Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ATMIN ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZFP14 ZNF621 ZNF75CP ZNF112 ZNF236 CREB3L4 ZNF416 PASD1 OVOL2 HOXA3 MTF1 ZSCAN30 KLF5 TP63 ZNF84 ZNF841 CDC5L ZNF876P ZNF471 NFAT5 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	2.07e-08	1412	168	34	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF135 ZNF143 ZNF354A ZNF584 ZNF570 ZNF780B ZNF629 ZFP14 ZNF621 ZNF75CP ZNF112 ZNF236 CREB3L4 ZNF416 PASD1 OVOL2 HOXA3 MTF1 ZSCAN30 KLF5 TP63 ZNF84 ZNF841 ZNF876P ZNF471 NFAT5 ZNF415 TOP1 ZFP82 ZNF345 ZNF304	4.52e-08	1244	168	31	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZFP14 ZNF621 ZNF75CP ZNF112 ZNF236 CREB3L4 ZNF416 PASD1 OVOL2 HOXA3 MTF1 ZSCAN30 KLF5 TP63 ZNF84 ZNF841 CDC5L ZNF876P ZNF471 NFAT5 ZNF415 TOP1 ZFP82 ZNF345 ZNF554 ZNF304	4.59e-08	1459	168	34	GO:0000977
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF135 ZNF143 ZNF354A ZNF584 ZNF570 ZNF780B ZNF629 ZFP14 ZNF621 ZNF75CP ZNF112 ZNF236 CREB3L4 ZNF416 PASD1 OVOL2 HOXA3 MTF1 ZSCAN30 KLF5 TP63 ZNF84 ZNF841 ZNF876P ZNF471 NFAT5 ZNF415 TOP1 ZFP82 ZNF345 ZNF304	7.33e-08	1271	168	31	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ATMIN ZNF143 ZNF780B ZNF629 ZNF112 CREB3L4 OVOL2 BRCA1 MTF1 KLF5 TP63 ZNF841 CDC5L NFAT5 ZNF345	9.10e-05	566	168	15	GO:0001216
GeneOntologyMolecularFunction	axon guidance receptor activity	EPHB2 SEMA5A HMCN2	1.57e-04	13	168	3	GO:0008046
GeneOntologyMolecularFunction	chondroitin sulfate proteoglycan binding	SEMA5A PTPRF	2.10e-04	3	168	2	GO:0035373
GeneOntologyMolecularFunction	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity	PCMTD1 PCMTD2	2.10e-04	3	168	2	GO:0004719
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ATMIN ZNF143 ZNF780B ZNF629 ZNF112 CREB3L4 OVOL2 MTF1 KLF5 TP63 ZNF841 CDC5L NFAT5 ZNF345	2.85e-04	560	168	14	GO:0001228
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	GANC SI	6.92e-04	5	168	2	GO:0004558
GeneOntologyCellularComponent	anchoring junction	MAGI1 FLNC DCHS2 NRAP ANK2 LIMS4 CAT ITGA2B TEC ITGA5 MFRP LIMS3 CLCA2 AVIL CSPG4 FLRT2 VSIG10L2 CDH11 TNS3 EPHA5	1.26e-04	976	169	20	GO:0070161
Domain	zf-C2H2	ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 ZNF106 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	9.53e-11	693	166	27	PF00096
Domain	ZINC_FINGER_C2H2_2	ATMIN ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 ZNF106 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	2.32e-10	775	166	28	PS50157
Domain	ZINC_FINGER_C2H2_1	ATMIN ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 ZNF106 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	2.46e-10	777	166	28	PS00028
Domain	-	ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	3.21e-10	679	166	26	3.30.160.60
Domain	Znf_C2H2-like	ATMIN ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 ZNF106 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	4.25e-10	796	166	28	IPR015880
Domain	Znf_C2H2/integrase_DNA-bd	ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	5.12e-10	694	166	26	IPR013087
Domain	Znf_C2H2	ATMIN ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 ZNF106 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	5.48e-10	805	166	28	IPR007087
Domain	ZnF_C2H2	ATMIN ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 ZNF106 MTF1 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	5.96e-10	808	166	28	SM00355
Domain	zf-C2H2_6	ZNF135 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZFP14 ZNF621 ZNF236 ZNF416 ZSCAN30 ZNF84 ZNF841 ZFP82 ZNF345 ZNF554	2.16e-08	314	166	16	PF13912
Domain	KRAB	ZNF135 ZNF354A ZNF584 ZNF570 ZNF780B ZFP14 ZNF621 ZNF112 ZNF416 ZNF84 ZNF471 ZFP82 ZNF554 ZNF304	3.98e-06	358	166	14	PS50805
Domain	KRAB	ZNF135 ZNF354A ZNF584 ZNF570 ZNF780B ZFP14 ZNF621 ZNF112 ZNF416 ZNF84 ZNF471 ZFP82 ZNF554 ZNF304	3.98e-06	358	166	14	PF01352
Domain	KRAB	ZNF135 ZNF354A ZNF584 ZNF570 ZNF780B ZFP14 ZNF621 ZNF112 ZNF416 ZNF84 ZNF471 ZFP82 ZNF554 ZNF304	5.64e-06	369	166	14	SM00349
Domain	KRAB	ZNF135 ZNF354A ZNF584 ZNF570 ZNF780B ZFP14 ZNF621 ZNF112 ZNF416 ZNF84 ZNF471 ZFP82 ZNF554 ZNF304	5.82e-06	370	166	14	IPR001909
Domain	JIP_LZII	SPAG9 MAPK8IP3	7.85e-05	2	166	2	IPR032486
Domain	JIP_LZII	SPAG9 MAPK8IP3	7.85e-05	2	166	2	PF16471
Domain	PCMT	PCMTD1 PCMTD2	2.34e-04	3	166	2	IPR000682
Domain	PCMT	PCMTD1 PCMTD2	2.34e-04	3	166	2	PS01279
Domain	FN3	EPHB2 FLNC LRRN1 ELFN2 PTPRF FLRT2 IL6ST EPHA5	2.54e-04	185	166	8	SM00060
Domain	DOMON	DBH FRRS1	4.66e-04	4	166	2	PS50836
Domain	Arrestin_N	ARR3 ARRB1	4.66e-04	4	166	2	IPR014753
Domain	JNK/Rab-associated_protein-1_N	SPAG9 MAPK8IP3	4.66e-04	4	166	2	IPR019143
Domain	DOMON_domain	DBH FRRS1	4.66e-04	4	166	2	IPR005018
Domain	Arrestin_CS	ARR3 ARRB1	4.66e-04	4	166	2	IPR017864
Domain	ARRESTINS	ARR3 ARRB1	4.66e-04	4	166	2	PS00295
Domain	DoH	DBH FRRS1	4.66e-04	4	166	2	SM00664
Domain	Arrestin	ARR3 ARRB1	4.66e-04	4	166	2	IPR000698
Domain	Jnk-SapK_ap_N	SPAG9 MAPK8IP3	4.66e-04	4	166	2	PF09744
Domain	-	ARR3 ARRB1	4.66e-04	4	166	2	2.60.40.840
Domain	DOMON	DBH FRRS1	4.66e-04	4	166	2	PF03351
Domain	FN3_dom	EPHB2 FLNC LRRN1 ELFN2 PTPRF FLRT2 IL6ST EPHA5	5.73e-04	209	166	8	IPR003961
Domain	RH2	SPAG9 MAPK8IP3	7.72e-04	5	166	2	PS51777
Domain	RH1	SPAG9 MAPK8IP3	7.72e-04	5	166	2	PS51776
Domain	FG_GAP	CRTAC1 ITGA2B ITGA5	9.38e-04	22	166	3	PS51470
Domain	Glyco_hydro_31_AS	GANC SI	1.15e-03	6	166	2	IPR030458
Domain	FG-GAP	CRTAC1 ITGA2B ITGA5	1.22e-03	24	166	3	PF01839
Domain	FG-GAP	CRTAC1 ITGA2B ITGA5	1.22e-03	24	166	3	IPR013517
