Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	RAD51C KIF21B MYH2 MYH3 KIF23 ERCC3 TCP1 DNAH1 DDX11 RAD54B CCT6B HFM1 ATP13A3	8.45e-06	614	97	13	GO:0140657
GeneOntologyMolecularFunction	DNA helicase activity	ERCC3 DDX11 RAD54B HFM1	2.35e-04	62	97	4	GO:0003678
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF21B MYH2 MYH3 KIF23 DNAH1	2.77e-04	118	97	5	GO:0003774
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF21B MYH3 KIF23 ERCC3 TCP1 DDX11 CCT6B HFM1 ATP13A3	2.96e-04	441	97	9	GO:0016887
GeneOntologyMolecularFunction	U2 snRNA binding	RO60 SF3B3	3.46e-04	6	97	2	GO:0030620
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	RAD51C ERCC3 DDX11 RAD54B HFM1	3.88e-04	127	97	5	GO:0008094
GeneOntologyBiologicalProcess	nucleolar large rRNA transcription by RNA polymerase I	ERCC3 DDX11 POLR1F GTF2H5	6.09e-06	26	96	4	GO:0042790
GeneOntologyBiologicalProcess	transcription elongation by RNA polymerase I	ERCC3 POLR1F GTF2H5	8.04e-06	9	96	3	GO:0006362
GeneOntologyBiologicalProcess	rRNA transcription	ERCC3 DDX11 POLR1F GTF2H5	6.19e-05	46	96	4	GO:0009303
GeneOntologyCellularComponent	I-kappaB/NF-kappaB complex	NFKB1 NFKB2	1.30e-04	4	98	2	GO:0033256
Domain	IPT_NFkappaB	NFKB1 NFKB2	2.53e-04	5	95	2	IPR033926
Domain	RHD_CS	NFKB1 NFKB2	2.53e-04	5	95	2	IPR030492
Domain	IPT	NFKB1 NFKB2 PLXNB1	3.41e-04	27	95	3	SM00429
Domain	P-loop_NTPase	RAD51C KIF21B MYH2 MYH3 RAP1A KIF23 ERCC3 DNAH1 DDX11 HNRNPUL2 RAD54B HFM1 DIRAS2	3.54e-04	848	95	13	IPR027417
Domain	Ig_I-set	FLT1 MXRA5 DSCAM IGDCC3 TYRO3 FGFR3	4.20e-04	190	95	6	IPR013098
Domain	I-set	FLT1 MXRA5 DSCAM IGDCC3 TYRO3 FGFR3	4.20e-04	190	95	6	PF07679
Domain	-	FLT1 MXRA5 DSCAM IGDCC3 TYRO3 TRIM45 NFKB1 NFKB2 FGFR3 FLRT1 PLXNB1	5.41e-04	663	95	11	2.60.40.10
Domain	IPT	NFKB1 NFKB2 PLXNB1	5.68e-04	32	95	3	IPR002909
Domain	Cadherin_tail	PCDHAC2 PCDHA8 PCDHA7	8.74e-04	37	95	3	PF15974
Domain	Cadherin_CBD	PCDHAC2 PCDHA8 PCDHA7	8.74e-04	37	95	3	IPR031904
Domain	Chaprnin_Cpn60	TCP1 CCT6B	9.00e-04	9	95	2	IPR001844
Domain	Chaperonin_TCP-1_CS	TCP1 CCT6B	9.00e-04	9	95	2	IPR002194
Domain	Ig-like_fold	FLT1 MXRA5 DSCAM IGDCC3 TYRO3 TRIM45 NFKB1 NFKB2 FGFR3 FLRT1 PLXNB1	9.08e-04	706	95	11	IPR013783
Domain	RHD_dimer	NFKB1 NFKB2	1.12e-03	10	95	2	IPR032397
Domain	RHD_dimer	NFKB1 NFKB2	1.12e-03	10	95	2	PF16179
Domain	REL_1	NFKB1 NFKB2	1.12e-03	10	95	2	PS01204
Domain	TCP1_1	TCP1 CCT6B	1.12e-03	10	95	2	PS00750
Domain	TCP1_2	TCP1 CCT6B	1.12e-03	10	95	2	PS00751
Domain	TCP1_3	TCP1 CCT6B	1.12e-03	10	95	2	PS00995
Domain	-	NFKB1 NFKB2	1.12e-03	10	95	2	2.60.40.340
Domain	NFkB/Dor	NFKB1 NFKB2	1.12e-03	10	95	2	IPR000451
Domain	RHD_DNA_bind_dom	NFKB1 NFKB2	1.12e-03	10	95	2	IPR011539
Domain	RHD_DNA_bind	NFKB1 NFKB2	1.12e-03	10	95	2	PF00554
Domain	REL_2	NFKB1 NFKB2	1.12e-03	10	95	2	PS50254
Domain	Chaperone_TCP-1	TCP1 CCT6B	1.12e-03	10	95	2	IPR017998
Domain	IGc2	FLT1 MXRA5 DSCAM IGDCC3 TYRO3 FGFR3	1.27e-03	235	95	6	SM00408
Domain	Ig_sub2	FLT1 MXRA5 DSCAM IGDCC3 TYRO3 FGFR3	1.27e-03	235	95	6	IPR003598
Domain	-	TCP1 CCT6B	1.37e-03	11	95	2	3.30.260.10
Domain	TCP-1-like_intermed	TCP1 CCT6B	1.37e-03	11	95	2	IPR027410
Domain	Integrin_alpha	ITGA7 ITGAV	1.37e-03	11	95	2	PF00357
Domain	Ig_E-set	TRIM45 NFKB1 NFKB2 PLXNB1	1.96e-03	104	95	4	IPR014756
Domain	GROEL-like_equatorial	TCP1 CCT6B	2.24e-03	14	95	2	IPR027413
Domain	-	TCP1 CCT6B	2.24e-03	14	95	2	1.10.560.10
Domain	GroEL-like_apical_dom	TCP1 CCT6B	2.57e-03	15	95	2	IPR027409
Domain	Cpn60/TCP-1	TCP1 CCT6B	2.57e-03	15	95	2	IPR002423
Domain	Cpn60_TCP1	TCP1 CCT6B	2.57e-03	15	95	2	PF00118
Domain	-	TCP1 CCT6B	2.57e-03	15	95	2	3.50.7.10
Domain	Myosin_N	MYH2 MYH3	2.57e-03	15	95	2	PF02736
Domain	Myosin_N	MYH2 MYH3	2.57e-03	15	95	2	IPR004009
Domain	ig	FLT1 DSCAM IGDCC3 TYRO3 FGFR3	2.86e-03	190	95	5	PF00047
Domain	Immunoglobulin	FLT1 DSCAM IGDCC3 TYRO3 FGFR3	2.86e-03	190	95	5	IPR013151
Domain	Integrin_alpha_C_CS	ITGA7 ITGAV	2.93e-03	16	95	2	IPR018184
Domain	Integrin_alpha-2	ITGA7 ITGAV	3.71e-03	18	95	2	IPR013649
Domain	Myosin_tail_1	MYH2 MYH3	3.71e-03	18	95	2	PF01576
Domain	Myosin_tail	MYH2 MYH3	3.71e-03	18	95	2	IPR002928
Domain	INTEGRIN_ALPHA	ITGA7 ITGAV	3.71e-03	18	95	2	PS00242
Domain	Integrin_alpha2	ITGA7 ITGAV	3.71e-03	18	95	2	PF08441
