Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled photoreceptor activity

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

5.79e-0715934GO:0008020
GeneOntologyMolecularFunctionphotoreceptor activity

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

1.00e-0617934GO:0009881
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

SOX1 FOXO1 SOX10 FLI1 HOXB7 OTX1 OTX2 NFKB2 POU1F1 POU3F2 EBF1 RFX4 MEF2C

1.93e-065609313GO:0001228
GeneOntologyMolecularFunctionneuregulin binding

ERBB4 ITGA6 ITGB4

1.94e-066933GO:0038132
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

SOX1 FOXO1 SOX10 FLI1 HOXB7 OTX1 OTX2 NFKB2 POU1F1 POU3F2 EBF1 RFX4 MEF2C

2.17e-065669313GO:0001216
GeneOntologyMolecularFunctionhistone phosphatase activity

EYA1 EYA2

6.42e-053932GO:0140789
GeneOntologyMolecularFunctionhistone H2AXY142 phosphatase activity

EYA1 EYA2

6.42e-053932GO:0140793
GeneOntologyMolecularFunctionchromatin binding

FOXO1 SOX10 FLI1 ARID1B DDX17 SUPT5H ANKRD17 POU1F1 PAX3 PHF8 ARID1A MEF2C

1.61e-047399312GO:0003682
GeneOntologyMolecularFunctionHMG box domain binding

POU3F2 PAX3 MEF2C

1.62e-0423933GO:0071837
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

SOX1 FOXO1 SOX10 FLI1 HOXB7 OTX1 OTX2 NFKB2 ZBTB8A POU1F1 POU3F2 DMRTA1 PAX3 EBF1 RFX4 MEF2C

1.88e-0412449316GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

SOX1 FOXO1 SOX10 FLI1 HOXB7 OTX1 OTX2 NFKB2 ZBTB8A POU1F1 POU3F2 DMRTA1 PAX3 EBF1 RFX4 MEF2C

2.40e-0412719316GO:0000987
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A7 SLC12A5

7.56e-049932GO:0015379
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

SOX1 FOXO1 SOX10 FLI1 HOXB7 OTX1 OTX2 NFKB2 ZBTB8A POU1F1 POU3F2 DMRTA1 PAX3 EBF1 RFX4 MEF2C

7.63e-0414129316GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

SOX1 FOXO1 SOX10 FLI1 HOXB7 OTX1 OTX2 NFKB2 ZBTB8A POU1F1 POU3F2 DMRTA1 PAX3 EBF1 RFX4 MEF2C

1.08e-0314599316GO:0000977
GeneOntologyMolecularFunctionammonium channel activity

SLC12A7 SLC12A5

1.37e-0312932GO:0008519
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

ITGA6 ITGB4

1.62e-0313932GO:0031994
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SOX1 FOXO1 SOX10 FLI1 HOXB7 OTX1 OTX2 DDX17 SUPT5H NFKB2 ITGA6 POU1F1 POU3F2 PAX3 EBF1 EYA1 TLR9 PHF8 AP3B1 RFX4 MEF2C

3.36e-0713908921GO:0045944
GeneOntologyBiologicalProcessanimal organ morphogenesis

SOX1 FLI1 FAT4 HOXB7 ERBB4 OTX1 EYA4 OTX2 ACTA1 ACTA2 ACTC1 ITGA6 BBS2 PAX3 EYA1 SLC44A4 ARID1A AP3B1 ITGB4 MEF2C

3.49e-0712698920GO:0009887
GeneOntologyBiologicalProcessmesenchyme migration

ACTA1 ACTA2 ACTC1

7.72e-075893GO:0090131
GeneOntologyBiologicalProcessforebrain development

SOX1 FAT4 ERBB4 OTX1 OTX2 GART BBS2 POU1F1 POU3F2 ARID1A MGARP RFX4

1.25e-064898912GO:0030900
GeneOntologyBiologicalProcessinner ear development

FAT4 OTX1 EYA4 OTX2 LRP10 OTOGL EYA1 SLC44A4

1.38e-05253898GO:0048839
GeneOntologyBiologicalProcesscell fate commitment

SOX1 ERBB4 OTX2 POU1F1 POU3F2 PAX3 EYA1 EYA2 MEF2C

1.54e-05338899GO:0045165
GeneOntologyBiologicalProcesscell fate specification

SOX1 OTX2 POU1F1 POU3F2 EYA1 EYA2

1.54e-05123896GO:0001708
GeneOntologyBiologicalProcessneuron fate specification

SOX1 OTX2 POU3F2 EYA1

3.20e-0542894GO:0048665
GeneOntologyBiologicalProcessear development

FAT4 OTX1 EYA4 OTX2 LRP10 OTOGL EYA1 SLC44A4

3.23e-05285898GO:0043583
GeneOntologyBiologicalProcessneuron fate commitment

SOX1 OTX2 POU3F2 PAX3 EYA1

4.64e-0591895GO:0048663
GeneOntologyBiologicalProcessembryonic morphogenesis

HOXB7 OTX1 EYA4 COL12A1 OTX2 PAX3 EYA1 EYA2 SLC44A4 ARID1A MEF2C YTHDF2

5.51e-057138912GO:0048598
GeneOntologyBiologicalProcessbrain development

SOX1 FAT4 ERBB4 OTX1 OTX2 GART BBS2 POU1F1 POU3F2 PHF8 ARID1A MGARP RFX4

7.78e-058598913GO:0007420
GeneOntologyBiologicalProcessphototransduction

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

8.07e-0553894GO:0007602
GeneOntologyBiologicalProcesstissue morphogenesis

SOX10 FAT4 HOXB7 ERBB4 ACTA1 ACTA2 ACTC1 PAX3 EYA1 EYA2 ARID1A MEF2C

8.92e-057508912GO:0048729
GeneOntologyBiologicalProcesstelencephalon development

FAT4 ERBB4 OTX2 GART BBS2 POU3F2 MGARP RFX4

9.43e-05332898GO:0021537
GeneOntologyBiologicalProcessdetection of visible light

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

1.07e-0457894GO:0009584
GeneOntologyBiologicalProcessembryonic organ morphogenesis

HOXB7 OTX1 EYA4 OTX2 EYA1 SLC44A4 ARID1A MEF2C

1.38e-04351898GO:0048562
GeneOntologyBiologicalProcesshead development

SOX1 FAT4 ERBB4 OTX1 OTX2 GART BBS2 POU1F1 POU3F2 PHF8 ARID1A MGARP RFX4

1.53e-049198913GO:0060322
GeneOntologyBiologicalProcesscentral nervous system development

SOX1 SOX10 FAT4 ERBB4 OTX1 OTX2 GART BBS2 POU1F1 POU3F2 PAX3 PHF8 ARID1A MGARP RFX4

1.73e-0411978915GO:0007417
GeneOntologyBiologicalProcessmesenchyme development

SOX10 ERBB4 DDX17 ACTA1 ACTA2 ACTC1 PAX3 MEF2C

2.06e-04372898GO:0060485
GeneOntologyBiologicalProcesspigmentation

SOX10 BBS2 PAX3 AP3B1 MEF2C

2.08e-04125895GO:0043473
GeneOntologyBiologicalProcesssensory perception of sound

EYA4 LOXHD1 OTOF OTOGL PAX3 EYA1

2.18e-04198896GO:0007605
GeneOntologyBiologicalProcessdiencephalon morphogenesis

OTX1 OTX2

2.73e-046892GO:0048852
GeneOntologyBiologicalProcessdetection of light stimulus

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

3.45e-0477894GO:0009583
GeneOntologyBiologicalProcessskeletal muscle thin filament assembly

ACTA1 ACTC1

3.81e-047892GO:0030240
GeneOntologyBiologicalProcesspositive regulation of DNA repair

ARID1B EYA4 EYA1 EYA2 ARID1A

3.88e-04143895GO:0045739
GeneOntologyBiologicalProcesscerebral cortex development

FAT4 GART BBS2 POU3F2 MGARP

4.41e-04147895GO:0021987
GeneOntologyBiologicalProcesspattern specification process

SOX1 HOXB7 ERBB4 OTX1 OTX2 PAX3 EYA1 RFX4 MEF2C

4.43e-04526899GO:0007389
GeneOntologyBiologicalProcessvisual perception

OPN1MW2 OPN1MW3 EYA4 OPN1LW BBS2 OPN1MW

4.84e-04230896GO:0007601
GeneOntologyBiologicalProcessacetate ester metabolic process

SLC44A4 COLQ

5.07e-048892GO:1900619
GeneOntologyBiologicalProcessacetylcholine metabolic process

SLC44A4 COLQ

5.07e-048892GO:0008291
GeneOntologyBiologicalProcesssensory perception of light stimulus

OPN1MW2 OPN1MW3 EYA4 OPN1LW BBS2 OPN1MW

5.18e-04233896GO:0050953
GeneOntologyBiologicalProcessear morphogenesis

OTX1 EYA4 OTX2 EYA1 SLC44A4

5.45e-04154895GO:0042471
GeneOntologyBiologicalProcesspositive regulation of developmental growth

