Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC17A2 ABCC3 ATP6V0E1 SLC17A3 SLC6A16 TMEM94 CYB561D2 ABCA9 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC44A1 SLC44A5 ABCA5 SLC25A15 ATP6V0E2 SLC6A20 SLC47A1 SLC5A12 SLC26A11 MFSD1 XPR1	5.39e-17	477	107	24	GO:0022804
GeneOntologyMolecularFunction	transporter activity	SLC17A2 ABCC3 SCN11A ATP6V0E1 SLC17A3 SLC6A16 TMEM94 PIEZO1 TRPM2 CYB561D2 OTOP2 ABCA9 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC44A1 SLC44A5 ABCA5 KCNH1 SLC25A15 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 ATG9A SLC5A12 SLC26A11 MFSD1 LMBRD1 XPR1	9.55e-14	1289	107	32	GO:0005215
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC17A2 SLC17A3 SLC6A16 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC44A1 SLC44A5 SLC25A15 SLC6A20 SLC47A1 SLC5A12 SLC26A11 MFSD1 XPR1	3.56e-13	296	107	17	GO:0015291
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC17A2 ABCC3 SCN11A ATP6V0E1 SLC17A3 SLC6A16 TMEM94 PIEZO1 TRPM2 CYB561D2 OTOP2 ABCA9 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC44A1 SLC44A5 ABCA5 KCNH1 SLC25A15 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 SLC5A12 SLC26A11 MFSD1 XPR1	3.79e-13	1180	107	30	GO:0022857
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR51T1 NPBWR1 ADGRG3 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 TAAR3P GPR52 EDNRB CCKBR OR1D2 GNRHR2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 SMO OR52A1 GPR148 HRH3 CXCR1 CXCR2	7.54e-13	884	107	26	GO:0004930
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC17A2 ABCC3 SCN11A ATP6V0E1 SLC17A3 TMEM94 TRPM2 OTOP2 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 SLC5A12 SLC26A11 XPR1	5.08e-10	758	107	21	GO:0015318
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC17A2 ATP6V0E1 SLC17A3 TMEM94 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 ATP6V0E2 SLC6A20 SLC47A1 SLC5A12 SLC26A11	8.01e-10	301	107	14	GO:0022853
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC17A2 SCN11A ATP6V0E1 SLC17A3 TMEM94 PIEZO1 TRPM2 OTOP2 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 SLC5A12	2.24e-09	664	107	19	GO:0008324
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC17A2 SCN11A ATP6V0E1 SLC17A3 TMEM94 TRPM2 OTOP2 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 SLC5A12	5.94e-09	627	107	18	GO:0022890
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC17A2 SCN11A ATP6V0E1 SLC17A3 TMEM94 PIEZO1 TRPM2 OTOP2 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 SLC5A12 SLC26A11	6.90e-09	793	107	20	GO:0015075
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR51T1 NPBWR1 ADGRG3 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 TAAR3P GPR52 EDNRB CCKBR OR1D2 GNRHR2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 SMO OR52A1 GPR148 HRH3 CXCR1 CXCR2	8.00e-09	1353	107	26	GO:0004888
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC47A2 SLC6A6 SLC6A8 SLC44A1 SLC44A5 SLC25A15 SLC6A20 SLC47A1	1.47e-08	83	107	8	GO:0015101
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC17A2 SCN11A SLC17A3 TRPM2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC6A20 SLC5A12	2.80e-08	171	107	10	GO:0015081
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC17A2 SLC17A3 SLC6A6 SLC6A8 SLC6A13 SLC6A20 SLC5A12	2.61e-07	81	107	7	GO:0015370
GeneOntologyMolecularFunction	monocarboxylate:sodium symporter activity	SLC6A6 SLC6A8 SLC6A13 SLC5A12	1.02e-06	15	107	4	GO:0140161
GeneOntologyMolecularFunction	organic acid:sodium symporter activity	SLC6A6 SLC6A8 SLC6A13 SLC6A20 SLC5A12	1.15e-06	35	107	5	GO:0005343
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC17A2 SCN11A SLC17A3 TMEM94 TRPM2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 SLC6A20 TRPV2 SLC5A12	1.24e-06	465	107	13	GO:0046873
GeneOntologyMolecularFunction	symporter activity	SLC17A2 SLC17A3 SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20 SLC5A12	1.46e-06	150	107	8	GO:0015293
GeneOntologyMolecularFunction	secondary active monocarboxylate transmembrane transporter activity	SLC6A6 SLC6A8 SLC6A13 SLC5A12	2.84e-06	19	107	4	GO:0015355
GeneOntologyMolecularFunction	gamma-aminobutyric acid:sodium:chloride symporter activity	SLC6A6 SLC6A8 SLC6A13	2.96e-06	6	107	3	GO:0005332
