Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC7A13 SLC35C2 NDUFA10 SLCO1B1 SLC1A4 SLC26A8 ABCC8 SLC35A2 SLC47A1 CTNS ATP12A SLC4A4 ABCC10 SLC35A5	1.11e-05	477	146	14	GO:0022804
GeneOntologyMolecularFunction	transporter activity	ANO2 SLC7A13 APOA5 FLVCR1 SLC35C2 NDUFA10 PEX5L SLCO1B1 SLC1A4 SLC26A8 SLC35B4 ABCC8 SLC35A2 SCN10A STARD3 NIPAL2 SLC47A1 ATP11C CTNS ATP12A SLC4A4 LMBRD1 ABCC10 SLC35A5	2.10e-05	1289	146	24	GO:0005215
GeneOntologyMolecularFunction	pyrimidine nucleotide-sugar transmembrane transporter activity	SLC35B4 SLC35A2 SLC35A5	6.05e-05	11	146	3	GO:0015165
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC7A13 SLC35C2 SLCO1B1 SLC1A4 SLC26A8 SLC35A2 SLC47A1 CTNS SLC4A4 SLC35A5	6.61e-05	296	146	10	GO:0015291
GeneOntologyMolecularFunction	antiporter activity	SLC7A13 SLC35C2 SLC26A8 SLC35A2 SLC47A1 SLC4A4 SLC35A5	7.05e-05	138	146	7	GO:0015297
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	SLC1A4 SLC26A8 SLC47A1 CTNS ABCC10	8.35e-05	61	146	5	GO:1901682
GeneOntologyMolecularFunction	nucleotide-sugar transmembrane transporter activity	SLC35B4 SLC35A2 SLC35A5	1.31e-04	14	146	3	GO:0005338
GeneOntologyMolecularFunction	L-cystine transmembrane transporter activity	SLC1A4 CTNS	3.16e-04	4	146	2	GO:0015184
GeneOntologyMolecularFunction	transmembrane transporter activity	ANO2 SLC7A13 FLVCR1 SLC35C2 NDUFA10 PEX5L SLCO1B1 SLC1A4 SLC26A8 SLC35B4 ABCC8 SLC35A2 SCN10A NIPAL2 SLC47A1 CTNS ATP12A SLC4A4 ABCC10 SLC35A5	3.80e-04	1180	146	20	GO:0022857
GeneOntologyMolecularFunction	ADP binding	MYO7A MSH2 ABCC8 PRKAG1	4.16e-04	48	146	4	GO:0043531
GeneOntologyMolecularFunction	centromeric DNA binding	MSH2 ZW10	1.09e-03	7	146	2	GO:0019237
GeneOntologyBiologicalProcess	pyrimidine nucleotide-sugar transmembrane transport	SLC35C2 SLC35B4 SLC35A2 SLC35A5	1.11e-06	12	145	4	GO:0090481
GeneOntologyBiologicalProcess	nucleotide-sugar transmembrane transport	SLC35C2 SLC35B4 SLC35A2 SLC35A5	1.59e-06	13	145	4	GO:0015780
GeneOntologyBiologicalProcess	L-cystine transport	SLC7A13 SLC1A4 CTNS	6.70e-06	6	145	3	GO:0015811
GeneOntologyBiologicalProcess	vesicle tethering to endoplasmic reticulum	STARD3 STARD3NL	4.91e-05	2	145	2	GO:0099044
GeneOntologyBiologicalProcess	organic anion transport	SLC7A13 SLC35C2 SLCO1B1 SLC1A4 ADORA2A SLC26A8 SLC35B4 ABCC8 SLC35A2 SLC47A1 CTNS SLC4A4 ABCC10	7.26e-05	515	145	13	GO:0015711
GeneOntologyBiologicalProcess	sulfur amino acid transport	SLC7A13 SLC1A4 CTNS	9.24e-05	13	145	3	GO:0000101
GeneOntologyBiologicalProcess	sulfur compound transport	SLC7A13 SLC1A4 SLC26A8 SLC47A1 CTNS	9.43e-05	65	145	5	GO:0072348
GeneOntologyCellularComponent	upper tip-link density	MYO7A USH1C	4.78e-05	2	145	2	GO:1990435
GeneOntologyCellularComponent	COPI vesicle coat	COPB1 COPG1 COPG2	8.88e-05	13	145	3	GO:0030126
GeneOntologyCellularComponent	stereocilia tip-link density	MYO7A USH1C	1.43e-04	3	145	2	GO:1990427
GeneOntologyCellularComponent	stereocilia tip link	MYO7A USH1C	1.43e-04	3	145	2	GO:0002140
GeneOntologyCellularComponent	endoplasmic reticulum membrane	PIGN MINAR2 PIGP COPB1 COPG1 RTN4 RHBDD2 COPG2 PIGU LMBR1L SLC35B4 SLC35A2 STARD3 ATP11C STARD3NL ZW10 RNF139 ERMARD LMBRD1 FAM8A1 GSG1	2.34e-04	1293	145	21	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	PIGN MINAR2 PIGP COPB1 COPG1 RTN4 RHBDD2 COPG2 PIGU LMBR1L SLC35B4 SLC35A2 STARD3 ATP11C STARD3NL ZW10 RNF139 ERMARD LMBRD1 FAM8A1 GSG1	2.49e-04	1299	145	21	GO:0098827
GeneOntologyCellularComponent	endoplasmic reticulum-endosome membrane contact site	STARD3 STARD3NL	2.84e-04	4	145	2	GO:0140284
GeneOntologyCellularComponent	COPI-coated vesicle membrane	COPB1 COPG1 COPG2	2.92e-04	19	145	3	GO:0030663
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	PIGN MINAR2 PIGP COPB1 COPG1 RTN4 RHBDD2 COPG2 PIGU LMBR1L SLC35B4 SLC35A2 STARD3 ATP11C STARD3NL ZW10 RNF139 ERMARD LMBRD1 FAM8A1 GSG1	3.32e-04	1327	145	21	GO:0042175
GeneOntologyCellularComponent	stereocilia coupling link	MYO7A USH1C	1.30e-03	8	145	2	GO:0002139
GeneOntologyCellularComponent	COPI-coated vesicle	COPB1 COPG1 COPG2	1.53e-03	33	145	3	GO:0030137
GeneOntologyCellularComponent	Golgi membrane	CHST5 COPB1 COPG1 ASAH2 NDST4 RHBDD2 COPG2 FKTN SLC35B4 GALNT8 SLC35A2 GCC1 SLC35A5	1.56e-03	721	145	13	GO:0000139
