Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	CBR4 FASN	7.21e-05	2	170	2	GO:0004316
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGAP32 EPS8L2 DOCK10 ARFGEF2 RALGAPA2 NRP1 PREB SLIT2 FAM13A GNB5 HERC2 FGD6 ARHGEF6 TNS3	1.16e-04	507	170	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGAP32 EPS8L2 DOCK10 ARFGEF2 RALGAPA2 NRP1 PREB SLIT2 FAM13A GNB5 HERC2 FGD6 ARHGEF6 TNS3	1.16e-04	507	170	14	GO:0030695
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	TSPAN12 ROCK2 ARHGAP32 SHROOM3 CEACAM5 KIF1A MAP1B RC3H1 DICER1 BRWD3 CHRNB2 NRP1 SLIT2 PLAA SEMA6D NFE2L2 TLR3 PKHD1 SPRED1 FGD6 DKK4 RECK PLXNA2 BRWD1	1.30e-05	1090	172	24	GO:0022603
Domain	PTB	EPS8L2 TNS4 TNS3	3.94e-05	8	169	3	IPR013625
Domain	PTB	EPS8L2 TNS4 TNS3	3.94e-05	8	169	3	PF08416
Domain	WD_REPEATS_1	FBXW10B DCAF6 FBXW10 BRWD3 PREB NBAS PLAA GNB5 HERC2 BRWD1	2.27e-04	278	169	10	PS00678
Domain	-	FBXW10B DCAF6 FBXW10 BRWD3 PREB NBAS PLAA SEMA6D GNB5 PLXNA2 BRWD1	2.32e-04	333	169	11	2.130.10.10
Domain	WD_REPEATS_2	FBXW10B DCAF6 FBXW10 BRWD3 PREB NBAS PLAA GNB5 HERC2 BRWD1	2.34e-04	279	169	10	PS50082
Domain	WD_REPEATS_REGION	FBXW10B DCAF6 FBXW10 BRWD3 PREB NBAS PLAA GNB5 HERC2 BRWD1	2.34e-04	279	169	10	PS50294
Domain	CLCA_chordata	CLCA4 CLCA1	2.43e-04	3	169	2	IPR004727
Domain	CLCA	CLCA4 CLCA1	2.43e-04	3	169	2	IPR013642
Domain	RFX1_trans_act	RFX1 RFX3	2.43e-04	3	169	2	IPR007668
Domain	RFX1_trans_act	RFX1 RFX3	2.43e-04	3	169	2	PF04589
Domain	CLCA	CLCA4 CLCA1	2.43e-04	3	169	2	PF08434
Domain	WD40/YVTN_repeat-like_dom	FBXW10B DCAF6 FBXW10 BRWD3 PREB NBAS PLAA SEMA6D GNB5 PLXNA2 BRWD1	2.44e-04	335	169	11	IPR015943
Domain	ARM-type_fold	RELCH INTS1 ARFGEF2 RALGAPA2 RYR3 PLAA MROH1 AP2A1 ZER1 UNC79 TNPO3	2.70e-04	339	169	11	IPR016024
Domain	MAM_1	NRP1 MAMDC2 MDGA1	3.74e-04	16	169	3	PS00740
Domain	MAM	NRP1 MAMDC2 MDGA1	4.51e-04	17	169	3	SM00137
Domain	-	RC3H2 RC3H1 ZGPAT UNKL	4.59e-04	40	169	4	4.10.1000.10
Domain	G8_domain	CEMIP PKHD1	4.83e-04	4	169	2	IPR019316
Domain	G8	CEMIP PKHD1	4.83e-04	4	169	2	PS51484
Domain	Tensin_PTB	TNS4 TNS3	4.83e-04	4	169	2	IPR033929
Domain	G8	CEMIP PKHD1	4.83e-04	4	169	2	SM01225
Domain	G8	CEMIP PKHD1	4.83e-04	4	169	2	PF10162
Domain	MAM	NRP1 MAMDC2 MDGA1	5.37e-04	18	169	3	PF00629
Domain	MAM_dom	NRP1 MAMDC2 MDGA1	5.37e-04	18	169	3	IPR000998
Domain	MAM_2	NRP1 MAMDC2 MDGA1	5.37e-04	18	169	3	PS50060
Domain	ARM-like	RELCH SETX DOCK10 ARFGEF2 PLAA MROH1 AP2A1 ZER1 TNPO3	8.07e-04	270	169	9	IPR011989
Domain	WD40_repeat	FBXW10B DCAF6 FBXW10 BRWD3 PREB PLAA GNB5 HERC2 BRWD1	8.50e-04	272	169	9	IPR001680
Domain	ZnF_C3H1	RC3H2 RC3H1 ZGPAT UNKL	9.23e-04	48	169	4	SM00356
Domain	zf-CCCH	RC3H2 RC3H1 ZGPAT UNKL	9.98e-04	49	169	4	PF00642
Domain	Pectin_lyas_fold	CEMIP PKHD1	1.19e-03	6	169	2	IPR012334
Domain	-	CEMIP PKHD1	1.19e-03	6	169	2	2.160.20.10
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SESTD1 CLSTN3 DCAF6 KIF1A RBL2 ARFGEF2 ANKRD6 BRWD3 ZNF181 RYR3 AP2M1 LDB1 AP2A1 NFE2L2 TPP1 ZNF655 ZNF451 SPRED1 CTBP1 ZNF841 ZNF83 HERC2 PALS2 RECK ZNF292 BRWD1	1.47e-09	1285	174	26	35914814
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EFCAB5 CCP110 LIMA1 ACACB LAMA1 NSD1 SLIT2 FXR1 DCD TNPO3	3.23e-07	234	174	10	36243803
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	NUP85 COG7 RNF213 AP2M1 PLAA AP2A1 TPP1 PRDX1 TNPO3	3.93e-07	183	174	9	23956138
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RC3H2 SETX NUP85 MAP1B DOCK10 ANKRD50 DICER1 SBNO2 NRP1 CEMIP PREB TPP1 GALNT6 CRYBG3 ZBED1	1.09e-06	650	174	15	38777146
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	ROCK2 CCDC73 ABCA13 LAMA1 DOCK10 RNF213 SERPINA2 TLR3 PKHD1	1.15e-06	208	174	9	33230847
Pubmed	A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins.	FAM184B INTS1 UNC79	1.22e-06	5	174	3	16807365
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CCP110 ARHGAP32 LIMA1 SHROOM3 SETX AFTPH MAP1B FXR1 FAM13A STARD9 TET1 OTUD7A MPHOSPH9 CRYBG3 FGD6 TNPO3 TNS3	1.73e-06	861	174	17	36931259
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	ROCK2 KIF1A MAP1B NSF GRID2 FASN AP2M1 AP2A1 GNB5 PRDX1 CTBP1 LRRC7 HSD17B10 HDLBP	3.31e-06	621	174	14	22794259
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TCF7L2 ZNF195 BTBD9 RFX1 RFX3 ZNF786 ZGPAT LDB1 NFE2L2 ZNF655 ZNF451 PLXNA2 KDM4B ZNF681 ZNF239 ZNF292	3.41e-06	808	174	16	20412781
Pubmed	Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.	RC3H2 RC3H1 PTPRC	4.24e-06	7	174	3	34811541
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ROCK2 RELCH ARHGAP32 ARFGEF2 SLC6A15 ITGA3 RALGAPA2 CDCP1 PREB AP2M1 FGD6 PLXNA2 TNS3	6.49e-06	569	174	13	30639242
Pubmed	Tagging genes with cassette-exchange sites.	RELCH LIMA1 NSF ARFGEF2 PLAA ZNF655 TET1 PRDX1 ZNF681 ZNF292	8.03e-06	335	174	10	15741177
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	SLF1 RBL2 CHAF1A ZNF195 ZNF407 ANKRD6 RFX3 PREB LDB1 ZNF35 NFE2L2 CBFA2T2 ZNF451 CTBP1 KDM4B ZNF292	9.51e-06	877	174	16	20211142
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ROCK2 ARHGAP32 ACACB SLC6A15 ANKRD50 RALGAPA2 SEMA6D AP2A1 CIBAR1 CTBP1 PALS2	9.89e-06	421	174	11	36976175
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	NRP1 SLIT2 SEMA6D PLXNA2	1.13e-05	28	174	4	18617019
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CDK8 DCAF6 SHROOM3 TCF7L2 KIF1A MAP1B CDK19 RNF213 BTBD9 BRWD3 SBNO2 NRP1 LDB1 FAM13A CBFA2T2 CTBP1 LRRC7 PALS2 CSMD1 RECK KDM4B	1.92e-05	1489	174	21	28611215