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC17A2 SLC17A3 SLC6A6 SLC6A8 SLC6A13 SLC6A20 SLC5A12	3.56e-06	119	107	7	GO:0015294
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC17A2 ABCC3 SLC17A3 SLC6A6 SLC6A8 SLC6A13 SLC26A11 XPR1	3.89e-06	171	107	8	GO:0015103
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC3 SLC17A3 SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 SLC5A12 SLC26A11	3.98e-06	293	107	10	GO:0008514
GeneOntologyMolecularFunction	amino acid:sodium symporter activity	SLC6A6 SLC6A8 SLC6A13 SLC6A20	6.38e-06	23	107	4	GO:0005283
GeneOntologyMolecularFunction	choline transmembrane transporter activity	SLC6A8 SLC44A1 SLC44A5	8.22e-06	8	107	3	GO:0015220
GeneOntologyMolecularFunction	antiporter activity	SLC47A2 SLC9A4 SLC44A1 SLC44A5 SLC25A15 SLC47A1 SLC26A11	9.48e-06	138	107	7	GO:0015297
GeneOntologyMolecularFunction	gamma-aminobutyric acid transmembrane transporter activity	SLC6A6 SLC6A8 SLC6A13	1.23e-05	9	107	3	GO:0015185
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	ABCC3 SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 SLC5A12	1.58e-05	207	107	8	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	ABCC3 SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 SLC5A12	1.63e-05	208	107	8	GO:0005342
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC6A6 SLC6A8 SLC6A13 SLC6A20	1.67e-05	29	107	4	GO:0005416
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	ABCC3 SLC6A6 SLC6A13 SLC47A1 SLC26A11	1.88e-05	61	107	5	GO:1901682
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1	2.15e-05	105	107	6	GO:0015171
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC3 ATP6V0E1 TMEM94 ABCA9 ABCA5 ATP6V0E2	2.66e-05	109	107	6	GO:0042626
GeneOntologyMolecularFunction	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	ALG10B ALG10	2.84e-05	2	107	2	GO:0106073
GeneOntologyMolecularFunction	polyspecific organic cation:proton antiporter activity	SLC47A2 SLC47A1	2.84e-05	2	107	2	GO:0140968
GeneOntologyMolecularFunction	interleukin-8 receptor activity	CXCR1 CXCR2	2.84e-05	2	107	2	GO:0004918
GeneOntologyMolecularFunction	alkenylglycerophosphocholine hydrolase activity	TMEM86B TMEM86A	2.84e-05	2	107	2	GO:0047408
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC3 SLC17A3 SLC47A2 SLC47A1	3.19e-05	34	107	4	GO:0042910
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCC3 ATP6V0E1 TMEM94 CYB561D2 ABCA9 ABCA5 ATP6V0E2	4.90e-05	178	107	7	GO:0015399
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	NPBWR1 MCHR2 NPSR1 EDNRB CCKBR GPR83	8.13e-05	133	107	6	GO:0008528
GeneOntologyMolecularFunction	interleukin-8 binding	CXCR1 CXCR2	8.50e-05	3	107	2	GO:0019959
GeneOntologyMolecularFunction	taurine:sodium symporter activity	SLC6A6 SLC6A13	8.50e-05	3	107	2	GO:0005369
GeneOntologyMolecularFunction	sodium:chloride symporter activity	SLC6A6 SLC6A8 SLC6A13	9.63e-05	17	107	3	GO:0015378
GeneOntologyMolecularFunction	peptide receptor activity	NPBWR1 MCHR2 NPSR1 EDNRB CCKBR GPR83	1.08e-04	140	107	6	GO:0001653
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	ABCC3 SLC6A6 SLC6A8 SLC6A13 SLC5A12	1.23e-04	90	107	5	GO:0008028
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A6 SLC6A8 SLC6A13	1.36e-04	19	107	3	GO:0015373
GeneOntologyMolecularFunction	creatine transmembrane transporter activity	SLC6A8 SLC6A13	1.69e-04	4	107	2	GO:0005308
GeneOntologyMolecularFunction	chloride:monoatomic cation symporter activity	SLC6A6 SLC6A8 SLC6A13	2.45e-04	23	107	3	GO:0015377
GeneOntologyMolecularFunction	phosphate transmembrane transporter activity	SLC17A2 SLC17A3 XPR1	2.79e-04	24	107	3	GO:0005315
GeneOntologyMolecularFunction	taurine transmembrane transporter activity	SLC6A6 SLC6A13	2.81e-04	5	107	2	GO:0005368
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A6 SLC6A8 SLC6A13	3.56e-04	26	107	3	GO:0015296
GeneOntologyMolecularFunction	proton transmembrane transporter activity	ATP6V0E1 OTOP2 SLC47A2 SLC9A4 ATP6V0E2 SLC47A1	5.29e-04	188	107	6	GO:0015078
GeneOntologyMolecularFunction	C-X-C chemokine binding	CXCR1 CXCR2	5.87e-04	7	107	2	GO:0019958