Domain	Integrin_alpha	ITGA7 ITGAV	3.71e-03	18	95	2	IPR000413
Domain	Int_alpha	ITGA7 ITGAV	4.14e-03	19	95	2	SM00191
Domain	Myosin-like_IQ_dom	MYH2 MYH3	4.14e-03	19	95	2	IPR027401
Domain	-	MYH2 MYH3	4.14e-03	19	95	2	4.10.270.10
Domain	Int_alpha_beta-p	ITGA7 ITGAV	4.14e-03	19	95	2	IPR013519
Domain	Cadherin_2	PCDHAC2 PCDHA8 PCDHA7	4.43e-03	65	95	3	PF08266
Domain	Cadherin_N	PCDHAC2 PCDHA8 PCDHA7	4.43e-03	65	95	3	IPR013164
Domain	RCC1	NEK9 NEK8	4.58e-03	20	95	2	PF00415
Domain	RCC1_1	NEK9 NEK8	5.05e-03	21	95	2	PS00625
Domain	RCC1_2	NEK9 NEK8	5.05e-03	21	95	2	PS00626
Domain	RCC1_3	NEK9 NEK8	5.05e-03	21	95	2	PS50012
Pubmed	Differential onset of expression of alpha 7 and beta 1D integrins during mouse heart and skeletal muscle development.	VWF ITGA7 ITGAV	4.31e-07	6	98	3	9686317
Pubmed	Suppression of HIV-1 Tat-induced monocyte adhesiveness by a cell-permeable superoxide dismutase in astrocytes.	NFKB1 NFKB2 SOD1	4.69e-06	12	98	3	18160848
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	KIF23 ERCC3 TCP1 IARS1 THUMPD3 NEK9 POLR1F GTF2I SF3B3 SEC24C HNRNPUL2 NFKB2 MDC1 CCT6B PKN2	5.78e-06	1353	98	15	29467282
Pubmed	Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.	NFKB1 NFKB2	7.86e-06	2	98	2	25482563
Pubmed	Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype.	NFKB1 NFKB2	7.86e-06	2	98	2	28368397
Pubmed	Expression of either NF-kappaB p50 or p52 in osteoclast precursors is required for IL-1-induced bone resorption.	NFKB1 NFKB2	7.86e-06	2	98	2	12568403
Pubmed	NF-kappaB to the rescue: RELs, apoptosis and cellular transformation.	NFKB1 NFKB2	7.86e-06	2	98	2	10354583
Pubmed	Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice.	FLT1 VWF	7.86e-06	2	98	2	9689083
Pubmed	Osteoclast precursor interaction with bone matrix induces osteoclast formation directly by an interleukin-1-mediated autocrine mechanism.	NFKB1 NFKB2	7.86e-06	2	98	2	18250170
Pubmed	New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases.	NFKB1 NFKB2	7.86e-06	2	98	2	9895331
Pubmed	Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.	RAD54B SOD1	7.86e-06	2	98	2	24002644
Pubmed	Induction of endothelial cell proliferation and von Willebrand factor expression and secretion by leukemic plasma of patients with chronic lymphocytic leukemia before and after inhibition of NF-κB.	VWF NFKB1	7.86e-06	2	98	2	27472040
Pubmed	How do nuclear factor kappa B (NF-κB)1 and NF-κB2 defects lead to the incidence of clinical and immunological manifestations of inborn errors of immunity?	NFKB1 NFKB2	7.86e-06	2	98	2	36706462
Pubmed	TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways.	SATB2 NFKB1	7.86e-06	2	98	2	29435145
Pubmed	Transforming growth factor-beta1-mediated activation of NF-kappaB contributes to enhanced ADAM-12 expression in mammary carcinoma cells.	ADAM12 NFKB1	7.86e-06	2	98	2	20688878
Pubmed	Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors.	NEK9 NEK8	7.86e-06	2	98	2	15019993
Pubmed	Related subunits of NF-kappa B map to two distinct loci associated with translocations in leukemia, NFKB1 and NFKB2.	NFKB1 NFKB2	7.86e-06	2	98	2	1612589
Pubmed	The role of NF-{kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas.	NFKB1 NFKB2	7.86e-06	2	98	2	16751281
Pubmed	Alterations in the expression of genes related to NF-κB signaling in liver and kidney of CuZnSOD-deficient mice.	NFKB1 SOD1	7.86e-06	2	98	2	21472504
Pubmed	Identification of genes showing differential expression in anorexia mutant mouse.	GRIA1 TYRO3	7.86e-06	2	98	2	12802202
Pubmed	Monitoring a nuclear factor-κB signature of drug resistance in multiple myeloma.	NFKB1 NFKB2	7.86e-06	2	98	2	21846842
Pubmed	A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.	NFKB1 HTT	7.86e-06	2	98	2	25938884
Pubmed	NF-kappa B binds to the immunoglobulin S gamma 3 region in vivo during class switch recombination.	NFKB1 NFKB2	7.86e-06	2	98	2	17109470
Pubmed	Requirement for NF-kappaB in osteoclast and B-cell development.	NFKB1 NFKB2	7.86e-06	2	98	2	9407039
Pubmed	Analysis of NFKB1 and NFKB2 gene expression in the blood of patients with sudden sensorineural hearing loss.	NFKB1 NFKB2	7.86e-06	2	98	2	36773447
Pubmed	NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4.	NFKB1 NFKB2	7.86e-06	2	98	2	15677444
