Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	medium-chain fatty acid omega-hydroxylase activity	CYP4A11 CYP4A22	3.01e-05	2	110	2	GO:0140981
GeneOntologyMolecularFunction	16-hydroxypalmitate dehydrogenase activity	CYP4A11 CYP4A22	3.01e-05	2	110	2	GO:0103002
GeneOntologyMolecularFunction	alpha-L-arabinofuranosidase activity	OTOGL OTOG	3.01e-05	2	110	2	GO:0046556
GeneOntologyBiologicalProcess	heart development	ADAM15 MATR3 TSC2 SKI RYR1 ADGRG6 SMYD4 PTPRJ PKD1 LRP6 KDM2A IFT122 FGFR1 ASB2 FOXH1	1.06e-05	757	109	15	GO:0007507
GeneOntologyBiologicalProcess	peripheral nervous system axon ensheathment	PMP22 CNTNAP1 SKI ADGRG6	2.68e-05	33	109	4	GO:0032292
GeneOntologyBiologicalProcess	myelination in peripheral nervous system	PMP22 CNTNAP1 SKI ADGRG6	2.68e-05	33	109	4	GO:0022011
GeneOntologyBiologicalProcess	arabinose metabolic process	OTOGL OTOG	2.77e-05	2	109	2	GO:0019566
GeneOntologyBiologicalProcess	vibrational conductance of sound to the inner ear	OTOGL OTOG	2.77e-05	2	109	2	GO:0055127
GeneOntologyBiologicalProcess	L-arabinose metabolic process	OTOGL OTOG	2.77e-05	2	109	2	GO:0046373
GeneOntologyBiologicalProcess	lauric acid metabolic process	CYP4A11 CYP4A22	8.27e-05	3	109	2	GO:0048252
GeneOntologyBiologicalProcess	neuromuscular junction development, skeletal muscle fiber	PMP22 CNTNAP1	8.27e-05	3	109	2	GO:0098529
GeneOntologyBiologicalProcess	Schwann cell development	PMP22 CNTNAP1 SKI ADGRG6	1.10e-04	47	109	4	GO:0014044
GeneOntologyBiologicalProcess	skeletal muscle fiber development	PMP22 CNTNAP1 SKI RYR1	1.30e-04	49	109	4	GO:0048741
GeneOntologyBiologicalProcess	circulatory system development	ADAM15 MATR3 LAMA4 TSC2 SKI HDAC7 SVEP1 RYR1 ADGRG6 SMYD4 PTPRJ PKD1 LRP6 KDM2A IFT122 FGFR1 ASB2 RAPGEF2 FOXH1	1.86e-04	1442	109	19	GO:0072359
GeneOntologyBiologicalProcess	myotube cell development	PMP22 CNTNAP1 SKI RYR1	1.90e-04	54	109	4	GO:0014904
GeneOntologyBiologicalProcess	Schwann cell differentiation	PMP22 CNTNAP1 SKI ADGRG6	2.05e-04	55	109	4	GO:0014037
GeneOntologyBiologicalProcess	embryonic heart tube development	LRP6 KDM2A IFT122 ASB2 FOXH1	2.18e-04	103	109	5	GO:0035050
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	PMP22 CLASP1 ADAM15 WNT8A MATR3 CNTNAP1 TSC2 SKI HDAC7 ADGRG6 PTPRJ PKD1 MTMR2 LRP6 KDM2A IFT122 FGFR1 HERC1 FOXH1	2.66e-04	1483	109	19	GO:0048646
GeneOntologyBiologicalProcess	negative regulation of granulocyte chemotaxis	DPP4 C5AR2	2.74e-04	5	109	2	GO:0071623
GeneOntologyBiologicalProcess	neuron-glial cell signaling	ADRA1D GABBR1	2.74e-04	5	109	2	GO:0150099
GeneOntologyBiologicalProcess	negative regulation of neutrophil chemotaxis	DPP4 C5AR2	2.74e-04	5	109	2	GO:0090024
GeneOntologyBiologicalProcess	neural tube closure	TSC2 SKI LRP6 KDM2A IFT122	3.35e-04	113	109	5	GO:0001843
GeneOntologyBiologicalProcess	animal organ morphogenesis	PAPPA2 ADAM15 WNT8A LRRK2 SKI RYR1 ADGRG6 NTN4 PKD1 LRP6 KDM2A IFT122 FGFR1 ASB2 FOXH1 USH2A FOXI1	3.49e-04	1269	109	17	GO:0009887
GeneOntologyBiologicalProcess	tube closure	TSC2 SKI LRP6 KDM2A IFT122	3.49e-04	114	109	5	GO:0060606
GeneOntologyBiologicalProcess	body morphogenesis	CLASP1 SKI LRP6 IFT122	3.67e-04	64	109	4	GO:0010171
GeneOntologyBiologicalProcess	forebrain generation of neurons	OTP LRP6 FGFR1 RAPGEF2	3.90e-04	65	109	4	GO:0021872
GeneOntologyBiologicalProcess	negative regulation of neutrophil migration	DPP4 C5AR2	4.09e-04	6	109	2	GO:1902623
GeneOntologyBiologicalProcess	proteasome-mediated ubiquitin-dependent protein catabolic process	PMP22 WWP2 UBR4 LRRK2 PSMD10 FBXL3 USP7 ASB2 AGAP3	4.19e-04	424	109	9	GO:0043161
GeneOntologyBiologicalProcess	myelin assembly	PMP22 CNTNAP1 MTMR2	4.27e-04	28	109	3	GO:0032288
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	CLASP1 TSC2 SKI NTN4 PKD1 LRP6 KDM2A IFT122 FGFR1 ASB2 FOXH1	4.37e-04	619	109	11	GO:0002009
GeneOntologyBiologicalProcess	primary neural tube formation	TSC2 SKI LRP6 KDM2A IFT122	4.42e-04	120	109	5	GO:0014020
GeneOntologyCellularComponent	extracellular matrix	PMP22 SPP2 WNT8A LAMA4 GPC6 ADAMTSL3 SVEP1 NTN4 OTOGL LOXL4 SRPX CTSG USH2A OTOG	1.22e-05	656	113	14	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	PMP22 SPP2 WNT8A LAMA4 GPC6 ADAMTSL3 SVEP1 NTN4 OTOGL LOXL4 SRPX CTSG USH2A OTOG	1.27e-05	658	113	14	GO:0030312
GeneOntologyCellularComponent	RAVE complex	DMXL2 DMXL1	8.66e-05	3	113	2	GO:0043291
GeneOntologyCellularComponent	cell surface	PMP22 DPP4 ADAM15 CUBN GPC6 CR1 ADGRG6 PLA2R1 CD5 PTPRJ CD163L1 SCARB1 PKD1 LRP6 CD69 SRPX IL2RA	9.63e-05	1111	113	17	GO:0009986
GeneOntologyCellularComponent	collagen-containing extracellular matrix	PMP22 SPP2 WNT8A LAMA4 GPC6 NTN4 LOXL4 SRPX CTSG USH2A	6.06e-04	530	113	10	GO:0062023
Domain	WD40_repeat_dom	DMXL2 FBXW9 UBR4 LRRK2 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	1.71e-08	297	108	13	IPR017986
Domain	Sushi	PAPPA2 CR1 CSMD3 SVEP1 SRPX IL2RA GABBR1	1.92e-08	52	108	7	PF00084
Domain	CCP	PAPPA2 CR1 CSMD3 SVEP1 SRPX IL2RA GABBR1	2.52e-08	54	108	7	SM00032
Domain	SUSHI	PAPPA2 CR1 CSMD3 SVEP1 SRPX IL2RA GABBR1	3.26e-08	56	108	7	PS50923
Domain	Sushi_SCR_CCP_dom	PAPPA2 CR1 CSMD3 SVEP1 SRPX IL2RA GABBR1	3.70e-08	57	108	7	IPR000436
Domain	WD40	DMXL2 FBXW9 LRRK2 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	4.90e-08	268	108	12	SM00320
Domain	ConA-like_dom	PAPPA2 CNTNAP1 LAMA4 SVEP1 RYR1 ADGRG6 NELL1 HERC1 TRIM47 USH2A ADGRD1	5.71e-08	219	108	11	IPR013320
Domain	WD40_repeat	DMXL2 FBXW9 LRRK2 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	5.76e-08	272	108	12	IPR001680
Domain	-	PAPPA2 CNTNAP1 LAMA4 SVEP1 ADGRG6 NELL1 USH2A ADGRD1	7.71e-08	95	108	8	2.60.120.200
Domain	WD40	DMXL2 FBXW9 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	3.11e-07	259	108	11	PF00400
Domain	-	DMXL2 FBXW9 LRRK2 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	5.11e-07	333	108	12	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	DMXL2 FBXW9 LRRK2 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	5.44e-07	335	108	12	IPR015943
Domain	WD_REPEATS_1	DMXL2 FBXW9 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	6.27e-07	278	108	11	PS00678
