Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	complement component C3b binding	CFH CFHR1 CR1	2.82e-06	12	48	3	GO:0001851
GeneOntologyMolecularFunction	opsonin binding	CFH CFHR1 CR1	2.89e-05	25	48	3	GO:0001846
GeneOntologyMolecularFunction	complement binding	CFH CFHR1 CR1	6.16e-05	32	48	3	GO:0001848
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBN1 FBN2	3.68e-04	12	48	2	GO:0030023
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBN1 FBN2	5.06e-04	14	48	2	GO:0097493
GeneOntologyMolecularFunction	heparin binding	CFH CCN6 FBN1 ADAMTS1	1.16e-03	192	48	4	GO:0008201
GeneOntologyBiologicalProcess	complement activation	CFH CFHR1 C4BPA CR1	1.94e-05	70	47	4	GO:0006956
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN1 FBN2	3.04e-05	4	47	2	GO:0035583
GeneOntologyBiologicalProcess	regulation of complement activation	CFH C4BPA CR1	3.12e-05	27	47	3	GO:0030449
GeneOntologyBiologicalProcess	activation of membrane attack complex	CFH CR1	7.58e-05	6	47	2	GO:0001905
GeneOntologyBiologicalProcess	regulation of complement activation, alternative pathway	CFH CR1	1.06e-04	7	47	2	GO:0030451
GeneOntologyBiologicalProcess	maintenance of protein location in extracellular region	FBN1 FBN2	1.41e-04	8	47	2	GO:0071694
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	C4BPA CR1	1.41e-04	8	47	2	GO:0045959
GeneOntologyBiologicalProcess	immune complex clearance	CFH CR1	1.81e-04	9	47	2	GO:0002434
GeneOntologyBiologicalProcess	regulation of complement activation, classical pathway	C4BPA CR1	2.26e-04	10	47	2	GO:0030450
GeneOntologyBiologicalProcess	sequestering of extracellular ligand from receptor	FBN1 FBN2	2.76e-04	11	47	2	GO:0035581
GeneOntologyBiologicalProcess	negative regulation of humoral immune response mediated by circulating immunoglobulin	C4BPA CR1	3.31e-04	12	47	2	GO:0002924
GeneOntologyBiologicalProcess	regulation of humoral immune response	CFH C4BPA CR1	3.46e-04	60	47	3	GO:0002920
GeneOntologyBiologicalProcess	regulation of complement-dependent cytotoxicity	CFH CR1	3.90e-04	13	47	2	GO:1903659
GeneOntologyBiologicalProcess	extracellular regulation of signal transduction	FBN1 FBN2	3.90e-04	13	47	2	GO:1900115
GeneOntologyBiologicalProcess	extracellular negative regulation of signal transduction	FBN1 FBN2	3.90e-04	13	47	2	GO:1900116
GeneOntologyBiologicalProcess	negative regulation of complement activation	C4BPA CR1	4.54e-04	14	47	2	GO:0045916
GeneOntologyBiologicalProcess	negative regulation of immunoglobulin mediated immune response	C4BPA CR1	5.98e-04	16	47	2	GO:0002890
GeneOntologyBiologicalProcess	negative regulation of B cell mediated immunity	C4BPA CR1	5.98e-04	16	47	2	GO:0002713
GeneOntologyBiologicalProcess	complement-dependent cytotoxicity	CFH CR1	5.98e-04	16	47	2	GO:0097278
GeneOntologyCellularComponent	extracellular matrix	CCN6 ADAMTSL1 FBN1 FBN2 ADAMTS1 MUC5B ADAMTSL3 MUC5AC F12	1.57e-05	656	48	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	CCN6 ADAMTSL1 FBN1 FBN2 ADAMTS1 MUC5B ADAMTSL3 MUC5AC F12	1.61e-05	658	48	9	GO:0030312
GeneOntologyCellularComponent	microfibril	FBN1 FBN2	3.96e-04	13	48	2	GO:0001527
HumanPheno	Abnormal upper to lower segment ratio	FBN1 FBN2	2.10e-05	3	14	2	HP:0012772
HumanPheno	Choroidal neovascularization	CFH CFHR1 FBN2	2.83e-05	23	14	3	HP:0011506
HumanPheno	Decreased circulating complement factor H concentration	CFH CFHR1	4.20e-05	4	14	2	HP:0005369
HumanPheno	Abnormal morphology of the choroidal vasculature	CFH CFHR1 FBN2	5.20e-05	28	14	3	HP:0025568
HumanPheno	Decreased circulating complement factor I concentration	CFH CFHR1	6.98e-05	5	14	2	HP:0005356
HumanPheno	Decreased circulating complement factor B concentration	CFH CFHR1	6.98e-05	5	14	2	HP:0005416
HumanPheno	Crumpled ear	FBN1 FBN2	1.05e-04	6	14	2	HP:0009901
HumanPheno	Macular hemorrhage	CFH CFHR1	1.46e-04	7	14	2	HP:0025574
HumanPheno	Macular drusen	CFH CFHR1	1.95e-04	8	14	2	HP:0030499
HumanPheno	Reticulocytosis	CFH CFHR1 CUBN	2.50e-04	47	14	3	HP:0001923
Domain	Sushi	CFH CFHR1 C4BPA CSMD2 CR1 CSMD3	3.40e-09	52	47	6	PF00084
Domain	CCP	CFH CFHR1 C4BPA CSMD2 CR1 CSMD3	4.30e-09	54	47	6	SM00032
Domain	SUSHI	CFH CFHR1 C4BPA CSMD2 CR1 CSMD3	5.39e-09	56	47	6	PS50923
Domain	Sushi_SCR_CCP_dom	CFH CFHR1 C4BPA CSMD2 CR1 CSMD3	6.01e-09	57	47	6	IPR000436
Domain	Glyco_hormone_CN	CCN6 MUC5B MUC5AC	6.65e-06	15	47	3	IPR006208
Domain	Cys_knot	CCN6 MUC5B MUC5AC	6.65e-06	15	47	3	PF00007
Domain	CUB	SCUBE1 CUBN CSMD2 CSMD3	6.86e-06	49	47	4	PF00431
Domain	CUB	SCUBE1 CUBN CSMD2 CSMD3	7.45e-06	50	47	4	SM00042
Domain	-	SCUBE1 CUBN CSMD2 CSMD3	8.72e-06	52	47	4	2.60.120.290
Domain	CUB	SCUBE1 CUBN CSMD2 CSMD3	9.42e-06	53	47	4	PS01180
Domain	CTCK_1	CCN6 MUC5B MUC5AC	1.19e-05	18	47	3	PS01185
Domain	CUB_dom	SCUBE1 CUBN CSMD2 CSMD3	1.26e-05	57	47	4	IPR000859
Domain	EGF_CA	SCUBE1 FBN1 FBN2 CUBN F12	1.35e-05	122	47	5	SM00179
Domain	EGF-like_Ca-bd_dom	SCUBE1 FBN1 FBN2 CUBN F12	1.46e-05	124	47	5	IPR001881
Domain	FBN	FBN1 FBN2	1.86e-05	3	47	2	IPR011398
Domain	TSP_1	CCN6 ADAMTSL1 ADAMTS1 ADAMTSL3	1.88e-05	63	47	4	PF00090