Pubmed	Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.	NFKB1 NFKB2	7.86e-06	2	98	2	9359707
Pubmed	Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.	PCDHAC2 PCDHA8 PCDHA7	9.63e-06	15	98	3	15640798
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	RAP1A TCP1 RO60 SF3B3 GTF2H5 PKN2 PLS3	1.22e-05	271	98	7	25737280
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	DPYSL3 SATB2 TCP1 NEK9 GTF2I SF3B3 MDC1 CCT6B PLS3	1.36e-05	506	98	9	30890647
Pubmed	Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.	PCDHAC2 PCDHA8 PCDHA7	1.43e-05	17	98	3	29911975
Pubmed	Genome cross-referencing and XREFdb: implications for the identification and analysis of genes mutated in human disease.	FGFR3 SOD1 HTT	1.72e-05	18	98	3	9090377
Pubmed	CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.	PCDHAC2 PCDHA8 PCDHA7	1.72e-05	18	98	3	15570159
Pubmed	Genomic organization of the family of CNR cadherin genes in mice and humans.	PCDHAC2 PCDHA8 PCDHA7	1.72e-05	18	98	3	10662547
Pubmed	Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis.	FLT1 VWF	2.35e-05	3	98	2	7683699
Pubmed	Association of GTF2I, NFKB1, and TYK2 Regional Polymorphisms With Systemic Sclerosis in a Chinese Han Population.	GTF2I NFKB1	2.35e-05	3	98	2	34248934
Pubmed	TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease.	TCP1 HTT	2.35e-05	3	98	2	27601642
Pubmed	Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3).	NFKB1 NFKB2	2.35e-05	3	98	2	8441377
Pubmed	Nuclear transcription factor-kappaB as a target for cancer drug development.	NFKB1 NFKB2	2.35e-05	3	98	2	12040437
Pubmed	The NF-kappa B and I kappa B proteins: new discoveries and insights.	NFKB1 NFKB2	2.35e-05	3	98	2	8717528
Pubmed	Motif module map reveals enforcement of aging by continual NF-kappaB activity.	NFKB1 NFKB2	2.35e-05	3	98	2	18055696
Pubmed	NF-κB: an essential transcription factor in psoriasis.	NFKB1 NFKB2	2.35e-05	3	98	2	23219896
Pubmed	NFkappaB1/p50 is not required for tumor necrosis factor-stimulated growth of primary mammary epithelial cells: implications for NFkappaB2/p52 and RelB.	NFKB1 NFKB2	2.35e-05	3	98	2	17008396
Pubmed	Flt-1 expression influences apoptotic susceptibility of vascular smooth muscle cells through the NF-kappaB/IAP-1 pathway.	FLT1 NFKB1	2.35e-05	3	98	2	19720604
Pubmed	High-resolution mapping of tlt, a mouse mutant lacking otoconia.	FGFR3 HTT	2.35e-05	3	98	2	10341082
Pubmed	Signaling mediated by the NF-κB sub-units NF-κB1, NF-κB2 and c-Rel differentially regulate Helicobacter felis-induced gastric carcinogenesis in C57BL/6 mice.	NFKB1 NFKB2	2.35e-05	3	98	2	23975431
Pubmed	[The Rel/NF-kappa-B transcription factors: complex role in cell regulation].	NFKB1 NFKB2	2.35e-05	3	98	2	11980335
Pubmed	Genetic variants in the VEGF pathway as prognostic factors in stages II and III colon cancer.	FLT1 ITGAV	2.35e-05	3	98	2	29282362
Pubmed	CD40 Signaling in Graves Disease Is Mediated Through Canonical and Noncanonical Thyroidal Nuclear Factor κB Activation.	NFKB1 NFKB2	2.35e-05	3	98	2	27929668
Pubmed	Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.	NFKB1 NFKB2	2.35e-05	3	98	2	28726772
Pubmed	Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3.	NFKB1 NFKB2	2.35e-05	3	98	2	12055593
Pubmed	Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity.	NFKB1 NFKB2	2.35e-05	3	98	2	18624726
Pubmed	Deregulated Levels of the NF-κB1, NF-κB2, and Rel Genes in Ukrainian Patients with Leukemia and Lymphoma in the Post-Chernobyl Period.	NFKB1 NFKB2	2.35e-05	3	98	2	25912249
Pubmed	Lipopolysaccharide from Salmonella enterica activates NF-kappaB through both classical and alternative pathways in primary B Lymphocytes.	NFKB1 NFKB2	2.35e-05	3	98	2	17698569
Pubmed	Differential regulation of the von Willebrand factor and Flt-1 promoters in the endothelium of hypoxanthine phosphoribosyltransferase-targeted mice.	FLT1 VWF	2.35e-05	3	98	2	12393668
Pubmed	Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway.	NFKB1 NFKB2	2.35e-05	3	98	2	12969313
Pubmed	NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis.	NFKB1 NFKB2	2.35e-05	3	98	2	12096833
Pubmed	Solid-phase von Willebrand factor contains a conformationally active RGD motif that mediates endothelial cell adhesion through the alpha v beta 3 receptor.	VWF ITGAV	2.35e-05	3	98	2	7505120