Domain	Glyco_hydro_31	GANC SI	1.60e-03	7	166	2	IPR000322
Domain	Glyco_hydro_31	GANC SI	1.60e-03	7	166	2	PF01055
Domain	-	ARR3 ARRB1	1.60e-03	7	166	2	2.60.40.640
Domain	GLYCOSYL_HYDROL_F31_1	GANC SI	1.60e-03	7	166	2	PS00129
Domain	AT_hook	FAM171B KMT2A DOT1L	1.72e-03	27	166	3	SM00384
Domain	AT_hook_DNA-bd_motif	FAM171B KMT2A DOT1L	1.72e-03	27	166	3	IPR017956
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DCHS2 ANK2 ZNF584 TNPO2 RAPGEF4 CRTAC1 NCAPH2 TMED4 MAPK8IP3 THAP4 ARRB1 FBXO7 RNF38 MACF1 ENPP5 PCMTD2 ZNF84 ZNF841 TOP1 RSBN1L MED13 ALPL	3.92e-07	1285	171	22	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CTTNBP2 LRRN1 MARK1 ZNF629 ZNF407 SPAG9 VARS2 ELFN2 TNRC18 MACF1 FLRT2 CDC5L PRMT7	1.12e-06	493	171	13	15368895
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNC ANK2 PCDHGB1 DTNB CAT ANKLE2 TNRC18 ARRB1 TBC1D31 BRCA1 AVIL CSPG4 KMT2A CC2D2A SMARCC2 MACF1 PABPC1L ZNF84 POFUT1 TOP1 MED13	9.11e-06	1442	171	21	35575683
Pubmed	Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis.	ATMIN ATR TP63	9.60e-06	9	171	3	20975950
Pubmed	Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.	ACTL6A KMT2A SMARCC2	1.37e-05	10	171	3	12665591
Pubmed	Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.	ATR ACTL6A BRCA1 SMARCC2	1.40e-05	30	171	4	31043422
Pubmed	Competition is a driving force in topographic mapping.	EPHB2 TENM3 EPHA5	1.87e-05	11	171	3	22065784
Pubmed	Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.	RAPGEF4 PLCE1	2.40e-05	2	171	2	21478675
Pubmed	Distinct Responses to Menin Inhibition and Synergy with DOT1L Inhibition in KMT2A-Rearranged Acute Lymphoblastic and Myeloid Leukemia.	KMT2A DOT1L	2.40e-05	2	171	2	38892207
Pubmed	TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2.	CLCA2 TP63	2.40e-05	2	171	2	38528613
Pubmed	MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.	KMT2A DOT1L	2.40e-05	2	171	2	21741597
Pubmed	Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons.	SPAG9 MAPK8IP3	2.40e-05	2	171	2	33788575
Pubmed	DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy.	KMT2A DOT1L	2.40e-05	2	171	2	24858818
Pubmed	Validation of NG2 antigen in identifying BP-ALL patients with MLL rearrangements using qualitative and quantitative flow cytometry: a prospective study.	CSPG4 KMT2A	2.40e-05	2	171	2	17851550
Pubmed	The role of DOT1L in the maintenance of leukemia gene expression.	KMT2A DOT1L	2.40e-05	2	171	2	27151433
Pubmed	Preconditioning-induced protection of photoreceptors requires activation of the signal-transducing receptor gp130 in photoreceptors.	RPE65 IL6ST	2.40e-05	2	171	2	19948961
Pubmed	Structural characterization of the RH1-LZI tandem of JIP3/4 highlights RH1 domains as a cytoskeletal motor-binding motif.	SPAG9 MAPK8IP3	2.40e-05	2	171	2	31690808
Pubmed	ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.	ATR TOP1	2.40e-05	2	171	2	25269479
Pubmed	An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.	ATR BRCA1	2.40e-05	2	171	2	16738325
Pubmed	Germline mutations in NF1 and BRCA1 in a family with neurofibromatosis type 1 and early-onset breast cancer.	NF1 BRCA1	2.40e-05	2	171	2	23624750
Pubmed	ΔNp63α induces quiescence and downregulates the BRCA1 pathway in estrogen receptor-positive luminal breast cancer cell line MCF7 but not in other breast cancer cell lines.	BRCA1 TP63	2.40e-05	2	171	2	26704768
Pubmed	β-Cell-intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion.	RAPGEF4 ARRB1	2.40e-05	2	171	2	31184597
Pubmed	Intact calcium signaling in adrenergic-deficient embryonic mouse hearts.	CACNA2D1 DBH	2.40e-05	2	171	2	29288665
Pubmed	The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D.	NF1 BRCA1	2.40e-05	2	171	2	8566965
Pubmed	Identification of residues of functional importance within the central turn motifs present in the cytoplasmic tails of integrin alphaIIb and alphaV subunits.	ITGA2B ITGA5	2.40e-05	2	171	2	18328539
Pubmed	The molecular mechanics of mixed lineage leukemia.	KMT2A DOT1L	2.40e-05	2	171	2	26923329
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FLNC CTTNBP2 NRAP ANK2 ZNF407 TAB2 PRKD3 MACF1 MED13 IL6ST PLCE1	3.86e-05	497	171	11	23414517
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	ANK2 TNPO2 SPAG9 FAM171B ELFN2 MAPK8IP3 MACF1	5.76e-05	197	171	7	36604605
Pubmed	Development of serous ovarian cancer is associated with the expression of homologous recombination pathway proteins.	ATR BRCA1	7.19e-05	3	171	2	24752797
Pubmed	Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.	ATR KMT2A	7.19e-05	3	171	2	27625305
Pubmed	A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.	ATR BRCA1	7.19e-05	3	171	2	12773400
Pubmed	Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint.	ATR CDC5L	7.19e-05	3	171	2	19633697
Pubmed	Klf5 acetylation regulates luminal differentiation of basal progenitors in prostate development and regeneration.	KLF5 TP63	7.19e-05	3	171	2	32081850
Pubmed	Identification of ocular regulatory functions of core histone variant H3.2.	EPHB2 EPHA5	7.19e-05	3	171	2	36529279
Pubmed	Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.	ATR BRCA1	7.19e-05	3	171	2	11114888
Pubmed	Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.	KMT2A DOT1L	7.19e-05	3	171	2	28394257
Pubmed	The scaffold protein JIP3 functions as a downstream effector of the small GTPase ARF6 to regulate neurite morphogenesis of cortical neurons.	SPAG9 MAPK8IP3	7.19e-05	3	171	2	20493856
Pubmed	Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond.	KMT2A DOT1L	7.19e-05	3	171	2	26118503
