Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucosamine-6-phosphate deaminase activity	GNPDA1 GNPDA2	6.14e-06	2	50	2	GO:0004342
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCNKA CLCNKB	3.33e-04	11	50	2	GO:0005247
GeneOntologyMolecularFunction	lipase activity	LIPA PLCD4 LIPK PLBD2	3.93e-04	138	50	4	GO:0016298
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	CLCNKA CLCNKB	8.16e-04	17	50	2	GO:0008308
GeneOntologyBiologicalProcess	glucosamine catabolic process	GNPDA1 GNPDA2	5.76e-06	2	50	2	GO:0006043
GeneOntologyBiologicalProcess	postsynapse organization	PTPRD NRXN1 MYO9A ARHGEF7 ZMYND8 ARHGAP39 SEMA4C	9.89e-06	313	50	7	GO:0099173
GeneOntologyBiologicalProcess	N-acetylglucosamine catabolic process	GNPDA1 GNPDA2	1.73e-05	3	50	2	GO:0006046
GeneOntologyBiologicalProcess	postsynaptic specialization organization	PTPRD NRXN1 MYO9A ZMYND8	2.63e-05	71	50	4	GO:0099084
GeneOntologyBiologicalProcess	regulation of postsynaptic density organization	PTPRD NRXN1 ZMYND8	3.76e-05	27	50	3	GO:1905874
GeneOntologyBiologicalProcess	glucosamine metabolic process	GNPDA1 GNPDA2	8.59e-05	6	50	2	GO:0006041
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	RESF1 PTPRD NRXN1 TRAF3IP1 TRIM9 ARHGEF7 SDCCAG8 ZMYND8 DYNC1H1 SORL1 SEMA4C	1.04e-04	1189	50	11	GO:0044087
GeneOntologyBiologicalProcess	N-acetylneuraminate catabolic process	GNPDA1 GNPDA2	1.20e-04	7	50	2	GO:0019262
GeneOntologyBiologicalProcess	glucosamine-containing compound catabolic process	GNPDA1 GNPDA2	2.05e-04	9	50	2	GO:1901072
GeneOntologyBiologicalProcess	UDP-N-acetylglucosamine biosynthetic process	GNPDA1 GNPDA2	2.05e-04	9	50	2	GO:0006048
GeneOntologyBiologicalProcess	transepithelial chloride transport	CLCNKA CLCNKB	2.56e-04	10	50	2	GO:0030321
GeneOntologyBiologicalProcess	presynaptic membrane assembly	PTPRD NRXN1	2.56e-04	10	50	2	GO:0097105
GeneOntologyBiologicalProcess	lipid catabolic process	LIPA LIPJ PLCD4 LIPK PLBD2 SORL1	3.10e-04	382	50	6	GO:0016042
GeneOntologyBiologicalProcess	postsynaptic density protein 95 clustering	NRXN1 ZMYND8	3.12e-04	11	50	2	GO:0097119
GeneOntologyBiologicalProcess	amino sugar biosynthetic process	GNPDA1 GNPDA2	3.12e-04	11	50	2	GO:0046349
GeneOntologyBiologicalProcess	postsynaptic density organization	PTPRD NRXN1 ZMYND8	3.77e-04	58	50	3	GO:0097106
GeneOntologyBiologicalProcess	N-acetylneuraminate metabolic process	GNPDA1 GNPDA2	4.42e-04	13	50	2	GO:0006054
GeneOntologyBiologicalProcess	presynaptic membrane organization	PTPRD NRXN1	4.42e-04	13	50	2	GO:0097090
GeneOntologyBiologicalProcess	UDP-N-acetylglucosamine metabolic process	GNPDA1 GNPDA2	5.14e-04	14	50	2	GO:0006047
GeneOntologyBiologicalProcess	amino sugar catabolic process	GNPDA1 GNPDA2	5.93e-04	15	50	2	GO:0046348
GeneOntologyBiologicalProcess	morphogenesis of a polarized epithelium	TRAF3IP1 MYO9A JHY	7.40e-04	73	50	3	GO:0001738
GeneOntologyBiologicalProcess	presynapse organization	PTPRD NRXN1 ARHGEF7	7.40e-04	73	50	3	GO:0099172
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex assembly	TRAF3IP1 TRIM9 ARHGEF7 SORL1	8.15e-04	173	50	4	GO:0031333
Domain	Abhydro_lipase	LIPA LIPJ LIPK	3.59e-07	6	50	3	PF04083
Domain	AB_hydrolase_lipase	LIPA LIPJ LIPK	3.59e-07	6	50	3	IPR006693
Domain	Lipase_euk	LIPA LIPJ LIPK	3.59e-07	6	50	3	IPR025483
Domain	Glucosamine6P_isomerase_CS	GNPDA1 GNPDA2	7.02e-06	2	50	2	IPR018321
Domain	Glucosamine6P_isomerase	GNPDA1 GNPDA2	7.02e-06	2	50	2	IPR004547
Domain	Cl_channel-K	CLCNKA CLCNKB	7.02e-06	2	50	2	IPR002250
Domain	GLC_GALNAC_ISOMERASE	GNPDA1 GNPDA2	7.02e-06	2	50	2	PS01161
Domain	Glc/Gal-6P_isomerase	GNPDA1 GNPDA2	4.20e-05	4	50	2	IPR006148
Domain	Glucosamine_iso	GNPDA1 GNPDA2	4.20e-05	4	50	2	PF01182
Domain	LIPASE_SER	LIPA LIPJ LIPK	4.49e-05	26	50	3	PS00120
Domain	VPS10	SORCS2 SORL1	6.99e-05	5	50	2	SM00602
Domain	Sortilin_C	SORCS2 SORL1	6.99e-05	5	50	2	PF15901
Domain	Sortilin-Vps10	SORCS2 SORL1	6.99e-05	5	50	2	PF15902