Pubmed	Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation.	NFKB1 NFKB2	2.35e-05	3	98	2	12370384
Pubmed	Epigenetic modifications and NF-κB pathway activity in Cu,Zn-SOD-deficient mice.	NFKB1 SOD1	2.35e-05	3	98	2	25138704
Pubmed	Cell-autonomous role for NF-kappa B in immature bone marrow B cells.	NFKB1 NFKB2	2.35e-05	3	98	2	19265118
Pubmed	TFIIH subunit alterations causing xeroderma pigmentosum and trichothiodystrophy specifically disturb several steps during transcription.	ERCC3 GTF2H5	2.35e-05	3	98	2	25620205
Pubmed	Reciprocal regulation of p53 and NF-κB by diacylglycerol kinase ζ.	DGKZ NFKB1	2.35e-05	3	98	2	26521214
Pubmed	1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells.	NFKB1 NFKB2	2.35e-05	3	98	2	17507908
Pubmed	Integrin alpha(v)beta(3) on human endothelial cells binds von Willebrand factor strings under fluid shear stress.	VWF ITGAV	2.35e-05	3	98	2	18927433
Pubmed	Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB.	NFKB1 NFKB2	2.35e-05	3	98	2	11468175
Pubmed	Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models.	GRIA1 HTT	2.35e-05	3	98	2	30323233
Pubmed	Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues.	NFKB1 NFKB2	2.35e-05	3	98	2	16195333
Pubmed	Thymosin beta10 inhibits cell migration and capillary-like tube formation of human coronary artery endothelial cells.	FLT1 ITGAV	2.35e-05	3	98	2	16496302
Pubmed	Plexin-B1, glycodelin and MMP7 expression in the human fallopian tube and in the endometrium.	PAEP PLXNB1	2.35e-05	3	98	2	20040080
Pubmed	The relationship between BRAFV600E, NF-κB and TgAb expression in papillary thyroid carcinoma.	NFKB1 NFKB2	2.35e-05	3	98	2	28214213
Pubmed	NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro.	NFKB1 NFKB2	2.35e-05	3	98	2	12759356
Pubmed	NF-kappa B p50/p65 affects the frequency of Ly49 gene expression by NK cells.	NFKB1 NFKB2	2.35e-05	3	98	2	17641041
Pubmed	Human Adenovirus Type 26 Induced IL-6 Gene Expression in an αvβ3 Integrin- and NF-κB-Dependent Manner.	ITGAV NFKB1	2.35e-05	3	98	2	35458402
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	DPYSL3 KIF23 TCP1 NEK9 GTF2I MDC1 PKN2 PLS3 HTT	2.58e-05	549	98	9	38280479
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DPYSL3 GRN ITGA7 ITGAV ADAM12 NEK9 NUP35 SEC24C HNRNPUL2 FAM3C PLS3 PLXNB1 HTT	3.29e-05	1201	98	13	35696571
Pubmed	Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.	PCDHAC2 PCDHA8 PCDHA7	4.21e-05	24	98	3	24698270
Pubmed	Impact of loss of NF-κB1, NF-κB2 or c-REL on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice.	NFKB1 NFKB2	4.70e-05	4	98	2	26084385
Pubmed	Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription.	NFKB1 NFKB2	4.70e-05	4	98	2	1583734
Pubmed	Stimulation of CD30 in anaplastic large cell lymphoma leads to production of nuclear factor-kappaB p52, which is associated with hyperphosphorylated Bcl-3.	NFKB1 NFKB2	4.70e-05	4	98	2	16108830
Pubmed	The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta.	RBL1 DGKZ	4.70e-05	4	98	2	16286473
Pubmed	Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.	MYH2 MYH3	4.70e-05	4	98	2	20357587
Pubmed	NF-κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome.	NFKB1 NFKB2	4.70e-05	4	98	2	28804991
Pubmed	Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.	GRN TYRO3	4.70e-05	4	98	2	29382817
Pubmed	Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes.	NFKB1 NFKB2	4.70e-05	4	98	2	7729429
Pubmed	A CNS-enriched factor that binds to NF-kappa B and is required for interaction with HIV-1 tat.	NFKB1 NFKB2	4.70e-05	4	98	2	7838536
Pubmed	Targeting nuclear factor-κB suppresses the negative effect of toll-like receptor 4 signaling on antimetastasis therapy based on targeting αvβ3.	ITGAV NFKB1	4.70e-05	4	98	2	22494046
Pubmed	TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation.	NFKB1 NFKB2	4.70e-05	4	98	2	1505523
Pubmed	VEGF-C, a lymphatic growth factor, is a RANKL target gene in osteoclasts that enhances osteoclastic bone resorption through an autocrine mechanism.	NFKB1 NFKB2	4.70e-05	4	98	2	18359770
Pubmed	The VWF/LRP4/αVβ3-axis represents a novel pathway regulating proliferation of human vascular smooth muscle cells.	VWF ITGAV	4.70e-05	4	98	2	33576766