Pubmed	A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.	TNS4 TNS3	2.49e-05	2	174	2	17643115
Pubmed	Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.	CDK8 CDK19	2.49e-05	2	174	2	35181333
Pubmed	Regulatory functions of the Mediator kinases CDK8 and CDK19.	CDK8 CDK19	2.49e-05	2	174	2	30585107
Pubmed	HIV Transcription Is Independent of Mediator Kinases.	CDK8 CDK19	2.49e-05	2	174	2	31044597
Pubmed	Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells.	NFE2L2 PRDX1	2.49e-05	2	174	2	31901729
Pubmed	Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells.	TCF7L2 CTBP1	2.49e-05	2	174	2	25483087
Pubmed	Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif.	RBBP8 CTBP1	2.49e-05	2	174	2	9535825
Pubmed	Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.	CDK8 CDK19	2.49e-05	2	174	2	32560467
Pubmed	A tumor-suppressing function in the epithelial adhesion protein Trask.	CDCP1 CHRNB2	2.49e-05	2	174	2	21706059
Pubmed	A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor.	RBBP8 RBL2	2.49e-05	2	174	2	10449734
Pubmed	The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis.	CLCA4 CLCA1	2.49e-05	2	174	2	15490240
Pubmed	RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction.	RFX1 RFX3	2.49e-05	2	174	2	29317724
Pubmed	[Mechanisms of transcriptional regulation upon protein phosphorylation by mediator complexes].	CDK8 CDK19	2.49e-05	2	174	2	20408451
Pubmed	TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription.	TCF7L2 CTBP1	2.49e-05	2	174	2	16547505
Pubmed	Mediator kinase inhibition further activates super-enhancer-associated genes in AML.	CDK8 CDK19	2.49e-05	2	174	2	26416749
Pubmed	CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.	CDK8 CDK19	2.49e-05	2	174	2	28855340
Pubmed	Evi-2, a common integration site involved in murine myeloid leukemogenesis.	EVI2A EVI2B	2.49e-05	2	174	2	2167436
Pubmed	Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.	CDK8 CDK19	2.49e-05	2	174	2	27678455
Pubmed	Identification and characterization of transcripts from the neurofibromatosis 1 region: the sequence and genomic structure of EVI2 and mapping of other transcripts.	EVI2A EVI2B	2.49e-05	2	174	2	2117566
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	2.49e-05	2	174	2	31400758
Pubmed	CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.	CDK8 CDK19	2.49e-05	2	174	2	36006697
Pubmed	CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.	CDK8 CDK19	2.49e-05	2	174	2	37378433
Pubmed	cDNA sequence and genomic structure of EV12B, a gene lying within an intron of the neurofibromatosis type 1 gene.	EVI2A EVI2B	2.49e-05	2	174	2	1903357
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	2.49e-05	2	174	2	37450367
Pubmed	Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation.	NFE2L2 TET1	2.49e-05	2	174	2	24743738
Pubmed	Structure of human Roquin-2 and its complex with constitutive-decay element RNA.	RC3H2 RC3H1	2.49e-05	2	174	2	26249698
Pubmed	Elevated peroxiredoxin 1, but not NF-E2-related factor 2, is an independent prognostic factor for disease recurrence and reduced survival in stage I non-small cell lung cancer.	NFE2L2 PRDX1	2.49e-05	2	174	2	17606720
Pubmed	Identification of target genes for the CDK subunits of the Mediator complex.	CDK8 CDK19	2.49e-05	2	174	2	22117896
Pubmed	Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology.	NFE2L2 PRDX1	2.49e-05	2	174	2	17234762
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	NRP1 SEMA6D PLXNA2	2.62e-05	12	174	3	24179230
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ROCK2 SESTD1 ARHGAP32 LIMA1 SHROOM3 NSF NSD1 BTBD9 FXR1 LDB1 AP2A1 PRDX1 CTBP1 LRRC7 HERC2 UNC79	2.97e-05	963	174	16	28671696
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	LIMA1 MAP1B NSF FASN FXR1 AP2A1 PRDX1 HSD17B10 HDLBP	3.00e-05	312	174	9	37120454
Pubmed	Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2.	ACACB FASN NFE2L2	3.39e-05	13	174	3	36421460
Pubmed	EphrinA2 regulates clathrin mediated KSHV endocytosis in fibroblast cells by coordinating integrin-associated signaling and c-Cbl directed polyubiquitination.	ITGA3 AP2M1 AP2A1	3.39e-05	13	174	3	23874206
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ROCK2 LIMA1 AFTPH RBBP8 CHAF1A ARFGEF2 RFX1 FASN PTPRC FAM13A CBFA2T2 ARHGEF6 KDM4B HDLBP	3.84e-05	774	174	14	15302935
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ROCK2 EFCAB5 FAM184B LIMA1 NUP85 ACACB PCDHGB7 MAP1B RBBP8 CHAF1A LARP7 FASN AP2M1 FXR1 AP2A1 STARD9 PRDX1 PKHD1 PLXNA2 ZNF292	3.88e-05	1442	174	20	35575683
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ROCK2 CCP110 ARHGAP32 RC3H1 RNF213 ZNF407 BTBD9 ANKRD6 RALGAPA2 AP2M1 FGD6	4.20e-05	493	174	11	15368895
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CLSTN3 CDK19 DOCK10 EPG5 SEMA6D MROH1 STARD9 ZNF451 LRRC7 PLXNA2	4.24e-05	407	174	10	12693553
Pubmed	Functional proteomics mapping of a human signaling pathway.	ARFGEF2 RFX1 EPG5 PTPRC LDB1 AP2A1 ZNF451 SPRED1 ZNF83 HERC2 TNPO3 HDLBP	4.68e-05	591	174	12	15231748
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SDE2 TCF7L2 SETX CHAF1A INTS1 NSD1 RFX1 ZNF451 HERC2 KDM4B ZNF292 BRWD1	6.13e-05	608	174	12	36089195
Pubmed	PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.	NSF AP2M1 AP2A1	6.57e-05	16	174	3	16055064
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	NRP1 SEMA6D PLXNA2	6.57e-05	16	174	3	22632726
Pubmed	HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation.	AP2M1 CLCA1 AP2A1	6.57e-05	16	174	3	21762802
