Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	leukemia inhibitory factor receptor activity	LIFR IL6ST	6.95e-05	2	167	2	GO:0004923
GeneOntologyMolecularFunction	phosphatidylinositol binding	FLII ADAP1 OBSCN GRB7 SYT7 ITPR3 ARAP3 PIK3C2B SVIL SYT1 AKT1	7.40e-05	316	167	11	GO:0035091
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	OBSCN ARAP3 AKT1 PLEK	2.02e-04	35	167	4	GO:0043325
GeneOntologyMolecularFunction	oncostatin-M receptor activity	LIFR IL6ST	2.07e-04	3	167	2	GO:0004924
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	FLII ADAP1 OBSCN SYT7 ARAP3 SVIL SYT1 AKT1	2.77e-04	199	167	8	GO:1901981
GeneOntologyMolecularFunction	ciliary neurotrophic factor receptor activity	LIFR IL6ST	4.13e-04	4	167	2	GO:0004897
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate binding	FLII ADAP1 OBSCN SYT7 SVIL SYT1	5.44e-04	121	167	6	GO:1902936
GeneOntologyMolecularFunction	pheromone binding	OBP2B OBP2A	6.84e-04	5	167	2	GO:0005550
GeneOntologyMolecularFunction	inositol 1,3,4,5 tetrakisphosphate binding	ADAP1 ITPR3	6.84e-04	5	167	2	GO:0043533
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	ADAP1 OBSCN ARAP3 AKT1	7.46e-04	49	167	4	GO:0005547
GeneOntologyMolecularFunction	protein-cysteine S-myristoyltransferase activity	ZDHHC7 ZDHHC17	1.02e-03	6	167	2	GO:0019705
GeneOntologyMolecularFunction	neuregulin binding	ITGA6 ITGAV	1.02e-03	6	167	2	GO:0038132
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THSD4 COL19A1 LAMA2 LAMA3 THBS1 VCAN FGG	1.05e-03	188	167	7	GO:0005201
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate binding	FLII OBSCN SYT7 SVIL SYT1	1.22e-03	95	167	5	GO:0005546
GeneOntologyMolecularFunction	ciliary neurotrophic factor receptor binding	LIFR IL6ST	1.42e-03	7	167	2	GO:0005127
GeneOntologyMolecularFunction	protein-cysteine S-stearoyltransferase activity	ZDHHC7 ZDHHC17	1.42e-03	7	167	2	GO:0140439
GeneOntologyMolecularFunction	fibroblast growth factor binding	ITGAV THBS1 KLB	1.45e-03	27	167	3	GO:0017134
GeneOntologyBiologicalProcess	positive regulation of mRNA splicing, via spliceosome	SF3B4 RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F	5.99e-08	44	167	7	GO:0048026
GeneOntologyBiologicalProcess	positive regulation of mRNA processing	SF3B4 RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F	1.30e-07	49	167	7	GO:0050685
GeneOntologyBiologicalProcess	positive regulation of RNA splicing	SF3B4 RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F	7.60e-07	63	167	7	GO:0033120
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	SF3B4 SFSWAP RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F	1.04e-05	129	167	8	GO:0048024
GeneOntologyBiologicalProcess	regulation of mRNA processing	SF3B4 SFSWAP RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F	4.49e-05	158	167	8	GO:0050684
GeneOntologyBiologicalProcess	wound healing	DGKZ ST3GAL4 ENPP4 ITGAV SYT7 JAK2 THBS1 SLC11A1 NFATC1 SYK FGG PLEK ALOX5 IL6ST	5.06e-05	493	167	14	GO:0042060
GeneOntologyBiologicalProcess	hemostasis	FLI1 DGKZ ST3GAL4 ENPP4 JAK2 THBS1 SYK FGG PLEK IL6ST	6.86e-05	268	167	10	GO:0007599
GeneOntologyBiologicalProcess	protein autophosphorylation	MAK OBSCN TRIM24 MAP3K3 STK16 JAK2 PPP2CA SYK AKT1	1.04e-04	228	167	9	GO:0046777
GeneOntologyCellularComponent	spliceosomal complex	SF3B4 RBMY1A1 RBMY1C DDX42 RBMY1D RBMY1B RBMY1E RBMY1F RBM41	5.99e-05	215	167	9	GO:0005681
GeneOntologyCellularComponent	anchoring junction	FLII CDHR2 GJB4 ASH1L OBSCN APC LAMA3 GRB7 ITGA6 LASP1 ITGAV JAK2 FZD5 SVIL NECTIN2 AKT1 KIFC3 FLRT1 FYB1 CDH9	1.07e-04	976	167	20	GO:0070161
Domain	RBM1CTR	RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F	2.86e-09	8	166	5	PF08081
Domain	RBM1CTR	RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F	2.86e-09	8	166	5	IPR012604
Domain	RRM	SF3B4 RBMY1A1 RBMY1D RBMY1B RBMY1E SCAF4 RBMY1F RBM6 RBM41	1.43e-04	217	166	9	SM00360
Domain	Laminin_G	FAT4 COL19A1 LAMA2 LAMA3 THBS1	1.64e-04	58	166	5	IPR001791
Domain	PH	ADAP1 OBSCN GRB7 SYNGAP1 ARHGEF40 ARAP3 ELMO2 AKT1 PLEK ACAP3	1.97e-04	278	166	10	SM00233
Domain	RRM_dom	SF3B4 RBMY1A1 RBMY1D RBMY1B RBMY1E SCAF4 RBMY1F RBM6 RBM41	2.01e-04	227	166	9	IPR000504
Domain	PH_DOMAIN	ADAP1 OBSCN GRB7 SYNGAP1 ARHGEF40 ARAP3 ELMO2 AKT1 PLEK ACAP3	2.02e-04	279	166	10	PS50003
Domain	PH_domain	ADAP1 OBSCN GRB7 SYNGAP1 ARHGEF40 ARAP3 ELMO2 AKT1 PLEK ACAP3	2.08e-04	280	166	10	IPR001849
Domain	RRM	SF3B4 RBMY1A1 RBMY1D RBMY1B RBMY1E SCAF4 RBMY1F RBM6 RBM41	2.21e-04	230	166	9	PS50102
Domain	von_Ebner_gland	OBP2B OBP2A	2.34e-04	3	166	2	IPR002450
Domain	LIPOCALIN	OBP2B OBP2A PTGDS	4.28e-04	17	166	3	PS00213
Domain	HoxA13_N	HOXD13 HOXB13	4.66e-04	4	166	2	PF12284
Domain	HoxA13_N	HOXD13 HOXB13	4.66e-04	4	166	2	IPR022067
Domain	Lipocalin	OBP2B OBP2A PTGDS	5.10e-04	18	166	3	IPR002345
Domain	Nucleotide-bd_a/b_plait	SF3B4 RBMY1A1 RBMY1D RBMY1B RBMY1E SCAF4 RBMY1F RBM6 RBM41	5.13e-04	258	166	9	IPR012677
Domain	RRM_1	SF3B4 RBMY1A1 RBMY1D RBMY1B RBMY1E SCAF4 RBMY1F RBM41	5.55e-04	208	166	8	PF00076
Domain	Laminin_domII	LAMA2 LAMA3	7.72e-04	5	166	2	IPR010307
Domain	Laminin_aI	LAMA2 LAMA3	7.72e-04	5	166	2	IPR009254
Domain	Laminin_I	LAMA2 LAMA3	7.72e-04	5	166	2	PF06008
Domain	Laminin_II	LAMA2 LAMA3	7.72e-04	5	166	2	PF06009
Pathway	PID_INTEGRIN1_PATHWAY	LAMA2 LAMA3 ITGA6 ITGAV THBS1 FGG	2.90e-05	66	128	6	M18
Pathway	REACTOME_HEMOSTASIS	GRB7 ITGA6 DGKZ ITGAV ITPR3 JAK2 PPP2CA PPP2CB THBS1 SYK AKT1 AKAP10 FGG PLEK ATP2B4 KLC1	5.92e-05	571	128	16	MM14472
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	ADAP1 LAMA2 LAMA3 GRB7 ITGAV RIT2 ITPR3 JAK2 PPP2CA PPP2CB THBS1 ELMO2 AKT1 FLRT1 KLB	9.56e-05	532	128	15	M27870
Pathway	PID_INTEGRIN4_PATHWAY	LAMA2 LAMA3 ITGA6	1.14e-04	11	128	3	M158
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMA2 LAMA3 ITGA6 ITGAV	1.48e-04	30	128	4	M27216
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	APC PPP2CA PPP2CB FZD5	1.69e-04	31	128	4	M27400
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	APC PPP2CA PPP2CB FZD5	1.69e-04	31	128	4	MM15154
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	LAMA2 LAMA3 ITGA6 ITGAV THBS1	1.93e-04	59	128	5	M27218
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA2 LAMA3 ITGA6 AKT1	2.16e-04	33	128	4	M39503
Pathway	REACTOME_SIGNALING_BY_WNT_IN_CANCER	APC PPP2CA PPP2CB FZD5	2.44e-04	34	128	4	M27405
Pubmed	A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.	RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F	8.39e-14	7	169	6	8269511
Pubmed	Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.	RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E RBMY1F	1.09e-11	12	169	6	9598316
Pubmed	RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.	RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F	1.53e-11	6	169	5	15184870
Pubmed	Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.	RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F	5.32e-11	7	169	5	8875892
Pubmed	An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells.	RBMY1A1 RBMY1D RBMY1B RBMY1E	2.68e-09	5	169	4	8817321
Pubmed	Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.	RBMY1A1 RBMY1D RBMY1B RBMY1E	2.68e-09	5	169	4	20016065
Pubmed	The role of human and mouse Y chromosome genes in male infertility.	RBMY1A1 RBMY1D RBMY1B RBMY1E	2.68e-09	5	169	4	11097427
