Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain binding

RPRD2 RPRD1B

1.36e-0411322GO:0099122
GeneOntologyCellularComponentcollagen type XI trimer

COL5A1 COL11A2

2.26e-055322GO:0005592
GeneOntologyCellularComponentfibrillar collagen trimer

COL5A1 COL11A2

1.48e-0412322GO:0005583
GeneOntologyCellularComponentbanded collagen fibril

COL5A1 COL11A2

1.48e-0412322GO:0098643
GeneOntologyCellularComponenttranscription preinitiation complex

RPRD2 RPRD1B

2.35e-0415322GO:0097550
GeneOntologyCellularComponentcomplex of collagen trimers

COL5A1 COL11A2

4.68e-0421322GO:0098644
GeneOntologyCellularComponentcalyx of Held

PRKCA UNC13C

1.38e-0336322GO:0044305
HumanPhenoIncreased VLDL cholesterol concentration

UBR1 LCAT

3.04e-054122HP:0003362
HumanPhenoAbnormal VLDL cholesterol concentration

UBR1 LCAT

3.04e-054122HP:0031889
HumanPhenoBowel diverticulosis

UBR1 COL5A1 GTF2I

7.42e-0537123HP:0005222
DomainCREPT

RPRD2 RPRD1B

8.52e-063322IPR032337
DomainCREPT

RPRD2 RPRD1B

8.52e-063322PF16566
DomainRNA_pol_II-bd

RPRD2 RPRD1B

5.94e-057322IPR006903
DomainCTD_bind

RPRD2 RPRD1B

5.94e-057322PF04818
DomainRPR

RPRD2 RPRD1B

7.91e-058322SM00582
DomainCID

RPRD2 RPRD1B

7.91e-058322PS51391
DomainCID_dom

RPRD2 RPRD1B

7.91e-058322IPR006569
DomainFib_collagen_C

COL5A1 COL11A2

1.55e-0411322IPR000885
DomainCOLFI

COL5A1 COL11A2

1.55e-0411322PF01410
DomainNC1_FIB

COL5A1 COL11A2

1.55e-0411322PS51461
DomainFib_collagen_C

COL5A1 COL11A2

1.55e-0411322PD002078
DomainCOLFI

COL5A1 COL11A2

1.55e-0411322SM00038
DomainSH3

SASH1 MYO15A SKAP2 SH3PXD2A

4.85e-04216324SM00326
DomainSH3

SASH1 MYO15A SKAP2 SH3PXD2A

4.85e-04216324PS50002
DomainSH3_domain

SASH1 MYO15A SKAP2 SH3PXD2A

5.20e-04220324IPR001452
DomainTSPN

COL5A1 COL11A2

7.04e-0423322SM00210
Domain-

RPRD2 RPRD1B

9.01e-04263221.25.40.90
DomainENTH_VHS

RPRD2 RPRD1B

1.12e-0329322IPR008942
DomainLaminin_G_2

COL5A1 COL11A2

2.13e-0340322PF02210
DomainLamG

COL5A1 COL11A2

2.57e-0344322SM00282
DomainC1_1

PRKCA UNC13C

4.28e-0357322PF00130
DomainLaminin_G

COL5A1 COL11A2

4.43e-0358322IPR001791
DomainZF_DAG_PE_1

PRKCA UNC13C

5.37e-0364322PS00479
DomainZF_DAG_PE_2

PRKCA UNC13C

5.37e-0364322PS50081
DomainC1

PRKCA UNC13C

5.53e-0365322SM00109
DomainPE/DAG-bd

PRKCA UNC13C

5.70e-0366322IPR002219
DomainConA-like_dom

COL5A1 COL11A2 RYR3

6.14e-03219323IPR013320
Pubmed

Association Between COL5a1, COL11a1, and COL11a2 Gene Variations and Rotator Cuff Tendinopathy in Young Athletes.

COL5A1 COL11A2

2.46e-06332234009784
Pubmed

Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.

PCSK5 LTBP2

2.46e-06332221700711
Pubmed

The Association of Variants within Types V and XI Collagen Genes with Knee Joint Laxity Measurements.

COL5A1 COL11A2

2.46e-06332236553626
Pubmed

Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse.

COL5A1 COL11A2

4.92e-06432217683922
Pubmed

Association of type XI collagen genes with chronic Achilles tendinopathy in independent populations from South Africa and Australia.

COL5A1 COL11A2

4.92e-06432223624467
Pubmed

Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon.

COL5A1 COL11A2

1.23e-05632221467034
Pubmed

The pro-alpha3(V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains.