Pubmed	BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.	ATR BRCA1	7.19e-05	3	171	2	15589157
Pubmed	Calcineurin Inhibition Causes α2δ-1-Mediated Tonic Activation of Synaptic NMDA Receptors and Pain Hypersensitivity.	CACNA2D1 AVIL	7.19e-05	3	171	2	32269108
Pubmed	ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.	ACTL6A TP63	7.19e-05	3	171	2	28041841
Pubmed	Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.	BRCA1 TOP1	7.19e-05	3	171	2	18588899
Pubmed	JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.	SPAG9 MAPK8IP3	7.19e-05	3	171	2	25571974
Pubmed	Coupling of Homologous Recombination and the Checkpoint by ATR.	ATR BRCA1	7.19e-05	3	171	2	28089683
Pubmed	Neurofibromatosis with male breast cancer--risk factor or co-incidence? Report of two rare cases.	NF1 BRCA1	7.19e-05	3	171	2	25267367
Pubmed	Increased thrombospondin-4 after nerve injury mediates disruption of intracellular calcium signaling in primary sensory neurons.	CACNA2D1 AVIL	7.19e-05	3	171	2	28232180
Pubmed	TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines.	KLF5 TP63	7.19e-05	3	171	2	32619460
Pubmed	Cannabinoid 1 (CB1 ) receptor arrestin subtype-selectivity and phosphorylation dependence.	ARR3 ARRB1	7.19e-05	3	171	2	36250246
Pubmed	Identification of risk loci for Crohn's disease phenotypes using a genome-wide association study.	MAGI1 CLCA2	7.19e-05	3	171	2	25557950
Pubmed	Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer.	KLF5 TP63	7.19e-05	3	171	2	34272396
Pubmed	Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk.	DTNB DNAH11	7.19e-05	3	171	2	22120009
Pubmed	The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons.	RAPGEF4 PLCE1	7.19e-05	3	171	2	28209735
Pubmed	ATR, BRCA1 and gammaH2AX localize to unsynapsed chromosomes at the pachytene stage in human oocytes.	ATR BRCA1	7.19e-05	3	171	2	19146767
Pubmed	ATR/ATM-Mediated Phosphorylation of BRCA1 T1394 Promotes Homologous Recombinational Repair and G2-M Checkpoint Maintenance.	ATR BRCA1	7.19e-05	3	171	2	34301763
Pubmed	Identification of receptor binding-induced conformational changes in non-visual arrestins.	ARR3 ARRB1	7.19e-05	3	171	2	24867953
Pubmed	Roles for GP IIb/IIIa and αvβ3 integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction.	ITGA2B ITGA5	7.19e-05	3	171	2	24176823
Pubmed	Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways.	ATR BRCA1	7.19e-05	3	171	2	24672057
Pubmed	Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.	KMT2A DOT1L	7.19e-05	3	171	2	23361907
Pubmed	DOT1L-mediated RAP80 methylation promotes BRCA1 recruitment to elicit DNA repair.	BRCA1 DOT1L	7.19e-05	3	171	2	39172790
Pubmed	Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice.	PIEZO2 AVIL	7.19e-05	3	171	2	30726728
Pubmed	Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.	KMT2A DOT1L	7.19e-05	3	171	2	21398221
Pubmed	ASCIZ regulates lesion-specific Rad51 focus formation and apoptosis after methylating DNA damage.	ATMIN ATR	7.19e-05	3	171	2	15933716
Pubmed	Divalent cations differentially regulate integrin alphaIIb cytoplasmic tail binding to beta3 and to calcium- and integrin-binding protein.	ITGA2B ITGA5	7.19e-05	3	171	2	10358085
Pubmed	Central Mechanisms Mediating Thrombospondin-4-induced Pain States.	CACNA2D1 AVIL	7.19e-05	3	171	2	27129212
Pubmed	BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers.	BRCA1 TP63	7.19e-05	3	171	2	23863842
Pubmed	Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke.	RAPGEF4 PLCE1	7.19e-05	3	171	2	25103224
Pubmed	Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model.	NF1 BRCA1	7.19e-05	3	171	2	37207276
Pubmed	Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies.	ATR BRCA1	7.19e-05	3	171	2	11278964
Pubmed	JSAP1 and JLP are required for ARF6 localization to the midbody in cytokinesis.	SPAG9 MAPK8IP3	7.19e-05	3	171	2	25130574
Pubmed	IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells.	SPARC ITGA5	7.19e-05	3	171	2	18583538
Pubmed	A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.	KMT2A DOT1L	7.19e-05	3	171	2	31527241
Pubmed	Mouse cones require an arrestin for normal inactivation of phototransduction.	ARR3 ARRB1	7.19e-05	3	171	2	18701071
Pubmed	α2δ-1 Upregulation in Primary Sensory Neurons Promotes NMDA Receptor-Mediated Glutamatergic Input in Resiniferatoxin-Induced Neuropathy.	CACNA2D1 AVIL	7.19e-05	3	171	2	34252037
Pubmed	Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice.	SPAG9 MAPK8IP3	7.19e-05	3	171	2	26320416
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CASP8AP2 NEMP1 TMEM201 RAE1 ATR ZNF629 NCAPH2 ACTL6A THAP4 ZNF106 BRCA1 ZSCAN30 KLF5 ANKRD11 KMT2A CDC5L TOP1 SLC27A2	7.44e-05	1294	171	18	30804502
Pubmed	The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.	DTNB ANKRD11 DNAH11	7.55e-05	17	171	3	23502783
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ABCA13 ITGA5 NF1 HMCN2 MACF1 DNAH9 TOP1 TNS3 ALPL	8.07e-05	361	171	9	26167880
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB2 NEMP1 CACNA2D1 TMEM201 ATR NCAPH2 ITGA5 MRPS22 TMED4 IGSF10 NF1 PTPRF TENM3 CSPG4 SEL1L3 POFUT1 IL6ST	9.65e-05	1201	171	17	35696571
Pubmed	C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway.	DBH PIEZO2 AVIL	1.07e-04	19	171	3	38915692
Pubmed	Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.	ATMIN PJA2 FLRT2 CDC5L	1.27e-04	52	171	4	9455477
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CASP8AP2 NEMP1 TAB2 SPAG9 MACF1 POFUT1 CDC5L	1.32e-04	225	171	7	12168954
Pubmed	Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.	RAPGEF4 PLCE1	1.43e-04	4	171	2	21041529