GeneOntologyCellularComponent	endoplasmic reticulum protein-containing complex	PIGP PIGU ZW10 RNF139 FAM8A1	1.80e-03	125	145	5	GO:0140534
Domain	ARM-type_fold	IPO5 COPB1 COPG1 INTS7 DOCK8 CIP2A DOCK9 COPG2 RICTOR NBEA IPO4 ARFGEF3 MROH8 EIF3K PPP6R3	6.35e-08	339	145	15	IPR016024
Domain	LMBR1	LMBR1 LMBR1L LMBRD1	1.82e-06	4	145	3	PF04791
Domain	LMBR1-like_membr_prot	LMBR1 LMBR1L LMBRD1	1.82e-06	4	145	3	IPR006876
Domain	ARM-like	IPO5 COPB1 COPG1 INTS7 DOCK8 CIP2A COPG2 RICTOR NBEA IPO4 PPP6R3	8.61e-06	270	145	11	IPR011989
Domain	LIMR	LMBR1 LMBR1L	5.99e-05	2	145	2	IPR008075
Domain	Coatomer_g_Cpla	COPG1 COPG2	5.99e-05	2	145	2	IPR032154
Domain	-	COPG1 COPG2	5.99e-05	2	145	2	2.60.40.1480
Domain	MENTAL	STARD3 STARD3NL	5.99e-05	2	145	2	PF10457
Domain	MENTAL	STARD3 STARD3NL	5.99e-05	2	145	2	PS51439
Domain	COP-gamma_platf	COPG1 COPG2	5.99e-05	2	145	2	PF08752
Domain	Coatomer_g_Cpla	COPG1 COPG2	5.99e-05	2	145	2	PF16381
Domain	Coatomer_gsu_app_Ig-like-sub	COPG1 COPG2	5.99e-05	2	145	2	IPR013040
Domain	MENTAL	STARD3 STARD3NL	5.99e-05	2	145	2	IPR019498
Domain	Coatomer_gsu	COPG1 COPG2	5.99e-05	2	145	2	IPR017106
Domain	Clathrin/coatomer_adapt-like_N	COPB1 COPG1 COPG2	1.95e-04	15	145	3	IPR002553
Domain	Adaptin_N	COPB1 COPG1 COPG2	1.95e-04	15	145	3	PF01602
Domain	-	IPO5 COPB1 COPG1 INTS7 CIP2A COPG2 RICTOR IPO4	3.47e-04	222	145	8	1.25.10.10
Domain	Clathrin_a/coatomer_app_sub_C	COPG1 COPG2	3.56e-04	4	145	2	IPR015873
Domain	-	COPG1 COPG2	3.56e-04	4	145	2	3.30.310.30
Domain	Nuc_sug_transp	SLC35A2 SLC35A5	5.89e-04	5	145	2	PF04142
Domain	Nuc_sug_transpt	SLC35A2 SLC35A5	5.89e-04	5	145	2	IPR007271
Domain	DUF3398	DOCK8 DOCK9	8.80e-04	6	145	2	PF11878
Domain	DOCK_C/D_N	DOCK8 DOCK9	8.80e-04	6	145	2	IPR021816
Domain	Cadherin_CS	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	1.61e-03	109	145	5	IPR020894
Domain	Coatomer/calthrin_app_sub_C	COPG1 COPG2	1.63e-03	8	145	2	IPR009028
Domain	Alkaline_phosphatase_core	PIGN ARSB ENPP5	1.76e-03	31	145	3	IPR017850
Domain	Alkaline_Pase-like_a/b/a	PIGN ARSB ENPP5	1.76e-03	31	145	3	IPR017849
Domain	-	PIGN ARSB ENPP5	1.76e-03	31	145	3	3.40.720.10
Domain	CADHERIN_1	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	1.89e-03	113	145	5	PS00232
Domain	Cadherin	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	1.89e-03	113	145	5	PF00028
Domain	CADHERIN_2	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	1.96e-03	114	145	5	PS50268
Domain	-	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	1.96e-03	114	145	5	2.60.40.60
Domain	CA	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	2.04e-03	115	145	5	SM00112
Domain	Cadherin-like	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	2.12e-03	116	145	5	IPR015919
Domain	HEAT_REPEAT	IPO5 COPG1 COPG2 IPO4	2.15e-03	70	145	4	PS50077
Domain	Cadherin	DCHS2 DSC2 PCDHGC5 PCDHB9 CELSR3	2.28e-03	118	145	5	IPR002126
Domain	Phosphodiest/P_Trfase	PIGN ENPP5	2.59e-03	10	145	2	IPR002591
Domain	Phosphodiest	PIGN ENPP5	2.59e-03	10	145	2	PF01663
Domain	DHR-1_domain	DOCK8 DOCK9	3.14e-03	11	145	2	IPR027007
Domain	DHR_2	DOCK8 DOCK9	3.14e-03	11	145	2	PS51651
Domain	DHR_1	DOCK8 DOCK9	3.14e-03	11	145	2	PS51650
Domain	DHR-2	DOCK8 DOCK9	3.14e-03	11	145	2	PF06920
Domain	DOCK	DOCK8 DOCK9	3.14e-03	11	145	2	IPR026791
Domain	DOCK_C	DOCK8 DOCK9	3.14e-03	11	145	2	IPR010703
Domain	DOCK-C2	DOCK8 DOCK9	3.14e-03	11	145	2	PF14429
Domain	DHR-2	DOCK8 DOCK9	3.14e-03	11	145	2	IPR027357
Domain	Coatomer/clathrin_app_Ig-like	COPG1 COPG2	3.75e-03	12	145	2	IPR013041
Domain	IMPORTIN_B_NT	IPO5 IPO4	5.12e-03	14	145	2	PS50166
Domain	Importin-beta_N	IPO5 IPO4	7.54e-03	17	145	2	IPR001494
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	DSC2 COPB1 COPG1 INTS7 CIP2A FLVCR1 RTN4 LMBR1 COPG2 MSH2 IPO4 FAS TSPAN3 ARFGEF3 LMBR1L P3H1 SLC47A1 ZW10 FAM8A1 PPP6R3	4.33e-09	942	149	20	31073040
Pubmed	Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism.	LMBR1 LMBR1L LMBRD1	7.71e-08	3	149	3	19136951
Pubmed	LMBRD1: the gene for the cblF defect of vitamin B₁₂ metabolism.	LMBR1 LMBR1L LMBRD1	7.71e-08	3	149	3	20446115
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PLEKHG4 RTN4 RHBDD2 COPG2 CHD8 NDUFA10 FAS PIGU TTF1 TMEM177 SLC35B4 SLC35A2 ATP11C STARD3NL ZW10 ATP12A SLC4A4 FAM8A1 ABCC10	1.57e-07	1061	149	19	33845483