Pubmed	Involvement of RFX proteins in transcriptional activation from a Ras-responsive enhancer element.	RFX1 RFX3	7.44e-05	3	174	2	15024578
Pubmed	Role for RFX transcription factors in non-neuronal cell-specific inactivation of the microtubule-associated protein MAP1A promoter.	RFX1 RFX3	7.44e-05	3	174	2	12411430
Pubmed	Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.	AP2M1 AP2A1	7.44e-05	3	174	2	35014951
Pubmed	A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.	AP2M1 AP2A1	7.44e-05	3	174	2	18032517
Pubmed	RFX transcription factors are essential for hearing in mice.	RFX1 RFX3	7.44e-05	3	174	2	26469318
Pubmed	Competition model for upregulation of the major histocompatibility complex class II-associated invariant chain by human immunodeficiency virus type 1 Nef.	AP2M1 AP2A1	7.44e-05	3	174	2	18524831
Pubmed	Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.	CDK8 CDK19	7.44e-05	3	174	2	26002960
Pubmed	The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene.	EVI2A EVI2B	7.44e-05	3	174	2	1899288
Pubmed	Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains.	RFX1 RFX3	7.44e-05	3	174	2	10330134
Pubmed	Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.	RC3H2 RC3H1	7.44e-05	3	174	2	23583642
Pubmed	Ciliogenic RFX transcription factors regulate FGF1 gene promoter.	RFX1 RFX3	7.44e-05	3	174	2	22415835
Pubmed	Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system.	CLCA4 CLCA1	7.44e-05	3	174	2	19210762
Pubmed	Roquin Paralogs Differentially Regulate Functional NKT Cell Subsets.	RC3H2 RC3H1	7.44e-05	3	174	2	28188245
Pubmed	Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation.	RFX1 RFX3	7.44e-05	3	174	2	12403718
Pubmed	Axonal pathology in hPSC-based models of Parkinson's disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus.	MAP1B NFE2L2	7.44e-05	3	174	2	31235589
Pubmed	TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells.	TCF7L2 DKK4	7.44e-05	3	174	2	28450117
Pubmed	Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea.	CLCA4 CLCA1	7.44e-05	3	174	2	10437792
Pubmed	Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.	ACACB FASN	7.44e-05	3	174	2	18455495
Pubmed	Murine homologue of the human KIAA1199 is implicated in hyaluronan binding and depolymerization.	CEMIP AP2A1	7.44e-05	3	174	2	24251095
Pubmed	Interplay of RFX transcription factors 1, 2 and 3 in motile ciliogenesis.	RFX1 RFX3	7.44e-05	3	174	2	32725242
Pubmed	Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.	RC3H2 RC3H1	7.44e-05	3	174	2	25026077
Pubmed	Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage.	RBBP8 CTBP1	7.44e-05	3	174	2	10196224
Pubmed	A de novo Alu insertion results in neurofibromatosis type 1.	EVI2A EVI2B	7.44e-05	3	174	2	1719426
Pubmed	Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9.	CDK8 CDK19	7.44e-05	3	174	2	28151579
Pubmed	Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung.	AP2M1 FXR1	7.44e-05	3	174	2	17290396
Pubmed	Differential induction of nuclear factor-like 2 signature genes with toll-like receptor stimulation.	NFE2L2 PRDX1	7.44e-05	3	174	2	30894323
Pubmed	Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.	NRP1 PLXNA2	7.44e-05	3	174	2	23104057
Pubmed	Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.	RC3H2 RC3H1	7.44e-05	3	174	2	30232334
Pubmed	Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1.	FXR1 ZNF451	7.44e-05	3	174	2	36209117
Pubmed	Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2.	DICER1 NFE2L2	7.44e-05	3	174	2	32737764
Pubmed	FXR1 facilitates axitinib resistance in clear cell renal cell carcinoma via regulating KEAP1/Nrf2 signaling pathway.	FXR1 NFE2L2	7.44e-05	3	174	2	36730618
Pubmed	KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization.	CEMIP AP2A1	7.44e-05	3	174	2	23509262
Pubmed	Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.	CLCA4 CLCA1	7.44e-05	3	174	2	16569774
Pubmed	Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis.	SLIT2 TLR3	7.44e-05	3	174	2	32999457
Pubmed	A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations.	EVI2A EVI2B	7.44e-05	3	174	2	2114220
Pubmed	RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.	RFX1 RFX3	7.44e-05	3	174	2	8289803
Pubmed	HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells.	TCF7L2 CTBP1	7.44e-05	3	174	2	12711682
Pubmed	The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling.	RBBP8 CTBP1	7.44e-05	3	174	2	11313276
Pubmed	GlcNAc-transferase V and core 2 GlcNAc-transferase expression in the developing mouse embryo.	GCNT1 MGAT5	7.44e-05	3	174	2	8720078
Pubmed	Identification of reliable reference genes for qRT-PCR studies of the developing mouse mammary gland.	PRDX1 CTBP1	7.44e-05	3	174	2	27752147
Pubmed	Prx I suppresses K-ras-driven lung tumorigenesis by opposing redox-sensitive ERK/cyclin D1 pathway.	NFE2L2 PRDX1	7.44e-05	3	174	2	23186333
Cytoband	7p12.3	ABCA13 UPP1 TNS3	7.82e-05	22	174	3	7p12.3
Cytoband	15q14-q15	CCNDBP1 RYR3	1.42e-04	5	174	2	15q14-q15
Cytoband	7q31.31	TSPAN12 CPED1	2.12e-04	6	174	2	7q31.31
GeneFamily	Zinc fingers CCCH-type	RC3H2 RC3H1 ZGPAT UNKL	8.24e-05	35	120	4	73
GeneFamily	Chloride channel accessory	CLCA4 CLCA1	2.60e-04	4	120	2	867
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF142 ZNF195 ZNF407 ZNF233 ZNF786 ZNF181 ZNF35 ZNF655 ZNF451 ZNF841 ZNF83 ZNF681 ZNF239 ZNF292	2.92e-04	718	120	14	28
GeneFamily	WD repeat domain containing	FBXW10B DCAF6 FBXW10 BRWD3 PREB PLAA GNB5 BRWD1	3.63e-04	262	120	8	362