GeneOntologyMolecularFunction	modified amino acid transmembrane transporter activity	SLC6A8 SLC6A13 SLC6A20	7.26e-04	33	107	3	GO:0072349
GeneOntologyMolecularFunction	C-X-C chemokine receptor activity	CXCR1 CXCR2	7.80e-04	8	107	2	GO:0016494
GeneOntologyMolecularFunction	glycosyltransferase activity	MGAT4B DPY19L3 ST8SIA1 ALG10B ALG10 PIGM LARGE1	9.21e-04	288	107	7	GO:0016757
GeneOntologyMolecularFunction	hexosyltransferase activity	MGAT4B DPY19L3 ALG10B ALG10 PIGM LARGE1	9.66e-04	211	107	6	GO:0016758
GeneOntologyMolecularFunction	urate transmembrane transporter activity	SLC17A2 SLC17A3	9.99e-04	9	107	2	GO:0015143
GeneOntologyMolecularFunction	salt transmembrane transporter activity	SLC17A2 SLC17A3	9.99e-04	9	107	2	GO:1901702
GeneOntologyMolecularFunction	angiotensin receptor binding	DRD1 EDNRB	1.24e-03	10	107	2	GO:0031701
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC17A3 SLC6A6 SLC6A8 SLC6A13 SLC26A11	1.32e-03	151	107	5	GO:0008509
GeneOntologyMolecularFunction	sodium:phosphate symporter activity	SLC17A2 SLC17A3	1.81e-03	12	107	2	GO:0005436
GeneOntologyMolecularFunction	arrestin family protein binding	DRD1 GPR135	1.81e-03	12	107	2	GO:1990763
GeneOntologyMolecularFunction	L-arginine transmembrane transporter activity	SLC25A15 SLC47A1	2.13e-03	13	107	2	GO:0061459
GeneOntologyMolecularFunction	hydrolase activity, acting on ether bonds	TMEM86B TMEM86A	2.13e-03	13	107	2	GO:0016801
GeneOntologyMolecularFunction	ether hydrolase activity	TMEM86B TMEM86A	2.13e-03	13	107	2	GO:0016803
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCA9 ABCA5	2.30e-03	49	107	3	GO:0140359
GeneOntologyMolecularFunction	neuropeptide receptor activity	NPBWR1 NPSR1 GPR83	2.88e-03	53	107	3	GO:0008188
GeneOntologyMolecularFunction	efflux transmembrane transporter activity	SLC17A3 XPR1	3.25e-03	16	107	2	GO:0015562
GeneOntologyMolecularFunction	monoatomic ion channel activity	SCN11A SLC17A3 PIEZO1 TRPM2 OTOP2 KCNH1 TRPV2 SLC26A11	3.29e-03	459	107	8	GO:0005216
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	ATP6V0E1 TMEM94 ATP6V0E2	4.50e-03	62	107	3	GO:0019829
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A6 SLC6A8 SLC6A13 SLC26A11	4.60e-03	125	107	4	GO:0015108
GeneOntologyMolecularFunction	basic amino acid transmembrane transporter activity	SLC25A15 SLC47A1	5.07e-03	20	107	2	GO:0015174
GeneOntologyMolecularFunction	glucosyltransferase activity	ALG10B ALG10	6.13e-03	22	107	2	GO:0046527
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	ABCC3 SLC44A1 SLC5A12	6.31e-03	70	107	3	GO:1901618
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC25A15 SLC6A20 SLC47A1	6.57e-03	71	107	3	GO:0015179
GeneOntologyMolecularFunction	C-C chemokine receptor activity	CXCR1 CXCR2	6.69e-03	23	107	2	GO:0016493
GeneOntologyMolecularFunction	C-C chemokine binding	CXCR1 CXCR2	7.27e-03	24	107	2	GO:0019957
GeneOntologyMolecularFunction	ATPase-coupled ion transmembrane transporter activity	ATP6V0E1 ATP6V0E2	7.27e-03	24	107	2	GO:0042625
GeneOntologyMolecularFunction	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	ATP6V0E1 ATP6V0E2	7.27e-03	24	107	2	GO:0044769
GeneOntologyMolecularFunction	proton-transporting ATPase activity, rotational mechanism	ATP6V0E1 ATP6V0E2	7.27e-03	24	107	2	GO:0046961
GeneOntologyMolecularFunction	channel activity	SCN11A SLC17A3 PIEZO1 TRPM2 OTOP2 KCNH1 TRPV2 SLC26A11	7.28e-03	525	107	8	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	SCN11A SLC17A3 PIEZO1 TRPM2 OTOP2 KCNH1 TRPV2 SLC26A11	7.36e-03	526	107	8	GO:0022803
GeneOntologyMolecularFunction	G protein-coupled chemoattractant receptor activity	CXCR1 CXCR2	8.50e-03	26	107	2	GO:0001637
GeneOntologyMolecularFunction	chemokine receptor activity	CXCR1 CXCR2	8.50e-03	26	107	2	GO:0004950
GeneOntologyMolecularFunction	olfactory receptor activity	OR51T1 OR5V1 OR1D2 OR51E1 OR52E8 OR52A1 GPR148	8.54e-03	431	107	7	GO:0004984
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC17A2 SCN11A DRD1 ATP6V0E1 SLC17A3 SLC6A16 TMEM94 TRPM2 NPSR1 OTOP2 SLC47A2 EDNRB AMIGO1 ALG10B SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 ALG10 SLC6A20 TRPV2 SLC47A1 SLC26A11 XPR1 LARGE1	1.30e-12	1017	107	27	GO:0098660
