Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessepithelial cilium movement involved in extracellular fluid movement

ROPN1L CFAP54 MEGF8 SPAG17 DNAAF1

1.57e-05591105GO:0003351
GeneOntologyBiologicalProcessextracellular transport

ROPN1L CFAP54 MEGF8 SPAG17 DNAAF1

2.00e-05621105GO:0006858
DomainDppa2/4_C_dom

DPPA2 DPPA4

3.63e-0521132IPR025891
DomainDppa2/4_central_dom

DPPA2 DPPA4

3.63e-0521132IPR025892
DomainTMEM183

TMEM183A TMEM183BP

3.63e-0521132IPR026509
DomainDppa2_A

DPPA2 DPPA4

3.63e-0521132PF14049
DomainDCR

DPPA2 DPPA4

3.63e-0521132PF14047
Domain-

RASA4 RASA4B

1.08e-04311324.10.1130.10
DomainL_dom-like

NLRP12 ERBB4 TLR7 LRRK1 SKP2 LRRIQ1 LRRC31 NLRC5 DNAAF1

1.72e-043281139IPR032675
DomainLeu-rich_rpt

NLRP12 TLR7 LRRK1 SKP2 LRRIQ1 LRRC31 NLRC5 DNAAF1

2.44e-042711138IPR001611
DomainLRR_1

TLR7 LRRK1 SKP2 LRRIQ1 LRRC31 NLRC5 DNAAF1

3.74e-042191137PF00560
Domain-

DNHD1 ABCC1 NLRP12 DNAH10 MYO7B ZGRF1 WRN IFI44 CHD9 LRRK1 RHOH TRANK1 NLRC5

5.76e-04746113133.40.50.300
DomainP-loop_NTPase

DNHD1 ABCC1 NLRP12 DNAH10 MYO7B ZGRF1 WRN IFI44 CHD9 LRRK1 RHOH TRANK1 LRRIQ1 NLRC5

5.99e-0484811314IPR027417
Domain-

NLRP12 TLR7 LRRK1 SKP2 LRRIQ1 LRRC31 NLRC5 DNAAF1

7.48e-0432111383.80.10.10
DomainIQ

MYO7B UBE3B LRRIQ1 SCN3A

9.04e-04711134PF00612
DomainBTK

RASA4 RASA4B

1.27e-0391132SM00107
DomainZnf_Btk_motif

RASA4 RASA4B

1.27e-0391132IPR001562
DomainBTK

RASA4 RASA4B

1.27e-0391132PF00779
DomainZF_BTK

RASA4 RASA4B

1.27e-0391132PS51113
DomainLRR

NLRP12 TLR7 LRRK1 LRRIQ1 NLRC5 DNAAF1

1.40e-032011136PS51450
DomainIQ

MYO7B UBE3B LRRIQ1 SCN3A

1.48e-03811134SM00015
DomainIQ_motif_EF-hand-BS

MYO7B UBE3B LRRIQ1 SCN3A

2.18e-03901134IPR000048
DomainWD40_repeat_dom

TAF1C EML6 LRRK1 RACK1 MIOS DCAF4L1 WDR62

2.20e-032971137IPR017986
DomainIQ

MYO7B UBE3B LRRIQ1 SCN3A

2.45e-03931134PS50096
DomainRasGAP

RASA4 RASA4B

3.15e-03141132SM00323
DomainDynein_HC_stalk

DNHD1 DNAH10

3.15e-03141132IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH10

3.15e-03141132IPR013602
DomainDHC_N2

DNHD1 DNAH10

3.15e-03141132PF08393
DomainMT

DNHD1 DNAH10

3.15e-03141132PF12777
DomainRasGAP_CS

RASA4 RASA4B

3.15e-03141132IPR023152
DomainDHC_fam

DNHD1 DNAH10

3.62e-03151132IPR026983
DomainRasGAP

RASA4 RASA4B

3.62e-03151132PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

3.62e-03151132PS00509
DomainDynein_heavy

DNHD1 DNAH10

3.62e-03151132PF03028
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

3.62e-03151132PS50018
DomainDynein_heavy_dom

DNHD1 DNAH10

3.62e-03151132IPR004273
Domain-

RASA4 RASA4B

4.12e-031611321.10.506.10
Domain-

TAF1C EML6 RACK1 MIOS DCAF4L1 PLXNA2 WDR62

4.14e-0333311372.130.10.10
DomainWD40/YVTN_repeat-like_dom

TAF1C EML6 RACK1 MIOS DCAF4L1 PLXNA2 WDR62

4.28e-033351137IPR015943
DomainLRR_6

NLRP12 LRRC31 NLRC5

4.50e-03551133PF13516
DomainRasGAP_dom

RASA4 RASA4B

5.21e-03181132IPR001936
DomainLeu-rich_rpt_Cys-con_subtyp

SKP2 NLRC5

5.80e-03191132IPR006553
DomainLRR_CC

SKP2 NLRC5

5.80e-03191132SM00367
Pubmed

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

USP34 HUWE1 FANCI

4.16e-0610115317478428
Pubmed

Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency.

