Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontype I transforming growth factor beta receptor binding

SMAD6 SMAD7

1.76e-0513102GO:0034713
GeneOntologyMolecularFunctionactivin receptor binding

SMAD6 SMAD7

2.05e-0514102GO:0070697
GeneOntologyMolecularFunctionI-SMAD binding

SMAD6 SMAD7

3.06e-0517102GO:0070411
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase binding

SMAD6 SMAD7

7.87e-0527102GO:0070696
GeneOntologyMolecularFunctiontransforming growth factor beta receptor binding

SMAD6 SMAD7

1.04e-0431102GO:0005160
GeneOntologyMolecularFunctionreceptor serine/threonine kinase binding

SMAD6 SMAD7

1.33e-0435102GO:0033612
GeneOntologyMolecularFunctiontranscription regulator inhibitor activity

SMAD6 SMAD7

1.41e-0436102GO:0140416
GeneOntologyMolecularFunctionSMAD binding

SMAD6 SMAD7

8.07e-0486102GO:0046332
GeneOntologyMolecularFunctionphospholipid binding

DYSF MYO1G MYOF

2.14e-03548103GO:0005543
GeneOntologyMolecularFunctioncalcium ion binding

DYSF MYOF PPEF2

5.18e-03749103GO:0005509
GeneOntologyMolecularFunctioncytokine receptor binding

SMAD6 SMAD7

1.08e-02324102GO:0005126
GeneOntologyMolecularFunctionlipid binding

DYSF MYO1G MYOF

1.12e-02988103GO:0008289
GeneOntologyMolecularFunctionubiquitin protein ligase binding

SMAD6 SMAD7

1.17e-02337102GO:0031625
GeneOntologyMolecularFunctionubiquitin-like protein ligase binding

SMAD6 SMAD7

1.31e-02358102GO:0044389
GeneOntologyBiologicalProcessT-tubule organization

DYSF MYOF

7.60e-069102GO:0033292
GeneOntologyBiologicalProcessnegative regulation of activin receptor signaling pathway

SMAD6 SMAD7

4.42e-0521102GO:0032926
GeneOntologyBiologicalProcessglycerol metabolic process

DYSF MYOF

4.86e-0522102GO:0006071
GeneOntologyBiologicalProcessnegative regulation of peptidyl-threonine phosphorylation

SMAD7 PPEF2

5.81e-0524102GO:0010801
GeneOntologyBiologicalProcessalditol metabolic process

DYSF MYOF

6.83e-0526102GO:0019400
GeneOntologyBiologicalProcessregulation of activin receptor signaling pathway

SMAD6 SMAD7

1.04e-0432102GO:0032925
GeneOntologyBiologicalProcessplasma membrane repair

DYSF MYOF

1.18e-0434102GO:0001778
GeneOntologyBiologicalProcessnegative regulation of SMAD protein signal transduction

SMAD6 SMAD7

1.55e-0439102GO:0060392
GeneOntologyBiologicalProcessmuscle cell development

DYSF SMAD6 MYOF

2.20e-04259103GO:0055001
GeneOntologyBiologicalProcessnegative regulation of ossification

SMAD6 SMAD7

2.56e-0450102GO:0030279
GeneOntologyBiologicalProcessregulation of peptidyl-threonine phosphorylation

SMAD7 PPEF2

2.77e-0452102GO:0010799
GeneOntologyBiologicalProcessactivin receptor signaling pathway

SMAD6 SMAD7

3.69e-0460102GO:0032924
GeneOntologyBiologicalProcessmuscle structure development

DYSF SMAD6 SMAD7 MYOF

5.11e-04858104GO:0061061
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

SMAD6 SMAD7

6.55e-0480102GO:0030514
GeneOntologyBiologicalProcessnegative regulation of protein ubiquitination

DYSF SMAD7

7.74e-0487102GO:0031397
GeneOntologyBiologicalProcesscardiac septum morphogenesis

SMAD6 SMAD7

8.10e-0489102GO:0060411
GeneOntologyBiologicalProcessregulation of SMAD protein signal transduction

SMAD6 SMAD7

8.28e-0490102GO:0060390
GeneOntologyBiologicalProcessventricular septum development

SMAD6 SMAD7

8.47e-0491102GO:0003281
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

SMAD6 SMAD7 MYOF

8.55e-04412103GO:0090287
GeneOntologyBiologicalProcessnegative regulation of protein modification by small protein conjugation or removal

DYSF SMAD7

1.02e-03100102GO:1903321
GeneOntologyBiologicalProcessnegative regulation of post-translational protein modification

DYSF SMAD7

1.10e-03104102GO:1901874
GeneOntologyBiologicalProcessureteric bud development

SMAD6 SMAD7

1.17e-03107102GO:0001657
GeneOntologyBiologicalProcessSMAD protein signal transduction

SMAD6 SMAD7

1.23e-03110102GO:0060395
GeneOntologyBiologicalProcessmesonephric tubule development

SMAD6 SMAD7

1.23e-03110102GO:0072164
GeneOntologyBiologicalProcessmesonephric epithelium development

SMAD6 SMAD7

1.23e-03110102GO:0072163
GeneOntologyBiologicalProcessmesonephros development

SMAD6 SMAD7

1.30e-03113102GO:0001823
GeneOntologyBiologicalProcesspeptidyl-threonine phosphorylation