ADCY10 ERBB4 BBS2 POU1F1 POU3F2 MEF2C

5.80e-04238896GO:0048639
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

EYA4 LOXHD1 OTOF OTOGL PAX3 EYA1

5.80e-04238896GO:0050954
GeneOntologyBiologicalProcessdiencephalon development

OTX1 OTX2 POU1F1 POU3F2

6.24e-0490894GO:0021536
GeneOntologyBiologicalProcessnephron morphogenesis

FAT4 HOXB7 ERBB4 EYA1

6.50e-0491894GO:0072028
GeneOntologyBiologicalProcesspositive regulation of growth

ADCY10 ERBB4 BBS2 POU1F1 POU3F2 SLC44A4 MEF2C

6.62e-04339897GO:0045927
GeneOntologyBiologicalProcesssensory perception

OPN1MW2 OPN1MW3 OR5M10 EYA4 LOXHD1 OTOF OTOGL OPN1LW OR1F12P BBS2 PAX3 EYA1 OPN1MW

6.69e-0410728913GO:0007600
GeneOntologyBiologicalProcessmuscle tissue development

ERBB4 DDX17 ACTA1 ACTC1 PAX3 EYA1 EYA2 ARID1A MEF2C

6.77e-04558899GO:0060537
GeneOntologyBiologicalProcessnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

EYA4 EYA1 EYA2

6.84e-0440893GO:2001240
GeneOntologyBiologicalProcessnegative regulation of signal transduction in absence of ligand

EYA4 EYA1 EYA2

6.84e-0440893GO:1901099
GeneOntologyBiologicalProcessrenal tubule morphogenesis

FAT4 HOXB7 EYA1 MEF2C

7.06e-0493894GO:0061333
GeneOntologyBiologicalProcesssensory organ morphogenesis

SOX1 OTX1 EYA4 OTX2 EYA1 SLC44A4 ARID1A

7.09e-04343897GO:0090596
GeneOntologyBiologicalProcessstriated muscle tissue development

ERBB4 ACTC1 PAX3 EYA1 EYA2 ARID1A MEF2C

7.85e-04349897GO:0014706
GeneOntologyCellularComponentphotoreceptor disc membrane

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

4.88e-0626924GO:0097381
GeneOntologyCellularComponentchromatin

SOX1 FOXO1 SOX10 FLI1 HOXB7 ARID1B OTX1 OTX2 NFKB2 ANKRD17 POU1F1 POU3F2 DMRTA1 PAX3 EBF1 ARID1A RFX4 MEF2C

6.89e-0514809218GO:0000785
GeneOntologyCellularComponentactin-based cell projection

EPS8 LOXHD1 ACTA1 ACTA2 ACTC1 ITGA6 BBS2

2.28e-04278927GO:0098858
GeneOntologyCellularComponentbasal part of cell

ADCY10 ERBB4 CLCA2 OTOF ITGA6 TLR9 ITGB4 SLC29A4

2.63e-04378928GO:0045178
GeneOntologyCellularComponentbBAF complex

ARID1B ARID1A

8.43e-0410922GO:0140092
GeneOntologyCellularComponentbasal plasma membrane

ERBB4 CLCA2 OTOF ITGA6 TLR9 ITGB4 SLC29A4

9.62e-04354927GO:0009925
GeneOntologyCellularComponenthemidesmosome

ITGA6 ITGB4

1.03e-0311922GO:0030056
GeneOntologyCellularComponentphotoreceptor outer segment

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

1.47e-03111924GO:0001750
GeneOntologyCellularComponentnpBAF complex

ARID1B ARID1A

1.68e-0314922GO:0071564
GeneOntologyCellularComponentbrahma complex

ARID1B ARID1A

1.68e-0314922GO:0035060
GeneOntologyCellularComponentbasement membrane

ACTA2 ITGA6 COLQ ITGB4

2.08e-03122924GO:0005604
GeneOntologyCellularComponentfilopodium

ACTA1 ACTA2 ACTC1 ITGA6

2.14e-03123924GO:0030175
GeneOntologyCellularComponentnBAF complex

ARID1B ARID1A

2.21e-0316922GO:0071565
MousePhenoabnormal ear morphology

SOX10 EPS8 FAT4 OTX1 EYA4 OTX2 LOXHD1 OTOF POU1F1 PAX3 EYA1 AP3B1 SLC12A7

2.07e-064707913MP:0002102
MousePhenoabnormal inner ear morphology

SOX10 EPS8 FAT4 OTX1 LOXHD1 OTOF POU1F1 PAX3 EYA1 SLC12A7

7.58e-063037910MP:0000026
MousePhenoabnormal cochlea morphology

SOX10 EPS8 FAT4 LOXHD1 OTOF POU1F1 PAX3 EYA1 SLC12A7

1.05e-05248799MP:0000031
MousePhenoabnormal membranous labyrinth morphology

EPS8 FAT4 OTX1 LOXHD1 OTOF POU1F1 PAX3 EYA1 SLC12A7

1.63e-05262799MP:0000035
MousePhenoabnormal forebrain morphology

SOX1 SOX10 ARID1B OTX1 ATP6V0A1 OTX2 PDHB ITGA6 BBS2 POU1F1 POU3F2 PAX3 EBF1 STAM PHF8 ARID1A AP3B1 RFX4

2.25e-0510727918MP:0000783
MousePhenoabnormal telencephalon morphology

SOX1 SOX10 ARID1B OTX1 ATP6V0A1 OTX2 ITGA6 BBS2 POU1F1 PAX3 EBF1 STAM PHF8 AP3B1 RFX4

4.17e-058127915MP:0000787
MousePhenoabnormal neuron number

SOX10 ARID1B ATP6V0A1 OTX2 KIDINS220 BBS2 POU1F1 POU3F2 EYA1 STAM SLC12A7

4.82e-054567911MP:0008946
MousePhenodecreased neuron number

SOX10 ARID1B ATP6V0A1 OTX2 KIDINS220 BBS2 POU1F1 EYA1 STAM SLC12A7

4.85e-053767910MP:0008948
MousePhenodecreased tail pigmentation

SOX10 PAX3 AP3B1

1.33e-0418793MP:0011277
MousePhenohearing/vestibular/ear phenotype

SOX10 EPS8 FAT4 OTX1 EYA4 OTX2 LOXHD1 OTOF OTOGL POU1F1 PAX3 EYA1 EYA2 AP3B1 SLC12A7

1.42e-049057915MP:0005377
MousePhenoabnormal cochlear hair cell morphology

EPS8 FAT4 LOXHD1 OTOF POU1F1 EYA1 SLC12A7

1.43e-04202797MP:0002622
MousePhenoabnormal vision

OPN1MW2 OPN1MW3 OTX2 OPN1LW AP3B1

1.45e-0489795MP:0002090
MousePhenoperinatal lethality

SOX10 FAT4 ARID1B OTX1 EYA4 COL12A1 OTX2 LPP ITGA6 PAX3 EYA1 ARID1A AP3B1 RFX4 ITGB4 MEF2C SLC12A5

1.55e-0411307917MP:0002081
MousePhenoabnormal cochlear hair cell stereociliary bundle morphology

EPS8 FAT4 OTOF POU1F1 EYA1

1.61e-0491795MP:0004521
MousePhenoperinatal lethality, complete penetrance

SOX10 FAT4 ARID1B OTX1 EYA4 OTX2 ITGA6 PAX3 EYA1 ARID1A RFX4 ITGB4 SLC12A5

1.63e-047127913MP:0011089
MousePhenoabnormal cochlear sensory epithelium morphology

EPS8 FAT4 LOXHD1 OTOF POU1F1 EYA1 SLC12A7

1.66e-04207797MP:0003308
MousePhenoabnormal organ of Corti morphology

EPS8 FAT4 LOXHD1 OTOF POU1F1 EYA1 SLC12A7

1.76e-04209797MP:0000042
MousePhenolethality during fetal growth through weaning, complete penetrance

SOX10 FAT4 ARID1B OTX1 EYA4 ATP6V0A1 OTX2 KIDINS220 ACTA1 ACTC1 ITGA6 POU3F2 PAX3 EYA1 ARID1A RFX4 ITGB4 SLC12A5

2.01e-0412697918MP:0011111
MousePhenoabnormal hair cell morphology

EPS8 FAT4 LOXHD1 OTOF POU1F1 EYA1 SLC12A7

2.04e-04214797MP:0000045
MousePhenoabnormal brain ventricle morphology

ARID1B OTX1 OTX2 KIDINS220 BBS2 PAX3 RFX4 SLC29A4

2.06e-04286798MP:0000822
MousePhenoabnormal vestibulocochlear nerve morphology

ERBB4 OTOF EYA1

2.84e-0423793MP:0001072
MousePhenoabsent organ of Corti

EYA1 SLC12A7

3.12e-045792MP:0000044
MousePhenoabnormal mechanoreceptor morphology

EPS8 FAT4 LOXHD1 OTOF POU1F1 EYA1 SLC12A7

3.24e-04231797MP:0000972
MousePhenoabnormal basal ganglion morphology

SOX1 BBS2 EBF1 PHF8 RFX4

3.29e-04106795MP:0006007
MousePhenoabnormal cochlear labyrinth morphology

EPS8 FAT4 LOXHD1 OTOF POU1F1 EYA1 SLC12A7

3.60e-04235797MP:0004426
MousePhenoabnormal scala media morphology

EPS8 FAT4 LOXHD1 OTOF POU1F1 EYA1 SLC12A7

3.60e-04235797MP:0003169
MousePhenoabnormal cranial ganglia morphology

SOX10 ERBB4 OTX2 LOXHD1 EYA1 SLC12A7

4.61e-04175796MP:0001081
MousePhenoabnormal ultimobranchial body morphology

PAX3 EYA1

4.66e-046792MP:0003955
MousePhenoshort endolymphatic duct

PAX3 EYA1

4.66e-046792MP:0008065
MousePhenodeafness

LOXHD1 OTOF POU1F1 EYA1 SLC12A7

4.99e-04116795MP:0001967
MousePhenoabnormal somatic sensory system morphology

SOX10 EPS8 FAT4 ERBB4 OTX2 LOXHD1 OTOF BBS2 POU1F1 PAX3 EYA1 SLC12A7

5.43e-047027912MP:0000959
MousePhenoabnormal trigeminal V mesencephalic nucleus morphology