Domain	TSP1	CCN6 ADAMTSL1 ADAMTS1 ADAMTSL3	2.13e-05	65	47	4	SM00209
Domain	TSP1_rpt	CCN6 ADAMTSL1 ADAMTS1 ADAMTSL3	2.13e-05	65	47	4	IPR000884
Domain	TSP1	CCN6 ADAMTSL1 ADAMTS1 ADAMTSL3	2.13e-05	65	47	4	PS50092
Domain	CT	CCN6 MUC5B MUC5AC	2.22e-05	22	47	3	SM00041
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL1 ADAMTS1 ADAMTSL3	2.91e-05	24	47	3	IPR013273
Domain	Cys_knot_C	CCN6 MUC5B MUC5AC	3.30e-05	25	47	3	IPR006207
Domain	CTCK_2	CCN6 MUC5B MUC5AC	3.30e-05	25	47	3	PS01225
Domain	cEGF	SCUBE1 FBN1 FBN2	3.73e-05	26	47	3	IPR026823
Domain	cEGF	SCUBE1 FBN1 FBN2	3.73e-05	26	47	3	PF12662
Domain	Growth_fac_rcpt_	CCN6 SCUBE1 FBN1 FBN2 CUBN	4.41e-05	156	47	5	IPR009030
Domain	EGF_CA	SCUBE1 FBN1 FBN2 CUBN	6.43e-05	86	47	4	PF07645
Domain	WxxW_domain	MUC5B MUC5AC	9.24e-05	6	47	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	9.24e-05	6	47	2	PF13330
Domain	EGF_Ca-bd_CS	SCUBE1 FBN1 FBN2 CUBN	1.03e-04	97	47	4	IPR018097
Domain	EGF_CA	SCUBE1 FBN1 FBN2 CUBN	1.11e-04	99	47	4	PS01187
Domain	ASX_HYDROXYL	SCUBE1 FBN1 FBN2 CUBN	1.16e-04	100	47	4	PS00010
Domain	TB	FBN1 FBN2	1.29e-04	7	47	2	PF00683
Domain	EGF-type_Asp/Asn_hydroxyl_site	SCUBE1 FBN1 FBN2 CUBN	1.45e-04	106	47	4	IPR000152
Domain	-	FBN1 FBN2	1.72e-04	8	47	2	3.90.290.10
Domain	TB	FBN1 FBN2	2.21e-04	9	47	2	PS51364
Domain	TB_dom	FBN1 FBN2	2.21e-04	9	47	2	IPR017878
Domain	EGF_3	SCUBE1 FBN1 FBN2 CUBN F12	3.01e-04	235	47	5	PS50026
Domain	EGF	SCUBE1 FBN1 FBN2 CUBN F12	3.01e-04	235	47	5	SM00181
Domain	EGF-like_dom	SCUBE1 FBN1 FBN2 CUBN F12	3.93e-04	249	47	5	IPR000742
Domain	EGF_3	SCUBE1 CUBN	4.03e-04	12	47	2	PF12947
Domain	TIL	MUC5B MUC5AC	4.03e-04	12	47	2	PF01826
Domain	EGF_dom	SCUBE1 CUBN	4.03e-04	12	47	2	IPR024731
Domain	C8	MUC5B MUC5AC	4.03e-04	12	47	2	PF08742
Domain	EGF_1	SCUBE1 FBN1 FBN2 CUBN F12	4.38e-04	255	47	5	PS00022
Domain	Unchr_dom_Cys-rich	MUC5B MUC5AC	4.75e-04	13	47	2	IPR014853
Domain	C8	MUC5B MUC5AC	4.75e-04	13	47	2	SM00832
Domain	EGF-like_CS	SCUBE1 FBN1 FBN2 CUBN F12	4.87e-04	261	47	5	IPR013032
Domain	EGF_2	SCUBE1 FBN1 FBN2 CUBN F12	5.22e-04	265	47	5	PS01186
Domain	PLAC	ADAMTSL1 ADAMTSL3	5.53e-04	14	47	2	PF08686
Domain	TIL_dom	MUC5B MUC5AC	5.53e-04	14	47	2	IPR002919
Domain	VWD	MUC5B MUC5AC	7.27e-04	16	47	2	SM00216
Domain	VWF_type-D	MUC5B MUC5AC	7.27e-04	16	47	2	IPR001846
Domain	VWFD	MUC5B MUC5AC	7.27e-04	16	47	2	PS51233
Domain	VWD	MUC5B MUC5AC	7.27e-04	16	47	2	PF00094
Domain	VWC_out	MUC5B MUC5AC	1.03e-03	19	47	2	SM00215
Domain	PLAC	ADAMTSL1 ADAMTSL3	1.03e-03	19	47	2	PS50900
Domain	PLAC	ADAMTSL1 ADAMTSL3	1.03e-03	19	47	2	IPR010909
Domain	VWC	MUC5B MUC5AC	2.25e-03	28	47	2	PF00093
Domain	VWFC_1	MUC5B MUC5AC	3.70e-03	36	47	2	PS01208
Domain	VWC	MUC5B MUC5AC	4.11e-03	38	47	2	SM00214
Domain	Bromodomain	KAT2B ZMYND8	4.11e-03	38	47	2	PF00439
Domain	VWFC_2	MUC5B MUC5AC	4.11e-03	38	47	2	PS50184
Domain	BROMODOMAIN_2	KAT2B ZMYND8	4.77e-03	41	47	2	PS50014
Domain	BROMO	KAT2B ZMYND8	5.01e-03	42	47	2	SM00297
Domain	Bromodomain	KAT2B ZMYND8	5.01e-03	42	47	2	IPR001487
Domain	-	KAT2B ZMYND8	5.01e-03	42	47	2	1.20.920.10
Domain	VWF_dom	MUC5B MUC5AC	5.01e-03	42	47	2	IPR001007
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTSL1 ADAMTS1 MUC5B ADAMTSL3 MUC5AC	7.55e-07	68	36	5	M27303
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTSL1 ADAMTS1 MUC5B ADAMTSL3 MUC5AC	7.85e-06	109	36	5	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTSL1 ADAMTS1 MUC5B ADAMTSL3 MUC5AC	8.58e-06	111	36	5	M27416
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	CFH C4BPA CR1 F12	2.75e-05	69	36	4	M16894
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTSL1 ADAMTS1 MUC5B ADAMTSL3 MUC5AC	2.93e-05	143	36	5	M27275
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTSL1 ADAMTS1 MUC5B CUBN ADAMTSL3 MUC5AC	3.65e-05	250	36	6	M27554
Pathway	KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN	CFH CR1	6.31e-05	5	36	2	M47875
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR	CFH CFHR1	9.45e-05	6	36	2	M47880
Pathway	WP_COMPLEMENT_SYSTEM	CFH C4BPA CR1 F12	1.01e-04	96	36	4	M39581
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTSL1 ADAMTS1 ADAMTSL3	1.31e-04	39	36	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTSL1 ADAMTS1 ADAMTSL3	1.31e-04	39	36	3	MM15165
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH CFHR1 C4BPA CR1	2.02e-04	115	36	4	M19752
Pathway	WP_COMPLEMENT_AND_COAGULATION_CASCADES	CFH CR1 F12	4.29e-04	58	36	3	M39649
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	SCUBE1 FBN1 FBN2 ADAMTS1	4.29e-04	140	36	4	M587
Pathway	WP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES	CFH CR1 F12	4.51e-04	59	36	3	M48343
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC5B MUC5AC	7.44e-04	16	36	2	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC5B MUC5AC	8.42e-04	17	36	2	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC5AC	1.29e-03	21	36	2	MM15706
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC5AC	1.55e-03	23	36	2	M556
