e-0352012SM00474
DomainPAN_AP

MST1 MST1L

1.13e-0352012SM00473
DomainDNA_pol_A_exo1

EXOSC10 WRN

1.13e-0352012PF01612
DomainHRDC-like

EXOSC10 WRN

1.13e-0352012IPR010997
DomainSterol-sensing

HMGCR PTCH2

1.13e-0352012PF12349
Domain3'-5'_exonuclease_dom

EXOSC10 WRN

1.13e-0352012IPR002562
DomainDEXDc

RAD54L2 DDX10 DQX1 RECQL4 DDX49 WRN

1.17e-031092016SM00487
DomainHELICASE_CTER

RAD54L2 DDX10 DQX1 RECQL4 DDX49 WRN

1.17e-031092016PS51194
DomainHELICASE_ATP_BIND_1

RAD54L2 DDX10 DQX1 RECQL4 DDX49 WRN

1.17e-031092016PS51192
DomainHelicase_ATP-bd

RAD54L2 DDX10 DQX1 RECQL4 DDX49 WRN

1.22e-031102016IPR014001
DomainPSI

ITGB5 SEMA4A PLXNB3 SEMA4G

1.26e-03442014IPR016201
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CFH TET2 ABCA2 ATP6V0A1 AKAP17A KIF1A MYCBP2 NCKAP5 RAD54L2 BRWD3 TRAPPC1 ME3 STAT6 STAB1 TTLL12 TRIM66 DIP2A MTA3 SACS ADAMTS9 AFDN PLXNB3 BRWD1 ATP13A1 RANBP9 SHROOM2 CDC42BPB GMCL1 WDFY3

1.27e-0912852112935914814
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCA2 MYCBP2 PFAS NPHP4 ITGB5 NSD3 DIP2A EIF4ENIF1 NLGN2 RAD51 LRRC8E ZNF628 SZT2 ATP13A1 TSNARE1 L1CAM KSR2 TTYH3 ZBTB42 GBA2 CDC42BPB KLHL25 MEGF6 ZFYVE26 WDFY3 STK40

4.19e-0911052112635748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SECISBP2L RASSF2 PFAS NPHP4 TRIM66 SACS ADAMTS9 NLGN2 ATP13A1 RNF213 TTYH3 GBA2 CDC42BPB SEMA4G MEGF6 OSBPL3 PEAK1

1.09e-084932111715368895
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CCT3 KIF1A MYCBP2 PFAS NUP205 DDX10 TTLL12 NF1 AP1B1 XPO5 UBR5 SYNE2 AFDN PHIP EXOSC10 CAD RIF1 TP53BP1

1.18e-076532111822586326
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MCMBP CCT3 KIF1A ITGAE NUP205 TTLL12 DIP2A ADAMTS9 DQX1 RECQL4 PKHD1 PLXNB3 CACNA1F WNT2B RNF213 LRRC40 MST1 MEGF6 FBN3

1.43e-077362111929676528
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 STAB1 SALL2 XPO5 UBR5 SYNE2 APAF1 CDC42BPB MEGF6 SLIT1 WDFY3

1.49e-072252111112168954
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SECISBP2L ENPP1 PFAS RAD54L2 TTLL12 DIP2A AP1B1 RECQL4 CARD6 AFDN ANKRD50 TARS2 ANKZF1 ACE2 SRRT PALS1 OSBPL3

5.55e-076502111738777146
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TRIM25 CCT3 MYCBP2 PFAS NUP205 DDX10 NF1 UBR5 RECQL4 AFDN PYCR3 PHIP TNS3 EXOSC10 CAD DDX49 RANBP9 LRRC40 SMTN SRRT CCT6A RIF1 SF3B3 WDFY3 TP53BP1

8.27e-0713532112529467282
Pubmed

Mammalian Rif1 contributes to replication stress survival and homology-directed repair.

RAD51 RIF1 TP53BP1

8.77e-074211319948482
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

TRIM25 CCT3 RAD54L2 RREB1 TTLL12 XPO5 EXOSC10 RNF213 SRRT CCT6A RIF1 TP53BP1

1.02e-063322111232786267
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PDE4B CCT3 MYCBP2 SH3BP1 NF1 AP1B1 UBR5 SYNE2 AFDN NLGN2 CAD KSR2 RANBP9 MSANTD2 GRM4 CDC42BPB PALS1 OSBPL3 WDFY3 TP53BP1

1.98e-069632112028671696
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MCMBP ATP6V0A1 HIVEP1 TRIM25 CCT3 KIF1A PFAS NUP205 DDX10 TTLL12 NF1 XPO5 AFDN PHIP NPAS2 CAD ATP13A1 HAT1 LRRC40 TARS2 SRRT CCT6A RIF1 SF3B3 PEAK1

2.09e-0614252112530948266
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYCBP2 NUP205 PKHD1 AFDN HS3ST1 CAD CDC42BPB SRRT SF3B3

4.40e-06202211924639526
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

PPP1R14D RREB1 STAB1 TRIM66 PYCR3 LRRC8E EXOSC10 CAD SRRT OSBPL3

1.00e-052832111018854154
Pubmed

The functional interactome landscape of the human histone deacetylase family.

CCT3 MYCBP2 RREB1 MTA3 UBR5 SYNE2 PHIP CAD CCT6A RIF1

1.20e-052892111023752268
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MCMBP ATP6V0A1 TRIM25 MYCBP2 TEX2 PFAS DDX10 TTLL12 DIP2A SACS UBR5 SYNE2 CCDC97 PYCR3 EXOSC10 CAD ATP13A1 APAF1 LRRC40 TARS2 CDC42BPB SF3B3 PEAK1 TP53BP1

1.36e-0514872112433957083
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TET2 HIVEP1 TRIM25 CCT3 MYCBP2 RAD54L2 RREB1 TTLL12 AURKA MTA3 AP1B1 XPO5 UBR5 EXOSC10 CAD DDX49 MSANTD2 HAT1 CCT6A TP53BP1

1.46e-0511032112034189442
Pubmed

The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1.

IKBKG PELI2 PELI1

1.80e-059211317997719
Pubmed

Pellino1 specifically binds to phospho-Thr18 of p53 and is recruited to sites of DNA damage.

PELI2 PELI1 TP53BP1

1.80e-059211330987826
Pubmed

WFS1 Spectrum Disorder

ENPP1 NEUROD1 MTNR1B PAX4

2.40e-0528211420301750
Pubmed

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.

SALL2 NF1 CCKAR SMTN THBS2 IGFBP2 PAX4

2.49e-05140211726930384
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DUSP28 MCMBP TRIM25 KIF1A PFAS NUP205 AURKA DNAAF5 AP1B1 XPO5 UBR5 AFDN PYCR3 TNS3 EXOSC10 RANBP9 ANKRD50 OSBPL3

3.10e-059742111828675297
Pubmed

Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling.

ALCAM L1CAM SLIT1

3.50e-0511211322399681
Pubmed

MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.

MST1 MST1L

3.66e-052211227609031
Pubmed

Homologous recombination resolution defect in werner syndrome.

RAD51 WRN

3.66e-052211212242278
Pubmed

Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein.

MST1 MST1L

3.66e-052211210728827
Pubmed

Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.

MST1 MST1L

3.66e-052211216961763
Pubmed

Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3.

BCL6 MTA3

3.66e-052211226460037
Pubmed

Beta-cell dysfunction in late-onset diabetic subjects carrying homozygous mutation in transcription factors NeuroD1 and Pax4.

NEUROD1 PAX4

3.66e-052211212200761
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB1 STAB2

3.66e-052211215572036
Pubmed

Cerebral ischemia-reperfusion is modulated by macrophage-stimulating 1 through the MAPK-ERK signaling pathway.

MST1 MST1L

3.66e-052211232017081
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB1 STAB2

3.66e-052211212077138
Pubmed

The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress.

RIF1 TP53BP1

3.66e-052211233141022
Pubmed

Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway.