Domain	VPS10	SORCS2 SORL1	6.99e-05	5	50	2	IPR006581
Domain	Sortilin_N	SORCS2 SORL1	6.99e-05	5	50	2	IPR031778
Domain	Sortilin_C	SORCS2 SORL1	6.99e-05	5	50	2	IPR031777
Domain	Abhydrolase_1	LIPA LIPJ LIPK	7.70e-05	31	50	3	PF00561
Domain	AB_hydrolase_1	LIPA LIPJ LIPK	9.31e-05	33	50	3	IPR000073
Domain	Cl-channel_core	CLCNKA CLCNKB	2.50e-04	9	50	2	IPR014743
Domain	-	CLCNKA CLCNKB	2.50e-04	9	50	2	1.10.3080.10
Domain	Voltage_CLC	CLCNKA CLCNKB	2.50e-04	9	50	2	PF00654
Domain	Cl-channel_volt-gated	CLCNKA CLCNKB	2.50e-04	9	50	2	IPR001807
Domain	Sialidases	SORCS2 SORL1	2.50e-04	9	50	2	IPR011040
Domain	CBS	CLCNKA CLCNKB	8.23e-04	16	50	2	SM00116
Domain	CBS_dom	CLCNKA CLCNKB	1.29e-03	20	50	2	IPR000644
Domain	CBS	CLCNKA CLCNKB	1.29e-03	20	50	2	PF00571
Domain	CBS	CLCNKA CLCNKB	1.29e-03	20	50	2	PS51371
Domain	Chromo_domain	CHD9 CHD1	1.87e-03	24	50	2	IPR023780
Domain	Chromo	CHD9 CHD1	2.19e-03	26	50	2	PF00385
Domain	CHROMO_1	CHD9 CHD1	2.54e-03	28	50	2	PS00598
Domain	CHROMO_2	CHD9 CHD1	2.54e-03	28	50	2	PS50013
Domain	SNF2_N	CHD9 CHD1	3.31e-03	32	50	2	IPR000330
Domain	Chromodomain-like	CHD9 CHD1	3.31e-03	32	50	2	IPR016197
Domain	SNF2_N	CHD9 CHD1	3.31e-03	32	50	2	PF00176
Domain	Chromo/shadow_dom	CHD9 CHD1	3.52e-03	33	50	2	IPR000953
Domain	CHROMO	CHD9 CHD1	3.52e-03	33	50	2	SM00298
Domain	-	LIPA LIPJ LIPK	3.97e-03	119	50	3	3.40.50.1820
Domain	AB_hydrolase	LIPA LIPJ LIPK	3.97e-03	119	50	3	IPR029058
Domain	Myosin_head_motor_dom	MYO1E MYO9A	4.64e-03	38	50	2	IPR001609
Domain	MYOSIN_MOTOR	MYO1E MYO9A	4.64e-03	38	50	2	PS51456
Domain	Myosin_head	MYO1E MYO9A	4.64e-03	38	50	2	PF00063
Domain	MYSc	MYO1E MYO9A	4.64e-03	38	50	2	SM00242
Domain	Quinoprotein_ADH-like_supfam	DMXL2 WDR36	8.87e-03	53	50	2	IPR011047
Domain	fn3	PTPRD TRIM9 SORL1	9.32e-03	162	50	3	PF00041
Pubmed	Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.	CLCNKA CLCNKB	2.03e-06	2	50	2	8544406
Pubmed	The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.	CLCNKA CLCNKB	2.03e-06	2	50	2	27335120
Pubmed	Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study.	GNPDA1 GNPDA2	2.03e-06	2	50	2	12965206
Pubmed	Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.	CLCNKA CLCNKB	2.03e-06	2	50	2	8812470
Pubmed	A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.	CLCNKA CLCNKB	2.03e-06	2	50	2	20805576
Pubmed	Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.	CLCNKA CLCNKB	2.03e-06	2	50	2	25919862
Pubmed	Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin.	GNPDA1 GNPDA2	2.03e-06	2	50	2	12616532
Pubmed	Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.	CLCNKA CLCNKB	2.03e-06	2	50	2	24863058
Pubmed	Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.	CLCNKA CLCNKB	2.03e-06	2	50	2	9916798
Pubmed	Kidney kinetics and chloride ion pumps.	CLCNKA CLCNKB	2.03e-06	2	50	2	9916791
Pubmed	Salt wasting and deafness resulting from mutations in two chloride channels.	CLCNKA CLCNKB	2.03e-06	2	50	2	15044642
Pubmed	Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.	CLCNKA CLCNKB	2.03e-06	2	50	2	38069401
Pubmed	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.	CLCNKA CLCNKB	2.03e-06	2	50	2	8041726
Pubmed	A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.	CLCNKA CLCNKB	2.03e-06	2	50	2	18648499
Pubmed	Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.	CLCNKA CLCNKB	2.03e-06	2	50	2	11014860
Pubmed	Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.	CLCNKA CLCNKB	6.07e-06	3	50	2	26013830
Pubmed	Barttin increases surface expression and changes current properties of ClC-K channels.	CLCNKA CLCNKB	6.07e-06	3	50	2	12111250
Pubmed	Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.	SETBP1 MECOM	6.07e-06	3	50	2	16582916
Pubmed	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.	CLCNKA CLCNKB	6.07e-06	3	50	2	11734858
Pubmed	Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.	CLCNKA CLCNKB	6.07e-06	3	50	2	17510212