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	FBN1 FBN2	1.83e-03	25	36	2	M39713
Pathway	REACTOME_DECTIN_2_FAMILY	MUC5B MUC5AC	1.98e-03	26	36	2	M27483
Pathway	WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY	CFH C4BPA CR1	2.46e-03	106	36	3	M42535
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 FBN2	3.00e-03	32	36	2	MM14854
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	SCUBE1 FBN1 FBN2	3.03e-03	114	36	3	MM14571
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	CCN6 ADAMTSL1 ADAMTS1 CUBN ADAMTSL3	7.21e-08	75	49	5	20637190
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	CFH CFHR1 C4BPA CR1	1.06e-07	31	49	4	19344414
Pubmed	Genetic organization of complement receptor-related genes in the mouse.	CFH C4BPA CR1	1.46e-07	8	49	3	2564419
Pubmed	Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.	CFH CFHR1 C4BPA	2.19e-07	9	49	3	20059470
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	1.94e-06	2	49	2	7513696
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	1.94e-06	2	49	2	12399449
Pubmed	Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces.	CFH CFHR1	1.94e-06	2	49	2	33732239
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	1.94e-06	2	49	2	21851253
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	1.94e-06	2	49	2	12429739
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	1.94e-06	2	49	2	34058148
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	1.94e-06	2	49	2	37146737
Pubmed	Contact activation-induced complex formation between complement factor H and coagulation factor XIIa.	CFH F12	1.94e-06	2	49	2	31984663
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	1.94e-06	2	49	2	14988081
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	1.94e-06	2	49	2	30044367
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	1.94e-06	2	49	2	21440062
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	1.94e-06	2	49	2	15131124
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	1.94e-06	2	49	2	15563276
Pubmed	NC4 Domain of cartilage-specific collagen IX inhibits complement directly due to attenuation of membrane attack formation and indirectly through binding and enhancing activity of complement inhibitors C4B-binding protein and factor H.	CFH C4BPA	1.94e-06	2	49	2	21659506
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	1.94e-06	2	49	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	1.94e-06	2	49	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	1.94e-06	2	49	2	22391959
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	1.94e-06	2	49	2	14718370
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	1.94e-06	2	49	2	35776514
Pubmed	Interaction between complement regulators and Streptococcus pyogenes: binding of C4b-binding protein and factor H/factor H-like protein 1 to M18 strains involves two different cell surface molecules.	CFH CFHR1	1.94e-06	2	49	2	15557185
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	1.94e-06	2	49	2	12524050
Pubmed	Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome.	CFH CFHR1	1.94e-06	2	49	2	21677636
Pubmed	Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations.	CFH CFHR1	1.94e-06	2	49	2	22136554
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	1.94e-06	2	49	2	20404337
Pubmed	Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.	CFH CFHR1	1.94e-06	2	49	2	18824548
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	1.94e-06	2	49	2	24327612
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	1.94e-06	2	49	2	8791520
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	1.94e-06	2	49	2	21653907
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	1.94e-06	2	49	2	36427316
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	1.94e-06	2	49	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	1.94e-06	2	49	2	35419902
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	1.94e-06	2	49	2	8307578
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	1.94e-06	2	49	2	10504303
Pubmed	Anti-factor H autoantibody-associated hemolytic uremic syndrome: review of literature of the autoimmune form of HUS.	CFH CFHR1	1.94e-06	2	49	2	20865640
Pubmed	A synthetic protein as efficient multitarget regulator against complement over-activation.	CFH CFHR1	1.94e-06	2	49	2	35194132
Pubmed	Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome.	CFH CFHR1	1.94e-06	2	49	2	23243267
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	1.94e-06	2	49	2	28607090
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	1.94e-06	2	49	2	7744963
Pubmed	Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule.	CFH CFHR1	1.94e-06	2	49	2	1826708
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	1.94e-06	2	49	2	26408953
Pubmed	Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome.	CFH CFHR1	1.94e-06	2	49	2	22894814
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	1.94e-06	2	49	2	18006876
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	1.94e-06	2	49	2	23272068
