Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	VMP1 CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 GJB4 ABCC8 KCNJ6 ATG2B LRP6 GJC2 GRID2 FLVCR2 ATP12A PKD1L3 ABCA7	6.46e-07	1289	66	17	GO:0005215
GeneOntologyMolecularFunction	channel activity	CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 GJB4 ABCC8 KCNJ6 GJC2 GRID2 PKD1L3	1.09e-06	525	66	11	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 GJB4 ABCC8 KCNJ6 GJC2 GRID2 PKD1L3	1.11e-06	526	66	11	GO:0022803
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	LHCGR CMKLR2 FLT1 LPAR4 GPR68 ABCC8 LPAR6 LRP6 GRID2 OR4K5 TSHR TAS2R45 RXFP3 PKD1L3 ABCA7 OR6X1 IFNAR2	1.27e-06	1353	66	17	GO:0004888
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 GJB4 ABCC8 KCNJ6 LRP6 GJC2 GRID2 FLVCR2 ATP12A PKD1L3 ABCA7	5.31e-06	1180	66	15	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 PKD1L3	1.69e-05	343	66	8	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GRID2 PKD1L3	1.92e-05	459	66	9	GO:0005216
GeneOntologyMolecularFunction	protein-hormone receptor activity	LHCGR CMKLR2 TSHR	5.08e-05	22	66	3	GO:0016500
GeneOntologyMolecularFunction	calcium channel activity	CACNA1D TPCN2 CATSPER2 TRPM7 PKD1L3	6.79e-05	129	66	5	GO:0005262
GeneOntologyMolecularFunction	lysophosphatidic acid receptor activity	LPAR4 LPAR6	1.07e-04	5	66	2	GO:0070915
GeneOntologyMolecularFunction	gated channel activity	CACNA1D PIEZO2 TPCN2 CATSPER2 ABCC8 KCNJ6 GRID2	1.15e-04	334	66	7	GO:0022836
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1D TPCN2 CATSPER2 TRPM7 PKD1L3	1.43e-04	151	66	5	GO:0015085
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1D TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 ATP12A PKD1L3	1.43e-04	465	66	8	GO:0046873
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1D TPCN2 CATSPER2 ABCC8 KCNJ6	1.47e-04	152	66	5	GO:0022843
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GRID2 ATP12A PKD1L3	2.59e-04	793	66	10	GO:0015075
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 ATP12A PKD1L3	3.21e-04	664	66	9	GO:0008324
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1D TPCN2 CATSPER2 ABCC8 KCNJ6	3.39e-04	182	66	5	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1D TPCN2 CATSPER2 ABCC8 KCNJ6	3.57e-04	184	66	5	GO:0022832
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	TPCN2 CATSPER2 ABCC8 KCNJ6 GRID2	4.44e-04	193	66	5	GO:0015276
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1D TPCN2 CATSPER2	4.73e-04	46	66	3	GO:0005245
GeneOntologyMolecularFunction	ligand-gated channel activity	TPCN2 CATSPER2 ABCC8 KCNJ6 GRID2	4.87e-04	197	66	5	GO:0022834
GeneOntologyMolecularFunction	G protein-coupled receptor activity	LHCGR CMKLR2 LPAR4 GPR68 LPAR6 OR4K5 TSHR TAS2R45 RXFP3 OR6X1	6.10e-04	884	66	10	GO:0004930
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1D TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 ATP12A PKD1L3	1.04e-03	627	66	8	GO:0022890
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TPCN2 CATSPER2 ABCC8 KCNJ6	1.19e-03	140	66	4	GO:0099094
GeneOntologyMolecularFunction	bioactive lipid receptor activity	LPAR4 LPAR6	1.25e-03	16	66	2	GO:0045125
GeneOntologyMolecularFunction	gap junction channel activity	GJB4 GJC2	3.07e-03	25	66	2	GO:0005243
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC8 MYO19 KIF21A HFM1 ATP12A ABCA7	3.33e-03	441	66	6	GO:0016887
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1D TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 ATP12A PKD1L3	3.42e-03	758	66	8	GO:0015318
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	ABCC8 KCNJ6	3.85e-03	28	66	2	GO:0005242
GeneOntologyMolecularFunction	taste receptor activity	TAS2R45 PKD1L3	5.32e-03	33	66	2	GO:0008527
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC8 ATP12A ABCA7	5.64e-03	109	66	3	GO:0042626
GeneOntologyMolecularFunction	wide pore channel activity	GJB4 GJC2	6.65e-03	37	66	2	GO:0022829
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	LHCGR TSHR RXFP3	9.74e-03	133	66	3	GO:0008528
GeneOntologyBiologicalProcess	metal ion transport	LHCGR VMP1 CACNA1D TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GJC2 FLVCR2 ATP12A PKD1L3 ALG10B NDFIP1	2.18e-06	1000	65	14	GO:0030001
GeneOntologyBiologicalProcess	monoatomic cation transport	LHCGR VMP1 CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GJC2 FLVCR2 ATP12A PKD1L3 ALG10B NDFIP1	2.29e-06	1157	65	15	GO:0006812
GeneOntologyBiologicalProcess	monoatomic ion transport	LHCGR VMP1 CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GJC2 GRID2 FLVCR2 ATP12A PKD1L3 ALG10B NDFIP1	3.96e-06	1374	65	16	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	LHCGR VMP1 CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GJC2 ATP12A PKD1L3 ALG10B	6.25e-06	942	65	13	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	LHCGR VMP1 CACNA1D PIEZO2 TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GJC2 GRID2 ATP12A PKD1L3 ALG10B	7.68e-06	1115	65	14	GO:0034220
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	LHCGR VMP1 CACNA1D TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GJC2 ATP12A PKD1L3 ALG10B	2.68e-05	922	65	12	GO:0098662