Pubmed	NuMorph: Tools for cortical cellular phenotyping in tissue-cleared whole-brain images.	NF1 TOP1	1.43e-04	4	171	2	34644582
Pubmed	Interaction between BRCA1/BRCA2 and ATM/ATR associate with breast cancer susceptibility in a Chinese Han population.	ATR BRCA1	1.43e-04	4	171	2	20513533
Pubmed	ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis.	ATR BRCA1	1.43e-04	4	171	2	15650754
Pubmed	Ataxia telangiectasia-related protein is involved in the phosphorylation of BRCA1 following deoxyribonucleic acid damage.	ATR BRCA1	1.43e-04	4	171	2	11016625
Pubmed	ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.	BRCA1 TP63	1.43e-04	4	171	2	23243027
Pubmed	Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix.	CAT SLC27A2	1.43e-04	4	171	2	16781659
Pubmed	Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development.	ATMIN DNAH11	1.43e-04	4	171	2	19235720
Pubmed	MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.	KMT2A DOT1L	1.43e-04	4	171	2	26927674
Pubmed	RNF186/EPHB2 Axis Is Essential in Regulating TNF Signaling for Colorectal Tumorigenesis in Colorectal Epithelial Cells.	EPHB2 TAB2	1.43e-04	4	171	2	36130827
Pubmed	Identification of a novel binding site for platelet integrins alpha IIb beta 3 (GPIIbIIIa) and alpha 5 beta 1 in the gamma C-domain of fibrinogen.	ITGA2B ITGA5	1.43e-04	4	171	2	12799374
Pubmed	The DeltaNp63 proteins are key allies of BRCA1 in the prevention of basal-like breast cancer.	BRCA1 TP63	1.43e-04	4	171	2	21363924
Pubmed	Methylation analysis of BRCA1, RASSF1, GSTP1 and EPHB2 promoters in prostate biopsies according to different degrees of malignancy.	EPHB2 BRCA1	1.43e-04	4	171	2	19454503
Pubmed	Involvement of integrins alpha(3)beta(1) and alpha(5)beta(1) and glycoprotein IIb in megakaryocyte-induced osteoblast proliferation.	ITGA2B ITGA5	1.43e-04	4	171	2	20052668
Pubmed	cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.	EPHB2 EPHA5	1.43e-04	4	171	2	7898931
Pubmed	Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.	DNAH9 DNAH11	1.43e-04	4	171	2	36140829
Pubmed	Calcium Integrin Binding Protein Associates with Integrins αVβ3 and αIIbβ3 Independent of β3 Activation Motifs.	ITGA2B ITGA5	1.43e-04	4	171	2	24163826
Pubmed	DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.	KMT2A DOT1L	1.43e-04	4	171	2	21521783
Pubmed	Phosphorylation of ATR-interacting protein on Ser239 mediates an interaction with breast-ovarian cancer susceptibility 1 and checkpoint function.	ATR BRCA1	1.43e-04	4	171	2	17616665
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF135 ZNF584 ZNF570 ZNF780B ZFP14 ZNF112 ZNF416 DHDH CEP89 NFKBIB CEACAM16 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF304	2.63e-06	1192	171	17	chr19q13
Cytoband	19q13.12	ZNF570 ZFP14 ZFP82 ZNF345	1.57e-04	72	171	4	19q13.12
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ATMIN ZNF135 ZNF143 ZNF354A ZNF391 ZNF584 ZNF570 ZNF780B ZNF629 ZNF407 ZFP14 ZNF621 ZNF112 ZNF236 ZNF416 OVOL2 ZNF106 ZSCAN30 KLF5 ZNF84 ZNF841 ZNF471 ZNF415 ZFP82 ZNF345 ZNF554 ZNF304	7.66e-14	718	117	27	28
GeneFamily	Classical arrestins	ARR3 ARRB1	2.47e-04	4	117	2	1312
GeneFamily	LIM zinc finger domain containing\|LIM domain containing	LIMS4 LIMS3	2.47e-04	4	117	2	1163
GeneFamily	Fibronectin type III domain containing	EPHB2 ELFN2 PTPRF FLRT2 IL6ST EPHA5	6.09e-04	160	117	6	555
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ZNF407 HMGCS1 NF1 ANKRD11 KMT2A MACF1 NFAT5 MED13 IL6ST	4.98e-08	188	171	9	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 FLNC SEMA5A PTPRF TP63 FLRT2 CDH11 TNS3 PLCE1	5.97e-08	192	171	9	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL SLC27A2	6.81e-08	195	171	9	2a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 CREB3L4 ADAM28 LIMS3 CLCA2 SEL1L3 ALPL SLC27A2	2.80e-07	167	171	8	31633899aae852873a4887e72c621474b0a51a33
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL SLC27A2	3.66e-07	173	171	8	3aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL SLC27A2	3.66e-07	173	171	8	e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TDRKH RAPGEF4 PIEZO2 PCMTD2 POFUT1 TOP1 CDH11 TNS3	4.55e-07	178	171	8	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	IPF-Endothelial-Lymphatic\|IPF / Disease state, Lineage and Cell class	MAGI1 FLNC RAPGEF4 CRTAC1 FAM171B LIMS3 PIEZO2 FLRT2	8.06e-07	192	171	8	2496edd8f3a41146d418879de9ee2ccc7857431f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPHB2 SPARC ANK2 SEMA5A IGSF10 PIEZO2 HMCN2 FLRT2	8.06e-07	192	171	8	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPHB2 SPARC ANK2 SEMA5A IGSF10 PIEZO2 HMCN2 FLRT2	8.72e-07	194	171	8	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL SLC27A2	9.06e-07	195	171	8	576142b4e75457c0973051bccc4163bd624496af
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL SLC27A2	9.06e-07	195	171	8	8f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|COVID-19 / Condition, Lineage and Cell class	LRRN1 ABCA13 STEAP4 ADAM28 CLCA2 KLF5 TP63 ALPL	9.42e-07	196	171	8	dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC SEMA5A PTPRF TP63 FLRT2 CDH11 TNS3 PLCE1	9.42e-07	196	171	8	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANK2 SEMA5A DNAI3 IGSF10 TENM3 MACF1 CDH11 IL6ST	1.06e-06	199	171	8	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	COVID-19-COVID-19_Mild-Others-HSPC\|COVID-19_Mild / Disease, condition lineage and cell class	ZNF135 PRSS57 CREB3L4 TFR2 HOXA3 IGSF10 TEC SLC27A2	1.06e-06	199	171	8	0230103c37ae3aff58240739b89f2c36b1e39a69
