Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

2.05e-052912GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

2.05e-052912GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

6.14e-053912GO:0043993
GeneOntologyCellularComponentsarcolemma

SGCD SCN1A KCNJ12 SLMAP KCNJ18 AGRN

1.83e-04190916GO:0042383
HumanPhenoImpulsivity

PODXL SCN1A CREBBP EP300 CDON DNMT1 FBXW11

1.45e-05149297HP:0100710
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

3.13e-052292HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

3.13e-052292HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

3.13e-052292HP:0001042
HumanPhenoKeloids

CREBBP EP300 NOTCH3

4.57e-0513293HP:0010562
HumanPhenoConfusion

NHLRC1 SCN1A CUBN NOTCH3 DNMT1

6.19e-0577295HP:0001289
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

9.36e-053292HP:0008752
HumanPhenoPhobia

CREBBP EP300

9.36e-053292HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

9.36e-053292HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

9.36e-053292HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

9.36e-053292HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

9.36e-053292HP:0005895
HumanPhenoApathy

PODXL SCN1A NOTCH3 CDON DNMT1

1.38e-0491295HP:0000741
HumanPhenoTrichiasis

CREBBP EP300

1.86e-044292HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

1.86e-044292HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

1.86e-044292HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

1.86e-044292HP:0006200
HumanPhenoVascular ring

CREBBP EP300

1.86e-044292HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

1.86e-044292HP:0031207
HumanPhenoPanic attack

PODXL RET CREBBP EP300

2.36e-0455294HP:0025269
HumanPhenoNon-epileptic seizure

PODXL RET CREBBP EP300

2.54e-0456294HP:0033052
HumanPhenoSleep apnea

GNE RET CREBBP AGRN EP300 NOTCH3

2.97e-04168296HP:0010535
HumanPhenoSleep-related breathing disorders

GNE RET CREBBP AGRN EP300 NOTCH3

3.07e-04169296HP:5200283
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

3.10e-045292HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

3.10e-045292HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

3.10e-045292HP:0030421
HumanPhenoAggressive behavior

PODXL SCN1A TRAPPC10 NBEA PRKCZ CREBBP EP300 CDON DNMT1 FBXW11

3.52e-045162910HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

PODXL SCN1A TRAPPC10 NBEA PRKCZ CREBBP EP300 CDON DNMT1 FBXW11

3.52e-045162910HP:0006919
HumanPhenoPhonophobia

SCN1A CREBBP EP300

3.95e-0426293HP:0002183
HumanPhenoNeoplasm of the central nervous system

PRKCZ RET CREBBP GDNF EP300 NOTCH3

4.06e-04178296HP:0100006
HumanPhenoLarge foramen magnum

CREBBP EP300

4.63e-046292HP:0002700
HumanPhenoAvascular necrosis of the capital femoral epiphysis