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	LHCGR VMP1 CACNA1D TPCN2 CATSPER2 TRPM7 GJC2 PKD1L3	3.11e-05	392	65	8	GO:0070588
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	LHCGR VMP1 CACNA1D TPCN2 CATSPER2 TRPM7 ABCC8 KCNJ6 GJC2 ATP12A PKD1L3 ALG10B	6.93e-05	1017	65	12	GO:0098660
GeneOntologyBiologicalProcess	intracellular magnesium ion homeostasis	TRPM7 XK	1.45e-04	6	65	2	GO:0010961
GeneOntologyBiologicalProcess	calcium ion transport	LHCGR VMP1 CACNA1D TPCN2 CATSPER2 TRPM7 GJC2 PKD1L3	1.91e-04	509	65	8	GO:0006816
GeneOntologyBiologicalProcess	positive regulation of apoptotic cell clearance	C3 ABCA7	2.70e-04	8	65	2	GO:2000427
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	LHCGR CACNA1D TSHR	2.72e-04	40	65	3	GO:0045762
GeneOntologyBiologicalProcess	regulation of presynapse assembly	FARP1 GRID2 LRRTM3	3.14e-04	42	65	3	GO:1905606
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport	LHCGR VMP1 CACNA1D GJC2	3.90e-04	109	65	4	GO:1904427
GeneOntologyBiologicalProcess	regulation of presynapse organization	FARP1 GRID2 LRRTM3	4.12e-04	46	65	3	GO:0099174
GeneOntologyBiologicalProcess	regulation of apoptotic cell clearance	C3 ABCA7	4.33e-04	10	65	2	GO:2000425
GeneOntologyBiologicalProcess	positive regulation of cyclase activity	LHCGR CACNA1D TSHR	4.67e-04	48	65	3	GO:0031281
GeneOntologyBiologicalProcess	response to pH	GPR68 ABCC8 PKD1L3	4.96e-04	49	65	3	GO:0009268
GeneOntologyBiologicalProcess	positive regulation of lyase activity	LHCGR CACNA1D TSHR	4.96e-04	49	65	3	GO:0051349
GeneOntologyBiologicalProcess	regulation of amyloid-beta formation	LRRTM3 ABCA7 RTN2	5.27e-04	50	65	3	GO:1902003
GeneOntologyBiologicalProcess	potassium ion import across plasma membrane	ABCC8 KCNJ6 ATP12A	5.58e-04	51	65	3	GO:1990573
GeneOntologyBiologicalProcess	positive regulation of insulin secretion involved in cellular response to glucose stimulus	CACNA1D GPR68 ABCC8	5.58e-04	51	65	3	GO:0035774
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1D TPCN2 CATSPER2 ABCC8 KCNJ6 GRID2 PKD1L3	3.50e-04	378	73	7	GO:0034702
GeneOntologyCellularComponent	transmembrane transporter complex	CACNA1D TPCN2 CATSPER2 ABCC8 KCNJ6 GRID2 ATP12A PKD1L3	4.70e-04	523	73	8	GO:1902495
GeneOntologyCellularComponent	endoplasmic reticulum membrane	VMP1 SC5D MARCHF8 ATG2B XK FLVCR2 HACD2 LNPK MARCHF1 RTN2 LCLAT1 ALG10B MAP3K5	4.87e-04	1293	73	13	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	VMP1 SC5D MARCHF8 ATG2B XK FLVCR2 HACD2 LNPK MARCHF1 RTN2 LCLAT1 ALG10B MAP3K5	5.08e-04	1299	73	13	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	VMP1 SC5D MARCHF8 ATG2B XK FLVCR2 HACD2 LNPK MARCHF1 RTN2 LCLAT1 ALG10B MAP3K5	6.22e-04	1327	73	13	GO:0042175
GeneOntologyCellularComponent	transporter complex	CACNA1D TPCN2 CATSPER2 ABCC8 KCNJ6 GRID2 ATP12A PKD1L3	6.54e-04	550	73	8	GO:1990351
GeneOntologyCellularComponent	cation channel complex	CACNA1D CATSPER2 ABCC8 KCNJ6 PKD1L3	1.39e-03	235	73	5	GO:0034703
GeneOntologyCellularComponent	cell surface	CACNA1D KCNJ6 LRP6 C3 TSHR PKD1L3 EPCAM ABCA7 RTN2 F10 MAP3K5	1.56e-03	1111	73	11	GO:0009986
GeneOntologyCellularComponent	plasma membrane protein complex	CACNA1D CATSPER2 GJB4 ABCC8 KCNJ6 LRP6 GJC2 GRID2 ATP12A	1.60e-03	785	73	9	GO:0098797
MousePheno	abnormal brown adipose tissue morphology	CMKLR2 SC5D GPR68 LRP6 C3 LCLAT1	3.24e-05	156	55	6	MP:0002971
MousePheno	abnormal erythrocyte magnesium level	TRPM7 XK	4.55e-05	3	55	2	MP:0012366
Domain	NPIP	NPIPB13 NPIPB3 NPIPB5 NPIPB2	1.66e-07	14	69	4	IPR009443
Domain	Gphrmn_rcpt_fam	LHCGR TSHR	2.00e-04	6	69	2	IPR002131
Domain	MARCH-like	MARCHF8 MARCHF1	3.71e-04	8	69	2	IPR033275
Domain	LRR_5	LHCGR TSHR	5.94e-04	10	69	2	PF13306
Domain	LRR_5	LHCGR TSHR	5.94e-04	10	69	2	IPR026906
Domain	RINGv	MARCHF8 MARCHF1	7.24e-04	11	69	2	PF12906
Domain	ZF_RING_CH	MARCHF8 MARCHF1	7.24e-04	11	69	2	PS51292
Domain	GPCR_Rhodpsn_7TM	LHCGR CMKLR2 LPAR4 GPR68 LPAR6 OR4K5 TSHR RXFP3 OR6X1	7.72e-04	670	69	9	IPR017452
Domain	7tm_1	LHCGR CMKLR2 LPAR4 GPR68 LPAR6 OR4K5 TSHR RXFP3 OR6X1	8.31e-04	677	69	9	PF00001
Domain	Ion_trans_dom	CACNA1D TPCN2 CATSPER2 TRPM7	8.39e-04	114	69	4	IPR005821
Domain	Ion_trans	CACNA1D TPCN2 CATSPER2 TRPM7	8.39e-04	114	69	4	PF00520
Domain	G_PROTEIN_RECEP_F1_1	LHCGR CMKLR2 LPAR4 GPR68 LPAR6 OR4K5 TSHR RXFP3 OR6X1	9.03e-04	685	69	9	PS00237
Domain	G_PROTEIN_RECEP_F1_2	LHCGR CMKLR2 LPAR4 GPR68 LPAR6 OR4K5 TSHR RXFP3 OR6X1	9.61e-04	691	69	9	PS50262
Domain	GPCR_Rhodpsn	LHCGR CMKLR2 LPAR4 GPR68 LPAR6 OR4K5 TSHR RXFP3 OR6X1	9.70e-04	692	69	9	IPR000276
Domain	FERM-adjacent	FARP1 FARP2	1.02e-03	13	69	2	IPR014847
Domain	FA	FARP1 FARP2	1.02e-03	13	69	2	SM01195
Domain	FA	FARP1 FARP2	1.02e-03	13	69	2	PF08736
Domain	Channel_four-helix_dom	CACNA1D TPCN2 CATSPER2	1.22e-03	57	69	3	IPR027359
Domain	-	CACNA1D TPCN2 CATSPER2	1.22e-03	57	69	3	1.20.120.350
Domain	Znf_RING-CH	MARCHF8 MARCHF1	1.76e-03	17	69	2	IPR011016
Domain	RINGv	MARCHF8 MARCHF1	1.76e-03	17	69	2	SM00744