COL5A1 COL11A2

1.23e-05632210722718
Pubmed

Control of the RNA polymerase II phosphorylation state in promoter regions by CTD interaction domain-containing proteins RPRD1A and RPRD1B.

RPRD2 RPRD1B

1.23e-05632222231121
Pubmed

Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1).

COL5A1 COL11A2

1.23e-0563228563024
Pubmed

The collagen family members as cell adhesion proteins.

COL5A1 COL11A2

1.23e-05632217876790
Pubmed

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.

MYO15A SKAP2 SH3PXD2A

1.35e-055032319807924
Pubmed

Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.

SASH1 SKAP2 SH3PXD2A

1.90e-055632322745667
Pubmed

The pro-alpha2(XI) collagen gene is expressed in odontoblasts.

COL5A1 COL11A2

2.29e-05832220059976
Pubmed

Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.

PRKCA UNC13C

2.29e-05832227376238
Pubmed

A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23.

COL11A2 GTF2I

2.94e-05932224097066
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

COL5A1 PRKCA COL11A2 ALPG

4.07e-0521032416537572
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NFASC RPRD2 SCAP ZC3H4

5.32e-0522532412168954
Pubmed

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

SMARCA5 GTF2I ZBTB7B

5.34e-057932326446488
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYCN UBR1 SMARCA5 GTF2I ZC3H4 RPRD1B

6.59e-0577432615302935
Pubmed

RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells.

PRKCA MYO15A

8.55e-051532236260679
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PRKCA RPRD2 SMARCA5 GTF2I ZC3H4

9.05e-0550332516964243
Pubmed

Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina.

MYCN PRKCA

1.11e-041732215797020
Pubmed

Maturational disturbance of chondrocytes in Cbfa1-deficient mice.

COL5A1 COL11A2

1.11e-041732210213384
Pubmed

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

SMARCA5 GTF2I

1.24e-041832228068325
Pubmed

N-myc coordinates retinal growth with eye size during mouse development.

MYCN PRKCA

1.24e-041832218198336
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

RPRD2 SMARCA5 GTF2I ZC3H4

1.29e-0428332430585729
Pubmed

Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex.

COL5A1 COL11A2

2.05e-04233228799160
Pubmed

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.

MYCN SMARCA5

2.24e-042432224946904
Pubmed

Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.

COL5A1 COL11A2

2.43e-042532219180518
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

RPRD2 GTF2I RPRD1B

2.56e-0413432325452129
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

RPRD2 SMARCA5 GTF2I RPRD1B

2.60e-0434032424332808
Pubmed

E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs.

SMARCA5 GTF2I

3.05e-042832230277474
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

PRKCA RPRD2 SMARCA5 RPRD1B

3.16e-0435832432460013
Pubmed

Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.

MYCN PRKCA

3.28e-04293227789972
Pubmed

Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response.

SCAP LCAT

3.75e-043132220031551
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

RPRD2 GTF2I ZC3H4 RPRD1B

4.76e-0439932435987950
Pubmed

Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

COL11A2 LCAT

4.79e-043532218193043
Pubmed

Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy.

PRKCA MYBPC2

5.07e-043632223236519
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL5A1 LTBP2 COL11A2

5.58e-0417532328071719
Pubmed

Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

SCAP LCAT

6.58e-044132219878569
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

RPRD2 SMARCA5 GTF2I RPRD1B

6.86e-0444032434244565
Pubmed

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.

PCSK5 SLC44A5

7.23e-044332221116278
Cytoband1q21.3

RPRD2 ZBTB7B

3.04e-031173221q21.3
GeneFamilyActins|Deafness associated genes

COL11A2 MYO15A TMEM132E

6.23e-041132731152
GeneFamilyCollagens

COL5A1 COL11A2

2.13e-0346272490
GeneFamilyFibronectin type III domain containing

NFASC MYBPC2

2.36e-02160272555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

NFASC MYBPC2

2.39e-02161272593
CoexpressionNABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS

COL5A1 LTBP2 COL11A2

5.91e-0629323MM17055
CoexpressionDAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP

PCSK5 MYCN COL5A1 PRKCA NFASC

1.44e-05258325M4680
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

MYCN COL5A1 SASH1 SLC44A5 ZBTB7B SKAP2 SH3PXD2A KREMEN2

3.38e-051074328M1941
CoexpressionESC_V6.5_UP_EARLY.V1_UP

RPRD2 SCAP SASH1 RYR3

4.86e-05166324M2770
CoexpressionGSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP

UBR1 COL11A2 ATP8A1 SH3PXD2A

9.81e-05199324M9255
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13C CDH20 SASH1 SLC44A5 RYR3