FN1 CREBBP EP300

6.08e-0430293HP:0005743
HumanPhenoDeviated nasal septum

CREBBP EP300

6.46e-047292HP:0004411
HumanPhenoNeoplasm of the nervous system

PRKCZ RET CREBBP GDNF EP300 NOTCH3

6.62e-04195296HP:0004375
HumanPhenoHypoplastic iliac wing

FN1 CREBBP EP300

6.70e-0431293HP:0002866
MousePhenoabnormal innervation pattern to muscle

UNC5C RET AGRN GDNF

1.88e-0533684MP:0001052
MousePhenoabnormal neural tube morphology

DNAAF2 FN1 GNE LAMC1 PKN2 RET CREBBP EP300 SFMBT2 AXIN2 CDON DNMT1

2.43e-055916812MP:0002151
MousePhenoabnormal skeletal muscle morphology

NHLRC1 MBNL2 SGCD MBNL1 LAMC1 RET AGRN GDNF EP300 MBNL3 NOTCH3

3.07e-055086811MP:0000759
MousePhenoincreased tail bud apoptosis

DNAAF2 FN1

6.97e-053682MP:0012277
MousePhenoabnormal nervous system development

DNAAF2 FN1 GNE UNC5C TRAPPC10 LAMC1 PKN2 RET MDK CREBBP AGRN EP300 SFMBT2 NOTCH3 AXIN2 CDON DNMT1

7.91e-0512576817MP:0003861
MousePhenofailure of initiation of embryo turning

DNAAF2 FN1 CUBN DNMT1

1.55e-0456684MP:0004180
MousePhenoabnormal renal glomerular capsule morphology

GNE PODXL LAMC1 RET GDNF

1.70e-04107685MP:0002828
MousePhenoabnormal embryo turning

DNAAF2 FN1 PKN2 CUBN EP300 SFMBT2 DNMT1

2.11e-04251687MP:0001700
MousePhenosingle kidney

LAMC1 RET BTBD1 GDNF

2.17e-0461684MP:0003604
DomainEGF_1

CLEC18A THBS4 FBLN2 FN1 CLEC18C LAMC1 ASTN2 ADAM33 C8B CUBN AGRN F12 NOTCH3 STAB1

1.97e-112559014PS00022
DomainEGF-like_CS

CLEC18A THBS4 FBLN2 FN1 CLEC18C LAMC1 ADAM33 C8B CUBN AGRN F12 NOTCH3 STAB1

3.63e-102619013IPR013032
DomainEGF_2

CLEC18A THBS4 FBLN2 CLEC18C LAMC1 ASTN2 ADAM33 C8B CUBN AGRN F12 NOTCH3 STAB1

4.38e-102659013PS01186
DomainEGF_3

CLEC18A THBS4 FBLN2 CLEC18C ASTN2 ADAM33 C8B CUBN AGRN F12 NOTCH3 STAB1

1.37e-092359012PS50026
DomainEGF-like_dom

CLEC18A THBS4 FBLN2 CLEC18C LAMC1 ADAM33 C8B CUBN AGRN F12 NOTCH3 STAB1

2.64e-092499012IPR000742
DomainEGF

CLEC18A THBS4 FBLN2 CLEC18C LAMC1 ADAM33 CUBN AGRN F12 NOTCH3 STAB1

1.72e-082359011SM00181
DomainEGF_CA

THBS4 FBLN2 CUBN AGRN F12 NOTCH3 STAB1

2.04e-06122907SM00179
DomainEGF-like_Ca-bd_dom

THBS4 FBLN2 CUBN AGRN F12 NOTCH3 STAB1

2.27e-06124907IPR001881
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

2.30e-052902IPR014744
DomainHAT_KAT11

CREBBP EP300

2.30e-052902PF08214
DomainKIX

CREBBP EP300

2.30e-052902PS50952
DomainZnF_TAZ

CREBBP EP300

2.30e-052902SM00551
DomainCBP_P300_HAT

CREBBP EP300

2.30e-052902IPR031162
DomainDUF902

CREBBP EP300

2.30e-052902PF06001
Domain-

CREBBP EP300

2.30e-0529021.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

2.30e-052902IPR010303
Domain-

CREBBP EP300

2.30e-0529021.10.1630.10
DomainCreb_binding

CREBBP EP300

2.30e-052902PF09030
Domain-

CREBBP EP300

2.30e-0529021.10.246.20
Domainzf-TAZ

CREBBP EP300

2.30e-052902PF02135
DomainZF_TAZ

CREBBP EP300

2.30e-052902PS50134
DomainK_chnl_inward-rec_Kir2.2

KCNJ12 KCNJ18

2.30e-052902IPR003272
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

2.30e-052902IPR013178
DomainKAT11

CREBBP EP300

2.30e-052902SM01250
DomainZnf_TAZ

CREBBP EP300

2.30e-052902IPR000197
DomainKIX_dom

CREBBP EP300

2.30e-052902IPR003101
DomainKIX

CREBBP EP300

2.30e-052902PF02172
DomainCBP_P300_HAT

CREBBP EP300

2.30e-052902PS51727
DomainEGF

THBS4 CUBN AGRN F12 NOTCH3 STAB1

3.28e-05126906PF00008
Domain-

CLEC18A CLEC18C CRISPLD1

4.72e-05159033.40.33.10
DomainCAP

CLEC18A CLEC18C CRISPLD1

4.72e-0515903PF00188
DomainCAP_domain

CLEC18A CLEC18C CRISPLD1

4.72e-0515903IPR014044
DomainSCP

CLEC18A CLEC18C CRISPLD1

4.72e-0515903SM00198
DomainAllrgn_V5/Tpx1

CLEC18A CLEC18C CRISPLD1

4.72e-0515903IPR001283
DomainK_chnl_inward-rec_Kir_N

KCNJ12 KCNJ18

6.87e-053902IPR013673
DomainIRK_N

KCNJ12 KCNJ18

6.87e-053902PF08466
DomainGrowth_fac_rcpt_

THBS4 FBLN2 LAMC1 CUBN NOTCH3 STAB1

1.08e-04156906IPR009030
DomainFN1_2

FN1 F12

1.37e-044902PS51091
Domainfn1

FN1 F12

1.37e-044902PF00039
DomainFibronectin_type1

FN1 F12

1.37e-044902IPR000083
DomainFN1

FN1 F12

1.37e-044902SM00058
DomainFN1_1

FN1 F12

1.37e-044902PS01253
DomainPHR

BTBD2 BTBD1

2.27e-045902PF08005
DomainChemokine-like_2FAM19A2

TAFA1 TAFA5

2.27e-045902PD298472
DomainPHR

BTBD2 BTBD1

2.27e-045902IPR012983
DomainChemokine-like_FAM19A2

TAFA1 TAFA5

2.27e-045902IPR020350
DomainTAFA

TAFA1 TAFA5

2.27e-045902PF12020
DomainTSP_1

CILP2 UNC5C C8B ADAMTSL3

2.42e-0463904PF00090
DomainTSP1

CILP2 UNC5C C8B ADAMTSL3

2.73e-0465904SM00209
DomainTSP1_rpt

CILP2 UNC5C C8B ADAMTSL3

2.73e-0465904IPR000884
DomainTSP1

CILP2 UNC5C C8B ADAMTSL3

2.73e-0465904PS50092
DomainIg_I-set

KIRREL3 CILP2 UNC5C ADAMTSL3 ALPK2 CDON

3.14e-04190906IPR013098
DomainI-set

KIRREL3 CILP2 UNC5C ADAMTSL3 ALPK2 CDON

3.14e-04190906PF07679
DomainNuc_rcpt_coact

CREBBP EP300

3.40e-046902IPR009110
DomainEGF_LAM_2

LAMC1 AGRN STAB1

4.00e-0430903PS50027
DomainEGF_LAM_1

LAMC1 AGRN STAB1

4.00e-0430903PS01248
Domain-

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

4.14e-0467990113.30.160.60
DomainBTB

ZBTB17 MYNN BTBD2 BTBD1 ZBTB1

4.29e-04131905PF00651
Domainzf-C2H2

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

4.91e-046939011PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

4.97e-046949011IPR013087
DomainLaminin_EGF

LAMC1 AGRN STAB1

6.33e-0435903PF00053
DomainEGF_Lam

LAMC1 AGRN STAB1

6.33e-0435903SM00180
DomainPkinase_C

RPS6KA4 PKN2 PRKCZ

7.47e-0437903IPR017892
DomainEGF_CA

THBS4 FBLN2 CUBN NOTCH3

7.92e-0486904PF07645
DomainLaminin_EGF

LAMC1 AGRN STAB1

8.08e-0438903IPR002049
Domain-

MBNL2 MBNL1 MBNL3

9.40e-04409034.10.1000.10
DomainIGc2

KIRREL3 CILP2 UNC5C ADAMTSL3 ALPK2 CDON

9.61e-04235906SM00408
DomainIg_sub2

KIRREL3 CILP2 UNC5C ADAMTSL3 ALPK2 CDON

9.61e-04235906IPR003598
DomainBTB

ZBTB17 MYNN BTBD2 BTBD1 ZBTB1

1.06e-03160905PS50097
DomainPkinase_C

RPS6KA4 PKN2 PRKCZ

1.08e-0342903PF00433
DomainMACPF

ASTN2 C8B

1.23e-0311902PF01823
DomainZINC_FINGER_C2H2_2

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

1.23e-037759011PS50157
DomainEGF_Ca-bd_CS

THBS4 FBLN2 CUBN NOTCH3

1.24e-0397904IPR018097
DomainZINC_FINGER_C2H2_1

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

1.25e-037779011PS00028
DomainEGF_CA

THBS4 FBLN2 CUBN NOTCH3

1.34e-0399904PS01187
DomainEGF_3

CUBN STAB1

1.47e-0312902PF12947
DomainMACPF

ASTN2 C8B

1.47e-0312902SM00457
DomainEGF_dom

CUBN STAB1

1.47e-0312902IPR024731
DomainMACPF

ASTN2 C8B

1.47e-0312902IPR020864
DomainZnf_C2H2-like

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

1.52e-037969011IPR015880
DomainZnF_C3H1

MBNL2 MBNL1 MBNL3

1.60e-0348903SM00356
DomainZnf_C2H2

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

1.66e-038059011IPR007087
Domainzf-CCCH

MBNL2 MBNL1 MBNL3

1.70e-0349903PF00642
DomainCUB

CUZD1 CUBN TMPRSS7

1.70e-0349903PF00431
DomainZnF_C2H2

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

1.71e-038089011SM00355
Domain-

FN1 F12

1.73e-03139022.10.10.10
DomainBTB

ZBTB17 MYNN BTBD2 BTBD1 ZBTB1

1.78e-03180905SM00225
DomainCUB

CUZD1 CUBN TMPRSS7

1.80e-0350903SM00042
DomainBTB/POZ_dom

ZBTB17 MYNN BTBD2 BTBD1 ZBTB1

2.01e-03185905IPR000210
DomainFN_type2_col-bd

FN1 F12

2.01e-0314902IPR000562
DomainFN2_2

FN1 F12

2.01e-0314902PS51092
Domainfn2

FN1 F12

2.01e-0314902PF00040
DomainFN2_1

FN1 F12

2.01e-0314902PS00023
DomainFN2

FN1 F12

2.01e-0314902SM00059
Domain-

CUZD1 CUBN TMPRSS7

2.02e-03529032.60.120.290
DomainCUB

CUZD1 CUBN TMPRSS7

2.13e-0353903PS01180
DomainSKP1/BTB/POZ

ZBTB17 MYNN BTBD2 BTBD1 ZBTB1

2.21e-03189905IPR011333
Domain-

TMPRSS7 AGRN

2.31e-03159023.30.70.960
DomainAGC-kinase_C

RPS6KA4 PKN2 PRKCZ

2.49e-0356903IPR000961
DomainAGC_KINASE_CTER

RPS6KA4 PKN2 PRKCZ

2.49e-0356903PS51285
PathwayPID_NFAT_3PATHWAY

PRKCZ NR4A1 CREBBP EP300

8.45e-0553624M113
PathwayREACTOME_SIGNALING_BY_NOTCH

AGO3 NBEA MDK ATP2A3 CREBBP EP300 NOTCH3

9.83e-05246627M10189
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300 DNMT1