Domain	CONNEXINS_1	GJB4 GJC2	2.21e-03	19	69	2	PS00407
Domain	CONNEXINS_2	GJB4 GJC2	2.45e-03	20	69	2	PS00408
Domain	Connexin	GJB4 GJC2	2.45e-03	20	69	2	IPR000500
Domain	Connexin_CCC	GJB4 GJC2	2.45e-03	20	69	2	IPR019570
Domain	Connexin_N	GJB4 GJC2	2.45e-03	20	69	2	IPR013092
Domain	Connexin	GJB4 GJC2	2.45e-03	20	69	2	PF00029
Domain	Connexin_CCC	GJB4 GJC2	2.45e-03	20	69	2	SM01089
Domain	Connexin_CS	GJB4 GJC2	2.45e-03	20	69	2	IPR017990
Domain	CNX	GJB4 GJC2	2.45e-03	20	69	2	SM00037
Domain	Ez/rad/moesin-like	FARP1 FARP2	2.70e-03	21	69	2	IPR000798
Domain	FERM_CS	FARP1 FARP2	3.52e-03	24	69	2	IPR019747
Domain	FERM_C	FARP1 FARP2	4.13e-03	26	69	2	PF09380
Domain	FERM_C	FARP1 FARP2	4.45e-03	27	69	2	SM01196
Domain	FERM_PH-like_C	FARP1 FARP2	4.45e-03	27	69	2	IPR018980
Domain	LRRNT	LHCGR LRIG1 LRRTM3	5.71e-03	98	69	3	IPR000372
Domain	LRRNT	LHCGR LRIG1 LRRTM3	5.71e-03	98	69	3	SM00013
Domain	FERM_N	FARP1 FARP2	6.60e-03	33	69	2	PF09379
Domain	FERM_N	FARP1 FARP2	6.60e-03	33	69	2	IPR018979
Pathway	REACTOME_GPCR_LIGAND_BINDING	LHCGR LPAR4 GPR68 LPAR6 C3 XK TSHR TAS2R45 RXFP3	1.73e-05	430	50	9	MM15160
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	LHCGR LPAR4 GPR68 LPAR6 C3 XK TSHR RXFP3	1.89e-05	330	50	8	M18334
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	LHCGR LPAR4 GPR68 LPAR6 C3 XK TSHR RXFP3	2.01e-05	333	50	8	MM14963
Pathway	REACTOME_GPCR_LIGAND_BINDING	LHCGR LPAR4 GPR68 LPAR6 C3 XK TSHR RXFP3	2.03e-04	463	50	8	M507
Pathway	WP_GPCRS_NONODORANT	LHCGR LPAR4 GPR68 LPAR6 TSHR RXFP3	3.38e-04	266	50	6	MM15843
Pathway	REACTOME_SIGNALING_BY_GPCR	LHCGR LPAR4 GPR68 LPAR6 C3 XK TSHR TAS2R45 RXFP3	3.91e-04	646	50	9	MM14962
Pathway	WP_NUCLEOTIDE_GPCRS	LPAR4 LPAR6	6.64e-04	11	50	2	M39422
Pathway	REACTOME_P2Y_RECEPTORS	LPAR4 LPAR6	6.64e-04	11	50	2	MM15049
Pathway	REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS	LHCGR TSHR	7.95e-04	12	50	2	M13070
Pathway	REACTOME_P2Y_RECEPTORS	LPAR4 LPAR6	7.95e-04	12	50	2	M10960
Pathway	WP_NUCLEOTIDE_GPCRS	LPAR4 LPAR6	7.95e-04	12	50	2	MM15953
Pubmed	Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes.	LPAR4 LPAR6	4.35e-06	2	73	2	26714589
Pubmed	Isolation of TSH and LH/CG receptor cDNAs from human thyroid: regulation by tissue specific splicing.	LHCGR TSHR	4.35e-06	2	73	2	2293030
Pubmed	Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice.	KCNJ6 GRID2	4.35e-06	2	73	2	8614556
Pubmed	The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.	C3 MUC5B	4.35e-06	2	73	2	29565179
Pubmed	Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A.	KIF21A KANK2	4.35e-06	2	73	2	34274317
Pubmed	Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2.	FARP1 FARP2	4.35e-06	2	73	2	23375260
Pubmed	Bcl-2, Bax and Bcl-x expression in neuronal apoptosis: a study of mutant weaver and lurcher mice.	KCNJ6 GRID2	4.35e-06	2	73	2	9754955
Pubmed	Molecular analysis of gene expression in the developing pontocerebellar projection system.	KCNJ6 GRID2	4.35e-06	2	73	2	12408845
Pubmed	Eleven amino acids (Lys-201 to Lys-211) and 9 amino acids (Gly-222 to Leu-230) in the human thyrotropin receptor are involved in ligand binding.	LHCGR TSHR	4.35e-06	2	73	2	1651314
Pubmed	An intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.	LHCGR TSHR	4.35e-06	2	73	2	18162522
Pubmed	A conserved Asn in transmembrane helix 7 is an on/off switch in the activation of the thyrotropin receptor.	LHCGR TSHR	4.35e-06	2	73	2	11312274
Pubmed	Distribution of serotonin, its metabolites and 5-HT transporters in the neostriatum of Lurcher and weaver mutant mice.	KCNJ6 GRID2	4.35e-06	2	73	2	11434974
Pubmed	Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact.	LPAR4 LPAR6	4.35e-06	2	73	2	28854359
Pubmed	Expression of neurotrophins and neurotrophin receptors in the cerebellum of mutant weaver and lurcher mice.	KCNJ6 GRID2	4.35e-06	2	73	2	9733904
Pubmed	MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.	MARCHF8 MARCHF1	4.35e-06	2	73	2	21757542
Pubmed	TRAIL-related death receptors in normal, Lurcher and weaver mutant mouse brain.	KCNJ6 GRID2	4.35e-06	2	73	2	15531086
Pubmed	Insights into differential modulation of receptor function by hinge region using novel agonistic lutropin receptor and inverse agonistic thyrotropin receptor antibodies.	LHCGR TSHR	4.35e-06	2	73	2	22309849
Pubmed	Distribution of dopamine transporters in basal ganglia of cerebellar ataxic mice by [125I]RTI-121 quantitative autoradiography.	KCNJ6 GRID2	1.30e-05	3	73	2	9460703
Pubmed	Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection.	MARCHF8 MARCHF1	1.30e-05	3	73	2	27503069
Pubmed	Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions.	LHCGR TSHR	1.30e-05	3	73	2	8747461
Pubmed	Membrane-associated RING-CH (MARCH) 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor.	MARCHF8 MARCHF1	1.30e-05	3	73	2	23606747
Pubmed	Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.	LHCGR TSHR	1.30e-05	3	73	2	11847099
Pubmed	Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.	KIF21A KANK2	1.30e-05	3	73	2	29183992
Pubmed	Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.	MARCHF8 MARCHF1	1.30e-05	3	73	2	38299743
