Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin ligase complex scaffold activity	CUL4A CUL2 CUL1	5.07e-06	6	128	3	GO:0160072
MousePheno	decreased circulating unsaturated transferrin level	LRP1B LDLR SLC40A1	1.61e-05	8	94	3	MP:0011897
MousePheno	decreased circulating transferrin level	LRP1B LDLR SLC40A1	3.41e-05	10	94	3	MP:0011894
Domain	Cullin_CS	CUL4A CUL2 CUL1	1.08e-05	7	128	3	IPR016157
Domain	CULLIN	CUL4A CUL2 CUL1	1.08e-05	7	128	3	SM00182
Domain	Cullin_neddylation_domain	CUL4A CUL2 CUL1	1.72e-05	8	128	3	IPR019559
Domain	Cullin_Nedd8	CUL4A CUL2 CUL1	1.72e-05	8	128	3	PF10557
Domain	Cullin_Nedd8	CUL4A CUL2 CUL1	1.72e-05	8	128	3	SM00884
Domain	Cullin_homology	CUL4A CUL2 CUL1	2.56e-05	9	128	3	IPR016158
Domain	Cullin	CUL4A CUL2 CUL1	3.64e-05	10	128	3	PF00888
Domain	CULLIN_2	CUL4A CUL2 CUL1	3.64e-05	10	128	3	PS50069
Domain	Cullin_N	CUL4A CUL2 CUL1	3.64e-05	10	128	3	IPR001373
Domain	CULLIN_1	CUL4A CUL2 CUL1	3.64e-05	10	128	3	PS01256
Domain	Ceramidse_alk_C	ASAH2 ASAH2B	4.66e-05	2	128	2	PF17048
Domain	NEUT/ALK_ceramidase_C	ASAH2 ASAH2B	4.66e-05	2	128	2	IPR031331
Domain	Ceramidase_alk	ASAH2 ASAH2B	4.66e-05	2	128	2	IPR006823
Domain	Frizzled	FZD7 SMO FZD2	4.98e-05	11	128	3	IPR000539
Domain	Frizzled	FZD7 SMO FZD2	4.98e-05	11	128	3	PF01534
Domain	Frizzled	FZD7 SMO FZD2	4.98e-05	11	128	3	SM01330
Domain	Cullin_repeat-like_dom	CUL4A CUL2 CUL1	6.61e-05	12	128	3	IPR016159
Domain	Frizzled/SFRP	FZD7 SMO FZD2	1.65e-04	16	128	3	IPR015526
Domain	WD40_repeat_dom	CFAP251 LRWD1 UBR4 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	2.10e-04	297	128	9	IPR017986
Domain	C_TYPE_LECTIN_1	MRC1 FREM1 KLRF1 ATRNL1 CD302	2.23e-04	80	128	5	PS00615
Domain	Lectin_C	MRC1 FREM1 KLRF1 ATRNL1 CD302	2.80e-04	84	128	5	PF00059
Domain	CLECT	MRC1 FREM1 KLRF1 ATRNL1 CD302	2.80e-04	84	128	5	SM00034
Domain	C_TYPE_LECTIN_2	MRC1 FREM1 KLRF1 ATRNL1 CD302	2.96e-04	85	128	5	PS50041
Domain	C-type_lectin-like	MRC1 FREM1 KLRF1 ATRNL1 CD302	3.12e-04	86	128	5	IPR001304
Domain	FRI	FZD7 SMO FZD2	3.29e-04	20	128	3	SM00063
Domain	-	FZD7 SMO FZD2	3.82e-04	21	128	3	1.10.2000.10
Domain	WD40	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	4.19e-04	259	128	8	PF00400
Domain	K_chnl_volt-dep_KCNQ_C	KCNQ5 KCNQ3	4.60e-04	5	128	2	IPR013821
Domain	K_chnl_volt-dep_KCNQ	KCNQ5 KCNQ3	4.60e-04	5	128	2	IPR003937
Domain	KCNQ_channel	KCNQ5 KCNQ3	4.60e-04	5	128	2	PF03520
Domain	WD40	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	5.25e-04	268	128	8	SM00320
Domain	-	MRC1 FREM1 KLRF1 ATRNL1 CD302	5.44e-04	97	128	5	3.10.100.10
Domain	Frizzled_dom	FZD7 SMO FZD2	5.73e-04	24	128	3	IPR020067
Domain	FZ	FZD7 SMO FZD2	5.73e-04	24	128	3	PS50038
Domain	Fz	FZD7 SMO FZD2	5.73e-04	24	128	3	PF01392
Domain	WD40_repeat	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	5.79e-04	272	128	8	IPR001680
Domain	C-type_lectin-like/link	MRC1 FREM1 KLRF1 ATRNL1 CD302	5.98e-04	99	128	5	IPR016186
Domain	WD_REPEATS_1	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	6.68e-04	278	128	8	PS00678
Domain	WD_REPEATS_2	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	6.84e-04	279	128	8	PS50082
Domain	WD_REPEATS_REGION	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	6.84e-04	279	128	8	PS50294
Domain	HELP	EML6 EML1	6.87e-04	6	128	2	PF03451
Domain	HELP	EML6 EML1	6.87e-04	6	128	2	IPR005108
Domain	CTDL_fold	MRC1 FREM1 KLRF1 ATRNL1 CD302	8.50e-04	107	128	5	IPR016187
Domain	EGF_1	LAMB4 EDIL3 LRP1B LDLR MFGE8 HEG1 ATRNL1	1.90e-03	255	128	7	PS00022
Domain	-	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	2.11e-03	333	128	8	2.130.10.10
Domain	EGF-like_CS	LAMB4 EDIL3 LRP1B LDLR MFGE8 HEG1 ATRNL1	2.16e-03	261	128	7	IPR013032
Domain	WD40/YVTN_repeat-like_dom	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	2.19e-03	335	128	8	IPR015943
Domain	ARM-type_fold	SAAL1 ATR UBR4 RALGAPA2 PSME4 PIK3C2B PKP2 IPO13	2.35e-03	339	128	8	IPR016024
Domain	EGF_2	LAMB4 EDIL3 LRP1B LDLR MFGE8 HEG1 ATRNL1	2.36e-03	265	128	7	PS01186
Domain	ABC_A	ABCA7 ABCA8	2.94e-03	12	128	2	IPR026082
Domain	Peptidase_M28	ERMP1 TFRC	2.94e-03	12	128	2	PF04389
Domain	Peptidase_M28	ERMP1 TFRC	2.94e-03	12	128	2	IPR007484
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH7	4.02e-03	14	128	2	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH7	4.02e-03	14	128	2	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH7	4.02e-03	14	128	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH7	4.02e-03	14	128	2	PF08393
Domain	MT	DYNC2H1 DNAH7	4.02e-03	14	128	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH7	4.02e-03	14	128	2	PF12780
Domain	Ldl_recept_b	LRP1B LDLR	4.02e-03	14	128	2	PF00058
Domain	LDLRB	LRP1B LDLR	4.02e-03	14	128	2	PS51120
Domain	EGF_Ca-bd_CS	EDIL3 LRP1B LDLR HEG1	4.46e-03	97	128	4	IPR018097
Domain	DHC_fam	DYNC2H1 DNAH7	4.62e-03	15	128	2	IPR026983
Domain	Dynein_heavy	DYNC2H1 DNAH7	4.62e-03	15	128	2	PF03028
Domain	PI3/4_kinase_CS	ATR PIK3C2B	4.62e-03	15	128	2	IPR018936
Domain	LY	LRP1B LDLR	4.62e-03	15	128	2	SM00135
