Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 NAV2 NAV1 KIF18B DNAH9

2.12e-0644111813GO:0016887
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B LGALS9

6.92e-0671183GO:0048030
GeneOntologyMolecularFunctionpyrophosphatase activity

PRUNE2 ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 NAV2 NAV1 AGAP7P KIF18B AGAP4 DNAH9 AGAP6

8.78e-0683911817GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

PRUNE2 ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 NAV2 NAV1 AGAP7P KIF18B AGAP4 DNAH9 AGAP6

8.91e-0684011817GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

PRUNE2 ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 NAV2 NAV1 AGAP7P KIF18B AGAP4 DNAH9 AGAP6

8.91e-0684011817GO:0016818
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

1.03e-05491185GO:0140359
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 NAV2 NAV1 AGAP7P KIF18B AGAP4 DNAH9 AGAP6

1.31e-0577511816GO:0017111
GeneOntologyMolecularFunctionATP-dependent activity

ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 DNAH1 NAV2 NAV1 KIF18B DNAH9

1.60e-0561411814GO:0140657
GeneOntologyMolecularFunctiongalactoside binding

LGALS9C LGALS9B LGALS9

1.65e-0591183GO:0016936
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ABCA2 ABCA3 ABCA7

2.13e-05281184GO:0140326
GeneOntologyMolecularFunctionapolipoprotein A-I receptor activity

ABCA1 ABCA7

3.46e-0521182GO:0034188
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA1 ABCA7

1.03e-0431182GO:0030226
GeneOntologyMolecularFunctionfloppase activity

ABCA1 ABCA2 ABCA7

1.07e-04161183GO:0140328
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCA1 ABCA2

2.06e-0441182GO:0046623
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9C LGALS9B LGALS9

2.13e-04201183GO:0070492
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA1 ABCA3 ABCA7

2.13e-04201183GO:0008525
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA1 ABCA2 ABCA3 ABCA7

2.34e-04511184GO:0140303
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR3 FGFR4

3.42e-0451182GO:0005007
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

4.74e-041091185GO:0042626
GeneOntologyMolecularFunctionMAP kinase kinase kinase activity

MAP3K14 MAP3K7 MAP3K19

5.31e-04271183GO:0004709
GeneOntologyMolecularFunctionpoly(A) binding

PABPC1L2A PABPC5 DDX1

6.57e-04291183GO:0008143
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCA1 ABCA7

9.47e-0481182GO:0090554
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

LGALS9C LGALS9B LGALS9 CCNT1

1.18e-03781184GO:0043539
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ABCA1 ABCA7

1.21e-0391182GO:0090556
GeneOntologyMolecularFunctionSNARE binding

ABCA1 SYT17 GRIK1 ADCY6 UVRAG

1.29e-031361185GO:0000149
GeneOntologyMolecularFunctionpoly-purine tract binding

PABPC1L2A PABPC5 DDX1

1.35e-03371183GO:0070717
GeneOntologyMolecularFunctionscaffold protein binding

GRIK1 ADCY6 KCNQ1 MAP3K7

2.26e-03931184GO:0097110
GeneOntologyMolecularFunctionhelicase activity

DHX37 YTHDC2 CHD8 DDX1 NAV2

2.48e-031581185GO:0004386
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

6.90e-0741163GO:0043322
GeneOntologyBiologicalProcessregulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

9.51e-0681163GO:0043321
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

LGALS9C LGALS9B CRB1 LGALS9 HMCN1

2.80e-05631165GO:0007157
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

7.51e-05151163GO:2000562
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9C LGALS9B LGALS9

7.51e-05151163GO:0032815
GeneOntologyBiologicalProcessphospholipid efflux

ABCA1 ABCA3 ABCA7

7.51e-05151163GO:0033700
GeneOntologyBiologicalProcessnegative regulation of leukocyte degranulation

LGALS9C LGALS9B LGALS9

1.11e-04171163GO:0043301
GeneOntologyBiologicalProcesspositive regulation of oxidoreductase activity

LGALS9C RIPK3 LGALS9B LGALS9

1.29e-04461164GO:0051353
GeneOntologyBiologicalProcessnatural killer cell degranulation

LGALS9C LGALS9B LGALS9

1.33e-04181163GO:0043320
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

1.57e-04191163GO:0046642
GeneOntologyBiologicalProcesspositive regulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

1.57e-04191163GO:1900426
GeneOntologyBiologicalProcessregulation of T cell chemotaxis

LGALS9C LGALS9B LGALS9

1.84e-04201163GO:0010819
GeneOntologyBiologicalProcessregulation of phospholipid efflux

ABCA3 ABCA7

1.87e-0441162GO:1902994
GeneOntologyBiologicalProcesspositive regulation of phospholipid efflux

ABCA3 ABCA7

1.87e-0441162GO:1902995
GeneOntologyBiologicalProcessalveolar secondary septum development

FGFR3 FGFR4

1.87e-0441162GO:0061144
GeneOntologyBiologicalProcessregulation of natural killer cell differentiation

LGALS9C LGALS9B LGALS9

2.14e-04211163GO:0032823
GeneOntologyBiologicalProcessregulation of cholesterol efflux

ABCA1 ABCA2 ABCA3 ABCA7

2.78e-04561164GO:0010874
GeneOntologyBiologicalProcessregulation of T cell migration

LGALS9C RIPK3 LGALS9B LGALS9

2.78e-04561164GO:2000404
GeneOntologyBiologicalProcesssphingolipid translocation

ABCA1 ABCA2

3.10e-0451162GO:0099039
GeneOntologyBiologicalProcesslipid translocation

ABCA1 ABCA2 ABCA3 ABCA7

3.63e-04601164GO:0034204
GeneOntologyBiologicalProcessregulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

