Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionMHC class Ib protein binding

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.00e-06161184GO:0023029
GeneOntologyMolecularFunctionMHC class Ib receptor activity

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

4.19e-06191184GO:0032394
GeneOntologyMolecularFunctionMHC class I receptor activity

KIR2DS5 KIR3DL1 KIR3DS1

1.54e-04181183GO:0032393
GeneOntologyMolecularFunctionMHC protein binding

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

3.84e-04581184GO:0042287
GeneOntologyMolecularFunctionimmune receptor activity

KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

4.47e-041651186GO:0140375
GeneOntologyMolecularFunctionsingle-stranded DNA 3'-5' DNA exonuclease activity

EXO5 POLE

5.11e-0461182GO:0008310
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

5.11e-0461182GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

9.47e-0481182GO:0032453
GeneOntologyMolecularFunctionmolecular adaptor activity

SHANK1 NPM1 DLGAP2 ANK3 KAT6A LRRK2 OBSL1 TRIM21 SKI SFMBT2 LIAT1 ZAR1 KIR3DL3 PHF14 KIR2DL1 KIR2DL3 KIR3DL1 TP53BP1

9.99e-04135611818GO:0060090
DomainRIBOSOMAL_S4E

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163PS00528
DomainRibosomal_S4e_central_region

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163IPR013845
DomainRibosomal_S4e_N

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163IPR013843
DomainRibosomal_S4e_central

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163PD002667
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163PF16121
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163IPR032277
DomainRibosomal_S4e_N_CS

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163IPR018199
DomainRS4NT

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163PF08071
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163IPR000876
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

2.33e-0731163PF00900
DomainZF_PHD_1

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF20L1 PHF14

2.24e-06961167PS01359
DomainS4

RPS4Y2 RPS4X RPS4Y1

2.31e-0651163SM00363
DomainS4

RPS4Y2 RPS4X RPS4Y1

2.31e-0651163PS50889
Domainig

DSCAM OBSL1 KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.89e-061901169PF00047
DomainImmunoglobulin

DSCAM OBSL1 KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.89e-061901169IPR013151
DomainZinc_finger_PHD-type_CS

KDM5C KDM5D PHF21A TRIM66 PHF20L1 PHF14

3.09e-06651166IPR019786
DomainS4_RNA-bd

RPS4Y2 RPS4X RPS4Y1

4.61e-0661163IPR002942
DomainPHD

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF14

7.16e-06751166PF00628
DomainZnf_PHD-finger

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF14

9.68e-06791166IPR019787
DomainPHD

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF14

1.92e-05891166SM00249
DomainZnf_PHD

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF14

2.19e-05911166IPR001965
DomainZF_PHD_2

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF14

2.79e-05951166PS50016
DomainZnf_FYVE_PHD

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF20L1 PHF14

3.70e-051471167IPR011011
DomainKOW

RPS4Y2 RPS4X RPS4Y1

3.71e-05111163IPR005824
DomainKOW

RPS4Y2 RPS4X RPS4Y1

3.71e-05111163PF00467
DomainNPIP

NPIPB3 NPIPB5 NPIPB13

8.08e-05141163IPR009443
DomainTscrpt_reg_SKI_SnoN

SKI SKOR1

2.28e-0441162IPR023216
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

2.28e-0441162IPR013637
Domainc-SKI_SMAD_bind

SKI SKOR1

2.28e-0441162PF08782
DomainFAM47

FAM47A FAM47C

2.28e-0441162PF14642
DomainS4

RPS4X RPS4Y1

2.28e-0441162PF01479
Domainc-SKI_SMAD_bind

SKI SKOR1

2.28e-0441162SM01046
Domainc-SKI_SMAD4-bd_dom

SKI SKOR1

2.28e-0441162IPR014890
DomainPLU-1

KDM5C KDM5D

2.28e-0441162PF08429
DomainFAM47

FAM47A FAM47C

2.28e-0441162IPR032743
DomainIG

DSCAM OBSL1 KIR2DS2 KIR3DL3 KIR2DL1 MYBPHL KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.96e-0442111610SM00409
DomainIg_sub

DSCAM OBSL1 KIR2DS2 KIR3DL3 KIR2DL1 MYBPHL KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.96e-0442111610IPR003599
Domainzf-C5HC2