Domain	Dynein_heavy_dom	DYNC2H1 DNAH7	4.62e-03	15	128	2	IPR004273
Domain	LDLR_classB_rpt	LRP1B LDLR	4.62e-03	15	128	2	IPR000033
Domain	EGF_CA	EDIL3 LRP1B LDLR HEG1	4.80e-03	99	128	4	PS01187
Domain	ASX_HYDROXYL	EDIL3 LRP1B LDLR HEG1	4.97e-03	100	128	4	PS00010
Domain	-	ATR PIK3C2B	5.25e-03	16	128	2	1.10.1070.11
Domain	PI3Kc	ATR PIK3C2B	5.25e-03	16	128	2	SM00146
Domain	Globin-like	ATR CYGB	5.25e-03	16	128	2	IPR009050
Domain	EGF	EDIL3 LRP1B LDLR MFGE8 HEG1 ATRNL1	5.65e-03	235	128	6	SM00181
Domain	EGF_3	EDIL3 LRP1B LDLR MFGE8 HEG1 ATRNL1	5.65e-03	235	128	6	PS50026
Domain	Quinoprotein_ADH-like_supfam	CFAP251 EML6 EML1	5.74e-03	53	128	3	IPR011047
Domain	TF_T-box	TBX20 TBX1	5.93e-03	17	128	2	IPR001699
Domain	TBOX	TBX20 TBX1	5.93e-03	17	128	2	SM00425
Domain	TF_T-box_CS	TBX20 TBX1	5.93e-03	17	128	2	IPR018186
Domain	-	TBX20 TBX1	5.93e-03	17	128	2	2.60.40.820
Domain	TBOX_3	TBX20 TBX1	5.93e-03	17	128	2	PS50252
Domain	T-box	TBX20 TBX1	5.93e-03	17	128	2	PF00907
Domain	TBOX_1	TBX20 TBX1	5.93e-03	17	128	2	PS01283
Domain	TBOX_2	TBX20 TBX1	5.93e-03	17	128	2	PS01264
Domain	EGF-type_Asp/Asn_hydroxyl_site	EDIL3 LRP1B LDLR HEG1	6.10e-03	106	128	4	IPR000152
Domain	PI3_PI4_kinase	ATR PIK3C2B	6.64e-03	18	128	2	PF00454
Domain	PI3_4_KINASE_1	ATR PIK3C2B	6.64e-03	18	128	2	PS00915
Domain	PI3_4_KINASE_2	ATR PIK3C2B	6.64e-03	18	128	2	PS00916
Domain	PI3/4_kinase_cat_dom	ATR PIK3C2B	6.64e-03	18	128	2	IPR000403
Domain	PI3_4_KINASE_3	ATR PIK3C2B	6.64e-03	18	128	2	PS50290
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GPR89B ATR ERAP1 MARCHF6 APEX1 OGFOD3 ERMP1 CPT1A EDIL3 LRP1B MBOAT2 ABCA7 LDLR TFRC HEG1 TMEM259 IPO13 UGGT2 SELENOI TMEM231 QSOX2 DSE ALG1 SLC27A3	2.16e-11	1201	131	24	35696571
Pubmed	The molecular circuitry regulating the switch between iron deficiency and overload in mice.	ASAH2 SLC40A1 ASAH2B	5.22e-08	3	131	3	16418170
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZXDC LRWD1 UBR4 RALGAPA2 NPHP4 DENND1A ABCA7 LDLR ADCY9 ACOX3 FZD7 HEG1 LLGL2 PSME4 PIK3C2B TMEM259 DISP2	9.45e-07	1105	131	17	35748872
Pubmed	cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.	CUL4A CUL2 CUL1	1.04e-06	6	131	3	8681378
Pubmed	Differential dynamics of cullin deneddylation via COP9 signalosome subunit 5 interaction.	CUL4A CUL2 CUL1	1.04e-06	6	131	3	36423380
Pubmed	Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins.	CUL4A CUL2 CUL1	1.81e-06	7	131	3	11861641
Pubmed	Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome.	CUL4A CUL2 CUL1	1.81e-06	7	131	3	32047038
Pubmed	CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.	CUL4A CUL2 CUL1	1.81e-06	7	131	3	24082123
Pubmed	De novo DNA methyltransferase DNMT3b interacts with NEDD8-modified proteins.	CUL4A CUL2 CUL1	1.81e-06	7	131	3	20847044
Pubmed	Covalent modification of all members of human cullin family proteins by NEDD8.	CUL4A CUL2 CUL1	2.88e-06	8	131	3	10597293
Pubmed	Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130).	CUL4A CUL2 CUL1	2.88e-06	8	131	3	23951410
Pubmed	CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.	CUL4A CUL2 CUL1	2.88e-06	8	131	3	12504026
Pubmed	Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.	CUL4A CUL2 CUL1	4.31e-06	9	131	3	15448697
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	CUL2 CUL1 UBR4 MARCHF6 PSME4	5.22e-06	66	131	5	24811749
Pubmed	Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function.	CUL4A CUL2 CUL1	6.15e-06	10	131	3	26976604
Pubmed	Regulation of cullin RING E3 ubiquitin ligases by CAND1 in vivo.	CUL4A CUL2 CUL1	6.15e-06	10	131	3	21249194
Pubmed	The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain.	CUL4A CUL2 CUL1	6.15e-06	10	131	3	22956996
Pubmed	TIP120A associates with cullins and modulates ubiquitin ligase activity.	CUL4A CUL2 CUL1	8.43e-06	11	131	3	12609982
Pubmed	Suramin inhibits cullin-RING E3 ubiquitin ligases.	CUL4A CUL2 CUL1	8.43e-06	11	131	3	27001857
Pubmed	SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.	CUL4A CUL2 CUL1	1.12e-05	12	131	3	18826954
Pubmed	NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway.	CUL4A CUL2 CUL1	1.12e-05	12	131	3	22466964
Pubmed	The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes.	CUL4A CUL2 CUL1	1.12e-05	12	131	3	19617556
Pubmed	KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.	CUL4A CUL2 CUL1	1.12e-05	12	131	3	33173725
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	APEX1 ZNF230 RMDN2 ABCA7 LDLR TFRC FZD7 BRCA2 AKR1C3	1.30e-05	374	131	9	19625176
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	GPR137 UBR4 MARCHF6 CH25H DHRS1 MBOAT2 ABCA7 FZD7 TMEM259 IPO13 SMO TMEM231	1.38e-05	697	131	12	28298427
Pubmed	Genomic structure and promoter analysis of the mouse neutral ceramidase gene.	ASAH2 ASAH2B	1.41e-05	2	131	2	12435403
Pubmed	Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney.	ASAH2 ASAH2B	1.41e-05	2	131	2	11328816
Pubmed	Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells.	KCNQ5 KCNQ3	1.41e-05	2	131	2	11159685