4.10e-04261163GO:1900424
DomainABC_A

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

5.19e-09121115IPR026082
Domain-

LGALS9C LGALS9B CRB1 LGALS9 THBS2 EGFLAM ADGRD1

1.55e-069511172.60.120.200
DomainAAA+_ATPase

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9 NAV2 NAV1 DNAH9

2.32e-061441118IPR003593
DomainAAA

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9 NAV2 NAV1 DNAH9

2.32e-061441118SM00382
DomainConA-like_dom

LGALS9C LGALS9B DDX1 CRB1 LGALS9 THBS2 EGFLAM HERC1 ADGRD1

6.38e-062191119IPR013320
DomainABC_tran

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

9.46e-06481115PF00005
DomainABC_TRANSPORTER_2

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

9.46e-06481115PS50893
DomainABC_TRANSPORTER_1

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

1.05e-05491115PS00211
DomainABC_transporter-like

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

1.16e-05501115IPR003439
DomainArfGap

GIT2 AGAP7P AGAP4 AGAP6

2.50e-05291114SM00105
DomainArfGap

GIT2 AGAP7P AGAP4 AGAP6

2.50e-05291114PF01412
DomainARFGAP

GIT2 AGAP7P AGAP4 AGAP6

2.50e-05291114PS50115
DomainArfGAP

GIT2 AGAP7P AGAP4 AGAP6

2.50e-05291114IPR001164
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

8.82e-05151113PF00337
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

8.82e-05151113SM00908
DomainGALECTIN

LGALS9C LGALS9B LGALS9

8.82e-05151113PS51304
DomainGalectin_CRD

LGALS9C LGALS9B LGALS9

8.82e-05151113IPR001079
DomainGLECT

LGALS9C LGALS9B LGALS9

8.82e-05151113SM00276
DomainABC_transporter_CS

ABCA1 ABCA2 ABCA3 ABCA7

1.11e-04421114IPR017871
DomainFGF_rcpt_fam

FGFR3 FGFR4

2.08e-0441112IPR016248
Domain-

ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 DNAH1 NAV2 NAV1 DNAH9

4.84e-04746111133.40.50.300
DomainP-loop_NTPase

ABCA1 ABCA2 ABCA3 DHX37 YTHDC2 CHD8 ABCA7 ABCA9 DDX1 DNAH1 NAV2 NAV1 KIF18B DNAH9

4.99e-0484811114IPR027417
DomainDEAH_ATP_HELICASE

DHX37 YTHDC2 CHD8

1.48e-03381113PS00690
DomainPROTEIN_KINASE_ATP

FLT4 GAK RIPK3 SPEG MAP3K14 FGFR3 FGFR4 MAP3K7 MAP3K19

1.67e-034591119PS00107
DomainProtein_kinase_ATP_BS

FLT4 RIPK3 SPEG MAP3K14 FGFR3 FGFR4 MAP3K7 MAP3K19

1.92e-033791118IPR017441
DomainProt_kinase_dom

FLT4 GAK RIPK3 SPEG MAP3K14 FGFR3 FGFR4 MAP3K7 MAP3K19

2.56e-034891119IPR000719
DomainPROTEIN_KINASE_DOM

FLT4 GAK RIPK3 SPEG MAP3K14 FGFR3 FGFR4 MAP3K7 MAP3K19

2.71e-034931119PS50011
DomainDynein_heavy_chain_D4_dom

DNAH1 DNAH9

3.04e-03141112IPR024317
DomainDynein_HC_stalk

DNAH1 DNAH9

3.04e-03141112IPR024743
DomainDynein_heavy_dom-2

DNAH1 DNAH9

3.04e-03141112IPR013602
DomainDHC_N2

DNAH1 DNAH9

3.04e-03141112PF08393
DomainMT

DNAH1 DNAH9

3.04e-03141112PF12777
DomainAAA_8

DNAH1 DNAH9

3.04e-03141112PF12780
DomainATPase_dyneun-rel_AAA

DNAH1 DNAH9

3.04e-03141112IPR011704
DomainAAA_5

DNAH1 DNAH9

3.04e-03141112PF07728
DomainDHC_fam

DNAH1 DNAH9

3.49e-03151112IPR026983
DomainDynein_heavy_dom

DNAH1 DNAH9

3.49e-03151112IPR004273
DomainDynein_heavy

DNAH1 DNAH9

3.49e-03151112PF03028
DomainHelicase_C

DHX37 YTHDC2 CHD8 DDX1

3.81e-031071114PF00271
DomainHELICc

DHX37 YTHDC2 CHD8 DDX1

3.81e-031071114SM00490
DomainANK

SLF1 YTHDC2 GIT2 AGAP7P AGAP4 AGAP6

3.88e-032511116SM00248
DomainHelicase_C

DHX37 YTHDC2 CHD8 DDX1

3.94e-031081114IPR001650
DomainANK_REPEAT

SLF1 YTHDC2 GIT2 AGAP7P AGAP4 AGAP6

4.04e-032531116PS50088
DomainHELICASE_CTER

DHX37 YTHDC2 CHD8 DDX1

4.07e-031091114PS51194
DomainHELICASE_ATP_BIND_1

DHX37 YTHDC2 CHD8 DDX1

4.07e-031091114PS51192
DomainDEXDc

DHX37 YTHDC2 CHD8 DDX1

4.07e-031091114SM00487
DomainAnkyrin_rpt-contain_dom

SLF1 YTHDC2 GIT2 AGAP7P AGAP4 AGAP6

4.11e-032541116IPR020683
DomainANK_REP_REGION

SLF1 YTHDC2 GIT2 AGAP7P AGAP4 AGAP6

4.11e-032541116PS50297
DomainHelicase_ATP-bd

DHX37 YTHDC2 CHD8 DDX1

4.21e-031101114IPR014001
DomainPoly(ADP-ribose)pol_cat_dom

PARP2 PARP15

4.49e-03171112IPR012317
DomainPARP_CATALYTIC

PARP2 PARP15

4.49e-03171112PS51059
DomainPARP

PARP2 PARP15

4.49e-03171112PF00644
DomainDUF1605

DHX37 YTHDC2

4.49e-03171112IPR011709
DomainOB_NTP_bind

DHX37 YTHDC2

4.49e-03171112PF07717
Domain-

PARP2 PARP15

4.49e-031711123.90.228.10
DomainAnkyrin_rpt

SLF1 YTHDC2 GIT2 AGAP7P AGAP4 AGAP6

4.78e-032621116IPR002110
DomainLaminin_G

CRB1 THBS2 EGFLAM

4.97e-03581113IPR001791
DomainKinase-like_dom

FLT4 GAK RIPK3 SPEG MAP3K14 FGFR3 FGFR4 MAP3K7 MAP3K19

5.03e-035421119IPR011009
DomainHA2

DHX37 YTHDC2

5.03e-03181112SM00847
DomainHA2

DHX37 YTHDC2

5.03e-03181112PF04408
DomainHelicase-assoc_dom

DHX37 YTHDC2

5.03e-03181112IPR007502
DomainIg_I-set

FLT4 SPEG HMCN1 FGFR3 FGFR4

5.56e-031901115IPR013098
DomainI-set

FLT4 SPEG HMCN1 FGFR3 FGFR4

5.56e-031901115PF07679
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA2 ABCA3 ABCA7 ABCA9