Pubmed	Barttin modulates trafficking and function of ClC-K channels.	CLCNKA CLCNKB	6.07e-06	3	50	2	16849430
Pubmed	Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance.	CLCNKA CLCNKB	6.07e-06	3	50	2	18094726
Pubmed	Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor.	CLCNKA CLCNKB	6.07e-06	3	50	2	10982849
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NRXN1 ZMYND8 SORCS2 CHD9	7.70e-06	87	50	4	12465718
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DMXL2 PTPRD NRXN1 TRAF3IP1 ARHGEF7 GIGYF2 ZNFX1 ARHGAP39 DYNC1H1	8.33e-06	963	50	9	28671696
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	VWA3A DMXL2 PTPRD MYO9A KLHL30 ARHGEF7 NBEAL2 ZMYND8 COMMD10 CHD9	9.09e-06	1242	50	10	30973865
Pubmed	Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.	CPA6 NRXN1 SDCCAG8 ARHGAP39	1.05e-05	94	50	4	25201988
Pubmed	Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption.	CLCNKA CLCNKB	1.21e-05	4	50	2	17652939
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DMXL2 PTPRD TRAF3IP1 MYO1E TRIM9 ZMYND8 CHD9 ZNFX1 DYNC1H1 ZNF662	1.22e-05	1285	50	10	35914814
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DMXL2 NRXN1 TRIM9 SETBP1 GIGYF2	1.81e-05	225	50	5	12168954
Pubmed	Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.	GNPDA1 GNPDA2	2.02e-05	5	50	2	26887390
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZNF787 DMXL2 LIPA NRXN1 ARHGEF7 ZMYND8 CHD9 ARHGAP39 DYNC1H1	2.10e-05	1082	50	9	38697112
Pubmed	Independent origins of fetal liver haematopoietic stem and progenitor cells.	COMMD10 MECOM	3.03e-05	6	50	2	36104564
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	DMXL2 NRXN1 ARHGEF7 ARHGAP39 DYNC1H1	3.06e-05	251	50	5	27507650
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GJA3 DMXL2 MYO1E MYO9A TRIM9 SORCS2 ZNFX1 ARHGAP39 DYNC1H1 GOT2	3.08e-05	1431	50	10	37142655
Pubmed	Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration.	COMMD10 GOT2	4.23e-05	7	50	2	34450065
Pubmed	Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development.	PTPRD NRXN1	4.23e-05	7	50	2	29107521
Pubmed	Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency.	CLCNKA CLCNKB	4.23e-05	7	50	2	34499620
Pubmed	Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney.	CLCNKA CLCNKB	4.23e-05	7	50	2	11423561
Pubmed	Analyses of shared genetic factors between asthma and obesity in children.	WDR36 PTPRD GNPDA2	4.34e-05	47	50	3	20816195
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	PTPRD NRXN1	5.64e-05	8	50	2	37591863
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	RESF1 TRAF3IP1 TRIM9 DYNC1H1	6.73e-05	151	50	4	17043677
Pubmed	Changing expression of chloride channels during preimplantation mouse development.	CLCNKA CLCNKB	7.25e-05	9	50	2	23115349
Pubmed	Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription.	COMMD10 CHD1	7.25e-05	9	50	2	25831528
Pubmed	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	ARHGEF7 DYNC1H1	1.10e-04	11	50	2	19448619
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	WDR36 ZMYND8 CHD9 CHD1 DYNC1H1 GOT2	1.13e-04	533	50	6	30554943
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	GNPDA1 MYO1E DYNC1H1 GOT2	1.67e-04	191	50	4	33762435
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO1E MYO9A	1.82e-04	14	50	2	8022818
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYO1E ARHGEF7 MECOM GIGYF2 CHD1 DYNC1H1	2.16e-04	601	50	6	33658012
Pubmed	A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.	PTPRD NRXN1	2.72e-04	17	50	2	22832960
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	WDR36 MYO1E CDKN2AIP MECOM GOT2	2.72e-04	400	50	5	35013556
Pubmed	Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.	PTPRD ZMYND8	3.05e-04	18	50	2	27984743
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	DMXL2 ARHGEF7 COMMD10	4.47e-04	103	50	3	29539633