Pubmed	Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation.	ASAH2 ASAH2B	1.41e-05	2	131	2	19345744
Pubmed	Lactosylceramide contributes to mitochondrial dysfunction in diabetes.	ASAH2 ASAH2B	1.41e-05	2	131	2	26900161
Pubmed	A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer's disease.	ASAH2 ASAH2B	1.41e-05	2	131	2	17334805
Pubmed	Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.	ASAH2 ASAH2B	1.41e-05	2	131	2	26747710
Pubmed	GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.	GPR89B GPR89A	1.41e-05	2	131	2	22572823
Pubmed	Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases.	ASAH2 ASAH2B	1.41e-05	2	131	2	10753931
Pubmed	High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation.	ATR TOPBP1	1.41e-05	2	131	2	25916852
Pubmed	Adenovirus 12 E4orf6 inhibits ATR activation by promoting TOPBP1 degradation.	ATR TOPBP1	1.41e-05	2	131	2	20566845
Pubmed	Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids.	ASAH2 ASAH2B	1.41e-05	2	131	2	16380386
Pubmed	Lactadherin deficiency leads to apoptotic cell accumulation and accelerated atherosclerosis in mice.	LDLR MFGE8	1.41e-05	2	131	2	17420351
Pubmed	GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.	GPR89B GPR89A	1.41e-05	2	131	2	18794847
Pubmed	Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.	ASAH2 ASAH2B	1.41e-05	2	131	2	10652340
Pubmed	Neutral ceramidase gene: role in regulating ceramide-induced apoptosis.	ASAH2 ASAH2B	1.41e-05	2	131	2	14557071
Pubmed	TopBP1 assembles nuclear condensates to switch on ATR signaling.	ATR TOPBP1	1.41e-05	2	131	2	33503405
Pubmed	TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint.	ATR TOPBP1	1.41e-05	2	131	2	14718568
Pubmed	Expression of developmental endothelial locus-1 in a subset of macrophages for engulfment of apoptotic cells.	EDIL3 MFGE8	1.41e-05	2	131	2	15004195
Pubmed	Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection.	ASAH2 ASAH2B	1.41e-05	2	131	2	35354041
Pubmed	Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu.	ASAH2 ASAH2B	1.41e-05	2	131	2	16126722
Pubmed	Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease.	ASAH2 ASAH2B	1.41e-05	2	131	2	22940715
Pubmed	Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.	ASAH2 ASAH2B	1.41e-05	2	131	2	24659784
Pubmed	Direct neurotransmitter activation of voltage-gated potassium channels.	KCNQ5 KCNQ3	1.41e-05	2	131	2	29748663
Pubmed	Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.	ASAH2 ASAH2B	1.41e-05	2	131	2	21613224
Pubmed	Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury.	ASAH2 ASAH2B	1.41e-05	2	131	2	35151662
Pubmed	Identification of genetic drivers of plasma lipoprotein size in the Diversity Outbred mouse population.	ASAH2 ASAH2B	1.41e-05	2	131	2	37944753
Pubmed	Role of neutral ceramidase in colon cancer.	ASAH2 ASAH2B	1.41e-05	2	131	2	27609772
Pubmed	Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.	CUL4A CUL2 CUL1	1.45e-05	13	131	3	19037258
Pubmed	The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation.	CUL4A CUL2 CUL1	1.45e-05	13	131	3	29958295
Pubmed	Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.	CUL4A CUL2 CUL1	1.45e-05	13	131	3	23201271
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	APEX1 ZNF230 RMDN2 ABCA7 LDLR TFRC FZD7 BRCA2 AKR1C3	1.51e-05	381	131	9	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	APEX1 ZNF230 RMDN2 ABCA7 LDLR TFRC FZD7 BRCA2 AKR1C3	1.54e-05	382	131	9	19170196
Pubmed	Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1.	CUL4A CUL2 CUL1	1.84e-05	14	131	3	22474075
Pubmed	TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.	CUL4A CUL2 CUL1	1.84e-05	14	131	3	24076655
Pubmed	ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.	CUL4A CUL2 CUL1	1.84e-05	14	131	3	10230407
Pubmed	Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice.	CPT1A LDLR SCD	1.84e-05	14	131	3	22055502
Pubmed	Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome.	CUL4A CUL2 CUL1	1.84e-05	14	131	3	18173839
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CUL4A RALGAPA2 ABCA7 LDLR SLC40A1 ABCA8 ADCY9 TUBGCP6 PTPN14 CIAO1 TCF25 PKP2 BRD1 TSSK4 QSOX2	2.13e-05	1116	131	15	31753913
Pubmed	Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.	ATR TOPBP1 BRCA2	2.82e-05	16	131	3	27760317
Pubmed	CAND1 enhances deneddylation of CUL1 by COP9 signalosome.	CUL4A CUL2 CUL1	2.82e-05	16	131	3	16036220
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	APEX1 ZNF230 RMDN2 ABCA7 LDLR TFRC FZD7 BRCA2 AKR1C3	3.30e-05	421	131	9	19692168
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	TBRG4 ERAP1 USP46 SEC31A NT5DC3 DHRS1 TFRC HEG1 PTPN14 DPP9 SCD TLR3 UGGT2 TMEM231 QSOX2 ALG1 SLC27A3	3.34e-05	1451	131	17	30550785
Pubmed	Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.	CUL4A CUL2 CUL1	4.09e-05	18	131	3	26906416
Pubmed	Adaptive exchange sustains cullin-RING ubiquitin ligase networks and proper licensing of DNA replication.	CUL2 CUL1	4.21e-05	3	131	2	36037385