1.02e-0421623M39593
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

AGO3 ATP2A3 CREBBP EP300 NOTCH3

1.74e-04119625M607
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300 NOTCH3

1.74e-0425623M27880
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.89e-045622MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

1.89e-045622M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

1.89e-045622M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

1.89e-045622M27228
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

FN1 ESPL1 CREBBP EP300

2.37e-0469624M48052
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.82e-046622M22062
PathwayREACTOME_SIGNALING_BY_ALK

MDK EP300 DNMT1

3.02e-0430623M42517
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

3.94e-047622MM1573
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4

AGO3 RET CREBBP

4.40e-0434623M46422
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

ZBTB17 LAMC1 CREBBP EP300

4.59e-0482624M2
PathwayKEGG_ECM_RECEPTOR_INTERACTION

THBS4 FN1 LAMC1 AGRN

5.03e-0484624M7098
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

5.24e-048622M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

5.24e-048622M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

5.24e-048622M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

5.24e-048622M46443
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

6.72e-049622M47451
PathwayREACTOME_DISEASES_OF_METABOLISM

NHLRC1 GNE CUBN ADAMTSL3 AGRN NOTCH3

7.85e-04250626M27554
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

8.37e-0410622M27945
PathwayWP_WNT_SIGNALING_AND_PLURIPOTENCY

PRKCZ CREBBP EP300 AXIN2

1.01e-03101624M39387
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

PRKCZ CREBBP EP300 AXIN2

1.01e-03101624MM15829
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.02e-0311622MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

1.02e-0311622M48021
PathwayREACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING

EP300 DNMT1

1.02e-0311622M42523
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

1.02e-0311622M26924
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

CREBBP EP300 NOTCH3

1.14e-0347623M7946
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NBEA CREBBP EP300

1.22e-0348623M611
PathwayPID_AJDISS_2PATHWAY

RET CREBBP GDNF

1.22e-0348623M142
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.22e-0312622M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

1.22e-0312622M27765
PathwayREACTOME_SIGNALING_BY_NOTCH3

CREBBP EP300 NOTCH3

1.29e-0349623M618
PathwayWP_TROP2_REGULATORY_SIGNALING

FN1 MDK TACSTD2

1.29e-0349623M46458
PathwayWP_CANCER_PATHWAYS

ZBTB17 FN1 LAMC1 RET CREBBP EP300 NOTCH3 AXIN2

1.62e-03507628M48302
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

1.67e-0314622M27808
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.93e-0315622MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

1.93e-0315622M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

1.93e-0315622MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

1.93e-0315622M953
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

2.20e-0316622M27121
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

2.20e-0316622M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

2.20e-0316622MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

2.20e-0316622M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

2.20e-0316622M27940
PathwayKEGG_CELL_CYCLE

ZBTB17 ESPL1 CREBBP EP300

2.21e-03125624M7963
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

FN1 LAMC1 AGRN

2.21e-0359623M27218
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

2.48e-0317622MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

2.48e-0317622M48025
PathwayREACTOME_SIGNALING_BY_ALK

MDK EP300

2.48e-0317622MM14790
Pubmed

Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood.

MBNL2 MBNL1 MBNL3

1.79e-08392332332745
Pubmed

Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle.

MBNL2 MBNL1 MBNL3

1.79e-08392319095965
Pubmed

Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells.

MBNL2 MBNL1 MBNL3

1.79e-08392311929853
Pubmed

Muscleblind proteins regulate alternative splicing.

MBNL2 MBNL1 MBNL3

1.79e-08392315257297
Pubmed

Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy.

MBNL2 MBNL1 MBNL3

1.79e-08392328698297
Pubmed

Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.

MBNL2 MBNL1 MBNL3

1.79e-08392325263597
Pubmed

Muscleblind-Like 1 and Muscleblind-Like 3 Depletion Synergistically Enhances Myotonia by Altering Clc-1 RNA Translation.

MBNL2 MBNL1 MBNL3

7.15e-08492326501102
Pubmed

Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3.

MBNL2 MBNL1 MBNL3

7.15e-08492312915312
Pubmed

Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.

PRKCZ RET GDNF AXIN2

8.14e-081692418177851
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ANKRD36B AGO3 SLMAP NBEA ZNF317 SFMBT2

3.01e-0710192610997877
Pubmed

MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1.

MBNL2 MBNL1 MBNL3

3.56e-07692319720736
Pubmed

Renal collecting system growth and function depend upon embryonic γ1 laminin expression.

LAMC1 RET AGRN GDNF

3.91e-072392421903675
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

FBLN2 FN1 LAMC1 AGRN CDON

7.82e-076492522261194
Pubmed

Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS.

KCNJ12 KCNJ18 GDNF

9.94e-07892327930290
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

FN1 LAMC1 AGRN GDNF

1.04e-062992422613833
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

FN1 LAMC1 AGRN NOTCH3

1.37e-063192411431694
Pubmed

Kidney development in the absence of Gdnf and Spry1 requires Fgf10.

PODXL RET GDNF

1.49e-06992320084103
Pubmed

The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts.

CREBBP EP300 DNMT1

1.49e-06992318241125
Pubmed

Search for cellular partners of human papillomavirus type 16 E2 protein.

BTBD2 BTBD1 NR4A1

1.49e-06992318305892
Pubmed

Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3.

RET GDNF AXIN2

1.49e-06992321523854
Pubmed

Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos.

PODXL RET GDNF

2.12e-061092321552539
Pubmed

Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.

PODXL RET CUBN GDNF

2.83e-063792416319116
Pubmed

Lrp4 regulates initiation of ureteric budding and is crucial for kidney formation--a mouse model for Cenani-Lenz syndrome.

RET GDNF AXIN2

2.91e-061192320454682
Pubmed

Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.

MBNL2 MBNL1 MBNL3

3.87e-061292337143315
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

FBLN2 LAMC1 AGRN

5.03e-061392312682087
Pubmed

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.

PRKCZ RET GDNF

5.03e-061392327597235
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

FN1 LAMC1 PRKCZ RET NR4A1 CREBBP F12 FBXW11

6.64e-0637192825241761
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

6.92e-06292227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

6.92e-06292234845315
Pubmed

Compound loss of muscleblind-like function in myotonic dystrophy.

MBNL2 MBNL1

6.92e-06292224293317
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

6.92e-06292219729597
Pubmed

Functional RET G691S polymorphism in cutaneous malignant melanoma.

RET GDNF

6.92e-06292219561646
Pubmed

RET and GDNF mutations are rare in fetuses with renal agenesis or other severe kidney development defects.

RET GDNF

6.92e-06292221490379
Pubmed

Expression Analysis of GDNF/RET Signaling Pathway in Human AD-MSCs Grown in HEK 293 Conditioned Medium (HEK293-CM).