Pubmed	Transfection of human endothelial cells with HIV-1 tat gene activates NF-kappa B and enhances monocyte adhesion.	NFKB1 NFKB2	4.70e-05	4	98	2	12427593
Pubmed	Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD.	GRN SOD1	4.70e-05	4	98	2	17166276
Pubmed	Dynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cells.	ERCC3 GTF2H5	4.70e-05	4	98	2	16669699
Pubmed	NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice.	NFKB1 NFKB2	4.70e-05	4	98	2	25727407
Pubmed	Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis.	NFKB1 NFKB2	4.70e-05	4	98	2	18505785
Pubmed	The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation.	NFKB1 NFKB2	4.70e-05	4	98	2	11526476
Pubmed	A fourth IkappaB protein within the NF-kappaB signaling module.	NFKB1 NFKB2	4.70e-05	4	98	2	17254973
Pubmed	αvβ3 Integrins Mediate Flow-Induced NF-κB Activation, Proinflammatory Gene Expression, and Early Atherogenic Inflammation.	ITGAV NFKB1	4.70e-05	4	98	2	26212910
Pubmed	Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors.	NFKB1 NFKB2	4.70e-05	4	98	2	7823959
Pubmed	Activation of noncanonical NF-kappaB signaling by the oncoprotein Tio.	NFKB1 NFKB2	4.70e-05	4	98	2	20353939
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	FLT1 MXRA5 DSCAM IGDCC3 TYRO3 FGFR3	2.03e-05	161	63	6	593
GeneFamily	General transcription factors\|Xeroderma pigmentosum complementation groups\|DNA helicases\|ERCC excision repair associated	ERCC3 GTF2I GTF2H5	8.78e-05	25	63	3	565
GeneFamily	Ankyrin repeat domain containing\|NF-kappa B complex subunits	NFKB1 NFKB2	1.19e-04	5	63	2	1254
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	FLT1 TYRO3 FGFR3	3.63e-04	40	63	3	321
GeneFamily	Chaperonins	TCP1 CCT6B	1.22e-03	15	63	2	587
GeneFamily	Myosin heavy chains	MYH2 MYH3	1.22e-03	15	63	2	1098
GeneFamily	Clustered protocadherins	PCDHAC2 PCDHA8 PCDHA7	1.44e-03	64	63	3	20
GeneFamily	DNA helicases	ERCC3 DDX11	1.57e-03	17	63	2	1167
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA7 ITGAV	1.76e-03	18	63	2	1160
GeneFamily	Fibronectin type III domain containing	DSCAM IGDCC3 TYRO3 FLRT1	2.35e-03	160	63	4	555
GeneFamily	Immunoglobulin like domain containing	FLT1 MXRA5 DSCAM TYRO3	4.59e-03	193	63	4	594
GeneFamily	RAS type GTPase family	RAP1A DIRAS2	5.21e-03	31	63	2	389
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF23	1.12e-02	46	63	2	622
Coexpression	DARWICHE_PAPILLOMA_RISK_HIGH_DN	TCP1 MSI1 TYRO3 DIP2A GTF2I CCT6B SOD1	6.27e-06	185	98	7	M1137
Coexpression	DARWICHE_PAPILLOMA_RISK_HIGH_DN	TCP1 MSI1 TYRO3 DIP2A GTF2I CCT6B SOD1	1.08e-05	201	98	7	MM500
Coexpression	YAGI_AML_WITH_INV_16_TRANSLOCATION	RAD51C RNASEH2B FLT1 DPYSL3 KIF23 PDHA2 NEK9 FLRT1 PLS3	2.41e-05	411	98	9	M1047
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF DSCAM RO60 TRIM45 HFM1 PLS3	2.57e-06	176	98	6	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF DSCAM RO60 TRIM45 HFM1 PLS3	2.57e-06	176	98	6	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	DPYSL3 MXRA5 IGDCC3 PTGFR FGFR3 PLS3	4.78e-06	196	98	6	57df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DPYSL3 SATB2 MXRA5 ADAM12 FGFR3 PLS3	5.06e-06	198	98	6	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IGDCC3 MSI1 NEK8 RAD54B FLRT1	2.31e-05	154	98	5	44d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCell	facs-Lung-EPCAM-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 MAP10 HFM1 NEIL3 SOD1	2.46e-05	156	98	5	bb64bf520cb74897a01c64924a85a1550df2b801
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF21B KIF23 RBL1 THYN1 RAD54B	2.78e-05	160	98	5	5cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT3 PCDHA8 RO60 NEK9 PLXNB1	3.04e-05	163	98	5	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SATB2 MXRA5 ADAM12 PTGFR FGFR3	4.62e-05	178	98	5	8f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAV ADAM12 NFKB1 SORCS3 ATP13A3	4.62e-05	178	98	5	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 ADAM12 DDX11 SLC9B2 NEIL3	4.75e-05	179	98	5	df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAD51C FLT1 TRIM45 THYN1 RAD54B	4.75e-05	179	98	5	327cc39161741ddbc4e8d45b9b3d30b3ce508929