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	1.94e-06	2	49	2	31030254
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	1.94e-06	2	49	2	27729120
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	1.94e-06	2	49	2	23527003
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	1.94e-06	2	49	2	24833718
Pubmed	Human complement factor H and factor H-like protein 1 are expressed in human retinal pigment epithelial cells.	CFH CFHR1	1.94e-06	2	49	2	24280833
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	1.94e-06	2	49	2	16540890
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	1.94e-06	2	49	2	36111525
Pubmed	A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome.	CFH CFHR1	1.94e-06	2	49	2	23880784
Pubmed	Binding of the human complement regulators CFHR1 and factor H by streptococcal collagen-like protein 1 (Scl1) via their conserved C termini allows control of the complement cascade at multiple levels.	CFH CFHR1	1.94e-06	2	49	2	20855886
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	1.94e-06	2	49	2	27845589
Pubmed	Complement factor H: a biomarker for progression of cutaneous squamous cell carcinoma.	CFH CFHR1	1.94e-06	2	49	2	23938460
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	1.94e-06	2	49	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	1.94e-06	2	49	2	20529844
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	1.94e-06	2	49	2	25524144
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	1.94e-06	2	49	2	27435107
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	1.94e-06	2	49	2	26871672
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	1.94e-06	2	49	2	23133647
Pubmed	Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.	CFH CFHR1	1.94e-06	2	49	2	23873044
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	1.94e-06	2	49	2	16407178
Pubmed	CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome.	CFH CFHR1	1.94e-06	2	49	2	36755127
Pubmed	Assignment of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes.	CFH CR1	1.94e-06	2	49	2	2977721
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	1.94e-06	2	49	2	1852206
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	1.94e-06	2	49	2	32348677
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	1.94e-06	2	49	2	11587997
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	1.94e-06	2	49	2	10359653
Pubmed	The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease.	CFH CFHR1	1.94e-06	2	49	2	25659429
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	1.94e-06	2	49	2	24332705
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	1.94e-06	2	49	2	34656442
Pubmed	Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent.	CFH CFHR1	5.83e-06	3	49	2	20581873
Pubmed	Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome.	CFH CFHR1	5.83e-06	3	49	2	26163426
Pubmed	Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.	CFH CFHR1	5.83e-06	3	49	2	10781834
Pubmed	Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.	FBN1 FBN2	5.83e-06	3	49	2	10825173
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	5.83e-06	3	49	2	27776277
Pubmed	Dihydrolipoamide dehydrogenase of Pseudomonas aeruginosa is a surface-exposed immune evasion protein that binds three members of the factor H family and plasminogen.	CFH CFHR1	5.83e-06	3	49	2	23071278
Pubmed	Association assessment of copy number polymorphism and risk of age-related macular degeneration.	CFH CFHR1	5.83e-06	3	49	2	21856016
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD3	5.83e-06	3	49	2	12906867
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	5.83e-06	3	49	2	29286856
Pubmed	A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.	CFH CR1	5.83e-06	3	49	2	3782802
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	5.83e-06	3	49	2	36675209
Pubmed	Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy.	CFH CFHR1	5.83e-06	3	49	2	25205734
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	FBN1 FBN2	5.83e-06	3	49	2	30201140
Pubmed	Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency.	CFH CFHR1	5.83e-06	3	49	2	18006700
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	5.83e-06	3	49	2	29802623
Pubmed	Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.	CFH CR1	5.83e-06	3	49	2	20702729
Pubmed	Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.	CFH CFHR1	5.83e-06	3	49	2	19531976
Pubmed	Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35).	CFH CR1	5.83e-06	3	49	2	9988761
Pubmed	Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity.	CFH CFHR1	5.83e-06	3	49	2	19308255
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	5.83e-06	3	49	2	34158522
Pubmed	Evaluation of CFH Y402H polymorphism and CFHR3/CFHR1 deletion in age-related macular degeneration patients from Brazil.	CFH CFHR1	5.83e-06	3	49	2	26942649
Pubmed	An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD).	CFH CFHR1	5.83e-06	3	49	2	20843825
Pubmed	Associations of CFH polymorphisms and CFHR1-CFHR3 deletion with blood pressure and hypertension in Chinese population.	CFH CFHR1	5.83e-06	3	49	2	22848687