SMAD7 PPEF2

1.35e-03115102GO:0018107
GeneOntologyBiologicalProcessregulation of neurotransmitter secretion

DYSF MYOF

1.42e-03118102GO:0046928
GeneOntologyBiologicalProcesspolyol metabolic process

DYSF MYOF

1.54e-03123102GO:0019751
GeneOntologyBiologicalProcesspeptidyl-threonine modification

SMAD7 PPEF2

1.59e-03125102GO:0018210
GeneOntologyBiologicalProcessnegative regulation of protein modification process

DYSF SMAD7 PPEF2

1.60e-03512103GO:0031400
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

SMAD6 SMAD7

1.74e-03131102GO:0030510
GeneOntologyBiologicalProcessmuscle cell differentiation

DYSF SMAD6 MYOF

1.78e-03531103GO:0042692
GeneOntologyBiologicalProcessartery development

SMAD6 SMAD7

1.80e-03133102GO:0060840
GeneOntologyBiologicalProcesscardiac septum development

SMAD6 SMAD7

1.82e-03134102GO:0003279
GeneOntologyBiologicalProcessnegative regulation of transforming growth factor beta receptor signaling pathway

SMAD6 SMAD7

1.93e-03138102GO:0030512
GeneOntologyBiologicalProcessregulation of neurotransmitter transport

DYSF MYOF

2.01e-03141102GO:0051588
GeneOntologyBiologicalProcessregulation of ossification

SMAD6 SMAD7

2.19e-03147102GO:0030278
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

SMAD6 SMAD7

2.28e-03150102GO:0090288
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

SMAD6 SMAD7

2.62e-03161102GO:0003206
GeneOntologyBiologicalProcesscardiac ventricle development

SMAD6 SMAD7

2.62e-03161102GO:0003231
GeneOntologyBiologicalProcesskidney epithelium development

SMAD6 SMAD7

2.65e-03162102GO:0072073
GeneOntologyBiologicalProcessT cell mediated immunity

MYO1G SMAD7

2.68e-03163102GO:0002456
GeneOntologyBiologicalProcessblood circulation

SMAD6 SMAD7 MYOF

3.14e-03648103GO:0008015
GeneOntologyBiologicalProcessplasma membrane organization

DYSF MYOF

3.54e-03188102GO:0007009
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

SMAD6 SMAD7

3.69e-03192102GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

SMAD6 SMAD7

3.81e-03195102GO:1903844
GeneOntologyBiologicalProcesssignal release from synapse

DYSF MYOF

3.81e-03195102GO:0099643
GeneOntologyBiologicalProcessneurotransmitter secretion

DYSF MYOF

3.81e-03195102GO:0007269
GeneOntologyBiologicalProcessBMP signaling pathway

SMAD6 SMAD7

3.88e-03197102GO:0030509
GeneOntologyBiologicalProcessmembrane fusion

DYSF MYOF

4.44e-03211102GO:0061025
GeneOntologyBiologicalProcesscirculatory system process

SMAD6 SMAD7 MYOF

4.45e-03733103GO:0003013
GeneOntologyBiologicalProcesscardiac chamber development

SMAD6 SMAD7

4.48e-03212102GO:0003205
GeneOntologyBiologicalProcessresponse to BMP

SMAD6 SMAD7

4.61e-03215102GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

SMAD6 SMAD7

4.61e-03215102GO:0071773
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

SMAD6 SMAD7

4.73e-03218102GO:0090101
GeneOntologyBiologicalProcessregulation of protein ubiquitination

DYSF SMAD7

5.08e-03226102GO:0031396
GeneOntologyBiologicalProcessnegative regulation of intracellular signal transduction

SMAD6 SMAD7 PPEF2

5.59e-03795103GO:1902532
GeneOntologyBiologicalProcessblood vessel morphogenesis

DYSF SMAD6 SMAD7

6.03e-03817103GO:0048514
GeneOntologyCellularComponentheteromeric SMAD protein complex