MST1 MST1L

3.66e-052211229760744
Pubmed

Homozygosity mapping of a Weill-Marchesani syndrome locus to chromosome 19p13.3-p13.2.

ADAMTS10 FBN3

3.66e-052211211941487
Pubmed

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL).

BCL6 STAT6

3.66e-052211223852366
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB1 STAB2

3.66e-052211233008099
Pubmed

Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1.

RREB1 NEUROD1

3.66e-052211212482979
Pubmed

Mst1 deletion reduces hyperglycemia-mediated vascular dysfunction via attenuating mitochondrial fission and modulating the JNK signaling pathway.

MST1 MST1L

3.66e-052211231206688
Pubmed

Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule.

ALCAM L1CAM

3.66e-052211218483249
Pubmed

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

RIF1 TP53BP1

3.66e-052211223333305
Pubmed

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

STAB1 STAB2

3.66e-052211221293057
Pubmed

Overexpression of Aurora-A bypasses cytokinesis through phosphorylation of suppressed in lung cancer.

SECISBP2L AURKA

3.66e-052211231314582
Pubmed

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms.

BCL6 MTA3

3.66e-052211217545502
Pubmed

Sialylated keratan sulfates on MUC5B are Siglec-8 ligands in the human esophagus.

SIGLEC8 MUC5B

3.66e-052211239173029
Pubmed

53BP1 regulates DSB repair using Rif1 to control 5' end resection.

RIF1 TP53BP1

3.66e-052211223306437
Pubmed

BCL6 locus is hypermethylated in angioimmunoblastic T-cell lymphoma.

TET2 BCL6

3.66e-052211227921272
Pubmed

TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15.

ADAM15 TICAM1

3.66e-052211223365087
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB1 STAB2

3.66e-052211212473645
Pubmed

53BP1-RIF1: sculpting the DNA repair focus in 3D.

RIF1 TP53BP1

3.66e-052211231792447
Pubmed

Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.

MST1 MST1L

3.66e-05221128393443
Pubmed

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model.

MST1 MST1L

3.66e-052211224980820
Pubmed

Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching.

BCL6 STAT6

3.66e-052211210490661
Pubmed

Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping.

PELI2 PELI1

3.66e-052211211306823
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB1 STAB2

3.66e-052211221427291
Pubmed

Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice.

MST1 MST1L

3.66e-052211239253972
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB1 STAB2

3.66e-052211238946049
Pubmed

CRTH2-dependent, STAT6-independent induction of cedar pollen dermatitis.

STAT6 PTGDR2

3.66e-052211218477017
Pubmed

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.

MST1 MST1L

3.66e-052211224409221
Pubmed

Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.

MST1 MST1L

3.66e-05221128340069
Pubmed

Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.

MST1 MST1L

3.66e-05221129486989
Pubmed

Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice.

MST1 MST1L

3.66e-052211233887258
Pubmed

HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.

MST1 MST1L

3.66e-052211225938541
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB1 STAB2

3.66e-052211227977633
Pubmed

53BP1/RIF1 signaling promotes cell survival after multifractionated radiotherapy.

RIF1 TP53BP1

3.66e-052211231822909
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB1 STAB2

3.66e-052211233130055
Pubmed

Polymorphisms in Complement Factor H and Hemicentin-1 genes in a Japanese population with dry-type age-related macular degeneration.

CFH HMCN1

3.66e-052211217157600
Pubmed

SPEF2- and HYDIN-Mutant Cilia Lack the Central Pair-associated Protein SPEF2, Aiding Primary Ciliary Dyskinesia Diagnostics.

SPEF2 HYDIN

3.66e-052211231545650
Pubmed

Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes.

CFH HMCN1

3.66e-052211217591627
Pubmed

Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination.

BCL6 PELI1

3.66e-052211225295537
Pubmed

The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1.

HMGCR NF1

3.66e-052211216271875
Pubmed

RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation.

L1CAM RANBP9

3.66e-052211216000162
Pubmed

A novel isoform of the smooth muscle cell differentiation marker smoothelin.

SMTN INPP5J

3.66e-052211210023782
Pubmed

Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy.

MST1 MST1L

3.66e-052211230708325
Pubmed

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

STAB1 STAB2

3.66e-052211211829752
Pubmed

Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.

MST1 MST1L

3.66e-052211227696525
Pubmed

PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.

TNS3 PEAK1

3.66e-052211235687021
Pubmed

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

STAB1 STAB2

3.66e-052211237446152
Pubmed

Genomic analysis of mouse retinal development.

ABCA2 TRAPPC1 STAB1 AURKA NEUROD1 SALL2 SORCS2 NPAS2 WNT2B TACC2 GBA2 SEMA4G KLHL25 SLIT1 ZFYVE26 TRAF3IP3 WDFY3 NLK

4.70e-0510062111815226823
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

MCMBP TRIM25 CCT3 NSD3 NUP205 AURKA MTA3 XPO5 UBR5 EXOSC10 CAD THUMPD1 HAT1 RNF213 SRRT CCT6A RIF1 SF3B3

5.20e-0510142111832416067
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TET2 HIVEP1 MYCBP2 RREB1 SALL2 EIF4ENIF1 UBR5 PYCR3 RAD51 MSANTD2 IKBKG

5.50e-054182111134709266
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

ATP6V0A1 HIVEP1 PFAS BCL6 STAT6 AURKA DIP2A AP1B1 PLAGL1 RABGGTA BRWD1 ATP13A1 APAF1 TARS2 SMTN ADAMTS10 RIF1

5.53e-059252111728986522
Pubmed

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.

TRIM25 PFAS NUP205 ATP13A1 TARS2

5.58e-0567211529357390
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

CFH ENPP1 HMGCR BCL6 AURKA CCDC97 NOS2 RAD51 APAF1 WRN IGFBP2

5.87e-054212111119692168
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TRIM25 CCT3 MYCBP2 NUP205 DDX10 NF1 SACS UBR5 SYNE2 AFDN PHIP EXOSC10 CAD LRRC40 SRRT CCT6A RIF1 SF3B3

5.89e-0510242111824711643
Pubmed

An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.

SEMA4A PLXNB3 SEMA4G

6.02e-0513211324572910
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

CCT3 UBR5 ALDH1L2 EXOSC10 CAD CCT6A RIF1 SF3B3

6.62e-05221211829991511
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 MCMBP HIVEP1 MYCBP2 RASSF2 TEX2 NSD3 TTLL12 NF1 SYNE2 AFDN NR3C2 TNS3 SRRT OSBPL3 PEAK1

8.08e-058612111636931259
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

CCT3 AP1B1 XPO5 SRRT CCT6A RIF1

9.11e-05119211635776542
Pubmed

Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.

SEMA4A PLXNB3 SEMA4G

9.49e-0515211321122816
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KANSL1L HIVEP1 STAT6 FDX2 TNS3 ANKZF1 SHROOM2 RIF1

9.56e-05233211837704626
Pubmed

Nuclear structure in normal and Bloom syndrome cells.

RECQL4 WRN

1.09e-043211210779560
Pubmed

GENETIC RISK FACTORS IN SEVERE, NONSEVERE AND ACUTE PHENOTYPES OF CENTRAL SEROUS CHORIORETINOPATHY.

CFH NR3C2

1.09e-043211231815877
Pubmed

Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction.

MST1 MST1L

1.09e-043211217395874
Pubmed

Endothelial nitric oxide synthase (NOS3) knockout decreases NOS2 induction, limiting hyperoxygenation and conferring protection in the postischemic heart.

NOS2 IKBKG

1.09e-043211217114245
Pubmed

Inhibition of Th2 differentiation and GATA-3 expression by BCL-6.

BCL6 STAT6

1.09e-043211212594267
Pubmed

Androgen-receptor-interacting nuclear proteins.

RAD54L2 RNF17

1.09e-043211210961928
Pubmed

Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement.

MST1 MST1L

1.09e-043211227496379
Pubmed

Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function.