Pubmed	Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.	RBMY1A1 RBMY1D RBMY1B RBMY1E	2.68e-09	5	169	4	19737860
Pubmed	Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.	RBMY1A1 RBMY1D RBMY1B RBMY1E	8.01e-09	6	169	4	12356914
Pubmed	Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.	RBMY1A1 RBMY1D RBMY1B RBMY1E	8.01e-09	6	169	4	9499427
Pubmed	Does Rbmy have a role in sperm development in mice?	RBMY1A1 RBMY1D RBMY1B RBMY1E	8.01e-09	6	169	4	15051956
Pubmed	Identification of target messenger RNA substrates for mouse RBMY.	RBMY1A1 RBMY1D RBMY1B RBMY1E	8.01e-09	6	169	4	18492746
Pubmed	The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.	RBMY1A1 RBMY1D RBMY1B RBMY1E	8.01e-09	6	169	4	18239052
Pubmed	The roles of RNA-binding proteins in spermatogenesis and male infertility.	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.86e-08	7	169	4	10377282
Pubmed	RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.86e-08	7	169	4	17001072
Pubmed	Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.	RBMY1A1 RBMY1D RBMY1B RBMY1E	3.71e-08	8	169	4	7479793
Pubmed	Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.10e-07	10	169	4	10601091
Pubmed	Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.10e-07	10	169	4	9384609
Pubmed	Epstein-Barr virus latent membrane protein-2A induces ITAM/Syk- and Akt-dependent epithelial migration through αv-integrin membrane translocation.	ITGAV SYK AKT1	1.13e-07	3	169	3	22837212
Pubmed	The role of Dby mRNA in early development of male mouse zygotes.	RBMY1A1 RBMY1D RBMY1B RBMY1E	2.58e-07	12	169	4	20543856
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	MAK CDHR2 TMEM126B VSIG4 APC ST3GAL4 ADCY7 STK16 LIFR ATXN1 TMEM106C VCAN RECQL5 RCOR3 AKAP10 TOMM40 CSNK1G2-AS1 GAPDHS FYB1 ANO3 GOLGB1 KLC1	3.54e-07	1293	169	22	15342556
Pubmed	GASZ promotes germ cell derivation from embryonic stem cells.	RBMY1A1 RBMY1D RBMY1B RBMY1E	3.72e-07	13	169	4	23816659
Pubmed	RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.	RBMY1A1 RBMY1C RBMY1B RBMY1F	3.72e-07	13	169	4	10749975
Pubmed	PML regulates apoptosis at endoplasmic reticulum by modulating calcium release.	ITPR3 PPP2CA AKT1	4.49e-07	4	169	3	21030605
Pubmed	A possible implication of reduced levels of LIF, LIFR, and gp130 in vasculopathy related to systemic sclerosis.	FLI1 LIFR IL6ST	4.49e-07	4	169	3	29038846
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII OBSCN ZDHHC7 ADCY7 ITPR3 JAK2 ZGPAT PPP2CB ARHGEF40 ARAP3 PNPLA6 NFATC1 PIK3C2B DIP2C LRP4 AKT1 KIFC3 SSBP4 ALOX5 HOXB13	4.86e-07	1105	169	20	35748872
Pubmed	Absence of mDazl produces a final block on germ cell development at meiosis.	RBMY1A1 RBMY1D RBMY1B RBMY1E	5.19e-07	14	169	4	14611631
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	RBMY1A1 RBMY1D RBMY1B RBMY1E	7.04e-07	15	169	4	14762062
Pubmed	Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.	APC FZD5 IL6ST	1.12e-06	5	169	3	30622113
Pubmed	Loss of maternal Trim28 causes male-predominant early embryonic lethality.	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.22e-06	17	169	4	28115466
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CYLD FBXW12 DDX42 ASH1L OBSCN APC DGKZ PYM1 ZDHHC17 ME2 MAP3K3 ALDH1L2 TMEM106C SIPA1L1 VCAN SYT1 RCOR3 ATP11A GOLGB1	1.54e-06	1084	169	19	11544199
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.56e-06	18	169	4	12023983
Pubmed	SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.	NECTIN2 TOMM40 SORL1	3.89e-06	7	169	3	23565137
Pubmed	Physical proximity and functional cooperation of glycoprotein 130 and glycoprotein VI in platelet membrane lipid rafts.	JAK2 SYK IL6ST	3.89e-06	7	169	3	31145836
Pubmed	GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin.	APC PPP2CA PPP2CB	3.89e-06	7	169	3	10698523
Pubmed	Akt and PP2A reciprocally regulate the guanine nucleotide exchange factor Dock6 to control axon growth of sensory neurons.	PPP2CA PPP2CB AKT1	6.20e-06	8	169	3	23462102
Pubmed	Human transcription factor protein interaction networks.	CYLD FLI1 SIN3B RTCB STRBP MSANTD2 LASP1 TRIM24 SCAF4 PPP2CA SALL2 NKX2-4 ATXN1 GLO1 MORF4L1 RECQL5 SVIL RBM6 RCOR3 SSBP4 SORL1	6.60e-06	1429	169	21	35140242
Pubmed	Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.	PYM1 MAP3K3 STK16 SYK SYT1 AKT1 KIFC3 SLC23A2	7.33e-06	203	169	8	19953087
Pubmed	MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.	RBMY1A1 RBMY1D RBMY1B RBMY1E	7.40e-06	26	169	4	35920200
Pubmed	Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes.	TBX15 ALX1 PAX1	9.27e-06	9	169	3	15728667
Pubmed	Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.	FLII DDX42 THBS1 SVIL RBM6 LRP4 SORL1	1.20e-05	156	169	7	29961565
Pubmed	Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse.	LAMA2 ITGA6 ITGAV	1.81e-05	11	169	3	15739233
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CYLD FLII SIN3B APC MSANTD2 DGKZ ARHGAP39 SYNGAP1 PPP2CB SIPA1L1 MORF4L1 SVIL SYT1 ATP2B4 GOLGB1 KLC1	2.07e-05	963	169	16	28671696
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CYLD SF3B4 RTCB APC MAP3K3 VPS13D ATXN1 PIK3C2B ELMO2 AASS SIPA1L1 SVIL NECTIN2 GOLGB1 KLC1	2.20e-05	861	169	15	36931259
Pubmed	Anodized-hydrothermally treated titanium with a nanotopographic surface structure regulates integrin-α6β4 and laminin-5 gene expression in adherent murine gingival epithelial cells.	LAMA3 ITGA6	2.35e-05	2	169	2	23415882
Pubmed	TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures.	PTGDS ANO3	2.35e-05	2	169	2	33972431
Pubmed	CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.	NFATC1 SYK	2.35e-05	2	169	2	31921172
Pubmed	IL-32 aggravates metabolic disturbance in human nucleus pulposus cells by activating FAT4-mediated Hippo/YAP signaling.	FAT4 IL32	2.35e-05	2	169	2	39178518
Pubmed	Sesquiterpene dimmer (DSF-27) inhibits the release of neuroinflammatory mediators from microglia by targeting spleen tyrosine kinase (Syk) and Janus kinase 2 (Jak2): Two major non-receptor tyrosine signaling proteins involved in inflammatory events.	JAK2 SYK	2.35e-05	2	169	2	24486434
Pubmed	Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop.	ASH1L MORF4L1	2.35e-05	2	169	2	30827841
Pubmed	Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.	ASH1L MORF4L1	2.35e-05	2	169	2	30827843
Pubmed	Ultraviolet radiation attenuates thrombospondin 1 expression via PI3K-Akt activation in human keratinocytes.	THBS1 AKT1	2.35e-05	2	169	2	16478297
Pubmed	Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.	PPP2CA PPP2CB	2.35e-05	2	169	2	11751260
Pubmed	Membrane-Binding Cooperativity and Coinsertion by C2AB Tandem Domains of Synaptotagmins 1 and 7.	SYT7 SYT1	2.35e-05	2	169	2	30795874
Pubmed	Effect of Recql5 deficiency on the intestinal tumor susceptibility of Apc(min) mice.	APC RECQL5	2.35e-05	2	169	2	20333788
Pubmed	Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.	ATXN1 AKT1	2.35e-05	2	169	2	12741986
Pubmed	Association and interaction of TOMM40 and PVRL2 with plasma amyloid-β and Alzheimer's disease among Chinese older adults: a population-based study.	NECTIN2 TOMM40	2.35e-05	2	169	2	35093267
Pubmed	Early changes of LIFR and gp130 in sciatic nerve and muscle of diabetic mice.	LIFR IL6ST	2.35e-05	2	169	2	21565387