2.16e-0617804MM14552
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA2 ABCA3 ABCA7 ABCA9

2.77e-0618804M524
PathwayKEGG_ABC_TRANSPORTERS

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

4.74e-0644805M11911
Pubmed

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

ABCA1 ABCA2 ABCA3 ABCA7

9.65e-098121424293640
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9C LGALS9B LGALS9

4.11e-083121319776007
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B LGALS9

4.11e-083121333316546
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9C LGALS9B LGALS9

4.11e-08312139038233
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B LGALS9

4.11e-083121328704475
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B LGALS9

4.11e-083121323836896
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B LGALS9

4.11e-08312137890611
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9C LGALS9B LGALS9

4.11e-083121322341088
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B LGALS9

4.11e-083121332380082
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B LGALS9

4.11e-083121323667648
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B LGALS9

4.11e-083121328877989
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B LGALS9

4.11e-083121319800850
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9C LGALS9B LGALS9

4.11e-083121338987795
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B LGALS9

4.11e-083121337105392
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B LGALS9

4.11e-083121336479526
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B LGALS9

4.11e-083121323242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B LGALS9

4.11e-083121319851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B LGALS9

4.11e-083121333923930
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B LGALS9

4.11e-083121331969388
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9C LGALS9B LGALS9

4.11e-083121335241678
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9C LGALS9B LGALS9

4.11e-083121322627368
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9C LGALS9B LGALS9

4.11e-083121333153471
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9C LGALS9B LGALS9

4.11e-083121322052881
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9C LGALS9B LGALS9

4.11e-083121335643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9C LGALS9B LGALS9

4.11e-083121323408620
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9C LGALS9B LGALS9

4.11e-083121329458010
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9C LGALS9B LGALS9

4.11e-083121326582205
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9C LGALS9B LGALS9

4.11e-08312139153289
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9C LGALS9B LGALS9

4.11e-083121318974023
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9C LGALS9B LGALS9

4.11e-083121323144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9C LGALS9B LGALS9

4.11e-083121329651447
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9C LGALS9B LGALS9

4.11e-083121321146220
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9C LGALS9B LGALS9

4.11e-083121328990062
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9C LGALS9B LGALS9

4.11e-083121318579572
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9C LGALS9B LGALS9

4.11e-083121316990264
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9C LGALS9B LGALS9

4.11e-083121318005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9C LGALS9B LGALS9

4.11e-083121323585851
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9C LGALS9B LGALS9

4.11e-083121324477688
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9C LGALS9B LGALS9

4.11e-083121329433546
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9C LGALS9B LGALS9

4.11e-083121325898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9C LGALS9B LGALS9

4.11e-083121331937306
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9C LGALS9B LGALS9

4.11e-083121321426359
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9C LGALS9B LGALS9

4.11e-083121318282810
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9C LGALS9B LGALS9

4.11e-083121324083426
Pubmed

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9C LGALS9B LGALS9

4.11e-083121337279535
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9C LGALS9B LGALS9

4.11e-083121325931247
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9C LGALS9B LGALS9

4.11e-083121317560833
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

GAPVD1 SHROOM3 ABCA2 FBF1 TRIOBP CHD8 TUBGCP6 SULF2 SMG7 NAV2 AGAP7P AGAP4 AGAP6

4.43e-085291211314621295
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

SMG7 PIN1 ENAH DZIP3 AGAP7P MAP3K7 AGAP4 AGAP6 PRRC2B

7.79e-08218121933378226
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PRUNE2 TRIOBP CHD8 GIT2 ADCY6 SULF2 SMG7 NAV2 PCNT

1.02e-07225121912168954
Pubmed

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

FBF1 CEP89 MKI67 CUX1 PCNT

1.03e-0733121530626697
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9C LGALS9B LGALS9

1.64e-074121338686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9C LGALS9B LGALS9

1.64e-074121322677125
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9C LGALS9B LGALS9

1.64e-074121319234217
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9C LGALS9B LGALS9

1.64e-074121335715604
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9C LGALS9B LGALS9

1.64e-074121319017954
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9C LGALS9B LGALS9

1.64e-074121336459823
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9C LGALS9B LGALS9

1.64e-074121329611821
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9C LGALS9B LGALS9

1.64e-074121333727589
Pubmed

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.

LGALS9C LGALS9B LGALS9

1.64e-074121325578313
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9C LGALS9B LGALS9

1.64e-074121318826117
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9C LGALS9B LGALS9

1.64e-074121338853593
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9C LGALS9B LGALS9

1.64e-074121321575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9C LGALS9B LGALS9

1.64e-074121318346632
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9C LGALS9B LGALS9

1.64e-074121319670381
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9C LGALS9B LGALS9

1.64e-074121325450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9C LGALS9B LGALS9

1.64e-074121316286920
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9C LGALS9B LGALS9

1.64e-074121334369876
Pubmed

Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.

LGALS9C LGALS9B LGALS9

1.64e-074121333203936
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9C LGALS9B LGALS9

1.64e-074121333963043
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9C LGALS9B LGALS9

1.64e-074121333107565
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9C LGALS9B LGALS9

1.64e-074121330763585
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9C LGALS9B LGALS9

1.64e-074121319362679
Pubmed

Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.

LGALS9C LGALS9B LGALS9

1.64e-074121329844236
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9C LGALS9B LGALS9

1.64e-074121320463811
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9C LGALS9B LGALS9

1.64e-074121332855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9C LGALS9B LGALS9

1.64e-074121323657851
Pubmed

The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.

LGALS9C LGALS9B LGALS9

1.64e-074121324333756
Pubmed

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

LGALS9C LGALS9B LGALS9

1.64e-074121324958847
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS9C LGALS9B LGALS9

1.64e-074121330120235
Pubmed

Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.