Domain	WD_REPEATS_2	DMXL2 FBXW9 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	6.50e-07	279	108	11	PS50082
Domain	WD_REPEATS_REGION	DMXL2 FBXW9 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	6.50e-07	279	108	11	PS50294
Domain	SRCR	MSR1 CD5 CD163L1 LOXL4	5.87e-06	21	108	4	PF00530
Domain	-	MSR1 CD5 CD163L1 LOXL4	1.22e-05	25	108	4	3.10.250.10
Domain	SR	MSR1 CD5 CD163L1 LOXL4	1.22e-05	25	108	4	SM00202
Domain	SRCR-like_dom	MSR1 CD5 CD163L1 LOXL4	1.43e-05	26	108	4	IPR017448
Domain	SRCR_1	MSR1 CD5 CD163L1 LOXL4	1.43e-05	26	108	4	PS00420
Domain	SRCR_2	MSR1 CD5 CD163L1 LOXL4	1.43e-05	26	108	4	PS50287
Domain	SRCR	MSR1 CD5 CD163L1 LOXL4	1.67e-05	27	108	4	IPR001190
Domain	EGF_1	ADAM15 CNTNAP1 LAMA4 CUBN SVEP1 NELL1 NTN4 LRP6 USH2A	1.73e-05	255	108	9	PS00022
Domain	Rav1p_C	DMXL2 DMXL1	3.31e-05	2	108	2	IPR022033
Domain	Rav1p_C	DMXL2 DMXL1	3.31e-05	2	108	2	PF12234
Domain	WD40_repeat_CS	FBXW9 WDFY4 WDR59 TLE4 STRN4 EIF3I HERC1	4.69e-05	164	108	7	IPR019775
Domain	Laminin_G_2	CNTNAP1 LAMA4 NELL1 USH2A	8.23e-05	40	108	4	PF02210
Domain	HYR	SVEP1 SRPX	9.90e-05	3	108	2	PS50825
Domain	HYR_dom	SVEP1 SRPX	9.90e-05	3	108	2	IPR003410
Domain	HYR	SVEP1 SRPX	9.90e-05	3	108	2	PF02494
Domain	EGF-like_dom	ADAM15 CNTNAP1 LAMA4 CUBN SVEP1 NELL1 LRP6 OTOG	9.97e-05	249	108	8	IPR000742
Domain	LamG	CNTNAP1 LAMA4 NELL1 USH2A	1.20e-04	44	108	4	SM00282
Domain	EGF-like_CS	ADAM15 CNTNAP1 LAMA4 CUBN SVEP1 NELL1 NTN4 LRP6	1.38e-04	261	108	8	IPR013032
Domain	LamGL	PAPPA2 USH2A	1.97e-04	4	108	2	SM00560
Domain	LamG-like	PAPPA2 USH2A	1.97e-04	4	108	2	IPR006558
Domain	Laminin_G	CNTNAP1 LAMA4 NELL1 USH2A	3.53e-04	58	108	4	IPR001791
Domain	EGF	ADAM15 CNTNAP1 LAMA4 CUBN SVEP1 NELL1 LRP6	4.33e-04	235	108	7	SM00181
Domain	EGF_3	ADAM15 CNTNAP1 CUBN SVEP1 NELL1 LRP6 OTOG	4.33e-04	235	108	7	PS50026
Domain	EGF_LAM_2	LAMA4 NTN4 USH2A	6.81e-04	30	108	3	PS50027
Domain	EGF_LAM_1	LAMA4 NTN4 USH2A	6.81e-04	30	108	3	PS01248
Domain	Abhydrolase_1	SERHL2 SERHL ABHD16B	7.51e-04	31	108	3	PF00561
Domain	AB_hydrolase_1	SERHL2 SERHL ABHD16B	9.04e-04	33	108	3	IPR000073
Domain	GPS	ADGRG6 PKD1 ADGRD1	9.88e-04	34	108	3	SM00303
Domain	GPCR_2_secretin-like_CS	ADGRG6 GLP2R ADGRD1	9.88e-04	34	108	3	IPR017983
Domain	EGF_Lam	LAMA4 NTN4 USH2A	1.08e-03	35	108	3	SM00180
Domain	GPS	ADGRG6 PKD1 ADGRD1	1.08e-03	35	108	3	PF01825
Domain	Laminin_EGF	LAMA4 NTN4 USH2A	1.08e-03	35	108	3	PF00053
Domain	GPS	ADGRG6 PKD1 ADGRD1	1.17e-03	36	108	3	PS50221
Domain	GPS	ADGRG6 PKD1 ADGRD1	1.27e-03	37	108	3	IPR000203
Domain	LAM_G_DOMAIN	CNTNAP1 LAMA4 USH2A	1.37e-03	38	108	3	PS50025
Domain	Laminin_EGF	LAMA4 NTN4 USH2A	1.37e-03	38	108	3	IPR002049
Domain	PTX	SVEP1 ADGRG6	1.45e-03	10	108	2	SM00159
Domain	GPCR_2_extracellular_dom	ADGRG6 GLP2R ADGRD1	1.59e-03	40	108	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRG6 GLP2R ADGRD1	1.59e-03	40	108	3	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRG6 GLP2R ADGRD1	1.59e-03	40	108	3	PS50227
Domain	Pentaxin-related	SVEP1 ADGRG6	1.76e-03	11	108	2	IPR001759
Domain	Pentaxin	SVEP1 ADGRG6	1.76e-03	11	108	2	PF00354
Domain	EGF_dom	CUBN NELL1	2.11e-03	12	108	2	IPR024731
Domain	EGF_3	CUBN NELL1	2.11e-03	12	108	2	PF12947
Domain	MIRO-like	LRRK2 AGAP3	2.48e-03	13	108	2	IPR013684
Domain	Roc	LRRK2 AGAP3	2.48e-03	13	108	2	PF08477
Domain	CUB	CUBN CSMD3 ADGRG6	2.86e-03	49	108	3	PF00431
Domain	7tm_2	ADGRG6 GLP2R ADGRD1	3.03e-03	50	108	3	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRG6 GLP2R ADGRD1	3.03e-03	50	108	3	PS00650
Domain	CUB	CUBN CSMD3 ADGRG6	3.03e-03	50	108	3	SM00042
Domain	-	ANKRD42 LRRK2 PSMD10 FANK1 ASB2 AGAP3	3.20e-03	248	108	6	1.25.40.20
Domain	-	CUBN CSMD3 ADGRG6	3.38e-03	52	108	3	2.60.120.290
Domain	FBOX	FBXW9 FBXL3 KDM2A	3.38e-03	52	108	3	SM00256
Domain	CUB	CUBN CSMD3 ADGRG6	3.57e-03	53	108	3	PS01180
Domain	Ankyrin_rpt-contain_dom	ANKRD42 LRRK2 PSMD10 FANK1 ASB2 AGAP3	3.60e-03	254	108	6	IPR020683
Domain	Laminin_N	NTN4 USH2A	3.77e-03	16	108	2	IPR008211
Domain	LamNT	NTN4 USH2A	3.77e-03	16	108	2	SM00136
Domain	LAMININ_NTER	NTN4 USH2A	3.77e-03	16	108	2	PS51117
Domain	Laminin_N	NTN4 USH2A	3.77e-03	16	108	2	PF00055
Domain	Ankyrin_rpt	ANKRD42 LRRK2 PSMD10 FANK1 ASB2 AGAP3	4.18e-03	262	108	6	IPR002110
Domain	CUB_dom	CUBN CSMD3 ADGRG6	4.39e-03	57	108	3	IPR000859
Domain	EGF_2	ADAM15 CNTNAP1 CUBN SVEP1 NELL1 LRP6	4.42e-03	265	108	6	PS01186
Domain	FN3	PAPPA2 FANK1 PTPRJ IGSF9 USH2A	4.43e-03	185	108	5	SM00060
Domain	GPCR_2_secretin-like	ADGRG6 GLP2R ADGRD1	5.07e-03	60	108	3	IPR000832
Domain	GPCR_2-like	ADGRG6 GLP2R ADGRD1	5.07e-03	60	108	3	IPR017981
Domain	EGF_extracell	ADAM15 SVEP1 NELL1	5.07e-03	60	108	3	IPR013111
Domain	EGF_2	ADAM15 SVEP1 NELL1	5.07e-03	60	108	3	PF07974
Domain	G_PROTEIN_RECEP_F2_4	ADGRG6 GLP2R ADGRD1	5.31e-03	61	108	3	PS50261
Domain	VWC_out	NELL1 OTOG	5.31e-03	19	108	2	SM00215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CRYBG2 UBR4 TSC2 MED13L HDAC7 WDR59 RYR1 MDN1 SCARB1 PKD1 STRN4 USP7 FGFR1 HERC1 AGAP3	3.05e-06	1105	113	15	35748872
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	EME1 WDR59 MAVS EIF3I HERC1 AGAP3	6.50e-06	139	113	6	25476789
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DMXL2 TOGARAM1 MED13L HEPH CEP72 KDM2A OGA	9.33e-06	225	113	7	12168954
Pubmed	Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.	CYP4A11 CYP4A22	1.05e-05	2	113	2	15611369
Pubmed	Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.	SERHL2 SERHL	1.05e-05	2	113	2	11352564
Pubmed	Gankyrin activates mTORC1 signaling by accelerating TSC2 degradation in colorectal cancer.	TSC2 PSMD10	1.05e-05	2	113	2	26975632
Pubmed	Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.	CYP4A11 CYP4A22	1.05e-05	2	113	2	23641057
Pubmed	Acrofacial dysostosis in a patient with the TSC2-PKD1 contiguous gene syndrome.	TSC2 PKD1	1.05e-05	2	113	2	11836366
Pubmed	The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.	CYP4A11 CYP4A22	1.05e-05	2	113	2	28912346
Pubmed	Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.	CYP4A11 CYP4A22	1.05e-05	2	113	2	24413902
Pubmed	Analysis of PKD1 for genomic deletion by multiplex ligation-dependent probe assay: absence of hot spots.	TSC2 PKD1	1.05e-05	2	113	2	18060739