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	NRXN1 TRAF3IP1 MYO1E SDCCAG8 GIGYF2 DYNC1H1 TCTN2 SORL1	5.50e-04	1321	50	8	27173435
Pubmed	Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.	DMXL2 ARHGEF7	6.95e-04	27	50	2	26442671
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ZNF787 WDR36 MYO1E TRIM9 COMMD10 GIGYF2	7.18e-04	754	50	6	33060197
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	ZNF787 ZMYND8 MECOM CHD9	7.27e-04	282	50	4	23667531
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CDKN2AIP NBEAL2 ZMYND8 GIGYF2 CHD9	7.29e-04	497	50	5	36774506
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	RESF1 NRXN1 ZNFX1	8.80e-04	130	50	3	12421765
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RESF1 CLCNKA ZMYND8 MECOM CHD9 TCTN2 SORL1	1.03e-03	1116	50	7	31753913
Pubmed	Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.	DMXL2 DYNC1H1	1.04e-03	33	50	2	26025364
Pubmed	Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.	DMXL2 SEMA4C	1.17e-03	35	50	2	37758766
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DMXL2 PTPRD MYO9A DYNC1H1	1.19e-03	322	50	4	26514267
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	DMXL2 ARHGEF7 DYNC1H1	1.25e-03	147	50	3	16959763
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	DMXL2 MYO1E CDKN2AIP DYNC1H1	1.34e-03	333	50	4	32665550
Pubmed	Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.	ZMYND8 SALL4	1.38e-03	38	50	2	33283408
Cytoband	10q23.31	LIPJ LIPK	6.38e-04	34	50	2	10q23.31
Cytoband	1p36	CLCNKA CLCNKB	1.22e-03	47	50	2	1p36
Cytoband	Ensembl 112 genes in cytogenetic band chr10q23	LIPA LIPJ LIPK	1.28e-03	195	50	3	chr10q23
Cytoband	Ensembl 112 genes in cytogenetic band chr2q37	TRAF3IP1 KLHL30 GIGYF2	1.95e-03	226	50	3	chr2q37
Cytoband	2q37.3	TRAF3IP1 KLHL30	3.23e-03	77	50	2	2q37.3
GeneFamily	Lipases\|Arylacetamide deacetylase family	LIPA LIPJ LIPK	9.13e-06	22	34	3	464
GeneFamily	Chloride voltage-gated channels	CLCNKA CLCNKB	1.53e-04	10	34	2	302
GeneFamily	Fibronectin type III domain containing	PTPRD TRIM9 SORL1	3.33e-03	160	34	3	555
Coexpression	LAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB	MYO1E MYO9A SDCCAG8 ZMYND8 MECOM	1.76e-05	169	50	5	M39230
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL	NRXN1 TRIM9 ZMYND8 TCTN2 SEMA4C	3.33e-05	193	50	5	M6813
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL	NRXN1 TRIM9 ZMYND8 TCTN2 SEMA4C	3.58e-05	196	50	5	MM667
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB MECOM PLCD4 PTCHD4 SORL1	5.71e-08	183	50	6	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SETBP1 MECOM SALL4 THNSL2 ZNF662	1.03e-06	161	50	5	46b5d80d2d521fb69752aba4c10383e715a32002
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB ZMYND8 SORCS2 MECOM	1.87e-06	182	50	5	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB SORCS2 MECOM SORL1	2.14e-06	187	50	5	52b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A SETBP1 ZMYND8 SORCS2 MECOM	2.25e-06	189	50	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 SORCS2 THNSL2 SORL1	3.20e-05	161	50	4	9f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB MECOM PTCHD4	4.43e-05	175	50	4	787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB MECOM SORL1	4.63e-05	177	50	4	dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKB MECOM PLCD4 SORL1	4.63e-05	177	50	4	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB SORCS2 MECOM	4.94e-05	180	50	4	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA ZMYND8 SORCS2 MECOM	4.94e-05	180	50	4	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB SORCS2 MECOM	4.94e-05	180	50	4	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRD MYO9A PTCHD4 JHY	5.05e-05	181	50	4	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB ZMYND8 MECOM	5.27e-05	183	50	4	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB ZMYND8 MECOM	5.50e-05	185	50	4	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	5'-Adult-Distal_Rectal-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPA6 DMXL2 MYO1E NBEAL2	5.61e-05	186	50	4	4046b701aa29712d9f7c774f8955215122c3c003