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC17A2 SCN11A DRD1 ATP6V0E1 SLC17A3 SLC6A16 TMEM94 PIEZO1 TRPM2 NPSR1 OTOP2 SLC47A2 EDNRB AMIGO1 ALG10B SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 ALG10 SLC6A20 TRPV2 SLC47A1 LARGE1	1.54e-12	942	107	26	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC17A2 ABCC3 SCN11A DRD1 ATP6V0E1 SLC17A3 SLC6A16 TMEM94 PIEZO1 TRPM2 NPSR1 OTOP2 SLC47A2 EDNRB AMIGO1 ALG10B SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 ALG10 SLC6A20 TRPV2 SLC47A1 SLC26A11 LARGE1	1.74e-12	1115	107	28	GO:0034220
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC17A2 SCN11A DRD1 ATP6V0E1 SLC17A3 SLC6A16 TMEM94 TRPM2 NPSR1 OTOP2 SLC47A2 EDNRB AMIGO1 ALG10B SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 ALG10 SLC6A20 TRPV2 SLC47A1 LARGE1	6.62e-12	922	107	25	GO:0098662
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC17A2 ABCC3 SCN11A DRD1 ATP6V0E1 SLC17A3 SLC6A16 TMEM94 PIEZO1 TRPM2 NPSR1 OTOP2 SLC47A2 EDNRB AMIGO1 ALG10B SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 ALG10 SLC6A20 TRPV2 SLC47A1 SLC5A12 SLC26A11 HRH3 LARGE1	7.98e-12	1374	107	30	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC17A2 SCN11A DRD1 ATP6V0E1 SLC17A3 SLC6A16 TMEM94 PIEZO1 TRPM2 NPSR1 OTOP2 SLC47A2 EDNRB AMIGO1 ALG10B SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ATP6V0E2 ALG10 SLC6A20 TRPV2 SLC47A1 SLC5A12 LARGE1	2.55e-11	1157	107	27	GO:0006812
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR51T1 NPBWR1 SCN11A ADGRG3 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 TAAR3P GPR52 LMBRD2 ADCY7 EDNRB CCKBR OR1D2 GNRHR2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 SMO OR52A1 GPR148 HRH3 CXCR1 CXCR2	6.35e-11	1395	107	29	GO:0007186
GeneOntologyBiologicalProcess	sodium ion transport	SLC17A2 SCN11A SLC17A3 SLC6A16 TRPM2 EDNRB SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC6A20 SLC5A12	2.00e-08	275	107	12	GO:0006814
GeneOntologyBiologicalProcess	metal ion transport	SLC17A2 SCN11A DRD1 SLC17A3 SLC6A16 TMEM94 TRPM2 NPSR1 EDNRB AMIGO1 ALG10B SLC6A6 SLC6A8 SLC6A13 SLC9A4 KCNH1 ALG10 SLC6A20 TRPV2 SLC5A12 LARGE1	3.78e-08	1000	107	21	GO:0030001
GeneOntologyBiologicalProcess	organic cation transport	SLC47A2 SLC6A6 ADORA3 SLC44A1 SLC44A5 SLC25A15 SLC6A20 SLC47A1 HRH3	6.53e-08	145	107	9	GO:0015695
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC17A2 SCN11A SLC17A3 SLC6A16 TRPM2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC6A20	1.32e-07	208	107	10	GO:0035725
GeneOntologyBiologicalProcess	organic anion transport	SLC17A2 ABCC3 SLC17A3 SLC6A6 SLC6A8 SLC6A13 G6PC3 SLC25A15 SLC6A20 SLC47A1 SLC5A12 SLC26A11 HRH3	2.69e-06	515	107	13	GO:0015711
GeneOntologyBiologicalProcess	amino acid transport	SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 HRH3	8.10e-06	195	107	8	GO:0006865
GeneOntologyBiologicalProcess	gamma-aminobutyric acid transport	SLC6A6 SLC6A8 SLC6A13 HRH3	1.27e-05	28	107	4	GO:0015812
GeneOntologyBiologicalProcess	organic acid transmembrane transport	SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 SLC5A12	2.66e-05	167	107	7	GO:1903825
GeneOntologyBiologicalProcess	interleukin-8-mediated signaling pathway	CXCR1 CXCR2	2.67e-05	2	107	2	GO:0038112
GeneOntologyBiologicalProcess	carboxylic acid transport	ABCC3 SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 SLC5A12 SLC26A11 HRH3	5.46e-05	410	107	10	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	ABCC3 SLC6A6 SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 SLC5A12 SLC26A11 HRH3	5.68e-05	412	107	10	GO:0015849
GeneOntologyBiologicalProcess	phospholipase C-activating G protein-coupled receptor signaling pathway	DRD1 EDNRB CCKBR GPR83 GPR174 CXCR2	6.81e-05	133	107	6	GO:0007200
GeneOntologyBiologicalProcess	vascular process in circulatory system	ABCC3 DRD1 EDNRB SLC6A6 SLC6A13 SLC44A1 SLC6A20 CLDN5 CXCR2	7.68e-05	344	107	9	GO:0003018
GeneOntologyBiologicalProcess	cellular response to interleukin-8	CXCR1 CXCR2	7.97e-05	3	107	2	GO:0098759
GeneOntologyBiologicalProcess	response to interleukin-8	CXCR1 CXCR2	7.97e-05	3	107	2	GO:0098758
GeneOntologyBiologicalProcess	transport across blood-brain barrier	ABCC3 SLC6A6 SLC6A13 SLC44A1 SLC6A20	9.01e-05	87	107	5	GO:0150104