OTX1 OTX2

6.50e-047792MP:0000906
MousePhenosmall endolymphatic duct

PAX3 EYA1

6.50e-047792MP:0008066
DomainOpsin_red/grn

OPN1MW3 OPN1LW OPN1MW

1.12e-073913IPR000378
DomainEYA_fam

EYA4 EYA1 EYA2

4.46e-074913IPR028472
DomainEYA_dom

EYA4 EYA1 EYA2

4.46e-074913IPR006545
DomainACTINS_1

ACTA1 ACTA2 ACTC1

6.16e-068913PS00406
DomainOPSIN

OPN1MW3 OPN1LW OPN1MW

1.31e-0510913PS00238
DomainOpsin

OPN1MW3 OPN1LW OPN1MW

1.79e-0511913IPR001760
DomainBAF250_C

ARID1B ARID1A

2.35e-052912IPR033388
DomainBAF250_C

ARID1B ARID1A

2.35e-052912PF12031
DomainOtx_TF

OTX1 OTX2

2.35e-052912IPR003025
DomainBAF250/Osa

ARID1B ARID1A

2.35e-052912IPR021906
DomainActin_CS

ACTA1 ACTA2 ACTC1

5.98e-0516913IPR004001
DomainOtx_TF_C

OTX1 OTX2

7.02e-053912IPR013851
DomainTF_Otx

OTX1 OTX2

7.02e-053912PF03529
DomainACTINS_2

ACTA1 ACTA2 ACTC1

7.24e-0517913PS00432
DomainActin/actin-like_CS

ACTA1 ACTA2 ACTC1

8.66e-0518913IPR020902
DomainACTINS_ACT_LIKE

ACTA1 ACTA2 ACTC1

1.02e-0419913PS01132
DomainKCL_cotranspt

SLC12A7 SLC12A5

1.40e-044912IPR000076
DomainHomeobox_CS

HOXB7 OTX1 OTX2 POU1F1 POU3F2 PAX3

2.98e-04186916IPR017970
DomainActin

ACTA1 ACTA2 ACTC1

4.56e-0431913IPR004000
DomainActin

ACTA1 ACTA2 ACTC1

4.56e-0431913PF00022
DomainACTIN

ACTA1 ACTA2 ACTC1

4.56e-0431913SM00268
DomainSLC12A_fam

SLC12A7 SLC12A5

4.85e-047912IPR004842
DomainSLC12_C

SLC12A7 SLC12A5

6.45e-048912IPR018491
DomainSLC12

SLC12A7 SLC12A5

6.45e-048912PF03522
DomainHomeobox

HOXB7 OTX1 OTX2 POU1F1 POU3F2 PAX3

9.96e-04234916PF00046
DomainHOMEOBOX_1

HOXB7 OTX1 OTX2 POU1F1 POU3F2 PAX3

1.04e-03236916PS00027
DomainHOX

HOXB7 OTX1 OTX2 POU1F1 POU3F2 PAX3

1.06e-03237916SM00389
DomainHOMEOBOX_2

HOXB7 OTX1 OTX2 POU1F1 POU3F2 PAX3

1.11e-03239916PS50071
DomainHomeobox_dom

HOXB7 OTX1 OTX2 POU1F1 POU3F2 PAX3

1.11e-03239916IPR001356
Domain-

ARID1B ARID1A

2.37e-03159121.10.150.60
DomainBRIGHT

ARID1B ARID1A

2.37e-0315912SM00501
DomainARID_dom

ARID1B ARID1A

2.37e-0315912IPR001606
DomainARID

ARID1B ARID1A

2.37e-0315912PS51011
DomainARID

ARID1B ARID1A

2.37e-0315912PF01388
Domain-

HOXB7 OTX1 OTX2 POU1F1 POU3F2 PAX3

2.61e-032839161.10.10.60
DomainPOU

POU1F1 POU3F2

2.70e-0316912SM00352
DomainPOU_2

POU1F1 POU3F2

2.70e-0316912PS00465
DomainPOU_dom

POU1F1 POU3F2

2.70e-0316912IPR000327
DomainPOU_3

POU1F1 POU3F2

2.70e-0316912PS51179
DomainPou

POU1F1 POU3F2

2.70e-0316912PF00157
DomainPOU_1

POU1F1 POU3F2

2.70e-0316912PS00035
DomainPOU

POU1F1 POU3F2

3.04e-0317912IPR013847
Domain-

EYA4 NT5DC2 EYA2

3.76e-03649133.40.50.1000
PathwayREACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION

OPN1MW2 OPN1MW3 OPN1LW

6.18e-068693MM14880
PathwayREACTOME_OPSINS

OPN1MW2 OPN1MW3 OPN1LW

1.31e-0510693MM15063
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

SOX10 ARID1B ATP6V0A1 POU3F2 PAX3 ARID1A

5.48e-05137696M48232
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

ACTA1 ACTA2 ACTC1 ITGB4

8.00e-0547694M39829
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

OPN1MW2 OPN1MW3 BCO2 LRP10 OPN1LW

8.58e-0592695MM14881
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

SOX10 ARID1B ATP6V0A1 POU3F2 ARID1A

9.99e-0595695M48268
Pubmed

Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

5.00e-11494429386880
Pubmed

Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.

SOX1 FOXO1 SOX10 ERBB4 OTX1 OTX2 POU3F2 EBF1 MEF2C

1.15e-1013494919030180
Pubmed

Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

2.50e-1059442937147
Pubmed

Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.

SOX1 ERBB4 OTX1 OTX2 POU3F2 PAX3 EBF1 MEF2C

2.61e-0913094819386638
Pubmed

Fibulin-1 is required for morphogenesis of neural crest-derived structures.

SOX10 ACTA1 ACTA2 PAX3

3.47e-09894418538758
Pubmed

Transcriptional profiling of murine retinas undergoing semi-synchronous cone photoreceptor differentiation.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

3.47e-09894431163126
Pubmed

Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

1.63e-081194424421398
Pubmed

Multiple hypothalamic cell populations encoding distinct visual information.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394321224225
Pubmed

Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394336216501
Pubmed

Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394334111401
Pubmed

Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394328751656
Pubmed

The molecular genetics and evolution of red and green color vision in vertebrates.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394311545071
Pubmed

Co-expression of murine opsins facilitates identifying the site of cone adaptation.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394312511072
Pubmed

Molecular determinants of human red/green color discrimination.

OPN1MW2 OPN1LW OPN1MW

1.91e-0839438185948
Pubmed

X-linked cone dystrophy caused by mutation of the red and green cone opsins.

OPN1MW2 OPN1LW OPN1MW

1.91e-08394320579627
Pubmed

Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394338410159
Pubmed

Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394323350963
Pubmed

Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394320471354
Pubmed

Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394310567724
Pubmed

Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394314500905
Pubmed

Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.

ACTA1 ACTA2 ACTC1

1.91e-0839437780165
Pubmed

Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394331469404
Pubmed

Mechanisms of spectral tuning in the mouse green cone pigment.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-0839439238068
Pubmed

Emergence of novel color vision in mice engineered to express a human cone photopigment.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-08394317379811
Pubmed

The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.

OPN1MW2 OPN1MW3 OPN1LW

1.91e-0839437958444
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

SOX10 FLI1 HOXB7 OTX1 OTX2 NFKB2 POU1F1 POU3F2 DMRTA1 PAX3 RFX4 MEF2C

2.84e-08544941228473536
Pubmed

Essential functions of synapsins I and II in synaptic vesicle regulation.

OPN1MW2 OPN1MW3 OPN1LW ITGA6

3.51e-08139447777057
Pubmed

Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

4.91e-081494423171847
Pubmed

Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.

ACTC1 ITGA6 PAX3 ITGB4

6.68e-081594415366018
Pubmed

Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

6.68e-081594430783126
Pubmed

Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494328103478
Pubmed

Molecular biology of the visual pigments.