ToppCell	5'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPA6 DMXL2 MYO1E NBEAL2	5.61e-05	186	50	4	bd5837033c1ffcbe5dd30195cc4846a2ba351bcd
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PTPRD TRIM9 SETBP1 MECOM	5.61e-05	186	50	4	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	VWA3A PTPRD SETBP1 MECOM	5.73e-05	187	50	4	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	VWA3A PTPRD SORCS2 MECOM	5.73e-05	187	50	4	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB SORCS2 MECOM	5.73e-05	187	50	4	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CPA6 MYO1E ZMYND8 PTCHD4	5.85e-05	188	50	4	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	PTPRD TRIM9 MECOM CHD9	6.10e-05	190	50	4	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM SORL1	6.10e-05	190	50	4	c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM SORL1	6.10e-05	190	50	4	5cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 TRIM9 SORCS2 PLCD4	6.22e-05	191	50	4	fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM SORL1	6.22e-05	191	50	4	297bc79adc5fef211497819b4861b52cd26ac754
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM SORL1	6.22e-05	191	50	4	e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCell	IPF-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	PTPRD SORCS2 MECOM PTCHD4	6.35e-05	192	50	4	356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 TRIM9 SORCS2 PLCD4	6.35e-05	192	50	4	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM SORL1	6.35e-05	192	50	4	61c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM SORL1	6.35e-05	192	50	4	e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GJA3 CLCNKA JHY	6.43e-05	69	50	3	0862e6c8d8af4310b9a1f0879e51ee25115b26b1
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GJA3 CLCNKA JHY	6.43e-05	69	50	3	d2ff9cea216122d697822cdd2eecbce8f557728d
ToppCell	COVID-19_Convalescent-PLT_4\|COVID-19_Convalescent / Disease Group and Platelet Clusters	RESF1 CDKN2AIP ZMYND8 CHD9	6.61e-05	194	50	4	ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E NBEAL2 SORCS2 MECOM	6.61e-05	194	50	4	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E NBEAL2 SORCS2 MECOM	6.61e-05	194	50	4	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRD NRXN1 TRIM9 SORL1	6.74e-05	195	50	4	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DMXL2 LIPA CHD1 SORL1	7.01e-05	197	50	4	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PTPRD SDCCAG8 SORCS2 MECOM	7.15e-05	198	50	4	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DMXL2 RESF1 CHD1 SORL1	7.29e-05	199	50	4	9da8b48ec1c1c105fcbab6ae8f08166e7d5e8a35
ToppCell	CTRL-Myeloid\|CTRL / Disease state, Lineage and Cell class	DMXL2 LIPA SDCCAG8 MYDGF	7.29e-05	199	50	4	70b89a930709fdb91fde6f96106add8455b11618
ToppCell	Kidney-Tubules\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	CLCNKA CLCNKB MECOM SORL1	7.44e-05	200	50	4	0726456906e078244a9cff35aee8c5bce4566fb1
ToppCell	Kidney\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	CLCNKA CLCNKB MECOM SORL1	7.44e-05	200	50	4	1f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Slc17a6.Cbln1_(Entopeduncular_Nucleus_(Ent),_GABA/Glu_co-releasing)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CPA6 GJA3 CLCNKA	8.57e-05	76	50	3	f653a09d6707d9b34db4ef486212aeba5610f47b
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Slc17a6.Cbln1_(Entopeduncular_Nucleus_(Ent),_GABA/Glu_co-releasing)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CPA6 GJA3 CLCNKA	8.57e-05	76	50	3	47deea63d975366a42834c22cc163c4c7142d51d
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2-Slc17a6.Cbln1_(Entopeduncular_Nucleus_(Ent),_GABA/Glu_co-releasing)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CPA6 GJA3 CLCNKA	8.57e-05	76	50	3	079e1af894e670f63d718e16599f20d920643160