Pubmed	TSC2/PKD1 contiguous gene syndrome, with emphasis on a case with an atypical mild polycystic kidney phenotype and a novel genetic variant.	TSC2 PKD1	1.05e-05	2	113	2	31176519
Pubmed	Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.	CYP4A11 CYP4A22	1.05e-05	2	113	2	8031839
Pubmed	Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.	CYP4A11 CYP4A22	1.05e-05	2	113	2	10860550
Pubmed	Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.	CYP4A11 CYP4A22	1.05e-05	2	113	2	11320253
Pubmed	Characterization of the CYP4A11 gene, a second CYP4A gene in humans.	CYP4A11 CYP4A22	1.05e-05	2	113	2	12464262
Pubmed	Diagnosis and genotype-phenotype correlation in patients with PKD1/TSC2 contiguous gene deletion syndrome.	TSC2 PKD1	1.05e-05	2	113	2	35142283
Pubmed	Polycystin 1 is required for the structural integrity of blood vessels.	TSC2 PKD1	1.05e-05	2	113	2	10677526
Pubmed	Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.	CYP4A11 CYP4A22	1.05e-05	2	113	2	15066132
Pubmed	The mouse homologue of the polycystic kidney disease gene (Pkd1) is a single-copy gene.	TSC2 PKD1	1.05e-05	2	113	2	8661056
Pubmed	20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.	CYP4A11 CYP4A22	1.05e-05	2	113	2	23825080
Pubmed	Renal Neoplasia in Polycystic Kidney Disease: An Assessment of Tuberous Sclerosis Complex-associated Renal Neoplasia and PKD1/TSC2 Contiguous Gene Deletion Syndrome.	TSC2 PKD1	1.05e-05	2	113	2	34876325
Pubmed	Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.	CYP4A11 CYP4A22	1.05e-05	2	113	2	16691295
Pubmed	The P450 gene superfamily: recommended nomenclature.	CYP4A11 CYP4A22	1.05e-05	2	113	2	3829886
Pubmed	Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.	CYP4A11 CYP4A22	1.05e-05	2	113	2	29277328
Pubmed	Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.	CYP4A11 CYP4A22	1.05e-05	2	113	2	21820496
Pubmed	Two novel gross deletions of TSC2 in Malaysian patients with tuberous sclerosis complex and TSC2/PKD1 contiguous deletion syndrome.	TSC2 PKD1	1.05e-05	2	113	2	24683199
Pubmed	Imaging features of tuberous sclerosis complex with autosomal-dominant polycystic kidney disease: a contiguous gene syndrome.	TSC2 PKD1	1.05e-05	2	113	2	25355409
Pubmed	Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.	CYP4A11 CYP4A22	1.05e-05	2	113	2	20943934
Pubmed	The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.	CYP4A11 CYP4A22	1.05e-05	2	113	2	2766933
Pubmed	Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.	CYP4A11 CYP4A22	1.05e-05	2	113	2	17112342
Pubmed	Similar phenotypes caused by mutations in OTOG and OTOGL.	OTOGL OTOG	1.05e-05	2	113	2	24378291
Pubmed	Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.	LRRK2 LRP6	1.05e-05	2	113	2	27013965
Pubmed	High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.	CYP4A11 CYP4A22	1.05e-05	2	113	2	30088983
Pubmed	Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.	CYP4A11 CYP4A22	1.05e-05	2	113	2	19208908
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CLASP1 TSC2 HDAC7 CEP72 TNRC6A STRN4 RAPGEF2 SNTB2 AGAP3	1.59e-05	446	113	9	24255178
Pubmed	Functional proteomics mapping of a human signaling pathway.	PAPPA2 WWP2 UBR4 LAMA4 SKI SVEP1 PKD1 KDM2A ASB2 HERC1	2.41e-05	591	113	10	15231748
Pubmed	Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice.	CYP4A11 CYP4A22	3.13e-05	3	113	2	2354437
Pubmed	Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress.	LRP6 FGFR1	3.13e-05	3	113	2	39191776
Pubmed	Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis.	CYP4A11 CYP4A22	3.13e-05	3	113	2	28270609
Pubmed	Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor.	TRPM2 RYR1	3.13e-05	3	113	2	26462735
Pubmed	A new homozygous HERC1 gain-of-function variant in MDFPMR syndrome leads to mTORC1 hyperactivation and reduced autophagy during cell catabolism.	TSC2 HERC1	3.13e-05	3	113	2	32921582
Pubmed	Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.	TSC2 PKD1	3.13e-05	3	113	2	19321600
Pubmed	H19/Mir-130b-3p/Cyp4a14 potentiate the effect of praziquantel on liver in the treatment of Schistosoma japonicum infection.	CYP4A11 CYP4A22	3.13e-05	3	113	2	37659685
Pubmed	p28(GANK) prevents degradation of Oct4 and promotes expansion of tumor-initiating cells in hepatocarcinogenesis.	WWP2 PSMD10	3.13e-05	3	113	2	22387393
Pubmed	IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes.	DPP4 MAVS	3.13e-05	3	113	2	31355779
Pubmed	A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.	CYP4A11 CYP4A22	3.13e-05	3	113	2	9271096
Pubmed	TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.	TSC2 HERC1	3.13e-05	3	113	2	16464865
Pubmed	Increased CD4(+) CD69(+) CD25(-) T cells in patients with hepatocellular carcinoma are associated with tumor progression.	CD69 IL2RA	3.13e-05	3	113	2	21557772
Pubmed	Mouse cathepsin D gene: molecular organization, characterization of the promoter, and chromosomal localization.	CYP4A11 CYP4A22	3.13e-05	3	113	2	8011168
Pubmed	The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.	CYP4A11 CYP4A22	3.13e-05	3	113	2	1991046
Pubmed	Concurrent Reduced Expression of Contiguous PKD1, TSC2 and NTHL1 Leading to Kidney Diseases and Multiple Diverse Renal Cancers.	TSC2 PKD1	3.13e-05	3	113	2	36581342
Pubmed	Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.	CYP4A11 CYP4A22	3.13e-05	3	113	2	19713718
Pubmed	Peroxisome proliferator activated receptor alpha regulates a male-specific cytochrome P450 in mouse liver.	CYP4A11 CYP4A22	3.13e-05	3	113	2	15313227
Pubmed	VEGF-PKD1-HDAC7 signaling promotes endothelial progenitor cell migration and tube formation.	HDAC7 PKD1	3.13e-05	3	113	2	24189120
Pubmed	Modulation of CD4 lateral interaction with lymphocyte surface molecules induced by HIV-1 gp120.	DPP4 CD5 IL2RA	4.26e-05	21	113	3	7539755
Pubmed	Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.	CYP4A11 CYP4A22	6.25e-05	4	113	2	8334987
Pubmed	Endogenous N-terminal Domain Cleavage Modulates α1D-Adrenergic Receptor Pharmacodynamics.	ADRA1D SNTB2	6.25e-05	4	113	2	27382054
Pubmed	Molecular characterization of the human immunoglobulin V lambda I germline gene repertoire.	IGLV1-50 IGLV1-40	6.25e-05	4	113	2	1495496
