Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sulfuric ester hydrolase activity	GALNS ARSD ARSF SGSH	2.83e-07	17	68	4	GO:0008484
GeneOntologyMolecularFunction	arylsulfatase activity	GALNS ARSD ARSF	1.34e-05	14	68	3	GO:0004065
GeneOntologyMolecularFunction	serine-type carboxypeptidase activity	SCPEP1 CPVL	1.14e-04	5	68	2	GO:0004185
GeneOntologyMolecularFunction	glutamate-gated calcium ion channel activity	GRIN2C GRIN2D	3.16e-04	8	68	2	GO:0022849
GeneOntologyMolecularFunction	NMDA glutamate receptor activity	GRIN2C GRIN2D	3.16e-04	8	68	2	GO:0004972
GeneOntologyMolecularFunction	serine-type exopeptidase activity	SCPEP1 CPVL	7.38e-04	12	68	2	GO:0070008
GeneOntologyMolecularFunction	calcium channel activity	CALHM1 CATSPER4 GRIN2C GRIN2D	9.84e-04	129	68	4	GO:0005262
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	CALHM1 CATSPER4 GRIN2C GRIN2D	1.33e-03	140	68	4	GO:0099094
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIN2C GRIN2D	1.50e-03	17	68	2	GO:0004970
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CALHM1 CATSPER4 GRIN2C GRIN2D	1.76e-03	151	68	4	GO:0015085
GeneOntologyCellularComponent	NMDA selective glutamate receptor complex	GRIN2C GRIN2D	3.59e-04	9	67	2	GO:0017146
GeneOntologyCellularComponent	ionotropic glutamate receptor complex	GRIN2C GRIN2D SHISA7	4.06e-04	45	67	3	GO:0008328
GeneOntologyCellularComponent	neurotransmitter receptor complex	GRIN2C GRIN2D SHISA7	5.54e-04	50	67	3	GO:0098878
Domain	Sulfatase_CS	GALNS ARSD ARSF SGSH	2.36e-07	16	65	4	IPR024607
Domain	SULFATASE_1	GALNS ARSD ARSF SGSH	3.07e-07	17	65	4	PS00523
Domain	SULFATASE_2	GALNS ARSD ARSF SGSH	3.07e-07	17	65	4	PS00149
Domain	Sulfatase	GALNS ARSD ARSF SGSH	3.94e-07	18	65	4	PF00884
Domain	Sulfatase_N	GALNS ARSD ARSF SGSH	3.94e-07	18	65	4	IPR000917
Domain	Alkaline_phosphatase_core	GALNS ARSD ARSF SGSH	3.92e-06	31	65	4	IPR017850
Domain	Alkaline_Pase-like_a/b/a	GALNS ARSD ARSF SGSH	3.92e-06	31	65	4	IPR017849
Domain	-	GALNS ARSD ARSF SGSH	3.92e-06	31	65	4	3.40.720.10
Domain	ARHGEF5_35	ARHGEF35 ARHGEF5	1.19e-05	2	65	2	PF15441
Domain	ARHGEF5/35_N	ARHGEF35 ARHGEF5	1.19e-05	2	65	2	IPR029212
Domain	Peptidase_S10	SCPEP1 CPVL	3.57e-05	3	65	2	IPR001563
Domain	CARBOXYPEPT_SER_HIS	SCPEP1 CPVL	3.57e-05	3	65	2	PS00560
Domain	Peptidase_S10	SCPEP1 CPVL	3.57e-05	3	65	2	PF00450
Domain	Ser_caboxypep_ser_AS	SCPEP1 CPVL	3.57e-05	3	65	2	IPR018202
Domain	CARBOXYPEPT_SER_SER	SCPEP1 CPVL	3.57e-05	3	65	2	PS00131
Domain	Iontro_rcpt	GRIN2C GRIN2D	1.76e-03	18	65	2	IPR001320
Domain	Lig_chan-Glu_bd	GRIN2C GRIN2D	1.76e-03	18	65	2	PF10613
Domain	Iono_rcpt_met	GRIN2C GRIN2D	1.76e-03	18	65	2	IPR001508
Domain	Glu/Gly-bd	GRIN2C GRIN2D	1.76e-03	18	65	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIN2C GRIN2D	1.76e-03	18	65	2	SM00918
Domain	Lig_chan	GRIN2C GRIN2D	1.76e-03	18	65	2	PF00060
Domain	PBPe	GRIN2C GRIN2D	1.76e-03	18	65	2	SM00079
Domain	-	FCSK TOP2A	2.40e-03	21	65	2	3.30.230.10
Domain	Ribosomal_S5_D2-typ_fold_subgr	FCSK TOP2A	2.63e-03	22	65	2	IPR014721
