Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

SMARCD2 NCOA6 KMT2D ATN1 SS18

2.94e-04303395GO:0003713
GeneOntologyCellularComponentMLL3/4 complex

NCOA6 KMT2D

2.33e-0412402GO:0044666
DomainZnf_FYVE_PHD

FGD1 KMT2D PHF23

3.05e-03147373IPR011011
DomainQuinoprotein_ADH-like_supfam

EML2 WDR90

4.94e-0353372IPR011047
DomainPHD

KMT2D PHF23

9.68e-0375372PF00628
DomainPH

FGD1 RAPH1 DOK3

1.04e-02229373PF00169
DomainZnf_PHD-finger

KMT2D PHF23

1.07e-0279372IPR019787
DomainPHD

KMT2D PHF23

1.34e-0289372SM00249
DomainZnf_PHD

KMT2D PHF23

1.40e-0291372IPR001965
DomainWD40

EML2 WDR90 WRAP53

1.45e-02259373PF00400
DomainZF_PHD_2

KMT2D PHF23

1.52e-0295372PS50016
DomainZF_PHD_1

KMT2D PHF23

1.55e-0296372PS01359
DomainWD40

EML2 WDR90 WRAP53

1.58e-02268373SM00320
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

SMARCD2 NCOA6 KMT2D SS18 TET3

1.07e-04254275M27131
Pubmed

The granulocyte-colony stimulating factor receptor (G-CSFR) interacts with retinoic acid receptors (RARs) in the regulation of myeloid differentiation.

RARG CSF3R

3.87e-06340223136256
Pubmed

Lysine methyltransferase 2D regulates muscle fiber size and muscle cell differentiation.

KMT2D DMD

3.87e-06340234613626
Pubmed

Liganded RARalpha and RARgamma interact with but are repressed by TNIP1.

TNIP1 RARG

3.87e-06340219732752
Pubmed

G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy.

DMD CSF3R

7.73e-06440225865621
Pubmed

Barx2 is expressed in satellite cells and is required for normal muscle growth and regeneration.

BARX2 DMD

1.29e-05540222076929
Pubmed

Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.

NCOA6 KMT2D

1.93e-05640217021013
Pubmed

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.

NCOA6 KMT2D

2.70e-05740219556342
Pubmed

Human transcription factor protein interaction networks.

SMARCD2 TNIP1 NCOA6 KMT2D ATN1 PHF23 SS18 MRPS18B SEC24A

2.81e-05142940935140242
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

SMARCD2 NCOA6 KMT2D SS18

3.22e-0515740430186101
Pubmed

Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.

NCOA6 KMT2D

3.60e-05840217178841
Pubmed

miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway.

SMARCD2 DMD

8.45e-051240225689854
Pubmed

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.

NCOA6 KMT2D

9.98e-051340217761849
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

NCOA6 KMT2D

1.16e-041440212482968
Pubmed

The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.

NCOA6 KMT2D

1.34e-041540217925232
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

NCOA6 KMT2D

1.53e-041640224368734
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TOM1L2 TNIP1 KIAA1191 DMD RAPH1 ENKD1 SEC24A

1.63e-04103840726673895
Pubmed

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.

NCOA6 KMT2D

1.73e-041740226180087
Pubmed

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

NCOA6 KMT2D

1.95e-041840217500065
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ENGASE EML2 NCOA6 WDR90 KMT2D RARG WRAP53

2.39e-04110540735748872
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOA6 KMT2D ATN1 WRAP53 RAPH1 SIPA1L1

2.40e-0477440615302935
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

NCOA6 KMT2D

2.42e-042040229785026
Pubmed

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.

NCOA6 KMT2D

2.42e-042040219047629
Pubmed

FBXW7 Triggers Degradation of KMT2D to Favor Growth of Diffuse Large B-cell Lymphoma Cells.

NCOA6 KMT2D

2.42e-042040232350066
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

SMARCD2 NCOA6 KMT2D ATN1

2.53e-0426840433640491
Pubmed

Control of lens development by Lhx2-regulated neuroretinal FGFs.

ETV1 FGF19

2.67e-042140227633990
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

NCOA6 KMT2D

2.94e-042240226886794
Pubmed

The function of FGF signaling in the lens placode.

ETV1 FGF19

3.21e-042340221223962
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

SMARCD2 SS18

3.21e-042340230962207
Pubmed

Repression of Fgf signaling by sprouty1-2 regulates cortical patterning in two distinct regions and times.