Pubmed	CD25 and CD69 induction by α4β1 outside-in signalling requires TCR early signalling complex proteins.	CD69 IL2RA	6.25e-05	4	113	2	23758320
Pubmed	PTEN phosphorylation and nuclear export mediate free fatty acid-induced oxidative stress.	WWP2 USP7	6.25e-05	4	113	2	24063548
Pubmed	Differences in metabolite burden of di(2-ethylhexyl)phthalate in pregnant and postpartum dams and their offspring in relation to drug-metabolizing enzymes in mice.	CYP4A11 CYP4A22	6.25e-05	4	113	2	22159897
Pubmed	Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.	RYR1 GABBR1	6.25e-05	4	113	2	22504960
Pubmed	Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR.	TSC2 PKD1	6.25e-05	4	113	2	20169078
Pubmed	Mapping of the azh locus to mouse chromosome 4.	CYP4A11 CYP4A22	6.25e-05	4	113	2	1552159
Pubmed	Altered expression of hepatic CYP2E1 and CYP4A in obese, diabetic ob/ob mice, and fa/fa Zucker rats.	CYP4A11 CYP4A22	6.25e-05	4	113	2	10049703
Pubmed	A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.	MAVS LRP6	6.25e-05	4	113	2	29626090
Pubmed	Phosphorylation of histone deacetylase 7 by protein kinase D mediates T cell receptor-induced Nur77 expression and apoptosis.	HDAC7 PKD1	6.25e-05	4	113	2	15738054
Pubmed	Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.	TSC2 PKD1	6.25e-05	4	113	2	19255143
Pubmed	The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.	TSC2 PKD1	6.25e-05	4	113	2	18845692
Pubmed	Salt modulates vascular response through adenosine A(2A) receptor in eNOS-null mice: role of CYP450 epoxygenase and soluble epoxide hydrolase.	CYP4A11 CYP4A22	6.25e-05	4	113	2	21161333
Pubmed	Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.	RYR1 TLE4 ASB2	9.23e-05	27	113	3	37995181
Pubmed	Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.	HDAC7 PKD1	1.04e-04	5	113	2	15623513
Pubmed	Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.	MSR1 SCARB1	1.04e-04	5	113	2	12376530
Pubmed	Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity.	CUBN SCARB1	1.04e-04	5	113	2	36936697
Pubmed	Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs.	CYP4A11 CYP4A22	1.04e-04	5	113	2	8363569
Pubmed	The oncoprotein Ski acts as an antagonist of transforming growth factor-beta signaling by suppressing Smad2 phosphorylation.	SKI FOXH1	1.04e-04	5	113	2	12732634
Pubmed	Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination.	WWP2 USP7	1.04e-04	5	113	2	36897111
Pubmed	Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.	RYR1 PKD1	1.04e-04	5	113	2	11818962
Pubmed	Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase.	CYP4A11 CYP4A22	1.04e-04	5	113	2	20427718
Pubmed	Mapping of guanylin to murine chromosome 4 and human chromosome 1p34-p35.	CYP4A11 CYP4A22	1.04e-04	5	113	2	7601480
Pubmed	Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid.	MSR1 SCARB1	1.04e-04	5	113	2	11240025
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CLASP1 WWP2 MATR3 TSC2 HDAC7 WDR59 MDN1 EIF3I RAPGEF2 OTOG AGAP3	1.18e-04	861	113	11	36931259
Pubmed	Peroxisome proliferator-activated receptor-α accelerates α-chlorofatty acid catabolism.	CYP4A11 CYP4A22	1.56e-04	6	113	2	28007964
Pubmed	Where CD4+CD25+ T reg cells impinge on autoimmune diabetes.	CD69 IL2RA	1.56e-04	6	113	2	16301745
Pubmed	The protooncogene Ski controls Schwann cell proliferation and myelination.	PMP22 SKI	1.56e-04	6	113	2	15312649
Pubmed	IL-18-induced expression of high-affinity IL-2R on murine NK cells is essential for NK-cell IFN-γ production during murine Plasmodium yoelii infection.	CD69 IL2RA	1.56e-04	6	113	2	26420375
Pubmed	Peroxisome proliferator-activated receptor alpha-responsive genes induced in the newborn but not prenatal liver of peroxisomal fatty acyl-CoA oxidase null mice.	CYP4A11 CYP4A22	1.56e-04	6	113	2	11461119
Pubmed	Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells.	CYP4A11 CYP4A22	1.56e-04	6	113	2	8798505
Pubmed	Organization of the distal end of mouse chromosome 4.	CYP4A11 CYP4A22	1.56e-04	6	113	2	3166417
Pubmed	Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes.	SVEP1 TNRC6A	1.56e-04	6	113	2	23386860
Pubmed	Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways.	MSR1 SCARB1	1.56e-04	6	113	2	17148552
Pubmed	Mouse uroporphyrinogen decarboxylase: cDNA cloning, expression, and mapping.	CYP4A11 CYP4A22	1.56e-04	6	113	2	8661721
Pubmed	An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.	ADRA1D MTMR2 CTSG IL2RA	1.67e-04	84	113	4	15123239
Pubmed	Joint influence of small-effect genetic variants on human longevity.	TSC2 SVEP1 ADGRD1	1.86e-04	34	113	3	20834067
Pubmed	Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules.	ADRA1D SNTB2	2.17e-04	7	113	2	26617989
Pubmed	Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements.	CLASP1 USP7	2.17e-04	7	113	2	29898993
Pubmed	Activation of PPAR-alpha in streptozotocin-induced diabetes is essential for resistance against acetaminophen toxicity.	CYP4A11 CYP4A22	2.17e-04	7	113	2	12958197
Pubmed	Generation of a transcriptional map for a 700-kb region surrounding the polycystic kidney disease type 1 (PKD1) and tuberous sclerosis type 2 (TSC2) disease genes on human chromosome 16p3.3.	TSC2 PKD1	2.17e-04	7	113	2	8828041
Pubmed	Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.	CYP4A11 CYP4A22	2.17e-04	7	113	2	18648086
Cytoband	16q22.1	NRN1L WWP2 SLC9A5 SNTB2	1.64e-04	110	113	4	16q22.1
Cytoband	22q11.2	IGLV1-50 IGLV1-47 IGLV1-44 IGLV1-40	2.29e-04	120	113	4	22q11.2
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 CR1 CSMD3 SVEP1 SRPX IL2RA GABBR1	1.10e-08	57	88	7	1179
GeneFamily	WD repeat domain containing	DMXL2 FBXW9 WDFY4 WDR59 DMXL1 TLE4 STRN4 WDR89 IFT122 EIF3I HERC1	5.73e-08	262	88	11	362
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	MSR1 CD163L1 SCARB1	2.99e-04	27	88	3	1253
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	DPP4 CR1 MSR1 CD5 PTPRJ CD69 FGFR1 IL2RA	6.66e-04	394	88	8	471
GeneFamily	Immunoglobulin lambda locus at 22q11.2	IGLV1-50 IGLV1-47 IGLV1-44 IGLV1-40	9.34e-04	89	88	4	353
Coexpression	AIZARANI_LIVER_C32_MVECS_3	HDAC7 ADGRG6 NTN4 FGFR1 SRPX SNTB2	1.65e-05	125	112	6	M39131