OPN1MW2 OPN1LW OPN1MW

7.63e-0849433303660
Pubmed

Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494326438865
Pubmed

Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494317249565
Pubmed

Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494338060327
Pubmed

Contribution of M-opsin-based color vision to refractive development in mice.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494334126082
Pubmed

Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494331461375
Pubmed

Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-0849438088841
Pubmed

Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494331846668
Pubmed

Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494316567464
Pubmed

S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494324801621
Pubmed

Melanopsin Contributions to the Representation of Images in the Early Visual System.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494328528909
Pubmed

Melanopsin-driven light adaptation in mouse vision.

OPN1MW2 OPN1MW3 OPN1LW

7.63e-08494325308073
Pubmed

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent MĂĽller glia.

OPN1MW2 OPN1MW3 OTX1 OTX2 OPN1LW

7.91e-084094534677125
Pubmed

Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad.

SOX10 ACTA1 ACTA2 PAX3

8.88e-081694418397758
Pubmed

The role of the Rx homeobox gene in retinal progenitor proliferation and cell fate specification.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

1.16e-071794429665410
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ARID1B EYA4 PDHB SUPT5H ACTA1 LPP FBXL12 ITGA6 EYA1 STAM EYA2 PHF8 ARID1A AP3B1 SLC12A7

1.42e-071049941527880917
Pubmed

Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4.

OTX1 EBF1 EYA1 EYA2

1.49e-071894419027001
Pubmed

ATX expression and LPA signalling are vital for the development of the nervous system.

SOX1 SOX10 ACTA2 PAX3

1.49e-071894420079728
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX1 FOXO1 SOX10 FLI1 OTX1 OTX2 NFKB2 POU1F1 POU3F2 DMRTA1 PAX3 EBF1 RFX4 MEF2C

1.56e-07908941419274049
Pubmed

Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

1.88e-071994420110327
Pubmed

Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.

ERBB4 ACTA1 ACTA2 ACTC1

1.88e-071994430700554
Pubmed

Temporal profiling of photoreceptor lineage gene expression during murine retinal development.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

1.88e-071994428288836
Pubmed

The Role of Sorting Nexin 17 in Cardiac Development.

SOX10 FAT4 ERBB4 MEF2C

1.88e-071994434988124
Pubmed

Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594326818794
Pubmed

A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594322090509
Pubmed

Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594327033727
Pubmed

The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594311055434
Pubmed

Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594336631163
Pubmed

A common integration locus in type B retrovirus-induced thymic lymphomas.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-0759431333116
Pubmed

Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594310723722
Pubmed

Melanopsin-based brightness discrimination in mice and humans.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594322633808
Pubmed

Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594324058409
Pubmed

Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.

OPN1MW2 OPN1MW3 OPN1LW

1.90e-07594334099749
Pubmed

Typing recombinant inbred mouse strains for microsatellite markers on chromosomes 10, 16, 18, 19, and X.

OPN1MW2 OPN1MW3 OPN1LW POU1F1

2.35e-07209448589516
Pubmed

Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.

ACTA1 ACTA2 ACTC1 MEF2C

2.89e-072194420230754
Pubmed

Myocardial Mycn is essential for mouse ventricular wall morphogenesis.

ERBB4 ACTA1 ACTA2 ACTC1

2.89e-072194423063798
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

EYA4 KIDINS220 PDHB SUPT5H NT5DC2 ACAD9 PSMA3 LPP FBXL12 ANKRD17 EYA1 EYA2 AP3B1 HNRNPLL

3.63e-07974941428675297
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTA1 ACTA2 ACTC1

3.80e-0769439971772
Pubmed

Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors.

SOX10 POU3F2 PAX3

3.80e-07694311029584
Pubmed

Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.

OPN1MW2 OPN1MW3 OPN1LW

3.80e-0769438872469
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTA1 ACTA2 ACTC1

3.80e-07694310074138
Pubmed

A thyroid hormone receptor that is required for the development of green cone photoreceptors.

OPN1MW2 OPN1MW3 OPN1LW

3.80e-07694311138006
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTA1 ACTA2 ACTC1

3.80e-07694322989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTA1 ACTA2 ACTC1

3.80e-0769431540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTA1 ACTA2 ACTC1

3.80e-07694311709093
Pubmed

Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.

OPN1MW2 OPN1MW3 OPN1LW

3.80e-07694323288843
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTA1 ACTA2 ACTC1

3.80e-07694310049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTA1 ACTA2 ACTC1

3.80e-07694312009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTA1 ACTA2 ACTC1

3.80e-07694323811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTA1 ACTA2 ACTC1

3.80e-07694319883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTA1 ACTA2 ACTC1

3.80e-07694321917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTA1 ACTA2 ACTC1

3.80e-0769438661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTA1 ACTA2 ACTC1

3.80e-07694323017337
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTA1 ACTA2 ACTC1

3.80e-07694323875777
Pubmed

Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase.

OPN1MW2 OPN1MW3 OPN1LW

3.80e-07694310395695
Pubmed

EYA4, a novel vertebrate gene related to Drosophila eyes absent.

EYA4 EYA1 EYA2

3.80e-0769439887327
Pubmed

Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis.

OPN1MW2 OPN1MW3 OPN1LW

3.80e-07694317436273
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTA1 ACTA2 ACTC1

3.80e-0769439841925
Pubmed

Telomere-related markers for the pseudoautosomal region of the mouse genome.

OPN1MW2 OPN1MW3 OPN1LW

3.80e-0769431549575
Pubmed

Notch 1 inhibits photoreceptor production in the developing mammalian retina.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

6.06e-072594416452096
Pubmed

Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity.

OPN1MW2 OPN1MW3 OTX2 OPN1LW

6.06e-072594433795534
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTA1 ACTA2 ACTC1

6.64e-07794322535526
Pubmed

NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina.

OPN1MW2 OPN1MW3 OPN1LW

6.64e-07794318199774
Pubmed

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

OPN1MW2 OPN1MW3 OPN1LW

6.64e-0779438378320
Pubmed

Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina.

OPN1MW2 OPN1MW3 OPN1LW

6.64e-07794330799247
Pubmed

Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.

OPN1MW2 OPN1MW3 OPN1LW

6.64e-07794316574740
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTA1 ACTA2 ACTC1

6.64e-07794318443296
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTA1 ACTA2 ACTC1

6.64e-07794322640593
Pubmed

Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.

OPN1MW2 OPN1MW3 OPN1LW

6.64e-07794319332056
InteractionLASP1 interactions

FOXO1 LENG8 OTX1 PSMA3 ACTA1 LPP ACTA2 ACTC1 POU1F1

1.76e-06247919int:LASP1
InteractionSIX2 interactions

EYA4 ANKRD17 EYA1 EYA2

8.47e-0629914int:SIX2
InteractionBICRA interactions

ARID1B EYA4 SUPT5H ACTC1 ARID1A

1.30e-0567915int:BICRA
InteractionARID1B interactions

SOX10 FLI1 ARID1B SUPT5H ACTC1 EYA2 ARID1A

1.56e-05177917int:ARID1B
GeneFamilyOpsin receptors

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

6.66e-0811704215
GeneFamilyEYA transcriptional coactivator and phosphatases

EYA4 EYA1 EYA2

2.22e-0747031044
GeneFamilyActins

ACTA1 ACTA2 ACTC1

1.10e-066703929
GeneFamilyAT-rich interaction domain containing

ARID1B ARID1A

1.50e-0315702418
GeneFamilySRY-boxes

SOX1 SOX10

2.42e-0319702757
GeneFamilyPOU class homeoboxes and pseudogenes

POU1F1 POU3F2

3.55e-0323702523
GeneFamilyPRD class homeoboxes and pseudogenes

OTX1 OTX2 PAX3

5.46e-0392703521
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

SOX1 FLI1 FAT4 OTX1 EYA4 COL12A1 OTX2 POU3F2 PAX3 LTBR EBF1 EYA1 SLC12A7 MGARP SLC29A4 SLC2A4

7.00e-0710749016M1941
CoexpressionBENPORATH_EED_TARGETS

SOX1 FLI1 EPS8 HOXB7 ERBB4 OTX1 EYA4 COL12A1 OTX2 POU3F2 PAX3 EBF1 EYA2 ARID1A MGARP

3.03e-0610599015M7617
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

EPS8 ARID1B LPP ACTA2 EBF1 MEF2C

1.60e-05155906M39246
CoexpressionMISIAK_ANAPLASTIC_THYROID_CARCINOMA_UP

OTX1 ACTC1 POU3F2 PAX3

1.74e-0545904M45041
CoexpressionAPRELIKOVA_BRCA1_TARGETS

ACTA1 ACTA2 ACTC1 STAM

2.25e-0548904M1568
CoexpressionAPRELIKOVA_BRCA1_TARGETS

ACTA1 ACTA2 ACTC1 STAM

2.45e-0549904MM1178
CoexpressionGSE40274_IRF4_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

SUPT5H ACAD9 NFKB2 GART ZBTB8A PHF8

3.96e-05182906M9154
CoexpressionDARWICHE_SQUAMOUS_CELL_CARCINOMA_DN

VPS37A ACAD9 ACTA1 ACTA2 MEF2C YTHDF2

4.47e-05186906M1140
CoexpressionBENPORATH_SUZ12_TARGETS

SOX1 SOX10 FLI1 EPS8 HOXB7 ERBB4 OTX1 OTX2 ABHD6 PAX3 EYA2 MGARP SLC12A5

5.16e-0510359013M9898
CoexpressionGSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN

OTX1 TESMIN PSMA3 FBXL12 PAX3 STAM

5.99e-05196906M8024
CoexpressionDARWICHE_SQUAMOUS_CELL_CARCINOMA_DN

VPS37A ACAD9 ACTA1 ACTA2 MEF2C YTHDF2

6.88e-05201906MM502
CoexpressionBENPORATH_ES_WITH_H3K27ME3

FLI1 HOXB7 ERBB4 OTX1 EYA4 COL12A1 OTX2 PARP8 POU3F2 PAX3 EBF1 MGARP RFX4

1.09e-0411159013M10371
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500

OTX1 OTX2 ZSWIM5 RAVER2 ACTA1 DMRTA1 PABPC1L PAX3 EYA1 EYA2 RFX4 SLC2A4

7.53e-074918712Facebase_RNAseq_e9.5_Olfactory Placode_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#3

OTX1 EYA4 RAVER2 DMRTA1 PABPC1L PAX3 EYA1 EYA2

2.12e-05283878Facebase_RNAseq_e9.5_Olfactory Placode_1000_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_top-relative-expression-ranked_100

CLCA2 ACTA1 LPP ACTA2 ACTC1

2.32e-0583875gudmap_developingLowerUrinaryTract_P1_bladder_100_B
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#2_top-relative-expression-ranked_500

EPS8 LPP ACTA2 MEF2C

2.61e-0542874gudmap_kidney_adult_Mesangium_Meis_k2_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

FLI1 EPS8 EYA4 KLHL28 CLCA2 ACTA1 TENM1 ACTC1 DMRTA1 PAX3 EBF1 EYA1 ABCG5

3.44e-058368713gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500

FLI1 HOXB7 ERBB4 EYA4 COL12A1 ACTA2 POU3F2 PAX3 EBF1 RFX4

3.66e-054988710PCBC_ratio_EB_vs_SC_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_500

CLCA2 ACTA1 ACTA2 ACTC1

4.46e-0548874gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k4
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_100

OTX1 OTX2 POU3F2 DMRTA1 PAX3

5.43e-0599875PCBC_ECTO_100
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_100

OTX1 OTX2 POU3F2 DMRTA1 PAX3

5.43e-0599875PCBC_ECTO_fibroblast_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_100

OTX1 OTX2 ZSWIM5 DMRTA1 RFX4

5.70e-05100875Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_100
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500

FAT4 COL12A1 CLCA2 ACTA2 DCBLD1 ACTC1 ITGA6 DMRTA1

1.09e-04357878gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_500_k-means-cluster#2

RAVER2 DMRTA1 PABPC1L PAX3 EYA1 EYA2

1.24e-04188876Facebase_RNAseq_e9.5_Olfactory Placode_500_K2
CoexpressionAtlasB cells, B.FrE.BM, CD19+ IgM+ AA4.1+ HSA+, Bone marrow, avg-3

FOXO1 EPS8 ATP6V0A1 NFKB2 EBF1 EYA1 TLR9 MEF2C

1.55e-04376878GSM399438_500
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

OTX1 EYA4 OTX2 ZSWIM5 RAVER2 ACTA1 DMRTA1 PABPC1L PAX3 EYA1 EYA2 RFX4 SLC2A4

1.59e-049738713Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_100

ACTA1 ACTA2 ACTC1

1.61e-0426873gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

TBC1D16 FLI1 EPS8 EYA4 TENM1 ACTC1 DMRTA1 PAX3 EYA1 STAM AP3B1 ABCG5

1.76e-048508712gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500

OTX1 EYA4 OTX2 ZSWIM5 RAVER2 ACTA1 DMRTA1 EYA1 EYA2

1.94e-04495879Facebase_RNAseq_e10.5_Olfactory Pit_500
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_100

COL12A1 ACTA2 EBF1

2.02e-0428873gudmap_kidney_P0_JuxtaGlom_Ren1_k3_100
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100

ACTA1 ACTA2 ACTC1

2.02e-0428873gudmap_developingLowerUrinaryTract_P1_bladder_B_100_k3
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#5

OTX1 EYA4 RAVER2 DMRTA1 PABPC1L PAX3 EYA1 EYA2

2.02e-04391878Facebase_RNAseq_e9.5_Olfactory Placode_2500_K5
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_100

FAT4 ACTC1 EBF1 EYA2

2.31e-0473874gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_200

EYA4 COL12A1 ACTA2 ACTC1 EYA1

3.48e-04147875gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500

FAT4 EYA4 KLHL28 CLCA2 ZSWIM5 TENM1 EBF1 EYA1

3.66e-04427878DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500

FLI1 EPS8 EYA4 KLHL28 TENM1 ACTC1 DMRTA1 EYA1

3.77e-04429878gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_500

FAT4 EYA4 TENM1 EYA1

4.32e-0486874DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_100

CLCA2 ACTA1 ACTA2 ACTC1

4.32e-0486874gudmap_developingLowerUrinaryTract_P1_bladder_100_J
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_100

COL12A1 ACTA2 ACTC1 EBF1

4.52e-0487874gudmap_kidney_P0_JuxtaGlom_Ren1_100
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_top-relative-expression-ranked_200

CLCA2 ACTA1 LPP ACTA2 ACTC1

5.13e-04160875gudmap_developingLowerUrinaryTract_P1_bladder_200_B
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000

FLI1 EPS8 FAT4 ZNF469 KLHL28 CLCA2 ACTA2 TENM1 ACTC1 MEF2C SLC12A5

5.46e-048268711DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_1000

CLCA2 ACTA1 ACTA2 ACTC1

5.58e-0492874gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#3_top-relative-expression-ranked_100

ACTA1 ACTC1

5.86e-049872gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_100_k3
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_500

FAT4 COL12A1 DCBLD1 ITGA6

6.05e-0494874gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_500
CoexpressionAtlasB cells, B.T1.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23-, Spleen, avg-3

FOXO1 EPS8 ATP6V0A1 NFKB2 EBF1 TLR9 MEF2C

6.18e-04353877GSM538213_500
CoexpressionAtlasratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

SOX1 SOX10 ERBB4 OTX1 ACTA2 ABHD6 POU3F2 DMRTA1 PAX3 RFX4 KIF25

6.79e-048488711ratio_ECTO_vs_SC_2500_K3
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#2_top-relative-expression-ranked_200

EYA4 ACTC1 EYA1

6.79e-0442873gudmap_kidney_e15.5_Podocyte_MafB_k2_200
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_100

OTX1 OTX2 ACTA1 DMRTA1

7.08e-0498874Facebase_RNAseq_e9.5_Olfactory Placode_100
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000

FLI1 FAT4 HOXB7 ERBB4 EYA4 COL12A1 BCO2 ACTA2 POU3F2 PAX3 EBF1 RFX4

7.21e-049948712PCBC_ratio_EB_vs_SC_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_100

OTX1 OTX2 DMRTA1 EYA2

7.64e-04100874Facebase_RNAseq_e10.5_Olfactory Pit_100
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 OTX1 DMRTA1 ETNPPL EYA2 RFX4 ITGB4

1.29e-0718693741e03be964044dae690d566bd078dab3d8045eba
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

FLI1 EPS8 ACTA2 DCBLD1 ITGA6 EBF1 MEF2C

1.49e-07190937a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPS8 LPP ACTA2 ACTC1 EBF1 MEF2C SLC2A4

1.85e-071969371d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPS8 LPP ACTA2 ACTC1 EBF1 MEF2C SLC2A4

1.85e-07196937aacec48285bcb7ccf1b538187071885e3602cc49
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 LPP ACTA2 EBF1 MEF2C SLC2A4

1.71e-06173936fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 LPP ACTA2 EBF1 MEF2C SLC2A4

1.71e-06173936901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

EPS8 LPP ACTA2 DCBLD1 EBF1 MEF2C

2.37e-06183936e3835db4795362b0442d5893baf2a78efcc20428
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 EPS8 FAT4 ERBB4 COL12A1 SLC29A4

2.37e-061839365e361be3ae3fe05098968e58427630127bd12675
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

EPS8 LPP ACTA2 DCBLD1 EBF1 MEF2C

2.52e-06185936acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

COL12A1 LPP ACTA2 TENM1 ACTC1 SLC2A4

2.77e-0618893674f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

EPS8 ERBB4 CLCA2 EYA1 EYA2 ITGB4

2.86e-0618993684d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADCY10 EPS8 COL12A1 ACTA2 EBF1 SLC2A4

3.13e-06192936fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NT5DC2 ACTA2 ACTC1 EBF1 MEF2C SLC2A4

3.32e-061949365099e6ad7c19e5f8b73449d904aaefd97f1b1959
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NT5DC2 ACTA2 ACTC1 EBF1 MEF2C SLC2A4

3.32e-0619493671734ef7b34ab33b349595368176fa0e1175d4d0
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

EPS8 ACTA1 LPP ACTA2 ACTC1 MEF2C

3.52e-06196936541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 ACTA1 LPP ACTA2 ACTC1 EBF1