RET GDNF

6.92e-06292232803668
Pubmed

GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling.

RET GDNF

6.92e-06292224143282
Pubmed

Optical Mapping Approaches on Muscleblind-Like Compound Knockout Mice for Understanding Mechanistic Insights Into Ventricular Arrhythmias in Myotonic Dystrophy.

MBNL2 MBNL1

6.92e-06292228416514
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

6.92e-06292239287984
Pubmed

Vitamin D regulation of GDNF/Ret signaling in dopaminergic neurons.

RET GDNF

6.92e-06292229018141
Pubmed

The in vivo response of stem and other undifferentiated spermatogonia to the reversible inhibition of glial cell line-derived neurotrophic factor signaling in the adult.

RET GDNF

6.92e-06292222232066
Pubmed

Increased Muscleblind levels by chloroquine treatment improve myotonic dystrophy type 1 phenotypes in in vitro and in vivo models.

MBNL2 MBNL1

6.92e-06292231754023
Pubmed

Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy.

MBNL2 MBNL1

6.92e-06292229331264
Pubmed

Mbnl1 and Mbnl2 regulate brain structural integrity in mice.

MBNL2 MBNL1

6.92e-06292234848815
Pubmed

Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis.

FN1 STAB1

6.92e-06292234968453
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

6.92e-06292220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

6.92e-06292225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

6.92e-06292211559821
Pubmed

Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes.

NR4A1 DNMT1

6.92e-06292227322146
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

6.92e-06292232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

6.92e-06292219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

6.92e-06292224522976
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

6.92e-06292221847097
Pubmed

Protein kinase A regulates GDNF/RET-dependent but not GDNF/Ret-independent ureteric bud outgrowth from the Wolffian duct.

RET GDNF

6.92e-06292220816800
Pubmed

High expression of the RET receptor tyrosine kinase and its ligand GDNF identifies a high-risk subset of estrogen receptor positive breast cancer.

RET GDNF

6.92e-06292237061618
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

6.92e-06292234813504
Pubmed

RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association.

RET GDNF

6.92e-06292225242331
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

6.92e-06292220301699
Pubmed

Modulation of the tyrosine kinase receptor Ret/glial cell-derived neurotrophic factor (GDNF) signaling: a new player in reproduction induced anterior pituitary plasticity?

RET GDNF

6.92e-06292221239429
Pubmed

GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors.

RET GDNF

6.92e-06292223650283
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

6.92e-06292224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

6.92e-06292237816914
Pubmed

Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse.

KCNJ12 KCNJ18

6.92e-06292215705530
Pubmed

High glucose promotes cell proliferation and enhances GDNF and RET expression in pancreatic cancer cells.

RET GDNF

6.92e-06292220960036
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

6.92e-06292211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

6.92e-06292210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

6.92e-06292235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

6.92e-06292231898871
Pubmed

Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice.

RET GDNF

6.92e-06292211774071
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

6.92e-06292230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

6.92e-06292227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

6.92e-06292219272189
Pubmed

Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins.

MBNL2 MBNL1

6.92e-06292222901804
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

6.92e-06292232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

6.92e-06292230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

6.92e-06292221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

6.92e-0629229811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

6.92e-06292224089570
Pubmed

GDNF restores human blood-nerve barrier function via RET tyrosine kinase-mediated cytoskeletal reorganization.

RET GDNF

6.92e-06292222326552
Pubmed

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.

MBNL1 MBNL3

6.92e-06292210970838
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

6.92e-06292215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

6.92e-06292239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

6.92e-06292222303793
Pubmed

Conserved developmental alternative splicing of muscleblind-like (MBNL) transcripts regulates MBNL localization and activity.

MBNL2 MBNL1

6.92e-06292220009516
Pubmed

Mutations of the RET-GDNF signaling pathway in Ondine's curse.

RET GDNF

6.92e-0629229497256
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

6.92e-06292234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

6.92e-06292234019788
Pubmed

Distal Alternative Last Exons Localize mRNAs to Neural Projections.

MBNL2 MBNL1

6.92e-06292226907613
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

6.92e-06292215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

6.92e-06292229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

6.92e-06292224551300
Pubmed

The aPKC-CBP Pathway Regulates Post-stroke Neurovascular Remodeling and Functional Recovery.

PRKCZ CREBBP

6.92e-06292229173896
Pubmed

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain.

MBNL2 MBNL1

6.92e-06292226257173
Pubmed

Acute stress disrupts intestinal homeostasis via GDNF-RET.

RET GDNF

6.92e-06292232808420
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

6.92e-06292233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

6.92e-0629229018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

6.92e-06292224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

6.92e-06292230135524
Pubmed

Opposing roles of miR-294 and MBNL1/2 in shaping the gene regulatory network of embryonic stem cells.

MBNL2 MBNL1

6.92e-06292229735517
Pubmed

Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.

RET GDNF

6.92e-06292227607574
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

6.92e-06292216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

6.92e-06292229217654
InteractionCAMKV interactions

DNAAF2 ZRANB2 LAMC1 PKN2 MDK AGRN

1.58e-05118916int:CAMKV
InteractionZNF8 interactions

FBLN2 ZBTB17 PKN2 MYNN ZFP62

1.61e-0570915int:ZNF8
InteractionSCGB1A1 interactions

FN1 CUBN AGRN

1.90e-0512913int:SCGB1A1
InteractionZBTB17 interactions

ZBTB17 MYNN CREBBP EP300 ZFP62

2.57e-0577915int:ZBTB17
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZBTB17 ZNF792 MZF1 ZNF689 ZNF589 ZKSCAN7 MYNN ZNF225 ZNF317 ZBTB1 ZFP62

4.54e-05718651128
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB17 MYNN BTBD2 BTBD1 ZBTB1

1.20e-04134655861
GeneFamilyZinc fingers CCCH-type

MBNL2 MBNL1 MBNL3

2.67e-043565373
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

KIRREL3 UNC5C ADAMTSL3 ALPK2 CDON

2.82e-04161655593
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ12 KCNJ18

1.48e-0316652276
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.67e-0317652486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.88e-031865291
GeneFamilyImmunoglobulin like domain containing

KIRREL3 CILP2 ADAMTSL3 CDON

5.13e-03193654594
CoexpressionNABA_ECM_GLYCOPROTEINS

CILP2 THBS4 FBLN2 FN1 LAMC1 AGRN CRISPLD1

5.08e-06191927MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

CILP2 THBS4 FBLN2 FN1 LAMC1 AGRN CRISPLD1

6.01e-06196927M3008
CoexpressionNABA_MATRISOME

CLEC18A CILP2 THBS4 FBLN2 FN1 CLEC18C LAMC1 ADAM33 MDK ADAMTSL3 AGRN CRISPLD1 GDNF F12

1.09e-0510089214MM17056
CoexpressionNABA_MATRISOME

CLEC18A CILP2 THBS4 FBLN2 FN1 CLEC18C LAMC1 ADAM33 MDK ADAMTSL3 AGRN CRISPLD1 GDNF F12

1.33e-0510269214M5889
CoexpressionAMIT_EGF_RESPONSE_40_HELA

MBNL2 KCNJ12 MBNL1 NR4A1

1.44e-0542924M4204
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

FBLN2 SPINK1 MBNL2 LAMC1 NR4A1 SFMBT2

2.68e-05166926M1542
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

FBLN2 SPINK1 MBNL2 LAMC1 NR4A1 SFMBT2

4.09e-05179926MM660
CoexpressionNABA_CORE_MATRISOME

CILP2 THBS4 FBLN2 FN1 LAMC1 AGRN CRISPLD1

4.73e-05270927MM17057
CoexpressionNABA_CORE_MATRISOME

CILP2 THBS4 FBLN2 FN1 LAMC1 AGRN CRISPLD1

5.31e-05275927M5884
CoexpressionGSE30153_LUPUS_VS_HEALTHY_DONOR_BCELL_DN

SPINK1 MBNL2 BTBD2 RET CUBN STAB1

7.16e-05198926M8424
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 GNE TTLL6 TSPAN13 NR4A1 ATP2A3