1.47e-071733252e35bf2b5534a289d93a09faae660f665c131062
ToppCellInfluenza_Severe-CD4+_T_naive|World / Disease group and Cell class

PRKCA CDH20 MYO15A TMEM132E

3.86e-06149324ce6552063510aa3e0b9d6e5b531eea67410e7056
ToppCellInfluenza_Severe-CD4+_T_naive|Influenza_Severe / Disease group and Cell class

PRKCA CDH20 MYO15A TMEM132E

4.76e-06157324287bdc4e455cd0160261a93d13538e0def49fcd4
ToppCellsevere_influenza-CD4+_T_naive|World / disease group, cell group and cell class (v2)

PRKCA CDH20 MYO15A TMEM132E

4.88e-061583248ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_AIM2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CDH20 SASH1 SLC44A5 RYR3

6.07e-061673244c8bb68ee2bf7b794940b34df96f38f3f69507e9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC13C LTBP2 GTF2I ATP8A1

8.71e-061833242f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13C CDH20 TMEM132E RYR3

8.90e-06184324658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRKCA UNC13C CDH20 TMEM132E

1.01e-051903241bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NFASC LTBP2 SH3PXD2A

1.03e-0519132404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PCSK5 COL5A1 LTBP2 SASH1

1.05e-0519232460b1312e84f6d6448365a952469c506c00b5fe93
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 COL5A1 NFASC LTBP2

1.19e-05198324bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_T_naive|Influenza_Severe / Disease, condition lineage and cell class

PRKCA CDH20 MYO15A TMEM132E

1.24e-052003240382f8fc27d18003761725e714beb6b3f3150057
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Acinar_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

PRKCA LTBP2 TMEM132E

1.10e-041303230219d0d5d21df08f816569c7eb34f1bfa095d29a
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 COL5A1 RYR3

1.15e-0413232366ec5a06eece27c0aafb548f51db9fee595e71bc
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCSK5 KREMEN2 RYR3

1.49e-0414432308005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellCOPD-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

MYCN COL5A1 LTBP2

1.96e-041583238f66979e92f886d86cecbd26aaa0c5915c049734
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 COL5A1 UNC13C

1.96e-04158323f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 COL5A1 UNC13C

1.96e-041583238c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

COL5A1 COL11A2 SH3PXD2A

2.03e-04160323ab769516f9f7798d1390ef215caf22a2d3d53e63
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL5A1 LCAT TOP1MT

2.03e-041603238a4746463ca1976f7d6de803496c851249ced797
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 MYO15A SH3PXD2A

2.03e-041603230544bc465af208da448858d6e174ff56f2e08a46
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

NFASC LTBP2 RYR3

2.07e-0416132364891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNC13C LTBP2 ATP8A1

2.10e-0416232336ddebe3bb172c992739353b7b049b2dde98b559
ToppCelldroplet-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SKAP2 RYR3

2.26e-04166323c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCelldroplet-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SKAP2 RYR3

2.26e-0416632394c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL5A1 LTBP2 CDH20

2.30e-04167323f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 COL5A1 LTBP2

2.34e-041683234b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

NFASC LTBP2 SASH1

2.38e-04169323e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13C LTBP2 RYR3

2.38e-0416932312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRKCA GTF2I KREMEN2

2.43e-04170323d74fbd995a8a37fc237f7147d398357b811d6452
ToppCelldroplet-Spleen-nan-3m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP2 SASH1 RYR3

2.47e-041713235b74df72e36ad04dfb25c72f1ca8efe043f6cda6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 NFASC LTBP2

2.47e-041713235d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCelldroplet-Spleen-nan-18m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SKAP2 RYR3

2.47e-041713234a2e6ea9674bf23e8012ef0bb2bf19ce1f55fcd5
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRKCA CDH20 RYR3

2.47e-041713235885e69e997cc2f6a27afebfe57001ca0ac062a6
ToppCelldroplet-Spleen-nan-18m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SKAP2 RYR3

2.51e-04172323850e4c9e9003807c19695be4b13121b0808a9389
ToppCelldroplet-Spleen-nan-18m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SKAP2 RYR3

2.51e-04172323018d8160cfcb7882475620dc678f48a69a0f643e
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCA GTF2I KREMEN2

2.51e-04172323f320813177f246926bfd5862b4e0f9bd828cebab
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCA GTF2I KREMEN2

2.51e-04172323b3c12a4bb08ce931de6fe800b605f3e43adea0b5
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL5A1 UNC13C LTBP2

2.55e-041733231f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCN PRKCA ATP8A1