MST1 MST1L

1.09e-043211212606483
Pubmed

ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers.

ADAM15 ADAMTS10

1.09e-043211215358598
GeneFamilyPellino E3 ubiquitin protein ligases

PELI2 PELI1

1.63e-0431342676
GeneFamilyRecQ like helicases

RECQL4 WRN

5.37e-04513421049
CoexpressionGSE41867_MEMORY_VS_EXHAUSTED_CD8_TCELL_DAY30_LCMV_UP

IL12RB1 ARPP21 MYCBP2 ZSWIM2 ITGB5 FBXO4 CARD6 LRRC8E TTYH3 ZFYVE26

5.26e-0619921110M9480
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SPEF2 NCKAP5 EPB41L4A UBR5 SYNE2 AFDN BRWD1 RNF213 HMCN1

5.22e-072002129dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARPP21 NCKAP5 PNPLA1 SYNE2 PKHD1 SLC5A12 MST1 ZNF804B

2.19e-0617721282f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARPP21 NCKAP5 PNPLA1 SLC5A12 TTYH3 MST1 ACE2 ZNF804B

3.17e-061862128a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH STAB1 PLAGL1 SHROOM2 CERT1 CCT6A MEGF6 HMCN1

3.57e-061892128fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

CFH EPB41L4A MOV10L1 HS3ST1 PELI2 ANKRD50 SHROOM2 HMCN1

4.01e-061922128c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 SORCS2 PKHD1 NR3C2 L1CAM KSR2 OSBPL3 NLK

4.33e-06194212846070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS9 SORCS2 PKHD1 NR3C2 L1CAM KSR2 OSBPL3 NLK

4.33e-061942128abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 RASSF2 BCL6 STAB1 SEMA4A APAF1 PELI2 WDFY3

5.41e-0620021289e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KIF1A PFAS NR3C2 LRRC8E ZNF628 MUC5B

1.31e-0510821269c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KIF1A PFAS NR3C2 LRRC8E ZNF628 MUC5B

1.31e-05108212675d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

CFH RASGRP4 RASSF2 WNT2B HMCN1 PTCH2 TRAF3IP3

1.56e-051672127d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

ITGB5 STAB1 ALCAM HS3ST1 TTYH3 SLIT1 WDFY3

1.69e-0516921272c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

HLA-DQA2 NCKAP5 FFAR4 ALCAM TNS3 TTYH3 ZFYVE26

1.75e-0517021273a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCellCTRL-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

PDE4B RASSF2 BCL6 SYNE2 PELI2 PELI1 TRAF3IP3

1.75e-051702127151dabe1d240dde414c881bf4fa816c69fa1c32d
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 SH3BP1 CCDC97 IL17RC ZBTB42 HMCN1 WDFY3

1.82e-051712127e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCellfacs|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCMBP PDE4B SH3BP1 PFAS NSD3 FDX2 CCT6A

1.82e-051712127c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP5 STAB1 PLAGL1 PCDHB8 PALS1 HMCN1 PTCH2

1.89e-051722127f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP5 STAB1 PLAGL1 PCDHB8 PALS1 HMCN1 PTCH2

1.89e-0517221276ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellCTRL-Myeloid-Neutrophil|CTRL / Disease state, Lineage and Cell class

PDE4B RASSF2 BCL6 SYNE2 PELI2 PELI1 TRAF3IP3

1.89e-051722127ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCellASK440-Immune-Mast_cell|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

RASGRP4 RASSF2 SIGLEC8 HS3ST1 ATG9B TMEM44 TRAF3IP3

2.36e-051782127dcefc4afca3a40d1bd44722e66bca6b45a6c6c55
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HIVEP1 SORCS2 AFDN NLGN2 ALCAM LINC02693 PTGDR2

2.44e-051792127c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF2 SH3BP1 STAB1 FBXO4 NLGN2 PLXNB3 ZNF628

2.44e-0517921276eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASSF2 SH3BP1 STAB1 FBXO4 NLGN2 PLXNB3 ZNF628

2.44e-0517921272c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCellCiliated_cells-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

CADM4 ME3 HS3ST1 MSANTD2 MUC5B ZNF496 SEMA4G

2.44e-0517921271c41314b6fcfcac8d62034e7037570120d58f20f
ToppCell5'-Adult-SmallIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A CADM4 ARSI PLXNB3 L1CAM IGSF11 HMCN1

2.53e-0518021275e6e38ee0758ef2342a6a821c78ed24b57bb7b11
ToppCell5'-Adult-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A CADM4 ARSI PLXNB3 L1CAM IGSF11 HMCN1

2.53e-051802127b88cd7ae922782176c057342d1b9eb9b8e5e7204
ToppCell5'-Adult-SmallIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A CADM4 ARSI PLXNB3 L1CAM IGSF11 HMCN1

2.53e-051802127ebd6e719a03f25155fa8181be19469d04d6d10a6
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 ARPP21 ENPP1 RAD54L2 SACS PKHD1 IGFBP2

2.62e-05181212741969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 ARPP21 ENPP1 RAD54L2 SACS PKHD1 IGFBP2

2.62e-0518121273f50e61dc2a52d71a5801584617607e6246adcf2
ToppCellP03-Epithelial-airway_epithelial_cell-club_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPEF2 FFAR4 NOS2 ELMOD1 NHLRC4 CCKAR HYDIN

2.62e-05181212760a91587c59029a34e7bec1255083337fe21b72a
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BEND7 SORCS2 PKHD1 ALCAM GRM4 PALS1 IGFBP2

2.72e-051822127573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BEND7 SORCS2 PKHD1 ALCAM GRM4 PALS1 IGFBP2

2.72e-0518221276cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

PDE4B ADAM15 NOS2 STAB2 FAM13C ASB14 SHROOM2

2.72e-051822127fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TET2 PDE4B RASSF2 STAB1 AP1B1 TTYH3 STK40

2.91e-051842127d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 PNPLA1 SYNE2 SLC5A12 MST1 ACE2 ZNF804B

2.91e-0518421279434731f651820b05335085582960f08fbf895de
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM4 SIGLEC5 SORCS2 PLXNB3 L1CAM PCDHB8 IGSF11

2.91e-051842127a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 RREB1 PKHD1 SLC5A12 NPAS2 TTYH3 ZNF804B

3.12e-0518621275784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCelldroplet-Tongue-nan-24m-Epithelial-parabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM4 STAB1 AP1B1 AFDN ALCAM ACE2 SLIT1

3.12e-05186212718c06041c6c8a0ebac17b3c8aaebd67e652d315a
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS SYNE2 AFDN PLAGL1 CERT1 CCT6A HMCN1

3.12e-0518621270ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH ME3 TFPI2 WNT2B ADAMTS10 HYDIN PTGDR2

3.12e-051862127f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCelldroplet-Heart-HEART-1m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CADM4 SIGLEC5 EPB41L4A PLXNB3 L1CAM IGSF11 TFAP2B

3.34e-051882127921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH STAB1 PLAGL1 SHROOM2 CERT1 MEGF6 HMCN1

3.46e-0518921278e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellASK440-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

RASGRP4 RASSF2 SIGLEC8 HS3ST1 ATG9B TMEM44 TRAF3IP3

3.46e-05189212772a19b20cb0f7283afe5f85d62a21cff69fd78d0
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

CFH EPB41L4A ADAMTS9 PELI2 SHROOM2 HMCN1 ZNF804B

3.46e-05189212775c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L SORCS2 PKHD1 NR3C2 OSBPL3 WDFY3 NLK

3.46e-051892127830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 SYNE2 PKHD1 SLC5A12 NPAS2 TTYH3 ZNF804B

3.70e-0519121271c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 SYNE2 PKHD1 SLC5A12 NPAS2 TTYH3 ZNF804B