Domain	G_patch	GPATCH2 GPANK1	2.88e-03	23	65	2	SM00443
Domain	G_patch_dom	GPATCH2 GPANK1	2.88e-03	23	65	2	IPR000467
Domain	G_PATCH	GPATCH2 GPANK1	2.88e-03	23	65	2	PS50174
Domain	G-patch	GPATCH2 GPANK1	2.88e-03	23	65	2	PF01585
Domain	Homeobox_metazoa	DLX2 HMX1 TLX2	3.81e-03	90	65	3	IPR020479
Domain	Ribosomal_S5_D2-typ_fold	FCSK TOP2A	6.23e-03	34	65	2	IPR020568
Domain	ANF_lig-bd_rcpt	GRIN2C GRIN2D	7.34e-03	37	65	2	IPR001828
Domain	ANF_receptor	GRIN2C GRIN2D	7.34e-03	37	65	2	PF01094
Domain	Peripla_BP_I	GRIN2C GRIN2D	8.13e-03	39	65	2	IPR028082
Pathway	REACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS	GRIN2C GRIN2D	1.22e-04	5	50	2	MM15655
Pathway	KEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM	GRIN2C GRIN2D	1.22e-04	5	50	2	M47667
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM	GRIN2C GRIN2D	1.83e-04	6	50	2	M47668
Pubmed	In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.	GRIN2C GRIN2D	4.11e-06	2	71	2	29651654
Pubmed	Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.	GRIN2C GRIN2D	4.11e-06	2	71	2	31110197
Pubmed	Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.	GRIN2C GRIN2D	4.11e-06	2	71	2	29317596
Pubmed	Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.	GRIN2C GRIN2D	4.11e-06	2	71	2	35057644
Pubmed	NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.	GRIN2C GRIN2D	4.11e-06	2	71	2	33766086
Pubmed	ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion.	CD3E ITPRIPL1	4.11e-06	2	71	2	38614099
Pubmed	NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.	GRIN2C GRIN2D	4.11e-06	2	71	2	31786200
Pubmed	Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.	GRIN2C GRIN2D	1.23e-05	3	71	2	9718984
Pubmed	Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.	GRIN2C GRIN2D	1.23e-05	3	71	2	35867797
Pubmed	Identification by shotgun sequencing, genomic organization, and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region.	ARSD ARSF	1.23e-05	3	71	2	9192838
Pubmed	Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components.	ATG4B TOP2A	1.23e-05	3	71	2	36633090
Pubmed	Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.	GRIN2C GRIN2D	1.23e-05	3	71	2	33421565
Pubmed	Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.	GRIN2C GRIN2D	1.23e-05	3	71	2	9480759
Pubmed	A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy.	ARSD ARSF	1.23e-05	3	71	2	7720070
Pubmed	Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death.	PLA2G3 GRIN2C GRIN2D	2.05e-05	26	71	3	9745929
Pubmed	Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.	GRIN2C GRIN2D	2.46e-05	4	71	2	8699248
Pubmed	Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.	GRIN2C GRIN2D	2.46e-05	4	71	2	9768843
Pubmed	Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.	GRIN2C GRIN2D	2.46e-05	4	71	2	36309015
Pubmed	Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.	GRIN2C GRIN2D	4.09e-05	5	71	2	26875626
Pubmed	Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.	GRIN2C GRIN2D	4.09e-05	5	71	2	26919761