Pubmed	Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum.	COPB1 COPG1 COPG2	1.53e-06	6	149	3	11884415
Pubmed	Identification and characterization of novel isoforms of COP I subunits.	COPB1 COPG1 COPG2	1.53e-06	6	149	3	11056392
Pubmed	Novel isotypic gamma/zeta subunits reveal three coatomer complexes in mammals.	COPB1 COPG1 COPG2	4.25e-06	8	149	3	14729954
Pubmed	In vivo assembly of coatomer, the COP-I coat precursor.	COPB1 COPG1 COPG2	4.25e-06	8	149	3	8940050
Pubmed	A single binding site for dilysine retrieval motifs and p23 within the gamma subunit of coatomer.	COPB1 COPG1 COPG2	6.35e-06	9	149	3	9751720
Pubmed	COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP.	COPB1 COPG1 COPG2	6.35e-06	9	149	3	10921873
Pubmed	Integral and associated lysosomal membrane proteins.	STARD3 ATP11C ZFYVE26 CTNS STARD3NL ABCC10	1.80e-05	126	149	6	17897319
Pubmed	Functional characterization of the MENTAL domain.	STARD3 STARD3NL	1.82e-05	2	149	2	15718238
Pubmed	MENTHO, a MLN64 homologue devoid of the START domain.	STARD3 STARD3NL	1.82e-05	2	149	2	12393907
Pubmed	Touché! STARD3 and STARD3NL tether the ER to endosomes.	STARD3 STARD3NL	1.82e-05	2	149	2	27068960
Pubmed	Triggering receptor expressed on myeloid cells-1 (TREM-1) deficiency augments BAFF production to promote lupus progression.	FAS TREM1	1.82e-05	2	149	2	28089248
Pubmed	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.	SPEG OBSCN	1.82e-05	2	149	2	15185077
Pubmed	Pathogenesis of lupus nephritis: RIP3 dependent necroptosis and NLRP3 inflammasome activation.	RIPK3 FAS	1.82e-05	2	149	2	31133359
Pubmed	TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons.	ANO2 SCN10A	1.82e-05	2	149	2	30843875
Pubmed	MLN64 and MENTHO, two mediators of endosomal cholesterol transport.	STARD3 STARD3NL	1.82e-05	2	149	2	16709157
Pubmed	Subcellular localization of UDP-GlcNAc, UDP-Gal and SLC35B4 transporters.	SLC35B4 SLC35A2	1.82e-05	2	149	2	21918738
Pubmed	CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system.	CHST5 SERPINA3 COPG1 ZGRF1 ZFP57 LMBR1L SLC35B4 ENPP5 ZFYVE26 RNF139	2.17e-05	440	149	10	35156780
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	IPO5 COPB1 COPG1 CIP2A RTN4 COPG2 NBEA IPO4 ZW10 WIPI2	2.58e-05	449	149	10	31732153
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	COPG1 COPG2 HPS3 EIF3K PRR14L WDR62	3.14e-05	139	149	6	25476789
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ST20 DSC2 COPB1 COPG1 FLVCR1 KDM3B MUC16 COPG2 RICTOR NBEA IPO4 ARFGEF3 GCC1	3.23e-05	777	149	13	35844135
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	DSC2 COPG1 CIP2A RTN4 RHBDD2 COPG2 PIGU SLC35A2 PRR14L ZW10 WIPI2	3.63e-05	568	149	11	37774976
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	IPO5 COPB1 COPG1 COPG2 MSH2	3.76e-05	87	149	5	17148452
Pubmed	Novel mutations of MYO7A and USH1G in Israeli Arab families with Usher syndrome type 1.	MYO7A USH1C	5.45e-05	3	149	2	22219650
Pubmed	Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.	COPB1 COPG1	5.45e-05	3	149	2	12134073
Pubmed	Differential distribution of harmonin isoforms and their possible role in Usher-1 protein complexes in mammalian photoreceptor cells.	MYO7A USH1C	5.45e-05	3	149	2	14578428
Pubmed	Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice.	FAS TLR2	5.45e-05	3	149	2	24086313
Pubmed	Up-regulated SAMD9L modulated by TLR2 and HIF-1α as a promising biomarker in tuberculosis.	SAMD9L TLR2	5.45e-05	3	149	2	35388602
Pubmed	Myosin 7 and its adaptors link cadherins to actin.	MYO7A USH1C	5.45e-05	3	149	2	28660889
Pubmed	In Vivo Suppression of Autophagy via Lentiviral shRNA Targeting Atg5 Improves Lupus-Like Syndrome.	FAS TREM1	5.45e-05	3	149	2	32462028
Pubmed	Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus.	COPG1 COPG2	5.45e-05	3	149	2	11893085
Pubmed	Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2.	TLR2 TLN2	5.45e-05	3	149	2	16188968
Pubmed	mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation.	RICTOR SCN10A	5.45e-05	3	149	2	35579957
Pubmed	Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus.	FAS TLR2	5.45e-05	3	149	2	19841185