DPPA2 DPPA4

1.08e-052115230146411
Pubmed

Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.

TMEM183A TMEM183BP

1.08e-052115216644869
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

1.08e-052115211448776
Pubmed

Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.

DPPA2 DPPA4

1.08e-052115223963736
Pubmed

Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region.

DPPA2 DPPA4

1.08e-052115233316032
Pubmed

TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter.

TAF1C UBTF

1.08e-052115215970593
Pubmed

Enhanced PKC beta II translocation and PKC beta II-RACK1 interactions in PKC epsilon-induced heart failure: a role for RACK1.

RACK1 PRKCE

1.08e-052115211709417
Pubmed

DPPA2 and DPPA4 are necessary to establish a 2C-like state in mouse embryonic stem cells.

DPPA2 DPPA4

1.08e-052115230948459
Pubmed

Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program.

DPPA2 DPPA4

1.08e-052115230692203
Pubmed

Dppa2 and Dppa4 safeguard bivalent chromatin in order to establish a pluripotent epigenome.

DPPA2 DPPA4

1.08e-052115232572253
Pubmed

Dppa2 and Dppa4 counteract de novo methylation to establish a permissive epigenome for development.

DPPA2 DPPA4

1.08e-052115232572256
Pubmed

Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi-lineage commitment.

DPPA2 DPPA4

1.08e-052115232572255
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

1.08e-052115216041389
Pubmed

Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage.

WRN POLL

1.08e-052115222753033
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 SYNRG ARHGEF19 RAPGEF6 UBE3B MED14 LRRK1 HUWE1 CNPPD1 MEGF8 FANCI NLRC5 POLL CAMSAP1

1.78e-0511051151435748872
Pubmed

Mitotic arrest in teratoma susceptible fetal male germ cells.

DPPA2 PIWIL2 DPPA4

1.91e-0516115321674058
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

FN1 HUWE1 TRMT61B CAMSAP1 WDR62

2.81e-05106115531024071
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

PAPPA2 USP34 FN1 ZGRF1 MED14 FANCI POP1 DCAF4L1

2.92e-05363115814691545
Pubmed

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.

HUWE1 POLL

3.24e-053115222203964
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

3.24e-053115225637021
Pubmed

Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem.

HUWE1 POLL

3.24e-053115222370481
Pubmed

Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.

DPPA4 TRIM38 PLXNA2

5.18e-0522115321348951
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

USP34 RAPGEF6 TMEM183A FN1 DHDDS TMEM183BP HUWE1 RHOH RACK1 UBTF POP1 LTN1 NCKAP1L

6.32e-0510841151311544199
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 FN1 HUWE1 NUP205 RBM25 RACK1 FANCI UBTF SYNE2 POP1

6.47e-056531151022586326
Pubmed

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

RASA4 RASA4B

6.48e-054115221460216
Pubmed

Potential involvement of kallikrein hK2 in the hydrolysis of the human seminal vesicle proteins after ejaculation.

FN1 KLK2

6.48e-05411529016396
Pubmed

The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF.

TAF1C UBTF

6.48e-054115212498690
Pubmed

The anchoring protein RACK1 links protein kinase Cepsilon to integrin beta chains. Requirements for adhesion and motility.

RACK1 PRKCE

6.48e-054115211934885
Pubmed

Protein kinase C epsilon-dependent regulation of cystic fibrosis transmembrane regulator involves binding to a receptor for activated C kinase (RACK1) and RACK1 binding to Na+/H+ exchange regulatory factor.

RACK1 PRKCE

6.48e-054115211956211
Pubmed

Regulation of p27 (Kip1) by Ubiquitin E3 Ligase RNF6.

UBE2C SKP2

6.48e-054115235456636
Pubmed

Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis.

FN1 RACK1

6.48e-054115222378065
Pubmed

Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.

RASA4 RASA4B

6.48e-054115216234249
Pubmed

Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms.

WRN RACK1

6.48e-054115219966859
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 RAPGEF6 ZGRF1 HUWE1 SETDB1 CAMSAP1 ZMYM5 WDR62

7.86e-05418115834709266
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP34 ABCC1 NCAPD3 THOC7 TMEM183A FAM98B HUWE1 SKP2 NUP205 FANCI UBTF SYNE2 POP1 LTN1 TRMT61B

8.25e-0514401151530833792
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 ERBB4 PHLDA1 TAF1C CHD9 ADCY6 FCSK SETDB1 RBM25 RACK1 LTN1 LZTS2 WDR62

8.46e-0511161151331753913
Pubmed

Repression of RNA polymerase I transcription by the tumor suppressor p53.