SMAD6 SMAD7

5.76e-068102GO:0071144
GeneOntologyCellularComponentSMAD protein complex

SMAD6 SMAD7

9.25e-0610102GO:0071141
GeneOntologyCellularComponentcentriolar satellite

DYSF MYOF

1.62e-03128102GO:0034451
GeneOntologyCellularComponentexocytic vesicle membrane

DYSF MYOF

3.14e-03179102GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

DYSF MYOF

3.14e-03179102GO:0030672
GeneOntologyCellularComponentcentrosome

DYSF SMAD7 MYOF

4.92e-03770103GO:0005813
GeneOntologyCellularComponentlamellipodium

DYSF MYO1G

5.12e-03230102GO:0030027
MousePhenoskeletal muscle fiber degeneration

DYSF MYOF

9.60e-0521102MP:0009412
MousePhenoskeletal muscle degeneration

DYSF MYOF

1.98e-0430102MP:0009415
MousePhenotransposition of great arteries

SMAD6 SMAD7

4.89e-0447102MP:0004110
MousePhenomuscle degeneration

DYSF MYOF

6.70e-0455102MP:0000749
DomainFerA

DYSF MYOF

7.74e-073102SM01200
DomainFerlin_A-domain

DYSF MYOF

7.74e-073102IPR012560
DomainFerA

DYSF MYOF

7.74e-073102PF08165
DomainPeroxin/Ferlin

DYSF MYOF

1.55e-064102IPR006614
DomainDysFC

DYSF MYOF

1.55e-064102SM00694
DomainDysFN

DYSF MYOF

1.55e-064102SM00693
DomainFerI

DYSF MYOF

2.58e-065102SM01202
DomainFerB

DYSF MYOF

2.58e-065102SM01201
DomainFerIin_dom

DYSF MYOF

2.58e-065102IPR012968
DomainFerlin_B-domain

DYSF MYOF

2.58e-065102IPR012561
DomainFerI

DYSF MYOF

2.58e-065102PF08151
DomainFerB

DYSF MYOF

2.58e-065102PF08150
DomainFerlin_C

DYSF MYOF

2.58e-065102PF16165
DomainFerlin_C

DYSF MYOF

2.58e-065102IPR032362
DomainDwarfin

SMAD6 SMAD7

7.21e-068102IPR013790
Domain-

SMAD6 SMAD7

7.21e-0681023.90.520.10
DomainMAD_homology_MH1

SMAD6 SMAD7

7.21e-068102IPR013019
DomainMH2

SMAD6 SMAD7

7.21e-068102PS51076
DomainMH1

SMAD6 SMAD7

7.21e-068102PS51075
DomainMH2

SMAD6 SMAD7

7.21e-068102PF03166
DomainSMAD_dom_Dwarfin-type

SMAD6 SMAD7

7.21e-068102IPR001132
DomainDWB

SMAD6 SMAD7

7.21e-068102SM00524
DomainMH1

SMAD6 SMAD7

1.70e-0512102PF03165
DomainMAD_homology1_Dwarfin-type

SMAD6 SMAD7

1.70e-0512102IPR003619
DomainDWA

SMAD6 SMAD7

1.70e-0512102SM00523
DomainSMAD_dom-like

SMAD6 SMAD7

3.08e-0516102IPR017855
Domain-

SMAD6 SMAD7

3.08e-05161022.60.200.10
DomainSMAD_FHA_domain

SMAD6 SMAD7

3.37e-0452102IPR008984
DomainC2

DYSF MYOF

2.12e-03131102PF00168
DomainC2

DYSF MYOF

2.31e-03137102SM00239
DomainC2

DYSF MYOF

2.48e-03142102PS50004
Domain-

DYSF MYOF

2.69e-031481022.60.40.150
DomainC2_dom

DYSF MYOF

3.29e-03164102IPR000008
PathwayREACTOME_SIGNALING_BY_BMP

SMAD6 SMAD7

1.30e-043182M1662
PathwayREACTOME_SIGNALING_BY_BMP

SMAD6 SMAD7

1.30e-043182MM14789
PathwayPID_BMP_PATHWAY

SMAD6 SMAD7

2.40e-044282M181
PathwayWP_TGFBETA_SIGNALING_PATHWAY

SMAD6 SMAD7

3.83e-045382MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

SMAD6 SMAD7

4.12e-045582M39351
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

SMAD6 SMAD7

4.74e-045982M39886
PathwayWP_APOPTOSIS

SCAF11 HRK

9.37e-048382MM15972
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

SMAD6 SMAD7

1.01e-038682M2642
PathwayWP_APOPTOSIS

SCAF11 HRK

1.05e-038882M39654
PathwayWP_COMPREHENSIVE_IL17A_SIGNALING

SMAD6 SMAD7

1.64e-0311082MM16642
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

SMAD6 SMAD7

1.82e-0311682MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

SMAD6 SMAD7

1.85e-0311782M39530
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

SMAD6 SMAD7

1.88e-0311882MM15588
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

SMAD6 SMAD7

3.47e-0316182M27871
Pubmed

Prognostic value of the expression of Smad6 and Smad7, as inhibitory Smads of the TGF-beta superfamily, in esophageal squamous cell carcinoma.

SMAD6 SMAD7

7.44e-08210215736400
Pubmed

Inhibitory Smad proteins promote the differentiation of mouse embryonic stem cells into ependymal-like ciliated cells.

SMAD6 SMAD7

7.44e-08210220807502
Pubmed

Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b.

DYSF MYOF

7.44e-08210218495154
Pubmed

Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains.

DYSF MYOF

7.44e-08210211959863
Pubmed

Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin.

DYSF MYOF

7.44e-08210231004665
Pubmed

Inhibitory SMADs: potential regulators of ovarian function.

SMAD6 SMAD7

7.44e-08210225550343
Pubmed

Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells.

SMAD6 SMAD7

7.44e-08210215033458
Pubmed

Loss of dysferlin or myoferlin results in differential defects in excitation-contraction coupling in mouse skeletal muscle.

DYSF MYOF

7.44e-08210234354129
Pubmed

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.

SMAD6 SMAD7

7.44e-08210217934461
Pubmed

While dysferlin and myoferlin are coexpressed in the human placenta, only dysferlin expression is responsive to trophoblast fusion in model systems.

DYSF MYOF

7.44e-08210219228595
Pubmed

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis.

SMAD6 SMAD7

7.44e-08210220658468
Pubmed

Inhibitory smads and tgf-Beta signaling in glomerular cells.