3.70e-0519121273c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

HIVEP1 UBR5 AFDN PLAGL1 PHIP WRN TCP11L2

3.82e-051922127916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

PDE4B RASSF2 STAB1 ALCAM TNS3 PELI1 TTYH3

3.82e-0519221277be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM15 SPEF2 EPB41L4A ME3 ADAMTS9 IGFBP2 HMCN1

3.82e-05192212781baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

PDE4B RASSF2 STAB1 TNS3 RNF213 PELI1 TTYH3

3.82e-051922127a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

PDE4B RASSF2 STAB1 ALCAM TNS3 PELI1 TTYH3

3.95e-05193212712bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

HIVEP1 UBR5 AFDN PLAGL1 PHIP WRN TCP11L2

3.95e-051932127e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellCOVID-19-Lymphoid-Tregs|Lymphoid / Condition, Lineage and Cell class

PDE4B NSD3 SYNE2 CARD6 RNF213 PELI1 TCP11L2

4.22e-0519521279ad844d9d5aac39d133ae8ab9c4839300f08064c
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALCAM SLC5A12 HS3ST1 ISYNA1 WNT2B PALS1 IGFBP2

4.36e-0519621278c8a73d9d9581b8d9a9babfa93459d12fb9eb3ac
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALCAM SLC5A12 HS3ST1 ISYNA1 WNT2B PALS1 IGFBP2

4.36e-051962127429de4119c8b2193c992d36a6af84f806730cbee
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

CCT3 AURKA XPO5 CAD CCT6A SF3B3 OSBPL3

4.79e-05199212785b3b1ad01368dae4adbc9da7efc148e49992f69
ToppCellTCGA-Colorectal-Primary_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

CCT3 AURKA XPO5 CAD CCT6A SF3B3 OSBPL3

4.79e-051992127c7d6a8398f2419b726a0461585d1ee0561654e3b
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 HLA-DQA2 NCKAP5 PLAGL1 ALCAM SEMA4A APAF1

4.95e-05200212786f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 ATP6V0A1 BCL6 STAB1 TTYH3 PTCH2 WDFY3

4.95e-052002127934c2efc780318c66d667ca75be0de350361d351
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-dn_T|Int-URO / Disease, condition lineage and cell class

WBP1 XPO5 UBR5 CAD C1GALT1C1 GSTCD ZFYVE26

4.95e-052002127020439d9e70fff7246650ab0e9105236688c3ec3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Neuron|5w / Sample Type, Dataset, Time_group, and Cell type.

EPB41L4A ME3 NEUROD1 ALCAM CDC42BPB TFAP2B PTCH2

4.95e-0520021276f3fe94107fa2a2ded4888780b36700cce48adb7
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TTC34 SYNE2 PLAGL1 NOS2 TFPI2 WNT2B

5.44e-0513921262fdc8f36510aff24abbc79ef2a842db75a85f946
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TTC34 SYNE2 PLAGL1 NOS2 TFPI2 WNT2B

5.44e-0513921265970a654c64e3b54f9d18c102f5b125eec892fc5
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R14D PKHD1 MUC5B GRM4 CCKAR ACE2

6.88e-0514521269b69bfdbf91ef197b4c483617aa67498d9d2cd79
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R14D PKHD1 MUC5B GRM4 CCKAR ACE2

6.88e-05145212631af9fce1dcd7e8ae1604476598e099232017ee9
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R14D PKHD1 MUC5B GRM4 CCKAR ACE2

6.88e-05145212676f0cde9acdc3ad5948c007dccf312665972c9e6
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono|bone_marrow / Manually curated celltypes from each tissue

RASGRP4 ATP6V0A1 ZSWIM2 STAB1 IGFBP2 WDFY3

7.70e-051482126de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RASSF2 SORCS2 NR3C2 ALCAM IGSF11 THBS2

8.00e-0514921265293c50b3fb41b1edaf9a97354899bd13770078c
ToppCellCOVID-19_Severe-multiplets|COVID-19_Severe / disease group, cell group and cell class

ENPP1 NCKAP5 DIP2A SYNE2 NPAS2 HYDIN

8.92e-051522126451745151322c2fcea22dbb3dba681e12634a510
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SPEF2 PPP1R14D NPHP4 FFAR4 CCNA1 ELMOD1

9.25e-051532126fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SPEF2 PPP1R14D NPHP4 FFAR4 CCNA1 ELMOD1

9.25e-0515321262482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nefm_(Striatum,_dSPNs,_neurofilament_state+)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZSWIM2 PPP1R14D NLRP14 PAX4

1.01e-045121241984936e6d7141b4ca6a2017af39aa41f9e7c959
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nefm_(Striatum,_dSPNs,_neurofilament_state+)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZSWIM2 PPP1R14D NLRP14 PAX4

1.01e-04512124e288e3551e75df98b901e0735bb9638fea81f82d
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ABCA2 ENPP1 DIP2A SYNE2 RNF213 OSBPL3

1.03e-041562126afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 BCL6 ITGAE FFAR4 SEMA4A MST1

1.14e-041592126807ee55fe0d3645fbfb98f641dd0a0555b847cf5
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 BCL6 ITGAE FFAR4 SEMA4A MST1

1.14e-0415921267bb76324d2026d4bd348126cb169c8411f0d7145
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR179 FFAR4 IGSF11 CCKAR MST1 ACE2

1.18e-04160212601ae730e9d0d05f3277f862f0c09bafb32b89db5
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR179 FFAR4 IGSF11 CCKAR MST1 ACE2

1.18e-0416021266de9e7be1d860d82d503bfbc779e72f072a6efc3
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR179 FFAR4 NEUROD1 TFPI2 GRM4 PAX4

1.18e-0416021266c89a2e4189e4f2b6b09b66c6aae6653785ab2f8
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR179 FFAR4 IGSF11 CCKAR MST1 ACE2

1.18e-041602126b4844a8c7755a2b2868019791d8d224154973445
ToppCelldroplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAE ARSI FFAR4 CRISP1 ISYNA1

1.35e-041642126a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM66 FBXO4 NLGN2 APAF1 IGSF11 ANKZF1

1.35e-041642126b895674ed2df87db8fbfb30b7e31620945588491
ToppCelldroplet-Tongue-nan-24m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA2 ENPP1 CADM4 NLGN2 ATG9B

1.40e-041042125a4ae3cae44aac8b6e0d14896f9acab44f0cc97c4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHP4 TRIM66 NPAS2 ATG9B GRM4 PTCH2

1.40e-0416521261b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHP4 TRIM66 NPAS2 ATG9B GRM4 PTCH2

1.40e-041652126b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_large-bowel / Manually curated celltypes from each tissue

KIF1A FFAR4 NOS2 PELI2 IGFBP2 INPP5J

1.45e-04166212613bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 ARSI PNPLA1 SLC5A12 IGSF11 ZNF804B

1.54e-041682126fa0d251693935116adf633d02b7ec4a295100865
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A CADM4 L1CAM IGSF11 ANKRD50 FBN3

1.54e-041682126948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR179 FFAR4 NEUROD1 TFPI2 GRM4 PAX4

1.54e-04168212617d46f993dc4ae22b8087808582aba77f5c61892
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FFAR4 ALCAM MUC5B IGSF11 CCKAR ACE2

1.59e-04169212608ac28c5ad8f5c5f9f54af341bf39e8f9417636e
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

HLA-DQA2 NCKAP5 STAB1 AP1B1 TTYH3 MEGF6

1.59e-041692126241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FFAR4 ALCAM MUC5B IGSF11 CCKAR ACE2

1.59e-041692126e5abd41db1e6724ad900e37658fa063b8e522908
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAM15 SEMA4A CACNA1F L1CAM C1GALT1C1

1.65e-041702126a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAM15 SEMA4A CACNA1F L1CAM C1GALT1C1

1.65e-041702126ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellhealthy_donor-Myeloid-Monocytic-Developing_Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

METAP1D AURKA DQX1 RECQL4 NLGN2 ASB14

1.65e-041702126cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ARPP21 SPEF2 NCKAP5 GPR179 CCNA1 HYDIN