Pubmed	Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.	LHCGR TSHR	1.30e-05	3	73	2	15889138
Pubmed	Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.	MARCHF8 MARCHF1	1.30e-05	3	73	2	23300075
Pubmed	Vestibular ganglion neurons survive the loss of their cerebellar targets.	KCNJ6 GRID2	1.30e-05	3	73	2	9926858
Pubmed	Divergent origins and concerted expansion of two segmental duplications on chromosome 16.	NPIPB3 NPIPB5	1.30e-05	3	73	2	11948212
Pubmed	Altered intracellular localization of the glutamate receptor channel delta 2 subunit in weaver and reeler Purkinje cells.	KCNJ6 GRID2	1.30e-05	3	73	2	9037414
Pubmed	Diverse effects of LPA4, LPA5 and LPA6 on the activation of tumor progression in pancreatic cancer cells.	LPAR4 LPAR6	1.30e-05	3	73	2	25849892
Pubmed	Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.	MARCHF8 MARCHF1	2.60e-05	4	73	2	27503071
Pubmed	The HLA-DRalpha chain is modified by polyubiquitination.	MARCHF8 MARCHF1	2.60e-05	4	73	2	19117940
Pubmed	Activation of Wnt/beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fluorouracil combination therapy for hepatocellular carcinoma.	EPCAM IFNAR2	2.60e-05	4	73	2	19401692
Pubmed	Dependence of parvalbumin expression on Purkinje cell input in the deep cerebellar nuclei.	KCNJ6 GRID2	2.60e-05	4	73	2	9514513
Pubmed	Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons.	ABCC8 KCNJ6	2.60e-05	4	73	2	10022826
Pubmed	Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4.	LPAR4 LPAR6	2.60e-05	4	73	2	31335323
Pubmed	The Purkinje cell class may extend beyond the cerebellum.	KCNJ6 GRID2	2.60e-05	4	73	2	2077109
Pubmed	Molecular mechanism of lysophosphatidic acid-induced hypertensive response.	LPAR4 LPAR6	4.33e-05	5	73	2	30804442
Pubmed	LPA1 , LPA2 , LPA4 , and LPA6 receptor expression during mouse brain development.	LPAR4 LPAR6	6.48e-05	6	73	2	30847983
Pubmed	The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase.	TRPM7 DDB1	6.48e-05	6	73	2	24855944
Pubmed	Expression of the metabotropic glutamate receptor mGluR1 alpha and the ionotropic glutamate receptor GluR1 in the brain during the postnatal development of normal mouse and in the cerebellum from mutant mice.	KCNJ6 GRID2	6.48e-05	6	73	2	8230318
Pubmed	Altered cleavage plane orientation with increased genomic aneuploidy produced by receptor-mediated lysophosphatidic acid (LPA) signaling in mouse cerebral cortical neural progenitor cells.	LPAR4 LPAR6	6.48e-05	6	73	2	33317583
Pubmed	International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels.	TPCN2 CATSPER2	6.48e-05	6	73	2	16382101
Pubmed	Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.	LPAR4 LPAR6	6.48e-05	6	73	2	11004484
Pubmed	Marginal zone B cells acquire dendritic cell functions by trogocytosis.	C3 MARCHF1	6.48e-05	6	73	2	35143312
Pubmed	Vestibular ganglion neurons survive hair cell defects in jerker, shaker, and Varitint-waddler mutants and downregulate calretinin expression.	KCNJ6 GRID2	9.06e-05	7	73	2	17663432
Pubmed	LPA2 promotes neuronal differentiation and neurite formation in neocortical development.	LPAR4 LPAR6	9.06e-05	7	73	2	35151977
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	TPCN2 ABCC8 KCNJ6 GJC2 TSHR RXFP3 ABCA7 NDFIP1	1.07e-04	697	73	8	28298427
Pubmed	Behavioral effects of neonatal lesions on the cerebellar system.	KCNJ6 GRID2	1.21e-04	8	73	2	25907855
Pubmed	Lysophosphatidic acid receptor expression in chronic lymphocytic leukemia leads to cell survival mediated though vascular endothelial growth factor expression.	FLT1 LPAR4	1.21e-04	8	73	2	19860625
Pubmed	Length of uninterrupted repeats determines instability at the unstable mouse expanded simple tandem repeat family MMS10 derived from independent SINE B1 elements.	GRID2 RTN2	1.21e-04	8	73	2	11210178
Pubmed	Interleukin-1 hyperproduction by in vitro activated peripheral macrophages from cerebellar mutant mice.	KCNJ6 GRID2	1.21e-04	8	73	2	2230805
Pubmed	Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry.	KCNJ6 GRID2	1.55e-04	9	73	2	16499884
Pubmed	Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.	UBR2 DDB1	1.55e-04	9	73	2	17855541
Pubmed	Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration.	KCNJ6 GRID2	1.93e-04	10	73	2	1565842
Pubmed	Lysophosphatidic acid induces neurite branch formation through LPA3.	LPAR4 LPAR6	1.93e-04	10	73	2	22465231
Pubmed	HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.	UBR2 DDB1	2.83e-04	12	73	2	17360488
Pubmed	Hereditary Spastic Paraplegia Overview	GJC2 GRID2 RTN2	3.22e-04	63	73	3	20301682
Pubmed	Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia.	FLT1 C3	3.34e-04	13	73	2	29279353
Pubmed	Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss.	LRP6 C3	3.89e-04	14	73	2	19015224
Pubmed	Lysophospholipid receptor nomenclature review: IUPHAR Review 8.	LPAR4 LPAR6	4.48e-04	15	73	2	24602016
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	VMP1 TRPM7 HACD2 LNPK MARCHF1 LCLAT1	4.57e-04	468	73	6	31056421