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC CTTNBP2 ZNF629 MSANTD2 SEMA5A CSPG4 ZNF304	2.78e-06	159	171	7	7cda111bb98f1241989e49d490bdf51a712ea589
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|bone_marrow / Manually curated celltypes from each tissue	PRSS57 TEX15 ITGA2B LIMS3 TFR2 PIEZO2 HMCN2	3.70e-06	166	171	7	a853005a5587d42daecdf2e23a93109919021a4f
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRAP LRRN1 ZNF391 STEAP4 ZNF416 PTPRF CLCA2	5.04e-06	174	171	7	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 CTTNBP2 ABCA13 SEL1L3 NFAT5 SLC27A2 DNAH11	5.85e-06	178	171	7	c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DCHS2 CTTNBP2 CRTAC1 TENM3 TP63 CDH11 PLCE1	6.07e-06	179	171	7	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA2D1 SPARC MARK1 STEAP4 SEMA5A CSPG4 PLCE1	6.53e-06	181	171	7	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAGI1 LIMS4 PIEZO2 TENM3 FLRT2 NFAT5 IL6ST	6.77e-06	182	171	7	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 SPARC MARK1 TENM3 KLF5 CDH11 PLCE1	7.53e-06	185	171	7	872720275789d249c9859de825a923803d458875
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ZNF629 F2RL2 GDPD5 PCMTD2 POFUT1 CDH11 TNS3	8.36e-06	188	171	7	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	cellseq2-Epithelial-Epithelial_Airway\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA13 DNAI3 CLCA2 TP63 DNAH9 SLC27A2 DNAH11	8.96e-06	190	171	7	17829f4de31b3d9e4d71ba4817d18842aa699773
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 MAGI1 CTTNBP2 ABCA13 SEL1L3 NFAT5 TNS3	9.27e-06	191	171	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 SEMA5A DNAI3 IGSF10 PIEZO2 TENM3 CDH11	9.59e-06	192	171	7	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	COVID-19-lung-Secretory\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRRN1 ADAM28 PTPRF CLCA2 KLF5 TP63 SEL1L3	9.59e-06	192	171	7	59261098ccb52306f837f632ebaea45b90ad30fe
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 SEMA5A DNAI3 IGSF10 PIEZO2 TENM3 CDH11	9.59e-06	192	171	7	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 ABCA13 SEMA5A SEL1L3 NFAT5 SLC27A2 DNAH11	9.92e-06	193	171	7	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRN1 ABCA13 ADAM28 KLF5 ALPL SLC27A2 PLCE1	1.10e-05	196	171	7	b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL	1.10e-05	196	171	7	020110cd79453df9546fb20802fe38ecadd9fe74
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL SLC27A2	1.10e-05	196	171	7	8e909c31733762646359fe78b645cbd60237459e
ToppCell	cellseq-Epithelial-Epithelial_Airway\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA13 ADAM28 PTPRF CLCA2 KLF5 TP63 SLC27A2	1.10e-05	196	171	7	faa39c567f24403e511b240c1d1a654ffadd8473
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANK2 DNAI3 IGSF10 TENM3 MACF1 CDH11 IL6ST	1.13e-05	197	171	7	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 ALPL SLC27A2	1.13e-05	197	171	7	ff19e4c45715752a04541ad6a0cdf5454c9daaa2
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-T_reticular\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 SPARC ANK2 FLRT2 CDH11 IL6ST TNS3	1.17e-05	198	171	7	5c96778cf5623c662c2259fe70f8665c14a161dd
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 ALPL SLC27A2	1.17e-05	198	171	7	778fee7020c82d11ff3984a8e482a23e5d58165f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STEAP4 HEPACAM2 CREB3L4 ADAM28 CLCA2 ALPL SLC27A2	1.17e-05	198	171	7	7896f9fb89822e8628fe0b90a489c4760c7b876c
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 SEMA5A ADAM28 CLCA2 TP63 SLC27A2 PLCE1	1.17e-05	198	171	7	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	MS-IIF-Others-HSPC\|IIF / Disease, condition lineage and cell class	PRSS57 CAT FAM171B CREB3L4 HOXA3 IGSF10 SLC27A2	1.21e-05	199	171	7	3384db80f6024bcabe2625f24d5f4e0d3d8caa7e
ToppCell	COVID-19-COVID-19_Severe-Others-HSPC\|COVID-19_Severe / Disease, condition lineage and cell class	PRSS57 FAM171B CREB3L4 HOXA3 IGSF10 TEC SLC27A2	1.21e-05	199	171	7	25de67b6c9c8d6bb9a538e071a40ef865906c95d
ToppCell	Control-Control-Others-HSPC\|Control / Disease, condition lineage and cell class	PRSS57 CREB3L4 TFR2 HOXA3 IGSF10 TEC SLC27A2	1.21e-05	199	171	7	b71169be0d916b2ed139a3122d78bb154c71edb4
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ANK2 SEMA5A IGSF10 TENM3 MACF1 CDH11 IL6ST	1.21e-05	199	171	7	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPARC MARK1 ITGA5 PIEZO2 TENM3 CSPG4 FLRT2	1.25e-05	200	171	7	b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPARC MARK1 ITGA5 PIEZO2 TENM3 CSPG4 FLRT2	1.25e-05	200	171	7	7c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TDRKH CTTNBP2 CREB3L4 ADAM28 GDPD5 PABPC1L	2.42e-05	149	171	6	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TDRKH CTTNBP2 CREB3L4 ADAM28 GDPD5 PABPC1L	2.51e-05	150	171	6	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEPACAM2 CEACAM16 PRMT7 KYNU TEC ZFP82	3.36e-05	158	171	6	66c011e9de002224f70725dfe8e7871c8d304492
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC CLCA2 PABPC1L FLRT2 NFAT5 PLCE1	3.74e-05	161	171	6	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC CLCA2 PABPC1L FLRT2 NFAT5 PLCE1	3.74e-05	161	171	6	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC CLCA2 PABPC1L FLRT2 NFAT5 PLCE1	3.74e-05	161	171	6	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC CLCA2 PABPC1L FLRT2 NFAT5 PLCE1	3.87e-05	162	171	6	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	severe-unassigned\|World / disease stage, cell group and cell class	PRSS57 HMGCS1 WARS2 AVIL PABPC1L ZNF841	4.14e-05	164	171	6	b3a45c150df6594debeeca400cc58d30ef662756