Pubmed	Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization.	APC NFATC1	2.35e-05	2	169	2	28978472
Pubmed	Thrombospondin 1--a regulator of adenoma growth and carcinoma progression in the APC(Min/+) mouse model.	APC THBS1	2.35e-05	2	169	2	12584168
Pubmed	Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway.	APC ALOX5	2.35e-05	2	169	2	29339153
Pubmed	Upregulation of thrombospondin-1 expression by leptin in vascular smooth muscle cells via JAK2- and MAPK-dependent pathways.	JAK2 THBS1	2.35e-05	2	169	2	22592401
Pubmed	Macromolecular organization of basement membranes.	LAMA2 LAMA3	2.35e-05	2	169	2	8939648
Pubmed	Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.	LIFR IL6ST	2.35e-05	2	169	2	1915266
Pubmed	Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties.	OBP2B OBP2A	2.35e-05	2	169	2	12044155
Pubmed	A comprehensive clinical study of integrins in acute lymphoblastic leukemia indicates a role of α6/CD49f in persistent minimal residual disease and α5 in the colonization of cerebrospinal fluid.	ITGA6 ITGAV	2.35e-05	2	169	2	32107949
Pubmed	The role of protein phosphatase 2A catalytic subunit Calpha in embryogenesis: evidence from sequence analysis and localization studies.	PPP2CA PPP2CB	2.35e-05	2	169	2	10543450
Pubmed	Selective modulation of subtype III IP₃R by Akt regulates ER Ca²⁺ release and apoptosis.	ITPR3 AKT1	2.35e-05	2	169	2	22552281
Pubmed	Genetic deletion of 5-lipoxygenase increases tumor-infiltrating macrophages in Apc(Δ468) mice.	APC ALOX5	2.35e-05	2	169	2	22072302
Pubmed	Over expression of proteins that alter the intracellular signaling pathways in the cytoplasm of the liver cells forming Mallory-Denk bodies.	SYK AKT1	2.35e-05	2	169	2	28089901
Pubmed	Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes.	PPP2CA PPP2CB	2.35e-05	2	169	2	1846293
Pubmed	PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.	PPP2CA PPP2CB	2.35e-05	2	169	2	27096707
Pubmed	Synaptotagmins 1 and 7 in vesicle release from rods of mouse retina.	SYT7 SYT1	2.35e-05	2	169	2	36280223
Pubmed	The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGFβ-induced pulmonary fibrosis.	THBS1 AKT1	2.35e-05	2	169	2	26033700
Pubmed	Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A.	PPP2CA PPP2CB	2.35e-05	2	169	2	2555176
Pubmed	The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.	SYT7 SYT1	2.35e-05	2	169	2	28813412
Pubmed	A switch toward angiostatic gene expression impairs the angiogenic properties of endothelial progenitor cells in low birth weight preterm infants.	THBS1 AKT1	2.35e-05	2	169	2	21659549
Pubmed	Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.	PPP2CA AKT1	2.35e-05	2	169	2	11839802
Pubmed	Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells.	SYT7 SYT1	2.35e-05	2	169	2	18308932
Pubmed	D-AKAP2:PKA RII:PDZK1 ternary complex structure: insights from the nucleation of a polyvalent scaffold.	PDZK1 AKAP10	2.35e-05	2	169	2	25348485
Pubmed	Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.	SYT7 SYT1	2.35e-05	2	169	2	20824061
Pubmed	Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed in Atomic Detail.	SYT7 SYT1	2.35e-05	2	169	2	27997124
Pubmed	PDZK1: II. an anchoring site for the PKA-binding protein D-AKAP2 in renal proximal tubular cells.	PDZK1 AKAP10	2.35e-05	2	169	2	14531807
Pubmed	Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.	THBS1 AKT1	2.35e-05	2	169	2	16227992
Pubmed	Determinants for the interaction between Janus kinase 2 and protein phosphatase 2A.	JAK2 PPP2CA	2.35e-05	2	169	2	12921784
Pubmed	Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice.	APC ALOX5	2.35e-05	2	169	2	21216893
Pubmed	A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres.	OBP2B OBP2A	2.35e-05	2	169	2	10607840
Pubmed	Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies.	JAK2 PPP2CA	2.35e-05	2	169	2	23926298
Pubmed	Synaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter release.	SYT7 SYT1	2.35e-05	2	169	2	24267651
Pubmed	Hoxb13 is required for normal differentiation and secretory function of the ventral prostate.	HOXD13 HOXB13	2.35e-05	2	169	2	12668621
Pubmed	A molecular pathogenesis for transcription factor associated poly-alanine tract expansions.	HOXD13 HOXB13	2.35e-05	2	169	2	15333588
Pubmed	MRG15 activates histone methyltransferase activity of ASH1L by recruiting it to the nucleosomes.	ASH1L MORF4L1	2.35e-05	2	169	2	37527654
Pubmed	Phosphorylation of ATXN1 at Ser776 in the cerebellum.	ATXN1 AKT1	2.35e-05	2	169	2	19500214
Pubmed	Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.	PDZK1 AKT1	2.35e-05	2	169	2	38669103
Pubmed	Cycles of ubiquitination and deubiquitination critically regulate growth factor-mediated activation of Akt signaling.	CYLD AKT1	2.35e-05	2	169	2	23300340
Pubmed	Regional expression of protein phosphatase type 1 and 2A catalytic subunit isoforms in the human heart.	PPP2CA PPP2CB	2.35e-05	2	169	2	11113010
Pubmed	Synaptotagmins 1 and 7 Play Complementary Roles in Somatodendritic Dopamine Release.	SYT7 SYT1	2.35e-05	2	169	2	35361702
Pubmed	Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis.	RBMY1A1 RBMY1B	2.35e-05	2	169	2	32473614
Pubmed	Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7.	SYT7 SYT1	2.35e-05	2	169	2	22966849
Pubmed	Epigenetic silencing of novel tumor suppressors in malignant melanoma.	SYK HOXB13	2.35e-05	2	169	2	17145863
Cytoband	Yq11.223	RBMY1A1 RBMY1D RBMY1B RBMY1E RBMY1F	2.55e-05	93	169	5	Yq11.223
Cytoband	15q24	CHRNA3 MORF4L1 ARNT2	6.21e-05	21	169	3	15q24
GeneFamily	RNA binding motif containing	SF3B4 RBMY1A1 RBMY1C RBMY1D RBMY1B RBMY1E SCAF4 RBMY1F RBM6 RBM41	3.25e-06	213	130	10	725
GeneFamily	Lipocalins	OBP2B OBP2A PTGDS	3.24e-04	19	130	3	631
GeneFamily	Gelsolin/villins	FLII SVIL	1.40e-03	8	130	2	950
GeneFamily	ArfGAPs	ADAP1 ARAP3 ACAP3	1.69e-03	33	130	3	395
GeneFamily	Doublecortin superfamily	DCDC1 RP1	2.22e-03	10	130	2	1369
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	SIN3B MORF4L1	3.23e-03	12	130	2	1243
GeneFamily	Laminin subunits	LAMA2 LAMA3	3.23e-03	12	130	2	626
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ADAP1 GRB7 ARAP3 AKT1 PLEK ACAP3	3.77e-03	206	130	6	682
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP2CA PPP2CB	3.80e-03	13	130	2	693
Coexpression	PATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_93YO_VZV_CHALLENGE_6HR_UP	QTRT2 LIFR THBS1 FZD5 SIPA1L1 VCAN UGDH ATP11A PLEK UBE2W IL6ST	3.02e-06	291	168	11	M41002
Coexpression	GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP	CYLD DDX42 ITGAV ADCY7 JAK2 FYB1 ATP2B4 IL6ST	9.41e-06	160	168	8	M339
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	THSD4 FLII VSIG4 LAMA3 ITGA6 ZDHHC7 LASP1 ITGAV THBS1 ARHGEF40 FZD5 GLO1 SIPA1L1 SVIL NECTIN2 SYK ATP11A FYB1 ATP2B4 ALOX5 IL6ST VAT1	2.36e-05	1276	168	22	M39173
Coexpression	LIU_SOX4_TARGETS_UP	LASP1 ENPP4 THBS1 MORF4L1 KIFC3 ATP2B4 SORL1	3.29e-05	139	168	7	M17450
Coexpression	ZHONG_PFC_C3_ASTROCYTE	SIN3B ADAP1 STRBP OBSCN ARHGAP39 PNPLA6 RECQL5 DIP2C SYT1 RSPH9 ACAP3	4.51e-05	389	168	11	M39102
Coexpression	GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_DN	DDX42 DGKZ ADCY7 MAP3K3 SVIL SYT1 RCOR3 VAT1	4.52e-05	199	168	8	M7374
Coexpression	GSE360_DC_VS_MAC_T_GONDII_DN	VSIG4 ITGA6 ZDHHC17 PTGDS SLC11A1 VCAN ALOX5 SORL1	4.52e-05	199	168	8	M5184