TAF1C UBTF

1.08e-045115210913176
Pubmed

Dppa2 and Dppa4 are closely linked SAP motif genes restricted to pluripotent cells and the germ line.

DPPA2 DPPA4

1.08e-045115216990585
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

MED14 HUWE1 NUP205 SETDB1 UBTF POP1 MIOS CAMSAP1

1.12e-04440115834244565
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 MYO7B ZGRF1 UBTF POP1 CAMSAP1

1.33e-04234115636243803
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

USP34 NCAPD3 THOC7 PHLDA1 WRN MED14 FAM98B FANCI

1.37e-04453115829656893
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SYNRG ERBB4 RAPGEF6 MEGF8 SYNE2 OSBPL6 AGFG1 PRKCE CAMSAP1 RNF180 WDR62

1.38e-048611151136931259
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

USP34 SYNRG THOC7 ZGRF1 UBE2C HUWE1 SETDB1 AGFG1 LZTS2

1.53e-04588115938580884
Pubmed

Functional proteomics mapping of a human signaling pathway.

PAPPA2 FN1 FAM161B HUWE1 PHKA2 SETDB1 LZTS2 CAMSAP1 ZMYM5

1.58e-04591115915231748
Pubmed

A novel zinc finger protein interacts with receptor-interacting protein (RIP) and inhibits tumor necrosis factor (TNF)- and IL1-induced NF-kappa B activation.

AGFG1 TRIM38

1.61e-046115211854271
Pubmed

DPPA2 and DPPA4 are dispensable for mouse zygotic genome activation and pre-implantation development.

DPPA2 DPPA4

1.61e-046115234878123
Pubmed

Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription.

TAF1C UBTF

1.61e-046115211698641
Pubmed

Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study.

DPPA2 DPPA4

1.61e-046115223761726
Pubmed

Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.

ERBB4 FN1 ADAMTS15

1.63e-0432115331434798
Pubmed

Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival.

DPPA2 DPPA4

2.25e-047115234931676
Pubmed

A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription.

TAF1C UBTF

2.25e-047115217318177
Pubmed

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I.

TAF1C UBTF

2.25e-047115215723054
Pubmed

Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.

RASA4 RASA4B

3.00e-048115210810084
Pubmed

Analysis of the sperm flagellar axoneme using gene-modified mice.

CFAP54 SPAG17

3.00e-048115232554934
Pubmed

hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters.

TAF1C UBTF

3.00e-048115211250903
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

WRN PIGV MEGF8 WDR62

3.48e-04100115425807483
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

USP34 NCAPD3 MRPL37 DPPA2 HUWE1 DPPA4 FANCI

3.59e-04396115726687479
Pubmed

Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

NCAPD3 SETDB1 POP1

3.68e-044211537584044
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

ABCC1 NCAPD3 FANCI LTN1

4.04e-04104115431240132
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

LRRK1 LRRIQ1 FANCI LZTS2

4.50e-04107115411347906
Pubmed

Essential roles of ECAT15-2/Dppa2 in functional lung development.

DPPA2 DPPA4

4.79e-0410115221896782
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

USP34 ERBB4 EML6 LRRK1 RYK RBM25 RASA4B

5.10e-04420115728065597
Pubmed

The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development.

LZTS1 LZTS2

5.85e-0411115221949185
Pubmed

Expression profile of protein kinase C isozymes in preimplantation mouse development.

RACK1 PRKCE

5.85e-0411115216183862
Pubmed

Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling.

CLEC7A TLR7

5.85e-0411115221282509
Pubmed

Maternal DCAF13 Regulates Chromatin Tightness to Contribute to Embryonic Development.

DPPA4 UBTF

5.85e-0411115231000741
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ERBB4 RAPGEF6 CCDC141 DPPA4 AGFG1 CAMSAP1 ZMYM5

5.86e-04430115735044719
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

USP34 FAM98B HUWE1 NUP205 PHKA2 RACK1 FANCI LZTS2

6.40e-04571115837167062
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

SYNRG RAPGEF6 LZTS2 CAMSAP1 WDR62

6.71e-04209115536779422
Pubmed

Conservation and reorganization of loci on the mammalian X chromosome: a molecular framework for the identification of homologous subchromosomal regions in man and mouse.

ATP7A PHKA2

7.00e-041211522899541
Pubmed

Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.