KDM5C KDM5D

3.78e-0451162PF02928
DomainZnf_C5HC2

KDM5C KDM5D

3.78e-0451162IPR004198
Domain-

KDM5C KAT6A TRIM21 KDM5D RNF43 PHF21A TRIM45 TRIM66 PHF20L1 PHF14

4.91e-04449116103.30.40.10
DomainZnf_RING/FYVE/PHD

KDM5C KAT6A TRIM21 KDM5D RNF43 PHF21A TRIM45 TRIM66 PHF20L1 PHF14

5.83e-0445911610IPR013083
DomainSki_Sno

SKI SKOR1

7.87e-0471162PF02437
Domain-

SKI SKOR1

7.87e-04711623.10.260.20
DomainTransform_Ski

SKI SKOR1

7.87e-0471162IPR003380
DomainBBOX

TRIM21 MEFV TRIM45 TRIM66

8.95e-04691164SM00336
Domain-

TRIM21 MEFV TRIM45 TRIM66

9.96e-047111644.10.45.10
Domainzf-B_box

TRIM21 MEFV TRIM45 TRIM66

1.05e-03721164PF00643
DomainZU5

ANK3 TJP1

1.34e-0391162SM00218
DomainZF_BBOX

TRIM21 MEFV TRIM45 TRIM66

1.55e-03801164PS50119
DomainZnf_B-box

TRIM21 MEFV TRIM45 TRIM66

1.63e-03811164IPR000315
DomainMBT

SFMBT2 PHF20L1

1.67e-03101162PF02820
DomainJmjN

KDM5C KDM5D

1.67e-03101162SM00545
DomainMbt

SFMBT2 PHF20L1

1.67e-03101162IPR004092
DomainJmjN

KDM5C KDM5D

1.67e-03101162PF02375
DomainJMJN

KDM5C KDM5D

1.67e-03101162PS51183
DomainZU5

ANK3 TJP1

1.67e-03101162PS51145
DomainAnk_3

ANK3 ASB2

1.67e-03101162PF13606
DomainJmjN

KDM5C KDM5D

1.67e-03101162IPR003349
DomainSH3_2

SHANK1 DOCK4 TJP1 SH3D19

2.03e-03861164PF07653
DomainSH3_2

SHANK1 DOCK4 TJP1 SH3D19

2.03e-03861164IPR011511
DomainDNA-bd_dom_put

SKI SKOR1

2.03e-03111162IPR009061
Domain-

SKI SKOR1

2.42e-031211623.10.390.10
DomainZU5

ANK3 TJP1

2.42e-03121162PF00791
DomainZU5_dom

ANK3 TJP1

2.42e-03121162IPR000906
DomainSAND_dom-like

SKI SKOR1

2.42e-03121162IPR010919
DomainIG_LIKE

DSCAM OBSL1 KIR2DS2 KIR3DL3 KIR2DL1 MYBPHL KIR2DL3 KIR2DS5 KIR3DL1

3.55e-034911169PS50835
DomainBbox_C

TRIM45 TRIM66

3.81e-03151162IPR003649
Domain-

KDM5C KDM5D

3.81e-031511621.10.150.60
DomainBBC

TRIM45 TRIM66

3.81e-03151162SM00502
DomainBRIGHT

KDM5C KDM5D

3.81e-03151162SM00501
DomainARID_dom

KDM5C KDM5D

3.81e-03151162IPR001606
DomainARID

KDM5C KDM5D

3.81e-03151162PS51011
DomainARID

KDM5C KDM5D

3.81e-03151162PF01388
DomainIg-like_dom

DSCAM OBSL1 KIR2DS2 KIR2DL1 MYBPHL KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

4.15e-035031169IPR007110
DomainIg-like_fold

DSCAM OBSL1 KIR2DS2 TRIM45 KIR3DL3 KIR2DL1 MYBPHL KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

4.49e-0370611611IPR013783
Domain-

SHANK1 ANK3 TRPC5 LRRK2 SNCAIP ASB2

4.54e-0324811661.25.40.20
DomainANK_REPEAT

SHANK1 ANK3 TRPC5 MUC16 SNCAIP ASB2

5.00e-032531166PS50088
DomainAnkyrin_rpt-contain_dom

SHANK1 ANK3 TRPC5 LRRK2 SNCAIP ASB2

5.10e-032541166IPR020683
DomainANK_REP_REGION

SHANK1 ANK3 TRPC5 MUC16 SNCAIP ASB2

5.10e-032541166PS50297
DomainAnkyrin_rpt

SHANK1 ANK3 TRPC5 LRRK2 SNCAIP ASB2

5.91e-032621166IPR002110
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

4.81e-1512124717490516
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.07e-1414124719875891
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.07e-1414124715896204
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.88e-1415124720082646
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.88e-1415124720356536
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.88e-1415124719926642
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.88e-1415124720643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.88e-1415124719326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124719897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124719000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124720670355
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124718668235
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124719309280
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124719527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124720652381
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124719279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124717868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124718643961
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124720331834
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.87e-1416124720210919
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124719968064
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124720878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124720650299
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124720173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124720483367
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124719218127
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124719169284
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124719450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.16e-1317124719761533
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.90e-1318124719630074
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.90e-1318124719046302
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.90e-1318124720580654
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.90e-1318124720519398
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.90e-1318124719846535
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.90e-1318124720210918
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.00e-1319124718571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.00e-1319124718778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.00e-1319124720600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of ParanĂ¡.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.00e-1319124718848853
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

4.60e-1320124720193031
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.88e-1321124719861144
Pubmed

Natural killer cells and immune surveillance.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

8.28e-1311124618830515
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

8.28e-1311124619664392
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.01e-1222124720492596
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.65e-1212124620371502
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.65e-1212124619936734
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.65e-1212124619181658
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.65e-1212124620137308
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.06e-1213124619934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.06e-1213124619120281
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.06e-1213124618687225
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1 KIR3DS1

5.33e-1214124619489269
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

5.33e-1214124619421224
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DS5 KIR3DL1 KIR3DS1

5.33e-1214124618945962
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

8.86e-1215124619850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

8.86e-1215124620207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

8.86e-1215124619493232
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1

8.86e-1215124617498266
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

9.02e-1229124720082482
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1

1.41e-1116124616403292
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.18e-1117124619032228
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DS1

2.18e-1117124620173784
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1

3.26e-1118124620200544
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.82e-1135124719683555
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1

6.62e-11912457749980
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

6.62e-11912458662091
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DS5 KIR3DL1 KIR3DS1

6.76e-1120124620426625
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1

1.32e-1010124512559621
Pubmed

Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

KIR2DS2 KIR2DL1 KIR2DL3 KIR3DL1

7.67e-10512447716543
Pubmed

Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

5.34e-097124412618911
Pubmed

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

KIR2DS2 KIR2DL1 KIR2DS5 KIR3DL1

5.34e-097124414607943
Pubmed

Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

5.34e-097124415748957
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR2DL1 KIR2DL3 KIR3DL1 KIR3DS1

5.34e-09712449430220
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR2DS2 KIR2DL3 KIR3DL1 KIR3DS1

1.07e-088124417200871
Pubmed

A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.07e-088124415730517
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR2DL1 KIR2DL3 KIR3DL1 KIR3DS1

1.07e-08812449430221
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.07e-088124418681957
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR2DS2 KIR2DL1 KIR3DL1 KIR3DS1

1.91e-089124418340360
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR3DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.18e-0810124421206914
Pubmed

Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC.

KIR2DL1 KIR2DL3 KIR3DL1

4.42e-083124330698860
Pubmed

Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.

RPS4Y2 RPS4X RPS4Y1

4.42e-08312432124517
Pubmed

Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.

RPS4Y2 RPS4X RPS4Y1

4.42e-08312438187552
Pubmed

Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.

RPS4Y2 RPS4X RPS4Y1

4.42e-08312438808278
Pubmed

Inactivation of the Rps4 gene on the mouse X chromosome.

RPS4Y2 RPS4X RPS4Y1

4.42e-08312431783379
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

RPS4X RPS4Y1 KDM5C KDM5D

1.07e-0713124414660691
Pubmed

Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.

RPS4Y2 RPS4X RPS4Y1

1.76e-07412438139551
Pubmed

Genetic interactions of KIR and G1M immunoglobulin allotypes differ in obese from non-obese individuals with type 2 diabetes.