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA4 SVEP1 NELL1 NTN4 OTOGL SRPX OTOG	1.86e-05	191	112	7	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA4 SVEP1 NELL1 NTN4 SRPX USH2A OTOG	2.19e-05	196	112	7	M3008
Coexpression	NABA_MATRISOME	PAPPA2 ADAM15 WNT8A LAMA4 GPC6 ADAMTSL3 SVEP1 NELL1 NTN4 OTOGL RPTN LOXL4 SRPX CTSG OTOG	2.58e-05	1008	112	15	MM17056
Coexpression	NABA_MATRISOME	PAPPA2 ADAM15 WNT8A LAMA4 GPC6 ADAMTSL3 SVEP1 NELL1 NTN4 RPTN LOXL4 SRPX CTSG USH2A OTOG	3.17e-05	1026	112	15	M5889
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	DMXL2 TRPM2 C5AR2 CR1 WDFY4 RYR1 MSR1 CD163L1 IL2RA	1.66e-09	193	113	9	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA4 GPC6 ADAMTSL3 SVEP1 PLA2R1 ADRA1D SRPX ADGRD1	1.61e-08	175	113	8	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 CR1 WDFY4 RYR1 ADGRG6 MSR1 CD163L1 IL2RA	3.32e-08	192	113	8	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	DMXL2 TRPM2 CR1 WDFY4 MSR1 PTPRJ CD163L1 IL2RA	3.32e-08	192	113	8	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 CR1 WDFY4 RYR1 ADGRG6 MSR1 CD163L1 IL2RA	3.32e-08	192	113	8	d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	DMXL2 TRPM2 CR1 WDFY4 MSR1 PTPRJ CD163L1 IL2RA	3.45e-08	193	113	8	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	PMP22 DMXL2 TRPM2 CR1 RYR1 MSR1 CD163L1 IL2RA	3.45e-08	193	113	8	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 CR1 WDFY4 RYR1 ADGRG6 MSR1 CD163L1 IL2RA	3.45e-08	193	113	8	f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D231\|Adult / Lineage, Cell type, age group and donor	PMP22 DMXL2 TRPM2 RYR1 MSR1 CD163L1 SCARB1 NXPH3	3.59e-08	194	113	8	800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell	LA-08._Macrophage\|LA / Chamber and Cluster_Paper	DMXL2 TRPM2 C5AR2 CR1 WDFY4 MSR1 CD163L1 IL2RA	3.74e-08	195	113	8	5e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PMP22 DMXL2 TRPM2 C5AR2 CR1 CD163L1 IL2RA AGAP3	4.05e-08	197	113	8	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PMP22 DMXL2 TRPM2 C5AR2 CR1 CD163L1 IL2RA AGAP3	4.05e-08	197	113	8	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PMP22 TRPM2 CR1 WDFY4 RYR1 MSR1 CD163L1 IL2RA	4.21e-08	198	113	8	c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRPM2 C5AR2 CR1 WDFY4 RYR1 MSR1 CD163L1 IL2RA	4.55e-08	200	113	8	179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PMP22 LAMA4 GPC6 ADAMTSL3 SVEP1 GLP2R FGFR1 SRPX	4.55e-08	200	113	8	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRPM2 C5AR2 CR1 WDFY4 RYR1 MSR1 CD163L1 IL2RA	4.55e-08	200	113	8	ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PMP22 LAMA4 GPC6 ADAMTSL3 SVEP1 FGFR1 SRPX ADGRD1	4.55e-08	200	113	8	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PMP22 LRRK2 LAMA4 ADAMTSL3 SVEP1 FGFR1 SRPX ADGRD1	4.55e-08	200	113	8	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PMP22 LAMA4 GPC6 ADAMTSL3 SVEP1 FGFR1 SRPX ADGRD1	4.55e-08	200	113	8	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PMP22 LAMA4 GPC6 ADAMTSL3 SVEP1 FGFR1 SRPX ADGRD1	4.55e-08	200	113	8	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PMP22 LRRK2 LAMA4 ADAMTSL3 SVEP1 FGFR1 SRPX ADGRD1	4.55e-08	200	113	8	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DMXL2 TRPM2 WDFY4 MSR1 PTPRJ CD163L1 FOXH1	2.68e-07	170	113	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA4 GPC6 ADAMTSL3 SVEP1 PLA2R1 ADRA1D SRPX	4.57e-07	184	113	7	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	TRPM2 CR1 WDFY4 MSR1 PTPRJ CD163L1 IL2RA	5.88e-07	191	113	7	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	DMXL2 TRPM2 LRRK2 WDFY4 MSR1 CD163L1 IL2RA	5.88e-07	191	113	7	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CNTNAP1 THSD7B GPC6 SVEP1 FADS3 SRPX ADGRD1	5.88e-07	191	113	7	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA4 GPC6 ADAMTSL3 SVEP1 PLA2R1 FGFR1 ADGRD1	5.88e-07	191	113	7	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Late_pre-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SERHL2 IGLV1-50 IGLV1-47 IGLV1-44 IGLV1-40 FADS3 CD69	5.88e-07	191	113	7	2b05be1888cccd03a32341bcb1de4a899d4179fd
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PMP22 LAMA4 SVEP1 FGFR1 SRPX ADGRD1 SNTB2	6.09e-07	192	113	7	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	TRPM2 CR1 WDFY4 MSR1 PTPRJ CD163L1 IL2RA	6.09e-07	192	113	7	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PMP22 LAMA4 SVEP1 FGFR1 SRPX ADGRD1 SNTB2	6.09e-07	192	113	7	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	LAMA4 GPC6 ADAMTSL3 SVEP1 GLP2R FGFR1 SRPX	6.09e-07	192	113	7	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PMP22 GPC6 ADAMTSL3 SVEP1 FGFR1 SRPX ADGRD1	6.09e-07	192	113	7	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TRPM2 LRRK2 C5AR2 CR1 WDFY4 CD163L1 CTSG	6.31e-07	193	113	7	c9e3fefa8d68d0e2b954f85ce37813185ff98d84
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DMXL2 TRPM2 CR1 WDFY4 RYR1 MSR1 IL2RA	6.31e-07	193	113	7	bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA4 GPC6 ADAMTSL3 SVEP1 GLP2R FGFR1 SRPX	6.31e-07	193	113	7	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DMXL2 TRPM2 CR1 WDFY4 RYR1 MSR1 IL2RA	6.31e-07	193	113	7	374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PMP22 LAMA4 GPC6 ADAMTSL3 SRPX ADGRD1 SNTB2	6.31e-07	193	113	7	160691b671710be10220803d788c2c961c236af1
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DMXL2 TRPM2 CR1 WDFY4 MSR1 PTPRJ CD163L1	6.53e-07	194	113	7	f09675cd472200363c458952f00d2e41990800ee
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 LAMA4 ADAMTSL3 HDAC7 NTN4 FGFR1 ADGRD1	6.53e-07	194	113	7	7b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	DMXL2 TRPM2 CR1 WDFY4 MSR1 CD163L1 IL2RA	6.53e-07	194	113	7	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 CR1 WDFY4 RYR1 MSR1 CD163L1 IL2RA	6.53e-07	194	113	7	0866ab6792cee274a71991d5c37a37f574ff446e