LGALS9C LGALS9B LGALS9

1.64e-074121311839756
Pubmed

Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.

LGALS9C LGALS9B LGALS9

1.64e-074121322021615
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CHAF1A NTAQ1 FBF1 YTHDC2 CHD8 ABCA7 PSMG3-AS1 ADCY6 TUBGCP6 CCNT1 SULF2 SMG7 USP7 ACTL6B KIF18B MGA PRRC2B

3.45e-0711161211731753913
Pubmed

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.

LGALS9C LGALS9B LGALS9

4.09e-075121328951537
Pubmed

Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner.

LGALS9C LGALS9B LGALS9

4.09e-075121334847625
Pubmed

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.

ABCA1 ABCA3 ABCA7

4.09e-075121317142808
Pubmed

Astrocyte galectin-9 potentiates microglial TNF secretion.

LGALS9C LGALS9B LGALS9

4.09e-075121325158758
Pubmed

Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy.

LGALS9C LGALS9B LGALS9

4.09e-075121326278059
Pubmed

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.

LGALS9C LGALS9B LGALS9

4.09e-075121321385853
Pubmed

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.

LGALS9C LGALS9B LGALS9

4.09e-075121329242193
Pubmed

Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice.

LGALS9C LGALS9B LGALS9

4.09e-075121322469568
Pubmed

C/EBPzeta (CHOP/Gadd153) is a negative regulator of LPS-induced IL-6 expression in B cells.

LGALS9C LGALS9B LGALS9

4.09e-075121319782405
Pubmed

Embryonic implantation in galectin 1/galectin 3 double mutant mice.

LGALS9C LGALS9B LGALS9

4.09e-07512139566950
Pubmed

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

LGALS9C LGALS9B LGALS9

4.09e-075121337352334
Pubmed

Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model.

LGALS9C LGALS9B LGALS9

4.09e-075121333664349
Pubmed

The glucose transporter 2 regulates CD8+ T cell function via environment sensing.

LGALS9C LGALS9B LGALS9

4.09e-075121337884694
Pubmed

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.

LGALS9C LGALS9B LGALS9

8.15e-076121328394331
Pubmed

Tim3 binding to galectin-9 stimulates antimicrobial immunity.

LGALS9C LGALS9B LGALS9

8.15e-076121320937702
Pubmed

Galectins in mouse embryogenesis.

LGALS9C LGALS9B LGALS9

8.15e-07612138674632
Pubmed

Tim-3/galectin-9 regulate the homeostasis of hepatic NKT cells in a murine model of nonalcoholic fatty liver disease.

LGALS9C LGALS9B LGALS9

8.15e-076121323296703
InteractionMAPRE3 interactions

FILIP1 NCKAP5 SPECC1 GAS2L1 KIAA1217 NAV2 NAV1 KIF18B PCNT

9.15e-062301199int:MAPRE3
InteractionC3orf52 interactions

ABCA2 FLT4 ABCA3 FOLH1 RETSAT ABCA7 ADCY6 FCGRT MGA CUX1

1.35e-0530511910int:C3orf52
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA2 ABCA3 ABCA7 ABCA9

1.58e-0914715805
GeneFamilyArfGAPs

GIT2 AGAP7P AGAP4 AGAP6

8.20e-0633714395
GeneFamilyGalectins

LGALS9C LGALS9B LGALS9

2.55e-0515713629
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K14 MAP3K7 MAP3K19

1.11e-0424713654
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FLT4 SPEG HMCN1 FGFR3 FGFR4

4.27e-04161715593
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT4 FGFR3 FGFR4

5.17e-0440713321
GeneFamilyDyneins, axonemal

DNAH1 DNAH9

1.99e-0317712536
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6

1.99e-03177121291
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP2 PARP15

1.99e-0317712684
GeneFamilyAnkyrin repeat domain containing

SLF1 GIT2 AGAP7P AGAP4 AGAP6

2.62e-03242715403
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIOBP AGAP7P AGAP4 AGAP6

8.78e-03206714682
CoexpressionHAY_BONE_MARROW_STROMAL

FILIP1 EBF3 NCKAP5 PABPC5 PTPN21 ABCA9 LIFR THBS2 KIAA1217 ENAH NAV2 KIAA1755 EGFLAM FGFR3

1.26e-0576712114M39209
CoexpressionHALLMARK_BILE_ACID_METABOLISM

ABCA1 ABCA2 ABCA3 RETSAT ABCA9 LIPE

1.37e-051121216M5948
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPEG SPECC1 THBS2 ANTXR2 ENAH KIAA1755 ADGRD1

6.22e-0819612081522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GATM NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1 UVRAG

6.22e-081961208553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GATM NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1 UVRAG

6.22e-081961208d376168e15ec1cf618723259966c76be3698b9b0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPEG SPECC1 THBS2 ANTXR2 ENAH KIAA1755 ADGRD1

6.22e-0819612081c8294014713684b50885e638668f2ce75f357f0
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAP3K14 SPECC1 ABCA7 SULF2 ANTXR2 SLC24A4 NAV1

2.79e-071611207cd41abb7ae659d3d314281783a0aaad562b26037
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CDCA3 LGALS9B FBF1 NAV2 NLE1 KIF18B DNAH9

4.20e-071711207b113fbebb89056af0b9c775d2fb6552206a80467
ToppCellChildren_(3_yrs)-Immune-dendritic_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAP3K14 SPECC1 SULF2 ANTXR2 SLC24A4 NAV1 UVRAG

4.20e-0717112076a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMYND15 PRUNE2 ABCA1 GATM ABCA9 SULF2 FCGRT

4.37e-071721207f0e767a20d93e546ce278db67dbd779cc68af533
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMYND15 PRUNE2 ABCA1 GATM ABCA9 SULF2 FCGRT

4.72e-071741207f520b79d277e286c9bb5d091e6c94e7ec7e46699
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF3 SPECC1 ABCA9 THBS2 NAV1 KIAA1755 EGFLAM

6.39e-071821207fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GATM NCKAP5 SPECC1 LGALS9 FCGRT NAV1 UVRAG

9.80e-0719412076af2971d83f5ad6aed16d0ceb8bfc52f3947bc10
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GATM NCKAP5 SPECC1 LGALS9 FCGRT NAV1 UVRAG