KIR2DL1 KIR2DL3 KIR3DL1

1.76e-074124318632158
Pubmed

Activating KIR genes are associated with ankylosing spondylitis in Asian populations.

KIR2DS5 KIR3DL1 KIR3DS1

1.76e-074124318638658
Pubmed

Polymorphism and domain variability of human killer cell inhibitory receptors.

KIR2DL3 KIR3DL1 KIR3DS1

1.76e-07412439059894
Pubmed

High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.

KIR2DL3 KIR3DL1 KIR3DS1

1.76e-074124319522772
Pubmed

NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts.

KIR2DL1 KIR2DL3 KIR3DL1

1.76e-074124327732638
Pubmed

Systemic lupus erythematosus: association with KIR and SLC11A1 polymorphisms, ethnic predisposition and influence in clinical manifestations at onset revealed by ancestry genetic markers in an urban Brazilian population.

KIR2DS2 KIR2DS5 KIR3DS1

1.76e-074124321233146
Pubmed

[Distribution of immunoglobulin like receptor gene in Han population in China and the impact thereof on the HLA-identical sibling hematopoietic stem cell transplantation].

KIR2DL1 KIR2DL3 KIR3DL1

1.76e-074124318269867
Pubmed

Study of the KIR gene profiles and analysis of the phylogenetic relationships of Rajbanshi population of West Bengal, India.

KIR2DL1 KIR2DL3 KIR3DL1

1.76e-074124323354323
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RPS4Y2 NPM1 CACNA1C C8orf88 RPS4X RPS4Y1 ACO2 NOL6 SKI SFMBT2 ADAMTS12 PHF20L1 TJP1 FAM161A NAV2 PHF14 PLCH1 PCK1 LCMT1 RPL18A

1.95e-0714421242035575683
Pubmed

Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.

RPS4Y2 RPS4X RPS4Y1

4.40e-07512439562962
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.

KIR2DS2 KIR2DL1 KIR2DL3

4.40e-075124318755860
Pubmed

Diversity of the repertoire of p58 killer cell inhibitory receptors in a single individual.

KIR2DS2 KIR2DL1 KIR2DL3

4.40e-075124310424431
Pubmed

KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer.

KIR2DL1 KIR2DL3 KIR3DL1

4.40e-075124327893413
Pubmed

Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.

RPS4Y2 RPS4X RPS4Y1

4.40e-07512437681608
InteractionKIR3DP1 interactions

KIR2DS2 KIR2DL1 KIR2DS5

8.20e-0741203int:KIR3DP1
InteractionKIR2DL2 interactions

KIR2DS2 KIR2DL1 KIR3DL1 KIR3DS1

8.20e-07131204int:KIR2DL2
InteractionTEX10 interactions

MYC NPM1 KAT6A OBSL1 COX8A PHF14 TP53BP1 RPL18A

1.01e-051751208int:TEX10
InteractionUSP15 interactions

DOCK4 NPM1 ANK3 RPS4X KAT6A LRRK2 TRIM21 RNF43 MSH6 TJP1 RORC FHL1 RPL18A

2.28e-0554612013int:USP15
InteractionYWHAQ interactions

MYC NPM1 TNK1 SH3BP2 LRRK2 OBSL1 TRIM21 RNF43 PABIR2 MEFV CEP89 TJP1 TESK2 SH3D19 NAV2 PLCH1 PCK1 MACIR DNMT1

3.30e-05111812019int:YWHAQ
InteractionSPATA1 interactions

VPS39 BICRA KDM5C PCK1

3.32e-05311204int:SPATA1
InteractionSQSTM1 interactions

MYC NPM1 CACNA1C CIP2A ACO2 CHDH KAT6A LRRK2 OBSL1 TNRC6B TRIM21 ACAD10 SKI RNF43 PHF21A ADAMTS12 TJP1 CORO7 PCK1 DNMT1

5.07e-05125712020int:SQSTM1
InteractionKIR3DL1 interactions

KIR2DS2 KIR2DL1 KIR3DL1

5.64e-05131203int:KIR3DL1
Cytoband19q13.4

KIR2DS2 LENG9 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

2.18e-0979124719q13.4
Cytoband16p12.2

NPIPB4 NPIPB3 NPIPB5

1.40e-0437124316p12.2
CytobandEnsembl 112 genes in cytogenetic band chr19q13

SHANK1 BICRA PLEKHG2 LENG9 ZNF599 LIG1 CEP89 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

4.04e-04119212411chr19q13
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

8.50e-1318817620
GeneFamilyPHD finger proteins

KDM5C KAT6A KDM5D PHF21A TRIM66 PHF20L1 PHF14

1.54e-079081788
GeneFamilySKI transcriptional corepressors

SKI SKOR1

1.18e-044812748
GeneFamilyS ribosomal proteins

RPS4Y2 RPS4X RPS4Y1

4.69e-0434813728
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM21 MEFV TRIM45 TRIM66

8.73e-049581459
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

SWAP70 RPS4Y1 KDM5D

1.55e-0351813870
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

2.00e-0315812418
GeneFamilyIntegrator complex

INTS8 INTS9

2.00e-03158121366
GeneFamilyPDZ domain containing

SHANK1 FRMPD4 TJP1 PDZD2

4.84e-031528141220
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM5D

5.13e-0324812485
CoexpressionKAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_AGE_UNKNOWN_CORRELATED_WITH_PROTECTION_56DY_NEGATIVE

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1

1.17e-07491246M40909
CoexpressionTABULA_MURIS_SENIS_PANCREAS_PANCREATIC_STELLATE_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1

8.50e-0691243MM3821
CoexpressionBILANGES_SERUM_RESPONSE_TRANSLATION

RPS4Y2 RPS4X RPS4Y1 RPL18A

2.50e-05361244MM1308
CoexpressionTABULA_MURIS_SENIS_KIDNEY_FIBROBLAST_AGEING

RPS4Y2 RPS4X RPS4Y1 RPL18A

3.45e-05391244MM3721
CoexpressionTABULA_MURIS_SENIS_THYMUS_PROFESSIONAL_ANTIGEN_PRESENTING_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1 TNRC6B RPL18A

4.20e-05811245MM3848
CoexpressionGSE14769_20MIN_VS_360MIN_LPS_BMDM_DN

SWAP70 KDM5C SH3BP2 KDM5D PHF20L1 UGT2B10 MACIR

4.80e-052001247M3513
CoexpressionGSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN

CACNA1C C12orf56 C3orf62 BRME1 MUC16 MACIR RPL18A

4.80e-052001247M6543
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

MYC NPM1 DLGAP2 LRRK2 PRAG1 RORC FHL1

7.54e-071851217c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

DOCK4 CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

8.11e-07187121792d468dde81125d51daf7abd4703741abe1ab91c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.00e-06193121799525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.04e-061941217e93de9428c986b8943fc169258847c650cfab0e5
ToppCellVE-CD4-memory_CD4|VE / Condition, Cell_class and T cell subcluster

MYC NPM1 ANK3 RPS4X RPS4Y1 RORC RPL18A

1.19e-061981217ef580576d6669ac7051e8f93fec2f2cd3887e64e
ToppCellCOVID_vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

MYC NPM1 ANK3 RPS4X RPS4Y1 TNRC6B RPL18A

1.23e-061991217885bc902b6e2af0b61e452c4154160cd3f1cf98e
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_Tcm|Leuk-UTI / Disease, condition lineage and cell class

MYC NPM1 ANK3 RPS4X RPS4Y1 RORC RPL18A

1.23e-06199121722a16381ad68e758aa8e44fa0d6d5a2335aa5fe3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK4 CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.27e-062001217e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

CHDH CCDC168 ADAMTS12 NAV2 RORC FHL1

3.35e-061491216d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCellsevere_influenza-CD4+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

MYC NPM1 ANK3 C12orf56 RPS4X ZAR1

4.70e-061581216ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1C FRMPD4 POLE CIP2A SFMBT2 ST18

5.42e-061621216bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

TROAP TRIM45 LIG1 KIR3DL3 KIR2DL3 KIR3DL1

7.39e-0617112164ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 LRRK2 OBSL1 RNF43 RORC PLCH1

9.59e-061791216fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TROAP POLE LIG1 KIR2DL1 KIR2DL3 KIR3DL1

1.02e-051811216e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 LRRK2 OBSL1 RNF43 RORC PLCH1

1.09e-051831216e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYC NPM1 RPS4X RPS4Y1 TNRC6B RPL18A

1.16e-051851216f60b39010b9210a5f18ccd113758512bd15d7eec
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

CACNA1C ANK3 LAMA4 ADAMTS12 SEMA6D FHL1

1.19e-051861216cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 LRRK2 RNF43 NAV2 RORC PLCH1

1.19e-051861216e83718fabb057100835d3357df407f283d23fe16
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHAF1B POLE CIP2A LIG1 MSH6 PLCH1

1.27e-0518812160ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCellBac-SEP-Lymphocyte-T_NK-CD4_TCM|Bac-SEP / Disease, Lineage and Cell Type

MYC NPM1 ANK3 RPS4X RPS4Y1 RPL18A

1.31e-05189121670f918dc208cd7ce8de9007729d8c5743c56c130
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD4_TCM|Leuk-UTI / Disease, Lineage and Cell Type

MYC NPM1 ANK3 RPS4X RPS4Y1 RPL18A

1.35e-0519012165f8d606d2f465ddeae7451835f84b3f25a151d2a
ToppCell(1)_T_cells-(1)_T_CD8_gd|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SWAP70 RPS4Y1 OPHN1 KIR3DL3 KIR2DL1 KIR3DL1

1.35e-051901216268772d2adff34f7175b8474e95b67fd96dc1234
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 LRRK2 PRAG1 NAV2 PLCH1 PDZD2

1.39e-051911216ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

CACNA1C ANK3 LAMA4 ADAMTS12 SEMA6D FHL1

1.39e-05191121678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.39e-0519112166688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.43e-05192121699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 CACNA1C LAMA4 ADAMTS12 SH3D19 FHL1

1.47e-051931216b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellsevere-CD4+_Tcm|severe / disease stage, cell group and cell class

MYC NPM1 ANK3 RPS4X RPS4Y1 RPL18A

1.51e-051941216380fbd19b72af6767f98bbf50329686b76d59c54
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPM1 CACNA1C LAMA4 ADAMTS12 SH3D19 FHL1

1.51e-0519412168c37bedb23285735ff3828db3889897fada8c95d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TROAP POLE CIP2A LIG1 MSH6 DNMT1

1.51e-0519412164c1d13d8cb6fb424655c67755ee6dbaf59d6b418
ToppCell(1)_T_cells-(1)_T_CD4_conv|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MYC NPM1 RPS4X RPS4Y1 FHL1 RPL18A

1.56e-05195121667ea0d48a31feed886e356a71740981b64f4d658
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.56e-05195121661c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.56e-051951216603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C LAMA4 ADAMTS12 SH3D19 NAV2 FHL1

1.56e-051951216aa0add081881d349099d12efca5cdee098038d4e
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPM1 CACNA1C LAMA4 ADAMTS12 SNCAIP FHL1

1.61e-051961216dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPS4X RPS4Y1 KIR2DL1 KIR2DL3 KIR3DL1 RPL18A

1.61e-05196121664b23d819efddb25024c86f2e1b5dc4159337ddd
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPS4X RPS4Y1 KIR2DL1 KIR2DL3 KIR3DL1 RPL18A

1.61e-051961216ba46f80d1497eaf4d71b59504106ba4b84e4ff9f
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPS4X RPS4Y1 KIR2DL1 KIR2DL3 KIR3DL1 RPL18A

1.61e-051961216eb0b711ca6da7b5e5313791c3c3985358e2a222e
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TNK1 CACNA1C LRRK2 LRTM1 PLEKHG2 SNCAIP

1.65e-0519712164edf043e8f586fd375f56485841fe992a18bf853
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

RPS4Y1 LRRK2 LAMA4 ACAD10 ADAMTS12 FHL1

1.65e-0519712160a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellnormal|World / PBMC cell types (v2) per disease, treatment status, and sex

MYC NPM1 RPS4X TNRC6B SH3D19 RPL18A

1.65e-051971216232e48864aeb5ad6688352383427fb1771986ddc
ToppCell10x5'-blood-Lymphocytic_T_CD4|blood / Manually curated celltypes from each tissue

MYC NPM1 ANK3 RPS4X RPS4Y1 RPL18A

1.70e-051981216a7e39a045e035beaf19f0f0aeb4248d0762da630
ToppCell10x5'-blood-Lymphocytic_T_CD4-Teffector/EM_CD4|blood / Manually curated celltypes from each tissue

MYC NPM1 ANK3 RPS4X RPS4Y1 RPL18A

1.70e-0519812161025036301e0bd7daa75bd8a86e123a70ad7adc7
ToppCellEnterocyte_Progenitors|World / shred on cell type and cluster

MYC NPM1 RPS4X RNF43 PHF14 RPL18A

1.75e-051991216776bcc887927dea9ebd76ec4338ce2225c319c2c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related|6m / Sample Type, Dataset, Time_group, and Cell type.

