Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopeptidase activity	ATG4A KLK15 MASP1 PRSS8 ADAMTS13 ADAM10 ADAMTS7 PRSS50 ADAMTS15 CAPN15	2.22e-04	430	117	10	GO:0004175
GeneOntologyMolecularFunction	calcium ion binding	HSPG2 MASP1 STAB2 BCAN ADAMTS13 VWCE SELENON PCDH20 STAB1 CELSR1 CELSR3 MEGF8 NOTCH4	4.48e-04	749	117	13	GO:0005509
GeneOntologyMolecularFunction	peptidase activity	ATG4A TRHDE KLK15 MASP1 PRSS8 RBP3 ADAMTS13 ADAM10 ADAMTS7 PRSS50 ADAMTS15 CAPN15	4.59e-04	654	117	12	GO:0008233
Domain	EGF_Lam	HSPG2 STAB2 NTN3 STAB1 CELSR1 CELSR3 MEGF8 MEGF11	2.48e-11	35	111	8	SM00180
Domain	Laminin_EGF	HSPG2 STAB2 NTN3 STAB1 CELSR1 CELSR3 MEGF8 MEGF11	5.08e-11	38	111	8	IPR002049
Domain	EGF_LAM_2	HSPG2 STAB2 NTN3 STAB1 CELSR1 CELSR3 MEGF8	3.93e-10	30	111	7	PS50027
Domain	EGF_LAM_1	HSPG2 STAB2 NTN3 STAB1 CELSR1 CELSR3 MEGF8	3.93e-10	30	111	7	PS01248
Domain	Laminin_EGF	HSPG2 NTN3 STAB1 CELSR1 CELSR3 MEGF8 MEGF11	1.27e-09	35	111	7	PF00053
Domain	EGF_1	HSPG2 MASP1 STAB2 NTN3 BCAN VWCE STAB1 CELSR1 CELSR3 MEGF8 MEGF11 NOTCH4	3.86e-08	255	111	12	PS00022
Domain	EGF_CA	HSPG2 MASP1 STAB2 VWCE STAB1 CELSR1 CELSR3 MEGF8 NOTCH4	4.64e-08	122	111	9	SM00179
Domain	EGF-like_CS	HSPG2 MASP1 STAB2 NTN3 BCAN VWCE STAB1 CELSR1 CELSR3 MEGF8 MEGF11 NOTCH4	4.99e-08	261	111	12	IPR013032
Domain	EGF-like_Ca-bd_dom	HSPG2 MASP1 STAB2 VWCE STAB1 CELSR1 CELSR3 MEGF8 NOTCH4	5.35e-08	124	111	9	IPR001881
Domain	EGF_2	HSPG2 MASP1 STAB2 NTN3 BCAN VWCE STAB1 CELSR1 CELSR3 MEGF8 MEGF11 NOTCH4	5.89e-08	265	111	12	PS01186
Domain	EGF_3	HSPG2 MASP1 STAB2 BCAN VWCE STAB1 CELSR1 CELSR3 MEGF8 MEGF11 NOTCH4	1.55e-07	235	111	11	PS50026
Domain	EGF-like_dom	HSPG2 MASP1 STAB2 BCAN VWCE STAB1 CELSR1 CELSR3 MEGF8 MEGF11 NOTCH4	2.77e-07	249	111	11	IPR000742
Domain	HRM	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	5.97e-07	28	111	5	PF02793
Domain	EGF	HSPG2 STAB2 BCAN VWCE STAB1 CELSR1 CELSR3 MEGF8 MEGF11 NOTCH4	1.39e-06	235	111	10	SM00181
Domain	GPS	PKD1L1 ADGRA2 CELSR1 CELSR3 ADGRF3	2.20e-06	36	111	5	PS50221
Domain	GPS	PKD1L1 ADGRA2 CELSR1 CELSR3 ADGRF3	2.54e-06	37	111	5	IPR000203
Domain	GPCR_2_extracellular_dom	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	3.77e-06	40	111	5	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	3.77e-06	40	111	5	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	3.77e-06	40	111	5	PS50227
Domain	Growth_fac_rcpt_	HSPG2 STAB2 NTN3 VWCE STAB1 CELSR1 MEGF8 NOTCH4	4.22e-06	156	111	8	IPR009030
Domain	EGF	HSPG2 STAB2 BCAN STAB1 CELSR1 CELSR3 NOTCH4	1.02e-05	126	111	7	PF00008
Domain	7tm_2	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	1.16e-05	50	111	5	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	1.16e-05	50	111	5	PS00650
Domain	GPCR_2_secretin-like	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	2.85e-05	60	111	5	IPR000832
Domain	GPCR_2-like	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	2.85e-05	60	111	5	IPR017981
Domain	ASX_HYDROXYL	MASP1 VWCE CELSR1 CELSR3 MEGF8 NOTCH4	2.91e-05	100	111	6	PS00010
Domain	G_PROTEIN_RECEP_F2_4	ADGRA2 CRHR1 CELSR1 CELSR3 ADGRF3	3.09e-05	61	111	5	PS50261
Domain	M_domain	TNRC6C TNRC6A	3.50e-05	2	111	2	PF12938
Domain	GW182_M_dom	TNRC6C TNRC6A	3.50e-05	2	111	2	IPR026805
Domain	EGF-type_Asp/Asn_hydroxyl_site	MASP1 VWCE CELSR1 CELSR3 MEGF8 NOTCH4	4.05e-05	106	111	6	IPR000152
Domain	EGF_dom	STAB2 STAB1 MEGF8	4.32e-05	12	111	3	IPR024731
Domain	EGF_3	STAB2 STAB1 MEGF8	4.32e-05	12	111	3	PF12947
Domain	GPS	ADGRA2 CELSR1 CELSR3 ADGRF3	4.78e-05	34	111	4	SM00303
Domain	GPCR_2_secretin-like_CS	ADGRA2 CRHR1 CELSR3 ADGRF3	4.78e-05	34	111	4	IPR017983
Domain	GPS	ADGRA2 CELSR1 CELSR3 ADGRF3	5.37e-05	35	111	4	PF01825
Domain	Link_dom	STAB2 BCAN STAB1	5.59e-05	13	111	3	IPR000538
Domain	Xlink	STAB2 BCAN STAB1	5.59e-05	13	111	3	PF00193
Domain	LINK_2	STAB2 BCAN STAB1	5.59e-05	13	111	3	PS50963
Domain	LINK	STAB2 BCAN STAB1	5.59e-05	13	111	3	SM00445