Pubmed	Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.	MARCHF8 MARCHF1	5.12e-04	16	73	2	14722266
Pubmed	Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling.	LRIG1 EPCAM	5.12e-04	16	73	2	35132078
Pubmed	Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for β-Cell Function During Aging.	ABCC8 EPCAM	5.79e-04	17	73	2	38905124
Pubmed	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	PCNX2 MARCHF1	5.79e-04	17	73	2	21490949
Pubmed	Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86.	MARCHF8 MARCHF1	6.51e-04	18	73	2	35411049
Pubmed	An expression atlas of connexin genes in the mouse.	GJB4 GJC2	6.51e-04	18	73	2	15081111
Pubmed	The novel mouse connexin39 gene is expressed in developing striated muscle fibers.	GJB4 GJC2	6.51e-04	18	73	2	15466892
Pubmed	YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.	LRIG1 EPCAM	6.51e-04	18	73	2	29249464
Pubmed	An update on connexin genes and their nomenclature in mouse and man.	GJB4 GJC2	7.26e-04	19	73	2	14681012
Pubmed	Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting.	LRIG1 MUC5B	7.26e-04	19	73	2	35294885
Pubmed	Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.	FLT1 LRP6	7.26e-04	19	73	2	21623369
Pubmed	Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage.	LHCGR TSHR	8.06e-04	20	73	2	20716560
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	LHCGR LPAR4 LPAR6 TSHR	8.47e-04	200	73	4	18240029
Pubmed	Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation.	FLT1 TSHR	8.89e-04	21	73	2	23707896
Pubmed	Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.	UBR2 DDB1	8.89e-04	21	73	2	22190037
Pubmed	Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.	LRIG1 FARP2	8.89e-04	21	73	2	25340873
Pubmed	The sequence and analysis of duplication-rich human chromosome 16.	NPIPB11 NPIPB3 NPIPB2	9.14e-04	90	73	3	15616553
Pubmed	Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.	ABCC8 ABCA7	1.07e-03	23	73	2	10708515
Pubmed	Stable association between G alpha(q) and phospholipase C beta 1 in living cells.	LPAR4 GPR68 LPAR6	1.07e-03	95	73	3	16754659
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	LHCGR FLT1 LRP6 TSHR IFNAR2	1.28e-03	383	73	5	19453261
Pubmed	Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome.	LRP6 FLVCR2	1.59e-03	28	73	2	32369449
Pubmed	Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.	LRP6 RTN2	1.94e-03	31	73	2	30254141
Cytoband	14q31	GALC GPR68 TSHR	3.09e-07	9	72	3	14q31
Cytoband	16p12.2	NPIPB4 NPIPB3 NPIPB5	2.77e-05	37	72	3	16p12.2
Cytoband	12q12	KIF21A ALG10B	2.50e-03	47	72	2	12q12
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	NPIPB4 NPIPB3 NPIPB5	2.55e-03	172	72	3	chr16p12
GeneFamily	Glycoprotein hormone receptors	LHCGR TSHR	2.34e-05	3	51	2	199
GeneFamily	Lysophosphatidic acid receptors	LPAR4 LPAR6	1.16e-04	6	51	2	205
GeneFamily	Ring finger proteins\|Membrane associated ring-CH-type fingers	MARCHF8 MARCHF1	4.22e-04	11	51	2	60
GeneFamily	Gap junction proteins	GJB4 GJC2	1.74e-03	22	51	2	314
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FARP1 FARP2	8.77e-03	50	51	2	1293
Coexpression	JINESH_BLEBBISHIELD_TRANSFORMED_STEM_CELL_SPHERES_DN	CMKLR2 CATSPER2 NPIPB13 SC5D NPIPB12 NPIPB11 NPIPB3 ABCA7	1.99e-06	302	73	8	M38975
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	UBR2 NPIPB4 MARCHF8 NPIPB11 ATG2B PKD1L3 ABCA7	2.79e-08	193	72	7	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PCNX2 LPAR6 C3 GRID2 MARCHF1 MAP3K5	8.76e-07	200	72	6	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PCNX2 LPAR6 C3 GRID2 MARCHF1 MAP3K5	8.76e-07	200	72	6	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PCNX2 LPAR6 C3 GRID2 MARCHF1 MAP3K5	8.76e-07	200	72	6	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PCNX2 LPAR6 C3 GRID2 MARCHF1 MAP3K5	8.76e-07	200	72	6	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PCNX2 LPAR6 C3 GRID2 MARCHF1 MAP3K5	8.76e-07	200	72	6	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	PCNX2 LPAR6 C3 GRID2 MARCHF1 MAP3K5	8.76e-07	200	72	6	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 GJB4 ABCC8 TP53I11 GRID2	8.28e-06	170	72	5	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 GJB4 ABCC8 TP53I11 GRID2	8.28e-06	170	72	5	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 GJB4 ABCC8 TP53I11 GRID2	8.28e-06	170	72	5	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MARCHF8 ABCC8 KCNJ6 EPCAM F10	1.12e-05	181	72	5	af031661af28f99d906d8e013b4949133b44a2e6
ToppCell	E17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 LPAR6 TP53I11	1.31e-05	187	72	5	e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCell	E17.5-Endothelial-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 LPAR6 TP53I11	1.31e-05	187	72	5	61b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCell	E17.5-Endothelial\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 LPAR6 TP53I11	1.42e-05	190	72	5	4fb76195ec9d6e0260a628eef6c2b3705acce787
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	VMP1 UBR2 TRPM7 HACD2 NPIPB5	1.45e-05	191	72	5	9454f642c3621370fa23640b631301346b300950