GeneFamily	Regulatory factor X family	RFX1 RFX3	1.19e-03	8	120	2	1153
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ICOSLG IL13RA1 CEACAM5 EVI2B ITGA3 CDCP1 NRP1 PTPRC TLR3	1.26e-03	394	120	9	471
GeneFamily	Short chain dehydrogenase/reductase superfamily	SDR42E1 CBR4 FASN HSD17B10	1.64e-03	76	120	4	743
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	2.31e-03	11	120	2	559
Coexpression	GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP	RELCH RALGAPA2 FXR1 MROH1 ZNF655 ETAA1 UNKL PALS2 ARHGEF6	7.03e-06	200	171	9	M8491
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CDK8 ROCK2 TCF7L2 SETX MAP1B CDK19 GCNT1 DICER1 CEMIP SLIT2 NBAS FXR1 MGAT5 ZNF451 MPHOSPH9 CRYBG3 PALS2 ZNF292	1.34e-05	856	171	18	M4500
ToppCell	15-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	CCP110 ARHGAP32 HAGHL ABCA13 CDHR3 STMND1 RFX3 FHAD1 VWA3B	6.59e-08	192	173	9	9cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	DOCK10 NSD1 ARFGEF2 RNF213 NBAS PTPRC ZNF841 ZNF292	8.46e-07	191	173	8	9454f642c3621370fa23640b631301346b300950
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 RBBP8 RNF213 CASR ITGA3 CDCP1 PKHD1 ZNF83	9.89e-07	195	173	8	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 RBBP8 RNF213 CASR ITGA3 CDCP1 PKHD1 ZNF83	9.89e-07	195	173	8	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ROCK2 SETX SLF1 RNF213 RALGAPA2 NRP1 FGD6 BRWD1	1.20e-06	200	173	8	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MAP1B ANKRD50 SLIT2 FHAD1 SEMA6D SPRED1 MDGA1 TNS3	1.20e-06	200	173	8	d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK10 EVI2A EVI2B PTPRC TLR3 PALS2 RAB32	8.13e-06	185	173	7	ed7b26bdebfd0df2b4f5020a855a052d94ae7219
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IL13RA1 CDHR3 DOCK10 MYRFL SLIT2 SEMA6D MDGA1	8.42e-06	186	173	7	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CLSTN3 MAP1B NSF SLC6A15 CHRNB2 LRRC7 UNC79	8.42e-06	186	173	7	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 CASR ITGA3 SEMA6D PKHD1 UPP1 ZNF83	8.72e-06	187	173	7	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	DOCK10 RNF213 ZNF407 BTBD9 EPG5 PTPRC FAM13A	9.02e-06	188	173	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IL13RA1 CDHR3 DOCK10 MYRFL SLIT2 SEMA6D MDGA1	9.02e-06	188	173	7	4544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 RBBP8 LAMA1 NRP1 PKHD1 PALS2 TNS3	9.02e-06	188	173	7	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 LAMA1 CASR CDCP1 SEMA6D NFE2L2 PKHD1	9.34e-06	189	173	7	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	Epithelial_cells-Ciliated_cells-A\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	MAP1B HAGHL CDHR3 STMND1 RFX3 FHAD1 VWA3B	9.67e-06	190	173	7	549d813a8f23b175875e53347928941f143e236c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EFCAB5 SESTD1 LAMA1 CASR ITGA3 NRP1 PKHD1	1.00e-05	191	173	7	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EFCAB5 SESTD1 LAMA1 CASR ITGA3 NRP1 PKHD1	1.00e-05	191	173	7	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 RBBP8 CASR ITGA3 CDCP1 PKHD1 ZNF83	1.07e-05	193	173	7	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 RBBP8 CASR ITGA3 CDCP1 PKHD1 ZNF83	1.07e-05	193	173	7	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 RBBP8 RNF213 CASR ITGA3 PKHD1 ZNF83	1.11e-05	194	173	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TSPAN12 LIMA1 ABCA13 GTSF1L PLD5 ARHGEF6	1.24e-05	131	173	6	9ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 RBBP8 SLC6A15 ITGA3 CEMIP TNS4 CSMD1	1.31e-05	199	173	7	94a7867e800df352731796de8c24cba133c29622
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	ROCK2 LIMA1 SHROOM3 MAP1B LARP7 ZNF292 BRWD1	1.31e-05	199	173	7	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TSPAN12 ROCK2 SETX RNF213 RALGAPA2 NRP1 DISP1	1.35e-05	200	173	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IL13RA1 CDHR3 DOCK10 MYRFL SLIT2 SEMA6D MDGA1	1.35e-05	200	173	7	ca5401b76ab014080914bf78042d368cf318effa
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA4 LIMA1 ABCA13 RBBP8 RNF213 RALGAPA2 DKK4	1.35e-05	200	173	7	0f6620a5baace704518d42fa2f3f90751240f7dd
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	CCP110 GLT1D1 CHAF1A ARFGEF2 FXR1 MGAT5 HDLBP	1.35e-05	200	173	7	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TSPAN12 ROCK2 SETX RNF213 RALGAPA2 NRP1 DISP1	1.35e-05	200	173	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IL13RA1 CDHR3 DOCK10 MYRFL SLIT2 SEMA6D MDGA1	1.35e-05	200	173	7	70c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IL13RA1 CDHR3 DOCK10 MYRFL SLIT2 SEMA6D MDGA1	1.35e-05	200	173	7	40286010bd17cf9e34ecd5440953b072ebfae208
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	EFCAB5 MAP1B SLIT2 FHAD1 SEMA6D STARD9 TNS3	1.35e-05	200	173	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	EFCAB5 CDHR3 STMND1 FHAD1 VWA3B UNC79	3.00e-05	153	173	6	fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	EFCAB5 CDHR3 STMND1 FHAD1 VWA3B UNC79	3.00e-05	153	173	6	2482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 EVI2A EVI2B PTPRC RAB32 ARHGEF6	3.59e-05	158	173	6	e0b862e4b9ebaa12869640b5d18d5fa852861bef
