Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA4 PLXNA1 PLXNA2	6.77e-06	12	64	3	GO:0017154
GeneOntologyMolecularFunction	cytokine binding	CD109 CD44 IL18R1 IL23R IFNAR1	1.48e-04	157	64	5	GO:0019955
GeneOntologyMolecularFunction	cytokine receptor activity	CD44 IL18R1 IL23R IFNAR1	2.66e-04	97	64	4	GO:0004896
GeneOntologyBiologicalProcess	regulation of cell shape	FN1 PLXNA4 HCK PLXNA1 PLXNA2 STRIP2	8.22e-06	159	62	6	GO:0008360
GeneOntologyBiologicalProcess	regulation of cell morphogenesis	FN1 CD44 PLXNA4 HCK PLXNA1 PLXNA2 STRIP2	3.32e-05	302	62	7	GO:0022604
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA4 PLXNA1 PLXNA2	7.30e-06	13	63	3	GO:0002116
Domain	Plexin_cytopl	PLXNA4 PLXNA1 PLXNA2	2.88e-06	9	62	3	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA4 PLXNA1 PLXNA2	2.88e-06	9	62	3	IPR013548
Domain	Plexin	PLXNA4 PLXNA1 PLXNA2	2.88e-06	9	62	3	IPR031148
Domain	IPT	PLXNA4 PLXNA1 PLXNA2	9.63e-05	27	62	3	SM00429
Domain	TIG	PLXNA4 PLXNA1 PLXNA2	1.47e-04	31	62	3	PF01833
Domain	Sema	PLXNA4 PLXNA1 PLXNA2	1.47e-04	31	62	3	SM00630
Domain	Semap_dom	PLXNA4 PLXNA1 PLXNA2	1.47e-04	31	62	3	IPR001627
Domain	Sema	PLXNA4 PLXNA1 PLXNA2	1.47e-04	31	62	3	PF01403
Domain	SEMA	PLXNA4 PLXNA1 PLXNA2	1.47e-04	31	62	3	PS51004
Domain	PSI	PLXNA4 PLXNA1 PLXNA2	1.61e-04	32	62	3	PF01437
Domain	IPT	PLXNA4 PLXNA1 PLXNA2	1.61e-04	32	62	3	IPR002909
Domain	Plexin_repeat	PLXNA4 PLXNA1 PLXNA2	1.61e-04	32	62	3	IPR002165
Domain	Rho_GTPase_activation_prot	ARHGAP12 PLXNA4 PLXNA1 PLXNA2	2.08e-04	88	62	4	IPR008936
Domain	Ig_E-set	CD109 PLXNA4 PLXNA1 PLXNA2	3.95e-04	104	62	4	IPR014756
Domain	PSI	PLXNA4 PLXNA1 PLXNA2	4.19e-04	44	62	3	IPR016201
Domain	PSI	PLXNA4 PLXNA1 PLXNA2	4.78e-04	46	62	3	SM00423
Domain	A2M_N	CD109 PZP	4.80e-04	10	62	2	PF01835
Domain	A2M_N	CD109 PZP	4.80e-04	10	62	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	CD109 PZP	4.80e-04	10	62	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	CD109 PZP	4.80e-04	10	62	2	PS00477
Domain	A2M	CD109 PZP	4.80e-04	10	62	2	PF00207
Domain	A2M_N_2	CD109 PZP	4.80e-04	10	62	2	IPR011625
Domain	A2M_comp	CD109 PZP	4.80e-04	10	62	2	IPR011626
Domain	A2M_N_2	CD109 PZP	4.80e-04	10	62	2	PF07703
Domain	A2M_recep	CD109 PZP	4.80e-04	10	62	2	PF07677
Domain	A2M_comp	CD109 PZP	4.80e-04	10	62	2	PF07678
Domain	Macroglobln_a2	CD109 PZP	4.80e-04	10	62	2	IPR001599
Domain	Terpenoid_cyclase/PrenylTrfase	CD109 PZP	1.60e-03	18	62	2	IPR008930
Domain	Kringle-like	FN1 HABP2	5.04e-03	32	62	2	IPR013806
Domain	-	FN1 PLXNA4 IL18R1 PLXNA1 PLXNA2 IL23R IFNAR1	6.23e-03	663	62	7	2.60.40.10
Domain	Ig-like_fold	FN1 PLXNA4 IL18R1 PLXNA1 PLXNA2 IL23R IFNAR1	8.67e-03	706	62	7	IPR013783
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 PLXNA1 PLXNA2	2.69e-06	9	46	3	MM15030
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 PLXNA1 PLXNA2	1.15e-05	14	46	3	MM15029
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 PLXNA1 PLXNA2	1.15e-05	14	46	3	M7578
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 PLXNA1 PLXNA2	1.44e-05	15	46	3	MM15031
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 PLXNA1 PLXNA2	1.77e-05	16	46	3	M16498
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 PLXNA1 PLXNA2	1.77e-05	16	46	3	M8245
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	PLXNA4 PLXNA1 PLXNA2	3.04e-05	19	46	3	M10959
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	PLXNA4 PLXNA1 PLXNA2	6.07e-04	51	46	3	MM14967
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA1 PLXNA2	5.94e-09	3	64	3	27397516
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA1 PLXNA2	5.94e-09	3	64	3	18625214
Pubmed	Co-localization of insulin-like growth factor binding protein 3 and fibronectin in human articular cartilage.	IGFBP3 FN1 CD44	5.94e-09	3	64	3	12127836
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	GCM2 PLXNA4 PLXNA1 PLXNA2	1.87e-08	16	64	4	18489001
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA4 PLXNA1 PLXNA2	2.37e-08	4	64	3	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA4 PLXNA1 PLXNA2	2.37e-08	4	64	3	25518740
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA4 PLXNA1 PLXNA2	2.07e-07	7	64	3	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA4 PLXNA1 PLXNA2	2.07e-07	7	64	3	19655386
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA4 PLXNA1 PLXNA2	3.31e-07	8	64	3	15661641
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA4 PLXNA1 PLXNA2	3.31e-07	8	64	3	22368082