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	5.83e-06	3	49	2	29604272
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	5.83e-06	3	49	2	19596978
Cytoband	1q32	CFH CFHR1 C4BPA CR1	2.34e-07	49	49	4	1q32
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH CFHR1 C4BPA CSMD2 CR1 CSMD3	6.37e-10	57	32	6	1179
GeneFamily	Complement system\|Sushi domain containing	CFH CFHR1 CR1	3.46e-05	36	32	3	492
GeneFamily	ADAMTS like	ADAMTSL1 ADAMTSL3	6.34e-05	7	32	2	947
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	6.24e-04	21	32	2	648
Coexpression	NABA_MATRISOME	CCN6 SCUBE1 ADAMTSL1 FBN1 FBN2 ADAMTS1 SPOCK1 MUC5B C4BPA ADAMTSL3 MUC5AC F12	2.43e-07	1008	49	12	MM17056
Coexpression	NABA_MATRISOME	CCN6 SCUBE1 ADAMTSL1 FBN1 FBN2 ADAMTS1 SPOCK1 MUC5B ADAMTSL3 MUC5AC F12	2.33e-06	1026	49	11	M5889
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL	CFH FBN2 ADAMTS1 SPOCK1 CUBN NPLOC4	5.06e-05	355	49	6	M45758
Coexpression	CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3	KAT2B FBN2 STARD4 ZMYND8 HIC2 C4BPA TMC5 MUC5AC	5.51e-05	726	49	8	M4210
CoexpressionAtlas	BM Top 100 - stomach pyloric	CDCA7 FAM3B TMC5 MUC5AC	1.78e-05	69	48	4	BM Top 100 - stomach pyloric
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	CFH ADAMTSL1 FBN1 ADAMTS1 SPOCK1 ADAMTSL3	5.92e-08	188	49	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH SCUBE1 FBN1 ADAMTS1 ADAMTSL3 CSMD3	8.29e-08	199	49	6	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH ADAMTSL1 FBN2 ADAMTS1 CSMD3	1.36e-06	174	49	5	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH ADAMTSL1 MUC5B TMC5 MUC5AC	1.48e-06	177	49	5	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH ADAMTSL1 MUC5B TMC5 MUC5AC	1.48e-06	177	49	5	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	FAM180B FBN1 FBN2 SPOCK1 ADAMTSL3	1.65e-06	181	49	5	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFH ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	1.79e-06	184	49	5	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	CFH ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	1.83e-06	185	49	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	21-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	CFH ADAMTSL1 MUC5B TMC5 MUC5AC	1.88e-06	186	49	5	f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTSL1 FBN1 FBN2 ADAMTSL3	1.93e-06	187	49	5	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTSL1 FBN1 FBN2 ADAMTSL3	1.93e-06	187	49	5	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTSL1 FBN1 FBN2 ADAMTSL3	1.93e-06	187	49	5	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	CFH CCN6 FBN1 FBN2 ADAMTSL3	1.98e-06	188	49	5	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MST1R ADAMTSL1 FBN1 FBN2 ADAMTSL3	2.20e-06	192	49	5	ac1477433704573f95111eee6263b93668d2845e
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MST1R ADAMTSL1 FBN1 FBN2 ADAMTSL3	2.20e-06	192	49	5	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	CFH ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	2.20e-06	192	49	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MST1R ADAMTSL1 FBN1 FBN2 ADAMTSL3	2.20e-06	192	49	5	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CCN6 SPOCK1 TJP1 CR1	2.31e-06	194	49	5	43eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAMTSL1 FBN1 FBN2 ZDHHC19 CSMD2	2.37e-06	195	49	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAMTSL1 FBN1 FBN2 ZDHHC19 CSMD2	2.37e-06	195	49	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCN6 SCUBE1 FBN1 FBN2 CSMD3	2.49e-06	197	49	5	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDCA7 FAM3B MUC5B TMC5 F12	2.49e-06	197	49	5	9ae6d987e65972e1fb21aa407788d5e3ff41ad64
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDCA7 FAM3B MUC5B TMC5 F12	2.49e-06	197	49	5	c0250509836f1be04f5e54386191d7bb1e1da652
ToppCell	droplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SCUBE1 FBN1 ADAMTS1 ADAMTSL3	2.56e-06	198	49	5	d4f74320ea6c1a7e568ee5bc48bb66cb45e1004d
ToppCell	COPD-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	CFH FAM180B FBN1 ADAMTS1 ADAMTSL3	2.56e-06	198	49	5	2f13c0b3372af53d1bd85f9546f315c878580a71
ToppCell	BL-critical-LOC-Epithelial-Secretory_LYPD2\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFH FAM3B MUC5B TMC5 MUC5AC	2.56e-06	198	49	5	484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH FBN1 ADAMTS1 DISP2 MUC5B	2.62e-06	199	49	5	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH ADAMTSL1 ADAMTS1 TJP1 DISP2	2.62e-06	199	49	5	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	2.62e-06	199	49	5	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	2.69e-06	200	49	5	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH FBN1 MUC5B CUBN CSMD2	2.69e-06	200	49	5	29054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	2.69e-06	200	49	5	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	CFH FBN1 ADAMTS1 SPOCK1 ADAMTSL3	2.69e-06	200	49	5	ee3d06865a6300e1279edf6664320b71647f5efb