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AFTPH MGAT5 SEMA6D FAM13A GALNT6 ZNF681	4.27e-05	163	173	6	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	droplet-Limb_Muscle-nan-3m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVI2A GCNT1 ZNF35 TNS4 GALNT6 RAB32	4.73e-05	166	173	6	0a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RC3H2 CCDC73 ITGA3 FXR1 RAB32 ALPK2	4.89e-05	167	173	6	528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RC3H2 CCDC73 ITGA3 FXR1 RAB32 ALPK2	4.89e-05	167	173	6	a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCell	droplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICOSLG CDHR3 DOCK10 EVI2A EVI2B TLR3	5.05e-05	168	173	6	ce5e92a1df3acfa5cd8d5a134e4af231dc592a13
ToppCell	droplet-Liver-Npc-18m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ICOSLG CDHR3 DOCK10 EVI2A EVI2B TLR3	5.05e-05	168	173	6	22c89d4eb44573f6301069ec7ca7cbd0dd958403
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TSPAN12 LAMA1 ATF7IP2 PLD5 ARHGEF6	5.12e-05	103	173	5	780a94c27ac3eb138a9f284251ae094d3e97ce71
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B ABCA13 RYR3 PKHD1 PLD5 UNC79	5.22e-05	169	173	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLT1D1 EVI2A EVI2B PTPRC SLC24A4 RAB32	5.40e-05	170	173	6	3e52d40b0c36ab5b627a2dad025248901af8a320
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 SLC6A15 NRP1 CEMIP TNS4 DISP1	5.40e-05	170	173	6	a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TSPAN12 SLC6A15 NRP1 CEMIP TNS4 DISP1	5.40e-05	170	173	6	b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 RBBP8 LAMA1 ITGA3 PKHD1 ALPK2	5.76e-05	172	173	6	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B ABCA13 CDHR3 RFX3 CFAP65 FHAD1	5.76e-05	172	173	6	187ae91148d293537afc77e10da2b64302322224
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLIT2 MROH1 ZNF35 UPP1 PALS2 MDGA1	5.76e-05	172	173	6	e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 RBBP8 LAMA1 ITGA3 PKHD1 ALPK2	5.76e-05	172	173	6	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 CDHR3 RFX3 CFAP65 FHAD1 VWA3B	5.95e-05	173	173	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	facs-Aorta-Heart-3m-Myeloid\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNDBP1 DOCK10 EVI2B PTPRC RAB32 ARHGEF6	5.95e-05	173	173	6	513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	RELCH SDE2 CLCA4 NFE2L2 CRYBG3 PLXNA2	6.34e-05	175	173	6	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	droplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 RELCH EVI2B UBE3D AP5M1 ZNF239	6.54e-05	176	173	6	8e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCell	facs-Lung-EPCAM-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 EVI2A EVI2B PTPRC RAB32 ARHGEF6	6.75e-05	177	173	6	7bc92314b22a876296a4e2db51e7fb0fdfd69379
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	NSD1 RNF213 ZNF407 NBAS PTPRC ZNF841	6.75e-05	177	173	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8L2 SHROOM3 CEACAM5 PKHD1 PLD5 TNS3	6.75e-05	177	173	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM184B LIMA1 SHROOM3 DOCK10 SLIT2 CRYBG3	7.18e-05	179	173	6	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK10 EVI2A EVI2B PTPRC RAB32 ARHGEF6	7.18e-05	179	173	6	33ed9270d257895ff3b40df2c1af878119c9f492
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCP110 CDHR3 STMND1 CFAP65 FHAD1 GTSF1L	7.18e-05	179	173	6	d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCP110 CDHR3 STMND1 CFAP65 FHAD1 GTSF1L	7.18e-05	179	173	6	8a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK10 EVI2B PTPRC TLR3 RAB32 ARHGEF6	7.18e-05	179	173	6	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	RELCH ARHGAP32 LIMA1 SHROOM3 TCF7L2 RBBP8	7.64e-05	181	173	6	8fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCell	facs-Lung-EPCAM-24m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 EVI2A EVI2B PTPRC TLR3 RAB32	7.87e-05	182	173	6	9465238ac806fce46dfe1a141e83893f23eb4afb
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLSTN3 LDB1 GALNT6 ZBED1 RAB32 ARHGEF6	7.87e-05	182	173	6	4cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 MAP1B ABCA13 CASR NRP1 TLR3	7.87e-05	182	173	6	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	FAM184B LIMA1 SHROOM3 DOCK10 SLIT2 CRYBG3	8.11e-05	183	173	6	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 EVI2A EVI2B TLR3 PALS2 RAB32	8.11e-05	183	173	6	107cc756c45d6e92181659868d91188814dae66d
ToppCell	Nasal_Brush-Immune-Dendritic_cells\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DOCK10 EVI2A EVI2B PTPRC SLC24A4 ALPK2	8.11e-05	183	173	6	b1daec831990a53e846c089cebfcf4f8440820e4
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ABCA13 CDHR3 NRP1 PKHD1 PALS2 ALPK2	8.36e-05	184	173	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	droplet-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 NRP1 CLCA1 GIMAP8 UPP1 PLXNA2	8.36e-05	184	173	6	fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 LAMA1 RYR3 PKHD1 CSMD1 UNC79	8.36e-05	184	173	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN12 NRP1 CLCA1 GIMAP8 UPP1 PLXNA2	8.36e-05	184	173	6	ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8L2 GRID2 RYR3 CEMIP SLIT2 PLD5	8.36e-05	184	173	6	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 LAMA1 RYR3 PKHD1 CSMD1 UNC79	8.36e-05	184	173	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 LAMA1 RYR3 PKHD1 CSMD1 UNC79	8.36e-05	184	173	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 NRP1 CLCA1 GIMAP8 UPP1 PLXNA2	8.36e-05	184	173	6	1d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCell	droplet-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN12 NRP1 CLCA1 GIMAP8 UPP1 PLXNA2	8.36e-05	184	173	6	76caad53d55fff5acca27bf190a6de7b27437d9f