1.65e-0417021268b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCellfacs|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH MCMBP SH3BP1 PFAS FDX2 CCT6A

1.75e-041722126a2d0a64ebf09d219a07d6bbad1056bad6d46b9be
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFH ATP6V0A1 RASSF2 STAB1 AP1B1 SEMA4A

1.75e-0417221269a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ME3 PKHD1 HMCN1 OSBPL3 MST1L INPP5J

1.81e-0417321260c74bdb40e635d906fd180412c23bf7fed61621e
DrugIodipamide [606-17-7]; Up 200; 3.6uM; MCF7; HT_HG-U133A

ADAM15 PPP1R14D ITGA2B SEMA4A SZT2 WNT2B TFAP2B CCKAR SRRT GSTCD PEAK1 PTGDR2

2.98e-07196210126490_UP
Diseaser-spondin-3 measurement

CFH C1RL MST1

1.13e-0572053EFO_0021878
Diseasesialic acid-binding Ig-like lectin 6 measurement

CFH SIGLEC8 SIGLEC5

1.80e-0582053EFO_0008285
DiseaseTYPE 2 DIABETES MELLITUS

ENPP1 NEUROD1 MTNR1B PAX4

4.06e-05282054125853
DiseaseType 2 diabetes mellitus

ENPP1 NEUROD1 MTNR1B PAX4

4.06e-05282054cv:C0011860
Diseasefree lanosterol measurement, free brassicasterol measurement

HMGCR CERT1

4.80e-0522052EFO_0020959, EFO_0020961
DiseasebolA-like protein 2 measurement

CFH HLA-DQA2

4.80e-0522052EFO_0802335
Diseasetensin-2 measurement

CFH MST1

1.43e-0432052EFO_0802122
DiseaseColorectal Carcinoma

TET2 RASSF2 AURKA NF1 SACS PKHD1 NR3C2 PHIP CAD TFPI2 WRN HAT1 SMTN TRAF3IP3

4.27e-0470220514C0009402
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

TDRD15 DDX10 KSR2

4.62e-04222053EFO_0009312
DiseaseX-23639 measurement

KIF1A PYCR3

4.74e-0452052EFO_0800853
Diseasevitronectin measurement

CFH NOS2 NLK

5.28e-04232053EFO_0021843
Diseasetotal lipids in medium VLDL

TDRD15 HMGCR CERT1 TP53BP1

5.45e-04542054EFO_0022153
Diseasepallidum volume change measurement, age at assessment

SORCS2 ELMOD1 SLIT1

6.79e-04252053EFO_0008007, EFO_0021494
Diseasecolon adenocarcinoma (is_marker_for)

TET2 PFAS NOS2

6.79e-04252053DOID:234 (is_marker_for)
Diseaseinflammatory bowel disease (implicated_via_orthology)

ANKZF1 MST1 MST1L

6.79e-04252053DOID:0050589 (implicated_via_orthology)
Diseasecoronary artery disease

TET2 TDRD15 KIF1A HMGCR TTC34 EPB41L4A ITGB5 PKHD1 CCDC97 ALCAM TNS3 KSR2 RNF213 LRRC40 ANKRD50 CERT1 TFAP2B CCT6A SF3B3

7.07e-04119420519EFO_0001645
Diseasegalectin-7 measurement

CFH MST1

7.07e-0462052EFO_0022034
DiseaseCholangitis, Sclerosing

NOS2 MST1

7.07e-0462052C0008313
Diseasethrombospondin-2 measurement

CFH THBS2

7.07e-0462052EFO_0008299
Diseaseinterleukin-23 receptor measurement

CFH MST1

7.07e-0462052EFO_0801725
Diseasephospholipids in VLDL measurement

TDRD15 HMGCR CERT1 TP53BP1

7.64e-04592054EFO_0022301
Diseasetotal lipids in VLDL measurement

TDRD15 HMGCR CERT1 TP53BP1

8.14e-04602054EFO_0022314
Diseasepancreatic ductal carcinoma (is_marker_for)

L1CAM MUC5B CCKAR ACE2

8.66e-04612054DOID:3587 (is_marker_for)
Diseasefree cholesterol in VLDL measurement

TDRD15 HMGCR CERT1 TP53BP1

8.66e-04612054EFO_0022276
DiseaseDiabetes Mellitus, Non-Insulin-Dependent

ENPP1 NEUROD1 ADAMTS9 NOS2 KSR2 MTNR1B PAX4

9.37e-042212057C0011860
Diseaseprimary biliary cholangitis (biomarker_via_orthology)

IL12RB1 NOS2 ACE2

9.52e-04282053DOID:12236 (biomarker_via_orthology)
Diseasepancreatic cancer (biomarker_via_orthology)

RAD51 CCKAR

9.86e-0472052DOID:1793 (biomarker_via_orthology)
DiseaseNephronophthisis, familial juvenile

NPHP4 ADAMTS9

9.86e-0472052C1855681
Diseaseclusterin measurement

CFH C1RL

9.86e-0472052EFO_0007655
Diseaseglycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement

SYNE2 GBA2

9.86e-0472052EFO_0800551
Diseasecholesterol in large VLDL measurement

TDRD15 HMGCR CERT1 TP53BP1

1.10e-03652054EFO_0021902
Diseasecholesterol in very large VLDL measurement

TDRD15 HMGCR CERT1 TP53BP1

1.10e-03652054EFO_0022230
Diseaselow density lipoprotein cholesterol measurement, physical activity

TDRD15 PFAS HMGCR CERT1

1.16e-03662054EFO_0003940, EFO_0004611
Diseasetype 2 diabetes mellitus (is_implicated_in)

ENPP1 HMGCR NEUROD1 NOS2 MTNR1B PAX4

1.29e-031712056DOID:9352 (is_implicated_in)
Diseasediabetes mellitus

MYCBP2 HLA-DQA2 RREB1 PAX4

1.30e-03682054EFO_0000400
DiseasePrimary sclerosing cholangitis

NOS2 MST1

1.31e-0382052C0566602
DiseaseCongenital Hand Deformities

L1CAM TFAP2B

1.31e-0382052C0018566
Diseasefree cholesterol change measurement, high density lipoprotein cholesterol measurement

FAM13C SLIT1

1.31e-0382052EFO_0004612, EFO_0020905
DiseaseMalignant neoplasm of breast

TICAM1 DDX10 AURKA NF1 BEND7 SYNE2 NOS2 RAD51 NPBWR1 TFPI2 TACC2 SHROOM2 MST1 RIF1 NLRP14 ZFYVE26 TP53BP1

1.43e-03107420517C0006142
Diseasesynaptotagmin-11 measurement

CFH RREB1

1.67e-0392052EFO_0802108
DiseaseKartagener Syndrome

SPEF2 DNAAF5 HYDIN

1.84e-03352053C0022521
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

SPEF2 DNAAF5 HYDIN

1.84e-03352053C4551906
DiseasePolynesian Bronchiectasis

SPEF2 DNAAF5 HYDIN

1.84e-03352053C4317124
Diseasedolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement

CFH SIGLEC5

2.08e-03102052EFO_0801544
Diseasevesicular integral-membrane protein VIP36 measurement

ITGB5 NLK

2.08e-03102052EFO_0022012
Diseasef-box/LRR-repeat protein 4 measurement

CFH C1RL

2.08e-03102052EFO_0802538
Disease3-methyl-2-oxobutyrate measurement

ANKRD50 NLK

2.08e-03102052EFO_0021020
DiseaseDrugs used in diabetes use measurement

MYCBP2 RREB1 NF1 KSR2 TFAP2B MTNR1B PAX4

2.12e-032552057EFO_0009924
Diseasereaction time measurement

TET2 NCKAP5 METAP1D EPB41L4A PKHD1 SLC5A12 FAM13C ATP13A1 TACC2 TFAP2B CCKAR PAX4

2.30e-0365820512EFO_0008393
Diseasecerebral cavernous malformation (implicated_via_orthology)