9.80e-0719412075c60670ec24470225fabaa6071fdb4ef6e579840
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 THBS2 ANTXR2 ENAH ADGRD1

1.01e-06195120749c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 THBS2 ANTXR2 ENAH ADGRD1

1.01e-061951207dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1 UVRAG

1.05e-061961207e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1 UVRAG

1.05e-0619612074a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1 UVRAG

1.20e-06200120786f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA1 EBF3 ABCA9 THBS2 NAV2 NAV1 ADGRD1

1.20e-0620012070c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell(51)_cDC1|World / shred on Cell_type and subtype

ZMYND15 NCKAP5 LGALS9 SULF2 SLC24A4 FCGRT NAV1

1.37e-062041207a8cf4180c406674b7541917d1fc6127686ba5f8a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 THBS2 KIAA1755 ADGRD1

4.16e-061561206d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 THBS2 KIAA1755 ADGRD1

4.16e-061561206363f1b661048d25895e2b8681c82894c957b29c0
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 ABCA1 GATM ABCA9 FCGRT MKI67

5.95e-061661206bb8135119dc37fdbba476599a56d368f422688dc
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

ZMYND15 MAP3K14 NCKAP5 SULF2 SLC24A4 NAV1

5.95e-0616612060590e404f45afce90e20f93f90a3def83949c66b
ToppCelldroplet-Lung-nan-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 CHAF1A GATM CFAP77 MKI67 KIF18B

6.37e-06168120696f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 ANTXR2 ENAH NAV2

6.81e-061701206fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 ANTXR2 ENAH NAV2

6.81e-06170120603044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

MAP3K14 SPECC1 SULF2 ANTXR2 SLC24A4 UVRAG

7.05e-0617112066a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCellClub-club-15|World / Class top

ZMYND15 CDCA3 DDIAS SULF2 KIF18B BORA

8.04e-061751206ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GATM FAXC RETSAT SPECC1 DNAH9 MAP3K19

8.31e-06176120687de432c680b80555342afac864599bbc002c040
ToppCellCOPD-Myeloid-DC_Mature|World / Disease state, Lineage and Cell class

MAP3K14 SPECC1 SULF2 ANTXR2 NAV1 UVRAG

9.75e-061811206675603a401d92cf9fdcd44e211ec899fa86a0d49
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT4 ABCA3 MAP3K14 LIFR SULF2 HMCN1

1.01e-051821206f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

MAP3K14 SPECC1 SULF2 SLC24A4 NAV1 UVRAG

1.04e-051831206703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT2 H6PD RETSAT F5 MIA2 FGFR4

1.04e-051831206d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

MAP3K14 SPECC1 SULF2 SLC24A4 NAV1 UVRAG

1.04e-051831206b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDCA3 PRUNE2 CHAF1A SULF2 MKI67 KIF18B

1.10e-05185120657c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF3 ABCA9 THBS2 NAV1 KIAA1755 ADGRD1

1.10e-0518512068f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell(3)_DC_1|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ZMYND15 NCKAP5 LGALS9 SULF2 SLC24A4 TCHHL1

1.21e-051881206ee616d14e060385ee55e4cd5b60218e9374c6065
ToppCellCOPD-Myeloid-DC_Mature|COPD / Disease state, Lineage and Cell class

MAP3K14 SPECC1 SULF2 ANTXR2 NAV1 UVRAG

1.21e-051881206de93ccb53edb8599da9e312db0e3af604c21f673
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF3 ABCA9 THBS2 ANTXR2 KIAA1755 ADGRD1

1.21e-051881206fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SH3BGRL MAP3K14 GATM SPECC1 FCGRT NAV1

1.21e-0518812065e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCellIPF-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

MAP3K14 SPECC1 SULF2 ANTXR2 NAV1 UVRAG

1.25e-05189120649e67d298d045f29136919b7d9971b6502b0efaa
ToppCell(3)_DC_activated|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MAP3K14 SPECC1 LGALS9 SULF2 NAV1 UVRAG

1.25e-051891206e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 THBS2 ANTXR2 ENAH ADGRD1

1.28e-0519012062e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 ANTXR2 KIAA1217 ENAH ADGRD1

1.28e-0519012062306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 THBS2 ANTXR2 ENAH ADGRD1

1.28e-0519012060028f886c789ba238c031eae5d96acaed4af8c25
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 ANTXR2 KIAA1217 ENAH ADGRD1

1.28e-0519012061f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SH3BGRL H6PD ENAH NAV2 FGFR3 FGFR4

1.32e-051911206e7c605b56934d1383237c1f946dbccef25d91368
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 KIAA1217 NAV2

1.32e-05191120639092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 ENAH KIAA1755

1.32e-051911206107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 ENAH KIAA1755

1.32e-051911206bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 KIAA1217 NAV2

1.32e-051911206ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 KIAA1217 NAV2

1.36e-0519212065105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellCOPD-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

MAP3K14 SPECC1 SULF2 ANTXR2 NAV1 UVRAG

1.36e-051921206baebd462f464e7d0e462d07a74bb5d685a9fc3b6
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRUNE2 FILIP1 SH3BGRL FAXC ENAH NAV2

1.36e-051921206d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP3K14 SPECC1 SULF2 ANTXR2 NAV1 UVRAG

1.40e-0519312067426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCKAP5 LIFR ANTXR2 HMCN1 KIAA1217 NAV1

1.40e-051931206e1d546165dcc2392f540162206852c4717d7306f
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAP3K14 SPECC1 SULF2 ANTXR2 NAV1 UVRAG

1.40e-051931206a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 ANTXR2 KIAA1217 NAV2

1.44e-05194120681713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GATM NCKAP5 SPECC1 LGALS9 SULF2 NAV1

1.44e-051941206b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GATM NCKAP5 SPECC1 LGALS9 SULF2 NAV1

1.44e-0519412062210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EBF3 ABCA9 THBS2 NAV2 NAV1 ADGRD1

1.44e-051941206c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 KIAA1217 NAV2

1.44e-051941206cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 ANTXR2 KIAA1217 ENAH

1.44e-05194120690efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 KIAA1217 NAV2

1.44e-051941206e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 ANTXR2 KIAA1217 ENAH

1.44e-051941206df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 ABCA9 THBS2 ANTXR2 KIAA1217 NAV2