Pubmed	Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids.	MYO7A USH1C	5.45e-05	3	149	2	20639393
Pubmed	Genetic analysis of Tunisian families with Usher syndrome type 1: toward improving early molecular diagnosis.	MYO7A USH1C	5.45e-05	3	149	2	27440999
Pubmed	'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles.	COPB1 COPG2	5.45e-05	3	149	2	1898986
Pubmed	Site-specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles.	COPB1 COPG1	5.45e-05	3	149	2	10720466
Pubmed	Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune Response.	MSH2 TLR2	5.45e-05	3	149	2	34111601
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	RTN4 RHBDD2 NBEA PIGU HPS3 ARFGEF3 SLC35A2 STARD3 GCC1 ZW10	6.78e-05	504	149	10	34432599
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	DYM COPG1 VWA8 INTS7 FLVCR1 RTN4 COPG2 CEP250 EIF3K GCC1 DNA2 FAM8A1	1.05e-04	754	149	12	33060197
Pubmed	Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells.	MYO7A USH1C	1.09e-04	4	149	2	16481439
Pubmed	Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation.	MYO7A USH1C	1.09e-04	4	149	2	30275467
Pubmed	Myosin VII, USH1C, and ANKS4B or USH1G Together Form Condensed Molecular Assembly via Liquid-Liquid Phase Separation.	MYO7A USH1C	1.09e-04	4	149	2	31644917
Pubmed	X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C.	FAS ATP11C	1.09e-04	4	149	2	21518881
Pubmed	GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23.	COPB1 COPG2	1.09e-04	4	149	2	10318838
Pubmed	Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.	RIPK3 TLR2	1.09e-04	4	149	2	14749364
Pubmed	MYD88-dependent and -independent activation of TREM-1 via specific TLR ligands.	TLR2 TREM1	1.09e-04	4	149	2	19904768
Pubmed	Selective amplification and cloning of four new members of the G protein-coupled receptor family.	HTR1D ADORA2A	1.09e-04	4	149	2	2541503
Pubmed	Analysis of subcellular localization of Myo7a, Pcdh15 and Sans in Ush1c knockout mice.	MYO7A USH1C	1.09e-04	4	149	2	21156003
Pubmed	Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor.	HTR1D ADORA2A	1.09e-04	4	149	2	1662665
Pubmed	STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.	STARD3 STARD3NL	1.09e-04	4	149	2	24105263
Pubmed	Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16.	MUC16 TLR2	1.09e-04	4	149	2	25563498
Pubmed	Adenosine receptor 2a agonists target mouse CD11c+T-bet+ B cells in infection and autoimmunity.	FAS ADORA2A	1.09e-04	4	149	2	35064115
Pubmed	Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.	COPB1 COPG1 FLVCR1 COPG2 ZW10	1.31e-04	113	149	5	30352685
Pubmed	Defining the membrane proteome of NK cells.	IPO5 PIGN COPB1 DOCK8 DOCK9 MSH2 IPO4 PIGU SLC1A4 P3H1 PRKAG1 EIF3K STARD3NL ZW10 LMBRD1	1.57e-04	1168	149	15	19946888
Pubmed	TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury.	TLR2 TREM1	1.81e-04	5	149	2	23844229
Pubmed	Toll-like receptors 2 and 4 are differentially involved in Fas dependent apoptosis in Peyer's patch and the liver at an early stage after bile duct ligation in mice.	FAS TLR2	1.81e-04	5	149	2	16118350
Pubmed	Interactions in the network of Usher syndrome type 1 proteins.	MYO7A USH1C	1.81e-04	5	149	2	15590703
Pubmed	Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.	MYO7A USH1C	1.81e-04	5	149	2	20332152
Pubmed	Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient population.	MYO7A USH1C	1.81e-04	5	149	2	15660226
Pubmed	Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.	IPO5 IPO4	1.81e-04	5	149	2	27528606
Pubmed	An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors.	ADORA2A TLR2	1.81e-04	5	149	2	12875990
Pubmed	Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin.	MYO7A USH1C	1.81e-04	5	149	2	12588794
Pubmed	Usher I syndrome: unravelling the mechanisms that underlie the cohesion of the growing hair bundle in inner ear sensory cells.	MYO7A USH1C	1.81e-04	5	149	2	16219682
Pubmed	Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genes.	MYO7A USH1C	1.81e-04	5	149	2	22381527
Pubmed	Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F.	MYO7A USH1C	1.81e-04	5	149	2	11398101
Pubmed	Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.	MYO7A USH1C	1.81e-04	5	149	2	12485990
Pubmed	Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science.	FAS SCN10A	2.70e-04	6	149	2	21041692