ToppCell	distal-1-mesenchymal-Adventitial_Fibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH FBN1 ADAMTS1 SPOCK1 ADAMTSL3	2.69e-06	200	49	5	738060ed65fa5473fdb39e686f7cdecc059ed92c
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	2.69e-06	200	49	5	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH FAM180B FBN1 ADAMTS1 SPOCK1	2.69e-06	200	49	5	687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PPM1E ADAMTSL3 CSMD3	2.01e-05	146	49	4	ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PPM1E FAM3B ADAMTSL3 CSMD3	2.36e-05	152	49	4	655d47efe0608d729801f1f01668e84c1bc0675f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th-Slc17a6-Lpl_(VTA_(ventral_VTA))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MST1R ZDHHC19 F12	2.74e-05	53	49	3	605cd3214c1c17a11b69ca65b44c4a3a322f3fbb
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th-Slc17a6-Lpl_(VTA_(ventral_VTA))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MST1R ZDHHC19 F12	2.74e-05	53	49	3	e7f69a8b4dab2d63da84b7aaa7e192c8e19a06ad
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-7\|TCGA-Cervix / Sample_Type by Project: Shred V9	MUC5B C4BPA TMC5 MUC5AC	2.81e-05	159	49	4	75a82bbabd97b168dbf1c3f43a9bdad48ce18c78
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH ADAMTSL1 MUC5B TMC5	2.95e-05	161	49	4	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	15-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	CCN6 SCUBE1 PNMT ADAMTS1	3.25e-05	165	49	4	531804467601e1ee1f771cffa21501f6d464ae10
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PPM1E ADAMTSL3 CSMD3	3.25e-05	165	49	4	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MST1R CFHR1 ADAMTSL1 FAM3B	3.25e-05	165	49	4	4297588f809e8a8275ab1a6ed99daac7ad93bd61
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFH ADAMTSL1 MUC5B MUC5AC	3.41e-05	167	49	4	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN TMC5 CSMD2 CSMD3	3.41e-05	167	49	4	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SPOCK1 TJP1 CR1	3.49e-05	168	49	4	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFH CFHR1 FBN1 ADAMTS1	3.49e-05	168	49	4	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	CFH CFHR1 FBN1 ADAMTS1	3.49e-05	168	49	4	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B C4BPA TMC5 MUC5AC	3.57e-05	169	49	4	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH FBN1 FBN2 ADAMTS1	3.57e-05	169	49	4	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	MUC5B C4BPA TMC5 MUC5AC	3.73e-05	171	49	4	1af575809b3334bfaa019ff26c56e6cb03c82ee8
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH ADAMTSL1 FBN1 SPOCK1	3.82e-05	172	49	4	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH MUC5B TMC5 MUC5AC	3.91e-05	173	49	4	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFH PPM1E MUC5B MUC5AC	4.09e-05	175	49	4	4bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFH PPM1E MUC5B MUC5AC	4.09e-05	175	49	4	af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PPM1E ADAMTSL3 CSMD3	4.18e-05	176	49	4	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ADAMTSL1 FBN1 PRAF2 ADAMTSL3	4.18e-05	176	49	4	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFH FBN1 MUC5B MUC5AC	4.27e-05	177	49	4	709235694cc711b9b79690e23c94577b2ae06811
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFH FBN1 MUC5B MUC5AC	4.27e-05	177	49	4	7f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell	(5)_Glands_mucous\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MUC5B C4BPA TMC5 MUC5AC	4.37e-05	178	49	4	f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PPM1E ADAMTSL3 CSMD3	4.37e-05	178	49	4	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SPOCK1 TJP1 CR1	4.46e-05	179	49	4	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 PPM1E ADAMTSL3 CSMD3	4.56e-05	180	49	4	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	(5)_Epithelial_cells-(5)_Glands_mucous\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MUC5B C4BPA TMC5 MUC5AC	4.56e-05	180	49	4	a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell	Control-Epithelial-Goblet\|Control / Disease state, Lineage and Cell class	CFH MUC5B TMC5 MUC5AC	4.56e-05	180	49	4	5293d23b8b8ea587239ffde561b70bad01632521
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH SCUBE1 FBN1 ADAMTS1	4.66e-05	181	49	4	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH CFHR1 CCN6 C4BPA	4.66e-05	181	49	4	65eaa9bc1022bcf0c5f0f92c07a2cbbf11f9b59c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(PRG4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH CFHR1 CCN6 C4BPA	4.66e-05	181	49	4	eaac7d58117eddfff06b25521efc431c1351d592
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 PPM1E ADAMTSL3 CSMD3	4.76e-05	182	49	4	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFH MUC5B TMC5 MUC5AC	4.76e-05	182	49	4	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH FAM180B FBN1 SPOCK1	4.76e-05	182	49	4	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MST1R CCN6 TMC5	4.83e-05	64	49	3	0f13fbeda23ab9df3488cfae98cb6cd7a3c1b332