TAF1C UBTF

8.26e-0413115215226435
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

NCAPD3 WRN CHD9 FANCI UBTF

8.80e-04222115537071664
Pubmed

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

MRPL37 NUP205 RACK1 TRIM38

9.09e-04129115428973437
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

NCAPD3 MRPL37 HUWE1 FCSK FANCI LZTS2 TRMT61B WDR62

9.39e-04606115836538041
Pubmed

Recognition of fungal RNA by TLR7 has a nonredundant role in host defense against experimental candidiasis.

CLEC7A TLR7

9.61e-0414115222777843
Pubmed

Recognition of yeast nucleic acids triggers a host-protective type I interferon response.

CLEC7A TLR7

9.61e-0414115221480215
Pubmed

Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages.

PIWIL2 DPPA4

9.61e-0414115221056461
Pubmed

Intrinsically Disordered Protein TEX264 Mediates ER-phagy.

SYNRG DHDDS RBM25 ATG4B

9.62e-04131115431006538
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SYNRG NCAPD3 RAPGEF6 MED14 HUWE1 ADCY6 RBM25 POP1 WDR62

1.10e-03774115915302935
Pubmed

E3-independent monoubiquitination of ubiquitin-binding proteins.

UBE2C POLL

1.11e-0315115217588522
Pubmed

SCF-mediated Cdh1 degradation defines a negative feedback system that coordinates cell-cycle progression.

UBE2C SKP2

1.11e-0315115223972993
Pubmed

LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.

ABCC1 SLC47A1

1.11e-0315115228112518
Pubmed

Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects.

MAP3K12 CAMSAP1

1.26e-0316115236092713
Pubmed

Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.

CLEC7A TLR7

1.26e-0316115229576482
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

DNHD1 ERBB4 SKP2 FANCI SYNE2 LTN1

1.34e-03363115625036637
Pubmed

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

UBE3B HUWE1 LTN1

1.38e-0366115324811749
Pubmed

Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.

SKP2 MAP3K12

1.43e-0317115219398581
Pubmed

Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos.

DPPA2 DPPA4

1.43e-0317115231315026
Pubmed

Maternal UHRF1 Is Essential for Transcription Landscapes and Repression of Repetitive Elements During the Maternal-to-Zygotic Transition.

DPPA2 DPPA4

1.43e-0317115233634103
Pubmed

Jun and JunD-dependent functions in cell proliferation and stress response.

ERBB4 GCLM

1.43e-0317115220300111
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

ABCC1 SLC47A1

1.60e-0318115231791063
Pubmed

The proto-oncogene Ret is required for male foetal germ cell survival.

PIWIL2 DPPA4

1.60e-0318115222360967
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

USP34 PHKA2 RACK1 LZTS1 WDR62

1.68e-03257115530945288
Pubmed

EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.

FAM98B FANCI

1.79e-0319115218445686
Pubmed

Rrn3 becomes inactivated in the process of ribosomal DNA transcription.

TAF1C UBTF

1.79e-0319115212646563
Pubmed

Impact of ancestry and common genetic variants on QT interval in African Americans.

OSBPL6 PRKCE

1.79e-0319115223166209
Pubmed

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.

TRIM42 EML6

1.79e-0319115225367360
Pubmed

Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort.

SFR1 LZTS1

1.79e-0319115223551011
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

USP34 NUP205 SETDB1 RASA4B ZMYM5

1.83e-03262115536880596
GeneFamilyLeucine zipper tumor suppressor family

LZTS1 LZTS2

9.08e-0547121314
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

6.70e-0410712830
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

ERBB4 DNAH10 ROPN1L CFAP54 LRRIQ1 SYNE2 OSBPL6 ADGRF5 SPAG17 DNAAF1

9.32e-1119511510fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

ERBB4 DNAH10 ROPN1L CFAP54 LRRIQ1 SYNE2 OSBPL6 ADGRF5 SPAG17 DNAAF1

9.32e-1119511510eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 ADGRF5 SPAG17 DNAAF1

3.96e-081931158bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

DNAH10 ROPN1L CFAP54 LRRIQ1 SYNE2 OSBPL6 SPAG17 DNAAF1

4.29e-08195115821dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1 TCTN1

4.64e-0819711586865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1 TCTN1

5.22e-082001158cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1 TCTN1

5.22e-082001158873def69bf55ccbfc944bc10c5afc06be019c312
ToppCellCiliated_cells-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

3.82e-0717611571c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

4.44e-071801157bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

5.34e-071851157f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GPR34 CLEC7A EVI2B LIPN TLR7 RHOH NCKAP1L

5.54e-071861157fc6e591089c87a66653c8e552be9c0fe0c82ecd5
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR34 CLEC7A EVI2B TLR7 LRRK1 RHOH NCKAP1L