SMAD6 SMAD7

2.23e-07310212397035
Pubmed

FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins.

DYSF MYOF

2.23e-07310230026467
Pubmed

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling.

SMAD6 SMAD7

2.23e-07310212118366
Pubmed

Minor contribution of SMAD7 and KLF10 variants to genetic susceptibility of type 2 diabetes.

SMAD6 SMAD7

2.23e-07310217931948
Pubmed

Genetic susceptibility to keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans.

SMAD6 SMAD7

2.23e-07310218445023
Pubmed

Dysferlin and myoferlin regulate transverse tubule formation and glycerol sensitivity.

DYSF MYOF

2.23e-07310224177035
Pubmed

Hsa-miR-186-5p regulates TGFβ signaling pathway through expression suppression of SMAD6 and SMAD7 genes in colorectal cancer.

SMAD6 SMAD7

2.23e-07310233938174
Pubmed

The C2 domains of otoferlin, dysferlin, and myoferlin alter the packing of lipid bilayers.

DYSF MYOF

2.23e-07310223859474
Pubmed

Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin.

DYSF MYOF

2.23e-07310237434585
Pubmed

Bone morphogenetic protein and transforming growth factor beta inhibitory Smads 6 and 7 are expressed in human adult normal and osteoarthritic cartilage in vivo and are differentially regulated in vitro by interleukin-1beta.

SMAD6 SMAD7

2.23e-07310215529348
Pubmed

Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma.

SMAD6 SMAD7

4.46e-07410220514018
Pubmed

AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.

DYSF MYOF

4.46e-07410217185750
Pubmed

Smad6 inhibits signalling by the TGF-beta superfamily.

SMAD6 SMAD7

4.46e-0741029335505
Pubmed

Modulation of thrombomodulin-dependent activation of human protein C through differential expression of endothelial Smads.

SMAD6 SMAD7

4.46e-07410212407115
Pubmed

Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7.

SMAD6 SMAD7

4.46e-07410211737269
Pubmed

Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling.

SMAD6 SMAD7

7.44e-07510211231077
Pubmed

FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor.

SMAD6 SMAD7

7.44e-07510216720724
Pubmed

Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads.

SMAD6 SMAD7

7.44e-07510211483516
Pubmed

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.

SMAD6 SMAD7

7.44e-07510215817471
Pubmed

Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.

DYSF MYOF

7.44e-07510224687993
Pubmed

Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways.

SMAD6 SMAD7

1.12e-06610218644788
Pubmed

Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6.

SMAD6 SMAD7

1.12e-06610223455153
Pubmed

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium.

SMAD6 SMAD7

1.12e-0661029256479
Pubmed

SMAD expression in the testis: an insight into BMP regulation of spermatogenesis.

SMAD6 SMAD7

1.12e-06610218069690
Pubmed

Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.

SMAD6 SMAD7

1.12e-06610222960056
Pubmed

Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3.

SMAD6 SMAD7

1.56e-06710212815042
Pubmed

STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling.

SMAD6 SMAD7

1.56e-06710210757800
Pubmed

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.

SMAD6 SMAD7

1.56e-06710210376010
Pubmed

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7.

SMAD6 SMAD7

1.56e-06710214657019
Pubmed

Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

SMAD6 SMAD7

2.08e-06810210647776
Pubmed

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

SMAD6 SMAD7

2.08e-06810211278251
Pubmed

Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.

SMAD6 SMAD7

2.08e-06810220663871
Pubmed

TGF-beta signaling by Smad proteins.

SMAD6 SMAD7

2.08e-06810210708949
Pubmed

The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.

SMAD6 SMAD7

2.08e-06810215359284
Pubmed

TGF-beta signal transduction.

SMAD6 SMAD7

2.68e-0691029759503
Pubmed

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.

SMAD6 SMAD7

2.68e-06910226555259
Pubmed

Holding their own: the noncanonical roles of Smad proteins.

SMAD6 SMAD7

2.68e-06910219018011
Pubmed

The Smad pathway.

SMAD6 SMAD7

2.68e-06910210708948
Pubmed

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.

SMAD6 SMAD7

2.68e-06910215496141
Pubmed

Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.

SMAD6 SMAD7

2.68e-06910216601693
Pubmed

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).

SMAD6 SMAD7

3.34e-061010215221015
Pubmed

Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.

SMAD6 SMAD7

3.34e-061010223620745
Pubmed

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor.

SMAD6 SMAD7

3.34e-06101029436979
Pubmed

Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.

SMAD6 SMAD7

3.34e-061010216890162
Pubmed

Human BAMBI cooperates with Smad7 to inhibit transforming growth factor-beta signaling.

SMAD6 SMAD7

4.09e-061110219758997
Pubmed

Smad expression during kidney development.

SMAD6 SMAD7

4.90e-061210214656760
Pubmed

TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs.

SMAD6 SMAD7

5.79e-061310218095342
Pubmed

Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3.

SMAD6 SMAD7

6.76e-061410211854453
Pubmed

The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation.

SMAD6 SMAD7

6.76e-061410212149478
Pubmed

TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity.

SMAD6 SMAD7

6.76e-061410221791611
Pubmed

Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells.

SMAD6 SMAD7

6.76e-061410226952187
Pubmed

The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.