Pubmed	Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem.	GRIN2C GRIN2D	4.09e-05	5	71	2	7518475
Pubmed	Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum.	GRIN2C GRIN2D	4.09e-05	5	71	2	7518474
Pubmed	Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunit.	GRIN2C GRIN2D	4.09e-05	5	71	2	9147327
Pubmed	Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina.	GRIN2C GRIN2D	4.09e-05	5	71	2	7510577
Pubmed	Neurotransmission and bipolar disorder: a systematic family-based association study.	GRIN2C GRIN2D	4.09e-05	5	71	2	18444252
Pubmed	Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland.	GRIN2C GRIN2D	4.09e-05	5	71	2	8015722
Pubmed	Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.	GRIN2C GRIN2D	4.09e-05	5	71	2	15003177
Pubmed	GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.	GRIN2C GRIN2D	4.09e-05	5	71	2	7723623
Pubmed	Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.	GRIN2C GRIN2D	4.09e-05	5	71	2	8756432
Pubmed	Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.	GRIN2C GRIN2D	4.09e-05	5	71	2	12082569
Pubmed	Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain.	GRIN2C GRIN2D	4.09e-05	5	71	2	21945132
Pubmed	Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.	GRIN2C GRIN2D	4.09e-05	5	71	2	18233995
Pubmed	Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.	GRIN2C GRIN2D	4.09e-05	5	71	2	11488959
Pubmed	Developmental changes in distribution of NMDA receptor channel subunit mRNAs.	GRIN2C GRIN2D	4.09e-05	5	71	2	1493227
Pubmed	N-methyl-D-aspartic acid receptor structure and function.	GRIN2C GRIN2D	4.09e-05	5	71	2	8036251
Pubmed	NMDA receptor activation by HIV-Tat protein is clade dependent.	GRIN2C GRIN2D	4.09e-05	5	71	2	19020013
Pubmed	Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord.	GRIN2C GRIN2D	4.09e-05	5	71	2	7929904
Pubmed	Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine.	GRIN2C GRIN2D	6.13e-05	6	71	2	25760043
Pubmed	A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity.	GRIN2C GRIN2D	6.13e-05	6	71	2	23665428
Pubmed	Altered gene expression of the N-methyl-D-aspartate receptor channel subunits in Purkinje cells of the staggerer mutant mouse.	GRIN2C GRIN2D	6.13e-05	6	71	2	8996814
Pubmed	Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.	GRIN2C GRIN2D	6.13e-05	6	71	2	9458051
Pubmed	NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit.	GRIN2C GRIN2D	6.13e-05	6	71	2	15317856
Pubmed	Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus.	GRIN2C GRIN2D	8.57e-05	7	71	2	12103442
Pubmed	Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.	GRIN2C GRIN2D	8.57e-05	7	71	2	23267846
Pubmed	Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.	GRIN2C GRIN2D	8.57e-05	7	71	2	19036954
Pubmed	Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.	GRIN2C GRIN2D	8.57e-05	7	71	2	22833210
Pubmed	HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.	GRIN2C GRIN2D	8.57e-05	7	71	2	22940423
Pubmed	Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.	GRIN2C GRIN2D	1.14e-04	8	71	2	8804048