Pubmed	Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice.	LDLR SCD	4.21e-05	3	131	2	17960025
Pubmed	Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1.	MRC1 ATR	4.21e-05	3	131	2	11715017
Pubmed	Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7.	FZD7 FZD2	4.21e-05	3	131	2	9813155
Pubmed	UV-induced activation of ATR is mediated by UHRF2.	ATR UHRF2	4.21e-05	3	131	2	33848395
Pubmed	Plasma PCSK9 preferentially reduces liver LDL receptors in mice.	LDLR TFRC	4.21e-05	3	131	2	18354138
Pubmed	Unaltered prion disease in mice lacking developmental endothelial locus-1.	EDIL3 MFGE8	4.21e-05	3	131	2	30743056
Pubmed	Identification of a functional hepatocyte nuclear factor 4 binding site in the neutral ceramidase promoter.	ASAH2 ASAH2B	4.21e-05	3	131	2	20803549
Pubmed	Change in iron transporter expression in human term placenta with different maternal iron status.	SLC40A1 TFRC	4.21e-05	3	131	2	18586377
Pubmed	Neutral ceramidase secreted by endothelial cells is released in part associated with caveolin-1.	ASAH2 ASAH2B	4.21e-05	3	131	2	12921776
Pubmed	Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice.	LDLR SCD	4.21e-05	3	131	2	30139760
Pubmed	Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation.	CUL2 CUL1	4.21e-05	3	131	2	28715492
Pubmed	Expression of Hepcidin and Ferroportin in the Placenta, and Ferritin and Transferrin Receptor 1 Levels in Maternal and Umbilical Cord Blood in Pregnant Women with and without Gestational Diabetes.	SLC40A1 TFRC	4.21e-05	3	131	2	27483296
Pubmed	Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis.	LDLR SCD	4.21e-05	3	131	2	19095997
Pubmed	Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways.	ATR BRCA2	4.21e-05	3	131	2	24672057
Pubmed	An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.	ATR TOPBP1	4.21e-05	3	131	2	23950734
Pubmed	Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages.	ASAH2 ASAH2B	4.21e-05	3	131	2	38302493
Pubmed	Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts.	SLC40A1 TFRC	4.21e-05	3	131	2	21700773
Pubmed	RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.	ATR TOPBP1	4.21e-05	3	131	2	32494026
Pubmed	Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation.	KCNQ5 KCNQ3	4.21e-05	3	131	2	12890507
Pubmed	Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.	FZD7 FZD2	4.21e-05	3	131	2	27680706
Pubmed	Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis.	KCNQ5 KCNQ3	4.21e-05	3	131	2	18786918
Pubmed	Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response.	ATR TOPBP1	4.21e-05	3	131	2	31533931
Pubmed	Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells.	ATR TOPBP1	4.21e-05	3	131	2	23226797
Pubmed	ATR activation is regulated by dimerization of ATR activating proteins.	ATR TOPBP1	4.21e-05	3	131	2	33636182
Pubmed	TopBP1 activates ATR through ATRIP and a PIKK regulatory domain.	ATR TOPBP1	4.21e-05	3	131	2	18519640
Pubmed	Expression of intestinal and lung alkaline sphingomyelinase and neutral ceramidase in cystic fibrosis f508del transgenic mice.	ASAH2 ASAH2B	4.21e-05	3	131	2	18955860
Pubmed	Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites.	LDLR SCD	4.21e-05	3	131	2	38354249
Pubmed	Tannic acid activates the Kv7.4 and Kv7.3/7.5 K(+) channels expressed in HEK293 cells and reduces tension in the rat mesenteric arteries.	KCNQ5 KCNQ3	4.21e-05	3	131	2	26969140
Pubmed	STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication.	ATR TOPBP1	4.21e-05	3	131	2	26695634
Pubmed	Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.	GPR89B GPR89A	4.21e-05	3	131	2	32220963
Interaction	GPR21 interactions	MARCHF6 ERMP1 ADCY9 TMEM259 GPR89A FZD2	1.28e-05	81	128	6	int:GPR21
Interaction	OR1D4 interactions	ERMP1 FZD7 FZD2 SLC27A3	2.08e-05	26	128	4	int:OR1D4
Interaction	TTYH1 interactions	ERMP1 CPT1A ABCA7 ADCY9 FZD7 SCD GPR89A SMO FZD2 SLC27A3	2.22e-05	300	128	10	int:TTYH1
Interaction	IGHV3OR15-7 interactions	CUL4A CUL2 CUL1	2.91e-05	10	128	3	int:IGHV3OR15-7
GeneFamily	Cullins	CUL4A CUL2 CUL1	6.13e-06	8	88	3	1032
GeneFamily	G protein-coupled receptors, Class F frizzled	FZD7 SMO FZD2	1.79e-05	11	88	3	286
GeneFamily	WD repeat domain containing	CFAP251 LRWD1 EML6 SEC31A DCAF12L2 LLGL2 CIAO1 EML1	4.13e-05	262	88	8	362
GeneFamily	C-type lectin domain family	MRC1 KLRF1 CD302	1.55e-03	47	88	3	494
GeneFamily	Low density lipoprotein receptors	LRP1B LDLR	1.76e-03	13	88	2	634
GeneFamily	ATP binding cassette subfamily A	ABCA7 ABCA8	2.05e-03	14	88	2	805
GeneFamily	T-boxes	TBX20 TBX1	3.41e-03	18	88	2	766