Pubmed	The role of neuropilins in cell signalling.	PLXNA4 PLXNA1 PLXNA2	4.95e-07	9	64	3	19909241
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA4 PLXNA1 PLXNA2	7.07e-07	10	64	3	18804103
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXNA4 PLXNA1 PLXNA2	1.29e-06	12	64	3	25839327
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA4 PLXNA1 PLXNA2	1.29e-06	12	64	3	31690636
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA4 PLXNA1 PLXNA2	1.29e-06	12	64	3	24179230
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA4 PLXNA1 PLXNA2	1.29e-06	12	64	3	23991118
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA4 PLXNA1 PLXNA2	1.29e-06	12	64	3	28407732
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA4 PLXNA1 PLXNA2	1.29e-06	12	64	3	21270798
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA4 PLXNA1 PLXNA2	1.68e-06	13	64	3	25959730
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA4 PLXNA1 PLXNA2	1.68e-06	13	64	3	10520995
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA4 PLXNA1 PLXNA2	1.68e-06	13	64	3	11604131
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA4 PLXNA1 PLXNA2	1.68e-06	13	64	3	22723296
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	PLXNA4 PLXNA1 PLXNA2	2.13e-06	14	64	3	20159958
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	SBF1 MAX KCTD10 NUP133 TASOR STRIP2	2.67e-06	212	64	6	33853758
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SERBP1 FN1 SBF1 NUP133 LARP1 ZFR EWSR1 RAI1 PPP6R3	3.01e-06	653	64	9	22586326
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA4 PLXNA1 PLXNA2	3.27e-06	16	64	3	17356169
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	PLXNA4 PLXNA1 PLXNA2	3.27e-06	16	64	3	22632726
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	3.33e-06	2	64	2	10781943
Pubmed	Phosphorylation of IGFBP-3 by Casein Kinase 2 Blocks Its Interaction with Hyaluronan, Enabling HA-CD44 Signaling Leading to Increased NSCLC Cell Survival and Cisplatin Resistance.	IGFBP3 CD44	3.33e-06	2	64	2	36766747
Pubmed	HIPK2 is necessary for type I interferon-mediated antiviral immunity.	HIPK2 IFNAR1	3.33e-06	2	64	2	30890658
Pubmed	EWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma.	EWSR1 BEND2	3.33e-06	2	64	2	34825267
Pubmed	Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.	NFIL3 IFNAR1	3.33e-06	2	64	2	24909887
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNA4 PLXNA1 PLXNA2	3.97e-06	17	64	3	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA4 PLXNA1 PLXNA2	3.97e-06	17	64	3	17626059
Pubmed	Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis.	KCTD13 HLTF VCPIP1	8.93e-06	22	64	3	22902628
Pubmed	Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	9.99e-06	3	64	2	17296555
Pubmed	Spinal cord astroblastoma with an EWSR1-BEND2 fusion classified as a high-grade neuroepithelial tumour with MN1 alteration.	EWSR1 BEND2	9.99e-06	3	64	2	31863478
Pubmed	Identification of plexin family molecules in mice.	PLXNA1 PLXNA2	9.99e-06	3	64	2	8806646
Pubmed	IGFBP-3 and IGFBP-5 associate with the cell binding domain (CBD) of fibronectin.	IGFBP3 FN1	9.99e-06	3	64	2	19236847
Pubmed	IGFBP-3 can either inhibit or enhance EGF-mediated growth of breast epithelial cells dependent upon the presence of fibronectin.	IGFBP3 FN1	9.99e-06	3	64	2	20851879
Pubmed	EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.	IGFBP3 EWSR1	9.99e-06	3	64	2	15282325
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	9.99e-06	3	64	2	29091353
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	9.99e-06	3	64	2	36169302
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA1 PLXNA2	9.99e-06	3	64	2	11241833
Pubmed	Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.	PLXNA4 PLXNA2	9.99e-06	3	64	2	22777942
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	PLXNA4 PLXNA1 PLXNA2	1.17e-05	24	64	3	15869472
Pubmed	A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.	PLXNA4 PLXNA1 PLXNA2	1.17e-05	24	64	3	28893946
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	PLXNA4 PLXNA1 PLXNA2	1.88e-05	28	64	3	18617019
Pubmed	ADAMTS18 regulates early branching morphogenesis of lacrimal gland and has a significant association with the risk of dry eye in mice.	FN1 PARD3	2.00e-05	4	64	2	35240198
Pubmed	Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin.	FN1 CD44	2.00e-05	4	64	2	1730778