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FAT3 GRID2 LRRTM3	1.49e-05	192	72	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FAT3 GRID2 LRRTM3	1.57e-05	194	72	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FAT3 GRID2 LRRTM3	1.57e-05	194	72	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CACNA1D PIEZO2 FARP1 FAT3 LRRTM3	1.61e-05	195	72	5	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	CACNA1D PIEZO2 FAT3 KANK2 F10	1.69e-05	197	72	5	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	critical-Epithelial-FOXN4+\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LRIG1 C3 DEPDC1 KANK2 EPCAM	1.73e-05	198	72	5	6b160b3d6a2c1b1641c2c7dcec1a7ef38411fec9
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FARP1 KIF21A C3 FLVCR2 EPCAM	1.81e-05	200	72	5	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GJB4 C3 MUC5B ATP12A EPCAM	1.81e-05	200	72	5	df90b67490cd649de3e3a713762ffbc34a698899
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A C3 DEPDC1 EPCAM	2.36e-05	103	72	4	c11bb0238e81a42dad5d7687c9d22474129d803d
ToppCell	Goblet-gob-2\|World / Class top	LPAR4 PARPBP ALG10B IFNAR2	8.28e-05	142	72	4	9b058dc313d1f0edcd8473e342852632e17536a6
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHCGR KCNJ6 KIF21A XK	1.08e-04	152	72	4	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHCGR KCNJ6 KIF21A XK	1.08e-04	152	72	4	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NPIPB13 NPIPB11 C3 RTN2	1.11e-04	153	72	4	099382241971412f84b6feefb897360a74a41143
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 PIEZO2 CATSPER2 TP53I11	1.19e-04	156	72	4	1928c86deb3bcd01db4ae76919a351066aadb39a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRIG1 MYO19 LNPK RTN2	1.28e-04	159	72	4	08a1cd71eac4322fb313324f74fe8e37998f2d7d
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LRIG1 MYO19 LNPK RTN2	1.28e-04	159	72	4	9bdfa7f5aa7753fe25b787bd43d694b6093d77eb
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FARP1 NPIPB11 HACD2 LNPK	1.31e-04	160	72	4	70f3637dd0bcfcef421aa114f946fff0048f192e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CMKLR2 CFAP54 PIEZO2 GJC2	1.34e-04	161	72	4	fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LHCGR CACNA1D FAT3 LRRTM3	1.34e-04	161	72	4	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CMKLR2 CFAP54 PIEZO2 GJC2	1.34e-04	161	72	4	c53c461fc721a7960cef86662f49e2a495520701
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	PIEZO2 WDR64 GRID2 MARCHF1	1.41e-04	163	72	4	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLT1 LPAR4 LPAR6 TP53I11	1.41e-04	163	72	4	d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C3 MARCHF1 F10 SLC66A3	1.44e-04	164	72	4	6a113191ea91d103d21c5f056b1950217688ea26
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 C3 MUC5B EPCAM	1.51e-04	166	72	4	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 C3 MUC5B EPCAM	1.51e-04	166	72	4	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-MAIT\|ICU-NoSEP / Disease, Lineage and Cell Type	CACNA1D NPIPB4 LRIG1 KIF21A	1.51e-04	166	72	4	d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	1.51e-04	166	72	4	9e98e6070055bfc780becee52d77830e06b6d854
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 C3 MUC5B EPCAM	1.51e-04	166	72	4	4586d6725403f879fc96f67be579022587ce1906
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	1.55e-04	167	72	4	31633899aae852873a4887e72c621474b0a51a33
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GALC NPIPB4 PKD1L3 MARCHF1	1.55e-04	167	72	4	881f64db8dea3faa7588bf04d87c20924a4e5952
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DEPDC1 F10 MAP3K5 IFNAR2	1.62e-04	169	72	4	4db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell	facs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPAR4 EPCAM SLC66A3 FARP2	1.73e-04	172	72	4	65b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	1.77e-04	173	72	4	3aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	1.77e-04	173	72	4	e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCell	10x5'-Liver-Lymphocytic_T_CD8-Tnaive/CM_CD8\|Liver / Manually curated celltypes from each tissue	LPAR4 SC5D GJC2 NDFIP1	1.81e-04	174	72	4	03918ca51ae3b4c9c1a74769b08ea23f518286ba
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 PIEZO2 DEPDC1 PARPBP	1.93e-04	177	72	4	73ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	FLT1 XK DEPDC1 NPIPB2	2.02e-04	179	72	4	021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 FARP1 FAT3 MARCHF1	2.11e-04	181	72	4	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	Control-Epithelial_alveolar-AT_1-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A C3 FLVCR2 EPCAM	2.15e-04	182	72	4	a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Late_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NPIPB13 NPIPB11 C3 ABCA7	2.15e-04	182	72	4	f8257c884393f168f605d371e0840cfca8d3657e