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PMP22 DMXL2 TRPM2 C5AR2 MSR1 PTPRJ CD163L1	6.53e-07	194	113	7	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	DMXL2 TRPM2 CR1 WDFY4 MSR1 CD163L1 IL2RA	6.76e-07	195	113	7	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	DMXL2 TRPM2 CR1 WDFY4 MSR1 PTPRJ CD163L1	6.76e-07	195	113	7	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	TRPM2 LRRK2 CR1 WDFY4 MSR1 CD163L1 IL2RA	6.76e-07	195	113	7	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRPM2 C5AR2 CR1 RYR1 MSR1 CD163L1 IL2RA	6.76e-07	195	113	7	312d9625655b38f1a7c2bf8f8bb7b667ebdf9617
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	DMXL2 TRPM2 CR1 WDFY4 MSR1 PTPRJ CD163L1	6.99e-07	196	113	7	a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell	COPD-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	PMP22 DMXL2 TRPM2 C5AR2 CD163L1 FGFR1 AGAP3	7.74e-07	199	113	7	1cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRPM2 C5AR2 CR1 WDFY4 RYR1 MSR1 CD163L1	7.74e-07	199	113	7	9545ac59c8d75f5747dff86cb511a149dc103b31
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PMP22 LAMA4 GPC6 SVEP1 FGFR1 SRPX ADGRD1	8.01e-07	200	113	7	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRPM2 C5AR2 CR1 WDFY4 RYR1 MSR1 CD163L1	8.01e-07	200	113	7	f3dc07a7cc8cf041da8fe610d21af595818cf2d8
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PMP22 LAMA4 GPC6 SVEP1 GLP2R FGFR1 SRPX	8.01e-07	200	113	7	17ffdbc13332bd3ed1d54abcd7af20267dd4b234
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DMXL2 TRPM2 C5AR2 CR1 WDFY4 MSR1 PTPRJ	8.01e-07	200	113	7	5432bdf495431cd26f6e4cd585100f3652588913
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PMP22 LAMA4 GPC6 SVEP1 GLP2R FGFR1 SRPX	8.01e-07	200	113	7	665df8391d2ebcfc6536318612f4992852b5e2b8
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DMXL2 C5AR2 CR1 WDFY4 MSR1 PTPRJ KDM1B	8.01e-07	200	113	7	8872d5fa101d413fb43b4231d476878678543035
ToppCell	Biopsy_IPF-Mesenchymal-Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	PAPPA2 LAMA4 ADAMTSL3 SVEP1 GLP2R FGFR1 SRPX	8.01e-07	200	113	7	d8637f1e62d3fb9476dc51e1b1dc2f4b14b5fcd8
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PMP22 LAMA4 GPC6 SVEP1 FGFR1 SRPX ADGRD1	8.01e-07	200	113	7	7ba292c30d915e66ebc8026fa76492cedf64700e
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PMP22 LAMA4 GPC6 ADAMTSL3 SVEP1 GLP2R SRPX	8.01e-07	200	113	7	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CNTNAP1 ADRA1D FANK1 CD5 OGA IL2RA	1.02e-06	130	113	6	d47d4ff1263815896470d854d25306eb36919e70
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CNTNAP1 ADRA1D FANK1 CD5 OGA IL2RA	1.02e-06	130	113	6	ad57b210c96caedadc1027b4d7a56b1bc389b137
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNHD1 DPP4 NTN4 CD5 PKD1 IL2RA	3.28e-06	159	113	6	b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMPRSS11E TRPM2 GPC6 ZNF575 TRIM47 FOXI1	4.35e-06	167	113	6	49d9220f22d10ff06c0512c9c40c26ad51728e4f
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMPRSS11E TRPM2 GPC6 ZNF575 TRIM47 FOXI1	4.35e-06	167	113	6	7ec032a98a13504d15c7e3a4e259278d07f40180
ToppCell	3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMPRSS11E TRPM2 GPC6 ZNF575 TRIM47 FOXI1	4.35e-06	167	113	6	5e3588eee73693a996bb4846427cf0038ceafbca
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 C5AR2 CR1 MSR1 CD163L1 IL2RA	4.50e-06	168	113	6	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 C5AR2 CR1 MSR1 CD163L1 IL2RA	4.50e-06	168	113	6	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPP4 THSD7B ADGRG6 TLE4 FGFR1 NXPH3	4.66e-06	169	113	6	1c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 WDFY4 RYR1 IFT122 FGFR1 ASB2	4.66e-06	169	113	6	46f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 WDFY4 RYR1 IFT122 FGFR1 ASB2	4.66e-06	169	113	6	9c9bb1b32fc6e22359424a262178906c3954415d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTSL3 ADGRG6 ADRA1D OTOGL ADGRD1 GABBR1	4.82e-06	170	113	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPP4 ADAMTSL3 CD5 CEP72 CD69 IL2RA	6.27e-06	178	113	6	f94e306b9550f3d1b5de0bb806790c17823d439e
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PMP22 GPC6 ADAMTSL3 SVEP1 FGFR1 SRPX	6.48e-06	179	113	6	dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPP2 TMPRSS11E TRPM2 GPC6 TRIM47 FOXI1	7.12e-06	182	113	6	6e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPP2 TMPRSS11E TRPM2 GPC6 TRIM47 FOXI1	7.12e-06	182	113	6	cd972d30519db706477c6b0c901165b81b74abed
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 LAMA4 SVEP1 SRPX IL2RA ADGRD1	7.35e-06	183	113	6	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 LAMA4 SVEP1 SRPX IL2RA ADGRD1	7.35e-06	183	113	6	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PMP22 GPC6 SVEP1 OTOGL FGFR1 SRPX	7.35e-06	183	113	6	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 LAMA4 SVEP1 SRPX IL2RA ADGRD1	7.35e-06	183	113	6	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-6_RORB_HPCA\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPP4 LAMA4 THSD7B GPC6 NTN4 ADGRD1	7.35e-06	183	113	6	c7e94fe3e7669db9304b249979fef7a69c30a143
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	DMXL2 WDFY4 RYR1 FANK1 ASB2 IL2RA	7.35e-06	183	113	6	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTSL3 ADGRG6 ADRA1D LRP6 SRPX ADGRD1	7.58e-06	184	113	6	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	GPC6 ADAMTSL3 SVEP1 GLP2R FGFR1 SRPX	7.58e-06	184	113	6	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	10x5'-blood-Myeloid_Dendritic-DC1\|blood / Manually curated celltypes from each tissue	WDFY4 RYR1 ADGRG6 ICAM5 KDM1B ASB2	7.58e-06	184	113	6	09fa465d1852b9b7e0405c27d4e5de276c9ba871
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	PMP22 DMXL2 TRPM2 CR1 RYR1 CD163L1	7.82e-06	185	113	6	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	LAMA4 GPC6 ADAMTSL3 SVEP1 GLP2R SRPX	7.82e-06	185	113	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PMP22 GPC6 ADGRG6 NELL1 ASB2 ADGRD1	8.06e-06	186	113	6	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DMXL2 WDFY4 RYR1 FANK1 ASB2 IL2RA	8.06e-06	186	113	6	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	ADGRG6 MSR1 CD163L1 FGFR1 TRIM47 IL2RA	8.31e-06	187	113	6	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DMXL2 C5AR2 RYR1 MSR1 CD163L1 TLE4	8.57e-06	188	113	6	3be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP4 LAMA4 HDAC7 NTN4 PTPRJ ADGRD1	8.57e-06	188	113	6	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	severe_influenza-CD4+_Tcm\|severe_influenza / disease group, cell group and cell class (v2)	DPP4 TMPRSS11E CNTNAP1 CD5 CD69 IL2RA	8.57e-06	188	113	6	633e5545f49b1b864b0ffa5fc9688d270690f884