5.95e-0718811578fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

6.39e-071901157169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

6.39e-0719011570cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

7.10e-071931157e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

7.35e-071941157756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR34 IFI44 CLEC7A EVI2B TLR7 TRIM38 NCKAP1L

7.61e-071951157b6bf75669f267ecdc96818c7022db852e37a9fe1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPR34 CLEC7A TLR7 LRRK1 CCDC141 RHOH NCKAP1L

7.61e-071951157ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1 TCTN1

7.88e-071961157de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1 TCTN1

7.88e-071961157d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1 TCTN1

8.15e-07197115771fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CFAP54 LRRIQ1 SYNE2 OSBPL6 SPAG17 DNAAF1

8.15e-07197115774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1 TCTN1

8.15e-071971157e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1 TCTN1

8.15e-071971157d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.02e-0720011579ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1 TCTN1

9.02e-07200115779e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.02e-072001157bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.02e-072001157ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.02e-072001157a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.02e-072001157918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THOC7 PHLDA1 DPPA2 ELMO3 LRRIQ1 TCTN1

2.13e-061451156186b8bd8ac2d5c66cc29fdc2dd6751eddce3e8b8
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

2.40e-061481156d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

2.40e-061481156c8e93b87212f55774223caa385859c566fa1981f
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

2.49e-0614911566399c5a2f06d79f020dece252526f1c0c110d569
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

2.69e-0615111568216462e723fec2797387929dde095370947e10a
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

2.69e-06151115681cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

2.69e-0615111569cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

3.02e-0615411564e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 EML6 CFAP54 LRRIQ1 SPAG17 DNAAF1

3.02e-0615411569ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

3.02e-0615411567556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 EML6 CFAP54 LRRIQ1 SPAG17 DNAAF1

3.02e-06154115658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

3.13e-0615511565f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

3.13e-0615511560944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

DNAH10 CCDC141 LRRIQ1 SYNE2 SPAG17 RNF180

3.25e-06156115610d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Fos_(Layer_5a,_IEG+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NLRP12 AVPR1B PIWIL2 DNAAF1

3.45e-06401154b4c04100180790e1a53a15e8311e40015306c088
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 TLR7 LRRK1 PKHD1L1 RHOH DNAAF1

4.04e-061621156ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 TLR7 LRRK1 PKHD1L1 RHOH DNAAF1

4.04e-0616211569e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 CLEC7A TLR7 SKP2 RNF180 NCKAP1L

4.98e-0616811564ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC1 CLEC7A TLR7 SKP2 RNF180 NCKAP1L

5.15e-061691156454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

5.15e-061691156fba841664939c771881ba97f14ef1df6635c04ff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UBE2C CLEC7A CCDC141 FANCI WDR62 NCKAP1L

5.15e-06169115654b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCellNS-critical-d_07-13-Lymphoid-B_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GPR34 TLR7 CCDC141 RHOH RACK1 SCN3A

6.72e-061771156d4db058c09012ec9fbde61277a9f86d9956de8fc
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

6.72e-061771156c38138fb5ad9766c2d240811210c854338cd612e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

6.94e-061781156de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellnormal_Pleural_Fluid-Myeloid_cells-mo-Mac|normal_Pleural_Fluid / Location, Cell class and cell subclass

FN1 GPR34 CLEC7A C22orf31 SLC47A1 DNAAF1

7.16e-061791156cd3c58e044f5a38e815313a1636153d81a592fce
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 AVPR1B ZGRF1 UBE2C FANCI WDR62

7.16e-06179115680112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

7.63e-061811156dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

7.88e-0618211567ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

7.88e-061821156fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L LRRIQ1 OSBPL6 SPAG17 DNAAF1

7.88e-061821156e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

IFI44 CHD9 TRANK1 SYNE2 NLRC5 TRIM38

8.13e-0618311568f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

8.38e-0618411565daff849625f2f41d56615569c0ed59cd733b34c
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERBB4 DNAH10 CFAP54 LRRIQ1 SPAG17 DNAAF1

8.65e-0618511565e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ROPN1L CFAP54 LRRIQ1 OSBPL6 SPAG17 DNAAF1

8.65e-061851156d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

8.65e-06185115630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

8.65e-0618511563e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

8.65e-06185115618a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

8.92e-061861156f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GPR34 CLEC7A EVI2B TLR7 RHOH NCKAP1L

8.92e-0618611566575ec6a626cdea169ffd185d47828dfaa29475d
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.19e-0618711562b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.19e-061871156f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.19e-0618711569e10ed56090d82589bc457788282f664b70ace4b
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

DNAH10 ROPN1L LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.19e-0618711561a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.19e-061871156bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR34 CLEC7A EVI2B TLR7 TRIM38 NCKAP1L