Domain	LINK_1	STAB2 BCAN STAB1	5.59e-05	13	111	3	PS01241
Domain	DISINTEGRIN_1	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	9.16e-05	40	111	4	PS00427
Domain	Reprolysin	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	9.16e-05	40	111	4	PF01421
Domain	ADAM_MEPRO	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	9.16e-05	40	111	4	PS50215
Domain	DISINTEGRIN_2	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	9.16e-05	40	111	4	PS50214
Domain	Peptidase_M12B	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	9.16e-05	40	111	4	IPR001590
Domain	Disintegrin_dom	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	1.01e-04	41	111	4	IPR001762
Domain	Ago_hook	TNRC6C TNRC6A	1.05e-04	3	111	2	PF10427
Domain	TNRC6_PABC-bd	TNRC6C TNRC6A	1.05e-04	3	111	2	IPR032226
Domain	Argonaute_hook_dom	TNRC6C TNRC6A	1.05e-04	3	111	2	IPR019486
Domain	TNRC6-PABC_bdg	TNRC6C TNRC6A	1.05e-04	3	111	2	PF16608
Domain	Pept_M10_metallopeptidase	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	1.22e-04	43	111	4	IPR001818
Domain	FAS1	STAB2 STAB1	2.08e-04	4	111	2	SM00554
Domain	FAS1_domain	STAB2 STAB1	2.08e-04	4	111	2	IPR000782
Domain	-	STAB2 STAB1	2.08e-04	4	111	2	2.30.180.10
Domain	FAS1	STAB2 STAB1	2.08e-04	4	111	2	PS50213
Domain	Fasciclin	STAB2 STAB1	2.08e-04	4	111	2	PF02469
Domain	Apc4_WD40_dom	WDR36 WDR53 WDR17	2.16e-04	20	111	3	IPR024977
Domain	ANAPC4_WD40	WDR36 WDR53 WDR17	2.16e-04	20	111	3	PF12894
Domain	ZINC_PROTEASE	TRHDE ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	2.96e-04	98	111	5	PS00142
Domain	ZnF_RBZ	TEX13A DZANK1 CAPN15	3.32e-04	23	111	3	SM00547
Domain	NUT	NUTM2G NUTM2F	3.46e-04	5	111	2	IPR024310
Domain	NUT_N	NUTM2G NUTM2F	3.46e-04	5	111	2	IPR024309
Domain	NUT	NUTM2G NUTM2F	3.46e-04	5	111	2	PF12881
Domain	Peptidase_M12B_ADAM-TS	ADAMTS13 ADAMTS7 ADAMTS15	3.78e-04	24	111	3	IPR013273
Domain	Znf_RanBP2	TEX13A DZANK1 CAPN15	4.27e-04	25	111	3	IPR001876
Domain	HormR	CRHR1 CELSR1 CELSR3	4.27e-04	25	111	3	SM00008
Domain	PyrdxlP-dep_de-COase	GAD2 CSAD	9.57e-04	8	111	2	IPR002129
Domain	Pyridoxal_deC	GAD2 CSAD	9.57e-04	8	111	2	PF00282
Domain	DDC_GAD_HDC_YDC	GAD2 CSAD	9.57e-04	8	111	2	PS00392
Domain	-	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	1.38e-03	81	111	4	3.40.390.10
Domain	MetalloPept_cat_dom	ADAMTS13 ADAM10 ADAMTS7 ADAMTS15	1.38e-03	81	111	4	IPR024079
Domain	LAM_G_DOMAIN	HSPG2 CELSR1 CELSR3	1.48e-03	38	111	3	PS50025
Domain	Pep_M12B_propep	ADAM10 ADAMTS7 ADAMTS15	1.60e-03	39	111	3	PF01562
Domain	Peptidase_M12B_N	ADAM10 ADAMTS7 ADAMTS15	1.60e-03	39	111	3	IPR002870
Domain	Laminin_G_2	HSPG2 CELSR1 CELSR3	1.72e-03	40	111	3	PF02210
Domain	EGF_CA	MASP1 VWCE MEGF8 NOTCH4	1.73e-03	86	111	4	PF07645
Domain	CYSTEINE_SWITCH	ADAM10 ADAMTS7 ADAMTS15	1.85e-03	41	111	3	PS00546
Domain	GFP-like	STAB2 STAB1	1.86e-03	11	111	2	IPR023413
Domain	-	STAB2 STAB1	1.86e-03	11	111	2	2.40.155.10
Domain	GAIN_dom_N	CELSR1 CELSR3	1.86e-03	11	111	2	IPR032471
Domain	GAIN	CELSR1 CELSR3	1.86e-03	11	111	2	PF16489
Domain	ConA-like_dom	HSPG2 MAMDC4 LMAN1L CELSR1 CELSR3 TRIM47	1.98e-03	219	111	6	IPR013320
Domain	LamG	HSPG2 CELSR1 CELSR3	2.27e-03	44	111	3	SM00282
Domain	-	HSPG2 LMAN1L CELSR1 CELSR3	2.48e-03	95	111	4	2.60.120.200
Domain	PROTEIN_KINASE_TYR	OBSCN LMTK3 PRAG1 AATK	2.68e-03	97	111	4	PS00109
Domain	EGF_Ca-bd_CS	MASP1 VWCE MEGF8 NOTCH4	2.68e-03	97	111	4	IPR018097
Domain	EGF_CA	MASP1 VWCE MEGF8 NOTCH4	2.88e-03	99	111	4	PS01187
Domain	Sushi	MASP1 BCAN CFHR4	3.65e-03	52	111	3	PF00084
Domain	CUB	MASP1 ADAMTS13 MEGF8	3.86e-03	53	111	3	PS01180
Domain	CCP	MASP1 BCAN CFHR4	4.07e-03	54	111	3	SM00032
Domain	SUSHI	MASP1 BCAN CFHR4	4.50e-03	56	111	3	PS50923
Domain	Peptidase_S1A	KLK15 MASP1 PRSS8 PRSS50	4.63e-03	113	111	4	IPR001314
Domain	Sushi_SCR_CCP_dom	MASP1 BCAN CFHR4	4.73e-03	57	111	3	IPR000436
Domain	CUB_dom	MASP1 ADAMTS13 MEGF8	4.73e-03	57	111	3	IPR000859