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	GPC6 ADAMTSL3 SVEP1 GLP2R FGFR1 SRPX	8.57e-06	188	113	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PMP22 PAPPA2 GPC6 ADGRG6 LOXL4 FGFR1	8.57e-06	188	113	6	5a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CNTNAP1 LAMA4 GPC6 SVEP1 HEPH PLA2R1	8.83e-06	189	113	6	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-Late_pre-B\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SERHL2 IGLV1-50 IGLV1-47 IGLV1-44 IGLV1-40 CD69	8.83e-06	189	113	6	3012e67093ca7c281ee8f1b68064646961f250f9
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRPM2 CR1 WDFY4 RYR1 MSR1 CD163L1	8.83e-06	189	113	6	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PMP22 SVEP1 FGFR1 SRPX ADGRD1 SNTB2	9.10e-06	190	113	6	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRPM2 CR1 RYR1 MSR1 CD163L1 IL2RA	9.10e-06	190	113	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PMP22 SVEP1 FGFR1 SRPX ADGRD1 SNTB2	9.10e-06	190	113	6	e275de94468872e70cf305b3b450823d4c9c5e3f
Disease	Early Childhood Epilepsy, Myoclonic	PMP22 TNRC6A RAPGEF2	2.49e-06	8	106	3	C0393695
Disease	Idiopathic Myoclonic Epilepsy	PMP22 TNRC6A RAPGEF2	2.49e-06	8	106	3	C0338478
Disease	Symptomatic Myoclonic Epilepsy	PMP22 TNRC6A RAPGEF2	2.49e-06	8	106	3	C0338479
Disease	Benign Infantile Myoclonic Epilepsy	PMP22 TNRC6A RAPGEF2	2.49e-06	8	106	3	C0751120
Disease	Myoclonic Encephalopathy	PMP22 TNRC6A RAPGEF2	2.49e-06	8	106	3	C0438414
Disease	Myoclonic Absence Epilepsy	PMP22 TNRC6A RAPGEF2	2.49e-06	8	106	3	C0393703
Disease	Myoclonic Epilepsy	PMP22 TNRC6A RAPGEF2	3.73e-06	9	106	3	C0014550
Disease	Epilepsy, Myoclonic, Infantile	PMP22 TNRC6A RAPGEF2	5.31e-06	10	106	3	C0917800
Disease	Myoclonic Astatic Epilepsy	PMP22 TNRC6A RAPGEF2	7.28e-06	11	106	3	C0393702
Disease	Infantile Severe Myoclonic Epilepsy	PMP22 TNRC6A RAPGEF2	1.26e-05	13	106	3	C0751122
Disease	Polycystic kidneys, severe infantile with tuberous sclerosis	TSC2 PKD1	1.28e-05	2	106	2	C1838327
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 LRRK2 TSC2 CSMD3 RYR1 SCARB1	1.62e-05	148	106	6	C0279702
Disease	Synostotic Posterior Plagiocephaly	NELL1 IFT122 FGFR1	2.44e-05	16	106	3	C1833340
Disease	Craniosynostosis, Type 1	NELL1 IFT122 FGFR1	2.44e-05	16	106	3	C4551902
Disease	Acrocephaly	NELL1 IFT122 FGFR1	2.44e-05	16	106	3	C0030044
Disease	Trigonocephaly	NELL1 IFT122 FGFR1	2.44e-05	16	106	3	C0265535
Disease	Scaphycephaly	NELL1 IFT122 FGFR1	2.44e-05	16	106	3	C0265534
Disease	Synostotic Anterior Plagiocephaly	NELL1 IFT122 FGFR1	2.44e-05	16	106	3	C2931150
Disease	Metopic synostosis	NELL1 IFT122 FGFR1	2.44e-05	16	106	3	C1860819
Disease	Brachycephaly	NELL1 IFT122 FGFR1	2.95e-05	17	106	3	C0221356
Disease	Craniosynostosis	NELL1 IFT122 FGFR1	4.91e-05	20	106	3	C0010278
Disease	platelet-to-lymphocyte ratio	SKI HDAC7 PLA2R1 PTPRJ ICAM5 TLE4 CD69 IL2RA	5.14e-05	363	106	8	EFO_0008446
Disease	craniosynostosis (implicated_via_orthology)	SKI NELL1	7.63e-05	4	106	2	DOID:2340 (implicated_via_orthology)
Disease	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement	ADAM15 SVEP1	7.63e-05	4	106	2	EFO_0803113
Disease	cortical surface area measurement	DPP4 ANO2 ADAM15 MED13L ADAMTSL3 SVEP1 NELL1 NTN4 TLE4 PKD1 TNRC6A MTMR2 IGSF9 FGFR1 AGAP3	9.28e-05	1345	106	15	EFO_0010736
Disease	Sarcomatoid Renal Cell Carcinoma	DNHD1 LRRK2 CSMD3 RYR1 SCARB1	1.01e-04	128	106	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DNHD1 LRRK2 CSMD3 RYR1 SCARB1	1.01e-04	128	106	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DNHD1 LRRK2 CSMD3 RYR1 SCARB1	1.01e-04	128	106	5	C1266044
Disease	Papillary Renal Cell Carcinoma	DNHD1 LRRK2 CSMD3 RYR1 SCARB1	1.01e-04	128	106	5	C1306837
Disease	Renal Cell Carcinoma	DNHD1 LRRK2 CSMD3 RYR1 SCARB1	1.01e-04	128	106	5	C0007134
Disease	dietary heme iron intake measurement, type 2 diabetes mellitus	SVEP1 TNRC6A	1.90e-04	6	106	2	EFO_0008355, MONDO_0005148
Disease	X-14939 measurement	CYP4A11 CYP4A22	1.90e-04	6	106	2	EFO_0800747
Disease	blood pressure, chronic obstructive pulmonary disease	HDAC7 ADGRG6 TNRC6A	2.07e-04	32	106	3	EFO_0000341, EFO_0004325
Disease	lethal congenital contracture syndrome (is_implicated_in)	CNTNAP1 ADGRG6	2.65e-04	7	106	2	DOID:0060558 (is_implicated_in)
Disease	executive function measurement	DMXL2 THSD7B RYR1 SMYD4 ADRA1D RAPGEF2 OGA	4.27e-04	376	106	7	EFO_0009332
Disease	neuroimaging measurement	ANO2 NELL1 TLE4 PKD1 TNRC6A MTMR2 IGSF9 RAPGEF2 TRIM47 SNTB2 GABBR1 AGAP3	4.63e-04	1069	106	12	EFO_0004346
Disease	Charcot-Marie-Tooth disease	PMP22 CNTNAP1 MTMR2	4.67e-04	42	106	3	cv:C0007959
Disease	macrophage migration inhibitory factor measurement	SPP2 USP7 ADGRD1	5.01e-04	43	106	3	EFO_0008221
Disease	Holoprosencephaly sequence	FGFR1 FOXH1	5.65e-04	10	106	2	cv:C0079541
Disease	phosphatidylcholine measurement	TMPRSS11E THSD7B NELL1 FADS3 SCARB1 WDR89	5.75e-04	284	106	6	EFO_0010226
Disease	Varicose veins	ADAM15 CNTNAP1 HDAC7 ABHD16B SRPX	6.75e-04	193	106	5	HP_0002619
Disease	autosomal recessive polycystic kidney disease (biomarker_via_orthology)	CYP4A11 CYP4A22	6.88e-04	11	106	2	DOID:0110861 (biomarker_via_orthology)
Disease	birth weight, pelvic organ prolapse	LAMA4 WDR59 NTN4	7.36e-04	49	106	3	EFO_0004344, EFO_0004710
Disease	Oligodontia	LRP6 FGFR1	8.24e-04	12	106	2	C4082304
Disease	Charcot-Marie-Tooth disease type 4	PMP22 MTMR2	9.72e-04	13	106	2	cv:C4082197
Disease	glucose-dependent insulinotropic peptide measurement, glucose tolerance test	PAPPA2 GLP2R	1.13e-03	14	106	2	EFO_0004307, EFO_0008464
Disease	Hypodontia	LRP6 FGFR1	1.13e-03	14	106	2	C0020608
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	FADS3 SCARB1	1.30e-03	15	106	2	OBA_2045131
Disease	disease progression measurement	ADGRG6 TLE4 HERC1	1.39e-03	61	106	3	EFO_0008336