1.44e-051941206ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EBF3 DACT2 GATM LIFR NAV2 EGFLAM

1.44e-051941206c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 ANTXR2 KIAA1217 NAV2

1.44e-051941206627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GATM NCKAP5 ABCA9 ANTXR2 FCGRT NAV2

1.49e-0519512064008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA9 THBS2 ANTXR2 NAV2 NAV1 ADGRD1

1.49e-0519512063c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellCOPD-Stromal-Myofibroblast|COPD / Disease state, Lineage and Cell class

FILIP1 THBS2 HMCN1 ENAH NAV2 FGFR4

1.53e-051961206af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SH3BGRL H6PD ENAH NAV2 FGFR3 FGFR4

1.53e-05196120654f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 SPECC1 ABCA9 ANTXR2 KIAA1217 ENAH

1.53e-0519612062b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellControl-Myeloid-cDC|Control / Disease group, lineage and cell class

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1

1.53e-05196120685d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCellhealthy_donor-Myeloid-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1

1.53e-051961206ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCellBronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLT4 GATM SPECC1 DZIP3 RPUSD2 NLE1

1.53e-051961206bbdc92ec2e95ed7d782df0c72d94f9a9d9439bf0
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

SHROOM3 SYT17 KIAA1217 ENAH NAV2 DNAH9

1.53e-05196120687d9881cfec461a5d89b688a83749b618c519485
ToppCellhealthy_donor-Myeloid-Dendritic-cDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1

1.53e-051961206aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCellmetastatic_Lymph_Node-Fibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

DACT2 ABCA9 THBS2 HMCN1 KIAA1755 EGFLAM

1.53e-051961206275e153347caf94edc0c50021bbab49c8696fecb
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

FILIP1 SHROOM3 GATM THBS2 MKI67 FGFR3

1.58e-05197120661749ccafeb938c310cff1de5ff924a1c794325a
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

FILIP1 THBS2 HMCN1 ENAH NAV2 FGFR4

1.58e-051971206d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCellHealthy_donor-cDC|Healthy_donor / disease group, cell group and cell class (v2)

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1

1.58e-051971206b57a27e5b855bbdd1dfa352540599d260dc482aa
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

FILIP1 SHROOM3 GATM THBS2 MKI67 FGFR3

1.58e-0519712069d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellHealthy/Control-cDC|World / Disease group and Cell class

GATM NCKAP5 SULF2 FCGRT NAV1 KCNQ1

1.58e-0519712064497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCellHealthy/Control-cDC|Healthy/Control / Disease group and Cell class

NCKAP5 SPECC1 SULF2 FCGRT NAV1 KCNQ1

1.58e-051971206926423aae9fcf654f84b0f7621103a6a22d3aced
ToppCellHealthy_donor-cDC|World / disease group, cell group and cell class (v2)

NCKAP5 SPECC1 LGALS9 SULF2 FCGRT NAV1

1.58e-051971206a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDCA3 MKI67 DZIP3 NAV2 KIF18B BORA

1.62e-051981206c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

FLT4 NCKAP5 LIFR HMCN1 KIAA1217 EGFLAM

1.67e-05199120611c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellCaecum-(5)_Dendritic_cell-(51)_cDC1|Caecum / shred on region, Cell_type, and subtype

ZMYND15 NCKAP5 LGALS9 SULF2 SLC24A4 NAV1

1.67e-0519912062b97fda45241b2ce7be904cf081cabcf3eb5ba1d
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FOLH1 DACT2 GRIK1 ABCA9 THBS2 KIAA1755

1.67e-0519912066e8a44e46b46e87b81dbfc56fcbbcde166fd00fe
ToppCell(5)_Dendritic_cell|World / shred on Cell_type and subtype

ZMYND15 NCKAP5 LGALS9 SULF2 MKI67 NAV1

1.67e-051991206495de74a918c5c625a2d0ef120fe4162d4ce6e76
ToppCellCaecum-Dendritic_cell-cDC1|Caecum / Region, Cell class and subclass

ZMYND15 NCKAP5 LGALS9 SULF2 SLC24A4 NAV1

1.67e-0519912069ab38a0060a883de6fe3da8cdac42e124d7981d9
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLF1 NCKAP5 LIFR HMCN1 KIAA1217 PCNT

1.72e-052001206dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellCaecum-Dendritic_cell|Caecum / Region, Cell class and subclass

ZMYND15 NCKAP5 LGALS9 SULF2 SLC24A4 MKI67

1.72e-052001206b91d3d7505a022ca360ab5b3f9955753d111f974
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

CDCA3 DDIAS MKI67 NAV2 KIF18B BORA

1.72e-0520012069bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellControl-Control-Myeloid-cDC|Control / Disease, condition lineage and cell class

SPECC1 LGALS9 SULF2 FCGRT NAV1 UVRAG

1.72e-0520012061375d199320feb85ba06e74b10df6521e790addf
ToppCellCOVID-19-COVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease, condition lineage and cell class

SPECC1 LGALS9 SULF2 FCGRT NAV1 UVRAG

1.72e-052001206e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA9 THBS2 HMCN1 NAV2 NAV1 ADGRD1

1.72e-052001206b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellCaecum-(5)_Dendritic_cell|Caecum / shred on region, Cell_type, and subtype

ZMYND15 NCKAP5 LGALS9 SULF2 SLC24A4 MKI67

1.72e-052001206aa87810706fd4164085d8e973359b68a2691842e
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CDCA3 DDIAS MKI67 KIF18B BORA

2.82e-051311205f9fb8d74ca720b81fd5910cc975510359a8ef751
Diseasecerebral palsy (implicated_via_orthology)

AGAP7P AGAP4 AGAP6

6.78e-06101153DOID:1969 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ABCA1 ABCA3 ELOA2 FOLH1 F5 ABCA9 LIFR CFAP77 MKI67 FGFR3 PLPPR2 CUX1

1.98e-0570211512C0009402
Diseasebone disease (implicated_via_orthology)

FGFR3 FGFR4

1.49e-0451152DOID:0080001 (implicated_via_orthology)
Diseasecortical surface area measurement