2.55e-041733235d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCN PRKCA ATP8A1

2.60e-041743239eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRKCA GTF2I KREMEN2

2.60e-04174323262d14b42bc5ec2c8d5f33a1a0eb49a8e38dd0f0
ToppCellICU-SEP-Myeloid-cDC2|ICU-SEP / Disease, Lineage and Cell Type

TOP1MT ZC3H4 SH3PXD2A

2.64e-04175323c44fd1cc827296de7300d4a60399bb945089a170
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO15A KREMEN2 RPRD1B

2.64e-04175323f5451c29c487b998778e50349b3d774d5e20fd28
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NFASC LTBP2

2.64e-04175323795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 SASH1 SLC44A5

2.69e-04176323327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UNC13C LTBP2 ALPG

2.73e-04177323d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL5A1 LTBP2 RPRD1B

2.78e-04178323edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL5A1 NFASC LTBP2

2.82e-0417932310fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL5A1 UNC13C LTBP2

2.87e-0418032301f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellThalamus-Macroglia|Thalamus / BrainAtlas - Mouse McCarroll V32

COL11A2 LCAT CDH20

2.91e-041813234f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

COL5A1 COL11A2 SH3PXD2A

2.91e-0418132356ae86072858c156681507aecd1bc6cb0a3372d2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 SASH1 SLC44A5

2.91e-041813236956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL5A1 UNC13C LTBP2

2.91e-04181323d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellB_cell_maturation-immature_B_cell|World / Lineage and Cell class

ATP8A1 KREMEN2 MYBPC2

2.96e-041823232c7c51ebc4125d8a33454ffee0b143579ce5e451
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

PCSK5 COL5A1 LTBP2

3.01e-04183323de08f9ea02b7244d5a8788064631d10f06565337
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13C MYO15A RYR3

3.06e-04184323ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellCerebellum-Macroglia|Cerebellum / BrainAtlas - Mouse McCarroll V32

COL11A2 LCAT CDH20

3.06e-0418432391b047a01d2cad231308279ca37fa699630f7864
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13C MYO15A RYR3

3.06e-041843232cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13C MYO15A RYR3

3.06e-041843232b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 SASH1 SLC44A5

3.06e-04184323da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

COL5A1 LTBP2 SH3PXD2A

3.06e-041843230b336489c10e8c3c957795dd845454f03404382b
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

COL5A1 COL11A2 SH3PXD2A

3.06e-04184323684d05340a3dfb8aa08b881516a37f9627a10448
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PCSK5 COL5A1 LTBP2

3.11e-04185323427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL5A1 LTBP2 RYR3

3.11e-04185323e58a009aaf342be019a909747b1895d5987d4daf
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

COL5A1 LTBP2 SH3PXD2A

3.16e-041863231e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 PRKCA SH3PXD2A

3.16e-04186323de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 PRKCA SH3PXD2A

3.16e-041863230b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 SLC44A5 SKAP2

3.16e-04186323f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PCSK5 COL5A1 LTBP2

3.21e-041873234ea486991f66c29728d127171a07b81404ec0b78
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL5A1 UNC13C LTBP2

3.21e-04187323c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

COL5A1 LTBP2 SH3PXD2A

3.21e-04187323a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

COL5A1 NFASC LTBP2

3.21e-0418732392d468dde81125d51daf7abd4703741abe1ab91c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 SLC44A5 SKAP2

3.26e-04188323af740fa78542438fdff627ea1f74f4eee43316be
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL5A1 LTBP2 RPRD1B

3.26e-0418832314bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL5A1 LTBP2 RYR3

3.26e-041883234d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

COL5A1 UNC13C LTBP2

3.31e-0418932344e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LTBP2 KREMEN2 RYR3

3.31e-04189323da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

MYCN COL5A1 RYR3

3.31e-041893232157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRKCA NFASC

3.31e-04189323c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NFASC LTBP2

3.36e-041903232e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

COL5A1 LTBP2 RYR3

3.36e-04190323645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

COL5A1 NFASC LTBP2

3.36e-041903233a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRKCA NFASC

3.36e-04190323445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRKCA NFASC

3.36e-041903232e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NFASC LTBP2

3.36e-041903230028f886c789ba238c031eae5d96acaed4af8c25
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCA SCAP GTF2I

3.41e-041913234187f31ec399b4c7c3608e94e3c32b7a54b1c3d4
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PCSK5 NFASC LTBP2

3.41e-041913231726add3f392a061536b7aff72ba84303f4a0b1f
ToppCelldroplet-Marrow-BM-1m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCA SCAP GTF2I