Pubmed	HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.	GRIN2C GRIN2D	1.14e-04	8	71	2	17360663
Pubmed	Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.	GRIN2C GRIN2D	1.14e-04	8	71	2	8724036
Pubmed	The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.	GRIN2C GRIN2D	1.14e-04	8	71	2	8845955
Pubmed	Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.	GRIN2C GRIN2D	1.14e-04	8	71	2	8822372
Pubmed	Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production.	GRIN2C GRIN2D	1.14e-04	8	71	2	21106831
Pubmed	HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.	GRIN2C GRIN2D	1.14e-04	8	71	2	8563977
Pubmed	HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.	GRIN2C GRIN2D	1.14e-04	8	71	2	8821747
Pubmed	Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.	GRIN2C GRIN2D	1.14e-04	8	71	2	10448428
Pubmed	Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.	GRIN2C GRIN2D	1.14e-04	8	71	2	7695237
Pubmed	Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.	GRIN2C GRIN2D	1.14e-04	8	71	2	8955056
Pubmed	Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.	GRIN2C GRIN2D	1.14e-04	8	71	2	10555109
Pubmed	Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems.	GRIN2C GRIN2D	1.47e-04	9	71	2	17526495
Pubmed	D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.	GRIN2C GRIN2D	1.47e-04	9	71	2	22552781
Pubmed	Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.	GRIN2C GRIN2D	1.47e-04	9	71	2	21670103
Pubmed	Developmentally controlled and tissue-specific expression of unrearranged VH gene segments.	IGHV1-69 IGHV1-69D	1.47e-04	9	71	2	2578321
Pubmed	Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.	GRIN2C GRIN2D	1.47e-04	9	71	2	21491143
Pubmed	Germline diversity of the expressed BALB/c VhJ558 gene family.	IGHV1-69 IGHV1-69D	1.47e-04	9	71	2	11483206
Pubmed	Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2.	GALNS SGSH	1.47e-04	9	71	2	15962010
Pubmed	Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity.	GRIN2C GRIN2D	1.47e-04	9	71	2	16554481
Pubmed	Diversity of germ-line immunoglobulin VH genes.	IGHV1-69 IGHV1-69D	1.47e-04	9	71	2	6789211
Pubmed	PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.	GRIN2C GRIN2D	1.47e-04	9	71	2	9892651
Pubmed	N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.	GRIN2C GRIN2D	1.83e-04	10	71	2	19332541
Pubmed	Combinatorial association of V genes: one VH gene codes for three non-cross-reactive monoclonal antibodies each specific for a different antigen (phoxazolone, NP or gat).	IGHV1-69 IGHV1-69D	1.83e-04	10	71	2	3211160
Pubmed	Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase.	GRIN2C GRIN2D	2.23e-04	11	71	2	8581564
Pubmed	USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO.	ZC3H12A CHUK	2.23e-04	11	71	2	24270572
Pubmed	HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.	GRIN2C GRIN2D	2.23e-04	11	71	2	24739951
Pubmed	CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.	GRIN2C GRIN2D	2.23e-04	11	71	2	9647694
Pubmed	Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells.	GRIN2C GRIN2D	2.23e-04	11	71	2	16481105