SMAD6 SMAD7

8.91e-061610221907140
Pubmed

p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.

SMAD6 SMAD7

1.14e-051810219717565
Pubmed

Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension.

SMAD6 SMAD7

1.56e-052110223610558
Pubmed

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.

SMAD6 SMAD7

1.71e-052210224850914
Pubmed

Bone morphogenetic proteins.

SMAD6 SMAD7

1.88e-052310215621726
Pubmed

Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.

DYSF MYOF

2.80e-052810226884322
Pubmed

SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.

SMAD6 SMAD7

3.01e-052910234822715
Pubmed

N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation.

SMAD6 SMAD7

3.22e-053010220534673
Pubmed

An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.

SMAD6 SMAD7

4.40e-053510218832392
InteractionBAMBI interactions

SMAD6 SMAD7

2.32e-0515102int:BAMBI
InteractionRIPOR2 interactions

DYSF MYOF

2.32e-0515102int:RIPOR2
InteractionPIAS4 interactions

SMAD6 SMAD7 ZNF445

7.14e-05173103int:PIAS4
InteractionSMAD6 interactions

SMAD6 SMAD7

3.36e-0456102int:SMAD6
GeneFamilyFerlin family

DYSF MYOF

4.13e-066102828
GeneFamilySMAD family

SMAD6 SMAD7

7.70e-068102750
CoexpressionGAUTSCHI_SRC_SIGNALING

SMAD6 SMAD7

3.66e-068102M14722
CoexpressionGSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP

SCAF11 SMAD6 SMAD7

5.05e-05200103M4545
CoexpressionHALMOS_CEBPA_TARGETS_DN

SMAD6 SMAD7

1.29e-0445102M8604
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_ARTERIAL_ENDOTHELIAL_CELL

SMAD6 SMAD7 MYOF

1.46e-04286103M45746
CoexpressionHALLMARK_TGF_BETA_SIGNALING

SMAD6 SMAD7

1.85e-0454102M5896
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1 PPEF2

6.69e-06174103197686570cec6d96a92e77e6409325d3bfe6f991
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1 PPEF2

6.69e-061741032eee7b5471672b439f95eba11494c2adf8cb7006
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6 ASTN1

7.65e-06182103f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DYSF SMAD6 SMAD7

9.55e-06196103915e4a7422058be246b54760df31e8a607310625
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SMAD6 SMAD7

9.70e-06197103c29ed0e706999d4c2b93e6e3bf46c42aeceb4813
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DYSF SMAD6 SMAD7

9.85e-06198103002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SMAD6 SMAD7 PPEF2

9.85e-06198103f88198e11e835ad53d339c312f8f7b7b0b5c02d3
ToppCellInfluenza|World / Disease, condition lineage and cell class

DYSF MYO1G MYOF

1.01e-05200103df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

DYSF PPEF2

1.16e-0473102cc89c94a3768b02036757dea86989d9284b214b9
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

DYSF PPEF2

1.16e-0473102ae80fcf3544c18fe0318a8311e96f2448f7cb03c
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2|Hippocampus / BrainAtlas - Mouse McCarroll V32

DYSF PPEF2

1.16e-04731026f28d52700bab981c8a3664ba4762f3572f7e788
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tmem163_Arhgap25|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DYSF HRK

2.98e-04117102e1a14b8413a6f4b194217a90eb2c5f95ab14522e
ToppCellmild-Myeloid-CD14_Monocytes_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SMAD6 MYOF

3.90e-041341028ba1f8d0af63bb7a802a002e72fe181b203cb451
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MYOF PPEF2

4.08e-0413710225b5370b63644351efddb8749ef174beca0581cd
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SMAD6 ASTN1

4.26e-04140102b9aeb7dda7f377b580dd8a44912f300721437387
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|343B / Donor, Lineage, Cell class and subclass (all cells)

MYO1G ZNF445

4.95e-0415110278475027bba9e3026e42493fec8ea630972353bb
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G PPEF2

5.41e-0415810290ca742739a208d457db087655ba3d1c18a9da57
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF SMAD6

5.48e-04159102d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

DYSF SMAD6

5.55e-04160102958256e3d3836160763b82bb48f794087918d935
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G PPEF2

5.55e-041601028dae9b0cf90a09acb196223f45a14680102630b2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SMAD7

5.55e-0416010233050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SMAD6 SMAD7

5.69e-0416210225bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO1G ZNF445

5.76e-041631020ab043b68e8739adcedda01165a3758cd0d22728
ToppCellB_cells-ABCs|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HRK MYO1G

5.83e-04164102f45013706a917f0f0d69c23f288128f252cd60c7
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMAD6 SMAD7

5.97e-041661027a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMAD6 SMAD7

5.97e-04166102bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPEF2 ZNF445

5.97e-0416610266026988509e39e41274fa0de738383219e8ff30
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF PPEF2

6.12e-041681022e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF SMAD6

6.19e-04169102987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G PPEF2

6.26e-04170102ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G PPEF2

6.26e-04170102a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SMAD6

6.33e-04171102b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-non-classical_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DYSF MYOF

6.41e-04172102968d18ab8c3cdeb7936a2aa721a7f41525763863
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1G ZNF445