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_UP	FLII PRSS12 APC NFATC1 MORF4L1 LRP4 RP1 SORL1	4.68e-05	200	168	8	M5973
Coexpression	GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN	FLI1 ST3GAL4 MAP3K3 STK16 ATP11A SSBP4 UBE2W IL6ST	4.68e-05	200	168	8	M9688
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP	ZDHHC7 ST3GAL4 KATNAL1 ITPR3 PNPLA6 ATXN1 AKT1 ATP2B4	4.68e-05	200	168	8	M6524
Coexpression	GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	MGAM MAP3K3 JAK2 THBS1 ASMTL SYK AKT1 ALOX5	4.68e-05	200	168	8	M5416
Coexpression	NAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_DN	CYLD VSIG4 ENPP4 ZDHHC17 ZGPAT THBS1 NFATC1 RECQL5 PLEK	4.86e-05	260	168	9	M41075
Coexpression	CHEN_ETV5_TARGETS_TESTIS	RBMY1A1 RBMY1D RBMY1B RBMY1E	5.76e-05	33	168	4	MM701
Coexpression	BHAT_ESR1_TARGETS_VIA_AKT1_UP	SIN3B ADAP1 PDZK1 NT5DC3 ARAP3 RUVBL1 SVIL TOMM40 KLC1	8.81e-05	281	168	9	M2234
Coexpression	THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN	FLI1 FLII LASP1 ME2 MAP3K3 AKT1 SLC23A2 KLC1	1.13e-04	227	168	8	M11234
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR	OBP2A FBXW12 PRSS12 RBMY1A1 RBMY1D RBMY1B RBMY1E ITGA6 PTGDS PNPLA6 TMEM106C DIP2C HEPHL1	1.39e-04	600	168	13	MM1025
Coexpression	ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN	THSD4 OBP2A CDHR2 RBMY1A1 DDX42 OBSCN RBMY1D RBMY1B RBMY1E OR8K3 POLR3A ARAP3 HOXD13 RBMY1F GAPDHS FYB1	1.65e-04	873	168	16	M16009
Coexpression	GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP	CDHR2 PRSS12 STAC2 BEND6 ALDH1L2 CMTM5 ANO3	1.73e-04	181	168	7	M6814
Coexpression	ZHENG_IL22_SIGNALING_DN	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.98e-04	45	168	4	MM763
Coexpression	GRESHOCK_CANCER_COPY_NUMBER_UP	CYLD FLI1 APC LASP1 TRIM24 JAK2 LIFR HOXD13 SYK	2.50e-04	323	168	9	M9150
Coexpression	MIKKELSEN_ES_ICP_WITH_H3K4ME3	GJB4 PYROXD2 LAMA2 GRB7 SCML4 LIFR NSUN6 SLC11A1 AASS RECQL5 SYT1 FLRT1 FAIM2 RBM41	2.63e-04	728	168	14	M2004
Coexpression	GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN	MGAM ZDHHC17 ADCY7 SCAF4 THBS1 PLEK SORL1	2.64e-04	194	168	7	M7306
Coexpression	BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP	ITGAV THBS1 VCAN	2.72e-04	20	168	3	M45002
Coexpression	BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP	ITGAV THBS1 VCAN	2.72e-04	20	168	3	MM1336
Coexpression	GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_UP	FLII COL19A1 LASP1 TGM3 SLC23A2 ALOX5 VAT1	2.81e-04	196	168	7	M7616
Coexpression	GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP	FBXW12 TRIM24 SLC11A1 SLC12A9 TMEM106C ARNT2 TOMM40	2.90e-04	197	168	7	M8983
Coexpression	GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP	PDZK1 LAMA3 GRB7 LASP1 MAP3K3 ITPR3 VAT1	2.99e-04	198	168	7	M8370
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP	FLI1 ITPR3 VPS13D NFATC1 RCOR3 FAIM2 VAT1	3.09e-04	199	168	7	M4526
Coexpression	GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP	ADAP1 ZDHHC7 SCML4 VPS13D ELMO2 KIFC3 SORL1	3.09e-04	199	168	7	M313
Coexpression	GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN	CYLD ITGA6 DGKZ PPP2CA FYB1 IL6ST SORL1	3.09e-04	199	168	7	M8313
Coexpression	GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP	NRN1 ATP10D MAP3K3 AP3B2 SYT1 KIFC3 SORL1	3.09e-04	199	168	7	M7414
Coexpression	GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP	CYLD IL32 ITGA6 SVIL FYB1 ATP2B4 IL6ST	3.09e-04	199	168	7	M3084
Coexpression	HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN	MGAM FAT4 COL19A1 CDHR2 VSIG4 ZDHHC7 CACHD1 ARAP3 SLC11A1 VCAN SYK ALOX5 VAT1 SORL1	3.10e-04	740	168	14	M41202
Coexpression	SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1A	PYROXD2 LAMA2 LAMA3	3.16e-04	21	168	3	M1501
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN	PRSS12 APC GRB7 ITGA6 LASP1 SCML4 VAT1	3.18e-04	200	168	7	M5980
Coexpression	GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP	MGAM APC TRIM24 FAM241A LIFR RCOR3 SLC23A2	3.18e-04	200	168	7	M7294
Coexpression	GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN	SIN3B ADAP1 FAM241A JAK2 NECTIN2 SYK IL6ST	3.18e-04	200	168	7	M8635
Coexpression	GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_UP	STRBP DGKZ ADCY7 PNPLA6 RUVBL1 ELMO2 SVIL	3.18e-04	200	168	7	M3780
Coexpression	GSE29618_MONOCYTE_VS_MDC_UP	ZDHHC7 ARHGEF40 SLC11A1 ATXN1 VCAN FYB1 SORL1	3.18e-04	200	168	7	M4948
Coexpression	GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP	ZDHHC7 ARAP3 SLC11A1 ATXN1 SIPA1L1 VCAN SORL1	3.18e-04	200	168	7	M4966
Coexpression	GSE21380_NON_TFH_VS_TFH_CD4_TCELL_DN	CYLD FLII ATP10D TMEM106C MORF4L1 MED12L PLEK	3.18e-04	200	168	7	M7502
Coexpression	GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_UP	ST3GAL4 FAM241A MAP3K3 LIFR ELMO2 SVIL ANAPC16	3.18e-04	200	168	7	M6437
Coexpression	GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP	LAMA2 DGKZ ARHGAP39 ZDHHC17 VPS13D SVIL RCOR3	3.18e-04	200	168	7	M8954
Coexpression	GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP	CYLD ADCY7 PNPLA6 RECQL5 SYK ALOX5 SORL1	3.18e-04	200	168	7	M5229
Coexpression	GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN	ST3GAL4 KATNAL1 ITGAV ATP10D THBS1 ATXN1 SLC23A2	3.18e-04	200	168	7	M6513
Coexpression	GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	MGAM ZDHHC7 MAP3K3 THBS1 ARHGEF40 PNPLA6 ASMTL	3.18e-04	200	168	7	M5418
Coexpression	GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP	SFSWAP ITGA6 ARHGAP39 TRIM24 ME2 POLR3A KLC1	3.18e-04	200	168	7	M4323
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	FLI1 VSIG4 THBS1 SLC11A1 SIPA1L1 SYK MED12L SYT1 PLEK FYB1 ALOX5	1.61e-10	191	166	11	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	FLI1 VSIG4 ADCY7 THBS1 SLC11A1 SIPA1L1 SYK PLEK FYB1 ALOX5	2.95e-09	192	166	10	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	FLI1 VSIG4 THBS1 SLC11A1 SIPA1L1 SYK SYT1 PLEK FYB1 ALOX5	3.26e-09	194	166	10	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	FLI1 VSIG4 ADCY7 THBS1 SLC11A1 SIPA1L1 SYK FYB1 ALOX5	4.83e-08	193	166	9	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	LA-08._Macrophage\|LA / Chamber and Cluster_Paper	FLI1 VSIG4 THBS1 SLC11A1 SIPA1L1 SYK PLEK FYB1 ALOX5	5.28e-08	195	166	9	5e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCell	COVID-19-Myeloid-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	FLI1 MGAM SLC11A1 SIPA1L1 VCAN SYK FYB1 ALOX5 SORL1	5.52e-08	196	166	9	04d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VSIG4 THBS1 PNPLA6 VCAN SVIL SYK ALOX5 VAT1 SORL1	5.76e-08	197	166	9	33f2fe101ae5744eea3915add37e60aa398bb97f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	VSIG4 THBS1 PNPLA6 VCAN SVIL SYK ALOX5 VAT1 SORL1	5.76e-08	197	166	9	9262785807faeb32417fad7ef202405053e453e2
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	VSIG4 THBS1 PNPLA6 VCAN SVIL SYK ALOX5 VAT1 SORL1	5.76e-08	197	166	9	d8ef5cb88dd66e112cb94217b9ad5cd70164f1d0
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VSIG4 THBS1 PNPLA6 VCAN SVIL SYK ALOX5 VAT1 SORL1	5.76e-08	197	166	9	5e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCell	Severe_COVID-19-Myeloid-TRAM2\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	VSIG4 THBS1 PNPLA6 VCAN SVIL SYK ALOX5 VAT1 SORL1	5.76e-08	197	166	9	8a126cfe1529f3d75a806aa492743314a8a43ef9