ToppCell	severe-unassigned\|severe / disease stage, cell group and cell class	PRSS57 HMGCS1 WARS2 AVIL PABPC1L ZNF841	4.28e-05	165	171	6	f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM201 STEAP4 HEPACAM2 CREB3L4 SEL1L3 SLC27A2	4.43e-05	166	171	6	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM201 STEAP4 HEPACAM2 CREB3L4 SEL1L3 SLC27A2	4.43e-05	166	171	6	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM201 STEAP4 HEPACAM2 CREB3L4 SEL1L3 SLC27A2	4.43e-05	166	171	6	4586d6725403f879fc96f67be579022587ce1906
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF391 HEPACAM2 ADAM28 TENM3 GSG1 PLCE1	4.74e-05	168	171	6	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	Ionocyte-iono-1\|World / Class top	RAPGEF4 HEPACAM2 CSPG4 CC2D2A SLC27A2 EPHA5	4.90e-05	169	171	6	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 ABCA13 CAT SEL1L3 TNS3 DNAH11	5.06e-05	170	171	6	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB2 FLNC CRTAC1 TP63 ZFP82 IL6ST	5.58e-05	173	171	6	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	10x5'-blood-Mast-Mast_cells\|blood / Manually curated celltypes from each tissue	PRSS57 ZNF112 ADAM28 GDPD5 KLF5 SLC27A2	5.76e-05	174	171	6	a5838821bba2be790d32331ff529d466e9974268
ToppCell	10x5'-blood-Mast\|blood / Manually curated celltypes from each tissue	PRSS57 ZNF112 ADAM28 GDPD5 KLF5 SLC27A2	5.76e-05	174	171	6	3a8a253213b207e3ff56f94a74996b8d9ad47aa1
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_MEMP\|lymph-node_spleen / Manually curated celltypes from each tissue	PRSS57 HEPACAM2 ITGA2B TFR2 IGSF10 SLC27A2	6.13e-05	176	171	6	23a8ec42ebd42c539865a12d09773af90f3f8848
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2orf69 STEAP4 ZFP14 LCLAT1 CSPG4 PABPC1L	6.33e-05	177	171	6	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2orf69 STEAP4 ZFP14 LCLAT1 CSPG4 PABPC1L	6.33e-05	177	171	6	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	FLNC DCHS2 RAPGEF4 PIEZO2 TENM3 FLRT2	6.53e-05	178	171	6	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC PIEZO2 MACF1 FLRT2 NFAT5 IL6ST	6.53e-05	178	171	6	ad3de3e03a401dac64431a541899445262246347
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 SEMA5A CRTAC1 SPAG9 TENM3 CEACAM16	6.53e-05	178	171	6	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SPARC RAPGEF4 SEMA5A TENM3 CDH11 ALPL	6.53e-05	178	171	6	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 SEMA5A ZFP14 HEPACAM2 CEACAM16 ZNF471	7.16e-05	181	171	6	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 SEMA5A ZFP14 HEPACAM2 CEACAM16 ZNF471	7.16e-05	181	171	6	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	CACNA2D1 MARK1 SEMA5A CLCA2 KLF5 TP63	7.16e-05	181	171	6	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 ABCA13 SEMA5A SEL1L3 TNS3 DNAH11	7.38e-05	182	171	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	(00)_Basal-(0)_uninjured\|(00)_Basal / shred by cell type and Timepoint	CACNA2D1 SPARC ARRB1 TP63 IL6ST ALPL	7.38e-05	182	171	6	c02c9cab4389d80f318f4bb8d703c1e719672624
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CREB3L4 ADAM28 CLCA2 SEL1L3 ALPL SLC27A2	7.38e-05	182	171	6	94e70746e35a3062015d4b83ee545f4f84f47420
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI1 FLNC DCHS2 LIMS4 ITGA2B FLRT2	7.61e-05	183	171	6	38a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 ADAM28 OVOL2 KLF5 TP63 ALPL	7.61e-05	183	171	6	ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCell	facs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 ADAM28 OVOL2 KLF5 TP63 ALPL	7.61e-05	183	171	6	f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 PIEZO2 DNAH9 EPHA5 PLCE1 DNAH11	7.84e-05	184	171	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	FLNC SPARC LRRN1 PIEZO2 HMCN2 CDH11	7.84e-05	184	171	6	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP\|bone_marrow / Manually curated celltypes from each tissue	PRSS57 ITGA2B TFR2 IGSF10 PIEZO2 SLC27A2	7.84e-05	184	171	6	b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 PIEZO2 DNAH9 EPHA5 PLCE1 DNAH11	7.84e-05	184	171	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 PIEZO2 DNAH9 EPHA5 PLCE1 DNAH11	7.84e-05	184	171	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 ABCA13 SEL1L3 NFAT5 TNS3 DNAH11	7.84e-05	184	171	6	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	SPARC STEAP4 SEMA5A CSPG4 CDH11 PLCE1	7.84e-05	184	171	6	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 CACNA2D1 MARK1 FAM171B IGSF10 PIEZO2	8.08e-05	185	171	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 CACNA2D1 MARK1 FAM171B IGSF10 PIEZO2	8.08e-05	185	171	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 CACNA2D1 MARK1 FAM171B IGSF10 PIEZO2	8.08e-05	185	171	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	CACNA2D1 MARK1 SEMA5A PIEZO2 CDH11 PLCE1	8.32e-05	186	171	6	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EPHB2 ANK2 HOXA3 TENM3 FLRT2 TNS3	8.32e-05	186	171	6	4d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPARC STEAP4 SEMA5A CSPG4 VSIG10L2 DNAH11	8.32e-05	186	171	6	0c477016c1b539b3086a8066c3c6443f08c222a3
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1B MARK1 STEAP4 CSPG4 SEL1L3 PLCE1	8.57e-05	187	171	6	dba4924d914a7dcd4901142684ba920c2404860b
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1B MARK1 STEAP4 CSPG4 SEL1L3 PLCE1	8.57e-05	187	171	6	9688141beef4f62613d7a810c5872ccb9afc1a71