Pubmed	RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport.	COPB1 COPG1	2.70e-04	6	149	2	10982407
Pubmed	Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex.	COPB1 COPG1	2.70e-04	6	149	2	8858162
Pubmed	The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex.	COPB1 COPG1	2.70e-04	6	149	2	14527956
Pubmed	Impact of the Usher syndrome on olfaction.	MYO7A USH1C	2.70e-04	6	149	2	26620972
Pubmed	The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate.	SLC1A4 NAGS	2.70e-04	6	149	2	21757002
Pubmed	Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney.	FAS TLR2	2.70e-04	6	149	2	29253517
Pubmed	Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system.	COPB1 COPG2	2.70e-04	6	149	2	11409905
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CIP2A ARFGEF3 TBC1D4 WIPI2 WDR62 PPP6R3	2.95e-04	209	149	6	36779422
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	IPO5 COPB1 CIP2A RTN4 NBEA MSH2 IPO4 TLN2 PPP6R3	3.13e-04	498	149	9	36634849
Pubmed	GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles.	COPB1 COPG1 COPG2	3.49e-04	32	149	3	34473204
Pubmed	Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm.	FBXL21P FBXL3	3.78e-04	7	149	2	23452855
Pubmed	FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes.	FBXL21P FBXL3	3.78e-04	7	149	2	23452856
Pubmed	The roles of USH1 proteins and PDZ domain-containing USH proteins in USH2 complex integrity in cochlear hair cells.	MYO7A USH1C	3.78e-04	7	149	2	28031293
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FJX1	3.78e-04	7	149	2	16059920
Pubmed	Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.	FAS TLR2	3.78e-04	7	149	2	11698470
Pubmed	Usher Syndrome Type I	MYO7A USH1C	3.78e-04	7	149	2	20301442
Pubmed	Reversible dissociation of coatomer: functional characterization of a beta/delta-coat protein subcomplex.	COPB1 COPG1	3.78e-04	7	149	2	9482852
Pubmed	The GSK-3β-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function.	FBXL21P FBXL3	3.78e-04	7	149	2	32937135
Pubmed	Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.	MYO7A USH1C	3.78e-04	7	149	2	21436032
Pubmed	Human and mouse proteases: a comparative genomic approach.	OVCH2 RHBDD2 PRSS42P PRSS48	4.17e-04	81	149	4	12838346
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	IPO5 COPB1 COPG1 CIP2A COPG2 MSH2 IPO4 TBC1D4 ZW10 PPP6R3	4.49e-04	638	149	10	33239621
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BOC PLEKHG4 DOCK8 ABCC10	5.00e-04	85	149	4	15449545
Pubmed	Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.	MYO7A USH1C	5.02e-04	8	149	2	19683999
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	MYO7A USH1C	5.02e-04	8	149	2	21165971
Pubmed	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	OVCH2 PKHD1	5.02e-04	8	149	2	19557197
Pubmed	Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.	STARD3 STARD3NL	5.02e-04	8	149	2	29858488
Pubmed	Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis.	RIPK3 FAS	5.02e-04	8	149	2	22864571
Pubmed	Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.	IPO5 IPO4	5.02e-04	8	149	2	27114554
Interaction	F2RL1 interactions	DYM CIP2A RTN4 PIGU SLC1A4 TSPAN3 ABCC8 ZW10 ATP12A	6.19e-06	182	143	9	int:F2RL1
Cytoband	3q13.2	BOC PLCXD2 SLC35A5	1.41e-04	31	149	3	3q13.2
Cytoband	20q11.22	PIGU MROH8 CEP250	2.40e-04	37	149	3	20q11.22
Cytoband	5q31	PCDHGC5 PCDHB9 KDM3B FBXL21P	5.57e-04	115	149	4	5q31
GeneFamily	Solute carriers	SLC7A13 FLVCR1 SLC35C2 SLCO1B1 SLC1A4 SLC26A8 SLC35B4 SLC35A2 SLC47A1 SLC4A4 SLC35A5	1.17e-05	395	100	11	752
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGN PIGP PIGU	2.03e-04	21	100	3	680
GeneFamily	UPF1 like RNA helicases	ZGRF1 DNA2	1.61e-03	11	100	2	1169
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	BOC SPEG OBSCN LINGO2 LRFN5	2.01e-03	161	100	5	593
GeneFamily	ATP binding cassette subfamily C	ABCC8 ABCC10	2.27e-03	13	100	2	807
ToppCell	IIH-CD8-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	PLEKHG4 ASAH2 FLVCR1 TTF1 TAS2R4 P3H1 WDR62	6.26e-07	146	149	7	7fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHST5 FLVCR1 PEX5L ARFGEF3 ABCC8 UNC13A GSG1	2.54e-06	180	149	7	6b1606238417490e0d9930870a7827419d1c3737