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A15 FAM3B MUC5B MUC5AC	4.86e-05	183	49	4	514b72a1ae55656934839800513385e19bc240e2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SPOCK1 TJP1 CR1	4.86e-05	183	49	4	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SPOCK1 TJP1 CR1	4.86e-05	183	49	4	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	C4BPA ZDHHC19 CR1 CSMD3	4.97e-05	184	49	4	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ADAMTSL1 FBN1 ADAMTSL3	4.97e-05	184	49	4	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH CCN6 FBN2 ADAMTSL3	5.07e-05	185	49	4	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	ADAMTS1 SPOCK1 DISP2 CUBN	5.07e-05	185	49	4	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SPOCK1 TJP1 CR1	5.07e-05	185	49	4	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	CFH ADAMTSL1 FBN1 ADAMTSL3	5.07e-05	185	49	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH CCN6 FBN2 ADAMTSL3	5.07e-05	185	49	4	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CFH MST1R FBN1 FBN2	5.29e-05	187	49	4	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	CFH CFHR1 MUC5B C4BPA	5.29e-05	187	49	4	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBN1 SLC6A15 ADAMTSL3	5.29e-05	187	49	4	7beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 PPM1E ADAMTSL3 CSMD3	5.29e-05	187	49	4	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH HIC2 FAM3B MUC5AC	5.29e-05	187	49	4	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH SCUBE1 FBN2 CSMD2	5.40e-05	188	49	4	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH FBN1 SPOCK1 ADAMTSL3	5.40e-05	188	49	4	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	Severe_COVID-19-Epithelial-undefined_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MST1R MUC5B TMC5 MUC5AC	5.51e-05	189	49	4	8cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CCN6 FBN1 ADAMTSL3	5.51e-05	189	49	4	6b3b42d758b63a0df62310c34fa3bde421c1afd7
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH ADAMTSL1 FBN1 SPOCK1	5.51e-05	189	49	4	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CCN6 FBN1 ADAMTSL3	5.51e-05	189	49	4	344b23d3c47d0665dda1cd4856a5e72f1c28cfb3
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 FBN1 SPOCK1 ADAMTSL3	5.63e-05	190	49	4	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	BL-critical-LOC-Epithelial-Secretory\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFH TJP1 MUC5B MUC5AC	5.63e-05	190	49	4	f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTSL1 FBN1 ADAMTSL3	5.63e-05	190	49	4	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	droplet-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ADAMTSL1 FBN1 ADAMTSL3	5.63e-05	190	49	4	2abeb013bb83c578e67dcb985ba44ca63134950b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH ADAMTSL1 FBN1 ADAMTSL3	5.63e-05	190	49	4	efb757f11c2809e66ddb48a5c84f5433f111cb7c
Computational	Genes in the cancer module 58.	CFH CFHR1 C4BPA	3.38e-05	21	33	3	MODULE_58
Computational	Complement.	CFH CFHR1 C4BPA	4.48e-05	23	33	3	MODULE_130
Computational	Neighborhood of IGFBP1	CFH C4BPA F12	6.89e-04	57	33	3	CAR_IGFBP1
Computational	Genes in the cancer module 46.	CFH MST1R CFHR1 SPOCK1 C4BPA CR1	1.12e-03	394	33	6	MODULE_46
Computational	Immune response.	CFH MST1R CFHR1 SPOCK1 C4BPA CR1	1.18e-03	398	33	6	MODULE_75
Computational	Neighborhood of HPX	CFH C4BPA F12	1.42e-03	73	33	3	CAR_HPX
Disease	thrombospondin type-1 domain-containing protein 7A measurement	CFH C4BPA	7.13e-06	3	46	2	EFO_0803150
Disease	anaphase-promoting complex subunit 7 measurement	CFH CFHR1	7.13e-06	3	46	2	EFO_0801381
Disease	HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1	CFH CFHR1	7.13e-06	3	46	2	C2749604
Disease	HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1	CFH CFHR1	7.13e-06	3	46	2	235400
Disease	calnexin measurement	CFH CFHR1	7.13e-06	3	46	2	EFO_0801444
Disease	complement factor H-related protein 4A measurement	CFH CFHR1	7.13e-06	3	46	2	EFO_0600057
Disease	Hemolytic uremic syndrome, atypical, susceptibility to, 1	CFH CFHR1	7.13e-06	3	46	2	cv:C2749604
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2	7.13e-06	3	46	2	DOID:65 (implicated_via_orthology)
Disease	histone-lysine N-methyltransferase 2D measurement	CFH CFHR1	7.13e-06	3	46	2	EFO_0801683
Disease	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement	CFH CFHR1	1.42e-05	4	46	2	EFO_0803292
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	1.42e-05	4	46	2	DOID:0060249 (is_implicated_in)
Disease	kallikrein-5 measurement	CFH CFHR1	1.42e-05	4	46	2	EFO_0020515
Disease	matrix extracellular phosphoglycoprotein measurement	CFH F12	2.37e-05	5	46	2	EFO_0020557
Disease	Membranoproliferative Glomerulonephritis, Type II	CFH CFHR1	3.55e-05	6	46	2	C0268743
Disease	progonadoliberin-1 measurement	CFH F12	3.55e-05	6	46	2	EFO_0801924
Disease	CD63 antigen measurement	CFH F12	3.55e-05	6	46	2	EFO_0022033
Disease	serine/threonine-protein kinase ULK3 measurement	CFH F12	3.55e-05	6	46	2	EFO_0803065