1.16e-07185927fd1911b57927c03470f9387962ca9581e5643fb3
ToppCellfacs-Large_Intestine-Distal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 GNE TTLL6 TSPAN13 NR4A1 ATP2A3

1.16e-071859277a18d525de6f874924bfc61b9666b307da86421a
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

CLEC18A CILP2 FN1 SGCD UNC5C ADAMTSL3 CRISPLD1

1.29e-071889277b1e3f8a941eaa68e89c562129a92314642eec66
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FBLN2 SGCD UNC5C ADAM33 NR4A1 ADAMTSL3 CDON

1.60e-07194927439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellMesenchymal_cells-Fibro/Chondro_p.|Mesenchymal_cells / Lineage and Cell class

CILP2 THBS4 FN1 TSPAN13 PRKCZ TAFA5 CRISPLD1

1.65e-07195927b95a631d54c6cf85e48e1e638703206aaaebc073
ToppCell(3)_Chondrocytes-(34)_Chondro-progen|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CILP2 THBS4 TSPAN13 PRKCZ TAFA5 CRISPLD1 CDON

1.65e-07195927d00cb2fab25f2026a9668a7f0686938a2e7155e2
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

FBLN2 FN1 SGCD UNC5C LAMC1 ADAM33 ADAMTSL3

1.84e-0719892726e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RPS6KA4 SCN1A TAFA1 TMPRSS7 ESPL1 STAB1

1.18e-061649264307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RPS6KA4 SCN1A TAFA1 TMPRSS7 ESPL1 STAB1

1.18e-061649261d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

FBLN2 KCNJ12 UNC5C CUZD1 RET NOTCH3

1.35e-06168926b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

FBLN2 KCNJ12 UNC5C CUZD1 RET NOTCH3

1.35e-06168926838ce47d4958ba12047882f97925eddd02f081c7
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PODXL KCNJ12 TSPAN13 ATP2A3 AGRN STAB1

1.66e-06174926b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITPKC RPS6KA4 GNE NR4A1 TACSTD2 NOTCH3

1.66e-06174926207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLEC18A CILP2 SGCD CLEC18C ADAMTSL3 CRISPLD1

2.37e-061859268ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIRREL3 FBLN2 FN1 UNC5C LAMC1 ADAMTSL3

2.37e-061859268f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLEC18A CILP2 SGCD CLEC18C ADAMTSL3 CRISPLD1

2.37e-06185926b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

NBEA CUBN MDK NOTCH3 CDON GAREM1

2.52e-06187926ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

KIRREL3 FBLN2 FN1 UNC5C LAMC1 ADAM33

2.52e-061879264ea486991f66c29728d127171a07b81404ec0b78
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD36B FBLN2 FN1 PODXL MDK ATP2A3

2.60e-06188926a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THBS4 FBLN2 SGCD ADAM33 CCDC89 CDON

2.60e-061889260e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

THBS4 FN1 SGCD ADAM33 TAFA5 CDON

2.68e-06189926c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCellfacs-Large_Intestine-Distal|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 TTLL6 TSPAN13 NR4A1 ATP2A3

2.76e-061909263964a8390522b61b73235151bb0a2ff36b856867
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FBLN2 SGCD UNC5C ADAM33 ADAMTSL3 CDON

3.03e-061939269ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 FN1 UNC5C TSPAN13 TAFA5 CRISPLD1

3.40e-061979266e111ba16fc8adde782b3f7da250248cddf11228
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FBLN2 FN1 SGCD UNC5C MDK NOTCH3

3.51e-06198926bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

CILP2 THBS4 FN1 TSPAN13 CRISPLD1 CDON

3.51e-061989269f9dcf23ffb333105263132d87b90095642294cf
ToppCell(2)_Fibroblasts|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CILP2 THBS4 FBLN2 FN1 MBNL1 CDON

3.61e-06199926777423b413376b0d3fbd92ff51dd0133fb54d293
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial|6m / Sample Type, Dataset, Time_group, and Cell type.

FN1 SGCD LAMC1 MAFF NR4A1 MDK

3.71e-062009262cc98abf11f5b58707de45a2282f03d47f00f035
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 FN1 TSPAN13 MDK ADAMTSL3 CRISPLD1

3.71e-06200926be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC18A FN1 UNC5C CLEC18C TAFA5 CRISPLD1

3.71e-06200926b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC18A FN1 UNC5C CLEC18C TAFA5 CRISPLD1

3.71e-06200926f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 FN1 TSPAN13 MDK ADAMTSL3 CRISPLD1

3.71e-06200926d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 FN1 TSPAN13 MDK ADAMTSL3 CRISPLD1

3.71e-062009268e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-4|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

THBS4 FBLN2 FN1 SGCD ADAM33 TAFA5

3.71e-0620092654b18c92daaa3b3368c0c46134b0c27e10c8dbb0
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FBLN2 SGCD LAMC1 ADAM33 NR4A1 ADAMTSL3

3.71e-0620092644317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC18A CILP2 FN1 UNC5C ADAMTSL3 CRISPLD1

3.71e-06200926b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

FN1 SGCD LAMC1 MAFF NR4A1 MDK

3.71e-062009260f7431f670f3a175377cefae3479403a881bb8fb
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP2 FN1 TSPAN13 MDK ADAMTSL3 CRISPLD1

3.71e-06200926c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCellcellseq2-Mesenchymal-Fibroblastic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FBLN2 SGCD LAMC1 ADAM33 NR4A1 ADAMTSL3

3.71e-062009261c10597edd532bf172ca09870a937d35e2585081
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FBLN2 SGCD LAMC1 ADAM33 NR4A1 ADAMTSL3

3.71e-06200926440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC18A CILP2 FN1 UNC5C ADAMTSL3 CRISPLD1

3.71e-062009267c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 TSPAN13 CRISPLD1 GDNF NOTCH3

1.60e-05152925d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 TSPAN13 CRISPLD1 GDNF NOTCH3

1.60e-05152925d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SPINK1 NR4A1 MDK TACSTD2 NOTCH3

1.99e-05159925a7bcff268b1962a561fd2848e01ae16565bce895
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

UNC5C MDK TACSTD2 GDNF NOTCH3

2.30e-051649258d1d0424943d3e98c8b6399dbf702e0035d0db7b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN2 PODXL TAFA5 TMPRSS7 ATP2A3

2.37e-05165925a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellThalamus-Hematopoietic|Thalamus / BrainAtlas - Mouse McCarroll V32

GPR65 ARHGAP9 ADAM33 ESPL1 STAB1

2.44e-0516692576d60ac7ac5d1eaf530f0c741d9c48e0bd58396b
ToppCellfacs-Trachea-nan-18m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP2 FN1 SCN1A TSPAN13 TAFA5