Pubmed	IL-18 is required for the TH1-adaptation of TREG cells and the selective suppression of TH17 responses in acute and chronic infections.	IL18R1 IFNAR1	2.00e-05	4	64	2	37182738
Pubmed	Hyaluronan inhibits p38 mitogen-activated protein kinase via the receptors in rheumatoid arthritis chondrocytes stimulated with fibronectin fragment.	FN1 CD44	2.00e-05	4	64	2	20552237
Pubmed	Determination of cell adhesion sites of neuropilin-1.	PLXNA1 PLXNA2	2.00e-05	4	64	2	10725340
Pubmed	Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) binds to fibronectin (FN): demonstration of IGF-I/IGFBP-3/fn ternary complexes in human plasma.	IGFBP3 FN1	2.00e-05	4	64	2	11344214
Pubmed	The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module.	CD44 PARD3	2.00e-05	4	64	2	19893486
Pubmed	A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.	PLXNA1 PLXNA2	2.00e-05	4	64	2	8570614
Pubmed	Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.	PLXNA4 PLXNA2	3.32e-05	5	64	2	22593055
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	PLXNA1 PLXNA2	3.32e-05	5	64	2	25313870
Pubmed	The CRL3BTBD9 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration.	KCTD13 KCTD10	3.32e-05	5	64	2	32327643
Pubmed	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	NFIL3 IL18R1 HCK BANK1 IL23R IFNAR1	4.01e-05	342	64	6	23128233
Pubmed	Semaphorin-Plexin signaling influences early ventral telencephalic development and thalamocortical axon guidance.	PLXNA4 PLXNA2	4.98e-05	6	64	2	28438183
Pubmed	Local Inflammatory Cues Regulate Differentiation and Persistence of CD8+ Tissue-Resident Memory T Cells.	IL18R1 IFNAR1	4.98e-05	6	64	2	28380351
Pubmed	Roles of semaphorin-6B and plexin-A2 in lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	4.98e-05	6	64	2	20484647
Pubmed	Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples.	PCLO PARD3	4.98e-05	6	64	2	21621269
Pubmed	IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock.	IL18R1 IFNAR1	4.98e-05	6	64	2	34798063
Pubmed	Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.	KCTD13 KCTD10	4.98e-05	6	64	2	28963344
Pubmed	Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.	PLXNA1 PLXNA2	4.98e-05	6	64	2	19480842
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SLC38A2 SBF1 NRXN2 LARP1 CACNA1G RAI1 PPP6R3	5.32e-05	529	64	7	14621295
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SERBP1 KCTD13 FN1 SBF1 NRXN2 PCLO KCTD10 PLXNA4 LARP1 EWSR1 HCK	5.51e-05	1431	64	11	37142655
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SERBP1 RANBP3 LARP1 ZFR PARD3 PPP6R3 VCPIP1	6.71e-05	549	64	7	38280479
Pubmed	MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+ Dendritic Cells Independently of TNF-α and the Gut Microbiota.	IL18R1 IFNAR1	6.96e-05	7	64	2	26259586
Pubmed	Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.	PLXNA1 PLXNA2	6.96e-05	7	64	2	10520994
Pubmed	Cytomegalovirus Infection Drives Avidity Selection of Natural Killer Cells.	IL18R1 IFNAR1	6.96e-05	7	64	2	31103381
Pubmed	Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection.	IL18R1 IFNAR1	6.96e-05	7	64	2	28264883
Pubmed	The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection.	IL18R1 IFNAR1	6.96e-05	7	64	2	24747678
Pubmed	A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.	ARHGAP12 KHDRBS2 CACNA1G	7.46e-05	44	64	3	32492419
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SLC38A2 YIPF5 SERBP1 RANBP3 CD44 LARP1 VCPIP1	8.29e-05	568	64	7	37774976
Pubmed	The N-terminal domain of the Schaaf-Yang syndrome protein MAGEL2 likely has a role in RNA metabolism.	SERBP1 RANBP3 LARP1	8.53e-05	46	64	3	34265304
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	PLXNA4 PLXNA1 PLXNA2	9.09e-05	47	64	3	35462405
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	IGFBP3 FN1 CD109 CD44 PZP	1.13e-04	257	64	5	16335952
Pubmed	PlexinA2 and semaphorin signaling during cardiac neural crest development.	PLXNA1 PLXNA2	1.19e-04	9	64	2	11688557
Pubmed	Semaphorin 6A in Retinal Ganglion Cells Regulates Functional Specialization of the Inner Retina.	PLXNA4 PLXNA2	1.19e-04	9	64	2	38014224
Pubmed	Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.	PLXNA4 PLXNA1	1.19e-04	9	64	2	28751609
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	YIPF5 NFIL3 MAX NUP133 HLTF ZFR EWSR1 TASOR RAI1 VCPIP1	1.19e-04	1294	64	10	30804502