Disease	complement C1s subcomponent measurement	CFH CFHR1	3.55e-05	6	46	2	EFO_0008091
Disease	glucosidase 2 subunit beta measurement	CFH F12	3.55e-05	6	46	2	EFO_0801628
Disease	cadherin-15 measurement	CFH F12	4.97e-05	7	46	2	EFO_0020211
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	CFH CFHR1	6.62e-05	8	46	2	DOID:0080301 (is_implicated_in)
Disease	corneal resistance factor	KAT2B FBN1 FBN2 TJP1 SLC6A15 NPLOC4	6.88e-05	451	46	6	EFO_0010067
Disease	C3 glomerulopathy	CFH CFHR1	8.50e-05	9	46	2	C4087273
Disease	Atypical hemolytic-uremic syndrome	CFH CFHR1	8.50e-05	9	46	2	cv:C2931788
Disease	Hemolytic-uremic syndrome	CFH CFHR1	8.50e-05	9	46	2	cv:C0019061
Disease	leukocyte immunoglobulin-like receptor subfamily A member 5 measurement	CFH CFHR1	8.50e-05	9	46	2	EFO_0801766
Disease	Atypical Hemolytic Uremic Syndrome	CFH CFHR1	1.06e-04	10	46	2	C2931788
Disease	bone morphogenetic protein 7 measurement	CFH F12	1.06e-04	10	46	2	EFO_0020187
Disease	transmembrane glycoprotein NMB measurement	CFH F12	1.06e-04	10	46	2	EFO_0008303
Disease	atrophic macular degeneration, age-related macular degeneration, wet macular degeneration	CFH CFHR1 NPLOC4	1.14e-04	60	46	3	EFO_0001365, EFO_0004683, EFO_1001492
Disease	pulmonary fibrosis	MUC5B MUC5AC	1.30e-04	11	46	2	EFO_0009448
Disease	hemopexin measurement	CFH CFHR1	1.30e-04	11	46	2	EFO_0008149
Disease	age-related macular degeneration, COVID-19	CFH CFHR1 NPLOC4	1.73e-04	69	46	3	EFO_0001365, MONDO_0100096
Disease	transmembrane protein 87B measurement	CFH F12	1.83e-04	13	46	2	EFO_0802158
Disease	optic disc size measurement	KAT2B SLC6A15 ADAMTSL3 NPLOC4	2.94e-04	205	46	4	EFO_0004832
Disease	descending aortic diameter	CFH FBN1 DISP2	3.55e-04	88	46	3	EFO_0021788
Disease	Age-related macular degeneration	CFH CFHR1	3.58e-04	18	46	2	cv:C0242383
Disease	anorectal malformation	MUC5B CSMD2	4.00e-04	19	46	2	MONDO_0019938
Disease	glaucoma (is_marker_for)	CFH MUC5AC	4.44e-04	20	46	2	DOID:1686 (is_marker_for)
Disease	COVID-19 (is_implicated_in)	CFH C4BPA	4.90e-04	21	46	2	DOID:0080600 (is_implicated_in)
Disease	cup-to-disc ratio measurement	KAT2B ADAMTSL1 SLC6A15 ADAMTSL3 NPLOC4	5.38e-04	430	46	5	EFO_0006939
Disease	sorbitol measurement	ADAMTSL1 SLC6A15	5.89e-04	23	46	2	EFO_0010533
Disease	myeloperoxidase measurement	CFH PPM1E	7.55e-04	26	46	2	EFO_0005243
Disease	complement factor H-related protein 2 measurement	CFH CFHR1	9.40e-04	29	46	2	EFO_0600055
Disease	Age related macular degeneration	CFH CFHR1	1.01e-03	30	46	2	C0242383
Disease	cortical surface area measurement	SCUBE1 ADAMTSL1 FBN1 FBN2 TJP1 SLC6A15 ADAMTSL3 NPLOC4	1.02e-03	1345	46	8	EFO_0010736
Disease	Complement deficiency disease	CFH CFHR1	1.22e-03	33	46	2	C0272242
Disease	pelvic organ prolapse	ADAMTSL1 FBN2 TXN2	1.26e-03	136	46	3	EFO_0004710
Disease	primary dental caries	CFH CUBN	1.29e-03	34	46	2	EFO_0600095
Disease	central corneal thickness	FBN1 FBN2 TJP1 NPLOC4	1.36e-03	309	46	4	EFO_0005213
Disease	ascending aortic diameter	FBN1 FBN2 DISP2	1.37e-03	140	46	3	EFO_0021787
Disease	COVID-19 symptoms measurement	MUC5B MUC5AC	1.37e-03	35	46	2	EFO_0600019

Protein segments in the cluster

Peptide	Gene	Start	Entry
KWNPSPPACEPNSCI	C4BPA	286	P04003
WDHPLPKCEVPCGGN	CSMD2	2171	Q7Z408
NWNHPLPRCEALCGG	CSMD3	2271	Q7Z407
QQPPGAQGCPRCIWL	CXorf49;	476	A8MYA2
VCTKPIPCQPTHFWN	AACS	486	Q86V21
NPAIKWCPTPGCDRA	ANKIB1	416	Q9P2G1
TCRNGQWSEPPKCLH	CFH	1151	P08603
PEKNCGQILWPCAHL	DISP2	1116	A7MBM2
HAGGQPRNWRCPELC	MUC5B	311	Q9HC84
TRPCADHPCPQWQLG	ADAMTS1	901	Q9UHI8
RQCLSGCWPALPKPR	ESPNL	681	Q6ZVH7
CKCNGWKNPNPSPTP	KAT2B	106	Q92831
GPRPANWQRCNITPC	ADAMTSL1	1711	Q8N6G6
GHLPWPNGICTKCQP	NPLOC4	196	Q8TAT6
QDWRGPDFCPQKCPN	MUC5AC	326	P98088
PVPKRQKCDHWTPCP	FAM3B	56	P58499
KRPWPQHQCSAPADL	PPM1E	526	Q8WY54
APQRKQFCHWPCKCP	CCN6	41	O95389
QFCHWPCKCPQQKPR	CCN6	46	O95389
HDSFFCICPPQWKGP	CUBN	151	O60494
NGRWGPKLPHCSRVC	CR1	1636	P17927
SLCREHPWQGRCPPI	LINC00315	41	P59091
GRAWNKPCEQCPIPS	FBN1	1726	P35555
AWGHPCEMCPAQPQP	FBN2	246	P35556
CRNGQWSEPPKCLHP	CFHR1	251	Q03591
CEPCSNPHPLVWAKL	ZMYND8	271	Q9ULU4
CVCPPGRRLHWNGKD	SCUBE1	386	Q8IWY4
APQRPCHLKGWQHRP	SCNN1D	161	P51172
LFPAPRDCNPHCPWR	R3HDML	146	Q9H3Y0
RPVGCKWENPPHCLE	ODF2	76	Q5BJF6
LWDLCKGFCPQDRPP	FAM180B	156	Q6P0A1
CTHKGRPGPQPWCAT	F12	61	P00748
THWLTRPFPCNICGK	HIC2	526	Q96JB3
PLPWDQCPLVKNASH	SLC6A15	176	Q9H2J7
DALLDPNWHCPPCRG	CDCA7	311	Q9BWT1
PKECSSHQPCQGGPW	CLBA1	116	Q96F83
HAQWCGPCKILGPRL	TXN2	86	Q99757
DLCNPNGVGPWKLRC	PNMT	46	P11086
RLAAPDPCDPQRWCH	PRAF2	21	O60831
HWVGPSNLVKCKPCP	SPOCK1	126	Q08629
GKCCEEIQPHQWKPP	YY1AP1	351	Q9H869
PHCDPKTWQNKCLPG	TJP1	1716	Q07157
LQWCPKCCFHRPPRT	ZDHHC19	111	Q8WVZ1
HPCGWFCVPLKDNPN	STARD4	151	Q96DR4
NPPLSECDWHKSPQG	TMC5	336	Q6UXY8
KECPGSWQQDHCPPK	MST1R	556	Q04912
QPCSSGPWLPECHNK	TOE1	461	Q96GM8
LDNPARIPPCGWKCS	USP5	186	P45974
CPHPANPTWALRKGA	nan	126	Q6ZTC4
LHPSCCWKPDPDQVD	XKR8	341	Q9H6D3
LRPHTCPQCGKQFVW	ZNF641	261	Q96N77
WLTHTGEKPFQCPRC	ZNF641	391	Q96N77
RKPCFGHPCVQWEPG	ADAMTSL3	1536	P82987