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADCY7 PNPLA6 SLC11A1 VCAN SYK PLEK FYB1 ALOX5 SORL1	6.02e-08	198	166	9	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	COVID-19-kidney-Macrophages\|kidney / Disease (COVID-19 only), tissue and cell type	FLI1 VSIG4 ADCY7 SLC11A1 VCAN SYK PLEK FYB1 ALOX5	6.02e-08	198	166	9	161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell	facs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP39 ITGAV TGM3 SLC11A1 SYK PLEK FYB1 ALOX5	1.77e-07	162	166	8	484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP39 ITGAV TGM3 SLC11A1 SYK PLEK FYB1 ALOX5	1.77e-07	162	166	8	bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCell	(1)_T_CD4_naive\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CYLD IL32 ASH1L ITGA6 SCML4 FYB1 IL6ST SORL1	5.49e-07	188	166	8	b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	THSD4 OBSCN LAMA2 JAK2 SVIL DIP2C ATP11A ATP2B4	5.95e-07	190	166	8	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	FLI1 VSIG4 ADCY7 SLC11A1 SIPA1L1 SYK FYB1 ALOX5	6.44e-07	192	166	8	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	THBS1 ARHGEF40 SLC11A1 VCAN SVIL PLEK FYB1 SORL1	7.24e-07	195	166	8	ae98215b7b7f22f1aca690920ce6092dc4a3c7db
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	THBS1 ARHGEF40 SLC11A1 VCAN SVIL PLEK FYB1 SORL1	7.24e-07	195	166	8	6fcab7aa4db958ccad0300adea9aaae52ace5bff
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SCML4 SLC11A1 PLEK FYB1 ALOX5	7.24e-07	195	166	8	7b6c69df943842b566a596e30bb50dbe80dccc83
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	FLI1 ADCY7 SLC11A1 VCAN SYK PLEK FYB1 ALOX5	7.53e-07	196	166	8	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	Adult-Immune-monocyte-D122\|Adult / Lineage, Cell type, age group and donor	FLI1 ADCY7 SLC11A1 SIPA1L1 VCAN SYK FYB1 ALOX5	7.53e-07	196	166	8	16b0acb6157534938ca83d4e909471e33a7d3c52
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SLC11A1 SYK PLEK FYB1 ALOX5	7.53e-07	196	166	8	291c59b609985167c98a40d4e2caeea2fad74941
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	MGAM ADCY7 SLC11A1 VCAN SYK FYB1 ALOX5 SORL1	7.82e-07	197	166	8	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	FLI1 ADCY7 SLC11A1 VCAN SYK PLEK FYB1 ALOX5	7.82e-07	197	166	8	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	FLI1 VSIG4 PNPLA6 SLC11A1 VCAN SYK FYB1 ALOX5	8.12e-07	198	166	8	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MAP3K3 ARHGEF40 SLC11A1 VCAN SYK ATP11A PLEK SORL1	8.12e-07	198	166	8	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SLC11A1 SYK PLEK FYB1 ALOX5	8.12e-07	198	166	8	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MGAM SLC11A1 VCAN SYK PLEK FYB1 ALOX5 SORL1	8.12e-07	198	166	8	c4a004f211f72f28aacbb512c6e075cbd049be53
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	FLI1 ADCY7 MAP3K3 SLC11A1 VCAN SYK FYB1 ALOX5	8.12e-07	198	166	8	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SLC11A1 SYK PLEK FYB1 ALOX5	8.44e-07	199	166	8	04adf46975aa4194ea40c7480f8a517def5d929c
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MGAM SLC11A1 VCAN SYK PLEK FYB1 ALOX5 SORL1	8.44e-07	199	166	8	8c2ab13b5fffbab3da37041a7000d6537fc4db09
ToppCell	(02)_MMP9/10+\|World / shred by cell type by condition	IL32 ASIC2 LAMA3 ITGA6 ITGAV THBS1 ARHGEF40 VCAN	8.44e-07	199	166	8	3f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MGAM SLC11A1 VCAN SYK PLEK FYB1 ALOX5 SORL1	8.76e-07	200	166	8	1592ca96c59eb053d0f0915afb337db9f3a40c91
ToppCell	facs-Lung-EPCAM-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM SLC11A1 SYK PLEK FYB1 ALOX5 SORL1	2.28e-06	159	166	7	baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM SLC11A1 SYK PLEK FYB1 ALOX5 SORL1	2.28e-06	159	166	7	9eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 ARHGAP39 ADCY7 TGM3 SLC11A1 PLEK FYB1	2.38e-06	160	166	7	2020b6defbaf5b5db12af37f0103ac028a8ca76e
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 ARHGAP39 ADCY7 TGM3 SLC11A1 PLEK FYB1	2.38e-06	160	166	7	af7cf0dc5fe7c02f7d6c436f6dde766c79ff0eae
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM SLC11A1 SYK PLEK FYB1 ALOX5 SORL1	2.59e-06	162	166	7	ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM SLC11A1 SYK PLEK FYB1 ALOX5 SORL1	2.59e-06	162	166	7	4e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR2 GJB4 LAMA3 ST3GAL4 TGM3 FLRT1 HOXB13	3.29e-06	168	166	7	03896466698a79f7f1ad862cb7e05585260e2a5a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DNAH1 ATXN1 ELMO2 AASS TOMM40 FYB1 IL6ST	3.56e-06	170	166	7	adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 MGAM VSIG4 OBSCN SLC11A1 SYK FYB1	3.56e-06	170	166	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM LASP1 THBS1 ARAP3 SVIL ALOX5 SORL1	3.70e-06	171	166	7	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM LASP1 THBS1 ARAP3 SVIL ALOX5 SORL1	3.70e-06	171	166	7	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD4 PRSS12 LAMA2 GRB7 RIT2 MED12L ANO3	3.99e-06	173	166	7	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK\|GI_small-bowel / Manually curated celltypes from each tissue	MGAM ADAP1 ST3GAL4 PTGDS SYK PLEK SORL1	5.00e-06	179	166	7	535bdfdd990ba9ee3edc8f3ad15297f8fb5a266e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL32 ITGA6 SCML4 ATXN1 FYB1 ATP2B4 SORL1	5.18e-06	180	166	7	d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell	Frontal_cortex-Neuronal-Excitatory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRSS12 DGKZ CSMD2 NRN1 SYT7 ATP2B4 ANO3	5.99e-06	184	166	7	6e17c8151d6dc543de16d804db956c63c3fda414
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL32 OBSCN ITGA6 SCML4 FYB1 IL6ST SORL1	5.99e-06	184	166	7	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THSD4 ST3GAL4 ALX1 NFATC1 VCAN UGDH CMTM5	6.89e-06	188	166	7	9b95730ddd13eb4624321bab3ab4989414977ca3
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VSIG4 ENPP4 THBS1 PNPLA6 SLC11A1 ALOX5 VAT1	7.13e-06	189	166	7	a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	THSD4 OBSCN JAK2 SVIL DIP2C ATP11A ATP2B4	7.13e-06	189	166	7	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FLI1 PTGDS AASS SYK LRP4 CMTM5 FYB1	7.13e-06	189	166	7	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|COPD / Disease state, Lineage and Cell class	VSIG4 THBS1 PNPLA6 SLC11A1 SVIL ALOX5 VAT1	7.38e-06	190	166	7	006e31606d637033bc81333816ee332773d36b08
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FLI1 PTGDS AASS SYK LRP4 CMTM5 FYB1	7.64e-06	191	166	7	a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FLI1 LAMA2 ATP10D ALX1 FAIM2 ANO3	7.90e-06	192	166	7	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	COL19A1 ASH1L ATXN1 SIPA1L1 SVIL RBM6 DIP2C	7.90e-06	192	166	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	COVID-19-kidney-Myeloid\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MGAM SLC11A1 SYK PLEK FYB1 ALOX5 SORL1	7.90e-06	192	166	7	0b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FLI1 LAMA2 ATP10D ALX1 FAIM2 ANO3	7.90e-06	192	166	7	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	wk_08-11-Epithelial-PNS-KCNIP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RIPPLY2 CHRNA3 RIT2 AP3B2 SYT1 FAIM2 CDH9	7.90e-06	192	166	7	53642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYLD IL32 ITGA6 SCML4 FYB1 IL6ST SORL1	8.18e-06	193	166	7	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	VSIG4 ADCY7 SLC11A1 SYK PLEK FYB1 ALOX5	8.46e-06	194	166	7	f09675cd472200363c458952f00d2e41990800ee