ETV1 FGF19

3.50e-042440220237272
Pubmed

Patterning the dorsal telencephalon: a role for sonic hedgehog?

ETV1 FGF19

3.80e-042540217959802
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NCOA6 KIAA1191 RAPH1 ENKD1 SEC24A SIPA1L1

4.23e-0486140636931259
Pubmed

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

SMARCD2 SS18

4.45e-042740229374058
Pubmed

Foxg1 deletion impairs the development of the epithalamus.

ETV1 FGF19

4.45e-042740229394901
Pubmed

Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.

ETV1 FGF19

5.13e-042940220615956
Pubmed

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.

SMARCD2 RAPH1 PHF23 MRPS18B

5.31e-0432640417015433
Pubmed

Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis.

ETV1 FGF19

6.26e-043240229028795
Pubmed

Interaction network of human early embryonic transcription factors.

SMARCD2 NCOA6 KMT2D ATN1

7.00e-0435140438297188
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

TOM1L2 RELL2 ZDHHC9 FGF19 ENKD1 FCHSD1

8.57e-0498540612975309
Pubmed

Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

TNIP1 TET3

8.83e-043840223273568
Pubmed

Parcellation of the striatal complex into dorsal and ventral districts.

ETV1 FGF19

1.08e-034240232170006
InteractionTBXT interactions

SMARCD2 NCOA6 KMT2D ATN1 SS18

2.85e-06116395int:TBXT
InteractionFOS interactions

SMARCD2 NCOA6 KMT2D BARX2 SS18 ENKD1

2.78e-05312396int:FOS
InteractionSOX17 interactions

SMARCD2 NCOA6 KMT2D SS18

3.36e-0595394int:SOX17
InteractionKLF5 interactions

SMARCD2 NCOA6 KMT2D SS18 MRPS18B

3.55e-05195395int:KLF5
InteractionSS18L1 interactions

SMARCD2 ATN1 SS18 C1orf94

3.79e-0598394int:SS18L1
InteractionERG interactions

ETV1 SMARCD2 NCOA6 KMT2D SS18

6.72e-05223395int:ERG
InteractionDMPK interactions

RARG ATN1 CSF3R

6.79e-0541393int:DMPK
InteractionPAX9 interactions

SMARCD2 NCOA6 KMT2D ATN1

1.14e-04130394int:PAX9
InteractionCXXC1 interactions

NCOA6 KMT2D ATN1 TET3

1.21e-04132394int:CXXC1
Cytoband5q31.3

RELL2 FCHSD1

4.58e-04364025q31.3
CytobandEnsembl 112 genes in cytogenetic band chr5q31

RELL2 SEC24A FCHSD1

2.24e-03298403chr5q31
GeneFamilyWD repeat domain containing

EML2 WDR90 WRAP53

4.30e-03262233362
GeneFamilyPHD finger proteins

KMT2D PHF23

5.79e-039023288
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV1 C1orf94 FGF19 DOK3

1.73e-05173404e944ea3a0a368f856efacbda4600605cf751dd9c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV1 C1orf94 FGF19 DOK3

1.73e-0517340485fa5918e9c1f6bb4757e3350cfc71ee75c55640
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

ETV1 CSF3R ZDHHC9 PHACTR1

2.40e-051884045f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

IL17RA CSF3R TET3 SIPA1L1

2.60e-051924047be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CSF3R TET3 DOK3 PHACTR1

2.60e-051924040219093e7921a0db78053aee13ec480b520f5662
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CSF3R TET3 DOK3 PHACTR1

2.60e-05192404f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

IL17RA CSF3R TET3 SIPA1L1

2.82e-0519640404d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL17RA CSF3R TET3 PHACTR1

2.94e-05198404a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCellCOVID-19_Mild-Classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

IL17RA CSF3R TET3 DOK3

2.94e-0519840430ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCellcritical|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TNIP1 CSF3R DOK3 PHACTR1

3.00e-0519940416c55cb8a0e740342009965f0eddfb0ed2858fab
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BPIFB4 ETV1 WRAP53

2.25e-041324033661665ed5b257f51530122cb9a9c849b5baa1fb
ToppCellfacs-Lung-Endomucin-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

3.41e-04152403962f5bf632da79bd933193d3edd7d89941a85831
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL17RA CSF3R DOK3