6.41e-041721023a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1G ZNF445

6.41e-04172102cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DYSF SMAD6

6.48e-04173102b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF SMAD6

6.48e-04173102f193c63cc536d891c9d23043765e320252bb6e65
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF SMAD6

6.48e-04173102afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCellfacs-Heart-RV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1

6.63e-04175102bfac175b79bb7d3d81074a2407c206a7647ee75d
ToppCellfacs-Heart-RV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1

6.63e-04175102c94fb35bbac95123201ca87ca835aecaefc0c490
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1G PPEF2

6.63e-04175102e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6

6.71e-041761025386386619cf173939d3c117b20e6f27ab397993
ToppCellfacs-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6

6.71e-0417610292ebcea9b2b22601234b76d7a98f0410b905a87b
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

DYSF MYOF

6.71e-041761020923b01137d6f9956ca815b41102c81e82624065
ToppCellfacs-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6

6.71e-041761029ddf87e586d2378984cd007c60f7dc254845f8f3
ToppCellfacs-Pancreas-Endocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6

6.71e-04176102e987e741fcf1bed8598a5060700efd3018f8123b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF SMAD6

6.71e-04176102dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF SMAD6

6.71e-0417610264e426f5e84884ce2c29acf6f4b958962a63927f
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6

6.71e-04176102820edade963768e4bfd86b554da4cd7100567ac8
ToppCell3'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRK MYO1G

6.78e-0417710234458f1eb7f3b1fd0cb9904529c01a9ca2f15500
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DYSF SMAD6

6.78e-041771023a94ee9b58ebdbbc75e00954cf1f6922f88f8f88
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SMAD6 SMAD7

6.78e-041771025ff8dcfb030312126695d53a026d2e104a401b83
ToppCellEndothelial-Endothelial-C|Endothelial / shred on cell class and cell subclass (v4)

SMAD6 SMAD7

6.78e-04177102b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

DYSF SMAD6

6.86e-04178102ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

DYSF SMAD6

6.86e-04178102804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCelldroplet-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMAD6 SMAD7

6.94e-04179102006f2b6887b0f1f26e58bb11c919468b62bf4d62
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRK MYO1G

6.94e-04179102223f0895da89c7606f637aef113912dd06f39c5a
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6

6.94e-0417910208cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 MYOF

7.01e-0418010267c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SMAD7

7.01e-04180102755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 SMAD7

7.01e-04180102baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1

7.01e-0418010263a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1

7.01e-04180102a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 SMAD7

7.01e-041801020f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRK MYO1G

7.01e-04180102cb6b11883f42c8beff07f899036c803d786ac6a3
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 SMAD7

7.01e-041801022d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1

7.09e-04181102395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRK ASTN1

7.09e-04181102429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMAD6 SMAD7

7.09e-041811024d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DYSF SMAD6

7.09e-041811022c660fcf0404c155955b67ab2958d6e6b0e30024
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRK MYO1G

7.09e-0418110251836cdc66e42f04ed6a3c167cd6a3a67428c9f7
ToppCell11.5-Airway-Immune-Hematopoietic,_B_Cells|Airway / Age, Tissue, Lineage and Cell class

HRK MYO1G

7.09e-04181102727344d7b2953568b7b3463398c7d56878cf2c2b
ToppCellMonocytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DYSF MYO1G

7.09e-04181102d8b98c3d9bef026a0a35948219027f27718ffbee
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 MYOF

7.17e-04182102d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 SMAD7

7.17e-04182102eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 MYO1G

7.17e-04182102bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCellfacs-Heart-RA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMAD6 SMAD7

7.17e-041821028292e8e8474c930ffb88cbab4f6ebdb6f58db645
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 MYOF

7.17e-04182102c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMAD6 SMAD7

7.25e-041831023427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 SMAD7

7.25e-0418310228cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 SMAD7

7.25e-041831023fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell5'-GW_trimst-2-LymphNode-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SMAD6

7.33e-04184102df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SMAD6

7.33e-041841021ace70f12b417185bdd46042833f72b3b6815966
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 MYOF

7.33e-04184102087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DYSF SMAD6

7.33e-04184102c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellwk_08-11-Hematologic_Lymphocytic-B-Immature_B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HRK MYO1G

7.33e-04184102e6669a1b7ea7e4f8e094add5117689470019d85d
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HRK MYO1G

7.41e-041851028fc357ee041bfd588986730a52ea2021b5f88941
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DYSF SMAD6

7.41e-04185102dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCelldroplet-Lung-nan-21m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMAD6 SMAD7

7.41e-0418510243b7345a61e31099718c9cecf194b4e9884b904b
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

DYSF SMAD6

7.41e-0418510207f9f38f0739d7c830641723a38385550ac1ac92
ToppCelldroplet-Lung-21m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SMAD6 SMAD7

7.41e-041851029c907298166e3dd65b1d1e7673a1b8d01b492bd0
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

DYSF SMAD6

7.48e-04186102c6075fe84226b370c5139066793844ad33ae2db1
ToppCellThalamus-Endothelial|Thalamus / BrainAtlas - Mouse McCarroll V32

DYSF MYOF

7.48e-04186102dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SMAD6 SMAD7

7.48e-041861022d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMAD6 SMAD7

7.48e-041861024ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF SMAD7

7.56e-041871020ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCelldroplet-Kidney-nan-3m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF SMAD6