MYC NPM1 RPS4X RPS4Y1 LRTM1 RPL18A

1.80e-052001216ea1e3eeddbc398ac97863120f7aa3f17569ca12a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related-Oligodendrocyte/OPC|6m / Sample Type, Dataset, Time_group, and Cell type.

MYC NPM1 RPS4X RPS4Y1 LRTM1 RPL18A

1.80e-0520012164a57f2f2dc6e2402ac4772b5cd38e033a6f1adee
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

C8orf88 ANK3 LAMA4 FAM161A ASB2 FHL1

1.80e-052001216c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TROAP POLE CIP2A LIG1 MSH6 DNMT1

1.80e-05200121604bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TROAP POLE CIP2A LIG1 MSH6 DNMT1

1.80e-052001216f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD4+_Tcm|Bac-SEP / Disease, condition lineage and cell class

MYC NPM1 ANK3 RPS4X RPS4Y1 RPL18A

1.80e-052001216fe0e0b25fbe2c7bad6bffef17f62bf346c83fc54
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

DLGAP2 FAM3B CCDC168 LIAT1 FHL1

4.18e-051411215399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK4 LRRK2 MEFV TTBK2 RORC

4.62e-051441215b638398f559e7fd9d4294d1c830beeb20f905960
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BRME1 LIG1 SNCAIP TJP1 POLR1B

4.93e-0514612152d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C ADAMTS12 SH3D19 NAV2 SLC4A9

5.26e-05148121581a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHANK1 FRMPD4 TRPC5 SKOR1 PLCH1

5.44e-0514912156e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHAF1B POLE LIG1 SEMA6D DNMT1

6.96e-0515712152c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCellsevere_influenza-CD4+_T_naive|World / disease group, cell group and cell class (v2)

MYC ANK3 C12orf56 RPS4X ZAR1

7.18e-0515812158ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

ANK3 KAT6A TNRC6B KDM5D NT5C1B

8.08e-051621215b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellICU-SEP-Lymphocyte-T_NK-CD4_Naive|ICU-SEP / Disease, Lineage and Cell Type

MYC NPM1 ANK3 RPS4X RPL18A

8.31e-051631215415e67aaae7ccd97a003b4b31b27eed94737deca
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TROAP LIG1 KIR2DL1 KIR2DL3 KIR3DL1

8.31e-051631215466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM C3orf62 CHDH LENG9 TIGD5

8.56e-051641215b77995958c938e10a526118f75d78cee72e0b207
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM ACAD10 RNF43 PABIR2 NKX2-2

8.56e-0516412150853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCellmild_COVID-19_(asymptomatic)-CD4+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

MYC NPM1 TNK1 ANK3 ZAR1

9.32e-05167121578d264af390bd89942ffbb2991dc94f50756d4c9
ToppCellBAL-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

TROAP TRIM45 LIG1 KIR2DL1 KIR3DL1

9.32e-0516712156c5aa9077ae7eb8887269d405972bd5b31596b19
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM RNF43 MYBPHL ASB2 PCK1

9.59e-0516812150e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

SHANK1 CRACDL RORC FHL1 PDZD2

9.59e-051681215d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1B POLE CIP2A BRME1 LIG1

9.86e-051691215e7514956b2e4298222ec443f98b2f5289451786e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 SEMA6D TESK2 ASB2 PLCH1

1.01e-041701215985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

DOCK4 ANK3 TJP1 NAV2 PDZD2

1.01e-041701215e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

SHANK1 CRACDL RORC FHL1 PDZD2

1.01e-04170121597df5ffb328196c46568975d2d97722bcc753bf5
ToppCellInt-URO-Lymphocyte-T_NK-CD4_Naive|Int-URO / Disease, Lineage and Cell Type

MYC NPM1 ANK3 RPS4X RPL18A

1.01e-041701215577915dd1f5c418b9b98a7a7153e2b5d1b93ca84
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

C12orf56 POLE LAMA4 TRIM45 SH3D19

1.04e-0417112152a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHAF1B POLE LIG1 PLCH1 DNMT1

1.07e-0417212157c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM TRPC5 OBSL1 FAM161A NKX2-2

1.10e-0417312152b448acd5e584f24567204c31b8d74715e92f32a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 CCDC168 SEMA6D ASB2 PLCH1

1.10e-0417312159a2d42f8d9cb834856522661d524abb91c4637c5
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM TROAP CIP2A ASB2 PCK1

1.10e-0417312156c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM TRPC5 OBSL1 FAM161A NKX2-2

1.10e-0417312155086edc29c5a6137ca09877929a1317f9739c801
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-CD4_TEM|Multiple_Sclerosis / Disease, Lineage and Cell Type

NPM1 RPS4X RPS4Y1 FHL1 ST18

1.13e-041741215d2ea5b55bf03a8013816d073896208f311c3e544
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 CCDC168 SEMA6D ASB2 PLCH1

1.13e-041741215b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM SWAP70 RNF43 SFMBT2 MYBPHL

1.16e-04175121591cb819a1786020713b7e64480de0545380daae9
ToppCellsevere_influenza-Plasmablast|World / disease group, cell group and cell class (v2)

DLGAP2 C12orf56 MNX1 TROAP CCDC168

1.16e-041751215e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 CCDC168 PRAG1 ASB2 PLCH1

1.19e-04176121540993c41c1017b53039a337174fc56632b278609
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 TNRC6B ACAD10 SH3D19 FHL1

1.22e-041771215b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHAF1B POLE NT5C1B LIG1 DNMT1

1.22e-0417712158a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TROAP CIP2A ZC3H6 TRIM45 FHL1