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 LAMA2 ATP10D THBS1 ALX1 VCAN SYT1	8.46e-06	194	166	7	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL32 ITGA6 ATXN1 ELMO2 FYB1 IL6ST SORL1	8.46e-06	194	166	7	a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 LAMA2 ATP10D THBS1 ALX1 VCAN SYT1	8.46e-06	194	166	7	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	VSIG4 THBS1 SLC11A1 SIPA1L1 SYK FYB1 ALOX5	8.46e-06	194	166	7	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	VSIG4 ADCY7 SLC11A1 SIPA1L1 SYK FYB1 ALOX5	8.74e-06	195	166	7	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ADCY7 SLC11A1 VCAN PLEK FYB1 ALOX5	8.74e-06	195	166	7	10ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SYK PLEK FYB1 ALOX5	8.74e-06	195	166	7	42bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell	Control-Myeloid\|Control / Disease state, Lineage and Cell class	VSIG4 THBS1 SLC11A1 SIPA1L1 VCAN SYK ALOX5	8.74e-06	195	166	7	46ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 LAMA2 ATP10D THBS1 ALX1 VCAN SYT1	8.74e-06	195	166	7	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VSIG4 THBS1 SLC11A1 VCAN SYK UAP1L1 ALOX5	9.04e-06	196	166	7	a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FLI1 FAT4 LAMA2 ALX1 VCAN SYT1	9.04e-06	196	166	7	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLI1 MAP3K3 SLC11A1 VCAN SYK FYB1 ALOX5	9.04e-06	196	166	7	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FLI1 FAT4 LAMA2 ALX1 VCAN SYT1	9.04e-06	196	166	7	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VSIG4 ADCY7 SLC11A1 SYK PLEK FYB1 ALOX5	9.04e-06	196	166	7	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FAT4 LAMA2 ATP10D THBS1 NFATC1 ANO3	9.35e-06	197	166	7	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ADCY7 SCML4 SYK PLEK FYB1 ALOX5	9.35e-06	197	166	7	0523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SLC11A1 SYK FYB1 ALOX5	9.35e-06	197	166	7	dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SYK PLEK FYB1 ALOX5	9.35e-06	197	166	7	826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FAT4 LAMA2 THBS1 NFATC1 ANO3 IL6ST	9.35e-06	197	166	7	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ADCY7 SCML4 SYK PLEK FYB1 ALOX5	9.35e-06	197	166	7	61ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC11A1 SIPA1L1 VCAN SYK PLEK FYB1 ALOX5	9.35e-06	197	166	7	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 VSIG4 ADCY7 SLC11A1 PLEK FYB1 ALOX5	9.35e-06	197	166	7	6ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADCY7 SLC11A1 VCAN SYK PLEK FYB1 ALOX5	9.35e-06	197	166	7	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FAT4 LAMA2 ATP10D THBS1 NFATC1 ANO3	9.35e-06	197	166	7	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAP3K3 SLC11A1 VCAN SYK FYB1 ALOX5 SORL1	9.35e-06	197	166	7	8b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCell	healthy_donor-Lymphocytic-T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	CYLD IL32 OBSCN ITGA6 SCML4 FYB1 IL6ST	9.35e-06	197	166	7	63d0f06e150e7eb800ecb70e97b9d12a01c84e37
ToppCell	Fetal_29-31_weeks-Immune\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLI1 VSIG4 SLC11A1 SYK PLEK FYB1 ALOX5	9.66e-06	198	166	7	5dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCell	PBMC-Mild-cDC_0\|Mild / Compartment, Disease Groups and Clusters	ZDHHC7 THBS1 SLC11A1 ATXN1 VCAN UAP1L1 SORL1	9.66e-06	198	166	7	fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FAT4 LAMA2 THBS1 NFATC1 ANO3 IL6ST	9.66e-06	198	166	7	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VSIG4 SLC11A1 SYK PLEK FYB1 ALOX5 SORL1	9.66e-06	198	166	7	00a54af5267bfe0eeab6720bf890dc4b6b803bfd
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VSIG4 THBS1 SLC11A1 SYK PLEK FYB1 SORL1	9.66e-06	198	166	7	2e470249edc7cf85bed550795ff84cbef22895c0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ADCY7 SLC11A1 SYK PLEK FYB1 ALOX5	9.66e-06	198	166	7	623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VSIG4 SLC11A1 NFATC1 MED12L PLEK ALOX5 SORL1	9.98e-06	199	166	7	b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	THSD4 FAT4 PRSS12 LAMA2 LRP4 SYT1 CMTM5	9.98e-06	199	166	7	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VSIG4 ENPP4 PNPLA6 SLC11A1 SVIL SYK ALOX5	9.98e-06	199	166	7	fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FLI1 VSIG4 SLC11A1 SYK PLEK FYB1 IL6ST	9.98e-06	199	166	7	4ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
Drug	Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A	APC ITGA6 JAK2 THBS1 ATXN1 PIK3C2B SVIL SYT1 SLC23A2 HOXB13	8.15e-07	177	168	10	4652_DN
Drug	forskolin; Up 200; 50uM; MCF7; HT_HG-U133A_EA	LAMA3 ST3GAL4 THBS1 ATXN1 HOXD13 SIPA1L1 SVIL ATP11A IL6ST	2.60e-06	157	168	9	913_UP
Drug	Vistar	RBMY1A1 RBMY1D RBMY1B RBMY1E VCAN	6.46e-06	36	168	5	CID000040896
Drug	mag-fura-2	MGAM RIT2 ITPR3 MORF4L1 ATP2B4	7.42e-06	37	168	5	CID000123839
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT_HG-U133A	SIN3B APC GRB7 ENPP4 VPS13D PNPLA6 SLC12A9 AKAP10 ATP2B4	1.33e-05	192	168	9	7427_DN
Drug	Diperodon hydrochloride [537-12-2]; Up 200; 9.2uM; HL60; HG-U133A	CYLD FLII SFSWAP VPS13D AKT1 PAX1 SLC23A2 ATP2B4 KLC1	1.51e-05	195	168	9	1575_UP
Drug	hydantoin-5-propionic acid	RBMY1A1 RBMY1D RBMY1B RBMY1E	1.55e-05	21	168	4	CID000000782
Disease	factor VIII measurement, venous thromboembolism	DGKZ ST3GAL4 LRP4 FGG PLEK	1.11e-06	34	161	5	EFO_0004286, EFO_0004630
Disease	venous thromboembolism, tissue plasminogen activator measurement	DGKZ LRP4 FGG PLEK	6.97e-06	23	161	4	EFO_0004286, EFO_0004791
Disease	platelet crit	FLI1 ST3GAL4 JAK2 ZGPAT TGM3 THBS1 ARHGEF40 SVIL NECTIN2 SYK RCOR3 RP1 GAPDHS PLEK FYB1 ATP2B4 SORL1	1.92e-05	952	161	17	EFO_0007985
Disease	factor XI measurement, venous thromboembolism	DGKZ LRP4 FGG PLEK	2.09e-05	30	161	4	EFO_0004286, EFO_0004694
Disease	Syndactyly Cenani Lenz type	APC LRP4	2.96e-05	2	161	2	C1859309
Disease	Stuve-Wiedemann syndrome	LIFR IL6ST	2.96e-05	2	161	2	cv:C0796176
Disease	cortical thickness	THSD4 FLII DCDC1 ASIC2 PRSS12 STRBP LAMA2 ME2 RIT2 THBS1 VPS13D ARHGEF40 ALX1 VCAN LRP4 SYT1 AKAP10 USP35	3.97e-05	1113	161	18	EFO_0004840
Disease	Acute Myeloid Leukemia, M1	VSIG4 ADCY7 JAK2 ASMTL SVIL NECTIN2	6.60e-05	125	161	6	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	VSIG4 ADCY7 JAK2 ASMTL SVIL NECTIN2	6.60e-05	125	161	6	C1879321
Disease	Malignant neoplasm of breast	COL19A1 PCDHGB6 STRBP PDZK1 OBSCN LAMA2 GRB7 THBS1 NSUN6 ARAP3 SIPA1L1 NECTIN2 DIP2C AKT1 HOXB13 GOLGB1 SORL1	8.54e-05	1074	161	17	C0006142
Disease	Schwartz-Jampel syndrome	LIFR IL6ST	8.84e-05	3	161	2	cv:C0036391
Disease	interleukin-6 receptor subunit beta measurement	ST3GAL4 IL6ST	8.84e-05	3	161	2	EFO_0801732
Disease	Schizophrenia	PDZK1 APC LAMA2 LASP1 CSMD2 NRN1 ME2 CHRNA3 ADCY7 SYNGAP1 LIFR THBS1 GLO1 AKT1 NKAPL	1.05e-04	883	161	15	C0036341