9.48e-06188115626c0a94951236a5d17a169920b0a8a9d0dd7d0ed
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR34 CLEC7A EVI2B TLR7 TRIM38 NCKAP1L

9.48e-061881156af300574c4e95505f56bf716bcee1e4777944e8e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR34 CLEC7A EVI2B TLR7 TRIM38 NCKAP1L

9.48e-061881156e169e9bb85892e52880ee949d0f691d0ea0c8dc9
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.48e-06188115661a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAH10 ROPN1L LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.48e-061881156803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.48e-06188115634b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.48e-0618811562b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.77e-061891156a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 ROPN1L LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.77e-06189115657ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 ROPN1L LRRIQ1 OSBPL6 SPAG17 DNAAF1

9.77e-061891156ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.77e-06189115668a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.77e-061891156dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.77e-061891156b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.77e-06189115627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.77e-0618911563e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCiliated|World / shred by cell class for parenchyma

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

9.77e-061891156711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

1.01e-0519011569ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

1.01e-051901156833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPR34 CLEC7A TLR7 LRRK1 CCDC141 NCKAP1L

1.01e-051901156788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

1.01e-0519011567031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

1.01e-051901156a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L LRRIQ1 OSBPL6 SPAG17 DNAAF1

1.01e-051901156cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DNAH10 ROPN1L CFAP54 LRRIQ1 SPAG17 DNAAF1

1.01e-051901156426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GPR34 CLEC7A EVI2B TLR7 RHOH NCKAP1L

1.01e-0519011565e0e4a48159ec05ba1b599752b769a7b4da08588
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 ROPN1L LRRIQ1 OSBPL6 SPAG17 DNAAF1

1.04e-0519111567b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPR34 CLEC7A TLR7 LRRK1 CCDC141 NCKAP1L

1.04e-051911156baa70781633a3fe5bf987f9d8dff3884f5167e7f
Diseasearf-GAP domain and FG repeat-containing protein 1 measurement

NLRP12 AGFG1

8.37e-0541112EFO_0803312
Diseasemitral valve annular diameter

ERBB4 CCDC141

2.08e-0461112EFO_0020096
Diseasemyeloid white cell count

USP34 THOC7 FN1 DNAH10 EML6 DHDDS LRRK1 PIGV NLRC5 PRKCE ADGRF5 SPAG17

2.17e-0493711112EFO_0007988
DiseaseParoxysmal atrial fibrillation

USP34 ERBB4 DNAH10 PHLDA1 SYNE2

3.16e-041561115C0235480
Diseasefamilial atrial fibrillation

USP34 ERBB4 DNAH10 PHLDA1 SYNE2

3.16e-041561115C3468561
DiseasePersistent atrial fibrillation

USP34 ERBB4 DNAH10 PHLDA1 SYNE2

3.16e-041561115C2585653
DiseaseAtrial Fibrillation

USP34 ERBB4 DNAH10 PHLDA1 SYNE2

3.55e-041601115C0004238
Diseasepro‐interleukin‐16 measurement

NLRP12 ADAMTSL3

7.54e-04111112EFO_0010629
Diseaseiron deficiency anemia (biomarker_via_orthology)

ATP7A FN1

1.06e-03131112DOID:11758 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

ABCC1 FN1 WRN ADAMTSL3 CNPPD1 ADAMTS15 PRKCE LZTS2 SPAG17

1.36e-037021119C0009402
Diseaseidiopathic scoliosis (implicated_via_orthology)

DNAH10 DNAAF1

1.63e-03161112DOID:0060250 (implicated_via_orthology)
Diseaseresponse to hydrochlorothiazide, systolic blood pressure change measurement

TAF1C DNAAF1

1.63e-03161112EFO_0005202, EFO_0006944
Diseasetriiodothyronine measurement

ERBB4 PRKCE

1.63e-03161112EFO_0008392
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD3 WDR62