3.41e-041913238e8bc200524a44ebe132f823ab7c15dac65d4952
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL5A1 NFASC LTBP2

3.41e-041913236688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 PRKCA NFASC

3.41e-04191323806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PCSK5 NFASC LTBP2

3.41e-04191323e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL5A1 NFASC LTBP2

3.46e-0419232399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

COL11A2 SASH1 SH3PXD2A

3.52e-04193323b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL5A1 LTBP2 SASH1

3.52e-04193323dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

COL11A2 SASH1 SH3PXD2A

3.52e-04193323e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NFASC LTBP2

3.52e-04193323dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 COL5A1 SASH1

3.52e-0419332385faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 COL5A1 SASH1

3.52e-04193323f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NFASC LTBP2

3.52e-04193323e2ee077fd381bd906e6b4329f22e7d106e422a7f
DiseaseNonsyndromic Deafness

COL11A2 MYO15A TMEM132E

9.33e-0581323C3711374
Diseasetestosterone measurement

UBR1 PRKCA GTF2I MYO15A ZBTB7B ZC3H4 SH3PXD2A

3.60e-041275327EFO_0004908
Diseasealcohol use disorder (implicated_via_orthology)

PRKCA UNC13C RYR3

1.22e-03195323DOID:1574 (implicated_via_orthology)
Diseasesevere acute respiratory syndrome, COVID-19

PRKCA NFASC UNC13C LTBP2

1.34e-03447324EFO_0000694, MONDO_0100096
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

COL11A2 MYO15A

1.41e-0351322cv:CN043650
Diseasecytokine measurement

PCSK5 UNC13C SASH1 SKAP2

1.50e-03461324EFO_0004873
DiseaseFEV/FEC ratio

PCSK5 LTBP2 GTF2I MYO15A SKAP2 SH3PXD2A

1.83e-031228326EFO_0004713
Diseaseintraocular pressure measurement

PCSK5 COL5A1 LTBP2 SH3PXD2A

2.15e-03509324EFO_0004695

Protein segments in the cluster

PeptideGeneStartEntry
YGHVPEPEDYGCSPD

ATP8A1

431

Q9Y2Q0
GGGDEAIYPPEVPYF

MYO15A

386

Q9UKN7
EDPTDDYGTEDYAGP

PCSK5

621

Q92824
EYGEGGTDPPEGPYD

COL11A2

331

P13942
PQGVIYSPDFPDEYG

KREMEN2

226

Q8NCW0
TPDPEYPDDYSQGGT

ALPG

231

P10696
PEPESVIGYSGEDYP

NFASC

811

O94856
EDVDEPPVFEPGFYF

CDH20

381

Q9HBT6
DPNPDEYYTEGDGEG

COL5A1

256

P20908
EYPYYEDPEDLGKEP

COL5A1

276

P20908
PYDDLTYGEGEENPD

COL5A1

351

P20908
PDGAPFYNYLGPEDT

LTBP2

1671

Q14767
PYTDPVGVLYEDGDD

LCAT

356

P04180
DFGDPRTYDPDFKGP

SLC44A5

16

Q8NCS7
PEDFYVEGLPEGVPF

GTF2I

766

P78347
EDYRDFEYSGPPPSA

RPRD2

831

Q5VT52
GELPCDDYGYAPPET

SCAP

751

Q12770
PDPGPCGETYEDFDT

MRPS5

206

P82675
EEDDDYPGSYSPQDP

RPRD1B

156

Q9NQG5
DEEDPTYDYPGPSQP

TMEM132E

816

Q6IEE7
EEGEYYNVPIPEGDE

PRKCA

281

P17252
DGEEYDDPFAGPPDT

SKAP2

71

O75563
GPQSYEPYEGEEEEE

ZBTB7B

266

O15156
ETPYETPQDEGYDGP

UNC13C

911

Q8NB66
DEDDFYFGGPDSTPP

MYCN

31

P04198
GDEIEDPAGDPYEMY

RYR3

4731

Q15413
PEYDIPAFGFDSEPE

SH3PXD2A

556

Q5TCZ1
PYEPLPDGVRFFYEG

TOP1MT

66

Q969P6
AYPAPYLDEYGETDP

UBR1

1686

Q8IWV7
SEDGDDEEPPYRGPF

SASH1

541

O94885
EDYGHYEELPGEPGE

ZC3H4

716

Q9UPT8
PEPPDTYEEDGGVYF

ZSWIM8

661

A7E2V4
YLFDGAEPGPPYTTD

SMARCA5

461

O60264
RPEDEGDYTFVPDGY

MYBPC2

501

Q14324