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TP53I11 FLVCR2 MARCHF1 ABCA7	2.15e-04	182	72	4	03992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLT1 PIEZO2 LPAR6 TP53I11	2.15e-04	182	72	4	7af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCell	E18.5-samps-Endothelial\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLT1 PIEZO2 LPAR6 TP53I11	2.15e-04	182	72	4	e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC8 KCNJ6 LRRTM3 F10	2.15e-04	182	72	4	27a27a3eaeacb087c9601d5bb1c9e57cdfcd9d77
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D FAT3 GRID2 KANK2	2.20e-04	183	72	4	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CMKLR2 C3 DEPDC1 F10	2.24e-04	184	72	4	4a9f798c67b9998bffe44242b210cc1e224ff5b1
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC8 KCNJ6 TSHR F10	2.24e-04	184	72	4	1e6f86f9e379cd9f453f6b7185f681b44eb63e09
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	VMP1 UBR2 TRPM7 NPIPB5	2.29e-04	185	72	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Control-Epithelial_alveolar\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A C3 FLVCR2 EPCAM	2.29e-04	185	72	4	3937e026add96a396122139daf8011cfbc60e75c
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	2.34e-04	186	72	4	55fe25f4d0f2bc0fd4802a0a375169f2c41472fc
ToppCell	(5)_Glands_duct\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	FARP1 C3 MUC5B EPCAM	2.34e-04	186	72	4	ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	VMP1 UBR2 TRPM7 NPIPB5	2.34e-04	186	72	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	E17.5-Endothelial-unknown_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 TP53I11	2.38e-04	187	72	4	da885c26ccc5189b1ff1f607552e00a5c0e49e7e
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	CACNA1D PIEZO2 FAT3 GRID2	2.38e-04	187	72	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	E17.5-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 TP53I11	2.38e-04	187	72	4	1f358d02ec69d44dea2e2831af9473ed05dcf8cc
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPAR4 C3 KANK2 F10	2.38e-04	187	72	4	f0c4d93f75615e570e4465fd622e3124189618a1
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-stromal_related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPAR4 C3 KANK2 F10	2.38e-04	187	72	4	3ff57da09ed8394913fb683669d7bff84a936623
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	TRPM7 KIF21A LRRTM3 LCLAT1	2.38e-04	187	72	4	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FAT3 LRRTM3	2.48e-04	189	72	4	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D FAT3 GRID2 KANK2	2.48e-04	189	72	4	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CMKLR2 CFAP54 PIEZO2 GJC2	2.53e-04	190	72	4	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 GRID2 MAP3K5	2.53e-04	190	72	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CMKLR2 CFAP54 PIEZO2 GJC2	2.53e-04	190	72	4	be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CMKLR2 CFAP54 PIEZO2 GJC2	2.53e-04	190	72	4	09a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP54 FARP1 FAT3 MARCHF1	2.58e-04	191	72	4	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FLT1 PIEZO2 LPAR4 TP53I11	2.58e-04	191	72	4	44c596984c6196f6014e0e405dbe5560841e54ff
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D FAT3 GRID2 KANK2	2.58e-04	191	72	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	E16.5-samps-Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FLT1 PIEZO2 LPAR4 TP53I11	2.58e-04	191	72	4	e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCell	IPF-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	C3 MUC5B ATP12A MAP3K5	2.58e-04	191	72	4	267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	2.64e-04	192	72	4	c227ab1914191e839fc39c9adc2080026d4b04fc
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	2.64e-04	192	72	4	bf187a57a559ab732bb815892af45ca922966ac6
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C3 MUC5B ATP12A EPCAM	2.64e-04	192	72	4	f573b2d205bd4d053a548af3fe3ff9de7be0cd2b
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC8 KCNJ6 EPCAM F10	2.64e-04	192	72	4	8df4cfe1461819756138ff1180896238dca2787e
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 PIEZO2 LPAR4 TP53I11	2.64e-04	192	72	4	e4dd24aefdf13cd4206714f02fde2288f3173ffc
ToppCell	E15.5-Endothelial\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 TP53I11	2.64e-04	192	72	4	88cc7f14d031a0613d032eb01c93e88c72d3938f
ToppCell	Influenza_Severe-RBC\|Influenza_Severe / Disease group and Cell class	MARCHF8 ATG2B XK KANK2	2.64e-04	192	72	4	f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 PIEZO2 LPAR4 TP53I11	2.64e-04	192	72	4	a502e95f78f96ed060654a769c6a0cc5dc5fcfd9
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 PIEZO2 LPAR4 TP53I11	2.64e-04	192	72	4	3c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D PIEZO2 FAT3 LRRTM3	2.64e-04	192	72	4	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	E18.5-Endothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 PIEZO2 LPAR4 TP53I11	2.64e-04	192	72	4	cb55d30880237ab8dccf7f7bd31eb7dc5aba0583
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 PIEZO2 LPAR4 TP53I11	2.69e-04	193	72	4	f4dd52491254ce321bc4d0dad988a7ce5970f52d