Domain	TRYPSIN_DOM	KLK15 MASP1 PRSS8 PRSS50	4.93e-03	115	111	4	PS50240
Domain	Laminin_G	HSPG2 CELSR1 CELSR3	4.97e-03	58	111	3	IPR001791
Domain	Tryp_SPc	KLK15 MASP1 PRSS8 PRSS50	5.24e-03	117	111	4	SM00020
Domain	EGF_extracell	STAB2 STAB1 MEGF11	5.47e-03	60	111	3	IPR013111
Domain	EGF_2	STAB2 STAB1 MEGF11	5.47e-03	60	111	3	PF07974
Domain	Trypsin_dom	KLK15 MASP1 PRSS8 PRSS50	5.89e-03	121	111	4	IPR001254
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 SPIRE2 LONRF1 OBSCN CEP192 TNRC6C RALGAPA2 PRAG1 ADGRA2 BIRC6 CELSR1 INTS5 ZNF276 AATK CELSR3 MEGF8 ZNRF3 ADAMTS7 CSAD ZNF408 TXNRD3 HERC2 RAI1	5.78e-12	1105	122	23	35748872
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRA2 CELSR1 CELSR3 ADGRF3	5.45e-06	33	122	4	25713288
Pubmed	Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.	GAD2 PCDH20 RAI1	9.05e-06	12	122	3	27693255
Pubmed	FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.	STAB2 STAB1	1.22e-05	2	122	2	12473645
Pubmed	Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.	STAB2 STAB1	1.22e-05	2	122	2	33008099
Pubmed	Serum TEM5 and TEM7 concentrations correlate with clinicopathologic features and poor prognosis of colorectal cancer patients.	PLXDC1 ADGRA2	1.22e-05	2	122	2	31352222
Pubmed	Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.	STAB2 STAB1	1.22e-05	2	122	2	33130055
Pubmed	Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.	STAB2 STAB1	1.22e-05	2	122	2	21427291
Pubmed	Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.	STAB2 STAB1	1.22e-05	2	122	2	21293057
Pubmed	Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.	STAB2 STAB1	1.22e-05	2	122	2	15572036
Pubmed	Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.	STAB2 STAB1	1.22e-05	2	122	2	38946049
Pubmed	Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.	STAB2 STAB1	1.22e-05	2	122	2	11829752
Pubmed	FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.	STAB2 STAB1	1.22e-05	2	122	2	12077138
Pubmed	Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.	STAB2 STAB1	1.22e-05	2	122	2	37446152
Pubmed	Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.	STAB2 STAB1	1.22e-05	2	122	2	27977633
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TRIOBP TNRC6C ADGRA2 BIRC6 STAB1 AATK ZNRF3	1.54e-05	225	122	7	12168954
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	FNDC3B MASP1 PLXDC1 RALGAPA2 ADAM10 PKHD1L1 MAMDC4 DENND2B DZANK1 MELTF DCAF17	3.15e-05	686	122	11	29987050
Pubmed	Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2.	STAB2 STAB1	3.65e-05	3	122	2	37926735
Pubmed	Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines.	WT1 SLC5A5	3.65e-05	3	122	2	15961562
Pubmed	Stabilin receptors clear LPS and control systemic inflammation.	STAB2 STAB1	3.65e-05	3	122	2	34816100
Pubmed	Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.	TNRC6C TNRC6A	3.65e-05	3	122	2	34108231
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR3	3.65e-05	3	122	2	11677057
Pubmed	Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy.	ADAMTS13 CFHR4	3.65e-05	3	122	2	31409673
Pubmed	Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.	TNRC6C TNRC6A	3.65e-05	3	122	2	16880270
Pubmed	Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family.	LMTK3 AATK	3.65e-05	3	122	2	17651901
Pubmed	Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.	TNRC6C TNRC6A	3.65e-05	3	122	2	31670606
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	TRHDE FNDC3B PKD1L1 BCAN IL17RC ADAMTS13 ITGA7 VMO1 MAMDC4 LMAN1L IZUMO2 ADGRF3 MEGF11	4.45e-05	985	122	13	12975309
Pubmed	ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.	ADAM10 NOTCH4	7.29e-05	4	122	2	27354212
Pubmed	The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.	TNRC6C TNRC6A	7.29e-05	4	122	2	23172285
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR3	7.29e-05	4	122	2	37224017