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLCXD2 USH1C ARFGEF3 AREL1 GALNT8 IFNE GSG1	3.04e-06	185	149	7	d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 SPEG SPTB OBSCN ABCC8 SCN10A SLC47A1	4.45e-06	196	149	7	a582130862bee76c0385156a333bfdfc75cf218b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 SPEG SPTB OBSCN ABCC8 SCN10A SLC47A1	4.45e-06	196	149	7	fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCell	COVID-19-lung-Mesothelial\|lung / Disease (COVID-19 only), tissue and cell type	BOC SPEG MUC16 PEX5L SLC4A4 ADGRD1	1.44e-05	156	149	6	e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CIP2A NDST4 KIAA1549L SCN10A PKHD1 ATP12A	1.78e-05	162	149	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	DCHS2 MUC16 NBEA ARFGEF3 ATP12A SLC4A4	2.67e-05	174	149	6	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	DCHS2 MUC16 NBEA ARFGEF3 ATP12A SLC4A4	3.13e-05	179	149	6	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 OBSCN ARFGEF3 PKHD1 TLN2 SLC4A4	3.65e-05	184	149	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 OBSCN ARFGEF3 PKHD1 TLN2 SLC4A4	3.65e-05	184	149	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 OBSCN ARFGEF3 PKHD1 TLN2 SLC4A4	3.65e-05	184	149	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHST5 MINAR2 EVI2A SLC35A2 STARD3 STARD3NL	4.36e-05	190	149	6	19faabab3f27579e380d2ac625876c6439933b44
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TMEM176A LINGO2 USH1C PEX5L ARFGEF3 UNC13A	4.49e-05	191	149	6	19832ddd559a353e1618fe853d79e3edfec6dcda
ToppCell	droplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 SPTB OBSCN TBC1D4 ABCC8 SLC47A1	4.49e-05	191	149	6	97fb4232417a39801e87725755fd16a57c250209
ToppCell	droplet-Heart-nan-3m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 SPTB OBSCN TBC1D4 ABCC8 SLC47A1	4.49e-05	191	149	6	64070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 SPTB OBSCN TBC1D4 ABCC8 SLC47A1	4.62e-05	192	149	6	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHST5 PEX5L ARFGEF3 ABCC8 UNC13A GSG1	4.62e-05	192	149	6	5692bd57093852d442400383850f416c497dcc7d
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TMEM176A LINGO2 USH1C PEX5L ARFGEF3 UNC13A	4.62e-05	192	149	6	4d3a1c267739b1479217144656986972fc86db43
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 SPTB OBSCN TBC1D4 ABCC8 SLC47A1	4.62e-05	192	149	6	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TMEM176A USH1C PEX5L ARFGEF3 ABCC8 UNC13A	4.76e-05	193	149	6	8603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHST5 DOCK8 TMEM176A USH1C GUCA2B GALNT8	5.48e-05	198	149	6	f95f38cc747fb3549a791288bf8d0518c049ac96
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-goblet\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHST5 DOCK8 TMEM176A USH1C GUCA2B GALNT8	5.48e-05	198	149	6	9c5d7852f03468394e726c444cac92a043fc6d0e
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HTR1D DSC2 ADORA2A SLC26A8 TLR2 TREM1	5.48e-05	198	149	6	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	mild-HLA-DR-_S100A+_Monocyte\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DSC2 HBEGF TMEM176A EVI2A TLR2 TREM1	5.80e-05	200	149	6	6dd89835a9f7bebb4849cff8eecb82caf6e1acbf
Disease	Usher syndrome, type 1B	MYO7A USH1C	2.33e-05	2	143	2	C2931206
Disease	Usher syndrome type 1 (is_implicated_in)	MYO7A USH1C	2.33e-05	2	143	2	DOID:0110826 (is_implicated_in)
Disease	USHER SYNDROME, TYPE I	MYO7A USH1C	2.33e-05	2	143	2	276900
Disease	Intellectual Disability	PIGP DOCK8 KDM3B NBEA CHD8 PIGU SLC1A4 FBXL3 SLC35A2 WDR62	6.85e-05	447	143	10	C3714756
Disease	Transitory neonatal diabetes mellitus	ZFP57 ABCC8	6.97e-05	3	143	2	cv:C0342273
Disease	Usher syndrome (implicated_via_orthology)	MYO7A USH1C	6.97e-05	3	143	2	DOID:0050439 (implicated_via_orthology)
Disease	keratoconjunctivitis (is_marker_for)	MUC16 TLR2	6.97e-05	3	143	2	DOID:9368 (is_marker_for)
Disease	bacterial pneumonia (implicated_via_orthology)	TLR2 TREM1	1.39e-04	4	143	2	DOID:874 (implicated_via_orthology)
Disease	Usher syndrome (is_implicated_in)	MYO7A USH1C	1.39e-04	4	143	2	DOID:0050439 (is_implicated_in)
Disease	Usher syndrome, type 1A	MYO7A USH1C	2.31e-04	5	143	2	C2931205