3.52e-06196936ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|367C / Donor, Lineage, Cell class and subclass (all cells)

EPS8 LPP ACTA2 ACTC1 EBF1 SLC2A4

3.52e-06196936c390ef0adff35111989a30dff86b7c5db1a89873
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|367C / Donor, Lineage, Cell class and subclass (all cells)

EPS8 LPP ACTA2 ACTC1 EBF1 SLC2A4

3.52e-061969362f76f050083483f0880639e6c34ff349caac3503
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 ACTA1 LPP ACTA2 ACTC1 EBF1

3.52e-0619693670b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 COL12A1 NT5DC2 ACTA2 EBF1 MEF2C

3.63e-06197936bc6c530330907a5ec823cc243c8e9c9e340cfb9c
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EYA4 COL12A1 CLCA2 NT5DC2 ITGA6 SLC44A4

3.63e-06197936d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EYA4 COL12A1 CLCA2 NT5DC2 ITGA6 SLC44A4

3.63e-0619793680b05c8ad9c1edc5dea3236079372475431343fe
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 COL12A1 NT5DC2 ACTA2 EBF1 MEF2C

3.63e-0619793677fe092aae8f05fe137680506892d2f61071d6ea
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|343B / Donor, Lineage, Cell class and subclass (all cells)

COL12A1 ACTA1 LPP ACTA2 ACTC1 EBF1

3.63e-0619793678d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL12A1 ACTA1 LPP ACTA2 ACTC1 EBF1

3.63e-0619793631bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPS8 ACTA1 LPP ACTA2 ACTC1 MEF2C

3.96e-062009362bc7f462a551292de2501028164573935232f899
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FOXO1 FLI1 EPS8 ITGA6 ITGB4 MEF2C

3.96e-062009367eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPS8 ACTA2 ACTC1 EBF1 MEF2C SLC2A4

3.96e-06200936b22cae282591d8dead9869c2adbb9632615f50f7
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPS8 ACTA1 LPP ACTA2 ACTC1 MEF2C

3.96e-062009368b80a65b69b36ed405214564b939452c90aa40d6
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

PARP8 PABPC1L SLC44A4 SLC29A4 SLC12A5

1.13e-05140935407691970ec72a3afb45e431cf48814546b8acff
ToppCellTCGA-Uvea|World / Sample_Type by Project: Shred V9

SOX1 TBC1D16 ZNF469 PAX3 KIF25

1.17e-05141935015451a83087f2705d3315ebc8f23797c6f10ed6
ToppCellCerebellum-Macroglia-ASTROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

SOX1 POU3F2 ETNPPL PAX3 RFX4

1.63e-0515193571841d2001200d1595c85c2b007ee20791a72927
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1|Cerebellum / BrainAtlas - Mouse McCarroll V32

SOX1 POU3F2 ETNPPL PAX3 RFX4

1.63e-0515193560aced0c1cc6b509b73308d03d58a3c44d712ef4
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

OTX1 PRSS16 XYLB EYA1 ITGB4

2.03e-0515893598712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MMEL1 CLCA2 EYA1 EYA2 ITGB4

2.29e-05162935112fa4de685727f6c8bf6fc4afb82de0524070ad
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERBB4 OTOF ACTA1 ACTA2 ACTC1

2.57e-05166935390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ERBB4 OTOF ACTA1 ACTA2 ACTC1

2.57e-051669359a341dc7b756252caeaac1e934384911c880a634
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OTOF LPP ACTA2 ACTC1 SLC2A4

2.88e-05170935cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OTOF LPP ACTA2 ACTC1 SLC2A4

2.88e-05170935da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 ERBB4 COL12A1 LOXHD1 SLC29A4

2.97e-05171935a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMEL1 OTOF ACTA2 ACTC1 SLC2A4

2.97e-0517193582de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMEL1 OTOF ACTA2 ACTC1 SLC2A4

2.97e-0517193509e653973962fb884878089d281f0947f7a285f6
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPS8 ACTA2 EBF1 C2orf78 MEF2C

3.05e-05172935107417cfab7775bc1f80807115047abfb50b7a7e
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXO1 FAT4 COL12A1 LPP ACTA2

3.31e-051759351799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 EPS8 LOXHD1 BCO2 ITGA6

3.40e-0517693525ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYA4 BCO2 ACTA1 ACTC1 COLQ

3.40e-051769359df7a124ebafb0087da0cda133a394275d7bed81
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 FAT4 ERBB4 DMRTA1 SLC12A7

3.50e-0517793584116796ca4c7007508c0f1a68a1135c7b922278
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 LPP ACTA2 EBF1 MEF2C

3.50e-05177935a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 OTX1 CLCA2 EYA1 EYA2

3.50e-05177935a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 LPP ACTA2 EBF1 MEF2C

3.50e-051779353645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ERBB4 OTX1 CLCA2 EYA1 EYA2

3.50e-05177935363e07b0f347f3716d530a28ead854b98e27d37c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 LTBR EBF1 SLC12A7 SLC2A4

3.69e-05179935368f7e91e9c2c854c8778788cead022d158d1122
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OTOGL NT5DC2 ACTA2 NPAP1 EBF1

3.69e-05179935dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 FAT4 ERBB4 COL12A1 LOXHD1

3.69e-0517993501302505816f272243659e20d751b61a198a2fc0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 LTBR EBF1 SLC12A7 SLC2A4

3.69e-0517993511e434fc49bc0a806197f21debcac8337e0502aa
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 ERBB4 COL12A1 LOXHD1 SLC29A4

3.79e-05180935c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

EYA4 CLCA2 EYA1 EYA2 ITGB4

3.89e-051819356d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ARID1B DDX17 PARP8 LPP HNRNPLL

3.89e-05181935f2315414e714ac86211546a935660c4be6e85f1b
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA6 ETNPPL EYA2 RFX4 ITGB4

3.89e-051819350c3f469bed108994ed696230e3c30343f7a301d3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX1 POU3F2 ETNPPL PAX3 RFX4

3.99e-05182935904804813849b7f7f716ba1554d33b07bc0a701e
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

EYA4 BCO2 ACTA1 ACTC1 COLQ

3.99e-05182935287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX10 ERBB4 ITGA6 PAX3 EYA1

3.99e-05182935f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX1 POU3F2 ETNPPL PAX3 RFX4

3.99e-051829355d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 ZNF469 ITGA6 EBF1 MEF2C

4.10e-05183935dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 LTBR EBF1 SLC12A7 SLC2A4

4.10e-05183935944f7458b9127356815f75c88bbf7015ebdc8ec1
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

OTX1 CLCA2 EYA1 EYA2 SLC44A4

4.10e-05183935940cbe298e9c53b5622af09264586ed823d3141f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 ZNF469 ITGA6 EBF1 MEF2C

4.10e-051839354759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 EPS8 FAT4 ERBB4 SLC29A4

4.10e-051839356e6128c5be5e0a2db6d84eecbf4dddd02d0216f8
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

ZNF469 NT5DC2 GART DCBLD1 MEF2C

4.10e-05183935d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes-Pericyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPS8 LTBR EBF1 SLC12A7 SLC2A4

4.10e-05183935cee6b821adff538078232689965d3e6c131e7d14
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL12A1 LOXHD1 OTOGL TENM1

4.21e-051849352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LPP ACTA2 TENM1 ACTC1 SLC2A4

4.21e-0518493539168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL12A1 LOXHD1 OTOGL TENM1

4.21e-05184935ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 EPS8 FAT4 ERBB4 SLC12A7

4.21e-0518493532473dbdb2de66391157c5814ef34e790806e4f2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 COL12A1 LOXHD1 OTOGL TENM1

4.21e-051849352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 COL12A1 ACTA2 EBF1 MEF2C

4.32e-051859357092436b4db90289516ed130ade596e3021cffaf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 COL12A1 ACTA2 EBF1 MEF2C

4.32e-0518593551dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 COL12A1 ACTA2 EBF1 MEF2C

4.32e-05185935a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

EPS8 LPP DCBLD1 EBF1 MEF2C

4.32e-05185935ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 COL12A1 ACTA2 EBF1 MEF2C

4.32e-05185935a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ETNPPL EYA1 EYA2 RFX4 ITGB4

4.43e-0518693573cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOGL ACAD9 ACTA2 ACTC1 SLC2A4

4.43e-05186935aa88d9573a237b2b8e6025fee31f69fbce824497
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOGL ACAD9 ACTA2 ACTC1 SLC2A4

4.43e-05186935ecc5acd111a6ee50d59544d1bdd7ed94e2812aae
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACTA2 ACTC1 EBF1 MEF2C SLC2A4

4.43e-051869354780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 ETNPPL EYA2 RFX4 ITGB4

4.54e-05187935dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 ETNPPL EYA2 RFX4 ITGB4

4.54e-05187935ae90c263f80c36a410150d499e268d198944a3d9
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

EPS8 EYA4 COL12A1 ACTA2 EBF1

4.54e-0518793576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 ETNPPL EYA2 RFX4 ITGB4

4.54e-051879355d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 ETNPPL EYA2 RFX4 ITGB4