1.26e-041781215c87945146b2734141f07b39d268e0d8086ee0364
ToppCellC_00|World / shred on cell type and cluster

RPS4X RNF43 ZNHIT6 PHF14 RPL18A

1.29e-041791215da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCellURO-Lymphocyte-T_NK-CD4_TCM|URO / Disease, Lineage and Cell Type

MYC ANK3 RPS4X RORC RPL18A

1.29e-041791215cdf972acf23c7a22c99a336ee0f9cc51e0fa6f67
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DSCAM SEMA6D TJP1 NAV2 PDZD2

1.29e-0417912154f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4X POLE LIG1 DNMT1 RPL18A

1.36e-0418112159fce5eee75684a7ecac6996e26e9215bc95098b2
ToppCellBL-critical-LOC-Lymphoid-NKT|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPM1 RPS4X RPS4Y1 LRTM1 RPL18A

1.36e-041811215e3add2412c9f8eddfb77e0fbcd66fe57b23ae513
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYC C8orf88 CIP2A FAM3B PLCH1

1.36e-041811215c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4X POLE LIG1 DNMT1 RPL18A

1.36e-041811215ad97e802e934738ddece675232a72308db2da256
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C LAMA4 ADAMTS12 SH3D19 FHL1

1.36e-0418112159ede19228ba5c0668a9c06c915510b95585216ef
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

CACNA1C BRME1 RORC ASB2 FHL1

1.36e-041811215cc7ae1221a28bc404138a7efee0ad08a19cc3d86
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1B LRTM1 PRAG1 SEMA6D CRACDL

1.39e-041821215a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYC NPM1 RPS4Y1 TNRC6B KDM5D

1.39e-0418212153a3ed195c15d33d46a2f395cb93018e4bba28353
ToppCellMild-CD4+_T|World / Disease group and Cell class

MYC TRIM21 PRAG1 RORC ASB2

1.43e-041831215c4ac8893d38a3da4e19fe2ef1756bd69c89e975c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 LRRK2 RNF43 PLCH1 PDZD2

1.43e-0418312156847c1252d6bb105524f812658112517fd351eab
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 ACAD10 NAV2 RORC PLCH1

1.47e-04184121551e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellremission-CD8+_T_naive|remission / disease stage, cell group and cell class

MYC NPM1 RPS4X RPS4Y1 RPL18A

1.47e-041841215fe20fa4457d4a4a75689978275b0afb5f6243faf
Diseaselevel of killer cell immunoglobulin-like receptor 2DS2 in blood serum

KIR3DL3 KIR2DL1 KIR2DL3

5.47e-0831133OBA_2042107
Diseaseovarian neoplasm

MYC MUC16 RNF43 MSH6 MACIR TP53BP1

1.33e-051341136C0919267
Diseaseascending colon cancer (is_implicated_in)

POLE RNF43

1.45e-0521132DOID:218 (is_implicated_in)
DiseaseMalignant neoplasm of ovary

MYC MUC16 RNF43 MSH6 MACIR TP53BP1

1.51e-051371136C1140680
Diseasekiller cell immunoglobulin-like receptor 2DS2 measurement

KIR3DL3 KIR2DL1 KIR2DL3

2.41e-05151133EFO_0801746
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D OPHN1

2.95e-05161133DOID:0050888 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

8.68e-0541132DOID:0060809 (implicated_via_orthology)
DiseaseEndometrial Carcinoma

MYC POLE RNF43 MSH6

1.72e-04721134C0476089
Diseaseautism spectrum disorder (implicated_via_orthology)

SHANK1 DSCAM KDM5C TRPC5 KDM5D

3.05e-041521135DOID:0060041 (implicated_via_orthology)
Diseaseendometrial cancer (is_implicated_in)

POLE RNF43 MSH6

3.56e-04361133DOID:1380 (is_implicated_in)
Diseaseovarian cancer (implicated_via_orthology)

POLE MSH6

4.01e-0481132DOID:2394 (implicated_via_orthology)
Diseaseacquired immunodeficiency syndrome (is_implicated_in)

KIR2DL1 KIR3DS1

5.14e-0491132DOID:635 (is_implicated_in)
Diseasealcohol use disorder measurement, alcohol consumption measurement

CACNA1C TRIM66 SEMA6D PLCH1

5.37e-04971134EFO_0007878, EFO_0009458
Diseasemortality

NT5C1B SFMBT2 ADAMTS12 PHF14 PDZD2

5.51e-041731135EFO_0004352
DiseaseChildhood Medulloblastoma

MYC KAT6A DNMT1

6.04e-04431133C0278510
DiseaseMelanotic medulloblastoma

MYC KAT6A DNMT1

6.04e-04431133C1275668
DiseaseMedullomyoblastoma

MYC KAT6A DNMT1

6.04e-04431133C0205833
DiseaseDesmoplastic Medulloblastoma

MYC KAT6A DNMT1

6.04e-04431133C0751291
DiseaseAdult Medulloblastoma

MYC KAT6A DNMT1

6.04e-04431133C0278876
Diseasetheophylline measurement

LRRK2 NAV2

6.41e-04101132EFO_0021180
DiseaseAnxiety States, Neurotic

SHANK1 CACNA1C DNMT1

6.46e-04441133C0376280
DiseaseAnxiety neurosis (finding)

SHANK1 CACNA1C DNMT1

6.46e-04441133C1279420
DiseaseAnxiety Disorders

SHANK1 CACNA1C DNMT1

6.46e-04441133C0003469
Diseasenucleus accumbens volume change measurement

DSCAM MUC16

7.82e-04111132EFO_0021493
Diseasemismatch repair cancer syndrome (is_implicated_in)

POLE MSH6

9.36e-04121132DOID:0112182 (is_implicated_in)
DiseaseMedulloblastoma

MYC KAT6A DNMT1

9.40e-04501133C0025149
Diseasetriacylglycerol 48:4 measurement

DSCAM SFMBT2

1.28e-03141132EFO_0010407
Diseaseurate measurement, spine bone mineral density

FAM3B CEP89 NAV2

1.45e-03581133EFO_0004531, EFO_0007701
DiseaseEndometrial Neoplasms

MYC RNF43 MSH6

1.45e-03581133C0014170
Diseasetuberculosis

FAM47A FRMPD4 DSCAM LAMA4 C2CD2

1.48e-032161135MONDO_0018076
Diseasecreatinine measurement

CHAF1B DSCAM C3orf62 MAP3K14 TNRC6B ACAD10 INTS8 CEP89 MYBPHL PCK1 SOS2

1.54e-0399511311EFO_0004518
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