RNF213 CDC42BPB

2.54e-03112052DOID:0060669 (implicated_via_orthology)
Diseasesleep disorder (implicated_via_orthology)

NF1 TFAP2B

2.54e-03112052DOID:535 (implicated_via_orthology)
Diseaseschizophrenia, gastroesophageal reflux disease

PDE4B TSNARE1

2.54e-03112052EFO_0003948, MONDO_0005090
DiseaseInherited neuropathies

SACS L1CAM ZFYVE26

2.70e-03402053C0598589
DiseaseNight blindness, congenital stationary, type 1

GPR179 CACNA1F

3.03e-03122052C3501847
DiseaseNight Blindness, Congenital Stationary, Type 1A

GPR179 CACNA1F

3.03e-03122052C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

GPR179 CACNA1F

3.03e-03122052C1864877
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

GPR179 CACNA1F

3.03e-03122052C1850362
DiseaseX-Linked Csnb

GPR179 CACNA1F

3.03e-03122052C3711543
Diseasedementia (is_implicated_in)

HMGCR NOS2

3.03e-03122052DOID:1307 (is_implicated_in)
Diseaseanxiety disorder, stress-related disorder

PDE4B RAD51

3.03e-03122052EFO_0006788, EFO_0010098
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

GPR179 CACNA1F

3.03e-03122052C1848172
Diseasetriglycerides in large LDL measurement

TDRD15 SYNE2 TP53BP1

3.32e-03432053EFO_0022319
Diseasefree cholesterol to total lipids in very small VLDL percentage

HMGCR CERT1 TP53BP1

3.32e-03432053EFO_0022290
Diseasecognitive function measurement, self reported educational attainment

ARPP21 MYCBP2 STAB1 PKHD1 NPAS2 TSNARE1 WRN TFAP2B

3.53e-033552058EFO_0004784, EFO_0008354
Diseaseconcentration of large LDL particles measurement

TDRD15 HMGCR CERT1

3.55e-03442053EFO_0022160
Diseasecholesterol in medium VLDL measurement

TDRD15 HMGCR CERT1

3.55e-03442053EFO_0022225
DiseaseCone-rod synaptic disorder, congenital nonprogressive

GPR179 CACNA1F

3.56e-03132052C4041558
Diseasemiddle temporal gyrus volume measurement, Alzheimer's disease biomarker measurement

MYCBP2 KSR2

3.56e-03132052EFO_0006514, EFO_0010316
DiseaseSkin Abnormalities

AP1B1 APAF1

3.56e-03132052C0037268
Diseaseobesity (is_implicated_in)

ENPP1 FFAR4 CCKAR IGFBP2

3.78e-03912054DOID:9970 (is_implicated_in)
Diseasepulse pressure measurement

CFH TET2 TDRD15 TEX2 RREB1 ITGB5 NSD3 TRIM66 DIP2A TNS3 NPAS2 WNT2B RNF213 GRM4 CCT6A THBS2 SLIT1 MTNR1B HYDIN

4.00e-03139220519EFO_0005763
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

TDRD15 HMGCR FFAR4 SYNE2 TP53BP1

4.04e-031502055EFO_0004611, EFO_0020947
DiseaseMaturity onset diabetes mellitus in young

NEUROD1 PAX4

4.14e-03142052C0342276
DiseasePrimary Ciliary Dyskinesia

SPEF2 DNAAF5 HYDIN

4.28e-03472053C4551720
DiseaseOsteosarcoma

RECQL4 WRN GRM4

4.28e-03472053C0029463
DiseaseAdenocarcinoma of large intestine

AURKA UBR5 CDC42BPB STK40

4.57e-03962054C1319315
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

TDRD15 HMGCR FFAR4 SYNE2 CERT1 TP53BP1

4.70e-032222056EFO_0008317, EFO_0020943
Diseasephospholipids in medium LDL measurement

TDRD15 HMGCR CERT1

4.81e-03492053EFO_0022183
Diseasecomplement factor H-related protein 4 measurement

CFH KIF1A KSR2

4.81e-03492053EFO_0600091
Diseaseacute myeloid leukemia (is_marker_for)

TET2 NF1 CCNA1

4.81e-03492053DOID:9119 (is_marker_for)
Diseasecortical surface area measurement, neuroimaging measurement

RREB1 TTC34 ADAMTS9 ALCAM WNT2B MEGF6

5.23e-032272056EFO_0004346, EFO_0010736
Diseaseglucose measurement

TET2 PDE4B MYCBP2 RREB1 EPB41L4A NEUROD1 KCNK7 MTNR1B

5.29e-033802058EFO_0004468
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

TDRD15 HMGCR CERT1

5.39e-03512053EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Diseasephospholipids in very small VLDL measurement

HMGCR CERT1 TP53BP1

5.39e-03512053EFO_0022300
Diseasecholesterol to total lipids in small VLDL percentage

TDRD15 HMGCR KCNK7

5.39e-03512053EFO_0022242
DiseaseRolandic epilepsy

ALDH1L2 NR3C2

5.41e-03162052Orphanet_1945
DiseaseMonogenic diabetes

NEUROD1 PAX4

5.41e-03162052C3888631
Diseasepancreatic cancer (is_marker_for)

ADAM15 NOS2 APAF1 CCKAR

5.47e-031012054DOID:1793 (is_marker_for)
Diseasewaist-hip ratio

CFH TET2 ARPP21 MYCBP2 BCL6 RREB1 FFAR4 NUP205 STAB1 TRIM66 ADAMTS9 SYNE2 PHIP NPAS2 RAD51 TFAP2B ADAMTS10

5.47e-03122620517EFO_0004343
Diseasetotal lipids in LDL measurement

TDRD15 HMGCR CERT1

5.69e-03522053EFO_0022308
Diseasetriglycerides to total lipids in very large VLDL percentage

TDRD15 HMGCR KCNK7

6.00e-03532053EFO_0022340
Diseasefree cholesterol in small LDL measurement

TDRD15 HMGCR CERT1

6.00e-03532053EFO_0022271
DiseaseNight blindness, congenital stationary

GPR179 CACNA1F

6.10e-03172052C0339535
DiseaseMoyamoya Disease

NF1 RNF213

6.10e-03172052C0026654
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

HMGCR ADAMTS9 CCKAR PAX4

6.26e-031052054DOID:9352 (implicated_via_orthology)
DiseaseAcute Cerebrovascular Accidents