2.51e-051679257b1fd19946cee67dae68f0f0d98420abcd532482
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 FN1 TSPAN13 TAFA5 CRISPLD1

2.51e-05167925102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIRREL3 GPR65 SPINK1 TAFA1 ATP2A3

2.74e-05170925c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCD KCNJ12 ADAMTSL3 NOTCH3 GAREM1

2.98e-05173925a37f38478473290fe35aea8684befc3bf95b161f
ToppCellCV-Healthy-4|Healthy / Virus stimulation, Condition and Cluster

PODXL ZNF589 MAFF NR4A1 F12

3.06e-0517492526544cc5f51cb4dc1251e62d9f80b6c956194d38
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRYBA2 CILP2 KCNJ12 TAFA5 TMPRSS7

3.14e-05175925f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRYBA2 CILP2 KCNJ12 TAFA5 TMPRSS7

3.14e-051759257bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SGCD ADAM33 NBEA ADAMTSL3 CDON

3.32e-05177925bd602db857f37869ef76d14c05ef522c509f08ee
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRYBA2 MBNL2 SCN1A C8B SFMBT2

3.32e-051779251dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCD KCNJ12 ADAMTSL3 NOTCH3 GAREM1

3.79e-05182925be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCellwk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CILP2 FBLN2 TAFA1 ADAMTSL3 CRISPLD1

3.79e-051829250e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCD KCNJ12 ADAMTSL3 NOTCH3 GAREM1

3.79e-0518292574dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS4 FN1 SGCD LAMC1 ADAMTSL3

3.79e-051829253dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellnormal_Lung-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

TSPAN13 ARHGAP9 ESPL1 TACSTD2 ALPK2

3.79e-051829258dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS4 FN1 UNC5C LAMC1 ADAMTSL3

3.79e-05182925fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB17 ADAM33 ADAMTSL3 MBNL3 NOTCH3

3.89e-051839250e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB17 ADAM33 ADAMTSL3 MBNL3 NOTCH3

3.89e-05183925cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCellmyeloid-Dendritic_cell-Plasmacytoid_dendritic_cell|World / Lineage, cell class and subclass

KIRREL3 RPS6KA4 TSPAN13 ADAM33 RET

3.99e-0518492511619778bc773ecd1a9867330be04deaf324f31e
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNJ12 TAFA1 ARHGAP9 ADAMTSL3 NOTCH3

3.99e-0518492523c24ab5786af33d605bc445d06117b9da6c6331
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 LAMC1 TAFA5 NR4A1 CDON

4.10e-051859259faa35ceb89ccd2979072286f063687c9f846ce3
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 SGCD MAFF PRKCZ STAB1

4.10e-051859256a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 TSPAN13 NR4A1 ATP2A3

4.10e-05185925e29079ef09aee62c3e9756341db4e59ca9dbf7ac
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 FN1 PODXL CCDC81 CRISPLD1

4.10e-05185925f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZBTB17 ZNF317 SFMBT2 AXIN2 STAB1

4.10e-051859251b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZBTB17 ZNF317 SFMBT2 AXIN2 STAB1

4.10e-0518592502cbf492bc40abebaa93a3a208888afae72fbe06
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 SGCD MAFF PRKCZ STAB1

4.10e-0518592564791056cdbb739136dbef08f4b16e2b5427faad
ToppCellfacs-Large_Intestine-Distal-24m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 TSPAN13 NR4A1 ATP2A3

4.10e-051859252ecc4b76b3645b65c226c2298bff307cc6479172
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP2 THBS4 KCNJ12 MDK CRISPLD1

4.21e-051869254e983de6d2515082f9e555f4f949cec84281c140
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBNL2 UNC5C NBEA RET NOTCH3

4.31e-05187925d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBNL2 UNC5C NBEA RET NOTCH3

4.31e-05187925d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBNL2 UNC5C NBEA RET NOTCH3

4.31e-05187925ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCelldroplet-Large_Intestine-COLON:P+D-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 TSPAN13 NR4A1 ATP2A3

4.31e-05187925a63fa3255ad58f3a73c596df99ce9649fdbaeb39
ToppCelldroplet-Large_Intestine-COLON:P+D|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 TSPAN13 NR4A1 ATP2A3

4.31e-05187925b1bb5c48258a9d058614d23001899dbe44857a1f
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|368C / Donor, Lineage, Cell class and subclass (all cells)

SPINK1 NBEA TACSTD2 AGRN ZFP62

4.31e-05187925b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|368C / Donor, Lineage, Cell class and subclass (all cells)

SPINK1 NBEA TACSTD2 AGRN ZFP62

4.31e-0518792561c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 SPINK1 TSPAN13 NR4A1 ATP2A3

4.42e-05188925bfd3b4f57785596b2bd2c657e0d2d8b0f40ba36d
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN2 FN1 PODXL CRISPLD1 NOTCH3

4.42e-05188925ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

FBLN2 SGCD UNC5C ADAM33 ADAMTSL3

4.42e-05188925706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellP28-Mesenchymal-developing_mesenchymal_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KCNJ12 TAFA1 ARHGAP9 ADAMTSL3 NOTCH3

4.42e-05188925e7681efb4d2de7f1d8a89552fff76a829376bf1b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN2 FN1 PODXL TAFA5 ATP2A3

4.54e-0518992512b6f1c3bf526b90e112374bf937701f645c5780
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 FBLN2 SGCD LAMC1 ADAMTSL3

4.54e-051899256b3b42d758b63a0df62310c34fa3bde421c1afd7
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS4 FBLN2 SGCD LAMC1 ADAMTSL3

4.54e-05189925344b23d3c47d0665dda1cd4856a5e72f1c28cfb3
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN2 PODXL TSPAN13 ATP2A3 CRISPLD1

4.54e-051899251e1afa66b32ae752c0a42b02b80f10205464569c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FN1 SGCD UNC5C PKN2 SFMBT2

4.65e-051909257986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

FBLN2 FN1 PODXL TAFA5 ATP2A3

4.65e-051909251519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN2 PODXL TSPAN13 ATP2A3 CRISPLD1

4.65e-05190925eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN2 PODXL TSPAN13 ATP2A3 CRISPLD1

4.65e-051909253346bfd0474828b3729cffa9f4cc57b04dd30443
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FN1 SGCD UNC5C PKN2 SFMBT2

4.77e-05191925fa380a8752de158974b2ae5e741573439719cc0d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FBLN2 SGCD ADAM33 ADAMTSL3 CDON

4.89e-051929258d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FN1 MAFF NR4A1 CUBN ATP2A3

4.89e-05192925aedddccacf60e884af044cefba6c64ca10ac97d2
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FN1 MAFF NR4A1 CUBN ATP2A3

4.89e-05192925389d5e6d0689371bfe1d0b06e92e0e6e5573567b
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

FBLN2 SGCD UNC5C ADAM33 ADAMTSL3

4.89e-05192925a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS4 FBLN2 ASTN2 ADAMTSL3 CDON

5.01e-0519392564edc1d6fb0fe117767d494cf4a5723bf8be2804
ComputationalTrachea genes.

FBLN2 FN1 GNE MAFF NR4A1 MDK TACSTD2 ATP2A3 NOTCH3 STAB1

2.90e-054155310MODULE_6
ComputationalHeparin binding.