1.63e-03161112DOID:0070296 (is_implicated_in)
Diseasepulse pressure measurement

PAPPA2 USP34 FN1 ADAMTSL3 CCDC141 RYK DIRC1 FCSK RBM25 TRANK1 MEGF8 ADAMTS15 PRKCE

2.22e-03139211113EFO_0005763
Diseasemitochondrial heteroplasmy measurement

DHDDS NUP205 LZTS2

2.27e-03691113EFO_0600008
Diseasealpha-tocopherol measurement

SCN3A PRKCE

2.55e-03201112EFO_0007898
Diseasenucleotide measurement

SYNE2 PRKCE PLXNA2

2.66e-03731113EFO_0010513
DiseaseAutosomal Recessive Primary Microcephaly

NCAPD3 WDR62

3.08e-03221112C3711387
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

IFI44 HAPLN4

3.08e-03221112EFO_0009312
DiseaseAntihypertensive use measurement

UBE3B PDE10A CCDC141 RYK PRKCE

3.33e-032651115EFO_0009927

Protein segments in the cluster

PeptideGeneStartEntry
GSQLLLNWCVQIAKG

ERBB4

816

Q15303
SLWFKIQRACINEKG

EDDM3A

71

Q14507
ALGRWQLLRKCLQAL

C1orf167

536

Q5SNV9
MFLWQKCKLGIQRLN

CFAP54

611

Q96N23
WKQLGANVLLFLCTN

ADCY6

286

O43306
QTGNLLNWGRLRKKC

GCLM

21

P48507
NQNKWTLGVILCKVV

GPR34

116

Q9UPC5
AWCQQLKLSSKGQKL

DPPA4

101

Q7L190
KAIKQKLWEALCSQG

C22orf31

241

O95567
KSFTCWKKNVRLQGL

DNHD1

371

Q96M86
RAKIAANLQWICAKA

CAMSAP1

36

Q5T5Y3
DWCQQVKKLSLLGGA

ATG4B

331

Q9Y4P1
ALTLRNFCAWQKKLN

ADAMTS15

286

Q8TE58
CKVTNIEGLLHKNNW

ATP7A

1121

Q04656
GAQLVKSAWLSLCLQ

POLL

106

Q9UGP5
KCVNELNQWLSALRK

RASA4

656

O43374
LLAKCGLVLSWKRVQ

RBM25

106

P49756
VWNLANCKLKTNHIG

RACK1

176

P63244
KCVNELNQWLSALRK

RASA4B

656

C9J798
WDGKRCIANSLKALI

NUP205

136

Q92621
FLICKLKNTWLSGVN

LTN1

866

O94822
CLGAQDKQWLFSKLP

ARHGEF19

411

Q8IW93
CKKQLINTLCSGRWD

FANCI

156

Q9NVI1
CLKKNSQVWLGRHNL

KLK2

66

P20151
TKWCQRKLQAELKIG

KIAA0100

31

Q14667
IASTKICNNKILWLI

LIPN

241

Q5VXI9
WEVCQKSGEISLLKQ

LZTS2

441

Q9BRK4
QWEVCQKSGEISLLK

LZTS1

381

Q9Y250
QEKWTCRQLKTLDLS

LRRK1

491

Q38SD2
SLLWGLLRQGLQCKV

PRKCE

261

Q02156
KVKSLCWASLNQLDS

DCAF4L1

126

Q3SXM0
LELNWLLGKDVQCTK

PLXNA2

381

O75051
LLKACRDNLSQWEKV

PDE10A

741

Q9Y233
INVQKLKAKLSSWCI

PEX2

211

P28328
KCLRKPVLNDQNWAG

EVI2B

226

P34910
LSWNKCVGGNLKLLL

LRRC31

401

Q6UY01
CVLLWKAKQALDQRQ

MEGF8

2666

Q7Z7M0
LNSNSQCQKLWKLCL

NCKAP1L

271

P55160
QCQKLWKLCLQGSLY

NCKAP1L

276

P55160
LQELKQKGRWCLLES

FAM161B

71

Q96MY7
CRLLEGVKQALWLTK

MRPL37

111

Q9BZE1
LELQQIKTWNIGKCE

HUWE1

36

Q7Z6Z7
LWNILRNNIGKDLSK

OSBPL6

571

Q9BZF3
WNCGLESLKNLQQLI

LRRIQ1

961

Q96JM4
SWKNLILKVCQGCIS

NEK3

206

P51956
LQLGNKNLWSCLVRL

NLRC5

6

Q86WI3
LKFWLGQQRCKQSIK

MED14

496

O60244
LRSRKLLKQLSAWCG

POP1

806

Q99575
RNKLLKIQCLEGGIW

PAPPA2

1571

Q9BXP8
ILCTKEGLWTQEFKL