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXNA4 PLXNA1 PLXNA2	1.23e-04	52	64	3	26633812
Pubmed	TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules.	SERBP1 EWSR1	1.49e-04	10	64	2	18632687
Pubmed	Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis.	SYCP2 TEX15	1.49e-04	10	64	2	18283110
Pubmed	Identification of two clusters of mouse insulin-like growth factor binding protein genes on chromosomes 1 and 11.	IGFBP3 FN1	1.49e-04	10	64	2	7525452
Pubmed	CD44 regulates tight-junction assembly and barrier function.	CD44 PARD3	1.49e-04	10	64	2	21191420
Pubmed	KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13.	KCTD13 KCTD10	1.49e-04	10	64	2	38489388
Pubmed	Class 3 semaphorins negatively regulate dermal lymphatic network formation.	PLXNA1 PLXNA2	1.81e-04	11	64	2	26319580
Pubmed	Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.	IL18R1 IL23R	1.81e-04	11	64	2	23034650
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SBF1 HLTF LARP1 EWSR1 PZP TASOR PCDHGC3	1.90e-04	650	64	7	38777146
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	FN1 PCLO RDH14 LARP1 EWSR1 WNK3	2.08e-04	462	64	6	31138677
Pubmed	IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization.	IL18R1 IL23R	2.17e-04	12	64	2	27551155
Pubmed	The loop-tail mouse model displays open and closed caudal neural tube defects.	CD44 HABP2	2.17e-04	12	64	2	37589570
Pubmed	A cell polarity protein aPKClambda is required for eye lens formation and growth.	FN1 PARD3	2.17e-04	12	64	2	19835853
Pubmed	The human plasma proteome: a nonredundant list developed by combination of four separate sources.	IGFBP3 FN1 HABP2 PZP	2.49e-04	165	64	4	14718574
Pubmed	Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.	NLRP9 IFNAR1	2.57e-04	13	64	2	28636595
Pubmed	Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes.	IGFBP3 FN1 NFIL3	2.86e-04	69	64	3	15142957
Interaction	SEMA5A interactions	PLXNA4 PLXNA1 PLXNA2	9.16e-07	7	61	3	int:SEMA5A
Interaction	PCLO interactions	SERBP1 KCTD13 PCLO KCTD10 EWSR1	2.24e-06	70	61	5	int:PCLO
Interaction	SEMA5B interactions	PLXNA4 PLXNA1 PLXNA2	1.17e-05	15	61	3	int:SEMA5B
Interaction	IGFBP3 interactions	IGFBP3 FN1 SBF1 CD44	3.48e-05	61	61	4	int:IGFBP3
Interaction	SF1 interactions	FN1 RANBP3 KCTD10 ARHGAP12 KHDRBS2 ZFR EWSR1	3.60e-05	304	61	7	int:SF1
Interaction	SEMA6D interactions	PLXNA4 PLXNA1 PLXNA2	4.48e-05	23	61	3	int:SEMA6D
Interaction	PPIAP22 interactions	FN1 EWSR1	5.39e-05	4	61	2	int:PPIAP22
Interaction	LGALS1 interactions	FN1 CD109 CD44 HCK PLXNA1 PLXNA2 IFNAR1	6.29e-05	332	61	7	int:LGALS1
GeneFamily	Plexins	PLXNA4 PLXNA1 PLXNA2	7.73e-07	9	39	3	683
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CD109 PZP	1.62e-04	9	39	2	1234
Coexpression	FAN_EMBRYONIC_CTX_BIG_GROUPS_EXCITATORY_NEURON	DOCK9 PCLO PLXNA4 PLXNA2	5.33e-06	47	64	4	M39019
Coexpression	VERRECCHIA_EARLY_RESPONSE_TO_TGFB1	IGFBP3 FN1 CD44 PCDHGC3	9.33e-06	54	64	4	M4737
Coexpression	GSE30083_SP3_VS_SP4_THYMOCYTE_DN	KCTD10 SIDT1 CD44 MPEG1 IL18R1 BANK1	9.50e-06	200	64	6	M5037
Coexpression	WILCOX_RESPONSE_TO_PROGESTERONE_DN	IGFBP3 FN1 HIPK2 PCDHGC3	1.62e-05	62	64	4	M16774
Coexpression	GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN	TMEM87B ARHGAP12 SIDT1 IL18R1 IL23R	2.83e-05	145	64	5	M359
Coexpression	PETRETTO_CARDIAC_HYPERTROPHY	IGFBP3 FN1 CD44	7.87e-05	34	64	3	M14043
Coexpression	BUSSLINGER_GASTRIC_G_CELLS	PCLO SHISAL2B RFX6 PLXNA2	9.83e-05	98	64	4	M40018
Coexpression	RIZ_ERYTHROID_DIFFERENTIATION_6HR	GCM2 NFIL3 HLTF	1.10e-04	38	64	3	M1854
Coexpression	RIZ_ERYTHROID_DIFFERENTIATION_6HR	GCM2 NFIL3 HLTF	1.10e-04	38	64	3	MM512
Coexpression	CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP	AMD1 SLC38A2 NFIL3 DOCK9	1.15e-04	102	64	4	M12300
Coexpression	GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN	KCTD10 HLTF LARP1 MPEG1 PLXNA1	1.30e-04	200	64	5	M5120
Coexpression	GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP	MAX SIDT1 LARP1 MPEG1 HCK	1.30e-04	200	64	5	M8564
Coexpression	GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP	SLC38A2 GCM2 NFIL3 MPEG1 HCK	1.30e-04	200	64	5	M8534
Coexpression	GSE17721_LPS_VS_CPG_2H_BMDC_UP	YIPF5 NFIL3 CD44 HLTF LARP1	1.30e-04	200	64	5	M3989