RPS4Y2 KDM5D

1.68e-03161132C1839071
DiseaseSpermatogenic failure, Y-linked, 2

RPS4Y2 KDM5D

1.68e-03161132cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

RPS4Y2 KDM5D

1.68e-03161132415000
Diseasechildhood onset asthma

MYC ACO2 ZNF217 PHF14 RORC PDZD2

1.84e-033341136MONDO_0005405
Diseasehypertrophic cardiomyopathy (is_marker_for)

FHL1 DNMT1

1.90e-03171132DOID:11984 (is_marker_for)
Diseaseage at menarche

DLGAP2 CHAF1B DSCAM PHF21A TRIM66 MSH6 SEMA6D ST18

2.07e-035941138EFO_0004703
DiseaseMalignant neoplasm of endometrium

POLE MSH6

2.14e-03181132C0007103
DiseaseCarcinoma in situ of endometrium

POLE MSH6

2.14e-03181132C0346191
Diseaseneurodegenerative disease (implicated_via_orthology)

ACO2 TRPC5 LRRK2 CEP89

2.38e-031451134DOID:1289 (implicated_via_orthology)
DiseaseNonorganic psychosis

SHANK1 CACNA1C ANK3

2.38e-03691133C0349204
DiseaseColonic Neoplasms

MYC MACIR TP53BP1 DNMT1

2.82e-031521134C0009375
Diseasepsychotic symptoms

ANK3 PLCH1 ST18

2.91e-03741133EFO_0005940
DiseaseHIV-1 infection, Susceptibility to viral and mycobacterial infections

BICRA NAV2

2.91e-03211132EFO_0000180, Orphanet_391311
DiseaseParkinson disease

LRRK2 SNCAIP

3.19e-03221132cv:C0030567
DiseaseMalignant tumor of colon

MYC MACIR TP53BP1 DNMT1

3.32e-031591134C0007102
DiseaseAutistic Disorder

SHANK1 DOCK4 CACNA1C DLGAP2 KDM5C

3.37e-032611135C0004352
Diseasemean corpuscular hemoglobin concentration

SWAP70 TNRC6B ZNF217 ACAD10 SKI INTS8 RNF43 MEFV TTBK2 UGT2B10 MACIR

3.46e-03110511311EFO_0004528
Diseaseblood zinc measurement

DLGAP2 TRIM45

3.49e-03231132EFO_0007584
DiseaseGlioblastoma

MYC MACIR TP53BP1

3.50e-03791133C0017636
DiseaseAnhedonia

CACNA1C ANK3

3.80e-03241132C0178417
Diseasemalaria (is_implicated_in)

KIR3DL1 KIR3DS1

3.80e-03241132DOID:12365 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
AGAPKSPILVKIRPH