4.54e-051879355c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 EPS8 FAT4 ERBB4 COL12A1

4.54e-0518793502105c82a9ba79d2f19e002188377fc3440770c2
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

FOXO1 EPS8 EYA4 BCO2 ITGA6

4.54e-05187935ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

ERBB4 CLCA2 EYA1 EYA2 ITGB4

4.54e-051879358407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

LPP ACTA2 ACTC1 MEF2C SLC2A4

4.66e-051889359ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EYA4 COL12A1 ACTA2 ACTC1 EYA2

4.66e-05188935f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACTA2 ACTC1 EBF1 MEF2C SLC2A4

4.78e-05189935975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

EPS8 ITGA6 EBF1 BEND2 MEF2C

4.78e-05189935f4865b7db16de15120504147a8016ac522ad242a
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 FOXO1 EPS8 ERBB4 EYA4

4.90e-051909352f54da2bee411f8868348a4c37034184b8f58a89
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 ETNPPL EYA2 RFX4 ITGB4

4.90e-051909355c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 ETNPPL EYA2 RFX4 ITGB4

4.90e-051909353a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 LPP ACTA2 EBF1 MEF2C

4.90e-051909355681c211baeed4af82a2bbc13420f6a7b487581c
Diseaseblue cone monochromacy (implicated_via_orthology)

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

9.25e-114934DOID:0050679 (implicated_via_orthology)
DiseaseHereditary hearing loss and deafness

SOX10 EYA4 LOXHD1 OTOF PDHB PAX3 EYA1

4.17e-07146937cv:C0236038
Diseaseeye disease (implicated_via_orthology)

EYA4 EYA1 EYA2

6.02e-076933DOID:5614 (implicated_via_orthology)
Diseasebranchiootorenal syndrome (implicated_via_orthology)

EYA4 EYA1 EYA2

1.05e-067933DOID:14702 (implicated_via_orthology)
DiseaseMoyamoya disease (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

1.68e-068933DOID:13099 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

1.68e-068933DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

1.68e-068933DOID:0081112 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

1.68e-068933DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

3.58e-0610933DOID:10486 (implicated_via_orthology)
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

3.58e-0610933DOID:13832 (implicated_via_orthology)
Diseaseposterior thigh muscle fat infiltration measurement

EYA4 EBF1 EYA1 EYA2

4.49e-0635934EFO_0020934
DiseaseCone monochromatism

OPN1LW OPN1MW

9.83e-062932cv:C0339537
DiseaseBORNHOLM EYE DISEASE

OPN1LW OPN1MW

9.83e-062932C3159311
DiseaseAchromatopsia incomplete, X-linked

OPN1LW OPN1MW

9.83e-062932C2931753
DiseaseRed-green dyschromatopsia

OPN1LW OPN1MW

9.83e-062932cv:C0155016
DiseaseCone monochromatism

OPN1LW OPN1MW

9.83e-062932C0339537
DiseaseBLUE CONE MONOCHROMACY

OPN1LW OPN1MW

9.83e-062932303700
Diseaseblue cone monochromacy (is_implicated_in)

OPN1LW OPN1MW

9.83e-062932DOID:0050679 (is_implicated_in)
Diseasejunctional epidermolysis bullosa with pyloric atresia (is_implicated_in)

ITGA6 ITGB4

9.83e-062932DOID:0060733 (is_implicated_in)
Diseasetriglyceride measurement, alcohol drinking

GALNT2 EBF1 EYA2 SLC44A4 ARID1A

1.58e-0599935EFO_0004329, EFO_0004530
Diseasetriglyceride measurement, alcohol consumption measurement

GALNT2 EBF1 EYA2 SLC44A4 ARID1A

1.74e-05101935EFO_0004530, EFO_0007878
DiseaseRHABDOMYOSARCOMA 2

FOXO1 PAX3

2.94e-053932268220
Diseasealveolar rhabdomyosarcoma (is_implicated_in)

FOXO1 PAX3

2.94e-053932DOID:4051 (is_implicated_in)
DiseaseEpidermolysis bullosa with pyloric atresia

ITGA6 ITGB4

2.94e-053932C1856934
DiseaseAlveolar rhabdomyosarcoma

FOXO1 PAX3

2.94e-053932cv:C0206655
Diseaseinsulin resistance

DMRTA1 EYA1 AP3B1 SLC2A4

3.69e-0559934EFO_0002614
DiseaseColorectal Carcinoma

EYA4 PARP8 NPAP1 TENM1 DMRTA1 TLR9 STAM SLC44A4 ARID1A SLC12A5

7.46e-057029310C0009402
DiseaseCombined pituitary hormone deficiencies, genetic form

OTX2 POU1F1

9.77e-055932cv:C4273747
DiseaseAlveolar rhabdomyosarcoma

FOXO1 PAX3

9.77e-055932C0206655
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1B ARID1A

9.77e-055932C3281201
DiseaseNonsyndromic Deafness

EYA4 LOXHD1 OTOGL SLC44A4

1.28e-0481934C3711374
DiseasePituitary Hormone Deficiency, Combined, 1

OTX2 POU1F1

1.46e-046932C2751608
DiseaseWaardenburg Syndrome

SOX10 PAX3

1.46e-046932C3266898
Diseasesmoking behavior, BMI-adjusted waist-hip ratio

EYA4 NT5DC2 EYA1 EYA2

1.61e-0486934EFO_0004318, EFO_0007788
Diseasejunctional epidermolysis bullosa (is_implicated_in)

ITGA6 ITGB4

2.04e-047932DOID:3209 (is_implicated_in)
Diseasepanhypopituitarism (is_implicated_in)

OTX2 POU1F1

2.04e-047932DOID:9410 (is_implicated_in)
Diseasehearing impairment

EYA4 LOXHD1 OTOF EYA1

2.66e-0498934C1384666
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB4 ARID1B ARID1A

2.96e-0441933C0496956
DiseaseBreast adenocarcinoma

ERBB4 ARID1B ARID1A

2.96e-0441933C0858252
Diseasealcohol use disorder (implicated_via_orthology)

EPS8 ERBB4 ARID1B DDX17 ARID1A

3.89e-04195935DOID:1574 (implicated_via_orthology)
Diseaseneuroblastoma (is_implicated_in)

ARID1B ARID1A

4.35e-0410932DOID:769 (is_implicated_in)
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

DCBLD1 RFX4 HNRNPLL

4.73e-0448933EFO_0009268, MONDO_0001627, MONDO_0004975
DiseaseCoffin-Siris syndrome

ARID1B ARID1A

7.49e-0413932C0265338
Diseasecortical thickness

ZNF469 ARID1B EYA4 COL12A1 PDHB NT5DC2 DMRTA1 EBF1 EYA1 RFX4 MEF2C

7.56e-0411139311EFO_0004840
Diseaseimmunoglobulin lambda-like polypeptide 1 measurement

EBF1 MEF2C

1.15e-0316932EFO_0801688
Diseasekeratoconus

FOXO1 ZNF469 COL12A1

1.20e-0366933MONDO_0015486
Diseaselymphocyte percentage of leukocytes

FLI1 ACTA2 DMRTA1 LTBR EBF1 ARID1A DTHD1 MEF2C

1.21e-03665938EFO_0007993
Diseaseallergic disease

FOXO1 ARID1B LPP STAM EYA2

1.37e-03258935MONDO_0005271
Diseaseautoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease

MMEL1 LPP

1.45e-0318932EFO_0003779, EFO_0004237, EFO_0006812
Diseasealbumin:globulin ratio measurement