ToppCell	E15.5-Endothelial-capillary_endothelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 TP53I11	2.69e-04	193	72	4	3b3ffba483d114e9036a6fc64895fc37fc19d3e5
ToppCell	E15.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 PIEZO2 LPAR4 TP53I11	2.69e-04	193	72	4	1719a741f8458f658e2965853020f485c22d6106
ToppCell	severe_influenza-RBC\|severe_influenza / disease group, cell group and cell class (v2)	MARCHF8 ATG2B XK KANK2	2.69e-04	193	72	4	ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCell	cellseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C3 MUC5B ATP12A EPCAM	2.74e-04	194	72	4	5402835d6b252276e458001949dd1cb5aa744b0e
Disease	Adenoma, Microcystic	CACNA1D TRPM7 TSHR	7.57e-05	36	67	3	C0205648
Disease	Adenoma, Monomorphic	CACNA1D TRPM7 TSHR	7.57e-05	36	67	3	C0205649
Disease	Adenoma, Basal Cell	CACNA1D TRPM7 TSHR	7.57e-05	36	67	3	C0205646
Disease	Follicular adenoma	CACNA1D TRPM7 TSHR	7.57e-05	36	67	3	C0205647
Disease	Papillary adenoma	CACNA1D TRPM7 TSHR	7.57e-05	36	67	3	C0205650
Disease	Adenoma, Trabecular	CACNA1D TRPM7 TSHR	7.57e-05	36	67	3	C0205651
Disease	Adenoma	CACNA1D TRPM7 TSHR	7.57e-05	36	67	3	C0001430
Disease	mental or behavioural disorder, substance abuse	FARP1 HFM1	7.57e-05	6	67	2	EFO_0000677, MONDO_0002491
Disease	waist-hip ratio, metabolic syndrome	KCNJ6 HFM1	1.81e-04	9	67	2	EFO_0000195, EFO_0004343
Disease	chronic kidney disease	LRIG1 MYO19 TSHR HACD2 MARCHF1	1.98e-04	235	67	5	EFO_0003884
Disease	uric acid measurement	VMP1 LRIG1 TRPM7 FAT3 HFM1 TSHR FARP2	4.64e-04	610	67	7	EFO_0004761
Disease	Kuhnt-Junius degeneration (is_implicated_in)	FLT1 C3	6.76e-04	17	67	2	DOID:10873 (is_implicated_in)
Disease	diastolic blood pressure, systolic blood pressure	CACNA1D FLT1 PIEZO2 TPCN2 LRIG1 PELP1 FARP1	8.06e-04	670	67	7	EFO_0006335, EFO_0006336
Disease	diet measurement, HOMA-B	PCNX2 FAT3	8.47e-04	19	67	2	EFO_0004469, EFO_0008111
Disease	chronic obstructive pulmonary disease (is_marker_for)	FLT1 C3 MUC5B	1.42e-03	97	67	3	DOID:3083 (is_marker_for)
Disease	neutrophil count, eosinophil count	VMP1 UBR2 ABCA7 NDFIP1	1.42e-03	213	67	4	EFO_0004833, EFO_0004842
Disease	sciatic neuropathy (biomarker_via_orthology)	CACNA1D ABCC8 C3	1.50e-03	99	67	3	DOID:11446 (biomarker_via_orthology)
Disease	visuospatial function measurement	FARP1 KCNJ6	1.59e-03	26	67	2	EFO_0803533
Disease	neutrophil count, basophil count	VMP1 UBR2 ABCA7 NDFIP1	1.70e-03	224	67	4	EFO_0004833, EFO_0005090
Disease	lysophosphatidylethanolamine 22:6 measurement	FARP1 KCNJ6	1.85e-03	28	67	2	EFO_0010371

Protein segments in the cluster

Peptide	Gene	Start	Entry
SERVRTYWIIIELKH	EPCAM	136	P16422
TVKREEIFYTIKLWA	AKR1C8	76	Q5T2L2
QTKVDITWILLLRYY	CFAP54	2791	Q96N23
VWKVPEVSRIFSSIY	CATSPER2	306	Q96P56
TWLTAYVVKVFSLAV	C3	1076	P01024
FLVVTLVSVFLVWKF	ALG10B	326	Q5I7T1
IRYVVKEVSLVWHLY	ATG2B	1546	Q96BY7
LAWIYSVTLTVKAVV	ABCA7	556	Q8IZY2
DYIKVSIRLVLTFLW	MUC5B	171	Q9HC84
AFPTSYKVVITLWIV	NPIPB3	66	Q92617
LYTAEKVIIRWTLLT	TP53I11	121	O14683
FTVSLSDVLLTWKYL	PARPBP	56	Q9NWS1
AFPTSYKVVITLWIV	NPIPB12	66	F8W0I5
ELSVYTLTVITLERW	LHCGR	451	P22888
LTSLVWVCIIYQTRK	LRIG1	806	Q96JA1
KLIYARLFDWLVSVI	MYO19	381	Q96H55
TFVGKVWLTVLVVFR	GJC2	21	Q5T442
YLTDIFTTLVDLKWR	KCNJ6	76	P48051
VWKTYLSKITIFIEV	LPAR4	196	Q99677
AILIWVYDEVRKLFI	ATP12A	1011	P54707
LYSLVKWYFIITIVI	LCLAT1	366	Q6UWP7
ILRVVTEYAWQKFII	GRID2	156	O43424
VIFITSYVRPVKFWE	PCNX2	1341	A6NKB5
SSYIIILVTVWLKSS	OR4K5	216	Q8NGD3
VEEVWRYVILIYLQT	DEPDC1	186	Q5TB30
IYWTDISLKTISRAF	LRP6	676	O75581
ITCVVWSLYVLIDRT	MARCHF8	166	Q5T0T0
AFPTSYKVVITLWIV	NPIPB5	66	A8MRT5
TWKTYLSRIVIFIEI	LPAR6	176	P43657
AFPTSYKVVITLWIV	NPIPB4	66	C9JG80
FLEIWYTTTVIPKLL	OR6X1	66	Q8NH79
TVRTKVYAILELWVQ	PELP1	426	Q8IZL8
ITCVVWSLYVLIDRT	MARCHF1	166	Q8TCQ1
VLTSTIVTLKWIGYI	IFNAR2	256	P48551
VEWIRSTLLYIRALK	HFM1	716	A2PYH4
AFPTSYKVVITLWIV	NPIPB11	66	E5RHQ5
SLIKWILIVRFSTYF	NDFIP1	156	Q9BT67
TERTYLKDLEVITSW	FARP1	551	Q9Y4F1
LFVIAWTITEIIRYS	HACD2	136	Q6Y1H2
TLIDLSWDIKYRIVS	FAT3	71	Q8TDW7
YSTVLSRIWLSVVFI	GJB4	16	Q9NTQ9
IWLDRSKTYKETTLV	FLVCR2	366	Q9UPI3
LKVAYTTVLQEWLRL	KANK2	616	Q63ZY3
IYTKVTAFLKWIDRS	F10	451	P00742
TERTYLKDLEVITVW	FARP2	546	O94887
RVEVTAKKWYTLTLT	GALC	621	P54803
KSVTFYWLVIVLVFL	CACNA1D	521	Q01668
STVRLYEWTTEKELR	DDB1	886	Q16531
AFPTSYKVVITLWIV	NPIPB13	66	A6NJU9
VSVVIWAKELLTSIY	GPR68	141	Q15743
TPAWYLKSIVETILI	MAP3K5	506	Q99683
EWLKTSLLLAVYKTV	RTN2	276	O75298
TEARVRILISVVYWV	RXFP3	76	Q9NSD7
LLRAIYFVSVIISVW	TAS2R45	236	P59539
VLVILLVIYVSWKRY	LRRTM3	431	Q86VH5
SLLGFYVITVVWARK	PKD1L3	706	Q7Z443
VYWTLAFITKTIKFV	ABCC8	141	Q09428
RSSVAEILKYTLWEV	CMKLR2	316	P46091
LVFTVSTSYIKVWDI	KIF21A	1401	Q7Z4S6
VSSYIIWVSVKEVSL	PIEZO2	946	Q9H5I5
WVTVTVLRYRKTAIK	SLC66A3	186	Q8N755
IAFPRSYKVVLTLWT	NPIPB2	46	A6NJ64
TITRVLYEVFIEWGI	ZBED1	246	O96006
KVVYLSLYILVNIWT	SC5D	191	O75845
KFLYRDVTWILLRTV	FLT1	581	P17948
AITFRYAVEILTWEK	UBR2	196	Q8IWV8
LVLFTSVLKTWVVVI	XK	226	P51811
WIESTLTKRECVYII	TRPM7	6	Q96QT4
YLVVLVVSLVDWTVS	TPCN2	161	Q8NHX9
IILWNFVTSTVKKVY	WDR64	671	B1ANS9
ELSVYTLTVITLERW	TSHR	506	P16473
TLTVITLERWYAITF	TSHR	511	P16473
YFSLEILVILKEWTS	VMP1	56	Q96GC9
IIWSIRTVIIFFFSK	LNPK	86	Q9C0E8