NT5C1B

566

Q96P26
DFTPGKPLKCIIKHP

ACO2

731

Q99798
ARIPPPKCLPSQHKR

SLC4A9

331

Q96Q91
PPPLAKAIGLEIKLC

DNMT1

1581

P26358
IKEKAEPPRPLAHLC

ASB2

586

Q96Q27
CDKLKSFHLSPRGPP

SH3BP2

331

P78314
RPIAHLPCPGKATLA

CHAF1B

276

Q13112
LRKKPPGTLLPSAHA

ACAD10

311

Q6JQN1
KPLLHQDAKPALRPC

DLGAP2

391

Q9P1A6
LPPTDCQHLLKPKTL

ADAMTS12

921

P58397
LKKLGIPVVCHLPGV

CHDH

316

Q8NE62
PPVVLRLKCGSGPVH

NPM1

96

P06748
LKTRAECLLHPLPPS

NPIPB3

366

Q92617
HLPPPAKSTLILVCG

CYB5R2

236

Q6BCY4
KCLHSVGCPLPLQKP

PCK1

191

P35558
ESLLEKHLRKPCPDP

INTS8

31

Q75QN2
KHLRKPCPDPAPVQL

INTS8

36

Q75QN2
PDCKVLKPLLSGSIP

INTS9

576

Q9NV88
HRKPSLLAHPGPLVK

KIR2DS2

26

P43631
KSPSRPILDGKLEPC

OPHN1

651

O60890
LKTRAECLLHPLPPS

NPIPB12

366

F8W0I5
SICRKKPDFLPDHPI

C8orf88

91

P0DMB2
HTKLCLEKPLGPSVL

EXO5

241

Q9H790
TLLRVKCVKHSPPGP

OBSL1

506

O75147
KCVKHSPPGPPILAE

OBSL1

511

O75147
LCLEPPKTRGSHLRP

FAM47C

426

Q5HY64
DAICTHRPDPKIPGL

MUC16

13236

Q8WXI7
CELKPKPRPANLRHA

LRTM1

271

Q9HBL6
HRKPSLLAHPGPLVK

KIR2DL3

26

P43628
PRLLAAHCALLPKPG

MNX1

81

P50219
PIAEKSGICKIRPPA

KDM5D

36

Q9BY66
PDPHKGLVLLPKTEC

CORO7

776

P57737
HRKPSLLAHPGPLVK

KIR3DL1

121

P43629
RKLVLLGPHVLCAPP

LENG9

401

Q96B70
GPLPLCLLKGKRAHS

MACIR

151

Q96GV9
LSKVHAILSKCPPGP

PDZD2

791

O15018
HRKPSLLAHPGPLVK

KIR3DL3

121

Q8N743
CHLKPSLLLRPRGKD

NOL6

231

Q9H6R4
HLDCLDPPLKTIPKG

PHF21A

511

Q96BD5
EGCPKHPKGIISRRD

LRRK2

1616

Q5S007
LKTRAECLLHPLPPS

NPIPB5

366

A8MRT5
SLSPQPLPQCKRHLK

MEFV

366

O15553
GLVKLPHPAAPVTVK

POLE

1216

Q07864
PPFLELKGSRHPCIT

MSH6

1086

P52701
LKTRAECLLHPLPPS

NPIPB4

366

C9JG80
PVLKAPVPKRQKCDH

FAM3B

51

P58499
HLGCLDPPLTRMPRK

PHF14

751

O94880
PPAPKSCLKHRPAAA

CRACDL

491

Q6NV74
RRKPSLLAHPGPLVK

KIR2DS5

26

Q14953
SPVKCIRPSVLGPLK

PABIR2

151

Q7Z309
QVKRPLPHPKDVKCF

PASD1

441

Q8IV76
SCLPPVSLLPHEKDK

KAT6A

186

Q92794
KPPVCHGKRLPLTLF

FHL1

246

Q13642
KLRTSGEGLCPPKPL

BRME1

6

Q0VDD7
ESCPPKPPRAHELKL

C2CD2

251

Q9Y426
GPRPRPLSELHLKEK

CACNA1C

856

Q13936
KPREPLCPLKHPSHQ

C5orf60

196

A6NFR6
LPKAPDKPERHCSLF

DOCK4

246

Q8N1I0
KHPVLNLKDEKPPLC

CEP89

201

Q96ST8
ESPLCPSLGKHLIPD

FRMPD4

1236

Q14CM0
NAKPHALCPERKPLT

C3orf62

101

Q6ZUJ4
EEPPINHPVGCKRKL

ZNHIT6

201

Q9NWK9
TCRLVKRHKLANPPP

ANK3

1021

Q12955
THLGICSLEIRKPGP

MYBPHL

311

A2RUH7
VPRAKIHSLPPEGKL

COX8A

21

P10176
PVPPKTGVCHLRLEP

FAM47A

401

Q5JRC9
GKHGPRPCCPLLRKF

LINC02913

196

Q8NAJ2
PPCSEGIHLNIKGRK

CCDC168

3241

Q8NDH2
LKDAKAPPGCLTPER

DGLUCY

256

Q7Z3D6
KHKVRCPTPDFEDLP

FAM161A

421

Q3B820
LGTAPHCPRLPLRKT

BICRA

1376

Q9NZM4
ERLPEHCKLSPGIPL

LIG1

526

P18858
HCKLSPGIPLKPMLA

LIG1

531

P18858
HRKPSLLAHPGPLVK

KIR2DL1

26

P43626
LKTRAECLLHPLPPS

NPIPB13

366

A6NJU9
PRLAPSKPFTGCIRH

LAMA4

1781

Q16363
LSKLACVDSPKPLPG

MAP3K14

301

Q99558
VAHLPLEKLGPCLPL

PHF20L1

461

A8MW92
RVELPCKALGHPEPD

DSCAM

241

O60469
RLCKSFLGEHKPPKL

SKOR1

161

P84550
GKPILCPVHPAEELR

TRIM45

186

Q9H8W5
TLRGHPTPLEREPCK

SOS2

1051

Q07890
PTVIRIPAKPGKCLH

SH3D19

256

Q5HYK7
PPPDHKGRLSILKVC

SPATA5L1

651

Q9BVQ7
LHSIKCKPPLSSPIL

LCMT1

131

Q9UIC8
ILSPCKERGPKPEHR

LIAT1

121

Q6ZQX7
GHSKPPHSPLVLKRC

MYC

286

P01106
HRKPSLLAHPGPLVK

KIR3DS1

121

Q14943
KSGLPKPVHSAAPIL

NAV2

11

Q8IVL1
AHPLICGPPGLDKRL

RNF43

696

Q68DV7
PFCVLSPVKSPHLRK

SNCAIP

206

Q9Y6H5
PSTGPHKLRECLPLI

RPS4Y1

31

P22090
PSTGPHKLRECLPLI

RPS4Y2

31

Q8TD47
PVLVRDGKPCHALKA

NKX2-2

206

O95096
PSTGPHKLRECLPLI

RPS4X

31

P62701
KVVGRCLPTPKCHTP

RPL18A

11

Q02543
PPPCKKELAASLALG

SKI

196

P12755
RPLVHPLTGKALDPA

SHANK1

1336

Q9Y566
KHSPRPEKRETKCPI

ST18

356

O60284
GEASIPSPKPKLHAR

ST18

701

O60284
IKCLTPHLKDGVPGL

CIP2A

581

Q8TCG1
TLCPRPGLKKLSLHG

C12orf56

176

Q8IXR9
KLPPLCHGLPTQRED

TMX2

41

Q9Y320
TCRLLVSLGHPVPKP

ZNF599

41

Q96NL3
RPGTNPHKEICPEKL

ZNF599

136

Q96NL3
PTVDLAHKIGRKPPA

ZC3H6

436

P61129
LPPKGKLRSLCSQHV

RORC

466

P51449
GKESILPALLHKPCV

TTBK2

481

Q6IQ55
VPVKKIPHDLCLFPH

SFMBT2

501

Q5VUG0
LPGLLKHSGLPKPCL

TROAP

491

Q12815
ATPPLIGHLKLEPKR

TP53BP1

921

Q12888
APVRCPPAKGASLLH

PYCARD-AS1

121

I3L0S3
PTAHPSCLGPKKLSL

PRAG1

316

Q86YV5
SPELRSVCHVPGLKK

TRIM21

266

P19474
HCPLPSLGLKMPIKH

PLCH1

1226

Q4KWH8
KFLKPVELRLPHCDP

TJP1

1706

Q07157
SPRHLPEPEGGLKCL

TNK1

96

Q13470
VGGLHCKPAKPLPKE

UGT2B10

276

P36537
HPETGKKPVRCIPQL

ZNF217

276

O75362
HLLKLGSPPPHKEAR

SWAP70

306

Q9UH65
LHCAPKSKPVLEPLT

PLEKHG2

431

Q9H7P9
LGCKKKTCHGPPLIR

TRPC5

801

Q9UL62
SHKLKPLVIGRLPDP

TIGD5

286

Q53EQ6
VKCGSLLSPLLEKPP

POLR1B

1071

Q9H9Y6
SLDDKIPHKSPCPRR

TESK2

346

Q96S53
KVPKPRPGCCAKHGL

SEMA6D

361

Q8NFY4
KELACSPHPPKLLQP

TRIM66

371

O15016
HKVLLKRGQPPPPSC

TNRC6B

101

Q9UPQ9
LSPPSIHCLGPIKLE

VPS39

746

Q96JC1
CPVKLRHVDPKRPHR

ZAR1

386

Q86SH2
PIAEKSGICKIRPPA

KDM5C

36

P41229