TBC1D16 FLI1 GALNT2

1.61e-0373933EFO_0005128
Diseasegranulocyte percentage of myeloid white cells

FOXO1 LPP DMRTA1 LTBR ARID1A

1.61e-03268935EFO_0007997
Diseasediet measurement

LENG8 ZNF469 ERBB4 ARID1B OTX1 PRSS16 PARP8 DMRTA1 EBF1 MEF2C

1.73e-0310499310EFO_0008111
DiseaseDeaf Mutism

OTOF PAX3

1.80e-0320932C4082305
DiseaseDeafness, Acquired

OTOF PAX3

1.80e-0320932C0751068
DiseaseHearing Loss, Extreme

OTOF PAX3

1.80e-0320932C0086395
DiseaseComplete Hearing Loss

OTOF PAX3

1.80e-0320932C0581883
Diseasecorneal hysteresis

FOXO1 ZNF469

1.80e-0320932EFO_0010066
DiseaseBilateral Deafness

OTOF PAX3

1.80e-0320932C3665473
DiseasePrelingual Deafness

OTOF PAX3

1.80e-0320932C0011052
Diseaseneoplasm of mature B-cells

FLI1 LPP

1.80e-0320932EFO_0000096
DiseaseNonsyndromic genetic hearing loss

EYA4 LOXHD1 OTOF

1.80e-0376933cv:C5680182
Diseaseanthropometric measurement

ZNF469 EBF1 EYA1 AP3B1

2.00e-03168934EFO_0004302
Diseaseblood pressure

VPS37A MEF2C

2.18e-0322932EFO_0004325
DiseaseGranulomatous Slack Skin

NFKB2 ARID1A

2.18e-0322932C0376407
Diseasemonocyte percentage of leukocytes

FOXO1 FLI1 LPP DMRTA1 LTBR EBF1 ARID1A MEF2C

2.19e-03731938EFO_0007989
Diseaseaspartate aminotransferase measurement

EYA4 GALNT2 PDHB DMRTA1 LTBR EYA1 STAM EYA2 SLC2A4

2.21e-03904939EFO_0004736
DiseaseEpilepsy, Cryptogenic

ARID1B MEF2C SLC12A5

2.24e-0382933C0086237
DiseaseAwakening Epilepsy

ARID1B MEF2C SLC12A5

2.24e-0382933C0751111
DiseaseAura

ARID1B MEF2C SLC12A5

2.24e-0382933C0236018
DiseaseRheumatoid Arthritis

MMEL1 GART ITGA6 MGARP

2.27e-03174934C0003873
DiseaseCCL11 measurement

LPP EBF1

2.38e-0323932EFO_0005188
DiseaseLymphoma, T-Cell, Cutaneous

NFKB2 ARID1A

2.38e-0323932C0079773
Diseasemultiple sclerosis

FLI1 MMEL1 LPP DMRTA1 LTBR MEF2C SLC2A4

2.76e-03594937MONDO_0005301
DiseaseTEMPS-A questionnaire

ERBB4 EYA1

2.81e-0325932EFO_0004783
Disease3-hydroxybutyrate measurement

GALNT2 SLC2A4

2.81e-0325932EFO_0010982
DiseaseDeafness

OTOF PAX3

2.81e-0325932C0011053
DiseaseKallmann Syndrome

SOX10 OTX2

3.04e-0326932C0162809
Diseasemyeloperoxidase measurement

GALNT2 ACTA1

3.04e-0326932EFO_0005243

Protein segments in the cluster

PeptideGeneStartEntry
GTSMGGQVAGVYAAY

ABHD6

146

Q9BV23
YTPMSGNQFVYRDGG

ERBB4

1056

Q15303
GTSFQPLMGSAYLYQ

C2orf78

86

A6NCI8
YANNVMSGGTTMYPG

ACTA1

296

P68133
GEPMSYYIASGNLGN

FAT4

2596

Q6V0I7
VPEEYGGLGFSNTMY

ACAD9

111

Q9H845
YANNVLSGGTTMYPG

ACTA2

296

P62736
SSGTYGPQMSQYGPQ

ARID1B

906

Q8NFD5
SNSSQVLMYEGLPGY

ADCY10

506

Q96PN6
NFASNISGGQMYGPG

ANKRD17

2341

O75179
LDGTAYNMGNSFGPY

BCO2

231

Q9BYV7
SSGMEYFNTYGGNPV

ETNPPL

301

Q8TBG4
MSSNSFPYNEQSGGG

AP3B1

1

O00203
GMAEGNFSGSQPYLQ

RAVER2

516

Q9HCJ3
DVFSGSSYPGVQSYM

OPN1LW

206

P04000
DVFSGSSYPGVQSYM

OPN1MW3

206

P0DN78
TVPYMYGFLNGLSQT

OR5M10

146

Q6IEU7
PEYTGLSTTGAMQSY

RFX4

536

Q33E94
AYPLPQASSSYMHGG

HNRNPLL

316

Q8WVV9
DVFSGSSYPGVQSYM

OPN1MW2

206

P0DN77
GSYQQNSMGSYGPQG

ARID1A

786

O14497
SAAKTYYMSGGLQPV

PDHB

126

P11177
TMNVNNPSYGESVYG

COLQ

296

Q9Y215
FYGAITGVYMSPLSN

OR1F12P

251

Q8NHA8
QLHGAMYGSGIYLSP

PARP8

721

Q8N3A8
SPHSTYYMGQSSSGG

KIDINS220

1411

Q9ULH0
YSYAGARAPMGQGFL

LRP10

116

Q7Z4F1
GAYSGLTSGLVPMYV

SLC2A4

146

P14672
YGSPSQYGMAGSYGS

LENG8

111

Q96PV6
QYGMAGSYGSATPQQ

LENG8

116

Q96PV6
YVGGTMVRSGQDPYA

GALNT2

86

Q10471
GGAGTSARVYMQIYG

LOXHD1

826

Q8IVV2
TETANYPTLMGNYNG

BEND2

316

Q8NDZ0
YPTLMGNYNGQNTAS

BEND2

321

Q8NDZ0
GQAPYSYQMQGSSFT

EYA1

176

Q99502
SPHYMAAPSSGQIYG

LPP

231

Q93052
QGMGGYPSAISTTYG

MEF2C

306

Q06413
GISPYFGYSIAGNMD

ITGA6

466

P23229
MNASGSGYPLASLYV

PABPC1L

1

Q4VXU2
LGMPSREYYFNGGSN

MMEL1

256

Q495T6
TYSYTMEGDGAPGPN

ITGB4

681

P16144
TAAASYPMSYGQGGS

OTX1

216

P32242
DVFSGSSYPGVQSYM

OPN1MW

206

P04001
TGYSMDPVTGYQYGQ

PAX3

456

P23760
GSGASFAASMQGLYP

HOXB7

46

P09629
SAYAGQTQYSGMQQP

EYA4

161

O95677
GMQQPAVYTAYSQTG

EYA4

171

O95677
KSSYGGMSQYNCAPG

FOXO1

446

Q12778
YAIGGYGPAHMNSVE

KLHL28

436

Q9NXS3
PMYGSRFGYALSNGT

BBS2

211

Q9BXC9
PYRGGSTNTGKAMTY

COL12A1

511

Q99715
YSSAGRGLSGFMSPY

DMRTA1

441

Q5VZB9
LVGGGESNPMNYNSY

FLI1

91

Q01543
GLLYQFVGATPYTGM

ABCG5

421

Q9H222
YGSAAMSNLGGSPTF

EBF1

491

Q9UH73
SYLNPNSLEGMKGGY

DTHD1

266

Q6ZMT9
NRFPGSSGSNMIYYL

MGARP

36

Q8TDB4
YPRNSTGAYCGMGEN

SLC44A4

66

Q53GD3
SFGMYPSQMNGYGSS

EPS8

11

Q12929
PGATNMIGYMGQTAY

DDX17

701

Q92841
GTMTSKNYPGTYPNH

DCBLD1

51

Q8N8Z6
TNGVVPAGGSYYMIS

SLC12A7

176

Q9Y666
GPYMLASYGQSGLVL

OTOGL

1216

Q3ZCN5
EAGYDSTYGMFQGIP

OTOF

1471

Q9HC10
IATNGVVPAGGSYYM

SLC12A5

176

Q9H2X9
PMTYTQASGYSQGYA

OTX2

176

P32243
PNYMQTGGLEGSHYL

TESMIN

416

Q9Y4I5
SPTGQSPYTYQMHGT

EYA2

126

O00167
PSCHYGNQPSTYGVM

POU1F1

56

P28069
MGGYLFSGSQAPQLS

FBXL12

76

Q9NXK8
VSAQGYNLALMTYPG

TENM1

1621

Q9UKZ4
YGSQTPMYGSGSRTP

SUPT5H

771

O00267
GYNVCVMAYGQTGSG

KIF25

56

Q9UIL4
MGALQYSPISNSQGY

SOX1

251

O00570
NSQGYMSASPSGYGG

SOX1

261

O00570
MGASNGGLLYSQPSF

POU3F2

181

P20265
EYIRFYMGLPGSGNT

NPAP1

846

Q9NZP6
YANNVLSGGTTMYPG

ACTC1

296

P68032
GSHAMYVPGYTANGN

CLCA2

706

Q9UQC9
MYSSFQYRGGPGAGA

ZSWIM5

111

Q9P217
AEMDSTPVGYQYGQG

ZBTB8A

251

Q96BR9
DLSYNSQPFGMQGVG

TLR9

551

Q9NR96
AVYNPAVGYSQGMSD

TBC1D16

521

Q8TBP0
GQASGLYSAFSYMGP

SOX10

416

P56693
GSYSPIDYSDGSGMN

XYLB

206

O75191
PYYMQSSGVSGSQVY

STAM

391

Q92783
GAQLYMIDPSGVSYG

PSMA3

146

P25788
GGTQHIPLYQMSGFY

NT5DC2

161

Q9H857
GMQQEGTPYTGILYA

GART

261

P22102
QGGSPALFTYNGMTD

ZNF469

541

Q96JG9
TGGSMTITGNIYIYN

LTBR

351

P36941
PESGYSMLYSGQKGI

ATP6V0A1

621

Q93050
GPAGQLSYNLMDTYS

PHF8

551

Q9UPP1
TVQQSSFYGYTGMLP

SLC29A4

181

Q7RTT9
AVAQTNSYYGGQTPG

PRSS16

421

Q9NQE7
YSNPSGMSPYASQGF

VPS37A

141

Q8NEZ2
TAMPYLTSYGQLSNG

YTHDF2

81

Q9Y5A9
SNYAYAPSSLGGAMI

YTHDF2

151

Q9Y5A9
SSLAYSPYQSGAGPM

NFKB2

381

Q00653