ITGA2B NOS2 WNT2B

6.32e-03542053C0751956
DiseaseOral ulcer

IL12RB1 HLA-DQA2 TICAM1 RREB1

6.69e-031072054HP_0000155
Diseasebipolar disorder, sex interaction measurement

TSNARE1 SLIT1

6.83e-03182052EFO_0008343, MONDO_0004985
DiseaseAge-related macular degeneration

CFH HMCN1

6.83e-03182052cv:C0242383
Diseasemigraine disorder, systolic blood pressure

ITGB5 RNF213

6.83e-03182052EFO_0006335, MONDO_0005277

Protein segments in the cluster

PeptideGeneStartEntry
CNNPRSVTLLIKGPN

CCT6A

366

P40227
NQCVLPPEIRGDLQQ

nan

356

A8MVM7
RNIPNGLQEFLDPLC

AFDN

946

P55196
GRQPFPNIVQLGLCE

APAF1

556

O14727
NPDVNPQLGISLQAC

ELMOD1

91

Q8N336
PLPVNSGQAQRVLCP

AURKA

36

O14965
PAAPLCLQTANTRGN

ADAM15

541

Q13444
IRPQQPNCLPLDQVT

ARSI

116

Q5FYB1
GPILLQRSCDVEPND

ALDH1L2

166

Q3SY69
GRSPQENLVPCDVLL

ATP13A1

326

Q9HD20
ELIHTINGNPALCPN

DEPDC4

206

Q8N2C3
SGQQLPRSICSLPCQ

GRM4

511

Q14833
EELCPTAGLPQRQID

FBXO4

201

Q9UKT5
LQALQEVCSRLPPEN

SH3BP1

381

Q9Y3L3
PGRENCKDEQLIPQL

BRWD3

606

Q6RI45
ELRIQPGNPSCTDLE

AP1B1

911

Q10567
AVQSLLQPGECERNP

ANKRD50

151

Q9ULJ7
LSAGALPNQDPVNCL

ASB14

376

A6NK59
LPNQDPVNCLQIALR

ASB14

381

A6NK59
TRPVLESPCVGNLND

CCDC144CP

1136

Q8IYA2
CNELPPRRNTEILTG

CFH

21

P08603
GLENETLFCLDQPRP

CCKAR

21

P32238
RPILNGQCIDSTPQD

RAD54L2

526

Q9Y4B4
EFQQLCAQRLPLLPG

FBN3

341

Q75N90
CAFLDQPRELGQPLQ

ATP4B

201

P51164
RLNSLLNIPEKCPEQ

C1GALT1C1

196

Q96EU7
ICRPGLVIGPQQQFL

CDC14C

316

A4D256
ALQAQSCLQGEPPAL

DUSP28

156

Q4G0W2
CNVTPPTPQNNLRLI

ARPP21

766

Q9UBL0
DSGLGLCLNNRPPRQ

ADAMTS10

446

Q9H324
GEVQRRLSPPECLNA

TFAP2B

251

Q92481
ESNPLERRLPNTFCG

CRISP1

86

P54107
LNQPCSGSVSLQPRR

GMCL1

436

Q96IK5
QPLGLECRAQAQPGV

MUC5B

2911

Q9HC84
QPLGLECRAQAQPGV

MUC5B

3611

Q9HC84
DAQPCQPVLINSSGL

MSANTD2

206

Q6P1R3
GNQLDPIQREPVCSA

RANBP9

666

Q96S59
PLIARILQGPCEQIS

RASSF2

241

P50749
GPQPISRLEQCGINA

RAD51

21

Q06609
IENILRACVGLPPQN

ISYNA1

486

Q9NPH2
VCPLEQLLQGINPRT

NUP205

876

Q92621
LQNGTLPCNDLVPRS

PCDHB1

566

Q9Y5F3
NGFDNTLSRPCRVPL

NPAS2

206

Q99743
PPEGNQEISRDNILC

CERT1

561

Q9Y5P4
CPGNQPALVQGILER

NOS2

776

P35228
QCLQRQGSCEDLPIP

CACNA1F

1806

O60840
GQPNTLICLVDNIFP

HLA-DQA2

126

P01906
ASLNILGNPQVPQEC

KANSL1L

436

A0AUZ9
LPCLQQDNNRPGILT

NR3C2

71

P08235
NNVLCHGIPDSRPLQ

METAP1D

156

Q6UB28
LPPALQSLQNCGEGV

MOV10L1

1176

Q9BXT6
CLAVLANPGQNILVP

TAT

151

P17735
GSRATQVCPQEDLRP

GPR179

1566

Q6PRD1
PTLRNGLEENFCRNP

MST1L

116

Q2TV78
EPRPNEECLQILGNA

HMGCR

441

P04035
LQAPQAPGLCRDEQS

LINC02693

101

A8MQB3
GSCENIPSQQRSPLL

KSR2

346

Q6VAB6
VVFQALEGPPACRLQ

KCNK7

26

Q9Y2U2
PLNCIGLAVAINPQE

MTNR1B

266

P49286
AASRLPVCSQQQGEP

CCDC97

71

Q96F63
CSLLGPDLRPQAQAN

ITGAE

126

P38570
LQENSRLGCQIVLTP

FDX2

146

Q6P4F2
PQRLPGADQEISICT

FFAR4

181

Q5NUL3
SQSLAQRCPLGENIP

PLXNB3

1631

Q9ULL4
QRCPLGENIPTLEDG

PLXNB3

1636

Q9ULL4
PPARTPCQQELDQVL

IGFBP2

221

P18065
CSGNLQLPPLSQRQS

PDE4B

46

Q07343
RGLQQLASCLLNPNP

PEAK1

1636

Q9H792
LQELVALQGQHPPCS

RASGRP4

386

Q8TDF6
IELALGNECPERSQP

PNPLA1

281

Q8N8W4
LPSEQGAPETLQRCL

IKBKG

41

Q9Y6K9
RLDCQVQGRPQPEVT

L1CAM

351

P32004
LVQCPFTRNPRDNLG

ENPP1

611

P22413
QENLSEAPCQQLLPR

LRRC8E

61

Q6NSJ5
RSQLPLEGLEQPACD

CDC42BPB

1696

Q9Y5S2
QPLGVACAPQGQLLV

NHLRC4

91

P0CG21
LEQQKGNRVPLCINP

NLK

486

Q9UBE8
LTVLREPECGNTPNA

ITGB5

706

P18084
QPLQNELSLGIGCPV

OOSP4A

46

A0A2R8YFL7
VLLLNPGPDRDATCN

PTGDR2

186

Q9Y5Y4
IPQEDCTGPNTLLRF

DQX1

131

Q8TE96
PRLQLVQLDEAGQPS

NPHP4

681

O75161
KIILNCQATGEPQPT

HMCN1

4456

Q96RW7
LQEDQGLPCTRLRSP

PAX4

131

O43316
PIILIGPQNCGQNEL

PALS1

481

Q8N3R9
IIACCNPVPPLVRQQ

EXOSC10

551

Q01780
LTVSDQRCDRLPQPG

ADAMTS9

911

Q9P2N4
CLLDLQVISPQPRNI

IGSF11

226

Q5DX21
SCQGIRPELELEPRQ

HYDIN

2926

Q4G0P3
IRQIIPPGFCTNTND

HAT1

111

O14929
ILQNDGVVTSPCARP

KLHL25

276

Q9H0H3
PIQEPGTQCELSQNL

CARD6

701

Q9BX69
LPGQNVTLTCRQITP

GBA2

241

Q9HCG7
LQNLQSRGPRDCVVL

ANKZF1

196

Q9H8Y5
CQILTRAPLGQDPPQ

CCNA1

66

P78396
CPTRGSVLLAQELPQ

C1RL

36

Q9NZP8
LVLTCAVTGNPRPNQ

CADM4

241

Q8NFZ8
NILPLVICSGVSNQP

DDX12P

676

Q92771
GLQPILCGNNRTIEP

ABCA2

411

Q9BZC7
DNPQECLLLEPGLNE

ACE2

136

Q9BYF1
IPEEQCQGRAPQLLL

ATG9B

576

Q674R7
DAGINLQPPLRTSCR

BRWD1

871

Q9NSI6
EVVENNLPLRSAPGC

BCL6

161

P41182
QPTQLELPEGCQGLA

IL12RB1

261

P42701
GGVNPQQCLPVLLDV

ME3

216

Q16798
VGTQNRQQPPISLIC

BEND7