3.47e-041534036a2a2379238133ce0ad714af130ffe02dd317247
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL17RA CSF3R DOK3

3.47e-04153403faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCellfacs-Lung-Endomucin-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

3.54e-041544038746663a822d93a8510081c81a8c971b51653067
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

3.54e-0415440327f76e4b3c055aa382708f1610c685f02d6d6114
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL17RA CSF3R DOK3

3.75e-04157403857cd7edc872ade3f0164abefe61600c69d16f58
ToppCellfacs-Lung-24m-Hematologic-myeloid-neutrophil|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

3.75e-04157403e96241db2b5ff52b230e3e33207e7bb968900cab
ToppCellfacs-Lung-24m-Hematologic-myeloid-neutrophil-neutrophil|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

3.75e-0415740307a0f8d29a3111be670eae030a91474465eba734
ToppCellfacs-Lung-Endomucin_-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

3.75e-041574032b60de520edf167f5ca790b478557a778435b3d9
ToppCell10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue

ETV1 SCART1 RARG

3.75e-04157403c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R FCHSD1

3.82e-041584030ed844ab625351a46b74edddf082279ed1bae5c6
ToppCellfacs-Lung-Endomucin-24m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R FCHSD1

3.82e-04158403b3a810314e253b4fd0f578e759c36fdd21722934
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL17RA CSF3R DOK3

3.82e-04158403097a1b719da5c99a7db8531ab45913bd9270b497
ToppCellfacs-Lung-EPCAM-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

3.89e-04159403baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

3.89e-041594039eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

SCART1 WDR90 RAPH1

3.89e-04159403655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellfacs-Lung-Endomucin-24m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

3.89e-04159403886cbaef39a3517514a3896b6b960d01a3af043d
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ETV1 CSF3R ENKD1

3.96e-04160403bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ETV1 CSF3R ENKD1

3.96e-0416040376f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV1 WDR90 KIAA1191

4.03e-04161403deb10628d258fb813c293f81fb71be8e383dc82a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV1 WDR90 KIAA1191

4.03e-041614038aaca49b53a551395f4025ac4e535c7b0ce41a49
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ETV1 GPR135 CSF3R

4.03e-041614031f4614ae15bd2fc08e555cea4d0152c4a940d048
ToppCellfacs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.11e-04162403484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.11e-04162403bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.11e-041624034e7e565091bce227d794a36af2e5dfc4a791efad
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.11e-04162403ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ETV1 RAPH1 TET3

4.11e-0416240364353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.18e-04163403f6c8db5963ee1f8e0c2996f1aeecd58c00e9b099
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ETV1 RAPH1 TET3

4.18e-041634039f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.18e-0416340304152557aae230e9587fcc16cbabf1247cc5b419
ToppCellfacs-Lung-Endomucin-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.18e-041634030644eb8a66d4e944063125c423de66d2393388b1
ToppCellPND01-Immune-Immune_Myeloid|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL17RA CSF3R DOK3

4.18e-04163403ca12d01615be371fe215ec673d4ec787381e0ca6
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.25e-04164403ea2897942ad72fba900c7ab354d6a9e203bf0e4a
ToppCellfacs-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.33e-04165403720649f330382ea2a68c64a5344160a048afb8f1
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNA ECM2 SEC24A

4.41e-0416640337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNA ECM2 SEC24A

4.41e-0416640381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.41e-041664033037bdca38c3a65eacfa644219cc43c54e303749
ToppCellfacs-Lung-Endomucin-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.41e-041664035126d8f02314717eed341d867856fd4fe16c5118
ToppCellwk_20-22-Hematologic-Myeloid-GMP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ENGASE CSF3R TET3

4.41e-04166403d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCellfacs-Lung-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.41e-041664037bf7c2854cf7d85b3ae07256bbe86ae9184d6b57
ToppCelldroplet-Lung-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.49e-041674036f6f654d10cff83203415685f7707409626990ab
ToppCelldroplet-Lung-nan-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.56e-04168403da1eee804456d910c17f145a5ce79c74a808a2c2
ToppCellfacs-Lung-3m-Hematologic-myeloid-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.56e-04168403af4c35c0d3f030cef8397c35fa498a71112bb16b
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.56e-04168403c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCellfacs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.56e-04168403ba9ddd403ee6d6af2fe56dffbd419764bfb703e4
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.56e-041684030ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.56e-04168403c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFLNA BARX2 RELL2