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CPA6 CLCNKB JHY	5.09e-04	139	50	3	96e6fed23e7a69f678f85e8e2fe77a7491586b4b
ToppCell	pdx-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PLCD4 ZNFX1 DYNC1H1	5.64e-04	144	50	3	0b94d978262a826c9254145aa98c6c30240243f9
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB MECOM	6.72e-04	153	50	3	0307f10e772021ae68a42690634df458672a6df9
ToppCell	Control-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	CLCNKA CLCNKB SORL1	6.98e-04	155	50	3	4b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TRIM9 JMJD4 PLBD2	7.11e-04	156	50	3	fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKB MECOM PLCD4	7.11e-04	156	50	3	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 RESF1 SORL1	7.24e-04	157	50	3	5098675f64342c41c5ca3551b24962d10c83e64d
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRXN1 MECOM PTCHD4	7.24e-04	157	50	3	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 RESF1 SORL1	7.38e-04	158	50	3	d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 RESF1 SORL1	7.38e-04	158	50	3	ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCell	IPF-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	CLCNKA CLCNKB SORL1	7.38e-04	158	50	3	67adf625a959444762d32268b3b7441f6f8b3b8c
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 DMXL2 SORL1	7.51e-04	159	50	3	a6093b230afdd4d91870d289c6ac91d1856666a3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPA6 MYO1E TRIM9	7.51e-04	159	50	3	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	droplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO9A ZMYND8 ARHGAP39	7.65e-04	160	50	3	a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	RESF1 TRIM9 SORL1	7.79e-04	161	50	3	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	normal-na-Lymphocytic_T-T4_reg-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CPA6 RESF1 ARHGAP39	8.07e-04	163	50	3	43887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CLCNKB SORCS2 MECOM	8.51e-04	166	50	3	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	RESF1 TRAF3IP1 GIGYF2	8.51e-04	166	50	3	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-7\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CLCNKA PLCD4 GOT2	8.66e-04	167	50	3	01c42e555913b17e62846325cc17b3d8f92da1e1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA3 PTPRD MYO1E	8.81e-04	168	50	3	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GJA3 PTPRD MYO1E	8.81e-04	168	50	3	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CLCNKA CLCNKB MECOM	8.96e-04	169	50	3	7d39da562373865876fe16f35649b68da30a0a3a
ToppCell	facs-BAT-Fat-18m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 RESF1 SORL1	8.96e-04	169	50	3	d3e6c75e5eda133fb6535cfe6c6a1026641f26ac
ToppCell	Ciliated_cells-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	VWA3A SALL4 TCTN2	9.12e-04	170	50	3	3d3a03979014df3a05c49be18010c6b94d786707
ToppCell	facs-BAT-Fat-24m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 RESF1 SORL1	9.12e-04	170	50	3	53916d85f0d6c7e5ef3d900d6ead946f75e32567
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPA6 MYO1E TRIM9	9.12e-04	170	50	3	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	facs-BAT-Fat-3m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 RESF1 SORL1	9.12e-04	170	50	3	8fd0a55266066a51266ab616c38c883e2680bcf4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPA6 MYO1E TRIM9	9.12e-04	170	50	3	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	Ionocyte\|World / Class top	NRXN1 CLCNKB PLCD4	9.12e-04	170	50	3	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 DMXL2 SORL1	9.27e-04	171	50	3	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA6 DMXL2 SORL1	9.27e-04	171	50	3	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	Nasal_Brush-Epithelial-Ionocytes\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CLCNKA CLCNKB ZNF662	9.43e-04	172	50	3	dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM	9.43e-04	172	50	3	87a30a219b0a6979abb5fba292a2d8ea946fd849