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 FN1 DOCK9 CD109 SIDT1 PLXNA2	3.11e-07	189	64	6	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	(02)_Cycling_Basal_(regeneration)-(1)_24hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	AMD1 SLC38A2 SERBP1 IGFBP3 CD109 CD44	3.11e-07	189	64	6	311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 IGFBP3 FN1 DOCK9 CD109 PLXNA2	3.41e-07	192	64	6	bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FN1 NFIL3 CD44 MPEG1 IL18R1	3.44e-06	160	64	5	6ed37d1fd0304932319d6b942502404115ff36a7
ToppCell	CD8+_Memory_T_cell-FLU-1\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	NFIL3 SIDT1 PZP PLXNA1 IL23R	3.65e-06	162	64	5	76f39935763848ea6e7917b2f9f1432c543063d9
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 CD44 MPEG1 HCK	4.49e-06	169	64	5	907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCell	droplet-Lung-18m-Hematologic-myeloid\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 CD44 MPEG1 HCK	4.76e-06	171	64	5	33869b9fab2c94cb33f1cc659073fcf2bb30c22d
ToppCell	droplet-Lung-21m-Hematologic-myeloid\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 CD44 MPEG1 HCK	4.76e-06	171	64	5	22ad6de44e1d3f72a3d78d46fd26a5743a4f84a5
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 CD44 MPEG1 HCK	4.89e-06	172	64	5	f557ec1b4d08b42559da02dd1f2387283c6380a2
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A2 MPEG1 TASOR VCPIP1 IFNAR1	5.03e-06	173	64	5	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A2 MPEG1 TASOR VCPIP1 IFNAR1	5.03e-06	173	64	5	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A2 MPEG1 TASOR VCPIP1 IFNAR1	5.03e-06	173	64	5	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A2 MPEG1 TASOR VCPIP1 IFNAR1	5.32e-06	175	64	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 PARD3 IL18R1 IL23R	5.78e-06	178	64	5	408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IGFBP3 DOCK9 PKDCC PZP IL18R1	5.94e-06	179	64	5	b0585a8e596c3d8e434af943e65207fa5877600d
ToppCell	COVID-19-kidney-Bcells\|kidney / Disease (COVID-19 only), tissue and cell type	KHDRBS2 SIDT1 CD44 MPEG1 BANK1	6.11e-06	180	64	5	5650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 KHDRBS2 SIDT1 CD44 SHISAL2B	6.11e-06	180	64	5	0677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	AMD1 TMEM87B DOCK9 SIDT1 PLXNA2	7.35e-06	187	64	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	IGFBP3 FN1 DOCK9 CD109 PLXNA2	7.94e-06	190	64	5	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 DOCK9 CD109 SIDT1 PLXNA2	8.35e-06	192	64	5	56b021c297a21dff357531f21e2464f85186106d
ToppCell	367C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KHDRBS2 CD109 CD44 IL18R1 DISP1	8.56e-06	193	64	5	5c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCell	367C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KHDRBS2 CD109 CD44 IL18R1 DISP1	8.56e-06	193	64	5	d4b58eee97043b4337ec36c40f9af6499d864df9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 DOCK9 CD109 SIDT1 PLXNA2	9.00e-06	195	64	5	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO2 IGFBP3 CD109 CACNA1G TEX15	9.00e-06	195	64	5	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMO2 IGFBP3 CD109 CACNA1G TEX15	9.00e-06	195	64	5	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 FN1 DOCK9 CD109 PLXNA2	9.23e-06	196	64	5	a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	AMD1 IGFBP3 FN1 DOCK9 CD109	1.02e-05	200	64	5	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	AMD1 IGFBP3 FN1 DOCK9 CD109	1.02e-05	200	64	5	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	ASK440-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	FMO2 IGFBP3 FN1 HCK	5.22e-05	142	64	4	ea694a907eaa46c55665692cb830870281700e40
ToppCell	droplet-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 MPEG1 HABP2 HCK	5.36e-05	143	64	4	4d11d53330a9197275a8851e1bbf55a113715a09
ToppCell	droplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 MPEG1 HABP2 HCK	5.36e-05	143	64	4	8b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT\|GI_small-bowel / Manually curated celltypes from each tissue	NRXN2 PZP IL23R STRIP2	5.81e-05	146	64	4	1cb2e157222631e8915d89b255a843d16d7d99cc
ToppCell	facs-Lung-Endomucin-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 MPEG1 HCK	6.80e-05	152	64	4	962f5bf632da79bd933193d3edd7d89941a85831
ToppCell	Children_(3_yrs)-Immune-mast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHISAL2B IL18R1 WNK3 IL23R	6.97e-05	153	64	4	d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	7.15e-05	154	64	4	27f76e4b3c055aa382708f1610c685f02d6d6114