Pubmed	C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.	MASP1 CFHR4	7.29e-05	4	122	2	24279761
Pubmed	Spatial and temporal deletion reveals a latent effect of Megf8 on the left-right patterning and heart development.	WT1 MEGF8	7.29e-05	4	122	2	32203821
Pubmed	Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.	TNRC6C TNRC6A	7.29e-05	4	122	2	21063388
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR3	7.29e-05	4	122	2	11850187
Pubmed	Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.	TNRC6C TNRC6A	7.29e-05	4	122	2	20181956
Pubmed	Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.	STAB2 STAB1	7.29e-05	4	122	2	36325910
Pubmed	Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice.	STAB2 STAB1	7.29e-05	4	122	2	37357460
Pubmed	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	STAB1 ZNRF3 LY86	8.08e-05	24	122	3	20935629
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	ADGRA2 PCDH20 CELSR1 CELSR3	9.31e-05	67	122	4	21875946
Pubmed	Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis.	FNDC3B WT1 NFKBIB	1.16e-04	27	122	3	26199344
Pubmed	Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis.	STAB2 STAB1	1.21e-04	5	122	2	15907457
Pubmed	Dynamic Epicardial Contribution to Cardiac Interstitial c-Kit and Sca1 Cellular Fractions.	WT1 LY6H	1.21e-04	5	122	2	35706902
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRA2 CELSR3 ADGRF3	1.44e-04	29	122	3	15203201
Pubmed	Dystroglycan is a scaffold for extracellular axon guidance decisions.	CELSR1 CELSR3	1.81e-04	6	122	2	30758284
Pubmed	Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio.	STAB1 ZNRF3	1.81e-04	6	122	2	23670221
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS13 ADAMTS15	2.53e-04	7	122	2	11867212
Pubmed	Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.	CELSR1 CELSR3	2.53e-04	7	122	2	17937400
Pubmed	Functional dissection of the human TNRC6 (GW182-related) family of proteins.	TNRC6C TNRC6A	2.53e-04	7	122	2	19470757
Pubmed	Cell surface tumor endothelial markers are conserved in mice and humans.	PLXDC1 ADGRA2	2.53e-04	7	122	2	11559528
Pubmed	The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.	TNRC6C TNRC6A	2.53e-04	7	122	2	19383768
Pubmed	Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.	RGS12 HERC2	2.53e-04	7	122	2	36700049
Pubmed	A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.	TNRC6C TNRC6A	3.37e-04	8	122	2	24768540
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	CELSR3 MEGF8	4.32e-04	9	122	2	9693030
Pubmed	The TFEB-TGIF1 axis regulates EMT in mouse epicardial cells.	WT1 TGIF1	4.32e-04	9	122	2	36057632
Pubmed	Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver.	MASP1 ADAMTS13 CSAD HERC2	4.87e-04	103	122	4	11752456
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS13 ADAMTS7	5.39e-04	10	122	2	11167130
Pubmed	miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.	TNRC6C TNRC6A	5.39e-04	10	122	2	21984185
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SPIRE2 JPH4 MEGF11 RAI1	5.63e-04	107	122	4	11347906
Pubmed	Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.	KIF26B PCDH20	6.57e-04	11	122	2	23212062
Pubmed	Zinc transporter Slc39a8 is essential for cardiac ventricular compaction.	ADAMTS7 ADAMTS15	6.57e-04	11	122	2	29337306
Pubmed	Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.	HSPG2 NTN3	6.57e-04	11	122	2	15186747
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	CELSR1 CELSR3	6.57e-04	11	122	2	25024228
Pubmed	miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.	TNRC6C TNRC6A	6.57e-04	11	122	2	21984184
Pubmed	Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.	CELSR1 CELSR3	7.87e-04	12	122	2	11891983
Pubmed	Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety.	GAD2 CRHR1	7.87e-04	12	122	2	29786085
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS13 ADAMTS7	7.87e-04	12	122	2	25770910
Pubmed	Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.	CELSR1 CELSR3	7.87e-04	12	122	2	20631168