191

Q8N7W2
QCRQLGLKQPTPVQL

DDX49

16

Q9Y6V7
ERINNINILVCTPGR

DDX10

186

Q13206
SNGNNLQLKDPTCRP

CUZD1

296

Q86UP6
VPTLRACLQPSQDPQ

DNAAF5

606

Q86Y56
PLIQGIDPSLQAENR

DIP2A

51

Q14689
PTLRNGLEENFCRNP

MST1

146

P26927
TRPVLESPCVGNLND

CCDC144A

1326

A2RUR9
NTQTPLRNLPGLCSD

HHIPL2

121

Q6UWX4
QDVLQGRLPCPVNTA

EPB41L4A

121

Q9HCS5
QRKPQQLISDCEGPS

SALL2

6

Q9Y467
QTRGRPCTQLQLLNP

SACS

726

Q9NZJ4
GDTIIIPCRLDVPQN

ALCAM

36

Q13740
ISRQELPPIVQNCCL

GSTCD

76

Q8NEC7
VRNATTLPPACPQNL

NLGN2

96

Q8NFZ4
TRGPQDNRSLCALEP

IL17RC

471

Q8NAC3
NNNTCSAVPPEGLLL

KIF1A

961

Q12756
NNDLLQIPPELGNCV

LRRC40

551

Q9H9A6
QIPPELGNCVNLRTL

LRRC40

556

Q9H9A6
AECGPQQELDLNSPR

MCMBP

106

Q9BTE3
PVELNEPLNTLQRLC

OSBPL3

546

Q9H4L5
DEQGRRQCVLVFPQP

NPBWR1

181

P48145
LRQEINAARPQCPVG

PELI1

271

Q96FA3
QLEAILGNCPRPTEA

PPP1R14D

111

Q9NXH3
LQNGSAPCTELVPRA

PCDHB8

566

Q9UN66
QLVPSRPAELGQQEL

HS3ST1

16

O14792
QELTLVGRRQPCVQA

MEGF6

51

O75095
TTFQPQNPLLGRACE

MTA3

366

Q9BTC8
PHQCGTIQLDFQLPL

TARS2

551

Q9BW92
QVLVQGCLLDPSQRE

SZT2

166

Q5T011
VLGPQQALSDRPCLV

SZT2

726

Q5T011
VDNLPPSNNCILGHI

SPEF2

521

Q9C093
LPHRLSCLGQQQQEP

PLAGL1

411

Q9UM63
LGNSPVPSIVQCLAR

STK40

41

Q8N2I9
PGGNRLRNQICEVLD

TCP11L2

146

Q8N4U5
LNTEQGPECSLRPNQ

SYNE2

4186

Q8WXH0
QIASACGNLFELPPR

TDRD15

106

B5MCY1
LSNEIRNIPRQAVPC

TDRD15

1626

B5MCY1
ELLPQGIACLQPRAA

NCKAP5

711

O14513
NNPPGLLNQTECVSD

RIF1

1326

Q5UIP0
RLNCPGGPAQLQALA

RECQL4

946

O94761
LAVCLAQQLPEDPGQ

RECQL4

966

O94761
EINAARPQCPVGLNT

PELI2

276

Q9HAT8
QQPAVLQPLASCPRL

RABGGTA

521

Q92696
PCSAQVIQILPQELG

PTCH2

571

Q9Y6C5
LLCTQPGQLPFNVIR

SEMA4A

291

Q9H3S1
VQLQCPLTPPRGLQV

SORCS2

771

Q96PQ0
EGQALRLLCDAPSNP

SIGLEC5

261

O15389
GQSLRLVCAVNSNPP

SIGLEC8

276

Q9NYZ4
GPRPCVQGDLQAAQL

SHROOM2

476

Q13796
QVCRNVLLDPQLVPG

CCT3

396

P49368
ECTERPSQLGQVFPL

SECISBP2L

146

Q93073
DVNSRGCPTLVQALP

MYCBP2

976

O75592
RNPQITCTGFDRPNL

WRN

721

Q14191
GLLTRNIQIQPDVSC

PKHD1

2951

P08F94
NLLCEQPTVPRENGK

FAM13C

361

Q8NE31
ILDIQPQGGLQCFPQ

ITGA2B

846

P08514
LVSRCPADNPGLVQA

TNS3

611

Q68CZ2
LRVLPNLPCVVQEGA

PYCR3

121

Q53H96
NLQNIRLRECELSPG

SRRT

481

Q9BXP5
ILQELLGQPVQRPAS

EIF4ENIF1

526

Q9NRA8
LPTEQPRLRVPGCNQ

ACD

126

Q96AP0
PRLRVPGCNQDLDVQ

ACD

131

Q96AP0
VLSCIPDNNQQPKGI

AKAP17A

546

Q02040
QLRNPPRLSVNCSEI

RNF17

281

Q9BXT8
GRCLSPNLQAQEAPA

INPP5J

381

Q15735
LPRGLQVGQPNLVVC

RNF213

1821

Q63HN8
ELNQSQQLPPRRQCG

TRAF3IP3

511

Q9Y228
KNPLCPLGQTVQSEL

TRAPPC1

111

Q9Y5R8
QLAPSGCNRQALPLS

ZNF804B

966

A4D1E1
PPRATQVDPCNLQEL

TSNARE1

246

Q96NA8
SCPQERLQQERPQLD

TSNARE1

326

Q96NA8
PRQEECSPQDNALGL

WDFY3

11

Q8IZQ1
RGDDVLLPCDQPSNL

SEMA4G

576

Q9NTN9
VPGRENCREEQLIPQ

PHIP

606

Q8WWQ0
SSPPALLIQQGSCEQ

SPATA12

106

Q7Z6I5
IQLQTLKCQLPQDPG

RREB1

391

Q92766
INNTVPLENSIPGNC

STAT6

341

P42226
NLTRQGSPDCVIPFL

TICAM1

476

Q8IUC6
LVAQQQCVGPLQTPL

PFAS

691

O15067
NELKQCIGRLQEPTP

TRIM25

346

Q14258
LVAALQTCRVQDPPG

TTTY10

26

Q9BZA0
SGNPIFRNPCTEQIL

XPO5

756

Q9HAV4
LCQDPNLLNPIHGIV

NF1

2671

P21359
TGPRCEVQLELQPVC

STAB1

2046

Q9NY15
PEQLPIDRCLQDNGQ

STAB2

2166

Q8WWQ8
IEPVQQAGCSATRLP

TMEM44

381

Q2T9K0
LILDQDQQGIPSCPG

TACC2

796

O95359
CGSISQVIEQLPQPN

TP53BP1

101

Q12888
GNICVVRLPPNTNDE

SF3B3

1051

Q15393
RPGVLLNQFPCENLL

TTLL12

351

Q14166
AEICNPRSVPLNIQG

NSD3

976

Q9BZ95
DGECPPQRSILEQLA

CAD

1371

P27708
VTQQQKLAPGRQLCP

nan

106

Q6Q795
NRLGILPSIPQCNFD

ZSWIM2

436

Q8NEG5
VLQTPLCSQRQPGAQ

ZBTB42

206

B2RXF5
LCSQRQPGAQPLVKD

ZBTB42

211

B2RXF5
EETLRGNPVLQLNPA

ATP6V0A1

491

Q93050
QDAQPITLAQCLGLP

ZNF496

166

Q96IT1
QEPTGNNAEICLLPL

TFPI2

26

P48307
GNITRIRLCNSPVPQ

THBS2

456

P35442
SEVLSQQRPCLGERP

ZSCAN29

636

Q8IWY8
EVQECRGTLAVNIPP

TEX2

1026

Q8IWB9
GEDIQPLLIRPVCNL

SLC5A12

531

Q1EHB4
IVTGNPRCQNPDFLR

SLIT1

691

O75093
RLGQQLTSQPVCIVP

TRIM66

401

O15016
CSGPENPELQILNEQ

TET2

171

Q6N021
FQNPRCENTPLIGRE

TTYH3

481

Q9C0H2
SLAQNSLCRQPGRAP

TTC34

496

A8MYJ7
PNLLRCGQDINPQRV

ZFYVE26

61

Q68DK2
ALRAPQQQLRELCPG

WBP1

16

Q96G27
CIPIGQIRVPGLQNL

HIVEP1

2466

P15822
AQPLAQLRSCPQEEG

SMTN

401

P53814
PRQLEPGLQGILITC

THUMPD1

36

Q9NXG2
ICDNIPGLVSRQRQL

WNT2B

71

Q93097
PNITVGTQVCLRNNP

UBR5

526

O95071
QTRLCVQEVETLPPG

ZNF628

946

Q5EBL2
PSLPNQAQLRRLCQV

NLRP14

416

Q86W24
GCLQLNPRTFLPEQN

NEUROD1

186

Q13562