GeneOntologyBiologicalProcess	vascular transport	ABCC3 SLC6A6 SLC6A13 SLC44A1 SLC6A20	9.52e-05	88	107	5	GO:0010232
GeneOntologyBiologicalProcess	creatine transmembrane transport	SLC6A8 SLC6A13	1.59e-04	4	107	2	GO:0015881
GeneOntologyBiologicalProcess	import across plasma membrane	TRPM2 SLC6A6 SLC6A13 SLC9A4 SLC6A20 TRPV2 SLC47A1	1.98e-04	230	107	7	GO:0098739
GeneOntologyBiologicalProcess	carboxylic acid transmembrane transport	SLC6A8 SLC6A13 SLC25A15 SLC6A20 SLC47A1 SLC5A12	2.08e-04	163	107	6	GO:1905039
GeneOntologyBiologicalProcess	amino acid import across plasma membrane	SLC6A6 SLC6A13 SLC6A20 SLC47A1	2.34e-04	58	107	4	GO:0089718
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	DRD1 ADCY7 EDNRB ADORA3	2.50e-04	59	107	4	GO:0045761
GeneOntologyBiologicalProcess	proton transmembrane transport	ATP6V0E1 OTOP2 SLC47A2 SLC9A4 ATP6V0E2 SLC47A1	2.61e-04	170	107	6	GO:1902600
GeneOntologyBiologicalProcess	xenobiotic transport	ABCC3 SLC17A3 SLC47A2 SLC47A1	3.42e-04	64	107	4	GO:0042908
GeneOntologyBiologicalProcess	xenobiotic detoxification by transmembrane export across the plasma membrane	SLC17A3 SLC47A2 SLC47A1	3.63e-04	27	107	3	GO:1990961
GeneOntologyBiologicalProcess	sulfur compound transport	SLC6A6 SLC6A13 SLC47A1 SLC26A11	3.63e-04	65	107	4	GO:0072348
GeneOntologyBiologicalProcess	detection of stimulus	OR51T1 SCN11A OR5V1 PIEZO1 GPR52 OR1D2 OR51E1 NOD1 OR52E8 SMO OR52A1 GPR148	3.66e-04	722	107	12	GO:0051606
GeneOntologyBiologicalProcess	gamma-aminobutyric acid import	SLC6A6 SLC6A13	3.95e-04	6	107	2	GO:0051939
GeneOntologyBiologicalProcess	amino acid transmembrane transport	SLC6A6 SLC6A13 SLC25A15 SLC6A20 SLC47A1	4.06e-04	120	107	5	GO:0003333
GeneOntologyBiologicalProcess	regulation of pH	ATP6V0E1 EDNRB CCKBR SLC9A4 ATP6V0E2	4.06e-04	120	107	5	GO:0006885
GeneOntologyBiologicalProcess	neurotransmitter transport	DRD1 SLC6A16 SLC6A6 SLC6A8 SLC6A13 KCNH1 HRH3	4.07e-04	259	107	7	GO:0006836
GeneOntologyBiologicalProcess	circulatory system process	ABCC3 SCN11A DRD1 EDNRB SLC6A6 SLC6A13 ADORA3 SLC44A1 SLC6A20 CLDN5 HRH3 CXCR2	4.19e-04	733	107	12	GO:0003013
GeneOntologyBiologicalProcess	xenobiotic export from cell	SLC17A3 SLC47A2 SLC47A1	4.50e-04	29	107	3	GO:0046618
GeneOntologyBiologicalProcess	dendritic cell chemotaxis	TRPM2 CXCR1 CXCR2	4.50e-04	29	107	3	GO:0002407
GeneOntologyBiologicalProcess	regulation of cyclase activity	DRD1 ADCY7 EDNRB ADORA3	4.57e-04	69	107	4	GO:0031279
GeneOntologyBiologicalProcess	phasic smooth muscle contraction	SCN11A DRD1 EDNRB	4.98e-04	30	107	3	GO:0014821
GeneOntologyBiologicalProcess	multicellular organismal response to stress	SCN11A DRD1 EDNRB CCKBR LARGE1	5.08e-04	126	107	5	GO:0033555
GeneOntologyBiologicalProcess	potassium ion transport	DRD1 AMIGO1 ALG10B SLC9A4 KCNH1 ALG10 LARGE1	5.45e-04	272	107	7	GO:0006813
GeneOntologyBiologicalProcess	dentate gyrus development	DRD1 SMO LARGE1	5.49e-04	31	107	3	GO:0021542
GeneOntologyBiologicalProcess	hexose phosphate transport	SLC17A3 G6PC3	5.50e-04	7	107	2	GO:0015712
GeneOntologyBiologicalProcess	glucose-6-phosphate transport	SLC17A3 G6PC3	5.50e-04	7	107	2	GO:0015760
GeneOntologyBiologicalProcess	regulation of lyase activity	DRD1 ADCY7 EDNRB ADORA3	5.66e-04	73	107	4	GO:0051339
GeneOntologyBiologicalProcess	activation of adenylate cyclase activity	DRD1 ADCY7 ADORA3	7.23e-04	34	107	3	GO:0007190
GeneOntologyBiologicalProcess	alkanesulfonate transmembrane transport	SLC6A6 SLC6A13	7.31e-04	8	107	2	GO:0042918
GeneOntologyBiologicalProcess	choline metabolic process	BCHE SLC44A1	7.31e-04	8	107	2	GO:0019695
GeneOntologyBiologicalProcess	taurine transmembrane transport	SLC6A6 SLC6A13	7.31e-04	8	107	2	GO:0015734
GeneOntologyBiologicalProcess	dendritic cell migration	TRPM2 CXCR1 CXCR2	8.56e-04	36	107	3	GO:0036336
GeneOntologyBiologicalProcess	excretion	SCN11A NPSR1 EDNRB	9.28e-04	37	107	3	GO:0007588
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	DRD1 ADCY7 ADORA3	1.17e-03	40	107	3	GO:0045762
GeneOntologyBiologicalProcess	choline transport	SLC44A1 SLC44A5	1.17e-03	10	107	2	GO:0015871