Pubmed	Identification and characterization of the potential promoter regions of 1031 kinds of human genes.	NDUFV1 MELTF HERC2	8.21e-04	52	122	3	11337467
Pubmed	A targeted multienzyme mechanism for selective microtubule polyglutamylation.	TTLL8 TTLL11	9.28e-04	13	122	2	17499049
Pubmed	Systems biology of the 2-cell mouse embryo.	MBTD1 TACC2	9.28e-04	13	122	2	15237213
Pubmed	Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.	WT1 CELSR1	9.28e-04	13	122	2	27597235
Pubmed	A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.	CELSR1 CELSR3	1.08e-03	14	122	2	29784671
Pubmed	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	TNRC6C TNRC6A	1.08e-03	14	122	2	19716330
Pubmed	Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.	CELSR1 CELSR3	1.08e-03	14	122	2	39225402
Pubmed	Tubulin polyglutamylase enzymes are members of the TTL domain protein family.	TTLL8 TTLL11	1.08e-03	14	122	2	15890843
Pubmed	κB-Ras proteins regulate both NF-κB-dependent inflammation and Ral-dependent proliferation.	RALGAPA2 NFKBIB	1.08e-03	14	122	2	25220458
Pubmed	GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.	ADAM10 ADGRA2 NOTCH4	1.19e-03	59	122	3	21421844
Pubmed	Selenoprotein Gene Nomenclature.	SELENON TXNRD3	1.24e-03	15	122	2	27645994
Pubmed	RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells.	TRIOBP RGS12	1.24e-03	15	122	2	36260679
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	CELSR1 CELSR3	1.24e-03	15	122	2	20473291
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	TNRC6C TNRC6A	1.24e-03	15	122	2	21981923
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HSPG2 RHOXF2 DZANK1 ZNF276 MEGF8 ZNRF3 MEGF11 CCDC107	1.40e-03	608	122	8	16713569
Pubmed	The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.	HSPG2 WT1	1.42e-03	16	122	2	21350012
Pubmed	Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress.	LMTK3 CSAD	1.42e-03	16	122	2	25113059
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	HSPG2 ITGA7	1.42e-03	16	122	2	17948866
Pubmed	Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina.	GAD2 TRIM47	1.42e-03	16	122	2	24333658
Pubmed	Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.	CELSR1 CELSR3 ZNRF3	1.50e-03	64	122	3	24431302
Pubmed	Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	ITGA7 SELENON	1.60e-03	17	122	2	20301468
Pubmed	Sall1 balances self-renewal and differentiation of renal progenitor cells.	KIF26B WT1 CFHR4	1.71e-03	67	122	3	24550112
Pubmed	REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain.	GAD2 CELSR3	1.80e-03	18	122	2	28049845
Pubmed	Assignment of 22 loci in the rat by somatic hybrid and linkage analysis.	RBP3 WT1	1.80e-03	18	122	2	8268657
Pubmed	Coronary arteries form by developmental reprogramming of venous cells.	WT1 NOTCH4	2.01e-03	19	122	2	20336138
Pubmed	Transcriptional regulatory network of SOX4 during myoblast differentiation.	RP1L1 CAPN15	2.01e-03	19	122	2	25969425
Pubmed	Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development.	WT1 LY6H	2.01e-03	19	122	2	18725519
Pubmed	Local protease signaling contributes to neural tube closure in the mouse embryo.	MASP1 PRSS8	2.22e-03	20	122	2	20152175
Pubmed	Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue-specific manner and demonstrates cell-type-dependent expression in the developing mouse CNS.	STAB2 STAB1	2.22e-03	20	122	2	15733084
Pubmed	IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.	ITGA7 ADAM10	2.22e-03	20	122	2	22687584
Pubmed	Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion.	WDR53 MELTF	2.22e-03	20	122	2	30976085
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS13 ADAMTS7 ADAMTS15	2.37e-03	75	122	3	20637190
Pubmed	Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.	KLK15 PRSS8	2.45e-03	21	122	2	19592578
Interaction	EDN3 interactions	HSPG2 PRSS8 ITGA7 SELENON MELTF CELSR1 MEGF8 ADAMTS7	1.80e-07	108	114	8	int:EDN3