THBS4 FN1 MDK

3.40e-0428533MODULE_385
ComputationalPlacenta genes.

FBLN2 FN1 GNE ZKSCAN7 MAFF PRKCZ TACSTD2 NOTCH3 STAB1

3.86e-04463539MODULE_38
DrugDB04780

THBS4 FBLN2 FN1 LAMC1 PKN2 PRKCZ MDK F12

3.77e-07170908CID005459389
DrugEpitiostanol [2363-58-8]; Down 200; 13uM; HL60; HT_HG-U133A

DNAAF2 MZF1 ZNF589 PKN2 MAFF ZNF225 NR4A1 AGRN

1.11e-061969082922_DN
DrugRaloxifene Hydrochloride

FN1 SPINK1 MBNL2 PODXL LAMC1 MAFF PRKCZ RET NR4A1 ADAMTSL3 CREBBP F12 NOTCH3 CDON

6.53e-068579014ctd:D020849
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

ZBTB17 MBNL2 PKN2 MAFF C8B ZBTB1 STAB1

1.37e-051989072216_UP
Diseasemyotonic disease (implicated_via_orthology)

MBNL2 MBNL1 MBNL3

2.65e-083893DOID:450 (implicated_via_orthology)
Diseasemyotonic dystrophy type 2 (implicated_via_orthology)

MBNL2 MBNL1 MBNL3

2.64e-075893DOID:0050759 (implicated_via_orthology)
Diseasemyotonic dystrophy type 1 (implicated_via_orthology)

MBNL2 MBNL1 MBNL3

5.27e-076893DOID:11722 (implicated_via_orthology)
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

9.00e-062892180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

9.00e-062892cv:C4551859
DiseaseMenke-Hennekam syndrome

CREBBP EP300

9.00e-062892cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

9.00e-062892DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

9.00e-062892cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

9.00e-062892C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

9.00e-062892DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

9.00e-062892C0035934
Diseaseendometriosis (is_marker_for)

SPINK1 MDK DNMT1

5.81e-0525893DOID:289 (is_marker_for)
Diseasepulse pressure measurement

CILP2 FN1 TTLL6 PODXL SGCD MBNL1 FAM76B CLEC18C NBEA PKN2 ADAMTSL3 CRISPLD1 NOTCH3 DNMT1

7.02e-0513928914EFO_0005763
DiseaseCCHS WITH HIRSCHSPRUNG DISEASE

RET GDNF

8.94e-055892C1859049
DiseaseAganglionic megacolon

RET GDNF

1.34e-046892cv:C0019569
DiseaseCongenital central hypoventilation

RET GDNF

1.87e-047892C1275808
DiseaseAdenocarcinoma of large intestine

PRKCZ RET EP300 AXIN2

2.08e-0496894C1319315
DiseaseCarcinoma, Transitional Cell

ESPL1 CREBBP EP300

2.60e-0441893C0007138
DiseaseColorectal Carcinoma

FBLN2 FN1 LAMC1 PRKCZ RET CUBN ADAMTSL3 EP300 AXIN2

2.71e-04702899C0009402
DiseaseHirschsprung's disease (is_implicated_in)

RET GDNF

4.86e-0411892DOID:10487 (is_implicated_in)
DiseaseHirschsprung's disease (implicated_via_orthology)

RET GDNF

5.82e-0412892DOID:10487 (implicated_via_orthology)
DiseaseMyasthenia gravis

FAM76B SFMBT2

6.87e-0413892EFO_0004991
DiseaseAganglionosis, Colonic

RET GDNF

9.21e-0415892C0085758
DiseaseAganglionosis, Rectosigmoid Colon

RET GDNF

9.21e-0415892C1257840
DiseasePheochromocytoma, Extra-Adrenal

RET GDNF

1.05e-0316892C1257877
Diseaseautism spectrum disorder (implicated_via_orthology)

SCN1A LAMC1 NBEA CREBBP

1.18e-03152894DOID:0060041 (implicated_via_orthology)
DiseaseDementia

NOTCH3 DNMT1

1.19e-0317892C0497327
DiseaseCongenital Intestinal Aganglionosis

RET GDNF

1.19e-0317892C3661523
Diseasebanks of the superior temporal sulcus volume measurement

SGCD TAFA1

1.19e-0317892EFO_0010286
Diseaseprostate cancer (is_marker_for)

SPINK1 SRD5A1 EP300 DNMT1

1.29e-03156894DOID:10283 (is_marker_for)
Diseaseglucose homeostasis measurement, acute insulin response measurement

ASTN2 ATP2A3

1.33e-0318892EFO_0006831, EFO_0006896
Diseasecaudal middle frontal gyrus volume measurement

ASTN2 TAFA5

1.33e-0318892EFO_0010290
Diseaseglomerulonephritis (is_marker_for)