Disease	Diabetes Mellitus, Transient Neonatal, 1	ZFP57 ABCC8	2.31e-04	5	143	2	C1832386
Disease	USHER SYNDROME, TYPE IB (disorder)	MYO7A USH1C	2.31e-04	5	143	2	C1848638
Disease	USHER SYNDROME, TYPE IA, FORMERLY	MYO7A USH1C	2.31e-04	5	143	2	C1848639
Disease	USHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY	MYO7A USH1C	2.31e-04	5	143	2	C1848640
Disease	Usher syndrome type 1	MYO7A USH1C	2.31e-04	5	143	2	cv:C1568247
Disease	chorioamnionitis (is_marker_for)	FAS TREM1	3.45e-04	6	143	2	DOID:0050697 (is_marker_for)
Disease	Usher Syndrome, Type I	MYO7A USH1C	3.45e-04	6	143	2	C1568247
Disease	Cardiomyopathies	DSC2 FAS ADORA2A FKTN TLR2	4.39e-04	130	143	5	C0878544
Disease	Hereditary retinal dystrophy	MYO7A USH1C	4.82e-04	7	143	2	C0154860
Disease	Usher syndrome	MYO7A USH1C	4.82e-04	7	143	2	cv:C0271097
Disease	Neonatal diabetes mellitus	ZFP57 ABCC8	4.82e-04	7	143	2	cv:C0158981
Disease	carnitine measurement	SLC7A13 PEX5L SLC47A1 ABCC10	5.18e-04	76	143	4	EFO_0010469
Disease	Seizures	PIGP KDM3B NBEA PIGU ADORA2A FKTN	7.00e-04	218	143	6	C0036572
Disease	visual epilepsy (biomarker_via_orthology)	RTN4 MSH2 FAS ABCC8	9.78e-04	90	143	4	DOID:11832 (biomarker_via_orthology)
Disease	Short Stature, CTCAE	KDM3B FBXL3	1.02e-03	10	143	2	C2919142
Disease	Short stature	KDM3B FBXL3	1.02e-03	10	143	2	C0349588
Disease	dry eye syndrome (is_marker_for)	MUC16 TLR2	1.02e-03	10	143	2	DOID:10140 (is_marker_for)
Disease	2-aminobutyrate measurement	LINGO2 SLC1A4	1.02e-03	10	143	2	EFO_0020017
Disease	epilepsy (implicated_via_orthology)	SLC1A4 BDKRB1 SCN10A ATP12A UNC13A	1.22e-03	163	143	5	DOID:1826 (implicated_via_orthology)
Disease	QT interval	ARIH2OS PM20D1 AREL1 ABCC8 GALNT8 SCN10A STARD3 SLC4A4 PPP6R3	1.22e-03	534	143	9	EFO_0004682
Disease	guanosine diphosphate measurement	NBEA TBC1D4	1.25e-03	11	143	2	EFO_0010494
Disease	Chagas cardiomyopathy	TRAV4 SPTB SLCO1B1	1.28e-03	44	143	3	EFO_0005529
Disease	end stage renal disease (is_marker_for)	BDKRB1 IL20 TLR2	1.45e-03	46	143	3	DOID:783 (is_marker_for)
Disease	lung disease (implicated_via_orthology)	ADORA2A TLR2	1.76e-03	13	143	2	DOID:850 (implicated_via_orthology)
Disease	Cardiotoxicity	HBEGF TLR2	1.76e-03	13	143	2	C0876994
Disease	Colorectal Carcinoma	BOC RTN4 OBSCN MSH2 PEX5L HPS3 ABCC8 TLR2 PKHD1 ATP11C	2.29e-03	702	143	10	C0009402
Disease	spine bone mineral density	PIGN DCHS2 STARD3NL PPP6R3	2.73e-03	119	143	4	EFO_0007701
Disease	dermatomyositis (is_marker_for)	FAS TLR2	3.02e-03	17	143	2	DOID:10223 (is_marker_for)
Disease	Adenocarcinoma of lung (disorder)	IPO5 PIGN IPO4 TTF1 SLC4A4	3.37e-03	206	143	5	C0152013
Disease	susceptibility to vaginal yeast infection measurement	PEX5L PKHD1 TLN2	3.91e-03	65	143	3	EFO_0008412
Disease	Global developmental delay	PIGP KDM3B NBEA PIGU	4.07e-03	133	143	4	C0557874
Disease	hepatitis B (is_marker_for)	FAS TREM1	4.61e-03	21	143	2	DOID:2043 (is_marker_for)
Disease	Cardiomyopathies, Primary	FAS ADORA2A TLR2	4.62e-03	69	143	3	C0033141
Disease	Myocardial Diseases, Secondary	FAS ADORA2A TLR2	4.62e-03	69	143	3	C0036529

Protein segments in the cluster

Peptide	Gene	Start	Entry
NVLKSSRSLTISIVA	USH1C	276	Q9Y6N9
LKSTVDLLTSITFFR	UNC13A	966	Q9UPW8
SKSLVFSVLFAVTLR	TREM1	216	Q9NP99
ITSSKTVLVFLNLIF	TSPAN3	6	O60637
VARSSLSVALKFSQI	TTF1	646	Q15361
ASLFDAVSSLIRNKI	PRKAG1	136	P54619
SKTTALILTLVVAFL	BDKRB1	246	P46663
LSVVKVLSASEVAAL	CHD8	416	Q9HCK8
VLTQSSIFSLLAIAI	ADORA2A	86	P29274
EASAATAVKITLLSA	SERPINA3	371	P01011
LVATLVTFAVLSSVS	ADGRD1	581	Q6QNK2
LSKAFSGQRTLLSAI	GSG1	6	Q2KHT4
ALALLSAFSATQARK	APOA5	11	Q6Q788
IKSTVLSATTSLRVL	AASDH	301	Q4L235
ITTAAALSLNKATRS	ANO2	561	Q9NQ90
TTLRKAFLAQSTLLE	C3orf36	51	Q3SXR2
LLSSEKRSFTILLSN	DSC2	86	Q02487
ASLKLSALTQSLTRV	ARIH2OS	136	Q8N7S6
VSLATVIFVASQKAL	INTS7	491	Q9NVH2
LKLLTTLLAVVAAAS	P3H1	6	Q32P28
IVVAEATSSTALLKF	LRFN5	421	Q96NI6
NAIIRTTTALTIFKA	PM20D1	331	Q6GTS8
VLQGLLRSLFKSTSV	MUC16	13666	Q8WXI7
QLTATKVFTALALVR	ABCC10	531	Q5T3U5
LAFVDALLSSSVTLK	OR5H14	66	A6NHG9
LTLEVSTAKLTAFVA	KIAA0100	731	Q14667
VLIAALLFETSLTLK	MCMDC2	611	Q4G0Z9
VNRISLFLSTFTLAV	LMBR1	56	Q8WVP7
STITAIFSLAIALIT	LMBRD1	46	Q9NUN5
SAITVALLSLLFITS	ASAH2	21	Q9NR71
LLATVTVTLSLTAKR	ATP12A	351	P54707
KSLTRSSALLQASLV	MINAR2	21	P59773
VALATVSLLSLVTFT	PCDHGC5	696	Q9Y5F6