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NPY2R CYGB STEAP2 PIP5KL1 TCF25 CYP4X1 DISP2	8.66e-07	173	132	7	7e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	MRC1 TCIRG1 CPT1A TFRC LLGL2 DPP9 KCNQ3	1.56e-06	189	132	7	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GPR89B IL12RB1 DENND1A KLRF1 AKR1C3 SLC27A3	1.10e-05	168	132	6	94cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB4 DYNC2H1 CYGB EDIL3 ABCA8 PAPPA	1.14e-05	169	132	6	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	GPR89B DENND1A TFRC TMEM168 SCD SELENOI	1.48e-05	177	132	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	IIH-CD8-antiviral_CD4\|IIH / Condition, Cell_class and T cell subcluster	GPR137 ACOX3 TUBGCP6 SESN2 TMEM231 ALG1	1.48e-05	177	132	6	fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ESPN CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	1.63e-05	180	132	6	92fb01b91261b3103454924cde56add337b41844
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ASAH2 FZD7 LLGL2 AKR1C3 PKP2 SLC27A3	1.79e-05	183	132	6	9a2cd63af5f492d46ce80ca1536312e8ac0e7df4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT EML6 ERMP1 EDIL3 DNAH7 PTPN14	1.84e-05	184	132	6	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 DYNC2H1 RGS22 ARHGAP39 DNAH7 TMEM231	1.90e-05	185	132	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGS22 CYGB ABCA8 MFGE8 CYP4X1 CD302	1.90e-05	185	132	6	e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGS22 CYGB ABCA8 MFGE8 CYP4X1 CD302	1.90e-05	185	132	6	9d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT EML6 ERMP1 EDIL3 DNAH7 PTPN14	2.14e-05	189	132	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT EML6 ERMP1 EDIL3 DNAH7 PTPN14	2.27e-05	191	132	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FREM1 OTC SCD AKR1C3 KCNQ3 CD302	2.48e-05	194	132	6	2f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 APEX1 LRP1B CD302 FZD2 DSE	2.48e-05	194	132	6	6af2971d83f5ad6aed16d0ceb8bfc52f3947bc10
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 APEX1 LRP1B CD302 FZD2 DSE	2.48e-05	194	132	6	5c60670ec24470225fabaa6071fdb4ef6e579840
ToppCell	Monocytes-M2-like_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MRC1 CH25H SLC40A1 CD302 SIGLEC11 DSE	2.55e-05	195	132	6	10fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 DYNC2H1 RGS22 ARHGAP39 DNAH7 TMEM231	2.70e-05	197	132	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	(2)_5-FU-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	ERMP1 SLC40A1 SCD CD302 SMO DSE	2.70e-05	197	132	6	434ae0231972acba12d06279908cf407e70511ac
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DYNC2H1 SLC40A1 ABCA8 FREM1 CD302 SMO	2.86e-05	199	132	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 TFRC BRCA2 SCD AKR1C3 CD302	2.86e-05	199	132	6	e1190b1c2d21fed313bb58e24d0e6365de6e6599
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CH25H CYGB EDIL3 ABCA8 PAPPA CD302	2.86e-05	199	132	6	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	CH25H CYGB ABCA8 PAPPA CD302	4.14e-05	129	132	5	13cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-6\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CFAP251 ABCA8 ATRNL1 IPO13 DISP2	4.62e-05	132	132	5	b7611c6a5c86908132e7ab3e41d67277e8142db1
ToppCell	ASK454-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	UBR4 KLRF1 GPR89A MPND ZNF548	6.99e-05	144	132	5	8e693b50bd6c69ce68f44ca6e51f6d0c7f80d82c
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DENND1A ADCY9 KLRF1 ZNF548 TBX1	1.15e-04	160	132	5	955acb023ce4ccfac5073c9d693db87db3856187
ToppCell	Basal_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CH25H APEX1 LRP1B SMO HS3ST4	1.15e-04	160	132	5	b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 CH25H PTPN14 PAPPA TBX1	1.29e-04	164	132	5	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 CH25H PTPN14 PAPPA TBX1	1.29e-04	164	132	5	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 CH25H PTPN14 PAPPA TBX1	1.29e-04	164	132	5	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 CH25H PTPN14 PAPPA TBX1	1.29e-04	164	132	5	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CH25H RMDN2 SLC40A1 PTPN14 AKR1C3	1.36e-04	166	132	5	1f39c7507ac6881aa1a30f8be22f98a1837d926b
ToppCell	390C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 MARCHF6 MBOAT2 LDLR MPND	1.57e-04	171	132	5	70963f79711fe6088d6d01b29206b17ab89e5e73
ToppCell	metastatic_Brain-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	TOPBP1 ERMP1 ZNF230 KCNQ5 PIK3R5	1.57e-04	171	132	5	0d14bc9688c427ba2265984987dc3eea195b19eb
ToppCell	390C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ASAH2 MARCHF6 LDLR MPND ASAH2B	1.61e-04	172	132	5	84d16cd7f618c94888920680bdc9e7130d73fd75
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 DYNC2H1 ARHGAP39 DNAH7 TMEM231	1.65e-04	173	132	5	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Lymphocytic-T\|bone_marrow / Manually curated celltypes from each tissue	TOPBP1 SLC40A1 BRCA2 UGGT2 CD302	1.70e-04	174	132	5	1e289b26e2c29dbad15b712a999b96c391a26129