7.56e-04187102d72012e94857606f39975cf672f6b8c2e0fe093e
ToppCellNS-moderate-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO1G SMAD7

7.56e-04187102fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

DYSF SMAD6

7.56e-04187102f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HRK MYO1G

7.56e-041871029d298f43ae81d72091b31aaa6df41046d4aa31c5
Drugpasireotide

SMAD6 SMAD7

2.65e-0518102ctd:C517782
DrugSecurinine [5610-40-2]; Down 200; 18.4uM; HL60; HT_HG-U133A

SMAD6 SMAD7 MYOF

6.27e-051871032729_DN
Druggeldanamycin; Down 200; 1uM; HL60; HT_HG-U133A

SMAD6 SMAD7 MYOF

6.37e-051881036187_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7 MYOF

6.47e-051891031006_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7 MYOF

6.47e-051891031005_DN
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7 MYOF

7.10e-05195103999_DN
Drug(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A

DYSF HRK MYOF

7.21e-051961033571_UP
DrugSulfadimethoxine [122-11-2]; Up 200; 12.8uM; PC3; HT_HG-U133A

HRK ASTN1 MYOF

7.21e-051961037400_UP
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

DYSF HRK MYOF

7.54e-051991032310_DN
DrugCK2 inhibitor 2

DYSF MYOF

1.09e-0436102CID005326976
DrugMDPC

SMAD6 SMAD7

1.28e-0439102CID000032842
DrugIron Compounds

SMAD6 SMAD7

1.28e-0439102ctd:D058085
DrugOctreotide

SMAD6 SMAD7

1.48e-0442102ctd:D015282
Drug1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea

SMAD6 SMAD7

1.94e-0448102ctd:C581572
Drug3 tp

SMAD6 SMAD7

3.67e-0466102CID009549240
Druggalangin

SMAD6 SMAD7

3.89e-0468102ctd:C037032
DrugBmps

SMAD6 SMAD7

4.01e-0469102CID004620597
Drug1,3,2-dioxaborolan-2-ol

SMAD6 SMAD7

9.08e-04104102CID005289333
DrugAC1L9Q5W

SMAD6 SMAD7

9.43e-04106102CID000452221
DrugNSC350854

SMAD6 SMAD7

9.79e-04108102CID000434448
DrugAC1L1K15

SMAD6 SMAD7

1.21e-03120102CID000005293
DrugEvans blue dye

DYSF MYOF

1.35e-03127102CID005356750
Drughalofuginone

HRK SMAD7

1.35e-03127102ctd:C010176
DrugAsbestos, Crocidolite

DYSF HRK SMAD6 SMAD7

1.42e-031241104ctd:D017638
Drugmethyl ethyl ketone

SMAD6 SMAD7 ZNF445

1.79e-03587103CID000006569
DrugMW 1

SMAD6 SMAD7

1.90e-03151102CID000073965
DrugCP094

SMAD6 SMAD7

2.26e-03165102CID000086322
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.45e-031721025903_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SCAF11 MYOF

2.45e-031721027073_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SCAF11 MYOF

2.48e-031731025950_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SCAF11 MYOF

2.48e-031731024458_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.51e-031741025945_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SCAF11 SMAD7

2.51e-031741021659_DN
DrugEthaverine hydrochloride [985-13-7]; Down 200; 9.2uM; HL60; HT_HG-U133A

DYSF MYOF

2.51e-031741023037_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.54e-031751026891_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.54e-031751025935_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.57e-031761025976_DN
DrugBetulinic acid [472-15-1]; Down 200; 8.8uM; HL60; HT_HG-U133A

SMAD6 MYOF

2.57e-031761021345_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.60e-031771026434_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.60e-031771026551_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

SMAD6 MYOF

2.62e-031781024710_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SCAF11 MYOF

2.68e-031801025981_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SCAF11 MYOF

2.71e-031811027077_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7

2.74e-03182102947_DN
DrugNaftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A

DYSF HRK

2.83e-031851023536_UP
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.83e-031851025585_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7

2.86e-03186102916_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A

SCAF11 MYOF

2.86e-031861026874_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD6 SMAD7

2.89e-031871021631_DN
DrugICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.92e-031881027091_DN
Drugfluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

HRK MYOF

2.95e-031891026954_UP
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.95e-031891025578_DN
Drug0175029-0000 [211245-78-2]; Down 200; 1uM; PC3; HT_HG-U133A

SMAD6 SMAD7

2.95e-031891027392_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD6 SMAD7

2.95e-031891021643_DN
Drugradicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7

2.98e-03190102836_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD7 MYOF

2.98e-031901025586_DN
DrugCID11987713

HRK SMAD6

2.98e-03190102CID011987713
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

SMAD7 MYOF

3.01e-03191102998_DN
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

SCAF11 MYOF

3.01e-031911024168_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; HL60; HG-U133A

SMAD6 MYOF

3.01e-031911021417_UP
DrugBeta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A

HRK MYOF

3.01e-031911023890_DN
DrugProadifen hydrochloride [62-68-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A