PAPPA2

1631

Q9BXP8
LLGQCLTSYWEQKKL

FCSK

981

Q8N0W3
TWQLALGSLCQRLVK

CNPPD1

216

Q9BV87
NRLDSICQTVLKGKW

CHD9

2266

Q3L8U1
ALQDTKISEWKLGLC

IFI44

81

Q8TCB0
AVIKCGKWVQLQLAE

CCDC141

31

Q6ZP82
WSKKDNRGNLLQCIC

FN1

246

P02751
LKLSLQAQSQILGWC

CALHM5

171

Q8N5C1
ELFCVGIQLLNKTWK

ELMO3

441

Q96BJ8
LCIWLGSQIKSLCNL

FAM98B

51

Q52LJ0
PDGFKILLRQCWNSK

MAP3K12

336

Q12852
LRCLWLQSNGIQKIE

DNAAF1

131

Q8NEP3
AKVGQLFAAWKLQLL

HAPLN4

301

Q86UW8
WDTQTLKCLSLLKGQ

EML6

756

Q6ZMW3
LKCLNSLRGWKILNQ

DIRC1

86

Q969H9
NKLAETLRWCLNLGI

DHDDS

56

Q86SQ9
NAKSWVISLGKLLNE

DNAH10

1061

Q8IVF4
WGNLKLFLRQCKLVE

RYK

416

P34925
QKLGVSKLNCWLIQG

DPY19L2P2

226

Q6ZN68
RDWCQQLGLSTNGKK

DPPA2

101

Q7Z7J5
QRVWKILQKCHGLSI

PHKA2

1086

P46019
ISCLIQKAQWTVGKL

RNF180

71

Q86T96
NKTKTALGFLLWIVC

ABCC1

71

P33527
QEPQSGFWTLRLCKK

TRIM38

376

O00635
RAKWGLLKNIQSALQ

TRIM42

706

Q8IWZ5
RLLNIACAAKAKWRQ

RAPGEF6

516

Q8TEU7
SRQCGMKLQSLLQKW

SYNE2

4826

Q8WXH0
WQRCLGSALNVIKKA

SYNRG

1131

Q9UMZ2
KILLQINCKLGGELW

PIWIL2

716

Q8TC59
KCLLFWCRKIVGNRQ

TMEM183BP

236

Q1AE95
QDTAGCSQWLKALLK

TAF1C

631

Q15572
FLNLKNKWIGEIRSN

RHOH

91

Q15669
GKQLLKDKSIRCSNW

WRN

186

Q14191
LQLFMGNLRNKCLQW

SCN3A

266

Q9NY46
LSDCQALGKQARWKN

SCN3A

1381

Q9NY46
SQLQLLIKKWRSCSQ

SFR1

186

Q86XK3
VCFLGFIIQLNWKKA

SLC47A1

451

Q96FL8
TQIWKGLCIESKQLV

SPAG17

1736

Q6Q759
QLFKTQNKGWGIRCL

SETDB1

806

Q15047
GCLWDLKVQEALLNK

ADGRF5

1266

Q8IZF2
LQKHGNEVCKQIWLG

AGFG1

81

P52594
KLIQNWKIGLMCFLS

CLEC2A

21

Q6UVW9
RQCWQLGSNLLKIDS

CLEC7A

146

Q9BXN2
VKCKLNGFQWSLEVI

NCAPD3

781

P42695
WLCLTLGLQRSKNNK

PIGV

351

Q9NUD9
NQEIWGIKCRLTLQK

SKP2

406

Q13309
ICKNLKVKTQAWRVG

AVPR1B

226

P47901
KDCWRTFLNQSSLKL

ZNF846

201

Q147U1
RDWLVCLAKQKNGIL

TRMT61B

391

Q9BVS5
KCLLFWCRKIVGNRQ

TMEM183A

236

Q8IXX5
ILALQLCGWIKKGTD

MIOS

491

Q9NXC5
ENKIKWINFLALGCS

ROPN1L

121

Q96C74
DGLLQLWKKKCCILT

PHLDA1

161

Q8WV24
CQLVAQKVKSLLWGQ

TCTN1

451

Q2MV58
RINLLVKSFIKWCNS

THOC7

26

Q6I9Y2
NIKWRSTCGKQNLLQ

PKHD1L1

986

Q86WI1
AASKFAQLQCLWKTR

SLC66A3

126

Q8N755
SWKKLQCLKNLETLD

TLR7

691

Q9NYK1
GLLCQFNEKRVLEKW

WDR62

276

O43379
ACSKDLTLLWIQQIK

UBE3B

121

Q7Z3V4
WNLKKGVFNKSRCTI

ZMYM5

326

Q9UJ78
IVGNLACLRKNQLWG

ZGRF1

2036

Q86YA3
HETLKQLRKLCFQWL

ZNF18

56

P17022
NLDNVCKKGNTLLWD

USP34

851

Q70CQ2
LSTWDQRKKQLLGCL

TRANK1

436

O15050
VLCSQQWKLLSQKEK

UBTF

326

P17480
GNICLDILKEKWSAL

UBE2C

111

O00762
KSLIQWEKDGRCLQN

ADAMTSL3

941

P82987
LCSLAADGLWNQKIL

NLRP12

461

P59046
RLQKLWLDSCGLTAK

NLRP12

971

P59046
LTKKQGLLASENWTL

MYO7B

1531

Q6PIF6