FILIP1 SHROOM3 CHAF1A MAP3K14 TRIOBP NCKAP5 RETSAT SULF2 NAV2 NAV1 KIAA1755 ACTL6B FGFR3 MAP3K7 CUX1

2.34e-04134511515EFO_0010736
Diseasearteriosclerosis (implicated_via_orthology)

LIPE MAP3K7

3.12e-0471152DOID:2349 (implicated_via_orthology)
Diseasexerostomia

SHROOM3 EGFLAM

4.15e-0481152EFO_0009869
Diseasevenous thromboembolism, response to antineoplastic agent

ANTXR2 SLC24A4 RIC1

5.52e-04411153EFO_0004286, GO_0097327
Diseaseuric acid measurement

ABCA1 SHROOM3 FLT4 F5 DDX1 CRB1 NAV1 KCNQ1 PRRC2B

6.56e-046101159EFO_0004761
Diseasehigh grade glioma (implicated_via_orthology)

MKI67 FGFR3 FGFR4

6.80e-04441153DOID:3070 (implicated_via_orthology)
Diseaselip morphology measurement

YTHDC2 CRB1 DNAH1 KCNQ1 AGAP6

8.88e-041891155EFO_0007845
Diseaseurinary nitrogen measurement

SPECC1 TUBGCP6

1.33e-03141152EFO_0005190
Diseasecortical thickness

SHROOM3 CHAF1A TRIOBP NCKAP5 SPECC1 SULF2 SMG7 NAV2 NAV1 KIAA1755 FGFR3 MAP3K7

1.36e-03111311512EFO_0004840
Diseaseurate measurement, spine bone mineral density

CEP89 NAV2 RIC1

1.52e-03581153EFO_0004531, EFO_0007701
DiseaseSitus ambiguus

SHROOM3 DNAH9

1.53e-03151152C0266642
Diseasecreatinine measurement

GAPVD1 SHROOM3 SPEG MAP3K14 GATM DDX1 CEP89 KCNQ1 KIAA1755 FGFR4 CUX1

1.78e-0399511511EFO_0004518
Diseasechronic kidney disease

SHROOM3 GATM SLC24A4 CEP89 KCNQ1

2.32e-032351155EFO_0003884
Diseaseserum homoarginine measurement

GATM KCNQ1

2.73e-03201152EFO_0005421
Diseasekidney disease (biomarker_via_orthology)

GATM MKI67

3.01e-03211152DOID:557 (biomarker_via_orthology)
Diseaseosteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty

FGFR3 CUX1

3.01e-03211152EFO_0004616, EFO_0010726, EFO_1000786
Diseaseatrial fibrillation

FILIP1 SULF2 SLC24A4 NAV2 KIAA1755 HERC1

3.39e-033711156EFO_0000275
Diseaseerythrocyte measurement

CHAF1A SPECC1 ABCA7 CCDC27 LUC7L

3.40e-032571155EFO_0005047
DiseaseDisproportionate short stature

LIFR FGFR3 PCNT

3.42e-03771153C0878659

Protein segments in the cluster

PeptideGeneStartEntry
TPTPVCKRSMRWSNL

AGAP4

216

Q96P64
WSGSNMKSPPVERSH

CCDC61

451

Q9Y6R9
VLSGKWPSSRRSQEM

CHD8

2171

Q9HCK8
LLLWRGDSPMRPNSD

EGFLAM

876

Q63HQ2
MPEARSSGPDLTRWR

CFAP77

1

Q6ZQR2
GTRPGMASTKLSPWD

ADGRD1

846

Q6QNK2
MPRWVPDRAFSRTKD

ADCY6

581

O43306
GSVSDMLSRPKPWSK

CUX1

976

P39880
SAPFLKGRTIMGWPD

ABCA9

96

Q8IUA7
PVLMSEAPWNTRAKR

ACTL6B

116

O94805
KWSMERLQAPPRPET

GRIK1

296

P39086
TSNGRLPVKWMAPEA

FGFR4

646

P22455
PTTGMDPKARRFLWN

ABCA1

2071

O95477
MVAERSPARSPGSWL

ANTXR2

1

P58335
MRSAAKPWNPAIRAG

SPECC1

1

Q5M775
PSTGMDPVARRLLWD

ABCA3

1541

Q99758
SSRKGRQRSMVWPGD

GIT2

606

Q14161
VEMLPGKRWLSSQPS

CCNT1

326

O60563
TSGPRMCPRKEQDSW

CHAF1A

211

Q13111
EPTTGMDPSARRFLW

ABCA7

1951

Q8IZY2
TPTPVCKRSMRWSNL

AGAP6

216

Q5VW22
ETPRSSGSMRNRWKP

CDCA3

176

Q99618
QSMASRDARCPEWKP

CCDC27

71

Q2M243
PDTWRNRKLMAPVNG

SLC24A4

56

Q8NFF2
RGPTPRTEEAAWAAM

TP53I13

301

Q8NBR0
LSMPSGPSGKRWSKD

RIC1

1036

Q4ADV7
ALGRQPSSALSWMPE

NOBOX

636

O60393
QDGMPGRSWASKRVS

PARP2

66

Q9UGN5
MWSQRDPSLRKSGVG

PABPC1L2A

76

Q5JQF8
LAQAMWTLPGTRPER

FAXC

296

Q5TGI0
ETPRMPSWASARDRQ

ELOA2

261

Q8IYF1
WSRINPNKARIPMAG

PARP15

266

Q460N3
MAAASSPPRAERKRW

KCNQ1

1

P51787
PPDWRLESSNGKMAS

LUC7L

346

Q9NQ29
SWILSPSSMSEPRRG

PSMG3-AS1

126

Q96PY0
SNSTDTLWRPMPKLA

MGA

2976

Q8IWI9
RGAKWTTAPKPTMAD

GATM

206

P50440
SKGRWDQPPLDSLGM

KIAA1755

1086

Q5JYT7
NSWGSEERSLPRKMP

LGALS9C

286

Q6DKI2
NSWGSEERSLPRKMP

LGALS9B

286

Q3B8N2
SWGSEERSLPRKMPF

LGALS9

286

O00182
LEKMGGSAPPDSSWR

FOLH1

306

Q04609
VSSVRRPMSDPSWNR

GAPVD1

906

Q14C86
RPMSDPSWNRRPGNE

GAPVD1

911

Q14C86
GPDRWESLSKGQRMQ

HERC1

871

Q15751
AKDNTRPGANSPEMW

DDX1

471

Q92499
RPGANSPEMWSEAIK

DDX1

476

Q92499
MADQLRKPPSRDQWS

ECE2

586

P0DPD6
ERGRGNLEWKEPPSM

FCGRT

191

P55899
KLPPGWEKRMSRSSG

PIN1

6

Q13526
SPNRSTNTLKEMPWG

DDIAS

641

Q8IXT1
SLMTRCWSKDPSQRP

MAP3K7

261

O43318
LGESVSDMAPARPRW

TUBGCP6

1171

Q96RT7
GTGMERWPRTPKEEA

MKI67

2056

P46013
TPAQGSRWPMEKKRR

KIF18B

616

Q86Y91
SSRMLQPSSSPLWGK

NOC2L

231

Q9Y3T9
PRKSPVGMLDLSSWS

PCNT

2211

O95613
PSAGLRSDPSIMNWE

DZIP3

1021

Q86Y13
GNPIPERRWIKNSAM

HMCN1

916

Q96RW7
AEAQRPWRDGLLMPS

PTPN21

781

Q16825
RRLSPWEDLGQAPTM

PLPPR2

296

Q96GM1
GKPFRLMWSQPDDRL

PABPC5

86

Q96DU9
LSMGGTWASKEPLRP

CGB2

11

Q6NT52
SREAPPWENSSMRGL

GAK

716

O14976
QWALSTPRMRKGPSV

DNAH1

416

Q9P2D7
TRPSKALWPAQMSAA

LINC00482

76

Q8N8I6
MASSPIQPRKGGADW

FBF1

331

Q8TES7
GRVEMRKWSSEPGPE

KLHL11

136

Q9NVR0
KARPSMGDWRPRSVD

DACT2

166

Q5SW24
TSQLRPRPNWQSEMG

CEP89

96

Q96ST8
PRPNWQSEMGRRSSL

CEP89

101

Q96ST8
EPSRTWARGRMDTQP

GAS2L1

626

Q99501
WARGRMDTQPDRKPS

GAS2L1

631

Q99501
IDGCSPIKNWSPMRL

BORA

321

Q6PGQ7
EPTTGMDPKARRFLW

ABCA2

2211

Q9BZC7
TPTPVCKRSMRWSNL

AGAP7P

216

Q5VUJ5
EPTRKPWERTNTMNG

ENAH

491

Q8N8S7
MAPRGRVPKDRSWKA

DNAH9

3196

Q9NYC9
TTNGRLPVKWMAPEA

FGFR3

651

P22607
KEEPLGSGMNPVRSW

EBF3

16

Q9H4W6
WLERGRLAMLTPNSP

CRB1

766

P82279
RNLFRPSLPSSWKEM

H6PD

416

O95479
SSPGTMLKTWARLQP

DHX37

1086

Q8IY37
LKSMWPLPSATQRRA

FAM86C2P

116

A6NEL3
WRGSTPKEMGRETTK

MAP3K19

1006

Q56UN5
RSHMKDSSGNWREPP

NTAQ1

146

Q96HA8
RSEPCLMDWRKVPSN

LIFR

666

P42702
MEPGSKSVSRSDWQP

LIPE

1

Q05469
SWNMVLARGRPTDTP

MAP3K14

841

Q99558
GSLSPPWDQDRRMMF

MIA2

1201

Q96PC5
LKMEPGTSKWRRERP

NAV1

491

Q8NEY1
KDPTWEDRFPGRSTM

RETSAT

446

Q6NUM9
RPSFTRTWSGDKGPM

RPUSD2

21

Q8IZ73
WSPAEDKKPLTRMTG

NLE1

356

Q9NVX2
NPTWRSLDFGIMPDR

UVRAG

91

Q9P2Y5
EKWSTSRPGMGLRRN

TMC3

451

Q7Z5M5
PSVRDPNEWAMAKSG

PRUNE2

826

Q8WUY3
QTPPWLMASRSSDKD

SYT17

56

Q9BSW7
PSQDTGSPSRMRPWK

F5

911

P12259
PWMRKRENGPSITQE

FILIP1

871

Q7Z7B0
SRMPSRRDWVQCPKS

NCKAP5

876

O14513
RTADRWKTDKPAMGG

SMG7

1041

Q92540
SGIKMEPGSKWRRNP

NAV2

1021

Q8IVL1
RKWMRENVPENSRPA

SH3BGRL

46

O75368
GRDRLGPLKMSDSTW

SETD9

201

Q8NE22
RPSDPPKWERGMENS

KIAA1217

1211

Q5T5P2
PREPSSWGARAGKSM

SHROOM3

1206

Q8TF72
MESSRWDKDPPGERR

DIP2C-AS1

1

Q8N8Z3
PLKGRLVTSWRMPGD

TRIOBP

1741

Q9H2D6
EVRMRRWSKTASPPV

nan

71

Q8TAT8
PFPGTIKSRDMSWKR

STK19

101

P49842
LGPWVMAARSKDAAP

ZNF394

16

Q53GI3
GRMVTLTWNPPRSLD

SPEG

1296

Q15772
LMQLCWSSEPKDRPS

RIPK3

261

Q9Y572
PSKMRTWVQSQGPRS

ZSCAN1

91

Q8NBB4
RIMLNCWSGDPKARP

FLT4

1146

P35916
SGNFLPPSWRKLMSD

XRN2

606

Q9H0D6
PPSWRKLMSDPDSSI

XRN2

611

Q9H0D6
RESSDVPPMKRNNWI

PRRC2B

1036

Q5JSZ5
KQWMPPRSNRFTAEE

RHPN2P1

406

A8MT19
SPQMQSAPKRWREEL

SLF1

101

Q9BQI6
RRMRAPSKPWSQVDE

YTHDC2

1136

Q9H6S0
PPKTRNMSACWQDGR

THBS2

311

P35442
WTVGTSPTQEKRMLP

TCHHL1

121

Q5QJ38
RLWPMQARSNGTKRP

USP7

621

Q93009
GVKLAKTPMRTWGPR

ZMYND15

286

Q9H091
PEMKRPSSKSLGQLW

SULF2

851

Q8IWU5
WKSMPRLPTDLDIGG

USP6

451

P35125