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GNPDA1 PLCD4 PLBD2	9.43e-04	172	50	3	9befd44bce43eb5dc1fe3d2e44608f442cf74a47
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB MECOM	9.43e-04	172	50	3	5030ac31709cac236bb58f4ef9d545d24690411a
ToppCell	Nasal_Brush-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CLCNKA CLCNKB ZNF662	9.43e-04	172	50	3	04fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA ZMYND8 SORCS2	9.43e-04	172	50	3	1565f38266891c3acf49778838de134c5dee5460
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	NRXN1 MYO1E ARHGAP39	9.59e-04	173	50	3	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	severe_influenza-Neutrophil\|severe_influenza / disease group, cell group and cell class (v2)	RESF1 TRIM9 SORL1	9.59e-04	173	50	3	615e266419b9f06e964eff73cb466f05451ba0dd
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF7 SORCS2 SEMA4C	9.59e-04	173	50	3	fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DMXL2 JMJD4 PLBD2	9.59e-04	173	50	3	efb8072475000888efe088d00e870c56ffad4172
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM9 SETBP1 MECOM	9.75e-04	174	50	3	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DMXL2 JMJD4 PLBD2	9.75e-04	174	50	3	58300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA3 PTPRD MYO1E	9.75e-04	174	50	3	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CLCNKA PLCD4 GOT2	9.91e-04	175	50	3	49211b260bbe3c88354fbd1953dc06f92d3eab09
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCNKA CLCNKB SORL1	1.02e-03	177	50	3	6d89042bda8e244babb68929e84b25edcb545a77
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCNKA CLCNKB SORL1	1.02e-03	177	50	3	daaccf1249dcf816df4caca695a944f53078291a
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCNKA CLCNKB SORL1	1.02e-03	177	50	3	c5a16f984c836dbf7d0faf061677844167ab612a
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCNKA CLCNKB SORL1	1.02e-03	177	50	3	338bdda26796bf4e16072878c070212d1006cf57
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 JMJD4 ARHGAP39	1.04e-03	178	50	3	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA CLCNKB SORCS2	1.04e-03	178	50	3	dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 TRIM9 JHY	1.04e-03	178	50	3	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYO1E SETBP1 MECOM	1.06e-03	179	50	3	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
Drug	tyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA	ARHGEF7 ZMYND8 GIGYF2 CHD9 CHD1 SEMA4C	2.78e-06	185	49	6	1114_DN
Disease	Bartter disease type 4B	CLCNKA CLCNKB	2.81e-06	2	50	2	cv:C4310805
Disease	BARTTER SYNDROME, TYPE 4B	CLCNKA CLCNKB	2.81e-06	2	50	2	C2751312
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	2.81e-06	2	50	2	C4310805
Disease	Bartter disease type 3 (implicated_via_orthology)	CLCNKA CLCNKB	2.81e-06	2	50	2	DOID:0110144 (implicated_via_orthology)
Disease	Bartter disease type 4b (is_implicated_in)	CLCNKA CLCNKB	2.81e-06	2	50	2	DOID:0110146 (is_implicated_in)
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	2.81e-06	2	50	2	613090
Disease	Bartter disease (implicated_via_orthology)	CLCNKA CLCNKB	2.81e-06	2	50	2	DOID:445 (implicated_via_orthology)
Disease	Bartter syndrome	CLCNKA CLCNKB	4.20e-05	6	50	2	cv:C0004775
Disease	Renal dysplasia and retinal aplasia	TRAF3IP1 SDCCAG8	5.88e-05	7	50	2	cv:C0403553
Disease	Senior-Loken syndrome (is_implicated_in)	TRAF3IP1 SDCCAG8	5.88e-05	7	50	2	DOID:0050576 (is_implicated_in)
Disease	blood urea nitrogen measurement	CLCNKB SETBP1 MECOM CHD9 PLCD4 SORL1	1.12e-04	452	50	6	EFO_0004741
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	CLCNKA CLCNKB	1.26e-04	10	50	2	DOID:12387 (implicated_via_orthology)