Disease	urate measurement	DCDC1 PDZK1 ASH1L DNAH1 THBS1 HOXD13 NECTIN2 RBM6 LRP4 SYT1 FLRT1 FAIM2 UBE2W KLC1 KLB	1.22e-04	895	161	15	EFO_0004531
Disease	Coloboma of lens	SALL2 FZD5	1.76e-04	4	161	2	C0344516
Disease	cutaneous leishmaniasis (is_implicated_in)	IL32 SLC11A1	1.76e-04	4	161	2	DOID:9111 (is_implicated_in)
Disease	Coloboma of eyelid	SALL2 FZD5	1.76e-04	4	161	2	C0521573
Disease	Congenital myotonia	LIFR IL6ST	1.76e-04	4	161	2	cv:CN295225
Disease	Congenital coloboma of iris	SALL2 FZD5	2.93e-04	5	161	2	C0266551
Disease	Coloboma of optic disc	SALL2 FZD5	2.93e-04	5	161	2	C0155299
Disease	odorant-binding protein 2b measurement	OBP2B OBP2A	2.93e-04	5	161	2	EFO_0801859
Disease	Coloboma of choroid and retina	SALL2 FZD5	2.93e-04	5	161	2	C4708599
Disease	bacterial gastritis (is_marker_for)	IL32 JAK2	2.93e-04	5	161	2	DOID:4033 (is_marker_for)
Disease	Hereditary macular coloboma	SALL2 FZD5	2.93e-04	5	161	2	C1852767
Disease	hepatocellular carcinoma (biomarker_via_orthology)	SF3B4 JAK2 RGN AKT1 IL6ST	3.22e-04	108	161	5	DOID:684 (biomarker_via_orthology)
Disease	aspartate aminotransferase to alanine aminotransferase ratio	OBP2B ARHGAP39 SCAF4 NECTIN2 TOMM40 RP1 HEPHL1	3.55e-04	239	161	7	EFO_0010934
Disease	creatinine measurement	DCDC1 OBSCN LAMA2 STAC2 NFATC1 SVIL AP3B2 NECTIN2 DIP2C SYT1 RCOR3 TOMM40 FAIM2 SLC23A2 SORL1	3.79e-04	995	161	15	EFO_0004518
Disease	Leukemia, Myelocytic, Acute	VSIG4 ADCY7 JAK2 ASMTL SVIL NECTIN2	3.87e-04	173	161	6	C0023467
Disease	Rheumatoid Arthritis	ITGA6 SLC11A1 HOXD13 PLEK ALOX5 IL6ST	3.99e-04	174	161	6	C0003873
Disease	right ventricular ejection fraction measurement	OBSCN SVIL SLC23A2	5.81e-04	30	161	3	EFO_0021816
Disease	Prostatic Neoplasms	PDZK1 ASH1L APC GRB7 JAK2 LIFR NECTIN2 AKT1 ALOX5 HOXB13 IL6ST	5.96e-04	616	161	11	C0033578
Disease	Malignant neoplasm of prostate	PDZK1 ASH1L APC GRB7 JAK2 LIFR NECTIN2 AKT1 ALOX5 HOXB13 IL6ST	5.96e-04	616	161	11	C0376358
Disease	junctional epidermolysis bullosa (is_implicated_in)	LAMA3 ITGA6	6.10e-04	7	161	2	DOID:3209 (is_implicated_in)
Disease	immunoglobulin superfamily containing leucine-rich repeat protein 2 measurement	OBP2B ST3GAL4	6.10e-04	7	161	2	EFO_0021879
Disease	Polysyndactyly	HOXD13 LRP4	6.10e-04	7	161	2	C0265553
Disease	stomach cancer (is_implicated_in)	IL32 APC CHRNA3 JAK2	6.58e-04	72	161	4	DOID:10534 (is_implicated_in)
Disease	cesarean section, anxiety	ATXN1 DIP2C	8.11e-04	8	161	2	EFO_0005230, EFO_0009636
Disease	Syndactyly	HOXD13 LRP4	8.11e-04	8	161	2	C0039075
Disease	serum alanine aminotransferase measurement	IL32 ARHGAP39 ATP10D ZGPAT THBS1 MORF4L1 NECTIN2 RBM6 TOMM40 RP1 USP35 HEPHL1 ALOX5	1.00e-03	869	161	13	EFO_0004735
Disease	Mental deterioration	NECTIN2 SORL1	1.04e-03	9	161	2	C0234985
Disease	Mild cognitive disorder	NECTIN2 SORL1	1.04e-03	9	161	2	C1270972
Disease	visceral leishmaniasis (is_implicated_in)	IL32 SLC11A1	1.04e-03	9	161	2	DOID:9146 (is_implicated_in)
Disease	hepatocyte growth factor-like protein measurement	FBXW12 DNAH1 RBM6	1.17e-03	38	161	3	EFO_0008154
Disease	free cholesterol in medium LDL measurement	ST3GAL4 NECTIN2 TOMM40	1.36e-03	40	161	3	EFO_0022268
Disease	depressive symptom measurement, response to antidepressant	DIP2C SYT1 ATP2B4 GOLGB1	1.39e-03	88	161	4	EFO_0007006, GO_0036276
Disease	venous thromboembolism, von Willebrand factor measurement	ST3GAL4 FGG PLEK	1.57e-03	42	161	3	EFO_0004286, EFO_0004629
Disease	pulmonary tuberculosis (is_implicated_in)	SLC11A1 AKT1 ALOX5	1.57e-03	42	161	3	DOID:2957 (is_implicated_in)
Disease	concentration of large LDL particles measurement	ST3GAL4 NECTIN2 TOMM40	1.79e-03	44	161	3	EFO_0022160
Disease	cholesterol in medium VLDL measurement	ST3GAL4 NECTIN2 TOMM40	1.79e-03	44	161	3	EFO_0022225
Disease	cerebral amyloid deposition measurement	ARAP3 ATXN1 NECTIN2 TOMM40	1.85e-03	95	161	4	EFO_0007707
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR3 ATXN1	1.88e-03	12	161	2	DOID:1441 (implicated_via_orthology)
Disease	Malignant neoplasm of salivary gland	PDZK1 ST3GAL4 VCAN	1.91e-03	45	161	3	C0220636
Disease	total lipids in small LDL	ST3GAL4 NECTIN2 TOMM40	2.17e-03	47	161	3	EFO_0022168
Disease	Salivary Gland Neoplasms	PDZK1 ST3GAL4 VCAN	2.17e-03	47	161	3	C0036095
Disease	free cholesterol in small VLDL measurement	ST3GAL4 NECTIN2 TOMM40	2.17e-03	47	161	3	EFO_0022272
Disease	free cholesterol in medium VLDL measurement	ST3GAL4 NECTIN2 TOMM40	2.17e-03	47	161	3	EFO_0022269
Disease	Cakut	CHRNA3 LIFR	2.22e-03	13	161	2	C1968949
Disease	Familial Alzheimer Disease (FAD)	NECTIN2 TOMM40 GAPDHS SORL1	2.23e-03	100	161	4	C0276496
Disease	Adenoid Cystic Carcinoma	PDZK1 ST3GAL4 MORF4L1 VCAN	2.23e-03	100	161	4	C0010606
Disease	Alzheimer's Disease	NECTIN2 TOMM40 GAPDHS SORL1	2.31e-03	101	161	4	C0002395
Disease	pancreatic cancer (is_marker_for)	SF3B4 THBS1 AKT1 ALOX5	2.31e-03	101	161	4	DOID:1793 (is_marker_for)
Disease	physical activity measurement	APC RIT2 SIPA1L1 NECTIN2 AKAP10 ATP2B4	2.33e-03	245	161	6	EFO_0008002
Disease	complement factor H-related protein 3 measurement	VPS37A CPXCR1 LIFR NFATC1 DIP2C	2.40e-03	169	161	5	EFO_0600056
Disease	phospholipids in medium LDL measurement	ST3GAL4 NECTIN2 TOMM40	2.44e-03	49	161	3	EFO_0022183
Disease	apolipoprotein B to apolipoprotein A1 ratio	ST3GAL4 NECTIN2 TOMM40	2.44e-03	49	161	3	EFO_0021897
Disease	cholesterol in medium LDL measurement	ST3GAL4 NECTIN2 TOMM40	2.44e-03	49	161	3	EFO_0022224
Disease	cholesterol in small LDL measurement	ST3GAL4 NECTIN2 TOMM40	2.44e-03	49	161	3	EFO_0022227
Disease	developmental disorder of mental health (implicated_via_orthology)	SIN3B ASH1L SYNGAP1	2.44e-03	49	161	3	DOID:0060037 (implicated_via_orthology)
Disease	Impaired cognition	NECTIN2 SORL1	2.58e-03	14	161	2	C0338656
Disease	free cholesterol in LDL measurement	ST3GAL4 NECTIN2 TOMM40	2.59e-03	50	161	3	EFO_0022266
Disease	free cholesterol in large LDL measurement	ST3GAL4 NECTIN2 TOMM40	2.74e-03	51	161	3	EFO_0022176
Disease	phospholipids in IDL measurement	ST3GAL4 NECTIN2 TOMM40	2.90e-03	52	161	3	EFO_0022164
Disease	total lipids in medium LDL	ST3GAL4 NECTIN2 TOMM40	2.90e-03	52	161	3	EFO_0022180
Disease	total lipids in LDL measurement	ST3GAL4 NECTIN2 TOMM40	2.90e-03	52	161	3	EFO_0022308
Disease	phospholipids in large LDL measurement	ST3GAL4 NECTIN2 TOMM40	3.06e-03	53	161	3	EFO_0022174
Disease	cholesterol in small VLDL measurement	ST3GAL4 NECTIN2 TOMM40	3.06e-03	53	161	3	EFO_0022228
Disease	free cholesterol in small LDL measurement	ST3GAL4 NECTIN2 TOMM40	3.06e-03	53	161	3	EFO_0022271
Disease	Autistic Disorder	ASIC2 APC LASP1 SYNGAP1 GLO1 CDH9	3.18e-03	261	161	6	C0004352
Disease	pancreatic cancer (is_implicated_in)	APC THBS1 AKT1 ALOX5	3.36e-03	112	161	4	DOID:1793 (is_implicated_in)
Disease	vitamin C measurement	AKT1 SLC23A2	3.38e-03	16	161	2	EFO_0600003
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA3 SYT1	3.38e-03	16	161	2	DOID:3635 (implicated_via_orthology)
Disease	digit length ratio	FLI1 HOXD13	3.38e-03	16	161	2	EFO_0004841
Disease	Polyposis, Adenomatous Intestinal	APC AKT1	3.38e-03	16	161	2	C2713442
Disease	Familial Intestinal Polyposis	APC AKT1	3.38e-03	16	161	2	C2713443
Disease	pneumonia, COVID-19	COPG1 ASIC2 UGDH ANO3	3.47e-03	113	161	4	EFO_0003106, MONDO_0100096