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SATB2 DNAAF11 ADAM12 TYRO3 DIRAS2	5.00e-05	181	98	5	58f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF IGDCC3 FAM3C ATP13A3 FLRT1	5.13e-05	182	98	5	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT1 VWF FAM3C ATP13A3 FLRT1	5.13e-05	182	98	5	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT1 VWF FAM3C ATP13A3 FLRT1	5.13e-05	182	98	5	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF IGDCC3 FAM3C ATP13A3 FLRT1	5.13e-05	182	98	5	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR8 IGDCC3 GRIA1 ADAM12 FGFR3	5.27e-05	183	98	5	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WNT3 GZMK RAD54B SLC9B2 NEIL3	5.41e-05	184	98	5	1edefa2a049d7e22d0bdb1ea3d7ef1c8d6ae0fe3
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WNT3 GZMK RAD54B SLC9B2 NEIL3	5.41e-05	184	98	5	8578c50eaa8ce1cefc0228185c66c8e25f4bfc32
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 VWF ARMCX6 ATP13A3 SOD1	5.41e-05	184	98	5	8ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCXD1 PAQR8 IGDCC3 GRIA1 FGFR3	5.41e-05	184	98	5	f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR8 IGDCC3 GRIA1 ADAM12 FGFR3	5.55e-05	185	98	5	dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma-osteoclast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	WNT3 GRN ITGAV SLC9B2 DIRAS2	5.55e-05	185	98	5	5ed49b6d8214c6119355a6d3ee4e25d40bcc0c53
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR8 IGDCC3 GRIA1 ADAM12 FGFR3	5.55e-05	185	98	5	bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCell	Mesenchymal_cells-Osteo-CAR\|World / Lineage and Cell class	DPYSL3 SATB2 PTGFR CYP2U1 FGFR3	5.55e-05	185	98	5	16f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 VWF FAM3C ATP13A3 FLRT1	5.69e-05	186	98	5	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 VWF ARMCX6 FAM3C ATP13A3	5.84e-05	187	98	5	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 VWF ARMCX6 ATP13A3 FGFR3	5.99e-05	188	98	5	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 VWF ARMCX6 FAM3C PLS3	5.99e-05	188	98	5	59f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 DSCAM ADAM12 SORCS3 FLRT1	5.99e-05	188	98	5	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 DSCAM ADAM12 SORCS3 FLRT1	5.99e-05	188	98	5	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 VWF ARMCX6 FAM3C ATP13A3	6.14e-05	189	98	5	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACACB GRN ADAM12 DNAH1 HNRNPUL2	6.30e-05	190	98	5	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 VWF ARMCX6 FAM3C ATP13A3	6.30e-05	190	98	5	d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 VWF ARMCX6 FAM3C ATP13A3	6.45e-05	191	98	5	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 VWF ARMCX6 FAM3C ATP13A3	6.61e-05	192	98	5	285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DPYSL3 ITGA7 ITGAV ADAM12 PLS3	6.95e-05	194	98	5	f44394c8a6f86483063f2f5722f003a8a0a70254
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 RBL1 RAD54B NEIL3 ATP13A3	6.95e-05	194	98	5	effd38e51062b225ecabc7e1c50154e65495d559
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SATB2 MSI1 ADAM12 FGFR3 PLS3	7.47e-05	197	98	5	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FBXW10B KIF23 DNAAF11 PAEP CCDC171	7.47e-05	197	98	5	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	DPYSL3 MXRA5 DDX11 FGFR3 PLXNB1	7.47e-05	197	98	5	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DPYSL3 SATB2 MXRA5 ADAM12 FGFR3	7.47e-05	197	98	5	2f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DPYSL3 SATB2 MXRA5 ADAM12 PLS3	7.65e-05	198	98	5	55d2ed345101bec4b73f1242ba8c4d73073b7e88
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DPYSL3 SATB2 MXRA5 ADAM12 PLS3	7.65e-05	198	98	5	8602a518b5913625b1dd3cbc3c7e6efde0d5d942
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SATB2 MXRA5 ADAM12 FGFR3 PLS3	7.83e-05	199	98	5	d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SATB2 MXRA5 ADAM12 FGFR3 PLS3	7.83e-05	199	98	5	7b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SATB2 MXRA5 ADAM12 FGFR3 PLS3	7.83e-05	199	98	5	f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SATB2 MXRA5 ADAM12 FGFR3 PLS3	7.83e-05	199	98	5	bf138cc692df727e087d140c014149ee5da00d9d
ToppCell	Transverse-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	KIF23 RBL1 WFDC3 NEIL3 CCDC171	7.83e-05	199	98	5	170ae68963d31f3b821b6f0e8f0c039bea0bc981