Interaction	SIRPD interactions	HSPG2 SELENON ADAM10 MELTF CELSR1 MEGF8 ADAMTS7	5.72e-07	86	114	7	int:SIRPD
Interaction	TRGV3 interactions	ITGA7 ADAM10 MELTF CELSR1 MEGF8 ADAMTS7	6.64e-07	55	114	6	int:TRGV3
Interaction	TOP3B interactions	HSPG2 SPIRE2 WDR36 LONRF1 OBSCN CEP192 TNRC6C RALGAPA2 PRAG1 ADGRA2 BIRC6 CELSR1 INTS5 ZNF276 AATK CELSR3 MEGF8 ZNRF3 ADAMTS7 CSAD ZNF408 TXNRD3 HERC2 RAI1	1.97e-06	1470	114	24	int:TOP3B
Interaction	SDF2L1 interactions	HSPG2 ITGA7 SELENON ADAM10 BIRC6 MELTF CELSR1 MEGF8 ADAMTS7 LY86	1.48e-05	322	114	10	int:SDF2L1
Interaction	NXPH3 interactions	ITGA7 SELENON MELTF CELSR1 ADAMTS7	1.91e-05	58	114	5	int:NXPH3
Interaction	IL5RA interactions	HSPG2 ITGA7 SELENON ADAM10 MEGF8 ADAMTS7	7.45e-05	124	114	6	int:IL5RA
Interaction	CFC1 interactions	PRSS8 ITGA7 SELENON CELSR1 MEGF8 ADAMTS7	8.14e-05	126	114	6	int:CFC1
Interaction	NUP210P1 interactions	BIRC6 MSTO1 CELSR1 CELSR3	9.21e-05	42	114	4	int:NUP210P1
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	5.36e-05	3	77	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	5.36e-05	3	77	2	1189
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS13 ADAMTS7 ADAMTS15	6.85e-05	19	77	3	50
GeneFamily	Tubulin tyrosine ligase family	TTLL8 TTLL11	1.58e-03	14	77	2	779
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	MASP1 BCAN CFHR4	1.84e-03	57	77	3	1179
GeneFamily	Proteases, serine	MASP1 PRSS8 PRSS50	2.45e-03	63	77	3	738
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	TEX13A CAPN15	3.57e-03	21	77	2	89
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC6C TNRC6A	5.04e-03	25	77	2	775
GeneFamily	Selenoproteins	SELENON TXNRD3	5.04e-03	25	77	2	890
GeneFamily	TALE class homeoboxes and pseudogenes	MEIS3P1 TGIF1	5.45e-03	26	77	2	526
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	STAB2 STAB1	5.87e-03	27	77	2	1253
GeneFamily	Ring finger proteins	LONRF1 RNF217 ZNRF3 TRIM47 RNF208	6.36e-03	275	77	5	58
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRA2 PKHD1L1 STAB1 CELSR1 CSAD LY6H TRIM47	7.41e-07	183	122	7	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 STAB2 SELENON ADGRA2 PKHD1L1 ADAMTS7 LY6H	8.88e-07	188	122	7	26915db8863f4115b46a81982e187322e21600fd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 STAB2 SELENON ADGRA2 PKHD1L1 ADAMTS7 LY6H	8.88e-07	188	122	7	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 STAB2 SELENON ADGRA2 PKHD1L1 ADAMTS7 LY6H	8.88e-07	188	122	7	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col6a1_Fezf2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 PLXDC1 RBP3 ITGA7 SLC5A5 RP1L1	1.10e-06	122	122	6	e96aec5af0ed1d8f4cc99fde59dd6998bbc1acbd
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 STAB2 PERM1 LMTK3 VMO1 ZNF408	9.43e-06	177	122	6	8ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 STAB2 RALGAPA2 ADGRA2 STAB1 DZANK1	1.07e-05	181	122	6	a53f05c4c47465ee62e353716456bd09ab464b23
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 STAB2 RALGAPA2 ADGRA2 STAB1 DZANK1	1.14e-05	183	122	6	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 STAB2 RALGAPA2 ADGRA2 STAB1 DZANK1	1.14e-05	183	122	6	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE STAB2 KIF26B OBSCN PKHD1L1 MELTF	1.18e-05	184	122	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE STAB2 KIF26B OBSCN PKHD1L1 MELTF	1.18e-05	184	122	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE STAB2 KIF26B OBSCN PKHD1L1 MELTF	1.18e-05	184	122	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM10 ADGRA2 PKHD1L1 STAB1 CELSR1 TRIM47	1.29e-05	187	122	6	d9943e65eedab73d141eae524e2411653a751705