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	CTTNBP2 STEAP4 LIMS3 SEL1L3 KYNU CDH11	8.57e-05	187	171	6	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	Healthy-HSPC\|World / disease group, cell group and cell class	PRSS57 CREB3L4 TFR2 HOXA3 IGSF10 SLC27A2	8.57e-05	187	171	6	8cd9e5499e5c2b2321ecbcf780df37fe0f165ac9
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CACNA2D1 MARK1 DNAI3 ZNF471 CDH11 ALPL	8.82e-05	188	171	6	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	SPARC PIEZO2 TENM3 CSPG4 FLRT2 CDH11	8.82e-05	188	171	6	7b1e3f8a941eaa68e89c562129a92314642eec66
Computational	Neighborhood of SUFU	UFSP2 ZFP14 SPAG9 KMT2A ZNF84 MED13	3.31e-05	77	86	6	GCM_SUFU
Disease	kynureninase measurement	KYNU ALPL	2.89e-05	2	159	2	EFO_0008201
Disease	neuroimaging measurement	MAGI1 DCHS2 CTTNBP2 LARP4 CREB3L4 WARS2 MAPK8IP3 ZNF106 NF1 BRCA1 TP63 CC2D2A MACF1 CDC5L CDH11 PLCE1 DNAH11	6.90e-05	1069	159	17	EFO_0004346
Disease	retinitis pigmentosa (is_implicated_in)	CAT MFRP CC2D2A RPE65	7.04e-05	41	159	4	DOID:10584 (is_implicated_in)
Disease	tyrosine-protein kinase TEC measurement	TEC TEC	1.72e-04	4	159	2	EFO_0020830
Disease	procollagen C-endopeptidase enhancer 1 measurement	TFR2 DNAH11	4.27e-04	6	159	2	EFO_0801920
Disease	intraocular pressure measurement	CTTNBP2 MFRP KBTBD7 MAPK8IP3 ZNF106 KLF5 CSPG4 KMT2A CDC5L CDH11	4.62e-04	509	159	10	EFO_0004695
Disease	uveal melanoma disease severity	MAGI1 DNAI3	5.95e-04	7	159	2	EFO_0010244
Disease	ovarian neoplasm	SPARC ATR BRCA1 TP63 IL6ST	8.14e-04	134	159	5	C0919267
Disease	Malignant neoplasm of ovary	SPARC ATR BRCA1 TP63 IL6ST	9.00e-04	137	159	5	C1140680
Disease	stroke	SPARC ANK2 ZNF106 PTPRF CDC5L	1.12e-03	144	159	5	EFO_0000712
Disease	Stomach Neoplasms	ATR MARK1 ITGA5 PTPRF KMT2A MUC6 PLCE1	1.18e-03	297	159	7	C0038356
Disease	corpus callosum anterior volume measurement	CTTNBP2 FAM171B DTWD2	1.22e-03	39	159	3	EFO_0010295
Disease	Malignant neoplasm of stomach	ATR MARK1 ITGA5 PTPRF KMT2A MUC6 PLCE1	1.25e-03	300	159	7	C0024623
Disease	glaucoma	CTTNBP2 KMT2A CDC5L CDH11 PLCE1	1.51e-03	154	159	5	MONDO_0005041
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 PLCE1	1.54e-03	11	159	2	DOID:3717 (is_implicated_in)
Disease	Malignant neoplasm of prostate	EPHB2 ATR STEAP4 CREB3L4 ADAM28 DHDH BRCA1 KMT2A ENPP5 IL6ST	1.94e-03	616	159	10	C0376358
Disease	corpus callosum volume measurement	CACNA2D1 CTTNBP2 FAM171B DTWD2	2.13e-03	100	159	4	EFO_0010299
Disease	C-reactive protein measurement	DCHS2 NUP210L DTNB CRTAC1 ZNF112 MAPK8IP3 ZNF106 PTPRF SMARCC2 MACF1 PCMTD2 NFAT5 TOP1 ALPL DNAH11	2.28e-03	1206	159	15	EFO_0004458
Disease	Metabolic Bone Disorder	ANKRD11 ALPL	2.52e-03	14	159	2	C0005944
Disease	Chromosome Breakage	CAT BRCA1	2.52e-03	14	159	2	C0376628
Disease	Chromosome Breaks	CAT BRCA1	2.52e-03	14	159	2	C0333704
Disease	Dupuytren Contracture	DCHS2 TAB2 PJA2 MROH1	2.82e-03	108	159	4	EFO_0004229
Disease	Osteopenia	ANKRD11 ALPL	2.89e-03	15	159	2	C0029453
Disease	Hepatitis	SPARC CAT	2.89e-03	15	159	2	C0019158
Disease	Intellectual Disability	ACTL6A MAPK8IP3 NF1 BRCA1 MTF1 SMARCC2 MACF1 MED13	3.03e-03	447	159	8	C3714756
Disease	multiple myeloma	CACNA2D1 DTNB ANKRD11 DNAH11	3.21e-03	112	159	4	EFO_0001378
Disease	Pheochromocytoma, Extra-Adrenal	DBH NF1	3.29e-03	16	159	2	C1257877
Disease	cytokine measurement	MAGI1 UFSP2 ANK2 ZNF112 MRPS22 FLRT2 CDH11 SLC27A2	3.65e-03	461	159	8	EFO_0004873
Disease	thyroxine measurement, triiodothyronine measurement	EPHB2 ZNF841	3.72e-03	17	159	2	EFO_0005130, EFO_0008392
Disease	Multiple congenital anomalies	TP63 KYNU	3.72e-03	17	159	2	C0000772
Disease	open-angle glaucoma	CTTNBP2 KLF5 KMT2A CDH11 PLCE1	3.84e-03	191	159	5	EFO_0004190
Disease	Colorectal Neoplasms	FLNC SPARC ABCA13 KLF5 TP63 IL6ST	4.00e-03	277	159	6	C0009404
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	TFR2 CEACAM16 TOP1 DNAH11	4.11e-03	120	159	4	EFO_0004611, EFO_0004639
Disease	cartilage thickness measurement	CDC5L DOT1L	4.17e-03	18	159	2	EFO_0007873
Disease	Alzheimer disease, polygenic risk score	PCDHGB1 ZNF112 LARP4 PRKD3 CEACAM16 RNF38 FLRT2 NFAT5 ALPL	4.64e-03	586	159	9	EFO_0030082, MONDO_0004975
Disease	cystathionine measurement	TEC TEC	4.65e-03	19	159	2	EFO_0010474
Disease	diet measurement, HOMA-B	MAGI1 NFAT5	4.65e-03	19	159	2	EFO_0004469, EFO_0008111
Disease	Pheochromocytoma	DBH NF1	4.65e-03	19	159	2	C0031511
Disease	neuroimaging measurement, brain volume measurement	CTTNBP2 ATR FAM171B NF1 DTWD2 NFAT5	4.67e-03	286	159	6	EFO_0004346, EFO_0006930
Disease	Adenocarcinoma of prostate	EPHB2 BRCA1	5.14e-03	20	159	2	C0007112
Disease	Malignant Neoplasms	ATR CAT BRCA1 TOP1	5.16e-03	128	159	4	C0006826
Disease	Hereditary Diffuse Gastric Cancer	MARK1 ITGA5 PTPRF KMT2A MUC6 PLCE1	5.24e-03	293	159	6	C1708349
Disease	Adenocarcinoma of lung (disorder)	ATR KLF5 TP63 DOT1L EPHA5	5.28e-03	206	159	5	C0152013

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDIVLTELGYPSQQH	TDRD5	686	Q8NAT2
YHHEAGVTALSQDPQ	ANKLE2	121	Q86XL3
LGGSPVQHREVQYHE	AVIL	86	O75366
GTNNSEHITYLEHNP	CDC5L	606	Q99459
TPLHDAANNGHYKVV	ANKRD11	236	Q6UB99
TDPQHHAYDTVENLA	CSPG4	746	Q6UVK1
AQTGIIVHTHVTPYQ	C2orf69	321	Q8N8R5
NFTEVHPDYGSHIQA	CAT	481	P04040
SPYSVGVVQDHSDNL	ADAM28	316	Q9UKQ2
YGHVQVHEILAQPTV	CEACAM16	121	Q2WEN9
IDPHTYEDPNQAVHE	EPHA5	651	P54756
HNQPIHSVSEGVDFY	GSG1	306	Q2KHT4
HTTAIPVHDGYVLQQ	ACTL6A	176	O96019
YGTVQPHTLIRQHID	DNAH11	2586	Q96DT5
LQQHGVAVTEPVYHL	ABCA13	246	Q86UQ4
HSRAEHTKENGLPYQ	DOT1L	801	Q8TEK3
HDGTVHTIQRSPFYN	DNAI3	671	Q8IWG1
ISTHLYIIQHPAEEN	DTWD2	91	Q8NBA8