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ZXDC MRC1 LDLR TUBGCP6 HEG1	1.75e-04	175	132	5	f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	GPR89B TFRC TMEM168 SCD SELENOI	1.79e-04	176	132	5	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	Healthy-RBC\|World / disease group, cell group and cell class	ESPN LRP1B MBOAT2 LOXHD1 EML1	1.84e-04	177	132	5	2ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ESPN MBOAT2 USH1G PIP5KL1 TBX1	1.89e-04	178	132	5	3d120458a0a56097532ebfa5fc6f77b52af2af2a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA8 FZD7 MFGE8 CD302 FZD2	1.99e-04	180	132	5	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	IIH-CD8-CD4_Treg\|IIH / Condition, Cell_class and T cell subcluster	CUL4A LRWD1 TOPBP1 ZNF230 BRCA2	1.99e-04	180	132	5	d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCell	severe-CD8+_T_naive\|severe / disease stage, cell group and cell class	DENND1A ZNF852 TUBD1 TMEM220 ZNF548	1.99e-04	180	132	5	94fe530367b170777f4051a4034cff06d80dbb83
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	ABCA8 KCNQ5 UGGT2 PAPPA TBX20	2.04e-04	181	132	5	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	AHI1-DT CFAP251 RGS22 DNAH7 TMEM231	2.09e-04	182	132	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NPY2R CYGB TCF25 CYP4X1 DISP2	2.09e-04	182	132	5	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.09e-04	182	132	5	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC1 TFRC MFGE8 AKR1C3 TBX20	2.20e-04	184	132	5	840fac463665ed18752f402f7d1ef2e5052bdf74
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RALGAPA2 LOXHD1 PIK3C2B CYP4X1 TBX1	2.20e-04	184	132	5	30ca56d64c961127e26122613e35aa2b46fde2df
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	MRC1 TFRC SCD AKR1C3 PKP2	2.20e-04	184	132	5	7fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.26e-04	185	132	5	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	CFAP251 RGS22 ARHGAP39 DNAH7 TMEM231	2.26e-04	185	132	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	AHI1-DT CFAP251 RGS22 DNAH7 TMEM231	2.26e-04	185	132	5	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.32e-04	186	132	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LAMB4 RGS22 LRP1B TCF25 SIGLEC11	2.32e-04	186	132	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYGB LRP1B ABCA8 MFGE8 CD302	2.32e-04	186	132	5	7582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	IL12RB1 DPP9 TOMM40L MPND BRD1	2.43e-04	188	132	5	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.43e-04	188	132	5	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	15-Distal-Mesenchymal-Pericyte\|Distal / Age, Tissue, Lineage and Cell class	CYGB MFGE8 KCNQ5 KCNQ3 PAPPA	2.43e-04	188	132	5	4963382e54aac06bf5047c7d725393db70667ee7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT ERMP1 EDIL3 DNAH7 PTPN14	2.43e-04	188	132	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THNSL1 ARHGAP39 FREM1 FZD7 IPO13	2.43e-04	188	132	5	c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.43e-04	188	132	5	5ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APEX1 NXPE2 MFGE8 OTC GPR89A	2.49e-04	189	132	5	be09a116ce0ea9ddfa0974806c6f805438e44660
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.49e-04	189	132	5	57ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.49e-04	189	132	5	ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMB4 AHI1-DT LRP1B PTPN14 LLGL2	2.49e-04	189	132	5	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MRC1 CD302 SIGLEC11 FZD2 DSE	2.49e-04	189	132	5	e4b2f00cb3675a4d94e8807d6ff99cc55f9ed233
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AHI1-DT CFAP251 DYNC2H1 RGS22 DNAH7	2.49e-04	189	132	5	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|IPF / Disease state, Lineage and Cell class	MRC1 PSME4 SCD AKR1C3 PKP2	2.55e-04	190	132	5	e539ebc0f4c5ee5dba86c614387be7d91338ad47
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.55e-04	190	132	5	169e600e95878000acf5d11f813f9028c7249646
ToppCell	343B-Epithelial_cells-Epithelial-F_(Ciliated)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.55e-04	190	132	5	0cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MRC1 DENND1A SLC40A1 TFRC PIK3R5	2.55e-04	190	132	5	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages\|bone_marrow / Manually curated celltypes from each tissue	MRC1 SLC40A1 SCD CYP4X1 PAPPA	2.55e-04	190	132	5	9db04555c98eca1df15d144fbb499e0ba06660d5
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DYNC2H1 DNAH7 BRCA2 EML1 TMEM231	2.55e-04	190	132	5	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AHI1-DT CFAP251 RGS22 DNAH7 TMEM231	2.62e-04	191	132	5	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AHI1-DT CFAP251 RGS22 DNAH7 TMEM231	2.62e-04	191	132	5	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AHI1-DT CFAP251 DYNC2H1 RGS22 DNAH7	2.62e-04	191	132	5	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	LAM-Epithelial-AirwayEpi\|LAM / Condition, Lineage and Cell class	CFAP251 RGS22 DNAH7 CYP4X1 TMEM231	2.68e-04	192	132	5	7404fc65be3b7bd09447725b43fa31819004dfee
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CYGB KCNQ5 CYP4X1 KCNQ3 PAPPA	2.68e-04	192	132	5	55f95454399fd533df75db06584eaa48d6ee3830