ToppCell	facs-Heart-LA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM10 ADGRA2 PKHD1L1 STAB1 CELSR1 TRIM47	1.29e-05	187	122	6	7b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWCE ADGRA2 PKHD1L1 STAB1 TXNRD3 TRIM47	1.37e-05	189	122	6	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWCE ADGRA2 PKHD1L1 STAB1 TXNRD3 TRIM47	1.37e-05	189	122	6	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRA2 PKHD1L1 STAB1 CELSR1 CSAD LY6H	1.41e-05	190	122	6	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCAN RALGAPA2 ADGRA2 PKHD1L1 STAB1 TRIM47	1.59e-05	194	122	6	c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell	ASK428-Endothelial\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	HSPG2 STAB2 ADGRA2 PKHD1L1 STAB1 NOTCH4	1.78e-05	198	122	6	d69d0ff115298596173a4278897a65007a71f5df
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRHDE MASP1 ETV2 SLC5A5 IZUMO2	2.84e-05	129	122	5	6bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLK15 KRT84 CRHR1 RP1L1 PRSS50	4.06e-05	139	122	5	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLK15 KRT84 CRHR1 RP1L1 PRSS50	4.06e-05	139	122	5	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRHDE GAD2 MASP1 KIF26B SLC5A5	5.30e-05	147	122	5	50e86860a94be103092c40e39a172eac92372f0d
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D175\|Adult / Lineage, Cell type, age group and donor	ATG4A DENND2B INTS5 FAM86C1P SLC22A31	5.48e-05	148	122	5	012845b10850bbc67814da247ee5a69f6d631eaa
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 C10orf95 C10orf90 RNF208 NOTCH4	5.84e-05	150	122	5	322aa0c3fc159a4b2897daac881dfc744b24ffc4
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MASP1 WDR36 CEP192 TNRC6C AATK	6.21e-05	152	122	5	0652ee3443e6fbb679d2c4f326239ae7c803f924
Disease	Malignant neoplasm of breast	KLK15 FNDC3B OBSCN WT1 TACC2 ADAM10 MAMDC4 PCDH20 CRHR1 WDR53 SLC5A5 HERC2 NOTCH4	1.40e-04	1074	107	13	C0006142
Disease	axial length measurement	RBP3 ADGRA2 MELTF ZNRF3	1.80e-04	77	107	4	EFO_0005318
Disease	cortical thickness	HSPG2 SPIRE2 TRIOBP TACC2 ADAM10 ADGRA2 CRHR1 STAB1 LMAN1L VPS13D CELSR1 ADAMTS7 TNRC6A	1.98e-04	1113	107	13	EFO_0004840
Disease	hepatocyte growth factor activator measurement	DOK7 RGS12	2.70e-04	7	107	2	EFO_0008152
Disease	S-6-hydroxywarfarin to S-warfarin ratio measurement	KIF26B TACC2 BIRC6 WDR53	3.02e-04	88	107	4	EFO_0803332
Disease	corneal topography	FNDC3B PKD1L1 RBP3 ADAMTS7	6.79e-04	109	107	4	EFO_0004345
Disease	Secondary Open Angle Glaucoma	FNDC3B WDR36	8.40e-04	12	107	2	C0271148
Disease	Congenital muscular dystrophy	ITGA7 SELENON	8.40e-04	12	107	2	cv:C0699743
Disease	Glaucoma, Open-Angle	FNDC3B WDR36	8.40e-04	12	107	2	C0017612
Disease	Glaucoma, Primary Open Angle	FNDC3B WDR36	9.90e-04	13	107	2	C0339573
Disease	neuroticism measurement, cognitive function measurement	TRHDE HTR6 BIRC6 STAB1 AATK TTLL11 TNRC6A RAI1	1.08e-03	566	107	8	EFO_0007660, EFO_0008354
Disease	Congenital Fiber Type Disproportion	ITGA7 SELENON	1.92e-03	18	107	2	C0546264
Disease	cerebellum white matter volume change measurement, age at assessment	TRHDE ADAMTS7	2.37e-03	20	107	2	EFO_0008007, EFO_0021498
Disease	citrulline measurement	KIF26B RP1L1	2.37e-03	20	107	2	EFO_0009777
Disease	worry measurement	RGS12 CRHR1 STAB1 NOTCH4	2.43e-03	154	107	4	EFO_0009589
Disease	complement factor H-like 1 protein measurement	KLK15 RNF217	2.87e-03	22	107	2	EFO_0600092

Protein segments in the cluster

Peptide	Gene	Start	Entry
HAGGDSWQPEAGGVA	TRHDE	101	Q9UKU6
EDSDCGFSPGGQGLW	MAMDC4	816	Q6UXC1
AGTPGAESEAGACWL	CCDC185	46	Q8N715
CRWGGTTGTVGEAPF	DCAF17	256	Q5H9S7
SAPGGSGWVAAALCV	HTR6	21	P50406
GADGVWGPVHSSCTD	ADGRF3	466	Q8IZF5
GTGPSSDAGWGCMLR	ATG4A	66	Q8WYN0
LCWLAGVHSNGPGSS	BIRC6	1356	Q9NR09
GCKESGCSWHGGPDG	ALDH16A1	466	Q8IZ83
HGGGWCVGSAALSGY	AADAC	111	P22760
EGPGEAGGWTSEGCQ	ADGRA2	716	Q96PE1
AWVGAPSGSSGGICE	ADAM10	331	O14672
LNFSEPSSCGGAGAW	APCDD1L	371	Q8NCL9
PSSCGGAGAWSMGTE	APCDD1L	376	Q8NCL9
WLCSLPHAVGGGDGD	CCDC144NL	161	Q6NUI1
GGTGGWSARGCELLS	CELSR1	2421	Q9NYQ6
SGSEWAASEGCPSLG	DENND2B	191	P78524
GMSCPPGWGHLDATS	ADAMTS13	861	Q76LX8