4.64e-0416940346f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCellfacs-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.64e-04169403bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCellfacs-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.64e-0416940305b138511039f1255a5f647040b1b9bdf222bd52
ToppCelldroplet-Lung-21m-Hematologic-myeloid|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.81e-0417140322ad6de44e1d3f72a3d78d46fd26a5743a4f84a5
ToppCelldroplet-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.81e-0417140333869b9fab2c94cb33f1cc659073fcf2bb30c22d
ToppCellfacs-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL17RA CSF3R DOK3

4.81e-041714034ad28ecfde3d529a09b80be908c446bd5274518e
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL17RA CSF3R PHACTR1

4.89e-04172403cf46810dd1072b6f2171e5d9530351ddc79a055b
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL17RA CSF3R DOK3

4.89e-041724030457ccc18697aaec44b7c30ae157aae8f48d8785
ToppCellCOVID-19_Mild-Neu_3|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

KMT2D SEC24A FCHSD1

5.23e-041764032049767fd591045cfcf5b1071d80798e52843f27
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CSF3R DOK3 PHACTR1

5.40e-0417840394a86f5232fffa6a92a30ea21fb44eec33b4d6c8
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV1 GPR135 RFLNA

5.58e-041804039db9899ca42455310e9b63df523fe6c4780abfb7
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

NCOA6 ZDHHC9 FGF19

5.58e-04180403c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ETV1 CSF3R PHACTR1

5.58e-04180403198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL17RA CSF3R DOK3

5.76e-041824031932d77491d6d46278f01fd70eb469ef1b356619
ToppCellfacs-Brain_Non-Myeloid-Striatum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BARX2 CSF3R DOK3

5.85e-04183403824ecda1219fb596a01bf5cfeee29a6daa462098
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL17RA CSF3R DOK3

5.85e-04183403cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ETV1 CSF3R PHACTR1

5.85e-041834036847c1252d6bb105524f812658112517fd351eab
ToppCellcellseq2-Immune-Hematopoietic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL17RA CSF3R DOK3

5.85e-04183403324ec4374b552da7ce03809945b3a0798342d4ba
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BARX2 CSF3R DOK3

5.85e-0418340382b84ee065fb573688d59da97a327152a1ba294c
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RFLNA DMD ECM2

5.95e-041844037128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RFLNA DMD ECM2

5.95e-04184403d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ETV1 CSF3R PHACTR1

5.95e-04184403369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RFLNA DMD ECM2

5.95e-0418440355dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TET3 SIPA1L1 PHACTR1

5.95e-04184403d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ETV1 DMD PHACTR1

6.04e-041854036baccb26f999145e51b91d94315bf8d4655bef31
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IL17RA CSF3R TET3

6.14e-0418640323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

ETV1 CSF3R PHACTR1

6.23e-04187403030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ETV1 RFLNA DMD

6.23e-041874036f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ETV1 CSF3R PHACTR1

6.23e-041874035df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellMS-CD8-CD4_Treg|MS / Condition, Cell_class and T cell subcluster

ENGASE SS18 FCHSD1

6.33e-041884032f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCellControl|World / Disease state, Lineage and Cell class

CSF3R SIPA1L1 PHACTR1

6.43e-04189403fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNIP1 CSF3R ZDHHC9

6.43e-04189403e90ba6f6d7ba0698d04d84278aa035c28803733e
ToppCell3'_v3-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

CSF3R RAPH1 PHACTR1

6.43e-0418940374a5e61cd820f2495dde40e766c771a31d8c4e7d
ToppCellcellseq-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL17RA CSF3R DOK3

6.43e-04189403fedab592be1d6520325b8c1b659b0a4dc3f4fe4d
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL17RA CSF3R SIPA1L1

6.53e-04190403ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNA DMD ECM2

6.53e-041904031004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCellDendritic_cell|World / shred by cell class for nasal brushing

CSF3R DOK3 PHACTR1

6.53e-04190403ae24934f45eea9c228bf6fe8cd0d6abca9eb208e
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFLNA DMD ECM2

6.53e-0419040310b02c62e72bfea9767e3e751011436925da823e
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KMT2D CSF3R FCHSD1

6.53e-041904033f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RFLNA DMD RARG

6.63e-04191403273c4a757292a9301de0eaeacdec91c9866be229
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RARG FGF19 ECM2