ISHSVGEHLPNTYVD	CASP8AP2	1671	Q9UKL3
PAELHNVQSVHTVYL	FLRT2	81	O43155
EIYYHGEPISVNVHV	ARRB1	206	P49407
DREVHYHGEPISVNV	ARR3	201	P36575
EDTHHLVNYIPQGSI	HMGCS1	431	Q01581
NHSQDLHGYPTDQEL	MSANTD2	241	Q6P1R3
QDIYAVNGIAFHPVH	RAE1	271	P78406
HAHTYQHLQDVDIEP	SPAG9	1116	O60271
PLHIAAHYGNVNVAT	ANK2	236	Q01484
ISVPAGHSIELQFHN	MFRP	331	Q9BY79
GVQPEEISYINAHAT	OXSM	336	Q9NWU1
DRNYTVTGEEPHVQL	MUC6	941	Q6W4X9
IHHELEISTNPAQYA	KIAA0100	1756	Q14667
VYNHIGGEHSAVIPE	HHATL	351	Q9HCP6
PAETIVNSNGELYHE	LIMS3	81	P0CW19
PAETIVNSNGELYHE	LIMS4	81	P0CW20
IIVNGQETYDSPASH	MAGI1	581	Q96QZ7
AHTHQHLQDVDIEPY	MAPK8IP3	1116	Q9UPT6
GTISENTNYNHPHEA	LRRC37A2	1411	A6NM11
YTDLTGHHPSQGRIQ	HOXA3	421	O43365
EQGENIKHHYTPTAD	NRAP	996	Q86VF7
VGEAHRLYQVTVHVP	HMCN2	3836	Q8NDA2
LDAVHDITVAYPHNI	LCLAT1	251	Q6UWP7
HVNNSAYLPVHVNEE	DCAF4L2	311	Q8NA75
EAENYEGHTPLHVAV	NFKBIB	201	Q15653
QFDHPNVIHLEGVVT	EPHB2	676	P29323
GINHGIELHSDVVEY	PCMTD1	106	Q96MG8
GVNHGVELHSDVIEY	PCMTD2	106	Q9NV79
PVFHQASYVVHVSEN	PCDHGB1	446	Q9Y5G3
PYHNQIHAADVTQTV	PDE1B	221	Q01064
LTPNEVSVHEQEYGL	NEMP1	396	O14524
EVYEALTHAHPNLTV	ENPP5	281	Q9UJA9
EVLIHNNADGTYHIT	FLNC	1201	Q14315
YGIPQHAESHQLKNT	GANC	226	Q8TET4
EYVALPSEESHVHQE	PRKD3	231	O94806
TLEAVLHSGFPQHQV	GDPD5	376	Q8WTR4
PLDSETHNYQIVNHD	KBTBD7	551	Q8WVZ9
QEDLYLHVNSAHPGS	OVOL2	226	Q9BRP0
AAHSTYRVQEPAVHI	PABPC1L	511	Q4VXU2
AQGEHVLPAAQHSVY	MROH1	1106	Q8NDA8
YHDQHITLPVSVGIY	NFAT5	511	O94916
EYIHDETGGSHIKPQ	MACF1	2186	Q9UPN3
TLHGQPTYHQVQVSE	PASD1	716	Q8IV76
QVYNATIAEHAPVGH	DCHS2	666	Q6V1P9
YLVQPDITTCHDVHN	F2RL2	236	O00254
YQAQSAVPLRHETHG	ALPL	441	P05186
DLGPAVHHVYELINQ	ITGA5	821	P08648
VHHVYELINQGPSSI	ITGA5	826	P08648
PSHLIRVEGNSHAQY	TP63	261	Q9H3D4
YPLGHEVNHSRETSI	BRCA1	831	P38398
IQLEPDQIIHYHGVV	ATR	1726	Q13535
QSHIYRTGHEIPAEH	ATMIN	206	O43313
PLVEAYQENGIHHTV	IGSF10	571	Q6WRI0
NEGVADYIPFNHEHI	CBLIF	396	P27352
TVVHSGYRHQVPSVQ	IL6ST	761	P40189
DAVYSTGVHNIDVPN	CC2D2A	1576	Q9P2K1
PVVQGSALYLVAHHD	PRMT7	326	Q9NVM4
GRQISYQHAAVHIPT	CACNA2D1	156	P54289
YQHAAVHIPTDIYEG	CACNA2D1	161	P54289
HGPEGSLQDYIVHQL	CTTNBP2	1126	Q8WZ74
EGQVPHSLETLYQSA	FBXO7	176	Q9Y3I1
GHSDDLYAVPHRNQV	CEP89	151	Q96ST8
CIHEDQTVYIQPSHL	FRRS1	261	Q6ZNA5
EVHYHNPLVIEGRND	DBH	331	P09172
HETYHANVPERSNVG	CDH11	161	P55287
LQYSQDIPSHLADEH	DTNB	361	O60941
ERHNPTVTGHQEQTY	LARP4	411	Q71RC2
ENHTSVDGYTEPHIQ	MARK1	16	Q9P0L2
SVEVAYIGTQHPQHK	DHDH	66	Q9UQ10
SPSGEADEHYQLQHV	KMT2A	3441	Q03164
PTQLNYGVAVTDVDH	CRTAC1	51	Q9NQ79
DLHSTVYEVIQHIPA	HEPACAM2	441	A8MVW5
GTVQPHTIIRQHLDY	DNAH9	2556	Q9NYC9
DYQPHGVTSRNILTH	CREB3L4	326	Q8TEY5
PDNHHISNVTGYLTV	FAM171B	206	Q6P995
VDVHEYNLTHLQPST	LRRN1	576	Q6UXK5
GIHQNEDEPIRVSYH	OTUD5	316	Q96G74
THHDAVTVEPLYENG	NUP210L	71	Q5VU65
GHTEVPARNLYAHIQ	PTPRF	1611	P10586
TGEAQIHAHLVRPYV	POFUT1	221	Q9H488
VQLYHVLHPDGQSAQ	MRPS22	301	P82650
IEHQPNGGASVIHAY	RSBN1L	351	Q6PCB5
GQLYDHITEAVPQLH	PARS2	391	Q7L3T8
HQIPAYLVVEDHAQG	VARS2	531	Q5ST30
YKSTHVPVGEDQVQH	WARS2	171	Q9UGM6
YVSVNGATAHPHIEN	RPE65	171	Q16518
GATAHPHIENDGTVY	RPE65	176	Q16518
VAHYHAQPSQGTEQE	RAPGEF4	551	Q8WZA2
TPLDQHTLQGDQAYV	SEL1L3	641	Q68CR1
DIHDQLHQGTVPVSY	RNF38	186	Q9H0F5
GIIVNIIHNTSDYHP	TBC1D31	26	Q96DN5
LNHPDHYVETENIQH	TAB2	491	Q9NYJ8
HYVETENIQHLTDPT	TAB2	496	Q9NYJ8
GSIPEIIEYHKHNAA	TEC	321	P42680
LLQGATVIHYDQDTH	PLCE1	861	Q9P212
FVQEVNVYGVHVPDH	SLC27A2	506	O14975
HEAMSQGYVQHIISP	MTF1	86	Q14872
QGYVQHIISPDQIHL	MTF1	91	Q14872
QVFGIDALTTHPDYH	PRSS57	101	Q6UWY2
VHYEGHLQIAVADIP	MTG2	266	Q9H4K7
TPEVATKQYHEVIGH	SI	1201	P14410
NQHQPVYLLSEEHIT	MED13	181	Q9UHV7
VEHTYELHNNGPGTV	ITGA2B	811	P08514
QGSEHLYNDHGVIVD	TNS3	306	Q68CZ2
YSGTRHVVPAQVHVN	TNS3	451	Q68CZ2
NVTEQTHHIIIPSYA	SMARCC2	416	Q8TAQ2
EEAPSAHTLYVGHLN	SLFNL1	41	Q499Z3
YQQQSHDATVIHPVS	SEMA5A	996	Q13591
GPNFHQAHTTVIIDL	ATRAID	86	Q6UW56
QPNGETHESHRIYVA	CLCA2	851	Q9UQC9
QHVPFDIHTYGDQLV	NCAPH2	511	Q6IBW4
TPIIERESGGHHYVN	UFSP2	131	Q9NUQ7
LSPEHVEVYERTHGQ	PRM2	36	P04554
AGHVQTVHSPDIYRV	TNRC18	2176	O15417
SLNEHTNIHIGEKPY	ZNF876P	161	Q49A33
QLEDGTTAYIHHAVQ	ZNF143	136	P52747
TTAYIHHAVQVPQSD	ZNF143	141	P52747
LTQHQRIHTGEKPYE	ZNF135	481	P52742
LTQHQRIHTGEKPYE	ZSCAN30	456	Q86W11
TQHYENSVPEDLTVH	TDRKH	341	Q9Y2W6
GQLDQHPIDGYLSHT	SPARC	236	P09486
ADSVGHHLNQPEYIQ	TNPO2	546	O14787
HYHEATEPLEAINQL	ZNF75CP	56	Q92670
LVTVNGNPVDYHTIH	PIEZO2	416	Q9H5I5
IHGIVQSVVYHEESP	NF1	2681	P21359
SNAEYLAHLVPGAHV	STEAP4	116	Q687X5
GLDSHYQTEPHVLAG	TENM3	1711	Q9P273
IPAQYLEHLNHVVSS	TMEM201	86	Q5SNT2
LVQHQSIHTGEKPYE	ZNF780B	516	Q9Y6R6
LVQHQSIHAGVKPYE	ZNF780B	656	Q9Y6R6
LNTHQRIHTGEKPYE	ZNF84	586	P51523
LVIHTGENPYHCNEF	ZNF841	556	Q6ZN19
SYLQAHQRVHTGEKP	ZNF112	566	Q9UJU3
VHLDIQVGEHANNYP	TMED4	131	Q7Z7H5
SIQHQRVHTGEKPYE	ZNF621	306	Q6ZSS3
QLTQHQSIHIGEKPY	ZFP82	436	Q8N141
LTQHQRVHSGEKPYE	ZNF471	446	Q9BX82
NPGEVFHTVTLEQHE	ZNF415	111	Q09FC8
SLIQHQVVHTGERPY	ZNF416	536	Q9BWM5
GHYSQHSVLLVASQP	UEVLD	281	Q8IX04
SLTQHQRVHTGEKPY	ZNF570	456	Q96NI8
HVQRVHSEVKNGPTY	ZNF236	271	Q9UL36
TLVQHQIIHTGARPY	ZNF304	461	Q9HCX3
QLTQHQSIHTGEKPY	ZFP14	466	Q9HCL3
ALIQHQITHTGEKPY	ZNF354A	256	O60765
LTQHQRIHTGEKPYE	ZNF345	301	Q14585
RIEGHIGVQLQEHSY	ZNF407	796	Q9C0G0
HPQHSVEYEGNIHTS	TEX15	341	Q9BXT5
DLIQHQATHTGEKPY	ZNF629	276	Q9UEG4
LRDHTQVHTGPTYVI	VSIG10L2	281	P0DP72
TNLHNHSEGEYIPGA	PJA2	136	O43164
VQNGIALVHTDSYDP	PJA2	156	O43164
PSLSSQQAVYGHVHL	TFR2	311	Q9UP52
VDSPNHSGQTLYEQV	TFR2	536	Q9UP52
HINLHPELDGQEYVV	TOP1	511	P11387
YRVIQHQDTHSEGKP	ZNF584	116	Q8IVC4
QILQGLQETYEPSEH	ZNF106	1111	Q9H2Y7
QPFQYLEEVHISHVG	THAP4	446	Q8WY91
IIQHQRIHTGENPYE	ZNF391	236	Q9UJN7
YETIPQHINSTVHDL	ELFN2	46	Q5R3F8
LNQHERTHTGENPYE	ZNF554	451	Q86TJ5
DLHLSVPTQQGHLYQ	KLF5	216	Q13887
PSDHYAIESQLQLHG	KYNU	166	Q16719