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN12 NRP1 CLCA1 GIMAP8 UPP1 PLXNA2	8.36e-05	184	173	6	1fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSPAN12 NRP1 CLCA1 GIMAP8 UPP1 PLXNA2	8.36e-05	184	173	6	2467207aaea307873ab286f89cfc7668a227a694
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TSPAN12 PCDHGB7 KIF1A BTBD9 STARD9 OTUD7A	8.61e-05	185	173	6	0094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP1B CDHR3 STMND1 CFAP65 FHAD1 VWA3B	8.61e-05	185	173	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	15-Airway-Epithelial-Multiciliated_cell\|Airway / Age, Tissue, Lineage and Cell class	HAGHL CDHR3 STMND1 CFAP65 FHAD1 VWA3B	8.61e-05	185	173	6	0998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GCNT1 CPED1 NRP1 MGAT5 MAMDC2 SPRED1	8.61e-05	185	173	6	8207f9eff113eed429e961748c6b17d672a13b33
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SHROOM3 NRP1 FAM13A CSMD1 PLXNA2 TNS3	8.87e-05	186	173	6	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	Ciliated-cil-1\|World / Class top	CDHR3 STMND1 CFAP65 FHAD1 SLC24A4 GTSF1L	8.87e-05	186	173	6	283de646a0e8a322c42a714ae19db9918011146e
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DOCK10 RNF213 NBAS PTPRC ZNF83 ZNF292	8.87e-05	186	173	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	Anterior_Cingulate_gyrus_(CgG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRID2 MYRFL ANKRD50 ANKRD6 NRP1 PALS2	8.87e-05	186	173	6	32af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SHROOM3 NRP1 FAM13A CSMD1 PLXNA2 TNS3	8.87e-05	186	173	6	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 LAMA1 NRP1 PKHD1 PALS2 TNS3	8.87e-05	186	173	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 CDHR3 NRP1 PKHD1 PALS2 ALPK2	8.87e-05	186	173	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Ciliated-cil-2\|World / Class top	CDHR3 STMND1 CFAP65 FHAD1 SLC24A4 GTSF1L	9.14e-05	187	173	6	e2e58ba039b5355c03c3b448e750aa37b0ea6913
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CLSTN3 MAP1B GLT1D1 CHRNB2 MGAT5 UNC79	9.14e-05	187	173	6	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 LAMA1 NRP1 PKHD1 PALS2 TNS3	9.14e-05	187	173	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NRP1 PKHD1 ZNF83 PALS2 ALPK2	9.14e-05	187	173	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RC3H1 NRP1 GIMAP8 LDB1 SEMA6D MPHOSPH9	9.14e-05	187	173	6	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RC3H1 NRP1 GIMAP8 LDB1 SEMA6D MPHOSPH9	9.14e-05	187	173	6	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	Ciliated\|World / Class top	CDHR3 STMND1 CFAP65 FHAD1 SLC24A4 GTSF1L	9.41e-05	188	173	6	cc9178361360b5800f96516ed6a65089c144b1ce
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	SLF1 MAP1B CDHR3 STMND1 CFAP65 FHAD1	9.41e-05	188	173	6	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	SHROOM3 RBBP8 LAMA1 CASR CDCP1 PKHD1	9.41e-05	188	173	6	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8L2 SHROOM3 ACACB ABCA13 CASR SLIT2	9.41e-05	188	173	6	14e120b20e76baa07b6510a94f0c2dcdfdd52357
Disease	Intellectual Disability	CDK8 ZNF142 MAP1B NSF LAMA1 NSD1 BRWD3 LARP7 FASN AP2M1 TPP1 ZNF292	1.13e-05	447	169	12	C3714756
Disease	developmental and epileptic encephalopathy 87 (implicated_via_orthology)	CDK8 CDK19	3.26e-05	2	169	2	DOID:0112221 (implicated_via_orthology)
Disease	Schizophrenia	ARHGAP32 TCF7L2 ABCA13 LAMA1 BTBD9 DICER1 CHRNB2 SBNO2 CFAP65 PLAA TET1 TLR3 CSMD1 MDGA1 DKK4 PLXNA2	5.17e-05	883	169	16	C0036341
Disease	Colorectal Carcinoma	RELCH CLSTN3 TCF7L2 MAP1B ABCA13 LAMA1 GRID2 LDB1 GNB5 ETAA1 PKHD1 CTBP1 TNS4 ZNF292	5.65e-05	702	169	14	C0009402
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	AP2M1 KDM4B ZNF292	1.18e-04	17	169	3	DOID:0060307 (is_implicated_in)
Disease	Global developmental delay	CDK8 ZNF142 NSF INTS1 NBAS AP2M1	1.21e-04	133	169	6	C0557874
Disease	response to radiation	BRWD3 EPG5 PTPRC UBE3D CSMD1	1.55e-04	88	169	5	GO_0009314
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	TCF7L2 CCDC73 DOCK10 ZNF407 SLIT2 FXR1 MGAT5 SEMA6D FAM13A CTBP1 UNC79 PLXNA2 KDM4B BRWD1	2.23e-04	801	169	14	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Left Ventricle Remodeling	ROCK2 TCF7L2 NFE2L2	2.28e-04	21	169	3	C0600520
Disease	Ventricular Remodeling	ROCK2 TCF7L2 NFE2L2	2.28e-04	21	169	3	C0600519
Disease	marginal zone B-cell lymphoma, systemic lupus erythematosus	STMND1 MGAT5	3.22e-04	5	169	2	EFO_1000630, MONDO_0007915
Disease	muscular disease (implicated_via_orthology)	ACACB FASN	3.22e-04	5	169	2	DOID:0080000 (implicated_via_orthology)
Disease	biological sex	TCF7L2 NRP1 FXR1 SEMA6D PKHD1 LRRC7 PALS2	3.78e-04	230	169	7	PATO_0000047
Disease	blood rubidium measurement	ABCA13 ARFGEF2 MDGA1	4.36e-04	26	169	3	EFO_0021529
Disease	periventricular nodular heterotopia (is_implicated_in)	MAP1B ARFGEF2	4.82e-04	6	169	2	DOID:0050454 (is_implicated_in)
Disease	coronary artery disease	CDK8 SHROOM3 TCF7L2 KIF1A MAP1B ARFGEF2 RNF213 ANKRD50 ANKRD6 SERPINA2 EPG5 NRP1 PKHD1 LRRC7 FGD6 KDM4B TNS3	5.26e-04	1194	169	17	EFO_0001645
Disease	amino acid measurement	CDK8 SETX ACACB COG7 RYR3 SLIT2 NBAS OR4S1 ATF7IP2 CSMD1 PLXNA2 TRIM51G	5.65e-04	678	169	12	EFO_0005134
Disease	parental longevity	SHROOM3 RFX3 RYR3 NRP1 CEMIP MGAT5 SEMA6D OTUD7A ZER1 CSMD1	5.91e-04	494	169	10	EFO_0007796
Disease	sugar consumption measurement	TCF7L2 NBAS PKHD1 CSMD1 PLXNA2	6.51e-04	120	169	5	EFO_0010158