DYSF HRK

3.01e-031911027165_UP
Drug17-AAG; Down 200; 1uM; HL60; HT_HG-U133A

SMAD6 SMAD7

3.01e-031911022678_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD6 SMAD7

3.04e-031921025222_DN
DrugAmitryptiline hydrochloride [549-18-8]; Up 200; 12.8uM; PC3; HT_HG-U133A

SMAD7 MYOF

3.04e-031921026353_UP
Drug5230742; Down 200; 17uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7

3.04e-03192102970_DN
Drug17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7

3.04e-03192102993_DN
DrugFurosemide [54-31-9]; Down 200; 12uM; MCF7; HT_HG-U133A

DYSF HRK

3.08e-031931023197_DN
DrugDilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A

SMAD7 MYOF

3.08e-031931027364_DN
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A

SMAD6 SMAD7

3.08e-031931021644_DN
DrugHymecromone [90-33-5]; Down 200; 22.8uM; PC3; HT_HG-U133A

HRK ASTN1

3.08e-031931024623_DN
DrugSertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A

DYSF MYOF

3.11e-031941026811_DN
DrugRetinoic acid [302-79-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A

SMAD6 SMAD7

3.11e-031941026243_DN
Drug5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA

HRK SMAD6

3.11e-03194102828_UP
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

SMAD6 SMAD7

3.11e-031941025914_DN
DrugH-89, Dihydrochloride; Up 200; 0.5uM; MCF7; HT_HG-U133A

DYSF HRK

3.11e-031941026878_UP
DrugAsiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A

HRK SMAD7

3.14e-031951023504_DN
DrugBudesonide [51333-22-3]; Up 200; 9.2uM; PC3; HT_HG-U133A

HRK MYOF

3.14e-031951026330_UP
DrugTetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A

HRK MYOF

3.14e-031951024412_DN
DrugBenfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A

DYSF SMAD6

3.14e-031951022621_DN
DrugPentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A

DYSF SMAD6

3.14e-031951024396_DN
Drugradicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

SMAD6 SMAD7

3.14e-03195102953_DN
DrugFamprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

DYSF MYOF

3.14e-031951023834_DN
DrugFlurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A

DYSF MYOF

3.14e-031951025269_DN
DrugBacitracin [1405-87-4]; Up 200; 2.8uM; MCF7; HT_HG-U133A

DYSF MYOF

3.14e-031951027448_UP
Drug17-DMAG; Down 200; 0.1uM; HL60; HT_HG-U133A

SMAD6 SMAD7

3.14e-031951026172_DN
DrugPrenylamine lactate [69-43-2]; Down 200; 9.6uM; PC3; HT_HG-U133A

SMAD6 MYOF

3.14e-031951025070_DN
DrugTetrandrine [518-34-3]; Down 200; 6.4uM; MCF7; HT_HG-U133A

DYSF SMAD7

3.14e-031951026082_DN
DrugEsculin Hydrate [531-75-9]; Down 200; 11.8uM; PC3; HT_HG-U133A

SMAD6 SMAD7

3.14e-031951026310_DN
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A

DYSF MYOF

3.14e-031951025241_DN
DrugDihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A

DYSF MYOF

3.14e-031951027034_UP
DrugAcetazolamide [59-66-5]; Down 200; 18uM; MCF7; HT_HG-U133A

SMAD6 SMAD7

3.17e-031961021686_DN
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA

SMAD6 MYOF

3.17e-031961021024_DN
DrugIvermectin [70288-86-7]; Down 200; 4.6uM; PC3; HT_HG-U133A

SMAD6 MYOF

3.17e-031961022051_DN
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

DYSF MYOF

2.17e-067102DOID:11724 (implicated_via_orthology)
Diseasenephritis (biomarker_via_orthology)

SMAD6 SMAD7

5.68e-0611102DOID:10952 (biomarker_via_orthology)
Diseasepulmonary hypertension (biomarker_via_orthology)

SMAD6 SMAD7

3.22e-0480102DOID:6432 (biomarker_via_orthology)
Diseasecolorectal cancer, colorectal adenoma

SMAD6 SMAD7

1.15e-03152102EFO_0005406, MONDO_0005575
Diseasehippocampal volume

HRK SMAD7

4.31e-03297102EFO_0005035
Diseasepeak expiratory flow

DYSF SMAD6

1.17e-02498102EFO_0009718
Diseaseeosinophil count

DYSF HRK SMAD7

1.18e-021488103EFO_0004842
Diseaseretinal vasculature measurement

DYSF MYOF

1.26e-02517102EFO_0010554

Protein segments in the cluster

PeptideGeneStartEntry
VMILYTRRRWCKRRR

ASTN1

171

O14525
QRRERERRTRKWSRS

SCAF11

921

Q99590
TDAFRRRRWRRRMEP

DYSF

1086

O75923
RRYVARLEMRRRCTW

PPEF2

31

O14830
QRTMWRRRARSRRAP

HRK

46

O00198
MFRSKRSGLVRRLWR

SMAD6

1

O43541
MFRTKRSALVRRLWR

SMAD7

1

O15105
RKTFRWRSNFTRHMR

ZNF445

631

P59923
RRLRAIYTIMRWFRR

MYO1G

731

B0I1T2
RSSDTFRRRRWRRKM

MYOF

1066

Q9NZM1
FRRRRWRRKMAPSET

MYOF

1071

Q9NZM1