Pubmed	Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.	GRIN2C GRIN2D	2.68e-04	12	71	2	12815021
Pubmed	Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102.	GRIN2C GRIN2D	2.68e-04	12	71	2	11937501
Pubmed	Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.	GRIN2C GRIN2D	2.68e-04	12	71	2	8665664
Pubmed	Expression patterns of sulfatase genes in the developing mouse embryo.	GALNS SGSH	3.16e-04	13	71	2	20503373
Pubmed	Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.	GRIN2C GRIN2D	3.68e-04	14	71	2	15749123
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NR2F6 MEGF8 FNTB ANKRD9 DLX2 GRIN2D CPVL WDR24 AHNAK2	4.06e-04	1105	71	9	35748872
Pubmed	Single-cell transcriptomic analysis of mouse neocortical development.	PLA2G3 MPEG1 DLX2 TOP2A	4.15e-04	170	71	4	30635555
Pubmed	Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transport.	GRIN2C GRIN2D	4.24e-04	15	71	2	21948112
Pubmed	Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.	GRIN2C GRIN2D	4.24e-04	15	71	2	10479680
Pubmed	Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure.	GRIN2C GRIN2D	5.48e-04	17	71	2	24086760
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	QRFP SOHLH1 ITPRIPL1 TOP2A AHNAK2	5.98e-04	332	71	5	37433992
Pubmed	Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.	IGHV1-69 IGHV1-69D	6.16e-04	18	71	2	6788376
Pubmed	Gene structure and chromosomal localization of the mouse NMDA receptor channel subunits.	GRIN2C GRIN2D	6.16e-04	18	71	2	9011744
Pubmed	Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis.	CD3E CHUK	6.87e-04	19	71	2	28017833
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FCSK PLEKHG2 LAS1L	7.14e-04	85	71	3	15449545
Pubmed	Bcl11b is required for differentiation and survival of alphabeta T lymphocytes.	CD3E CHUK	7.62e-04	20	71	2	12717433
Pubmed	The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.	GRIN2C GRIN2D	8.41e-04	21	71	2	22114277
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	UQCC3 FUBP1 PEX5 ARMC10 TTC17 LAS1L CPVL TOP2A AHNAK2 RAVER1	8.90e-04	1496	71	10	32877691
Pubmed	Glutamate can act as a signaling molecule in mouse preimplantation embryos†.	GRIN2C GRIN2D	1.10e-03	24	71	2	35746896
Pubmed	A dual role for Ikk alpha in tooth development.	DLX2 CHUK	1.29e-03	26	71	2	14960276
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	FUBP1 CIZ1 ARMC10 LAS1L TOP2A	1.37e-03	400	71	5	35013556
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	DLX2 SOX8	1.61e-03	29	71	2	31491374
Pubmed	Cerebellar development transcriptome database (CDT-DB): profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum.	GRIN2C GRIN2D	1.72e-03	30	71	2	18603407
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	DLX2 SOX8 HMX1 TLX2	1.76e-03	251	71	4	29031500
Cytoband	Xp22.3	ARSD ARSF CRLF2	6.40e-06	23	72	3	Xp22.3
GeneFamily	Sulfatases	GALNS ARSD ARSF SGSH	1.54e-07	18	50	4	410
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN2C GRIN2D	1.56e-04	7	50	2	1201
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF35 ARHGEF5 PLEKHG2	8.06e-04	66	50	3	722