Disease	Periventricular Nodular Heterotopia	MAP1B ARFGEF2	6.72e-04	7	169	2	C1868720
Disease	uridine measurement	SLIT2 UPP1 CSMD1	8.10e-04	32	169	3	EFO_0010546
Disease	hair colour measurement	SHROOM3 DOCK10 SLC6A15 EPG5 SEMA6D FAM13A SLC24A4 PKHD1 ZNF83 HERC2 PALS2	8.79e-04	615	169	11	EFO_0007822
Disease	Abnormality of the skeletal system	INTS1 ZNF292	8.93e-04	8	169	2	C4021790
Disease	Ataxias, Hereditary	SETX TPP1	8.93e-04	8	169	2	C0004138
Disease	coronary aneurysm	FHAD1 CSMD1 MDGA1	1.06e-03	35	169	3	EFO_1000881
Disease	smoking status measurement	NSF ZNF407 SLC6A15 GRID2 RFX3 SLIT2 SEMA6D ZNF655 PKHD1 PLD5 PALS2 MDGA1 UNC79 PLXNA2 KDM4B BRWD1	1.07e-03	1160	169	16	EFO_0006527
Disease	Alzheimer disease, fasting blood glucose measurement	TCF7L2 OR4S1	1.14e-03	9	169	2	EFO_0004465, MONDO_0004975
Disease	phosphatidylcholine 32:1 measurement	F9 ATF7IP2 CSMD1	1.34e-03	38	169	3	EFO_0010373
Disease	postburn hypertrophic scarring severity measurement	ATF7IP2 CSMD1	1.42e-03	10	169	2	EFO_0007747
Disease	neuroblastoma (is_implicated_in)	CHAF1A NSD1	1.42e-03	10	169	2	DOID:769 (is_implicated_in)
Disease	chronic obstructive pulmonary disease, chronic bronchitis	FAM13A CSMD1	1.42e-03	10	169	2	EFO_0000341, EFO_0006505
Disease	pigmentation disease (is_implicated_in)	SLC24A4 HERC2	1.73e-03	11	169	2	DOID:10123 (is_implicated_in)
Disease	eye color	ARHGAP32 SLC24A4 HERC2 CSMD1	1.81e-03	90	169	4	EFO_0003949
Disease	cortical thickness	SHROOM3 FBXW10 TCF7L2 NSF CHAF1A LAMA1 ARFGEF2 SLC6A15 CPED1 NRP1 SLIT2 PKHD1 FIGLA PLXNA2 KDM4B	1.92e-03	1113	169	15	EFO_0004840
Disease	Ischemic stroke, coronary artery disease	NSF RNF213 EPG5 FGD6	1.96e-03	92	169	4	EFO_0001645, HP_0002140
Disease	hair colour measurement, hair morphology measurement	SLC24A4 HERC2	2.07e-03	12	169	2	EFO_0007821, EFO_0007822
Disease	Oligospermia	DICER1 BRWD1	2.07e-03	12	169	2	C0028960
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	PKHD1 CSMD1	2.44e-03	13	169	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	Alzheimer disease, APOE carrier status	SETX PMS2CL NBAS KDM4B	2.47e-03	98	169	4	EFO_0007659, MONDO_0004975
Disease	disease progression measurement, Crohn's disease	CDHR3 NRP1 CSMD1	2.49e-03	47	169	3	EFO_0000384, EFO_0008336
Disease	schizophrenia, anorexia nervosa	FXR1 SEMA6D MPHOSPH9	2.64e-03	48	169	3	MONDO_0005090, MONDO_0005351
Disease	triacylglycerol 48:4 measurement	F9 PLD5	2.84e-03	14	169	2	EFO_0010407
Disease	sitting height ratio	TCF7L2 NSD1 MDGA1	3.14e-03	51	169	3	EFO_0007118
Disease	Generalized hypotonia	CDK8 AP2M1	3.26e-03	15	169	2	C1858120
Disease	periprosthetic osteolysis, disease progression measurement	CEMIP OTUD7A	3.26e-03	15	169	2	EFO_0008336, EFO_0009761
Disease	Uveal Melanoma	MGAT5 GNB5 HERC2	3.50e-03	53	169	3	EFO_1000616
Disease	Autistic Disorder	KIF1A NSD1 CHRNB2 PLD5 ZNF292 HDLBP	4.04e-03	261	169	6	C0004352
Disease	R-6-hydroxywarfarin measurement	SHROOM3 FHAD1 SEMA6D ZNF83	4.25e-03	114	169	4	EFO_0803327
Disease	Drug habituation	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C0013170
Disease	Drug abuse	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C0013146
Disease	Prescription Drug Abuse	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C4316881
Disease	Substance-Related Disorders	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C0236969
Disease	Drug Use Disorders	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C0013222
Disease	Drug Dependence	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C1510472
Disease	Substance Dependence	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C0038580
Disease	Substance Use Disorders	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	FAM184B CDCP1 SEMA6D CSMD1	4.38e-03	115	169	4	C0029231
Disease	Substance abuse problem	FAM184B CDCP1 SEMA6D CSMD1	4.52e-03	116	169	4	C0740858
Disease	corneal resistance factor	TCF7L2 HAGHL ZNF407 SLC6A15 MAMDC2 TET1 GALNT6 HERC2	4.62e-03	451	169	8	EFO_0010067
Disease	cortical surface area measurement	ROCK2 EFCAB5 SHROOM3 TCF7L2 NSF CHAF1A DOCK10 SLC6A15 CPED1 NRP1 SLIT2 FAM13A PKHD1 MPHOSPH9 FGD6 PLXNA2	4.66e-03	1345	169	16	EFO_0010736
Disease	Feeding difficulties	CDK8 ZNF292	4.70e-03	18	169	2	C0232466
Disease	response to bronchodilator, FEV/FEC ratio	TCF7L2 GRID2 GCNT1 BTBD9 SERPINA2 MGAT5 SEMA6D FAM13A PKHD1 LRRC7 PLXNA2	4.80e-03	766	169	11	EFO_0004713, GO_0097366
Disease	Colorectal Neoplasms	TCF7L2 ABCA13 LAMA1 GNB5 CTBP1 ZNF292	5.37e-03	277	169	6	C0009404
Disease	alcohol use disorder (implicated_via_orthology)	EPS8L2 CHRNB2 RYR3 CTBP1 UNC79	5.41e-03	195	169	5	DOID:1574 (implicated_via_orthology)
Disease	chronic obstructive pulmonary disease (is_implicated_in)	IL13RA1 CLCA1 FAM13A	5.70e-03	63	169	3	DOID:3083 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LQDPEHFTNFEKCLS	EPG5	751	Q9HCE0
DCVQELSHSVNKLFG	COG7	386	P83436
QALEECSKFPENQHK	ARHGEF6	301	Q15052
EPIFHCRQEDIKTSN	CDK19	231	Q9BWU1
PVDCEAQKEHTFTIQ	CLSTN3	96	Q9BQT9
CHEGFKLESSQQATA	CSMD1	2521	Q96PZ7
VAFCDAQSTQEIHEK	CTBP1	51	Q13363
HEVSCPQASFDKENA	RBBP8	456	Q99708
FQSINHNEIGEKCSD	CRYBG3	886	Q68DQ2
DDENTPCHIKQIFTH	CPED1	566	A4D0V7
SGNVKLSCQFAEIHE	ALPK2	1801	Q86TB3
IGHFDSVPNIQDDCN	AFTPH	536	Q6ULP2
SCQSPENHFVIEIQK	CDCP1	81	Q9H5V8
SNENHTSCIAKEIEF	CASR	591	P41180
KDAVAFTCEPEAQNT	CEACAM5	516	P06731
NQDITDVCFSPEKDH	FBXW10	171	Q5XX13
HFNKVGCNPNEDVAI	ARFGEF2	1141	Q9Y6D5
KTVFEALQAPACHEN	AP2A1	481	O95782