FN1 EP300

1.49e-0319892DOID:2921 (is_marker_for)
Diseaseresponse to supplemental oxygen

CRYBA2 ASTN2

1.49e-0319892EFO_0009796
DiseasePheochromocytoma

RET GDNF

1.49e-0319892C0031511
DiseaseAmphetamine-Related Disorders

ASTN2 CUBN GDNF

1.53e-0375893C0236733
DiseaseAmphetamine Abuse

ASTN2 CUBN GDNF

1.53e-0375893C0236807
DiseaseAmphetamine Addiction

ASTN2 CUBN GDNF

1.53e-0375893C0236804
Diseasemucocutaneous lymph node syndrome

ITPKC BTBD1 CUBN

1.59e-0376893EFO_0004246
Diseaseaspartate aminotransferase measurement

CILP2 SPINK1 MBNL1 FAM76B ASTN2 ARHGAP9 PKN2 CUBN ALPK2

1.63e-03904899EFO_0004736
DiseaseLung diseases

DNAAF2 RET GDNF

1.71e-0378893C0024115
DiseaseGlioblastoma

FN1 GDNF NOTCH3

1.78e-0379893C0017636
Diseasecup-to-disc ratio measurement

CROCC2 FAM76B ARHGAP9 PKN2 ADAMTSL3 CRISPLD1

1.94e-03430896EFO_0006939
DiseaseGiant Cell Glioblastoma

FN1 GDNF NOTCH3

2.12e-0384893C0334588
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

RET GDNF

2.18e-0323892C1708353
Diseaseairway responsiveness measurement

SGCD LRCH3

2.38e-0324892EFO_0006897
DiseaseCarcinoma, Pancreatic Ductal

NOTCH3 DNMT1

2.38e-0324892C0887833
Diseasehair color

KIRREL3 SGCD MBNL1 CRISPLD1 AXIN2

2.54e-03311895EFO_0003924
DiseaseProstatic Neoplasms

SPINK1 PODXL SRD5A1 LAMC1 PRKCZ CREBBP DNMT1

2.63e-03616897C0033578
DiseaseMalignant neoplasm of prostate

SPINK1 PODXL SRD5A1 LAMC1 PRKCZ CREBBP DNMT1

2.63e-03616897C0376358
Diseasecolon carcinoma

ARHGAP9 CRISPLD1

2.79e-0326892EFO_1001950
DiseaseSquamous cell carcinoma of esophagus

CREBBP EP300 NOTCH3

3.01e-0395893C0279626
DiseaseColorectal cancer

EP300 AXIN2

3.01e-0327892cv:C0346629
DiseaseCOLORECTAL CANCER

EP300 AXIN2

3.01e-0327892114500
DiseaseNeoplasm of the large intestine

EP300 AXIN2

3.01e-0327892cv:C0009404

Protein segments in the cluster

PeptideGeneStartEntry
CQRREQANGEVRQCN

EP300

351

Q09472
RCAQDACQAQAREKE

CCDC89

196

Q8N998
NAFKRRRCGVCEVCQ

DNMT1

646

P26358
LRRESEAGQKCCTFQ

ALPK2

2051

Q86TB3
CQLLRRACARQENVF

AGRN

296

O00468
KCQRREQANGEVRAC

CREBBP

366

Q92793
DFQGRRCRLLSDCAN

CRYBA2

21

P53672
PKQRCCVASQQRDRN

AXIN2

711

Q9Y2T1
VCQSRRCRKNAFQEL

ADAM33

636

Q9BZ11
ARCDARVQNLQAECR

ANKRD36B

1191

Q8N2N9
CFATQRQCREEILKG

AGO3

456

Q9H9G7
QRQACRTARCFARVE

ATP2A3

666

Q93084
GCTRNFKCVSDRQVD

ASTN2

661

O75129
DGRILKRFCQCEQRS

ITPKC

426

Q96DU7
RNRCQFCRFQKCLAV

NR4A1

316

P22736
GCCHQRLSQRKDQQR

PODXL

481

O00592
AKCRRNVENFLEACR

LRCH3

716

Q96II8
NRGYAASCRVKRVCQ

MAFF

61

Q9ULX9
RCRNRFVKKNGQCNI

KCNJ12

41

Q14500
RRCFVNVCSNALVGA

DNAAF2

86

Q9NVR5
FREGTCGAQTQRIRC

MDK

56

P21741
RNRKAVLCQRCGSRV

RABIF

16

P47224
CQNTKGSFYCQARQR

FBLN2

781

P98095
QRIQCRSENSKGVYC

FBXW11

231

Q9UKB1
NRCDQFRGSVRSKCA

GAREM1

476

Q9H706
RNQATCLDRIGQFTC

NOTCH3

441

Q9UM47
VCDRCGQRFAQASTL

MYNN

416

Q9NPC7
CKQQCAFDRKEEGRR

FAM76B

106

Q5HYJ3
NRRLVSDKVGQACCR

GDNF

166

P39905
RRCRQRQSGQEFAVK

RPS6KA4

426

O75676
SCQVGRLGQREARCF

MSLNL

271

Q96KJ4
NECVLCFENRKRQTS

SPINK1

56

P00995
SRQNRGFRAQFRQAC

CUBN

1606

O60494
RRQACDAILRACNQQ

ESPL1

46

Q14674
NNRKLRVCVATCNRA

GNE

6

Q9Y223
RRCKQCQRRTSNVGE

CCDC81

621

Q6ZN84
CRCARAQSRVGQLQK

CROCC2

1401

H7BZ55
GRITCTSRNRCNDQD

FN1

221

P02751
EVRLRDQCKGTTCNR

CRISPLD1

296

Q9H336
RGKECCINRFQQVES

BTBD1

326

Q9H0C5
CRNCRNNNRCFTKTN

CDON

1111

Q4KMG0
RLEVCREYQRGNCNR

MBNL1

181

Q9NR56
LEVCRQFQRGTCSRS

MBNL2

16

Q5VZF2
VCREFQRGNCARGET

MBNL2

181

Q5VZF2
KLEVCREFQRGNCTR

MBNL3

176

Q9NUK0
VAFCCARSQRNLKGV

KIRREL3

556

Q8IZU9
RCRENFFRLGNNEAC

LAMC1

381

P11047
RCNQGCVSRSKRDIS

CUZD1

511

Q86UP6
CLRGKECSINRFQQV

BTBD2

366

Q9BX70
SCSGRRKTRQRQCNN

C8B

556

P07358
CKVCFEKFGHRQQRR

NHLRC1

26

Q6VVB1
YRTEQAAVARCQCKG

F12

151

P00748
RCCNKNRIEERSQTV

TAFA1

51

Q7Z5A9
IARQTARCACRKGQI

TAFA5

61

Q7Z5A7
RCRNRFVKKNGQCNI

KCNJ18

41

B7U540
QVFRCAAARGSELCQ

SIGLEC15

91

Q6ZMC9
EGRFKARQCNQTSVC

TACSTD2

111

P09758
RNCLECRQRQRDRGN

NBEA

1481

Q8NFP9
QFNLQDFRCCAVLGR

PKN2

651

Q16513
VQRFKCCQINVEEGR

SCN1A

1186

P35498
RVREAGQNVTFCCKA

CILP2

301

Q8IUL8
DQRCKTRNRYICQFA

CLEC18A

421

A5D8T8
NQRCKTRNRYICQFA

CLEC18C

421

Q8NCF0
TGDQIRGCKAERNCR

THBS4

411

P35443
VSRCSRQCQEGQVRR

TAS1R3

496

Q7RTX0
DIQRNLNCCGFRSVN

TSPAN13

121

O95857
NRTFKCGNDICFRKQ

TMPRSS7

561

Q7RTY8
RQKVFEICVCANGRL

SGCD

256

Q92629
RCRPAQNNATFDCKV

SLMAP

36

Q14BN4
AAICCKNRRGRNNKD

THAP5

6

Q7Z6K1
VRTSDQVANFCRRVC

SFMBT2

616

Q5VUG0
KCVNCTRRFRCTQGF

STAB1

1271

Q9NY15
RVQDVACRCRNGFVG

STAB1

2301

Q9NY15
RDQVFGCQLESLCQR

ARHGAP9

536

Q9BRR9
RGQFLQQCCSREMRI

TTLL6

406

Q8N841
KFCTGRCNTSQRQRK

GPR65

306

Q8IYL9
ARRFAQIGKVCVENC

RET

416

P07949
GNVNFARRTSCNRCG

ZRANB2

21

O95218
FVCQTCGKQFLRERQ

ZBTB1

606

Q9Y2K1
DICCKSFRSRANLNR

ZNF225

291

Q9UK10
VCDQCGKRFSQRKNL

ZNF689

206

Q96CS4
CDKCGRGFNRVDNLR

ZBTB17

616

Q13105
CSECGKTFRQRSNLR

ZNF792

536

Q3KQV3
RCNECGKAFNIRSNL

ZFP62

841

Q8NB50
NECGRAFCSNRNLID

ZKSCAN7

526

Q9P0L1
CAVGCAVFARNRQTN

SRD5A1

21

P18405
RNDFCNKQSDRCVVL

TRAPPC10

151

P48553
FTNKCERAGCRQREM

ZFAND2B

96

Q8WV99
SSDKRQSQVCRECGR

ZNF589

241

Q86UQ0
QSQVCRECGRGFSRK

ZNF589

246

Q86UQ0
VCNSRCGRGYQKRTR

UNC5C

271

O95185
RVECRQCGKAFRNQS

ZNF317

501

Q96PQ6
RNCEGQNIRYKTCSN

ADAMTSL3

106

P82987
KRFNRRAYCGQCSER

PRKCZ

136

Q05513
RCAECGQSFRQRSNL

MZF1

441

P28698