GeneOntologyBiologicalProcess	sensory perception	OR51T1 SCN11A OR5V1 TAAR3P ALG10B OR1D2 OR51E1 ELFN1 ALG10 OR52E8 TRPV2 OR52A1 GPR148 LARGE1	1.29e-03	1072	107	14	GO:0007600
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	AMIGO1 ALG10B SLC9A4 KCNH1 ALG10 LARGE1	1.33e-03	232	107	6	GO:0071805
GeneOntologyBiologicalProcess	urate transport	SLC17A2 SLC17A3	1.42e-03	11	107	2	GO:0015747
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	DRD1 DPY19L3 SLC17A3 TMEM94 PIEZO1 CYB561D2 CH25H PTDSS1 TMEM86B SCD5 ALG10B LMF2 G6PC3 CLMN CERS3 ALG10 ATG9A TMEM86A LMBRD1 PIGM	1.34e-05	1327	108	20	GO:0042175
GeneOntologyCellularComponent	endoplasmic reticulum membrane	DRD1 DPY19L3 SLC17A3 TMEM94 PIEZO1 CYB561D2 CH25H PTDSS1 TMEM86B SCD5 ALG10B LMF2 G6PC3 CERS3 ALG10 ATG9A TMEM86A LMBRD1 PIGM	3.22e-05	1293	108	19	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	DRD1 DPY19L3 SLC17A3 TMEM94 PIEZO1 CYB561D2 CH25H PTDSS1 TMEM86B SCD5 ALG10B LMF2 G6PC3 CERS3 ALG10 ATG9A TMEM86A LMBRD1 PIGM	3.43e-05	1299	108	19	GO:0098827
GeneOntologyCellularComponent	apical plasma membrane	SLC17A2 SLC17A3 SLC47A2 SLC6A6 SLC6A8 SLC9A4 NOD1 SLC6A20 SLC47A1 SLC5A12 SLC26A11	4.43e-05	487	108	11	GO:0016324
GeneOntologyCellularComponent	apical part of cell	SLC17A2 SLC17A3 SLC47A2 SLC6A6 SLC6A8 SLC9A4 NOD1 SLC6A20 SLC47A1 SLC5A12 SLC26A11	2.47e-04	592	108	11	GO:0045177
GeneOntologyCellularComponent	vacuolar membrane	GPR137 ATP6V0E1 TRPM2 ABCA5 GPR137C ATP6V0E2 ATG9A SLC26A11 MFSD1 LMBRD1	2.98e-04	507	108	10	GO:0005774
GeneOntologyCellularComponent	lysosomal membrane	GPR137 ATP6V0E1 TRPM2 ABCA5 GPR137C ATP6V0E2 SLC26A11 MFSD1 LMBRD1	6.59e-04	462	108	9	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	GPR137 ATP6V0E1 TRPM2 ABCA5 GPR137C ATP6V0E2 SLC26A11 MFSD1 LMBRD1	6.59e-04	462	108	9	GO:0098852
GeneOntologyCellularComponent	basolateral plasma membrane	ABCC3 SLC6A6 SLC6A13 SLC9A4 NOD1 SLC47A1 SLC26A11	1.37e-03	320	108	7	GO:0016323
GeneOntologyCellularComponent	secretory granule membrane	ADGRG3 TRPM2 DCST1 SLC9A4 MCEMP1 CXCR1 CXCR2	1.61e-03	329	108	7	GO:0030667
GeneOntologyCellularComponent	axonal growth cone	SCN11A TRPV2 SMO	1.63e-03	45	108	3	GO:0044295
GeneOntologyCellularComponent	proton-transporting V-type ATPase, V0 domain	ATP6V0E1 ATP6V0E2	1.69e-03	12	108	2	GO:0033179
GeneOntologyCellularComponent	basal plasma membrane	ABCC3 SLC6A6 SLC6A13 SLC9A4 NOD1 SLC47A1 SLC26A11	2.43e-03	354	108	7	GO:0009925
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	ADGRG3 ATP6V0E1 TRPM2 CYB561D2 GPR135 DCST1 SLC9A4 ABCA5 KCNH1 ATP6V0E2 SMO ATG9A MCEMP1 CXCR1 CXCR2	2.93e-03	1307	108	15	GO:0030659
GeneOntologyCellularComponent	synaptic membrane	SCN11A DRD1 SLC6A6 SLC6A8 ADORA3 KCNH1 ELFN1 ATG9A PCDH8	3.25e-03	583	108	9	GO:0097060
GeneOntologyCellularComponent	vesicle membrane	ADGRG3 ATP6V0E1 TRPM2 CYB561D2 GPR135 DCST1 SLC9A4 ABCA5 KCNH1 ATP6V0E2 SMO ATG9A MCEMP1 CXCR1 CXCR2	3.33e-03	1325	108	15	GO:0012506
GeneOntologyCellularComponent	basal part of cell	ABCC3 SLC6A6 SLC6A13 SLC9A4 NOD1 SLC47A1 SLC26A11	3.50e-03	378	108	7	GO:0045178
Domain	7tm_1	OR51T1 NPBWR1 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 TAAR3P GPR52 EDNRB CCKBR OR1D2 GNRHR2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 OR52A1 GPR148 HRH3 CXCR1 CXCR2	3.36e-13	677	105	24	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR51T1 NPBWR1 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 TAAR3P GPR52 EDNRB CCKBR OR1D2 GNRHR2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 OR52A1 GPR148 HRH3 CXCR1 CXCR2	4.32e-13	685	105	24	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR51T1 NPBWR1 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 TAAR3P GPR52 EDNRB CCKBR OR1D2 GNRHR2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 OR52A1 GPR148 HRH3 CXCR1 CXCR2	5.21e-13	691	105	24	PS50262
Domain	GPCR_Rhodpsn	OR51T1 NPBWR1 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 TAAR3P GPR52 EDNRB CCKBR OR1D2 GNRHR2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 OR52A1 GPR148 HRH3 CXCR1 CXCR2	5.37e-13	692	105	24	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR51T1 NPBWR1 DRD1 OR5V1 MRGPRD MCHR2 NPSR1 GPR135 GPR52 EDNRB CCKBR OR1D2 GPR83 ADORA3 OR51E1 GPR174 OR52E8 OR52A1 GPR148 HRH3 CXCR1 CXCR2	1.69e-11	670	105	22	IPR017452