ENDVFSSDCKHQLVS	ABCA13	606	Q86UQ4
HTDKVVAVQFCNNGD	BRWD3	361	Q6RI45
QALAFHFCKAQDSDT	ANKRD50	106	Q9ULJ7
SHCKSEGQEESFVPQ	DCAF6	511	Q58WW2
ENNCHVGSDIDFRPK	CHAF1A	76	Q13111
AENDNYCKHSTIVPE	DICER1	1116	Q9UPY3
SCPHNNVTGIAFEDV	CEMIP	916	Q8WUJ3
EETHICSEFFNSQAK	DISP1	1211	Q96F81
AFCSVHEKNQAGDTA	ANKRD6	196	Q9Y2G4
TQTAKNCTDPAIHEF	SLC24A4	71	Q8NFF2
ICYNEFDENVHKPIS	RC3H2	16	Q9HBD1
HRKACPFDQTAINTD	RC3H2	46	Q9HBD1
HRKACPFDQTTINTD	RC3H1	46	Q5TC82
LNQAPSSHKCAESEQ	NSD1	2681	Q96L73
SSQSPSQVDQFCKEH	RAB32	151	Q13637
QNKFPEDHTAESICE	RECK	446	O95980
GQCVQAFETHESDIN	GNB5	271	O14775
FAQKVEPCNDHVRAK	HAGHL	181	Q6PII5
VDHCPATQDNLNKDS	PCDHGB7	771	Q9Y5F8
ALDDISFSPVHCQNQ	MAMDC2	316	Q7Z304
SQHFQPDEDFSNCAK	RBL2	471	Q08999
NFDEVISCFANVPKD	ACACB	1381	O00763
NQDITDVCFSPEKDH	FBXW10B	171	O95170
PNLSDNTCHFEDEKI	MDGA1	746	Q8NFP4
KNEHFAIPAVCDSVQ	RELCH	391	Q9P260
CYIPNHSNSKNVDVE	MAP1B	2361	P46821
PKEAFHSNFVSLDCD	LDB1	146	Q86U70
CITHQEGEKISANEN	LIMA1	316	Q9UHB6
VDSPHCKTFVDNIQT	INTS1	241	Q8N201
INAFIEKQDFCHGQV	MGAT5	616	Q09328
HCSLQQVPKEVFNFE	LRRC7	31	Q96NW7
VDGANCQHVFVLKTF	GTSF1L	106	Q9H1H1
NDQCQHFDTLRVTKP	HERC2	736	O95714
CTKQLAAAFHEEFVV	FXR1	211	P51114
SQVQEKNFDHPIFCC	CFAP65	1341	Q6ZU64
ELSEQQAACSGHQKD	FAM184B	736	Q9ULE4
VNSLCTDDDSPHKQF	GRID2	881	O43424
QVANSAFVECLQKHG	HSP90AA5P	186	Q58FG0
EEFHCKLQEATNFPL	CBFA2T2	156	O43439
QFVFDIHKGSITDAC	PLXNA2	1756	O75051
HTEVQFQKECGPDNK	ITGA3	606	P26006
AAFEFDIHQVIKECS	NUP85	351	Q9BW27
ADTFVEHKIISFNGC	OR4S1	81	Q8NGB4
EKEVGNCSPHFLNAF	NFE2L2	236	Q16236
SHGEIFKKDVCAENN	EVI2A	116	P22794
NQDCGDHKSEIIQSF	EVI2B	381	P34910
AECTVFLDHENANKI	F9	26	P00740
GNPCHEASAAQKENA	DCD	31	P81605
VKNENFYIQTPEECH	MPHOSPH9	91	Q99550
FSPADEAFVCQKKNH	MYRFL	251	Q96LU7
SCQQAFEHFAQKGPT	KDM4B	546	O94953
TECHARFKTPEDAQA	LARP7	491	Q4G0J3
CAVVNEKDFQSGQHV	NSF	21	P46459
SGKQSIAIDDCTFHQ	AP2M1	236	Q96CW1
SVKNNFEFCEAHIPF	AP5M1	346	Q9H0R1
SHVASECNNEQFPLE	OTUD7A	131	Q8TE49
ACEELSAAFQKHLQE	MROH1	1526	Q8NDA8
QEASHRQFCESKNGP	ARHGAP32	1881	A7KAX9
EELAQCTSHPQVKEA	RALGAPA2	1171	Q2PPJ7
TQEVEKVHKNTFGCA	FAM13A	446	O94988
TTANEDLEKQGCHPF	NBAS	1461	A2RRP1
QDSEQSKPDVHFFHC	EPS8L2	141	Q9H6S3
NNCVFAPADVTSEKD	HSD17B10	56	Q99714
EENILNCFDKAVHGS	PRPF39	546	Q86UA1
THNVFYVQEAKCENP	IL13RA1	271	P78552
NDPSFANEIIKACHQ	ETAA1	581	Q9NY74
QAFQFTDKHGEVCPA	PRDX1	161	Q06830
FNVTPQDEQKFHCLV	ICOSLG	101	O75144
NNHISQEDCAKPADL	NRP1	801	O14786
DTITPQQVFVKCHFD	PALS2	211	Q9NZW5
NNICAFDPTAKHVEV	EFCAB5	1416	A4FU69
TETPEAKIHECFQQV	SERPINA2	111	P20848
GTFVNECHIQNVAVK	FHAD1	61	B1AJZ9
CQEPAQRHFFSKHDN	C3orf84	46	H3BNL1
QDPHVNAFFQECQKR	DOCK10	856	Q96BY6
KAFQDADVTCVFHIA	SDR42E1	66	Q8WUS8
SNVEKHFGELCQIFA	CIBAR1	21	A1XBS5
HKDTAQAPEIFQRCD	DKK4	181	Q9UBT3
PQEDLHAVVKNCFAV	GLT1D1	231	Q96MS3
SPQETQKFCEQVHAA	CCNDBP1	81	O95273
EDVNDNPATCQKFTF	CDHR3	336	Q6ZTQ4
CHFTGKNSQVPKDEE	GALNT6	566	Q8NCL4
NGCTEFKSPNNHFVV	CCDC73	526	Q6ZRK6
HVNFKTEGSRFQDCV	GIMAP8	201	Q8ND71
LAFSCDVAKEHDVQN	CBR4	51	Q8N4T8
PKQCDSSNISHVENE	CCP110	171	O43303
SHTDKVDSIQFCNNG	BRWD1	366	Q9NSI6
KCFSEKDQTQGHDQS	DUXB	76	A0A1W2PPF3
FSQNCIKPVEEIVHS	ATF7IP2	91	Q5U623
LNENIKHFCTNPDSV	HEPHL1	241	Q6MZM0
ITQHISCAFGLKNEE	FIGLA	156	Q6QHK4
PQNFYCIHVDTKSED	GCNT1	146	Q02742
LKCTVFHGAQVEDAF	FASN	1826	P49327
CVHFECPEQQSSQKE	BTBD9	551	Q96Q07
EPIFHCRQEDIKTSN	CDK8	231	P49336
HCQDQNVPVENFFVK	SDE2	36	Q6IQ49
QHFEKFQSESCPVVG	KIF1A	916	Q12756
HLPNCSVISQDDFFK	NMRK1	26	Q9NWW6
ANAEKAESHNDCPVR	UPP1	6	Q16831
KNASHTFVEPECEQS	SLC6A15	186	Q9H2J7
ENACATKEQKNHTFP	PLD5	421	Q8N7P1
HCQEQKLEPVNAASF	RFX1	466	P22670
HCQEHKLDPVNAASF	RFX3	211	P48380
NFSPTCHLNDGDEVV	LAMA1	801	P25391
EQANCSFQVFDKHPG	SETX	141	Q7Z333
KVHFCSVPENEEDAS	SHROOM3	556	Q8TF72
AALAHQGCDINFKEV	SBNO2	1301	Q9Y2G9
SFDCIQDKVKPHSAN	PKHD1	3211	P08F94
DEDFFQKNACHSNVT	STARD9	1646	Q9P2P6
KQDHVQCPEASTGFE	STARD9	2831	Q9P2P6
KQGSATDNVCHLFAE	TNS3	1406	Q68CZ2
AFHSNAEKILQDCPE	SESTD1	606	Q86VW0
AKPDHQEAFEATANQ	TET1	341	Q8NFU7
KIEVKHFPFDQQNCT	CHRNB2	156	P17787
IVEFCTEQNHNKEAP	CLCA1	246	A8K7I4
QSIDSVVEFCNEKTH	CLCA4	241	Q14CN2
VVEFCNEKTHNQEAP	CLCA4	246	Q14CN2
FSSDPLQKVVCFNHD	PREB	151	Q9HCU5
CEHTKSLSPFNDVVD	RNF213	4111	Q63HN8
CNQRFPSEDAVEKHV	ZNF451	476	Q9Y4E5
DCGKAFTQSANLIVH	ZNF35	366	P13682
ELVNAACNFEPHESF	ZER1	56	Q7Z7L7
SNQIKEFSPGCFHAI	TLR3	206	O15455
KSQTEPQENVCHLFA	TNS4	676	Q8IZW8
CFVVTGEDHQKQSPE	RYR3	1671	Q15413
KVPHQEENGCADFFI	SPRED1	46	Q7Z699
NKSLHPQENDCFIGD	UBE3D	151	Q7Z6J8
EECGKAFNQPSHLAT	ZNF723	316	P0DPD5
RDKQPGETNEHSECF	TCF7L2	431	Q9NQB0
GHKQELAESTDNFNC	FGD6	81	Q6ZV73
IKHPSVNENFCNEKE	PLAA	621	Q9Y263
CNEKEGAQFSSHLIN	PLAA	631	Q9Y263
HVCPCKESETFVQFA	ZNF292	2641	O60281
NSLCFPEDAEISKHA	ROCK2	311	O75116
NVAEVQKREFVCSGH	SLIT2	246	O94813
FPGCSKQAHQEDLSD	TSPAN12	186	O95859
NESFCHQISENIGSK	SLF1	516	Q9BQI6
RTEQQFHPESTKCND	UNKL	276	Q9H9P5
TDFHKQVTSAEECKQ	TNPO3	896	Q9Y5L0
HCNEFGEAFIQSSKL	ZNF841	566	Q6ZN19
KSHFQLDPESQCSFG	ZNF786	111	Q8N393
EKNNECHEPEKSFSL	ZNF655	126	Q8N720
QHDPNITDKSECFLQ	TRIM51G	316	A0A3B3IT33
VICSHFAQDFSPEQN	ZNF681	76	Q96N22
DTCGKDFSQISHLQA	ZNF233	511	A6NK53
FKADVSVPHTGENCS	STMND1	26	H3BQB6
HSNQEDTGCKFQVLP	PMS2CL	166	Q68D20
EAQVTLECAIPQKFH	HDLBP	871	Q00341
CEAQFSSETALKQHA	ZNF142	1291	P52746
DHSFCETFQQAPVKD	ZNF407	1161	Q9C0G0
SKVFDEVFPLAHVCN	VWA3B	886	Q502W6
HPEEFCEFVKSNTEQ	ZBED1	71	O96006
DSSVKFCKNEPQDHQ	ZNF239	76	Q16600
DECHNFIKVFVPRND	SEMA6D	116	Q8NFY4
FQLHDCTQVEKADTT	PTPRC	306	P08575
KENCRFSHGQVVSLD	ZGPAT	191	Q8N5A5
EFGKVFNQCSHLTEH	ZNF195	331	O14628
VQHQSIHTEEKPFEC	ZNF181	421	Q2M3W8
DECDKAFSQNSHLVQ	ZNF83	376	P51522
NCTEPVEHAAVKNDT	UNC79	926	Q9P2D8
AGAQKCHSVITQDFL	TPP1	106	O14773