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMO2 FN1 DOCK9 CD109	7.15e-05	154	64	4	e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCell	facs-Lung-Endomucin-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	7.15e-05	154	64	4	8746663a822d93a8510081c81a8c971b51653067
ToppCell	10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3\|bone_marrow / Manually curated celltypes from each tissue	PKDCC MYO18B IL18R1 IL23R	7.33e-05	155	64	4	83430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCell	facs-MAT-Fat-24m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 MPEG1 HCK STRIP2	7.33e-05	155	64	4	d0c1608f8f6b6f4174e51d610501c707cba5e015
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-fibrocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 IL18R1 HCK IL23R	7.51e-05	156	64	4	5b56217336771baf57d791efcb4e206c6aea83b1
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	7.89e-05	158	64	4	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	7.89e-05	158	64	4	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	FLU-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	SIDT1 PZP PLXNA1 IL23R	8.09e-05	159	64	4	97c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCell	FLU-Healthy-1\|FLU / Virus stimulation, Condition and Cluster	SIDT1 PZP PLXNA1 IL23R	8.09e-05	159	64	4	fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	YIPF5 IGFBP3 SYNM DNAH9	8.29e-05	160	64	4	529034a1101d7772d82f86beb5c6fa9c9dd97067
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 IL18R1 BANK1 IL23R	8.29e-05	160	64	4	94e4f5fc2156dd8163811c3b8b0781ea9b3f2e06
ToppCell	LAM-Lymphoid-pDC\|LAM / Condition, Lineage and Cell class	SIDT1 PLXNA4 MPEG1 PCDHGC3	8.49e-05	161	64	4	bb5b44713e4da4406cdaa79dcf2aa9f97e3cf75a
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	PLXNA4 PKDCC IL18R1 IL23R	8.91e-05	163	64	4	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	facs-MAT-Fat-3m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 MPEG1 HCK STRIP2	9.12e-05	164	64	4	1250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	9.12e-05	164	64	4	cd0794f84dfd346807e2d803723718b7f22e9232
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	9.12e-05	164	64	4	12251a49fd4af32d4edb58046245548c260cf04b
ToppCell	facs-MAT-Fat-3m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 MPEG1 HCK STRIP2	9.12e-05	164	64	4	fa0d77b648cde5e42b9394e877168c80de238bde
ToppCell	droplet-Kidney-nan-24m-Myeloid-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 CD44 MPEG1 HCK	9.12e-05	164	64	4	d57faa4fce1f1e9a92aaf5cb920af99323252e4b
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYCP2 SHISAL2B CACNA1G TEX15	9.12e-05	164	64	4	f9a2cc12179d5621c9174ec01d7418a71edd28d1
ToppCell	droplet-Kidney-nan-24m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 CD44 MPEG1 HCK	9.12e-05	164	64	4	d0b6c29e61d15f4dbe4c1f6e5ed3e10f41f820ab
ToppCell	droplet-Kidney-nan-24m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 CD44 MPEG1 HCK	9.12e-05	164	64	4	718cc64b7ef7d03d095be4b2b54c449154da568c
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 CD44 MPEG1 HCK	9.34e-05	165	64	4	1d844d19ff9b49dd0f61f0b24799e172076771ef
ToppCell	facs-BAT-Fat-3m-Myeloid-myeloid_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 MPEG1 HCK	9.34e-05	165	64	4	bfe330751d34813af7540765b490406078c40da7
ToppCell	facs-Lung-nan-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 MPEG1 HCK	9.34e-05	165	64	4	720649f330382ea2a68c64a5344160a048afb8f1
ToppCell	NS-control-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SIDT1 PLXNA4 MPEG1 IL18R1	9.34e-05	165	64	4	8b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 CD44 MPEG1 HCK	9.34e-05	165	64	4	9a6abd0e6b11860231ce5e845c87b8d66f3ef697
ToppCell	facs-BAT-Fat-3m-Myeloid\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 MPEG1 HCK	9.34e-05	165	64	4	8bdeacbb47948fabae2575689f811a9fad47f779
ToppCell	control-Myeloid-pDC\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SIDT1 PLXNA4 MPEG1 IL18R1	9.34e-05	165	64	4	243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 CD44 MPEG1 HCK	9.34e-05	165	64	4	433771abefc5bcb89bdae64af45cce7407bffe5d
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MPEG1 EWSR1 HCK BANK1	9.56e-05	166	64	4	063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	9.56e-05	166	64	4	bf6c35c3e67ef4ca98a38926c6f7923ecca0508a