Domain	NA_NEUROTRAN_SYMP_2	SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20	4.12e-08	18	105	5	PS00754
Domain	SNF	SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20	5.57e-08	19	105	5	PF00209
Domain	NA_NEUROTRAN_SYMP_1	SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20	5.57e-08	19	105	5	PS00610
Domain	NA_NEUROTRAN_SYMP_3	SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20	5.57e-08	19	105	5	PS50267
Domain	Na/ntran_symport	SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20	5.57e-08	19	105	5	IPR000175
Domain	MATE_fam	SLC47A2 SLC47A1	3.13e-05	2	105	2	IPR002528
Domain	Alg10	ALG10B ALG10	3.13e-05	2	105	2	IPR016900
Domain	ATPase_V0-cplx_e1/e2_su	ATP6V0E1 ATP6V0E2	3.13e-05	2	105	2	IPR008389
Domain	YhhN	TMEM86B TMEM86A	3.13e-05	2	105	2	IPR012506
Domain	MatE	SLC47A2 SLC47A1	3.13e-05	2	105	2	PF01554
Domain	DIE2_ALG10	ALG10B ALG10	3.13e-05	2	105	2	PF04922
Domain	ATPase_V0-cplx_e1/e2_su_met	ATP6V0E1 ATP6V0E2	3.13e-05	2	105	2	IPR017385
Domain	YhhN	TMEM86B TMEM86A	3.13e-05	2	105	2	PF07947
Domain	ATP_synt_H	ATP6V0E1 ATP6V0E2	3.13e-05	2	105	2	PF05493
Domain	Chemokine_CXCR_1/2	CXCR1 CXCR2	3.13e-05	2	105	2	IPR000174
Domain	GPR137	GPR137 GPR137C	9.36e-05	3	105	2	IPR029723
Domain	Pecanex_C	PCNX3 PCNX1	1.86e-04	4	105	2	PF05041
Domain	LMBR1	LMBRD2 LMBRD1	1.86e-04	4	105	2	PF04791
Domain	Pecanex	PCNX3 PCNX1	1.86e-04	4	105	2	IPR007735
Domain	LMBR1-like_membr_prot	LMBRD2 LMBRD1	1.86e-04	4	105	2	IPR006876
Domain	Choline_transpo	SLC44A1 SLC44A5	3.10e-04	5	105	2	PF04515
Domain	Choline_transptr-like	SLC44A1 SLC44A5	3.10e-04	5	105	2	IPR007603
Domain	CXCR4/ACKR2	CXCR1 CXCR2	6.45e-04	7	105	2	IPR001277
Domain	ABC_A	ABCA9 ABCA5	1.99e-03	12	105	2	IPR026082
Domain	ABC_tran	ABCC3 ABCA9 ABCA5	2.49e-03	48	105	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA9 ABCA5	2.49e-03	48	105	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA9 ABCA5	2.64e-03	49	105	3	PS00211
Domain	ABC_transporter-like	ABCC3 ABCA9 ABCA5	2.79e-03	50	105	3	IPR003439
Domain	MFS	SLC17A2 SLC17A3 MFSD6L MFSD1	3.23e-03	108	105	4	PS50850
Domain	7TM_GPCR_Srsx	DRD1 EDNRB GPR83 ADORA3	3.68e-03	112	105	4	SM01381
Domain	Ion_trans_dom	SCN11A TRPM2 KCNH1 TRPV2	3.92e-03	114	105	4	IPR005821
Domain	Ion_trans	SCN11A TRPM2 KCNH1 TRPV2	3.92e-03	114	105	4	PF00520
Domain	MFS_dom	SLC17A2 SLC17A3 MFSD6L MFSD1	6.93e-03	134	105	4	IPR020846
Domain	MFS_1	SLC17A2 SLC17A3 MFSD1	9.35e-03	77	105	3	PF07690
Domain	MFS	SLC17A2 SLC17A3 MFSD1	9.35e-03	77	105	3	IPR011701
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	NPBWR1 DRD1 OR5V1 GPR52 EDNRB CCKBR OR1D2 GPR83 ADORA3 GPR174 HRH3 CXCR1 CXCR2	1.61e-09	260	78	13	M39397
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC3 ATP6V0E1 SLC17A3 TRPM2 ABCA9 SLC47A2 ADCY7 SLC6A6 SLC6A13 SLC9A4 SLC44A1 LMF2 SLC44A5 ABCA5 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 SLC5A12 SLC26A11	1.98e-09	736	78	20	M27287
Pathway	WP_GPCRS_OTHER	MCHR2 GPR135 TAAR3P CCKBR GPR83 ADORA3 SMO CXCR1 CXCR2	2.00e-09	93	78	9	M39629
Pathway	WP_GPCRS_NONODORANT	NPBWR1 DRD1 MRGPRD NPSR1 EDNRB CCKBR ADORA3 GPR174 SMO HRH3 CXCR1 CXCR2	2.29e-08	266	78	12	MM15843
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC3 ATP6V0E1 SLC17A3 TRPM2 ABCA9 SLC6A6 SLC6A13 SLC9A4 SLC44A1 LMF2 SLC44A5 ABCA5 ATP6V0E2 SLC6A20 TRPV2 SLC47A1 SLC5A12 SLC26A11	2.29e-08	681	78	18	MM14985
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC47A2 SLC6A6 SLC6A13 SLC44A1 SLC44A5 SLC6A20 SLC47A1	3.89e-07	84	78	7	M27334
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC47A2 SLC6A6 SLC6A13 SLC9A4 SLC44A1 SLC44A5 SLC6A20 SLC47A1 SLC5A12 SLC26A11	1.08e-06	249	78	10	M5988
Pathway	REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS	SLC6A6 SLC6A13 SLC44A1 SLC44A5 SLC6A20 SLC47A1	3.79e-06	76	78	6	MM15072
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC6A6 SLC6A13 SLC9A4 SLC44A1 SLC44A5 SLC6A20 SLC47A1 SLC5A12 SLC26A11	6.34e-06	238	78	9	MM15076
Pathway	REACTOME_GPCR_LIGAND_BINDING	NPBWR1 DRD1 MCHR2 NPSR1 EDNRB CCKBR ADORA3 WNT16 SMO HRH3 CXCR1 CXCR2	8.29e-06	463	78	12	M507
Pathway	WP_NRF2_PATHWAY	ABCC3 SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20 SLC5A12	1.26e-05	141	78	7	M39454