Disease	Semantic-Pragmatic Disorder	NRXN1 SETBP1	1.53e-04	11	50	2	C0454655
Disease	Auditory Processing Disorder, Central	NRXN1 SETBP1	1.53e-04	11	50	2	C0751257
Disease	Language Delay	NRXN1 SETBP1	1.53e-04	11	50	2	C0023012
Disease	Language Development Disorders	NRXN1 SETBP1	1.53e-04	11	50	2	C0023014
Disease	Speech Delay	NRXN1 SETBP1	1.53e-04	11	50	2	C0241210
Disease	Renal dysplasia and retinal aplasia (disorder)	TRAF3IP1 SDCCAG8	1.84e-04	12	50	2	C0403553
Disease	radiation-induced disorder	PTPRD NRXN1 PLBD2	2.03e-04	67	50	3	EFO_0009565
Disease	unipolar depression, anxiety	PTPRD CDKN2AIP	2.53e-04	14	50	2	EFO_0003761, EFO_0005230
Disease	unipolar depression, mood disorder, response to antidepressant	NDC1 PTPRD	2.53e-04	14	50	2	EFO_0003761, EFO_0004247, GO_0036276
Disease	hemorheological measurement	PTPRD NRXN1	2.91e-04	15	50	2	EFO_0803374
Disease	Multiple congenital anomalies	NRXN1 SETBP1	3.77e-04	17	50	2	C0000772
Disease	Myeloid Leukemia	SETBP1 MECOM	4.23e-04	18	50	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SETBP1 MECOM	4.23e-04	18	50	2	C0023466
Disease	Arthrogryposis	MYO9A DYNC1H1	5.79e-04	21	50	2	C0003886
Disease	Alzheimer disease, gastroesophageal reflux disease	CPA6 TRIM9 PTCHD4 SORL1	6.05e-04	228	50	4	EFO_0003948, MONDO_0004975
Disease	otitis media (implicated_via_orthology)	MECOM SALL4	6.36e-04	22	50	2	DOID:10754 (implicated_via_orthology)
Disease	temperament and character inventory	PTPRD NRXN1	7.58e-04	24	50	2	EFO_0004825
Disease	plasma clusterin measurement	PTPRD THNSL2	8.23e-04	25	50	2	EFO_0007656
Disease	Intellectual Disability	NRXN1 SDCCAG8 SETBP1 DYNC1H1 GOT2	9.43e-04	447	50	5	C3714756
Disease	Polydactyly	TRAF3IP1 SALL4 TCTN2	1.04e-03	117	50	3	C0152427
Disease	colorectal cancer, overall survival	WDR36 SORL1	1.11e-03	29	50	2	EFO_0000638, MONDO_0005575
Disease	asphyxia neonatorum	ZNF787 CDKN2AIP	1.35e-03	32	50	2	EFO_1000824
Disease	mean platelet volume	GNPDA1 MYO1E SDCCAG8 SETBP1 ZMYND8 MECOM CHD9	1.58e-03	1020	50	7	EFO_0004584

Protein segments in the cluster

Peptide	Gene	Start	Entry
NSTWQGTDLMHNHVL	ARHGEF7	731	Q14155
SNNNSILHMWHLHLK	DMXL2	901	Q8TDJ6
SLEEIQNWMHHLNKT	CPA6	141	Q8N4T0
NSRNMIRTHEWTHHQ	CHD1	566	O14646
WEAQQAHFHMKQRSS	ARHGAP39	561	Q9C0H5
NLWQKVQSQHSLHEN	KLHL30	491	Q0D2K2
NWKSNLIRHQMSHDS	MECOM	301	Q03112
NELQMWHSENRQHAE	TRAF3IP1	616	Q8TDR0
AAQMAREQNHHTWDQ	JHY	96	Q6NUN7
NHMWTVSAFQQHPRT	GNPDA1	221	P46926
SVQNMLHWSQLLNST	LIPJ	256	Q5W064
QLQQLISFSMAWANH	CDKN2AIP	71	Q9NXV6
TVGWQLNLQMAHSAQ	COMMD10	136	Q9Y6G5
NQWHNVMISRDTSNL	NRXN1	986	Q9ULB1
MAQTQLQSQARSWHS	CHD9	451	Q3L8U1
QQQDSVWGMNHSTLH	GIGYF2	1226	Q6Y7W6
QVHNLDDTISINHNW	JMJD4	316	Q9H9V9
GVSITWAHHSLMENN	MT-CO3	141	P00414
WAHHSLMENNRNQMI	MT-CO3	146	P00414
NHMWTVSAFQQHPRT	GNPDA2	221	Q8TDQ7
DQQMRQNLFTTWSHH	DYNC1H1	3521	Q14204
NGHHHLLMTEQNWAN	GJA3	316	Q9Y6H8
QWLHQQELSEMKHNL	ZMYND8	971	Q9ULU4
RIQVNMWASHALHSS	SALL4	236	Q9UJQ4
QHVNNWMKHNVADSQ	PTPRD	461	P23468
INHTQMNTALIQWHP	PTPRD	831	P23468
VSLNDSHNQMVVHWA	SORL1	96	Q92673
SHNQMVVHWAGEKSN	SORL1	101	Q92673
HCSWEQQQTMARHLT	PLCD4	386	Q9BRC7
HNLQMSSGVTQNVWL	RESF1	106	Q9HCM1
QTLLDASGNMHNSWI	SDCCAG8	176	Q86SQ7
QQATQHSMALLHWGA	NBEAL2	1791	Q6ZNJ1
WFQTVMSDGHQQTSH	PTCHD4	421	Q6ZW05
THNQAMVHWTGENSS	SORCS2	146	Q96PQ0
NSINWSRVLVQMAHH	THNSL2	221	Q86YJ6
QLQAMHTLQDTSWHN	SEMA4C	296	Q9C0C4
GSTHNWQHITDQIGM	GOT2	366	P00505
QHLDSLFDNHSWALM	CLCNKA	356	P51800
QHLDSLFDNHSWALM	CLCNKB	356	P51801
AQHAAWSDTANNLMN	ZNFX1	1896	Q9P2E3
DNNRSWFMHNNSHTN	TRIM9	621	Q9C026
DLLVAHNTWNNYQHM	PLBD2	256	Q8NHP8
QQKSSSQNHMDWSTN	SETBP1	211	Q9Y6X0
NRMNNVTTLHLWQSA	TCTN2	451	Q96GX1
HEAMQWVTHLQAQGS	VWA3A	1021	A6NCI4
FMWNSDLSQHQRVHT	ZNF662	341	Q6ZS27
EENWTHLQSLFNQSM	WDR36	926	Q8NI36
FSWSSNLMQHQRIHT	ZNF787	131	Q6DD87
QWQMSLGTSEDHQHF	MYDGF	76	Q969H8
AGTSVQNMLHWSQAV	LIPA	286	P38571
TSVQNMLHWAQAVNS	LIPK	286	Q5VXJ0
QMQIGSHEHFNSWNQ	MYO1E	486	Q12965
SNVALDSMHWQNDSV	MYO9A	1841	B2RTY4
WISTAMNLHIDEQVH	NDC1	241	Q9BTX1