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	DPYSL3 SATB2 MXRA5 ADAM12 PLS3	8.02e-05	200	98	5	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	DPYSL3 SATB2 MXRA5 ADAM12 PLS3	8.02e-05	200	98	5	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYSL3 MSI1 ADAM12 FLRT1 PLS3	8.02e-05	200	98	5	553e9612874480f4d2a45671462e266cd0a09321
Drug	lead compounds	ERCC3 PLCXD1 GRIA1 ITGAV NFKB1 NFKB2 PKN2	3.92e-06	150	98	7	CID000073212
Drug	thalidomide	FLT1 VWF ACTRT3 IFNA2 GTF2I NFKB1 NFKB2 PLS3	6.70e-06	229	98	8	CID000005426
Disease	corneal neovascularization (implicated_via_orthology)	FLT1 ITGAV	1.03e-05	2	95	2	DOID:11382 (implicated_via_orthology)
Disease	Photosensitive Trichothiodystrophy	ERCC3 GTF2H5	6.13e-05	4	95	2	C1866504
Disease	Trichothiodystrophy Syndromes	ERCC3 GTF2H5	1.53e-04	6	95	2	C1955934
Disease	Malignant neoplasm of breast	RAD51C FLT1 ERCC3 VWF TCP1 AQP8 MSI1 ADAM12 IFNA2 PAEP PLS3 PLXNB1	1.72e-04	1074	95	12	C0006142
Disease	Acute kidney injury	EPHX2 IFNA2 NFKB1 SOD1	3.24e-04	101	95	4	C2609414
Disease	Acute Kidney Insufficiency	EPHX2 IFNA2 NFKB1 SOD1	3.24e-04	101	95	4	C1565662
Disease	Kidney Failure, Acute	EPHX2 IFNA2 NFKB1 SOD1	3.24e-04	101	95	4	C0022660
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	NFKB1 NFKB2	3.64e-04	9	95	2	DOID:0050340 (implicated_via_orthology)
Disease	handedness	MYH3 SCN11A WNT3 ITGAV	3.90e-04	106	95	4	EFO_0009902
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH2 MYH3	4.54e-04	10	95	2	DOID:0080326 (implicated_via_orthology)
Disease	Immunoglobulin Deficiency, Late-Onset	NFKB1 NFKB2	5.54e-04	11	95	2	C2936665
Disease	Acquired Hypogammaglobulinemia	NFKB1 NFKB2	5.54e-04	11	95	2	C2936664
Disease	distal myopathy (implicated_via_orthology)	MYH2 MYH3	6.63e-04	12	95	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH2 MYH3	6.63e-04	12	95	2	DOID:2106 (implicated_via_orthology)
Disease	Common variable immunodeficiency	NFKB1 NFKB2	7.82e-04	13	95	2	cv:C0009447
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH2 MYH3	7.82e-04	13	95	2	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH2 MYH3	1.05e-03	15	95	2	DOID:0050646 (implicated_via_orthology)
Disease	Common Variable Immunodeficiency	NFKB1 NFKB2	1.05e-03	15	95	2	C0009447
Disease	neurodegenerative disease (implicated_via_orthology)	GRIA1 NFKB1 NFKB2 HTT	1.26e-03	145	95	4	DOID:1289 (implicated_via_orthology)
Disease	non-alcoholic steatohepatitis (biomarker_via_orthology)	NFKB1 SOD1	1.35e-03	17	95	2	DOID:0080547 (biomarker_via_orthology)
Disease	MHPG measurement, 5-HIAA measurement	ADAM12 CCDC171	1.35e-03	17	95	2	EFO_0005132, EFO_0005133
Disease	cardiomyopathy (implicated_via_orthology)	MYH2 MYH3 ITGA7	1.58e-03	71	95	3	DOID:0050700 (implicated_via_orthology)
Disease	bipolar disorder (is_marker_for)	VWF GRN	1.69e-03	19	95	2	DOID:3312 (is_marker_for)
Disease	dyslexia	SATB2 ITGAV CCDC171 HTT	1.89e-03	162	95	4	EFO_0005424
Disease	Lymphoma, Diffuse	IFNA2 RAD54B	2.07e-03	21	95	2	C3714542
Disease	Low Grade Lymphoma (neoplasm)	IFNA2 RAD54B	2.07e-03	21	95	2	C0079747
Disease	Lymphoma, Intermediate-Grade	IFNA2 RAD54B	2.07e-03	21	95	2	C0079741
Disease	High Grade Lymphoma (neoplasm)	IFNA2 RAD54B	2.07e-03	21	95	2	C0079740
Disease	Diffuse Mixed-Cell Lymphoma	IFNA2 RAD54B	2.07e-03	21	95	2	C0079757
Disease	Lymphoma, Undifferentiated	IFNA2 RAD54B	2.07e-03	21	95	2	C0024306
Disease	Reticulosarcoma	IFNA2 RAD54B	2.07e-03	21	95	2	C0024302
Disease	Lymphoma, Mixed-Cell	IFNA2 RAD54B	2.07e-03	21	95	2	C0024304
Disease	Hepatitis, Chronic	IFNA2 SOD1	2.27e-03	22	95	2	C0019189
Disease	Chronic active hepatitis	IFNA2 SOD1	2.27e-03	22	95	2	C0520463
Disease	triacylglycerol 58:9 measurement	NFKB2 CCT6B	2.27e-03	22	95	2	EFO_0010443
Disease	Chronic Persistent Hepatitis	IFNA2 SOD1	2.27e-03	22	95	2	C0149519
Disease	Lymphoma, Non-Hodgkin, Familial	IFNA2 RAD54B	2.27e-03	22	95	2	C4721532
Disease	Lymphoma, Small Noncleaved-Cell	IFNA2 RAD54B	2.27e-03	22	95	2	C0079770
Disease	Cryptogenic Chronic Hepatitis	IFNA2 SOD1	2.27e-03	22	95	2	C0524611
Disease	Depressive disorder	GRIA1 GRN IFNA2 SOD1 HTT	2.46e-03	289	95	5	C0011581
Disease	Lymphoma, T-Cell, Cutaneous	NFKB2 FGFR3	2.48e-03	23	95	2	C0079773