AVSNFLTALSLQRKS	PEX5L	561	Q8IYB4
FFVAASLATTLTKIA	COPB1	551	P53618
SLATTLTKIALRYVA	COPB1	556	P53618
FLFLSTVVLANKVSS	EVI2A	151	P22794
LLVSFILAALSLSTT	ENPP5	6	Q9UJA9
KRLLLLFADTAASAS	KDM3B	11	Q7LBC6
ANTFSLDLKTILVST	LINGO2	531	Q7L985
AALTSITASVKATRL	KIAA1549L	776	Q6ZVL6
ITAASTLLTELFSNK	NAGS	351	Q8N159
SLSSKTLFATVIQDL	NDST4	246	Q9H3R1
DAISFLSGKRLTLSL	NDST4	286	Q9H3R1
KITFLLQAIRNTTAA	IPO5	41	O00410
RAELFSLTIKSIITL	MROH8	176	Q9H579
VLRLVINLSSSVSTK	RICTOR	1616	Q6R327
ILTTIKGSAFLSAIF	PIGU	171	Q9H490
LKLAATSASARVVAA	NDUFA10	6	O95299
KNLSLSSTVFLSIDV	DCHS2	1486	Q6V1P9
SFTVSVAQKRFALIL	GPR149	301	Q86SP6
SSRVLISATLKNFQL	OBSCN	7506	Q5VST9
ALTFVLSSFLVTLIS	OR6V1	201	Q8N148
SLKTFRALLTLAAGA	FJX1	76	Q86VR8
LKTQLATLTSSLATV	GCC1	161	Q96CN9
KTRFLLSNLLIDTTS	BOC	276	Q9BWV1
TSAAAVSSKLLQARV	DOCK8	886	Q8NF50
ETALKNVFTALRSLI	DOCK9	1446	Q9BZ29
ALFLTLTTKLTNTNI	MT-CO2	41	P00403
AAQRIISLFSLLSKK	DYM	481	Q7RTS9
ISALTVVFVNSKSLS	FBXL3	161	Q9UKT7
TLAIAVNLLLVFSSK	GALNT8	16	Q9NY28
AKVVLTLSTQADRLF	ARFGEF3	1111	Q5TH69
ASQEASSIFKTLRTI	GUCA2B	81	Q16661
LALSLAQTKASVSSL	CEP250	2176	Q9BV73
AKTARLFNITSSALA	IFITM10	196	A6NMD0
ATVLSNAFVLTTILL	HTR1D	51	P28221
LLESSLKATRNFSIS	AREL1	471	O15033
LFSAALLATRSVITI	CRYM-AS1	36	A6NIL9
KATVAVLSFILSSAA	COMMD4	66	Q9H0A8
SNRSIATLAITTLLK	COPG2	336	Q9UBF2
FQTTVTAQILLKALT	EIF3K	61	Q9UBQ5
TSAVATLLFILTAIA	FLVCR1	281	Q9Y5Y0
KNVVLALLTLTSSAF	FKTN	6	O75072
STNIFTKRAIALITN	ARSB	211	P15848
LRKISSLANSFLTIK	IL20	106	Q9NYY1
SNRSIATLAITTLLK	COPG1	336	Q9Y678
KLTLAHRSFISLTNL	ERMARD	226	Q5T6L9
ITFEITFRSKNITIL	CTNS	56	O60931
SVVLKLFLAAVLSAL	HBEGF	6	Q99075
AKKTSALTLRSSFLL	CELSR3	2716	Q9NYQ7
VSNVTEAKLIVFLTS	DNA2	911	P51530
TVRLGVSKLLLSFAS	GML	136	Q99445
VSKLLLSFASIIVSN	GML	141	Q99445
VSLSLAQLSATIFRK	IPO4	96	Q8TEX9
AVSSLSAVIKFLELL	MSH2	266	P43246
TSLTLIVFLFHRLSK	PIGP	6	P57054
TSTIRALIKNFSIAS	FAM8A1	366	Q9UBU6
LVLLASTTIFSLDLK	IFNE	11	Q86WN2
SAVSKLLLSASEFQV	PRR14L	1961	Q5THK1
VVALASVSSLFLLSV	PCDHB9	691	Q9Y5E1
SVSSLFLLSVLLFVA	PCDHB9	696	Q9Y5E1
SYVLIISTVLKIASA	OR10J6P	216	Q8NGY7
FVSALTVVFINSKSL	FBXL21P	166	Q9UKT6
TSSLILTLNTVFVLA	RNF139	181	Q8WU17
FLLLSLTVFSIVSVT	RTN4	1026	Q9NQC3
SLTVTLVVTLRKFVS	SLC35B4	266	Q969S0
LTLAAFSTAIAALKL	TMEM176A	121	Q96HP8
FSSILVTLTKAAVAL	HPS3	671	Q969F9
LTTLCLVKTFTAAVR	LMBR1L	446	Q6UX01
ARDTFVLQASSLAIK	PLEKHG4	1001	Q58EX7
SKEAQLISFLALLSS	SAMD9L	916	Q8IVG5
KIILQAFSLSLVSSF	SLC26A8	356	Q96RN1
AILASLTVISVKAVS	NIPAL2	216	Q9H841
SILIGSNSLRLKFVS	OVCH2	391	Q7RTZ1
TLLAFLVELLKSSVA	NBEA	526	Q8NFP9
LEKAIATTALIFRNS	SNTN	56	A6NMZ2
FKALRIVVTLLATFS	TMEM69	211	Q5SWH9
RLFSSSLVAIVSLKA	WIPI2	81	Q9Y4P8
KSTIILAASLSSVAS	PKHD1	3856	P08F94
LAALSLSFIAKTLGA	SLCO1B1	31	Q9Y6L6
QARKSSTVSLLITVL	SLC47A1	331	Q96FL8
SSAFLIVKVILSELL	STARD3	131	Q14849
LKGFATSLSIVLSTV	SLC35A2	296	P78381
FLLSSVVRSTVKALV	ABCC8	591	Q09428
SLTVVVFALSILSSL	CIP2A	201	Q8TCG1
RFSSKTVTVLLLAQT	CHST5	26	Q9GZS9
LVFTVTLKLALDTRF	ATP11C	1006	Q8NB49
DLSTKLSSNALVFRI	UFSP2	41	Q9NUQ7
SSIKRVLAITTVLSL	TPRA1	146	Q86W33
SFTLLCTSLTVFIKL	TMEM212	156	A6NML5
CTSLTVFIKLSARLI	TMEM212	161	A6NML5
SETFKNLTSVARIFL	ZFP57	46	Q9NU63
SKLFILLTLATSSLL	NPVF	6	Q9HCQ7
NTSQSATLFLRKVLS	SPEG	3186	Q15772
AAVSTVKDFLSQLRS	RIPK3	296	Q9Y572
TLFLSIVALTAGTKT	SLC35A5	156	Q9BS91
VLTSVARLSSKSVNA	FAS	11	P25445
NTTSVRKLILFLETT	PLCXD2	236	Q0VAA5
TGLIFLTLTKTIANT	ST20	61	Q9HBF5
LSASALAVALAFIIK	SLC1A4	126	P43007
IASLIFSAILKSLQS	SCN10A	1551	Q9Y5Y9
AIIFLSFEAVSSLSK	RHBDD2	111	Q6NTF9
IALTTAVTSAFLLAK	STARD3NL	126	O95772
KFSTVTTIRNDLALL	PRSS42P	156	Q7Z5A4
TKSSAVLFILIFSLI	SLC35C2	116	Q9NQQ7
IASSVLKVSILSFIS	SLC7A13	161	Q8TCU3
TITVLNSRKFANSLT	SPTB	321	P11277
LTTQLSSKSLFLIVL	PIGN	851	O95427
IFKVALSLLSSQETL	TBC1D4	1116	O60343
ALLKLSSQVTFTSAI	PRSS48	116	Q7RTY5
RLSISTQFLSSLQKA	WDR62	1091	O43379
TNTLSKAAFLLTVLS	ZSWIM8	831	A7E2V4
AEATFTLKLIQSLIA	ZGRF1	1936	Q86YA3
ILEAAKSIAAATSAL	TLN2	2346	Q9Y4G6
TTARKLISDFAIILS	SLC4A4	721	Q9Y6R1
TLLTDSSIRLFANKS	XPNPEP2	266	O43895
SAEKVSQLLSFATTL	VWA8	286	A3KMH1
ASLTLSREAQKFALA	TMEM177	141	Q53S58
ETSLFSHLTKLQILR	TLR2	141	O60603
LLVLKISRNAITTFS	TLR2	501	O60603
ASFFSKVLSILISRK	PPP6R3	121	Q5H9R7
RVIVFLTLSTLSLAK	TRAV4	6	A0A0B4J268
TSSALAFLKSRSKLL	ZFYVE26	1301	Q68DK2
LDLSSTFVSLALRKV	TTC31	231	Q49AM3
SLVVSLVLSSSLQFI	TAS2R4	176	Q9NYW5
AFSSSEVKALIRALF	ZW10	751	O43264
IATRLLLKSSEGFSL	MYO7A	1931	Q13402