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	DYNC2H1 ABCA8 CYP4X1 UGGT2 PAPPA	2.68e-04	192	132	5	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	UBR4 LDLR FREM1 PTPN14 PNPLA8	2.68e-04	192	132	5	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	343B-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LLGL2 DPP9 TOMM40L MPND BRD1	2.68e-04	192	132	5	445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	AHI1-DT CFAP251 DYNC2H1 RGS22 DNAH7	2.68e-04	192	132	5	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYGB LRP1B ABCA8 MFGE8 FZD2	2.68e-04	192	132	5	11867f30f0b420c18cb0b34d3990237aa737a0e8
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	AHI1-DT CFAP251 DYNC2H1 RGS22 DNAH7	2.68e-04	192	132	5	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.75e-04	193	132	5	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AHI1-DT CFAP251 DYNC2H1 RGS22 DNAH7	2.75e-04	193	132	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	CFAP251 DYNC2H1 RGS22 DNAH7 TMEM231	2.75e-04	193	132	5	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR4 SEC31A LDLR SLC40A1 DISP2	2.75e-04	193	132	5	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AHI1-DT CFAP251 DYNC2H1 RGS22 DNAH7	2.75e-04	193	132	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	facs-Heart-LA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CH25H CYGB SCD CD302 TBX20	2.75e-04	193	132	5	124364adb3ded77282d449dd2cb039e6f2403a39
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR4 SEC31A LDLR SLC40A1 DISP2	2.75e-04	193	132	5	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	Control-NK_CD56bright\|Control / Disease condition and Cell class	CYGB TCIRG1 ERMP1 KLRF1 UGGT2	2.75e-04	193	132	5	8b1e7a226a6057e1097c1525984127b54e823876
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	MRC1 SCD AKR1C3 PKP2 HS3ST4	2.75e-04	193	132	5	03a43b6d235fd47488a6a61efc311a34b232c0f4
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERMP1 EDIL3 ABCA8 SCD IPO13	2.81e-04	194	132	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	PCW_07-8.5\|World / Celltypes from embryonic and fetal-stage human lung	USP46 EDIL3 BRCA2 SCD ATRNL1	2.81e-04	194	132	5	5759c83308df017f1faae248e9b85388e25254f0
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	MRC1 CH25H TFRC PKP2 PIK3R5	2.81e-04	194	132	5	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EDIL3 SLC40A1 ABCA8 FREM1 FZD7	2.81e-04	194	132	5	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
Disease	Meckel syndrome (implicated_via_orthology)	NPHP4 TBC1D32 TMEM231	4.09e-06	8	125	3	DOID:0050778 (implicated_via_orthology)
Disease	partial epilepsy	ADCY9 FZD7 TBC1D32	4.83e-05	17	125	3	EFO_0004263
Disease	congenital heart disease (is_marker_for)	TBX20 TBX1	1.06e-04	4	125	2	DOID:1682 (is_marker_for)
Disease	congenital heart disease (is_implicated_in)	NPHP4 TBX20 TBX1	1.41e-04	24	125	3	DOID:1682 (is_implicated_in)
Disease	VACTERL association (implicated_via_orthology)	DYNC2H1 TBC1D32	2.64e-04	6	125	2	DOID:14679 (implicated_via_orthology)
Disease	cataract	CPT1A LRP1B KCNQ5 SCD PIP5KL1	3.44e-04	141	125	5	MONDO_0005129
Disease	colon cancer (is_implicated_in)	ATR LRP1B PIK3R5	4.78e-04	36	125	3	DOID:219 (is_implicated_in)
Disease	cervix carcinoma (is_implicated_in)	ERAP1 APEX1	7.84e-04	10	125	2	DOID:2893 (is_implicated_in)
Disease	long QT syndrome (implicated_via_orthology)	KCNQ5 KCNQ3	7.84e-04	10	125	2	DOID:2843 (implicated_via_orthology)
Disease	Ciliopathies	DYNC2H1 NPHP4 USH1G TMEM231	1.25e-03	110	125	4	C4277690
Disease	free cholesterol to total lipids in small HDL percentage	CPT1A LDLR TOMM40L	1.33e-03	51	125	3	EFO_0022285
Disease	liver cirrhosis (implicated_via_orthology)	CYGB SMO	1.35e-03	13	125	2	DOID:5082 (implicated_via_orthology)
Disease	tetralogy of Fallot (is_implicated_in)	TBX20 TBX1	1.35e-03	13	125	2	DOID:6419 (is_implicated_in)
Disease	developmental and epileptic encephalopathy (implicated_via_orthology)	KCNQ5 KCNQ3	1.35e-03	13	125	2	DOID:0112202 (implicated_via_orthology)
Disease	cortisol measurement, response to corticosteroid, response to synacthen	LRP1B GBA3	1.35e-03	13	125	2	EFO_0005843, EFO_0009175, GO_0031960
Disease	neuroimaging measurement, brain volume measurement	MRC1 ATR SERPINA2 PAPPA EML1 TUBD1	1.41e-03	286	125	6	EFO_0004346, EFO_0006930
Disease	ventricular septal defect (is_implicated_in)	TBX20 TBX1	1.57e-03	14	125	2	DOID:1657 (is_implicated_in)
Disease	Hepatomegaly	CYGB MBOAT2 SESN2	1.57e-03	54	125	3	C0019209
Disease	ovarian cancer (is_implicated_in)	APEX1 TFRC BRCA2	1.75e-03	56	125	3	DOID:2394 (is_implicated_in)
Disease	pre-eclampsia (biomarker_via_orthology)	TLR3 AKR1C3	2.32e-03	17	125	2	DOID:10591 (biomarker_via_orthology)
Disease	mitochondrial DNA measurement	CFAP251 TBRG4 APEX1 EDIL3 LDLR TUBGCP6	2.80e-03	328	125	6	EFO_0006312
Disease	Congenital hernia of foramen of Morgagni	FREM1 KCNQ5	2.90e-03	19	125	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	FREM1 KCNQ5	2.90e-03	19	125	2	C0265700