Disease	venous thromboembolism, tissue plasminogen activator measurement	VWF DGKZ	2.48e-03	23	95	2	EFO_0004286, EFO_0004791
Disease	Weight decreased	IFNA2 SOD1	2.48e-03	23	95	2	C1262477
Disease	Autism Spectrum Disorders	EPHX2 DIP2A GTF2I	2.64e-03	85	95	3	C1510586
Disease	visceral adipose tissue measurement, body mass index	PCDHAC2 PCDHA8 PCDHA7	2.82e-03	87	95	3	EFO_0004340, EFO_0004765
Disease	Fatty Liver	IFNA2 GPD1L SOD1	2.91e-03	88	95	3	C0015695
Disease	Steatohepatitis	IFNA2 GPD1L SOD1	2.91e-03	88	95	3	C2711227
Disease	lysophosphatidylethanolamine 16:0 measurement	GRIA1 SORCS3	3.17e-03	26	95	2	EFO_0010366

Protein segments in the cluster

Peptide	Gene	Start	Entry
MIKAGVAGCREPQFI	ACTRT3	16	Q9BYD9
DCGMILPQDKVIIAE	ATP13A3	761	Q9H7F0
PHGCVLVMGNIIDCK	GOT1L1	176	Q8NHS2
LVMGNIIDCKLTPSG	GOT1L1	181	Q8NHS2
HLVAGCVLIKQPEGM	CCDC171	576	Q6TFL3
FKEGIGMLVCTGEPQ	CCDC171	831	Q6TFL3
AMEGLKGGPEVVACQ	CCDC171	1186	Q6TFL3
KGGPEVVACQAMIKS	CCDC171	1191	Q6TFL3
GAPLVVICQGKIMLE	DPYSL3	441	Q14195
CQRGSEIVAGLEKMP	GRN	416	P28799
VCFNMEIIGGKEVSP	GZMK	21	P49863
KGMGVCLFNLPEVRE	ADAM12	406	O43184
AVCMGAINEKTKGPL	AQP8	171	O94778
EGSGCAKVQVLKPLM	ARMCX6	246	Q7L4S7
APGVGKTQLCMQLAV	RAD51C	126	O43502
ICGKEIEVMGVISPD	RAD54B	186	Q9Y620
TEDVPMILVGNKCDL	RAP1A	106	P62834
AEKPDIMLGVVCGAL	ACACB	766	O00763
NCMKVIKANGRGDPV	FBXW10B	646	O95170
QRVCSGEGPPKTDLM	PCDHA7	756	Q9UN72
VGPKICLEDNVLMSG	FAM3C	81	Q92520
ALVCGVPAMDIPQTK	PAEP	11	P09466
QRVCSGEGPPKTDLM	PCDHA8	756	Q9Y5H6
VLPLQGCGLMEGKTT	IGDCC3	751	Q8IVU1
LGGNVEMKIQSPCVF	MAP10	636	Q9P2G4
LGKNVVGRMPDCSVA	MDC1	51	Q14676
LGLVMKERCQTAGNP	DOLK	91	Q9UPQ8
MVEGPGCTLNGEKIR	NEIL3	1	Q8TAT5
GCMGVDKVAGPEVLE	NEK9	456	Q8TD19
MAAAPLKVCIVGSGN	GPD1L	1	Q8N335
RPQAVQGGKALMCVL	MTIF3	226	Q9H2K0
GSVMAIERCIGVTKP	PTGFR	126	P43088
GDGIVLCKMINLSVP	PLS3	161	P13797
VVAMIGDGPCVVKTL	PLXNB1	1416	O43157
CVTVPKMLGDFLQQG	OR4Q3	76	Q8NH05
VRCIIPNETKTPGAM	MYH2	676	Q9UKX2
KMFELGECVTGTIGP	KIF21B	1481	O75037
ECEVILMVGLPGSGK	HNRNPUL2	451	Q1KMD3
SRAPCKVQGLEGIKM	NEK8	601	Q86SG6
KECRAVVIAGGTMQP	DDX11	611	Q96FC9
GQFGEVKECLVMRDP	MSI1	41	O43347
IKNIFGDMLCPRGEV	PLCXD1	171	Q9NUJ7
PIGLNCKELTGDTVM	HFM1	356	A2PYH4
GPVPMAGHCKVLVDI	PCDHAC2	341	Q9Y5I4
PVMRKICQVVPAGLA	PAQR8	206	Q8TEZ7
IPFGIGKRVCMGEQL	CYP2U1	481	Q7Z449
PGVKLVIEAVCIMKG	DNAH1	2946	Q9P2D7
GIPKIIQLCDGIMAS	HTT	1516	P42858
IESCQVGMVKPEPQI	EPHX2	151	P34913
IKMVENRDTGCQIGP	CPLANE1	1806	Q9H799
VESIPIMLVGNKCDE	DIRAS2	111	Q96HU8
TRQVVCDLGNPMKAG	ITGAV	706	P06756
PTVAPDCVIGKDKQM	FAM131C	36	Q96AQ9
GTPMLLDGVKCVGAE	C20orf27	146	Q9GZN8
ICMPKVGEVITGGQR	DNAAF11	376	Q86X45
CVIQGVGVTETPLMK	IFNA2	121	P01563
ECELGNPMKRGAQVT	ITGA7	791	Q13683
TGVPDGIMQFIKLCT	ERCC3	146	P19447
VVCDGMDLTPKIQDL	DGKZ	506	Q13574
QVMPGANVCVVKLEG	DIP2A	721	Q14689
VVNVRGLMCQGPEKV	FLRT1	321	Q9NZU1
KPLGEGCFGQVVMAE	FGFR3	476	P22607
IEQRKPCDTMKVGGN	GRIA1	726	P42261
KITINPGCVVVDGMP	GTF2I	896	P78347
PVIQAGMEALKAAEC	SEC24C	621	P53992
FDGEGKVRMIVCVNP	KIF23	401	Q02241
IFGESIMIGVKPCID	NUP35	231	Q8NFH5
FIPGLKVDGMDVLCV	PDHA2	246	P29803
AMAGQRVELPCKALG	DSCAM	236	O60469
AEPVSLMCNVKGTPL	DSCAM	421	O60469
PVQPGMLIDVCKYLG	TRIM35	271	Q9UPQ4
VCDAQVDLPMGGVKA	TRIM45	96	Q9H8W5
RAIKNAIEDGCMVPG	CCT6B	396	Q92526
CNASGTEKMRPLIVG	TIGD6	216	Q17RP2
IIPTVGKGIMEGNCV	RBL1	71	P28749
LLNQGEPCVMGERKI	SORCS3	706	Q9UPU3
KGVCVRLSMGPCIVE	SLC9B2	201	Q86UD5
VAKAVGGLMIPVFCV	SATB2	51	Q9UPW6
ELECVNGDLKSVPMI	RXFP2	121	Q8WXD0
LNCVVGSQGMPKRIV	TCP1	216	P17987
VRCIIPNETKTPGAM	MYH3	671	P11055
AKPQECLMGTVGTLL	IARS1	1181	P41252
MGCQDILENVPGRSK	PKN2	336	Q16513
DIPAKLIVCGMTSNG	RO60	491	P10155
MATKAVCVLKGDGPV	SOD1	1	P00441
PKVLVGLCIVGCVMD	WFDC3	171	Q8IUB2
MVNVLKGVLIECDPA	GTF2H5	1	Q6ZYL4
KSPCVEEEQSRGMGV	TTBK1	416	Q5TCY1
ACMLNGTVIGPGKTV	VWF	2581	P04275
GTVIGPGKTVMIDVC	VWF	2586	P04275
GIAPICVMAKRKNGT	ERVFRD-1	121	P60508
MFVKLVNPCSGEGAI	RNASEH2B	36	Q5TBB1
MPSVAEGVKLGIQEC	WNT3	66	P56703
VIFCPEPGQKLMGIV	POLR1F	121	Q3B726
QPESLCIVEMGGTEK	SF3B3	636	Q15393
DIIVDPMCGTGAIPI	THUMPD3	321	Q9BV44
SNCKEPGIAGLMKIV	THYN1	116	Q9P016
PGKVVMVAICINGLN	SLC30A9	236	Q6PML9
GGCAAQSKDIIPLVM	SCN11A	871	Q9UI33
GACTKQGGPLMVIVE	FLT1	896	P17948
IGGNRLKQPPECMED	TYRO3	746	Q06418
KEVPQMCIPGKIEEV	AGL	761	P35573
GDVVTVACEAKGEPM	MXRA5	2361	Q9NR99
GICTVTAGPKDMVVG	NFKB1	121	P19838
ELGICAVSVGPKDMT	NFKB2	116	Q00653