ToppCell	PND28-Immune-Immune_Myeloid\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 CD44 MPEG1 HCK	9.56e-05	166	64	4	caa992944bc7488a6868dbd1902bc3ead6945eb1
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MPEG1 EWSR1 HCK BANK1	9.56e-05	166	64	4	417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCell	facs-Lung-EPCAM-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	9.56e-05	166	64	4	433128b7d964b32faa0bf437a02facc819ab1405
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MPEG1 EWSR1 HCK BANK1	9.56e-05	166	64	4	f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	9.56e-05	166	64	4	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	droplet-Lung-nan-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 MPEG1 HCK	1.00e-04	168	64	4	da1eee804456d910c17f145a5ce79c74a808a2c2
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.00e-04	168	64	4	ba9ddd403ee6d6af2fe56dffbd419764bfb703e4
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.00e-04	168	64	4	af4c35c0d3f030cef8397c35fa498a71112bb16b
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.00e-04	168	64	4	0ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.00e-04	168	64	4	ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell	facs-Lung-EPCAM-24m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.02e-04	169	64	4	c934cf5b6decf6eee78243ee15c2a2c71e14cf71
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.02e-04	169	64	4	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.02e-04	169	64	4	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.02e-04	169	64	4	7503373fd9020c923e7eb96c7695f34054438e9e
ToppCell	facs-BAT-Fat-18m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 MPEG1 HCK	1.10e-04	172	64	4	36fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 CD44 MPEG1 HCK	1.10e-04	172	64	4	e72966ced5f2ee9e24ce9fd820d99a69a482a607
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.10e-04	172	64	4	b26fc612f232e8e273825ac2d2e5519cbb7322cf
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.10e-04	172	64	4	a53c906539557594ef10368bc29aec4af063fd37
ToppCell	facs-BAT-Fat-3m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.10e-04	172	64	4	5f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell	droplet-Lung-LUNG-1m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.10e-04	172	64	4	07bf95ffe77347b4f3159cb88adeaddc1b4796b7
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 CD44 MPEG1 HCK	1.10e-04	172	64	4	83730ea3b240b8e2f2a9fb6c34dd1408050867ff
ToppCell	droplet-Lung-nan-21m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.12e-04	173	64	4	9019049b1e2a24cb0bbbc620d64ef29dd18cc4c6
ToppCell	droplet-Lung-nan-21m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 NFIL3 MPEG1 HCK	1.12e-04	173	64	4	077029eecfe636a5baf5f70464e1713b3f6b4274
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHISAL2B RFX6 HABP2 WNK3	1.12e-04	173	64	4	30fa8c14c8a1f546f380132c0c28a61e6a2f9fc4
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.12e-04	173	64	4	9acad7ec70f713fe3db6cef7bbe3b183bf16ae67
ToppCell	Immune_cells-Monocytes\|Immune_cells / Lineage and Cell class	FN1 NFIL3 MPEG1 HCK	1.12e-04	173	64	4	3eced40a65453a023a1673658592e7e2a099119b
ToppCell	droplet-Lung-nan-21m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIL3 CD44 MPEG1 HCK	1.15e-04	174	64	4	763ca53339d9e236da8463f2a9d1bd39d4385d75
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 DOCK9 CD109 PLXNA2	1.15e-04	174	64	4	3d4c05ea5719ca65e85d1f15198453034791087c
ToppCell	droplet-Liver-Npc-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 MPEG1 HCK BANK1	1.17e-04	175	64	4	1973fff0d7e1a94b31f461a39b91cc7984ebd8f1
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT\|lymph-node_spleen / Manually curated celltypes from each tissue	SLC38A2 PKDCC IL18R1 IL23R	1.20e-04	176	64	4	25c197d3b39deffa4801a1d12cdb54320cbae509
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	IGFBP3 PLXNA4 MPEG1 IL18R1	1.20e-04	176	64	4	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	droplet-Lung-1m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.20e-04	176	64	4	8f9d2a763b79cafe26dcbf3dba980d473a0b9873
ToppCell	droplet-Liver-Npc-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD44 MPEG1 HCK BANK1	1.20e-04	176	64	4	1e430dffddd315d9a1cb4bd7fef5077656351c65
ToppCell	droplet-Lung-1m-Hematologic-myeloid-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 NFIL3 MPEG1 HCK	1.20e-04	176	64	4	3b5d12d5c22e32fbe80c3716ff14a7ae5769c165