6.63e-0419140344b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

ETV1 CSF3R PHACTR1

6.63e-04191403a0332a4ef629510fb313ec119195c44a3f704a80
Diseaseesophagus squamous cell carcinoma (is_marker_for)

KMT2D WRAP53 TET3

1.30e-0474393DOID:3748 (is_marker_for)
DiseaseMalignant neoplasm of breast

TNIP1 NCOA6 KMT2D DMD RARG RAPH1 SIPA1L1

4.60e-041074397C0006142
Diseasetrait in response to apixaban

RFLNA DMD RAPH1

4.76e-04115393OBA_2050328
DiseaseGlobal developmental delay

ATN1 TET3 PHACTR1

7.27e-04133393C0557874
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

EML2 DMD

1.04e-0336392DOID:11723 (implicated_via_orthology)
DiseaseIntellectual Disability

ATN1 ZDHHC9 TET3 PHACTR1

2.81e-03447394C3714756
DiseaseSeizures

ATN1 TET3 PHACTR1

2.99e-03218393C0036572
Diseasevisceral:subcutaneous adipose tissue ratio

SCART1 RFLNA

3.88e-0370392EFO_0004767

Protein segments in the cluster

PeptideGeneStartEntry
SQPDPAMPPGHTRMP

ENKD1

266

Q9H0I2
VSPKPMPELPPMGDN

BPIFB4

401

P59827
APMEPPTSRMFQAPP

ATN1

196

P54259
SPPEMMPTSPQSPRD

DMD

3541

P11532
TPPKMSANPRDPPLM

C1orf94

546

Q6P1W5
TMDDMALPPPPPELL

RAPH1

1196

Q70E73
GPMPPLIREMLENPE

RARG

406

P13631
MEPATAPRPDMAPEL

PTPN9

1

P43378
MPDTPEPIPDYMPLW

IL17RA

306

Q96F46
DEDMPAAGMPPLPQS

MAGEC3

376

Q8TD91
SFPPLPTMPREGRPM

ETV1

196

P50549
LPMLPMVPEEPEDLR

FGF19

166

O95750
REMPPGPEPPTSRKM

DOK3

341

Q7L591
TLEDPAPMTPPPSDM

KIAA1191

36

Q96A73
LPALSEMEPVPMPRD

PHACTR1

191

Q9C0D0
PPRGPLNPDSQRMPM

NCOA6

1056

Q14686
ASVPPSPDKQRMPMP

NCOA6

1086

Q14686
DMMAPRLRPMRPPPP

FCHSD1

661

Q86WN1
MEEPQPPRPPASMAL

GPR135

1

Q8IZ08
ARDVPLEMAEPPDPP

BARX2

251

Q9UMQ3
MLRTMDPSPEAAPPQ

CSF3R

231

Q99062
DMFRMPSRSPLPAPP

ECM2

296

O94769
DDSPGRELPRPEMPM

ENGASE

671

Q8NFI3
RGRPVPMMIPDELAP

EML2

26

O95834
MPAMERLPPERPQPQ

RELL2

216

Q8NC24
PMNKNADSELMPPPP

WRAP53

31

Q9BUR4
MAPSEYMLRPPQPPV

SEC24A

491

O95486
SYLQMPRMPPPLEPI

FGD1

166

P98174
ETRRQPMPDPGLMPL

SIPA1L1

1656

O43166
PMPDPGLMPLPDTAA

SIPA1L1

1661

O43166
APLRPGMPPTMMDPF

SMARCD2

101

Q92925
PMAMEHPPPLPNSRL

TNIP1

576

Q15025
PPESMPKMPPRTPAE

MRPS18B

231

Q9Y676
LPVTPMPREMAFPVP

WDR90

196

Q96KV7
EMPEDSSTPEEMPPP

ZDHHC9

336

Q9Y397
PPPPRSHNMPSDGMV

SS18

96

Q15532
NPPASEMRPRMLPVF

RFLNA

76

Q6ZTI6
VAMPFPPMAPALLRP

SCART1

741

Q4G0T1
PMPRPSPDPMAELEQ

TET3

451

O43151
MLEAMAEPSPEDPPP

PHF23

1

Q9BUL5
AEMVPDLPSPPMEAP

TOM1L2

471

Q6ZVM7
PEESPMSPPPEESPM

KMT2D

576

O14686
EDSPMSPPPEESPMS

KMT2D

631

O14686