Disease	iron biomarker measurement, transferrin measurement	SLC40A1 TFRC	3.22e-03	20	125	2	EFO_0004461, EFO_0006341
Disease	cortisol measurement	SERPINA2 LDLR	3.22e-03	20	125	2	EFO_0005843
Disease	Severe Combined Immunodeficiency	TFRC TBX1	3.22e-03	20	125	2	C0085110
Disease	Congenital diaphragmatic hernia	FREM1 KCNQ5	3.55e-03	21	125	2	C0235833

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLWAAYHGNLESLRL	USH1G	36	Q495M9
AHSYWLLKRLSRNGA	BRD1	476	O95696
LLAKWYEKFFGRLSH	ALG1	176	Q9BT22
LSALYALWSLSRHAA	ACOX3	591	O15254
TSAFLWLPRLHISSY	TBC1D32	1096	Q96NH3
YTSKLWSTFHRPELV	AKR1C3	81	P42330
ETRFYWHKGLLGLSN	ASAH2B	101	P0C7U1
GAIIWFLYKKHSDSR	CD302	186	Q8IX05
EALRQIYLSGLHSWK	CPT1A	26	P50416
SLSFSWLSKALYHVT	AHI1-DT	251	P0C7V0
KNVGWRLDYFLLSHS	APEX1	276	P27695
WFTSRLELYSLQHSL	DISP2	946	A7MBM2
SFYVRAHKGSTLSQW	ERMP1	801	Q7Z2K6
YHRKIISWFGDSPLA	ATG4C	196	Q96DT6
HVWFYGRLKGLSAAV	ABCA7	901	Q8IZY2
QLASYALAHSLGRWL	ABHD16B	96	Q9H3Z7
SIVNWYSHLKLGAIR	CFAP251	531	Q8TBY9
HRILGYRWKISVFSG	MSANTD5	121	A0A3B3IT52
RGYPCSLWKLFHTLT	QSOX2	426	Q6ZRP7
LHYRTSSLRWNSGAK	ARHGAP39	196	Q9C0H5
SFSYTRIWSKLKNHV	NPY2R	236	P49146
SWLSYHLLKATDLGL	PCDHB1	601	Q9Y5F3
THLFTASYDKRIILW	LRWD1	406	Q9UFC0
EKVHWGTRYAITIAF	OGFOD3	291	Q6PK18
HLWKTLRYPGRTFST	PIP5KL1	361	Q5T9C9
HKTSGADRLSLIYSW	LRP1B	3241	Q9NZR2
WDLQGSRVLYHFLSS	LLGL2	216	Q6P1M3
LLAAIWFRTYLHSSK	MBOAT2	36	Q6ZWT7
ITASSSYKTWGLHLF	MFGE8	246	Q08431
WLVLLYGHKRLSYQT	GPR137	46	Q96N19
ETRFYWHKGLLGLSN	ASAH2	716	Q9NR71
AHSKELITAWYIGFL	KCNQ3	256	O43525
AHSKELITAWYIGFL	KCNQ5	261	Q9NR82
FAASRGHTKVLSWLL	ESPN	246	B1AK53
FYKIRVWHDKRSSGS	LOXHD1	486	Q8IVV2
SLDGYFHLWKARSTL	DCAF12L2	281	Q5VW00
YLWHVPLTFITSKSD	ERAP1	561	Q9NZ08
EHYSSLKGLTLSWIG	OTC	181	P00480
GTFSWGDLHTLKVRY	FREM1	836	Q5H8C1
SGKTLHSWRKFYTRL	FZD2	541	Q14332
WAHLFSSLRGYLKSL	NOD1	621	Q9Y239
GLVTSIGTAIRYWFH	MARCHF6	81	O60337
TLHTEFLWYDGSLKS	DSE	366	Q9UL01
LSFRDKLYWTHGYVL	TUBGCP6	561	Q96RT7
SWLHFYRTAASSPLL	HEG1	286	Q9ULI3
SYGNIVWTLLHIRSA	OR6Q1	221	Q8NGQ2
SLFLRGLSLVGWYHS	MPND	336	Q8N594
ISYIFILFTVWKHSS	OR4F15	216	Q8NGB8
GYIEHFSLWKVARTQ	PAPPA	251	Q13219
FFRWHYQSIGSTLKK	RALGAPA2	101	Q2PPJ7
TYRHFFGRTWKTTVK	NPHP4	66	O75161
SDLRVTHYFFWLLKD	PIK3C2B	946	O00750
SWRRFYHRLSHSSKG	FZD7	556	O75084
NHSIWGSSSKIYLLA	DYNC2H1	2456	Q8NCM8
ASSTHRALFGLQKWY	EDIL3	176	O43854
TSLALVDYISFHGKW	SERPINA2	206	P20848
SASWAGYLITKVRHD	ATR	1491	Q13535
SVTLHWYKILLGISG	KLRF1	31	Q9NZS2
ITSFSHQWAKTLKYR	BRCA2	1556	P51587
IKQLGLTHYRFSLSW	GBA3	66	Q9H227
EILGVLNSSSRYFHW	GPR89A	61	B7ZAQ6
EILGVLNSSSRYFHW	GPR89B	61	P0CG08
WDGLRSIIHGSRKYS	DPP9	31	Q86TI2
ASRHSGRKLTWLYQL	CUL1	571	Q13616
LLQHWSEYIKTFGTA	CUL4A	336	Q13619
WAKLRGLIYSHVTAA	CYGB	151	Q8WWM9
AGHDTLAASISWILY	CYP4X1	316	Q8N118
WRKSFLAASSYIRDH	DNAH7	256	Q8WXX0
ELFYSQHFSGRKLTW	CUL2	541	Q13617
KLYARHYAWTSLALT	ADCY9	166	O60503
WTILKESGFARYLHS	ATRNL1	511	Q5VV63
KLTLWSTVLSTYHFG	IL12RB1	426	P42701
HTSTSKRHWLRFFYL	TMEM259	396	Q4ZIN3
YHQWLSTVRKGSGAI	DENND1A	401	Q8TEH3
SFILSHWEKYNTGIL	SELENOI	166	Q9C0D9
TLFLHLGWLSYSKAQ	LAMB4	6	A4D0S4
IIVTCGKSHLYFWTL	EML1	386	O00423
SYITHIDWDSRGKLL	EML6	1126	Q6ZMW3
WLFSTNHKDIGTLYL	MT-CO1	6	P00395
VLSHVSGLGWLASYL	DHRS1	281	Q96LJ7
IGSTVYSKHWLFGVL	SAAL1	26	Q96ER3
YSKHWLFGVLSGLIQ	SAAL1	31	Q96ER3
YFGASALHIKISRYW	IPO13	76	O94829
APYFTHWDKILGTLR	CH25H	251	O95992
ASWSAIRIGIYALHL	HS3ST4	326	Q9Y661
KWNSFTILLIHSGGY	FPGT	116	O14772
VWHGTLSKLLGSLYA	TBRG4	141	Q969Z0
RLITASGSYHKLFWL	MRC1	701	P22897
KHYWRISHISLQRGF	PNPLA8	36	Q9NP80
TSFWRLHYLLLHTDG	SESN2	91	P58004
ISHWKAFGDILYRSE	TRIM48	181	Q8IWZ4
ISYLSKEEWRLFHRS	NXPE2	276	Q96DL1
STKYASAELKFWHLR	RGS22	516	Q8NE09
IYSDLADLTLKHGWR	NT5DC3	391	Q86UY8
LRETHYFGLWFLSKS	PTPN14	56	Q15678
GTAGISLLLLWYHKV	RMDN2	16	Q96LZ7
FLLYLGHSLSTWGDR	SLC40A1	26	Q9NP59
STFHVLIYGWKRAFE	STEAP2	406	Q8NFT2
WLEGYLSSLHLKAFT	TFRC	466	P02786
SSDSSFWRLVYHIKI	TCL1A	86	P56279
FTSLYRHLPASLEWI	ABCA8	346	O94911
TLSGFHSRTIYDIAW	CIAO1	246	O76071
GFVIYSWRKSTTHLG	CLECL1	26	Q8IZS7
EISSSHGFLVWRYLL	UHRF2	596	Q96PU4
AYTTFTWAGLLKHLR	TUBD1	286	Q9UJT1
GKWFSQLTLGIAYLH	TSSK4	126	Q6SA08
SFYWNVSVHRVLGFK	TLR3	731	O15455
GWAFTTSYKLKRHLQ	ZXDC	216	Q2QGD7
TVWAVGLASYLLHRT	TMEM220	71	Q6QAJ8
LLLKAASTYHRFLTW	PIK3R5	101	Q8WYR1
RASWLYKHIFPFSLI	SLC27A3	446	Q5K4L6
TFALAELRKSWYSTH	THNSL1	36	Q8IYQ7
TAGAHRLWSHRSYKA	SCD	116	O00767
SAFKLRDTHLWYFVI	TMEM168	281	Q9H0V1
RILYSKTEHLGLNWF	PSME4	151	Q14997
KTSYFHLLTWSLPFV	SMO	356	Q99835
RGHYITIVKSHGFWL	USP46	311	P62068
KAFYWSSHLIGHRRI	ZNF852	166	Q6ZMS4
VAFRSHGFWLKRSSY	TMEM231	41	Q9H6L2
TLAGKYSAVHWVATL	TOMM40L	196	Q969M1
CGKSFRWSSYLLIHQ	ZNF230	341	Q9UIE0
GELFRYNSSLVKHWR	ZNF548	371	Q8NEK5
RYAYHRSSWLVAGKA	TBX20	161	Q9UMR3
KSIASTARWYLLRHL	TTC37	1516	Q6PGP7
RYAFHSSSWLVAGKA	TBX1	171	O43435
GYWASHLLRRKYHIS	UGGT2	1376	Q9NYU1
PFLTKTWHSLRALVY	nan	106	Q6AWC8
ATFSSSHRYHKLIWG	SEC31A	61	O94979
ITSAHWKVYLAARGV	UBR4	4191	Q5T4S7
SVAAGKWVLHRSYLE	TOPBP1	1321	Q92547
ASKAASVLLYSLWAH	PKP2	836	Q99959
LYLGRSHFLWKEPAT	TCF25	501	Q9BQ70
ELHYASLSFQGLRLW	SIGLEC11	641	Q96RL6
TASYLRLWALSLAHA	TCIRG1	731	Q13488
NRITWLFHYSALLSA	TDH	116	Q8IZJ6
GKSFAWRSTLVEHVY	ZNF764	181	Q96H86
LSGRLYWVDSKLHSI	LDLR	571	P01130