Drug	Isoxsuprine hydrochloride [579-56-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	YIPF5 KCTD13 SBF1 RANBP3 PCLO MAX PLXNA1	1.48e-06	200	64	7	4789_DN
Drug	2,2,5,7,8-pentamethyl-1-hydroxychroman	SLC38A2 IGFBP3 FN1 NFIL3 SIDT1 RFX6 DISP1	6.79e-06	252	64	7	ctd:C029141
Disease	anterior uveitis	TMEM87B IL18R1 IL23R	4.61e-05	32	64	3	EFO_1000811
Disease	interleukin 18 receptor 1 measurement	IL18R1 IL23R	4.77e-04	15	64	2	EFO_0008178
Disease	neuroimaging measurement	IGFBP3 DOCK9 ARHGAP12 RDH14 PKDCC PARD3 BANK1 PLXNA2 RAI1	4.78e-04	1069	64	9	EFO_0004346
Disease	cortical surface area measurement	SLC38A2 DOCK9 ARHGAP12 SIDT1 RDH14 HIPK2 PKDCC PARD3 BANK1 PLXNA2	6.01e-04	1345	64	10	EFO_0010736
Disease	Corneal astigmatism	DOCK9 KHDRBS2 PARD3	6.35e-04	77	64	3	EFO_1002040
Disease	cortical thickness	IGFBP3 DOCK9 ARHGAP12 SIDT1 RDH14 PKDCC PARD3 BANK1 PLXNA2	6.38e-04	1113	64	9	EFO_0004840
Disease	ST2 protein measurement	IL18R1 BANK1	9.47e-04	21	64	2	EFO_0010599
Disease	transitional cell carcinoma (is_implicated_in)	IGFBP3 CD44	1.04e-03	22	64	2	DOID:2671 (is_implicated_in)
Disease	Ureteral obstruction	FN1 HIPK2	1.24e-03	24	64	2	C0041956
Disease	systemic scleroderma (is_implicated_in)	BANK1 IL23R	1.24e-03	24	64	2	DOID:418 (is_implicated_in)
Disease	facial width measurement	PCLO HABP2 DISP1	1.56e-03	105	64	3	EFO_0007855
Disease	forced expiratory volume	DOCK9 ARHGAP12 RDH14 PLXNA4 PKDCC LARP1 RFX6	1.58e-03	789	64	7	EFO_0004314
Disease	urinary bladder cancer (is_marker_for)	IGFBP3 FN1 CD44	1.64e-03	107	64	3	DOID:11054 (is_marker_for)
Disease	Early Pregnancy Loss	IGFBP3 FN1 HABP2	1.73e-03	109	64	3	C3830362
Disease	Miscarriage	IGFBP3 FN1 HABP2	1.73e-03	109	64	3	C4552766
Disease	Spontaneous abortion	IGFBP3 FN1 HABP2	1.73e-03	109	64	3	C0000786
Disease	Abortion, Tubal	IGFBP3 FN1 HABP2	1.73e-03	109	64	3	C0000822

Protein segments in the cluster

Peptide	Gene	Start	Entry
YYEFQSLQTEICSQN	BANK1	321	Q8NDB2
NRSNNKYSYTSTSDD	KCTD13	176	Q8WZ19
TSYDQSSYSQQNTYG	EWSR1	201	Q01844
SYSQAPSQYSQQSSS	EWSR1	246	Q01844
NRSNNKYSYTSNSDD	KCTD10	166	Q9H3F6
SFTNDSYQVYNVFST	ERVK13-1	6	Q9NX77
SYQVYNVFSTNSFQL	ERVK13-1	11	Q9NX77
NQTFFYQTDEQDFTS	DISP1	836	Q96F81
TNYFLQYISSSLENS	RANBP3	296	Q9H6Z4
NYQQTSQETSRLENY	RAI1	16	Q7Z5J4
FISVNDANYYSNATT	PZP	381	P20742
QANHDFYSTSSNYQT	RFX6	691	Q8HWS3
FYSTSSNYQTVFRAQ	RFX6	696	Q8HWS3
NYQSSTSYSINTELS	MPEG1	106	Q2M385
QISYNYSDLDQSNVT	SERBP1	241	Q8NC51
NFSNQTAYLYNESAV	NUP133	411	Q8WUM0
NNITYYFDNVSSTEL	LARP1	381	Q6PKG0
ENSYYQTLVNSTSLY	IL18R1	141	Q13478
YSDSSSNTSPYSVQQ	HIPK2	926	Q9H2X6
LQTNYPSSDNSLYTN	MAX	111	P61244
TTETNVENNSQTVYY	BEND2	356	Q8NDZ0
KYSSQTSQDSGNYSN	IFNAR1	526	P17181
TSYTQQSHFEQQTLY	PCLO	3901	Q9Y6V0
NSSSLQCQNSSYSYE	PLXNA1	761	Q9UIW2
NSSSVQCQNSSYQYD	PLXNA2	756	O75051
NSSSVQCQNTSYSYE	PLXNA4	756	Q9HCM2
LSNSTAVYFQDYQTS	NFIL3	141	Q16649
SNSLQTYELSRNEYF	PCDHGC3	166	Q9UN70
QSSQSSYDVYIEENN	PCDHGC3	456	Q9UN70
SSESSEYQSYSQYQS	FAM170B	76	A6NMN3
EENYYSTSYSQSDSQ	ARHGAP12	321	Q8IWW6
LYSQFQTAESENRSY	SBF1	1751	O95248
SYQVDQSRNYISNSA	NRXN2	621	P58401
YEDYNQEENTSSTLT	HABP2	46	Q14520
NDQTYYQSFQVSEYV	CD109	211	Q6YHK3
LDDFYTATESQYQQQ	HCK	511	P08631
NVSSDFPNYVNSSYI	DOCK9	591	Q9BZ29
DYEAYNSSSNTTCVN	CACNA1G	301	O43497
ILTSNTSQYDTYCFN	CD44	106	P16070
ISQTEFPTTYYQNAT	GFY	256	I3L273
CSTTSNYEQDQKYSF	FN1	386	P02751
SYVSFETNLSQTSYD	AMD1	251	P17707
QQYLTSSYINISTDS	IL23R	171	Q5VWK5
GESQSQTLQTNYVDY	FMO2	421	Q99518
DDQTYETYDNSYATQ	KHDRBS2	281	Q5VWX1
ETYDNSYATQTQSVP	KHDRBS2	286	Q5VWX1
SQSYLSNEQRYNYTT	DNAH9	3026	Q9NYC9
QRNDLYYNTITNFSE	HLTF	266	Q14527
YEQLSQSEKNNYYSS	PARD3	366	Q8TEW0
YKVDYESQSTDTQNF	IGFBP3	186	P17936
QYLQNSTASSSTEYQ	PKDCC	396	Q504Y2
SELYSYTENLEFTNN	STRIP2	66	Q9ULQ0
SGYSSSATTQQENSY	SYNM	401	O15061
QCNVNSYSSYERSFD	GCM2	311	O75603
LNSNAASNATNETYY	SHISAL2B	126	A6NKW6
NSEQSYNKSFCYSRS	RDH14	206	Q9HBH5
SQENENYFLSAYTES	TASOR	1631	Q9UK61
DLEINSQNTTYLYAS	NLRP9	356	Q7RTR0
SSNSDFNYSYPTKQA	SLC38A2	21	Q96QD8
VNLSTENIYSFNYTS	SIDT1	56	Q9NXL6
TQNSNSYSDVSSYSS	SYCP2	1211	Q9BX26
QYESDSSLNSNVYDV	VCPIP1	611	Q96JH7
NLNTDFYQTSYSIDD	YIPF5	6	Q969M3
FYQTSYSIDDQSQQS	YIPF5	11	Q969M3
ATSESQQRESSQYYQ	MYO18B	2011	Q8IUG5
FYSEYQNISNTGLST	TMEM87B	266	Q96K49
TQNYQDSYSYVRSTA	ZFR	136	Q96KR1
NYFYSSTQNNETELT	TEX15	751	Q9BXT5
STVTELEYNYNQFST	TEX15	2196	Q9BXT5
FSQDSSLQQAFSDYQ	PPP6R3	536	Q5H9R7
EEQAYAQTQSSLFYS	WNK3	1501	Q9BYP7