GeneFamily	NKL subclass homeoboxes and pseudogenes	DLX2 HMX1 TLX2	8.42e-04	67	50	3	519
GeneFamily	Carboxypeptidases	SCPEP1 CPVL	1.52e-03	21	50	2	1321
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	GPATCH2 GPANK1	1.67e-03	22	50	2	579
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP31 CD2AP MPEG1 SCPEP1 ITPRIPL1 TOP2A	5.05e-07	182	72	6	bc8d621be57f76d718d9b0f11e023b0f4dcb668d

Protein segments in the cluster

Peptide	Gene	Start	Entry
MGSGLFGQRWARGPD	AMER3	701	Q8N944
GMGGWEGGIRVPGIV	ARSF	371	P54793
KGMGGWEGGIRVPGI	ARSD	381	P51689
TGLEGWGGTQEDRMG	CATSPER4	16	Q7RTX7
QDGTAGAPGLLWMGL	SMPD1	21	P17405
MGLTGEPEGLNDGEW	ARHGEF5	291	Q12774
MGLTGEPEGLNDGEW	ARHGEF35	291	A5YM69
GQEEPPLMGNGWAGG	CALHM1	316	Q8IU99
GWLEGELNGRRGMFP	CD2AP	36	Q9Y5K6
GTEMMDNRIWGPGGL	CEMIP	846	Q8WUJ3
WDFGVPQRMAGGGGP	DLX2	241	Q07687
MGGPRGAGWVAAGLL	ARMC10	1	Q8N2F6
MGVGEGKSIGQWYGP	ATG4B	131	Q9Y4P1
WGQSGAGEGRGGHMV	C17orf113	626	A0A1B0GUU1
GGQDGMLSIWDVRQG	NUP43	236	Q8NFH3
VRAGGGDMQGWEAPA	RAVER1	536	Q8IY67
MAMVTGGWGGPGGDT	NR2F6	1	P10588
LDGRWVLYGLMGGGD	TP53I3	231	Q53FA7
LPGGGWDNLRNVDMG	MPEG1	46	Q2M385
MVGGGWKRRPGAGAG	nan	1	A8MVJ9
KLLLRGGWEPGMGLG	GPANK1	261	O95872
PGGRGRGRGQGNWNM	FUBP1	356	Q96AE4
GQGLEWMGGIIPIFG	IGHV1-69	61	P01742
GQGLEWMGIINPSGG	IGHV1-46	61	P01743
AGGPWEMRERLGTGG	CHUK	11	O15111
PEGGEGVMQSWRIEG	DSG4	671	Q86SJ6
LWLQGGPGGSSMFGL	CPVL	106	Q9H3G5
GPRGEGGAMSENIWS	PEX5	591	P50542
GEEMGRAEGAWPRGP	HMX1	141	Q9NP08
VDGPDATLWMFGGLG	MEGF8	1516	Q7Z7M0
WGGQDGGGRCMEGGL	MEGF8	2141	Q7Z7M0
GAWDPEGEGMRGGSR	LMLN2	76	A0A1B0GTW7
GAGPGLGSQGMDLVW	LAS1L	6	Q9Y4W2
GGWMALGQGGAAEGV	CRLF2	16	Q9HC73
GQGLEWMGGIIPIFG	IGHV1-69D	61	A0A0B4J2H0
EPTDAMGGLGAGERW	QRFP	26	P83859
FQADGQEGPLGWMLG	ITPRIPL1	96	Q6GPH6
GGGWQDQVGGLMPGI	FCSK	881	Q8N0W3
MGWGDLGVYGEPSRE	GALNS	41	P34059
GQMVPGDTRGLWGPQ	LINC00482	96	Q8N8I6
GGEGGPGDVQAWMEA	BSND	146	Q8WZ55
GQPLGGRGQWVGEET	LINC01599	246	Q8WXQ3
MPWDARRPGGGADGG	ANKRD9	1	Q96BM1
SVGVWGQDGNEEMGG	CD3E	16	P07766
GPQQEGAMVIVSGWG	MASP1	576	P48740
RCQNWEGGIGGVPGM	FNTB	231	P49356
QNMGWTPGSGLGRDG	GPATCH2	476	Q9NW75
MGPELGWGHPRGGDV	MEIS3P1	1	A6NDR6
MSGEALGWLGQAGPL	SOHLH1	256	Q5JUK2
ALMRQRGTGGGPWGE	FAM83E	406	Q2M2I3
SELPLVMWLQGGPGG	SCPEP1	66	Q9HB40
DPTGTGMGGESIWGG	PPWD1	546	Q96BP3
GTGGGYRMEAWGGPE	SHISA7	356	A6NL88
GGIWGFIKGVAGNPM	PRRC1	211	Q96M27
WSLVPMPVRGGGGGA	SOX8	81	P57073
GAGPVWMDDVGCGGG	SSC5D	256	A1L4H1
MAEPVGKRGRWSGGS	NFATC2IP	1	Q8NCF5
GGGHQREKRGWTMPG	PLA2G3	141	Q9NZ20
KFGNGESGMGRIPDW	SGSH	196	P51688
GLKGEEVEGAGWMPG	AHNAK2	526	Q8IVF2
REMPGVWGAGGSLKV	CIZ1	536	Q9ULV3
WRKNWMVGGEGGAGG	UQCC3	76	Q6UW78
WERGGAGGMQQGSSP	ZNF414	56	Q96IQ9
QMSELWGVRGGGPGE	ZC3H12A	446	Q5D1E8
MTGGAPWGFRLQGGK	SYNPO2	11	Q9UMS6
GGLEGMQGAWGYVQG	PYROXD2	271	Q8N2H3
GEWGQEGMPPGAEGG	ARHGAP31	396	Q2M1Z3
WPLEGFGGALEMKGR	TTC17	786	Q96AE7
PMVLINGAEGIGTGW	TOP2A	846	P11388
GKHWAEGPGTGGREM	PLEKHG2	251	Q9H7P9
ETEPGGGGMRWFVDT	WDR24	401	Q96S15
GGGEGNVSQVGRVWP	TESK2	26	Q96S53
GGLAGLTFPWMDSGR	TLX2	111	O43763
GAWAGLGPGQGEQGM	GRIN2C	16	Q14957
VWFMVGPQLAGGGGS	GRIN2D	271	O15399