Disease	developmental dysplasia of the hip	ADAMTSL3 LOXL4	1.48e-03	16	106	2	EFO_1000648
Disease	Lobar Holoprosencephaly	FGFR1 FOXH1	1.48e-03	16	106	2	C0431362
Disease	Semilobar Holoprosencephaly	FGFR1 FOXH1	1.48e-03	16	106	2	C0751617
Disease	waist-hip ratio	PAPPA2 DPP4 DMXL2 WWP2 LAMA4 GPC6 ADAMTSL3 NELL1 PKD1 TNRC6A IFT122 FGFR1	1.51e-03	1226	106	12	EFO_0004343
Disease	platelet component distribution width	LRRK2 CUBN SKI HDAC7 SVEP1 OTP MAVS USP7 HERC1	1.62e-03	755	106	9	EFO_0007984
Disease	cognitive function measurement, self reported educational attainment	DMXL2 THSD7B PTPRJ TNRC6A MTMR2 OGA	1.81e-03	355	106	6	EFO_0004784, EFO_0008354
Disease	cognitive function measurement	DMXL2 CLASP1 THSD7B ADAMTSL3 CSMD3 ADRA1D CD163L1 TNRC6A MTMR2 LOXL4 FOXH1 OGA USH2A	1.90e-03	1434	106	13	EFO_0008354
Disease	susceptibility to mononucleosis measurement	HDAC7 ADRA1D MDN1	1.99e-03	69	106	3	EFO_0008403
Disease	X-24309 measurement	CYP4A11 ADRA1D	2.33e-03	20	106	2	EFO_0800872
Disease	energy expenditure measurement	THSD7B USP7	2.33e-03	20	106	2	EFO_0008005
Disease	Craniofacial Abnormalities	SKI GPC6 FGFR1 FOXI1	2.46e-03	156	106	4	C0376634
Disease	transferrin glycosylation measurement	MSR1 FOXI1	2.57e-03	21	106	2	EFO_0021537
Disease	level of Phosphatidylcholine (16:0_20:4) in blood serum	CD5 FADS3	2.57e-03	21	106	2	OBA_2045076
Disease	susceptibility to strep throat measurement	LAMA4 MSR1 IL2RA	2.62e-03	76	106	3	EFO_0008408
Disease	Disproportionate short stature	GPC6 IFT122 FGFR1	2.72e-03	77	106	3	C0878659
Disease	pyruvate measurement	PMP22 SPP2 WWP2 CR1 LOXL4	2.86e-03	268	106	5	EFO_0010117
Disease	diastolic blood pressure, systolic blood pressure	PMP22 ADAM15 GPC6 ADAMTSL3 ADRA1D LOXL4 IL2RA GABBR1	2.91e-03	670	106	8	EFO_0006335, EFO_0006336
Disease	functional brain measurement	PMP22 DPP4 LOXL4	3.25e-03	82	106	3	EFO_0007849
Disease	sphingomyelin measurement	TMPRSS11E FADS3 SCARB1 WDR89 USH2A	3.35e-03	278	106	5	EFO_0010118

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLHQRSCSVSSADQW	AGAP3	491	Q96P47
ASRWDCHSNQTAFHG	CNTNAP1	491	P78357
GSSVRICQQDHNWSG	CSMD3	2851	Q7Z407
SSRTCQLNGHWSGSQ	CSMD3	3031	Q7Z407
VWSNHGCALTRGNLT	ADGRD1	521	Q6QNK2
NCSWVHLDLGSDVAQ	ADAM15	611	Q13444
TNHRCNRGWTALHES	ASB2	231	Q96Q27
GWNTSGCVAHRDSDA	ADGRG6	816	Q86SQ4
VRQGAQWAALCDSSS	CD5	291	P06127
TSAGRWTHRACQLAH	CYP4A11	246	Q02928
SWGLAAHCTAAALAA	BTBD11	171	A6QL63
DRSWGGCRSLHSNEA	CEP72	431	Q9P209
GHSNDNRNVCLWDTL	DMXL2	2871	Q8TDJ6
GLCASLAGHSSAWQA	DNHD1	4001	Q96M86
WNLSSACGTAQASHL	ANO2	421	Q9NQ90
SCRNSGWGNNDCSHS	CD163L1	661	Q9NR16
GDCSHWTESINLTNN	DMXL1	281	Q9Y485
SHRALTCAAAAAGVW	ABHD16B	46	Q9H3Z7
WTASHIAAIRGQDAC	ANKRD42	66	Q8N9B4
ANQGSLCRDHSSWLQ	IQCC	111	Q4KMZ1
WTSAQNACSEHGATL	CD69	106	Q07108
WEHGTTISQARCAAQ	OR9Q2	86	Q8NGE9
SLAAQDHRVCSGSWD	FBXW9	231	Q5XUX1
SGAWNNATHLESCSS	PTPRJ	756	Q12913
CRQLGFEAALTWAHS	LOXL4	71	Q96JB6
LNWCNRIAHSFDSSS	MDN1	551	Q9NU22
TSLIQWLAAATGNHC	MDN1	1091	Q9NU22
HQLASCSSSDFGLWS	IFT122	106	Q9HBG6
WSQHINGASHSRRCQ	MATR3	306	P43243
NWVANGASLEDCHSN	MED13L	6	Q71F56
CTLSGNRDTLWHLFN	MAVS	46	Q7Z434
GWKDSIRHNLSSNRC	FOXH1	76	O75593
LAHCTGSWAQSVLTQ	IGLV1-50	11	A0A075B6I6
HLVGSSRSICSQGQW	GABBR1	136	Q9UBS5
RQISAGRCHSAAWTA	HERC1	4346	Q15751
RFHTNRWNLTSCGTS	FAM199X	61	Q6PEV8
HQTWLEGAEASALAC	ICAM5	676	Q9UMF0
LTHCAGSWAQSVLTQ	IGLV1-47	11	P01700
LTHCAGSWAQSVLTQ	IGLV1-44	11	P01699
VFHSSRQSGWNECAS	LRP6	881	O75581
RQSGWNECASSNGHC	LRP6	886	O75581
NSRNASIWLGCGHTD	LRRK2	2161	Q5S007
HCSDGWDRTAQLTSL	MTMR2	416	Q13614
DESSGRWNCLVARQH	DPP4	331	P27487
WTAQGNCLTINSDEH	MFSD11	116	O43934
ALRTHTCWNDSACIN	NELL1	601	Q92832
IRQWGTRACSHSEDA	MSR1	431	P21757
AIVGHADNSCVWASR	PFN3	21	P60673
LTCSSGHWDQNVSCL	PAPPA2	1446	Q9BXP8
SENQHCNWTIRATTG	CUBN	1301	O60494
ARAHLENTGCWTTNG	GLP2R	321	O95838
AAQRGHSLLSWSLTC	GPC6	531	Q9Y625
ACGSNLHQVSARSWD	KDM1B	546	Q8NB78
SSDCSRGSHNGQVWD	KDM2A	426	Q9Y2K7
ACHWALRESQGQDES	C5AR2	306	Q9P296
SSAECILSGNAAHWS	CR1	591	P17927
SSAECILSGNTAHWS	CR1	1041	P17927
CLAGNSIGLSHHSAW	FGFR1	341	P11362
TTNEHSQTCDWGNLL	FBXL3	26	Q9UKT7
TSAGRWTHRACQLAH	CYP4A22	246	Q5TCH4
HVLTGSADNSCRLWD	EIF3I	66	Q13347
RNCEDWGAGNSTLAS	CRYBG2	1326	Q8N1P7
LCTGNSSHSSWDNQC	IL2RA	66	P01589
TAAHCWGSNINVTLG	CTSG	61	P08311
SVLDHQNNEGASCDW	EME1	121	Q96AY2
GWQNSIRHNLSLNDC	FOXI1	166	Q12951
ELHSSNAARWAAGSV	HDAC7	631	Q8WUI4
AISQAQSWCLQHDLG	FADS3	171	Q9Y5Q0
LCLHGWLDNASSFDR	SERHL2	36	Q9H4I8
GNRSNCALFSTNLDW	RYR1	531	P21817
QLHANAWRVSSTCFA	OTOGL	641	Q3ZCN5
DWAARGHRSSANSAN	PKD1	2881	P98161
GDSLCSFHANDTRWA	OTP	196	Q5XKR4
TDQDSRTALHWACSA	PSMD10	36	O75832
LWSAACSRAASGDDN	LAMA4	16	Q16363
LGETWNSSLSGCCQH	OTOG	2446	Q6ZRI0
RDHAQSSATWSCSQP	NXPH3	201	O95157
RSWNDFHACASQVLS	NRN1L	71	Q496H8
LCLHGWLDNASSFDR	SERHL	36	Q9NQF3
ASWQARDLGGCTALH	FANK1	201	Q8TC84
AGHTCSSWNVVRTLQ	USH2A	4246	O75445
NAHSCCLQWNGRSFS	TRIM47	516	Q96LD4
SGCQRDAESFLWAEH	SMYD4	681	Q8IYR2
LAHCTGSWAQSVLTQ	IGLV1-40	11	P01703
CHFDVNVWEASGNRS	NTN4	341	Q9HB63
SFVQWLGCRSHSSAQ	OGA	656	O60502
GTWLISCQVNSHFRD	HEPH	341	Q9BQS7
QVQGVHARCSWSSST	SPP2	126	Q13103
TATSHWCIQFNRGSR	SLC9A5	881	Q14940
GQRAARADSHSLACW	SCARB1	471	Q8WTV0
HGSSLLICQSNKRWS	SRPX	96	P78539
LHGNSSRRCLSNGSW	SVEP1	2981	Q4LDE5
LGDCVFADSNGRWHS	PLA2R1	1206	Q13018
FADSNGRWHSTACES	PLA2R1	1211	Q13018
ALENRTCHWGFDSAN	SKI	266	P12755
HHWRASTSGLRQDCA	ADRA1D	436	P25100
DVAEVLNHCASSNWS	CLASP1	856	Q7Z460
LNHCASSNWSERKEG	CLASP1	861	Q7Z460
RGSWTSCSSGSHDNI	RAPGEF2	1246	Q9Y4G8
QASLQWDGSHRCGAT	TMPRSS11E	206	Q9UL52
WSCHTLRNELLGTAS	WWP2	86	O00308
NWACQGSHGELEASQ	nan	126	Q8N377
CSDGNIAVWDLHNQT	TLE4	596	Q04727
NSNLHACDSGASIRW	TRPM2	1461	O94759
GSQATAWHRCSSCGQ	ZNF575	206	Q86XF7
SCAGAHLSLWNVNGQ	WDFY4	3041	Q6ZS81
HGHWECSASNAVARV	IGSF9	481	Q9P2J2
ANCLATSHDGDVRIW	WDR59	161	Q6PJI9
SGSHDCSLRLWSLDN	STRN4	696	Q9NRL3
EGRECLQNSHNTSRW	WNT8A	271	Q9H1J5
DWLLAGNRTQSAHCH	TOGARAM1	611	Q9Y4F4
LQGGHAATVRSFCWN	WDR89	316	Q96FK6
VDGWTSHLSNCGESN	THSD7B	71	Q9C0I4
GRDWQSCSSEQGHRQ	RPTN	676	Q6XPR3
SSWTRILVQGCHAAA	SNTB2	426	Q13425
LLESNSSSVRWQAHC	UBR4	3416	Q5T4S7
GNGHATDLWQNCSTS	PMP22	31	Q01453
CNAESDSTSWSCHAQ	USP7	121	Q93009
FSSRTDLNHWNGAGL	TNRC6A	1891	Q8NDV7
SSCQGQLHRSVSWAD	TSC2	1281	P49815
GHCSNSAGSTNSWEL	ADAMTSL3	1061	P82987