Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentdendritic spine membrane

TRPV1 AKAP5

1.06e-0418182GO:0032591
GeneOntologyCellularComponentdendrite membrane

TRPV1 AKAP5

1.05e-0356182GO:0032590
Domainzf-C2H2

ZNF729 ZNF99 ZNF518A ZNF254

3.04e-03693174PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF729 ZNF99 ZNF518A ZNF254

3.06e-03694174IPR013087
DomainKRAB

ZNF729 ZNF99 ZNF254

3.89e-03358173PS50805
DomainKRAB

ZNF729 ZNF99 ZNF254

3.89e-03358173PF01352
DomainKRAB

ZNF729 ZNF99 ZNF254

4.23e-03369173SM00349
DomainKRAB

ZNF729 ZNF99 ZNF254

4.27e-03370173IPR001909
DomainZINC_FINGER_C2H2_2

ZNF729 ZNF99 ZNF518A ZNF254

4.54e-03775174PS50157
DomainZINC_FINGER_C2H2_1

ZNF729 ZNF99 ZNF518A ZNF254

4.58e-03777174PS00028
DomainZnf_C2H2-like

ZNF729 ZNF99 ZNF518A ZNF254

5.00e-03796174IPR015880
DomainZnf_C2H2

ZNF729 ZNF99 ZNF518A ZNF254

5.20e-03805174IPR007087
DomainZnF_C2H2

ZNF729 ZNF99 ZNF518A ZNF254

5.27e-03808174SM00355
DomainAnk

ANKRD62 TRPV1

1.79e-02228172PF00023
Domain-

ANKRD62 TRPV1

2.09e-022481721.25.40.20
DomainANK

ANKRD62 TRPV1

2.14e-02251172SM00248
DomainANK_REPEAT

ANKRD62 TRPV1

2.17e-02253172PS50088
DomainAnkyrin_rpt-contain_dom

ANKRD62 TRPV1

2.19e-02254172IPR020683
DomainANK_REP_REGION

ANKRD62 TRPV1

2.19e-02254172PS50297
Domain-

ZNF729 ZNF99 ZNF254

2.22e-026791733.30.160.60
DomainAnkyrin_rpt

ANKRD62 TRPV1

2.32e-02262172IPR002110
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF729 ZNF99 ZNF254

5.28e-081518315885501
Pubmed

Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia.

TRPV1 AKAP5

2.53e-07218223616546
Pubmed

Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.

TRPV1 AKAP5

2.53e-07218223264624
Pubmed

Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.

TRPV1 AKAP5

2.53e-07218223699529
Pubmed

Selective activation of AKAP150/TRPV1 in ventrolateral periaqueductal gray GABAergic neurons facilitates conditioned place aversion in male mice.

TRPV1 AKAP5

2.53e-07218237460788
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF729 ZNF99 ZNF254

4.22e-072918314563677
Pubmed

Sensitization of glutamate receptor-mediated pain behaviour via nerve growth factor-dependent phosphorylation of transient receptor potential V1 under inflammatory conditions.

TRPV1 AKAP5

7.59e-07318232579702
Pubmed

Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.

TRPV1 AKAP5

7.59e-07318218463244
Pubmed

Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150.

TRPV1 AKAP5

5.30e-06718218701070
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF729 ZNF99

1.14e-051018218588511
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF729 ZNF99

1.39e-051118215469996
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF729 ZNF99

1.97e-051318219850934
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF729 ZNF99

2.93e-04491829630514
InteractionTRPV2 interactions

TRPV1 AKAP5

3.38e-0510182int:TRPV2
Cytoband19p12

ZNF729 SUGP2 ZNF99 ZNF254

4.14e-089018419p12
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF729 ZNF99 ZNF254

1.45e-05122183chr19p12
CytobandEnsembl 112 genes in cytogenetic band chr11p15

PIK3C2A NLRP14

2.02e-02564182chr11p15
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF729 ZNF99 ZNF518A ZNF254

1.79e-0371814428
GeneFamilyAnkyrin repeat domain containing

ANKRD62 TRPV1

1.46e-02242142403
CoexpressionBONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING

TMEM168 SUGP2 CYRIA VAV2 ZNF518A

1.83e-05506185M253
ComputationalGenes in the cancer module 279.

CYRIA VAV2 DDX18 AKAP5

1.91e-0614184MODULE_279
ComputationalGenes in the cancer module 334.

CYRIA VAV2 DDX18 AKAP5

3.66e-0616684MODULE_334

Protein segments in the cluster

PeptideGeneStartEntry
KCYCERLKVKFQKMK

ANKRD62

436

A6NC57
AFCKTSKIDMKGCIK

CYRIA

271

Q9H0Q0
MAAFCRSITKLKTKF

PIK3C2A

381

O00443
KKNRKKKLMVFFSSC

DDX18

421

Q9NVP1
AFKKSFKLCVTKEML

MFSD11

226

O43934
KASMLCFKRRKKAAK

AKAP5

31

P24588
MAFLTCCLLKCVKKS

SUSD3

121

Q96L08
FCRKCKKLSKSEMHR

CCDC110

336

Q8TBZ0
RHTKKKTFKCMKCSK

ZNF99

166

A8MXY4
KTFKCMKCSKSFFML

ZNF99

171

A8MXY4
CSKCKKMVPASKRFT

USP42

291

Q9H9J4
KSFLKCMRKAFRSGK

TRPV1

711

Q8NER1
TCAKMLASFKCSLKP

SUGP2

361

Q8IX01
CKTCFRCLKRLKMSW

TMEM168

666

Q9H0V1
KMSAKILNFSCLKCR

ZNF518A

111

Q6AHZ1
FDKTTNCKACKMFLR

VAV2

531

P52735
SFKCKKRVKLFCMLS

ZNF254

181

O75437
KCIKCSKSFFMLSCL

ZNF729

181

A6NN14
RTFNCKMSLKIKSKL

NLRP14

546

Q86W24