GSWGPCSASCGSGLQ	ADAMTS15	846	Q8TE58
GEWQLCSSSCGPGGL	ADAMTS7	886	Q9UKP4
KAGWGSPCHLSGESV	RAI1	911	Q7Z5J4
SDWHLEGSGGNDAPG	HSPG2	4186	P98160
SPSAGCRGAPQGSGW	CAPN15	266	O75808
GGLDHCSPGWLADGS	BCAN	296	Q96GW7
ELSCWGGGWGLPSVH	MTX3	6	Q5HYI7
ALCVEGGGGTAWSGS	PCDH20	151	Q8N6Y1
GSGDSENPGTARAWC	GAD2	16	Q05329
EPGWGGPDCSSGCDS	MEGF11	121	A6BM72
SWEPLVCHTGPGAEG	PTCRA	101	Q6ISU1
VSCWSGPGFRGLGSF	KRT84	36	Q9NSB2
ACGSDWIPAGSSGSK	NCDN	291	Q9UBB6
GGGGKAWPTHVVCSD	LY86	21	O95711
CGWEGSGFPGAQPVS	RNGTT	261	O60942
GSDIHPVGWCAASGK	MBTD1	226	Q05BQ5
AATGEVYSWGCGDGG	HERC2	511	O95714
GDGASQGLGSCHWDF	LMAN1L	166	Q9HAT1
HGLGWSAAPVAGADG	LONRF1	101	Q17RB8
GSCGGWLPAGSTSGL	FAM86C1P	101	Q9NVL1
VGISTWGGQHCGCPA	FAM182A	76	Q5T1J6
GGGSSPGSDRGVWCE	KIF26B	116	Q2KJY2
TGPGAQGEYSGCWAH	JPH4	31	Q96JJ6
GDAVAGWGGHPALGC	LMTK3	686	Q96Q04
WCDSGLGSLGPDAAA	NFKBIB	16	Q15653
SGWGLVSHNEPGTAG	KLK15	141	Q9H2R5
FGGATPWTPLSACGE	MSTO1	391	Q9BUK6
SGPLGGGNCSLWVGE	MEGF8	1041	Q7Z7M0
PLGSLGGWTGHTFGC	NHLRC4	36	P0CG21
GGWTGHTFGCPAGIC	NHLRC4	41	P0CG21
DCSIIAGGSLTGWHP	RALGAPA2	911	Q2PPJ7
NGAAGAGHSPWALAG	LY6H	111	O94772
GPGLAGWSHLCGAAL	FAM182B	96	Q5T319
LSWAAPMSDGGGGLC	OBSCN	4541	Q5VST9
GSSALWVPAGDAACG	NTN3	501	O00634
PSHSLGWEGGTTAEG	CCDC107	261	Q8WV48
LTWPSCGFFGLGGAA	C18orf15	81	Q96N68
GKGPCVWDTFTHQGG	GBA3	26	Q9H227
DSGHSLLCGWSPGGK	C21orf58	26	P58505
GCVLVGWESPDSSGA	FNDC3B	781	Q53EP0
PGCTHWGDQADGALE	CRHR1	146	P34998
WSSGDGIFCPGGSIS	CSAD	141	Q9Y600
GSIVCGEDGWSHFPT	CFHR4	436	Q92496
GQPFCGGSLLGSSWI	MASP1	471	P48740
CGIEPWDSGVTSGLG	CEP192	1356	Q8TEP8
GGHWAGISPLRLCGS	ITGA7	406	Q13683
GQTSAGCPSGWLGTR	DOK7	436	Q18PE1
GGGHQGWDPGLAATT	CELSR3	36	Q9NYQ7
AEGDGGLCGSRSSWV	DZANK1	556	Q9NVP4
CSVGPDGDTYWGSGL	ETV2	156	O00321
WGSGLGGEPRTDCTI	ETV2	166	O00321
GSCGGWLPAGSTSGL	FAM86C2P	101	A6NEL3
SGAAAGPTWNLVCGD	SLC22A31	111	A6NKX4
SGLGAPGGWGCLQCD	IZUMO2	11	Q6UXV1
ATGAHGGPGAWEAVA	PERM1	531	Q5SV97
SWGLHLCSCSPPGGG	PKD1L1	36	Q8TDX9
SEWLQDGVSGPGAHG	IL17RC	661	Q8NAC3
GWGHPRGGDVCSSDS	MEIS3P1	6	A6NDR6
ELGHQGPSEGTGDWS	MEA1	36	Q16626
VGGTQACEGGWSHGL	NUTM2F	141	A1L443
VGGTQACEGGWSHGL	NUTM2G	141	Q5VZR2
ACLGALWPHRGASGA	TRIM47	31	Q96LD4
GHWNAPCLGGKGSSE	TNRC6C	1631	Q9HCJ0
GGQTSWDSGCLAPPS	PLEKHN1	346	Q494U1
CHAGFGSPAGWDVPV	MELTF	476	P08582
WDPVSAGGHAEGCPS	AATK	696	Q6ZMQ8
GHTICALGDGAAWPV	NDUFV1	421	P49821
TWESGCVGSDLGPAA	PSD4	371	Q8NDX1
CSDGEELQGPGLSWG	VMO1	146	Q7Z5L0
SLSWAPGGLNCIAGG	WDR17	441	Q8IZU2
ASAEPSGGGCGSDWG	RNF217	46	Q8TC41
GGTECGECWGAPILS	INTS5	791	Q6P9B9
GDSGGPLSCPVEGLW	PRSS8	236	Q16651
VGWTGPECEAELGGC	NOTCH4	681	Q99466
CSGPGGNWDGGDCSL	NOTCH4	1191	Q99466
SGTPTAVGWGAEGAC	TRIOBP	1531	Q9H2D6
GTGACPWSGSFPLEN	C10orf90	356	Q96M02
AWSGACGAGPTAATA	C10orf95	226	Q9H7T3
HCSGSGGGGSDSFPW	TGIF1	16	Q15583
CSGGSLVADWGGGAA	TTLL11	61	Q8NHH1
TTGTTWDGGPGVCFL	TTLL8	771	A6PVC2
SSSRHGPGGSAWDGV	RGS12	446	O14924
GGSQTWEGSGVLPCV	RBP3	291	P10745
APSGGQWGAEPEGSC	RNF208	221	Q9H0X6
SHEGSSEWGGRPQGC	RP1L1	541	Q8IWN7
GWAGDAGSRTCSPAP	RP1L1	761	Q8IWN7
EGAGSWTPCVGHDGG	SLC5A5	621	Q92911
SCGGAAAGAGRPEPW	SPIRE2	6	Q8WWL2
GEGWAARGFGSLPCI	SPIRE2	361	Q8WWL2
DLGWNPSGEGCTQGL	ZNF408	26	Q9H9D4
LLWGALDDQSCUGSG	SELENON	451	Q9NZV5
LSGFGSGCCPGWAPS	VWCE	46	Q96DN2
WGPVGSCGDAGEDGA	ZNF276	51	Q8N554
GGGCALPVSGAAQWA	WT1	21	P19544
EGLGGSGSCFCDEGW	STAB1	2031	Q9NY15
GSGQCLCETGWTGPS	STAB2	2026	Q8WWQ8
GGEHPCAGRLEVTWG	SCART1	236	Q4G0T1
GASEAADGCSPLWGL	TACC2	1016	O95359
PGHLWEGDLEGTSGS	RHOXF2	86	Q9BQY4
GGRSGICWPTFASAH	PKHD1L1	3571	Q86WI1
GDLTAWGEDGTPLGH	WDR53	31	Q7Z5U6
ACSKGSPGWRTAGQG	nan	16	Q6ZWC4
HWLPAAGLAGNRGGC	PRAG1	891	Q86YV5
WLSCGLQGTGGGHLE	nan	71	Q0VFX4
GAGWPGLATAGGVCT	TEX13A	156	Q9BXU3
GLPSDCQGTHSLGSW	ZNRF3	841	Q9ULT6
CQGTHSLGSWGGTRG	ZNRF3	846	Q9ULT6
SPQGTSWGLGGTCVN	TXNRD3	191	Q86VQ6
GHDEGPGSGWAAKGT	PLXDC1	26	Q8IUK5
LLRSAGCWGAGEAPG	PRSS50	31	Q9UI38
GCWGAGEAPGALSTA	PRSS50	36	Q9UI38
AGWLCRETGAAPGSA	nan	41	Q8N6K4
SGTNCGDLHGTSLWG	TNRC6A	1906	Q8NDV7
AAGSPCGHIGLWDLE	WDR36	306	Q8NI36
GMPGWCQGFSLDGGS	VPS13D	3346	Q5THJ4