Disease	total lipids in large LDL	ST3GAL4 NECTIN2 TOMM40	3.76e-03	57	161	3	EFO_0022163
Disease	cholesterol in large LDL measurement	ST3GAL4 NECTIN2 TOMM40	3.76e-03	57	161	3	EFO_0021901
Disease	Carcinoma, Granular Cell	FAT4 APC GRB7 ALOX5	3.81e-03	116	161	4	C0205644
Disease	Adenocarcinoma, Tubular	FAT4 APC GRB7 ALOX5	3.81e-03	116	161	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	FAT4 APC GRB7 ALOX5	3.81e-03	116	161	4	C0205642
Disease	Carcinoma, Cribriform	FAT4 APC GRB7 ALOX5	3.81e-03	116	161	4	C0205643
Disease	Adenocarcinoma, Basal Cell	FAT4 APC GRB7 ALOX5	3.81e-03	116	161	4	C0205641
Disease	Adenocarcinoma	FAT4 APC GRB7 ALOX5	3.81e-03	116	161	4	C0001418
Disease	heart disease (biomarker_via_orthology)	JAK2 THBS1	3.81e-03	17	161	2	DOID:114 (biomarker_via_orthology)
Disease	ulcerative colitis (is_implicated_in)	JAK2 SLC11A1	3.81e-03	17	161	2	DOID:8577 (is_implicated_in)
Disease	Adenomatous Polyposis Coli	APC AKT1	3.81e-03	17	161	2	C0032580
Disease	HMG CoA reductase inhibitor use measurement	ST3GAL4 ITPR3 NECTIN2 TOMM40 RP1	3.87e-03	189	161	5	EFO_0009932
Disease	venous thromboembolism	DGKZ ST3GAL4 RIT2 ITPR3 ARNT2 LRP4 FGG PLEK	3.88e-03	460	161	8	EFO_0004286
Disease	cholesterol in IDL measurement	ST3GAL4 NECTIN2 TOMM40	3.95e-03	58	161	3	EFO_0021899
Disease	phospholipids in LDL measurement	ST3GAL4 NECTIN2 TOMM40	3.95e-03	58	161	3	EFO_0022294

Protein segments in the cluster

Peptide	Gene	Start	Entry
KSPPSKNSDFYMGAG	ALX1	11	Q15699
KDGATMKTFCGTPEY	AKT1	301	P31749
YCTSPDFKMGGASDV	ASH1L	526	Q9NR48
SKLKGPEGGSEMFVY	ARHGEF40	1301	Q8TER5
FTYPKGAGEMLEDGS	ANAPC16	36	Q96DE5
SLMYFGSDKDPFPKG	ARAP3	316	Q8WWN8
APKNGMVFGKEYTVG	CSMD2	2536	Q7Z408
KMGKAGVRTYGFRSP	VCAN	221	P13611
SDYGGAEFMRVPAQK	CHRNA3	101	P32297
TYAGKMTFGRVSDLG	AKAP10	581	O43572
EDGKMIPASQYFSTG	ALDH1L2	316	Q3SY69
SAMDKDSGPNGQLDY	FAT4	2691	Q6V0I7
YGDINGFSAMAKTVG	AASS	861	Q9UDR5
GIVGAKSPYVDDMGA	CACHD1	1066	Q5VU97
PSGVVMEGYLFKRAS	ACAP3	266	Q96P50
EGYMEKTGPKQTEGF	ADAP1	256	O75689
MPAKGRYFLNEGEEG	ADCY7	1	P51828
GEMEKSRRYGAPSSA	ATXN1	326	P54253
NPNGGFRMYSKGASE	ATP2B4	581	P23634
DQGYSETKAFEMAGP	ATP10D	1406	Q9P241
MDKGQRDPYSGNAFL	BEND6	36	Q5SZJ8
DMNYIASSGPLFKDG	ANO3	146	Q9BYT9
MSAAPAYSEDKGGSA	AP3B2	1	Q13367
MRGTGNKSTDGAYKP	ARNT2	116	Q9HBZ2
GKCYMFNSGEDGKPL	ASIC2	191	Q16515
MSYPTKEGSDTAGNA	CPXCR1	1	Q8N123
FGSKAPGPAMYERVS	MSANTD2	136	Q6P1R3
DDGGYTPDLKMSYSR	RBMY1A1	131	P0DJD3
DDGGYTPDLKMSYSR	RBMY1B	131	A6NDE4
DDGGYTPDLKMSYSR	RBMY1C	131	P0DJD4
DDGGYTPDLKMSYSR	RBMY1D	131	P0C7P1
DDGGYTPDLKMSYSR	RBMY1E	131	A6NEQ0
DDGGYTPDLKMSYSR	RBMY1F	131	Q15415
PGATKYTDKDNGGML	RCOR3	16	Q9P2K3
YKPFGKEAAGTMTLS	RBM41	56	Q96IZ5
LGVKSGDYSTMEGPE	ARHGAP39	441	Q9C0H5
GKGNFGSVEMCRYDP	JAK2	856	O60674
PSYKGDASDPKAAGM	ITPR3	321	Q14573
PYFSLMVRVNSDGGK	PCDHGB6	176	Q9Y5F9
PRIVEMKKGSNGYGF	PDZK1	241	Q5T2W1
EQYAEGKMRGAAPGK	MORF4L1	121	Q9UBU8
SGLQGGPRSDFDMAY	PNPLA6	426	Q8IY17
EGFSPSGAKMYIQGV	DCDC1	376	M0R2J8
PARARTMAYFGEGKG	PRSS12	546	P56730
EETYKKFSGAMDGAP	NKX2-4	21	Q9H2Z4
KGGYFPENVKAMTSL	FLII	21	Q13045
PSYEEATSGEGMKAG	FAIM2	36	Q9BWQ8
NASPGGSEENKRAYM	MED12L	1586	Q86YW9
DSGGPIFKSPQTYMD	LAMA3	2831	Q16787
FSYGQKPYRGMKGSE	SYK	566	P43405
SGEPMDKAGGYGIQA	ASMTL	166	O95671
SSKPYGPYDRGSDMK	MGAM	461	O43451
KYHEEFEKSRMGPSG	LASP1	121	Q14847
NYEAYKPSTGAMGDR	DDX42	681	Q86XP3
YLTKDGPFLMVGDAA	FBXW12	196	Q6X9E4
GKMKGLAFIQDPDGY	GLO1	156	Q04760
SGHKYGPEDKENMSR	ENPP4	191	Q9Y6X5
MAKYNTGGNPTEDVS	FYB1	1	O15117
PRAGGTMKSAEEEHY	NFATC1	31	O95644
MTGDKGPQRLSGSSY	SLC11A1	1	P49279
GDSMANYPQGLDDKT	NRN1	46	Q9NPD7
GCMGETYFDNKPIGL	LAMA2	2301	P24043
KYGDPGSLFGFSLAM	ITGA6	36	P23229
MEAAGSPAATETGKY	PYM1	1	Q9BRP8
MELFRIGGKSPDTNY	PPP2CB	66	P62714
IGGKSPDTNYLFMGD	PPP2CB	71	P62714
MELFRIGGKSPDTNY	PPP2CA	66	P67775
IGGKSPDTNYLFMGD	PPP2CA	71	P67775
YAPGIVSASQFMKAG	NSUN6	131	Q8TEA1
MRKTEEPGKFSAYGG	OBP2A	81	Q9NY56
VTQGRKLYGMPTDFG	GRB7	286	Q14451
FTSDMAYVINGGDKP	PIK3C2B	1236	O00750
AGPKYEMRSQGATRE	OBSCN	4111	Q5VST9
MRKTEEPGKYSAYGG	OBP2B	81	Q9NPH6
GALAGSEGTAYSPKM	PAX1	306	P15863
EYKEGVGKFIGMPES	QTRT2	76	Q9H974
GRTSTADYAMFKVGP	FGG	281	P02679
KSGGAMAAGDYPEAS	FZD5	546	Q13467
GDFMSPGSDVKSYEL	DNAH1	2516	Q9P2D7
MVVYDPDKGSNGTFL	CDHR2	391	Q9BYE9
MSSFQSYGAPRGDKE	IL32	206	P24001
RMAAYTDEGGKDGPE	IL6ST	591	P40189
SNAPGSGTEKRKAMY	ELMO2	331	Q96JJ3
AGEPGKYDSMARKGD	COL19A1	716	Q14993
GEPVGDDYKKMGTLF	FAM241A	61	Q8N8J7
PPSFGYSMKGATDID	ITGAV	431	P06756
YSMKGATDIDKNGYP	ITGAV	436	P06756
KADMTASGSPDYGQP	FLI1	31	Q01543
GFPVEKYMDVSGLAS	HOXD13	161	P35453
NVFSYEMDGPEGSTK	GALNTL5	286	Q7Z4T8
VLMKAGSAPVDAGGY	GJB4	251	Q9NTQ9
RTAPKYGNAELMETG	DIP2C	231	Q9Y2E4
GDGTYGSVLMGKSNE	MAK	11	P20794
YGQLGTGDKMDRGEP	FBXO24	386	O75426
LYPDGTSGRNKNDDM	HEPHL1	141	Q6MZM0
GTDNIALLKDPFYMG	ME2	206	P23368
GDGDYPEGMRKKLFS	KLB	336	Q86Z14
KDMTGKEDNYRGPAV	COPG1	111	Q9Y678
FDLSQGGPKEALEMY	DGKZ	326	Q13574
SNIDYPMATGDGAKT	FLRT1	396	Q9NZU1
PGKESLGYFVGVDMD	CYLD	256	Q9NQC7
AAAKGPMAGILAYTE	GAPDHS	336	O14556
MEPGNYATLDGAKDI	HOXB13	1	Q92826
AESGDSVKMYGSAVP	SCAF4	796	O95104
KNGSGELSYGEVMGP	SALL2	351	Q9Y467
GPRFKKLADMYGGDD	CDH9	771	Q9ULB4
KYESGPDGGEEVSMS	KLC1	531	Q07866
LRAYTDGGVGPEKSM	LIFR	811	P42702
MPGGSVKDQLKAYGA	MAP3K3	446	Q99759
FPSDGYGVDQTSMNK	RP1	1281	P56715
LPVGYEAEMSSKGAG	FER1L6	796	Q2WGJ9
PEGQDYLKGMAAAGN	RTCB	301	Q9Y3I0
ALDMGGTSDPYVKVF	SYT1	171	P21579
RNLKAMDIGGTSDPY	SYT7	291	O43581
NFTGKAEMGGPFSYV	TMEM106C	186	Q9BVX2
GEMPKFDGAGYDKDL	KATNAL1	176	Q9BW62
SQMFGYGQSKSFPEG	RBM6	416	P78332
GDLKPGIYRSNMDGS	SORL1	896	Q92673
MYGASGGRAKPERKS	SFSWAP	1	Q12872
SSVVKGRFMGDPSYE	RSPH9	96	Q9H1X1
GEGPYDMVFQKGDSV	STK16	231	O75716
LTGRDSGMEKYGSFE	SVIL	956	O95425
MVVFGYEAGTKPRDS	TMEM126B	1	Q8IUX1
YGMRGRKSSGFPKSV	ALOX5	516	P09917
PGSASGGSREYKVVM	RIT2	11	Q99578
GAGKTYTMEGTAENP	KIFC3	531	Q9BVG8
SPSSFVDKGMSYIVG	NT5DC3	301	Q86UY8
NEGYLQPAGDMSKSA	PLEK	186	P08567
KMEAYGGQLGSFPTS	TBX15	461	Q96SF7
LYSQGSKGPGEDFRM	PTGDS	131	P41222
SKGPGEDFRMATLYS	PTGDS	136	P41222
IYGGDGLDPAAMEGK	POLR3A	901	O14802
SVGGTYRQKSMPEGF	SIPA1L1	1161	O43166
PVAGYEGDVGSKTTM	ST3GAL4	151	Q11206
EGDVGSKTTMRLFYP	ST3GAL4	156	Q11206
GSDPATYNGFLEIMK	SIN3B	56	O75182
KVLQAMGYPTGFDAD	STRBP	446	Q96SI9
KVDPAGRYFAGTMAE	RGN	106	Q15493
LAFMDLGYSTTVGPK	OR8K3	66	Q8NH51
VYYDPMGNPLDKGSD	TGM3	311	Q08188
DGYGKRGQMKPSIES	APC	971	P25054
GKSPDYANGGKAAMD	CSNK1G2-AS1	61	Q8NCQ2
FKIYRTEMAPGASQG	CMTM5	206	Q96DZ9
SLIMKPREDGSSGNY	ATP11A	766	P98196
LPGEGAAMAEYVKAG	NKAPL	301	Q5M9Q1
ASKDGQPYDMGGSAK	RECQL5	611	O94762
TPTKTYGMGKGRAAD	UGDH	91	O60701
AAGYDGKAFGSPMID	TRIM24	596	O15164
IMADSGPIYDKTYAG	THBS1	1131	P07996
RRKSVPGGKQYSMEG	SYNGAP1	106	Q96PV0
GNKSLDGMESYNLPF	SLC23A2	591	Q9UGH3
PYSFTPMLEEGAGSK	PYROXD2	116	Q8N2H3
MYAKGGKGSAVPSDS	SSBP4	1	Q9BWG4
PFSGNKEQGYMSLKE	STAC2	361	Q6ZMT1
DGPGMTAASGKLYQF	RIPPLY2	61	Q5TAB7
AGFYPRLMAKSDTGK	USP35	426	Q9P2H5
GMKPNTLVLGFYDDA	SLC12A9	621	Q9BXP2
KDKVAMAPDGNGGLY	UAP1L1	216	Q3KQV9
DMDGYLGETSAGPGK	VSIG4	266	Q9Y279
CETENPMGGYGKTIS	RUVBL1	141	Q9Y265
GFNTKMADGPDEYDT	ZDHHC17	6	Q8IUH5
PGEEGTVMSLAGKYT	TOMM40	241	O96008
MDPLGGSDTAKGYNL	VAT1	261	Q99536
GAVPKGNATKEYMES	ZDHHC7	106	Q9NXF8
MEGAPGTLYEGEKFQ	UBE2W	41	Q96B02
EGGGTMFTYKRPNEI	THSD4	476	Q6ZMP0
YGGEMVSVSASFDGK	SCML4	156	Q8N228
KIMRDPDTGNSKGYA	SF3B4	131	Q15427
EAGAAPAGRRSKDMY	ZGPAT	431	Q8N5A5
SQNGFGYKMPDVPDA	VPS37A	216	Q8NEZ2
AFDTRYAGQKTSPGM	VPS13D	2341	Q5THJ4
SSGLKQNYDEMSPAG	GOLGB1	956	Q14789
KSKFTDPGMGNLTYS	LRP4	1751	O75096
PSDSYQGKGFVMSRA	NECTIN2	521	Q92692