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NPBWR1 DRD1 MCHR2 NPSR1 EDNRB CCKBR ADORA3 HRH3 CXCR1 CXCR2	1.32e-05	330	78	10	M18334
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NPBWR1 DRD1 NPSR1 TAAR3P EDNRB CCKBR ADORA3 HRH3 CXCR1 CXCR2	1.43e-05	333	78	10	MM14963
Pathway	REACTOME_SIGNALING_BY_GPCR	NPBWR1 DRD1 MCHR2 NPSR1 ADCY7 EDNRB CCKBR GPR83 ADORA3 WNT16 SMO HRH3 CXCR1 CXCR2	2.68e-05	702	78	14	M746
Pathway	KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION	ATP6V0E1 NOD1 ATP6V0E2 CXCR1 CXCR2	3.62e-05	68	78	5	M16848
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	NPBWR1 MCHR2 NPSR1 EDNRB CCKBR CXCR1 CXCR2	1.07e-04	197	78	7	M12289
Pathway	REACTOME_GPCR_LIGAND_BINDING	NPBWR1 DRD1 NPSR1 TAAR3P EDNRB CCKBR ADORA3 HRH3 CXCR1 CXCR2	1.24e-04	430	78	10	MM15160
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	NPBWR1 DRD1 MCHR2 EDNRB CCKBR GPR83 ADORA3 HRH3	1.26e-04	272	78	8	M13380
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A6 SLC6A13 SLC6A20	1.48e-04	19	78	3	M27362
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A6 SLC6A13 SLC6A20	1.48e-04	19	78	3	MM15107
Pathway	WP_GPCRS_OTHER	DRD1 OR1D2 GPR83 ADORA3 SMO	1.88e-04	96	78	5	MM15939
Pathway	REACTOME_SIGNALING_BY_GPCR	NPBWR1 DRD1 NPSR1 TAAR3P ADCY7 EDNRB CCKBR GPR83 ADORA3 HRH3 CXCR1 CXCR2	2.10e-04	646	78	12	MM14962
Pathway	WP_GPCRS_ODORANT	GPR137 ADGRG3 GPR135 TAAR3P GPR83 GPR137C	2.30e-04	157	78	6	MM15872
Pathway	WP_PROXIMAL_TUBULE_TRANSPORT	ATP6V0E1 SLC47A2 SLC6A20 SLC47A1	2.74e-04	57	78	4	M39812
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC6A6 SLC9A4 SLC6A20 SLC5A12 SLC26A11	3.26e-04	108	78	5	M823
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC6A6 SLC9A4 SLC6A20 SLC5A12 SLC26A11	3.40e-04	109	78	5	MM15074
Pathway	REACTOME_SYNTHESIS_OF_PC	BCHE SLC44A1 SLC44A5	4.83e-04	28	78	3	M684
Pathway	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	PTDSS1 TMEM86B BCHE SLC44A1 SLC44A5	7.09e-04	128	78	5	M706
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	NPBWR1 NPSR1 EDNRB CCKBR CXCR1 CXCR2	7.69e-04	197	78	6	MM14970
Pathway	WP_PEPTIDE_GPCRS	EDNRB CCKBR CXCR1 CXCR2	7.83e-04	75	78	4	M39696
Pathway	REACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS	SLC5A12 SLC26A11	1.06e-03	9	78	2	M27344
Pathway	REACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS	SLC5A12 SLC26A11	1.06e-03	9	78	2	MM15084
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	DRD1 TAAR3P HRH3	1.60e-03	42	78	3	MM14971
Pathway	KEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST	ALG10B ALG10	1.61e-03	11	78	2	M47614
Pathway	WP_NUCLEAR_RECEPTORS_METAPATHWAY	ABCC3 SLC6A16 SLC6A6 SLC6A8 SLC6A13 SLC6A20 SLC5A12	1.74e-03	314	78	7	M39428
Pathway	KEGG_ABC_TRANSPORTERS	ABCC3 ABCA9 ABCA5	1.83e-03	44	78	3	M11911
Pathway	KEGG_N_GLYCAN_BIOSYNTHESIS	MGAT4B ALG10B ALG10	2.08e-03	46	78	3	M11079
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP6V0E1 SLC17A3 TRPM2 ATP6V0E2 TRPV2	2.90e-03	176	78	5	MM15718
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	GPR137 ADGRG3 DRD1 NPSR1 GPR135 GPR137C GPR148	5.88e-09	79	109	7	12679517
Pubmed	Neurotransmitter transporter family including SLC6A6 and SLC6A13 contributes to the 5-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photodamage, through uptake of ALA by cancerous cells.	SLC6A6 SLC6A8 SLC6A13	2.99e-08	3	109	3	24842606
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	GPR137 TMEM94 NPSR1 CH25H NUP88 PTDSS1 GDPD2 CCKBR SLC6A8 G6PC3 ATP6V0E2 SMO SLC26A11 PIGM	4.12e-08	697	109	14	28298427
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	NPBWR1 DRD1 TAAR3P GNRHR2 ADORA3 HRH3 CXCR1 CXCR2	2.40e-07	200	109	8	18240029
Pubmed	The repertoire of solute carriers of family 6: identification of new human and rodent genes.	SLC6A6 SLC6A8 SLC6A13 SLC6A20	5.24e-07	21	109	4	16125675
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	ABCC3 SLC6A6 SLC6A13 SLC44A1 SLC6A20 CLDN5	1.03e-06	105	109	6	30280653
Pubmed	Dissociation of heterotrimeric g proteins in cells.	NPBWR1 EDNRB GNRHR2 ADORA3 HRH3 CXCR1 CXCR2	1.63e-06	179	109	7	18577758
Pubmed	Effects of CXCR1 and CXCR2 inhibition on expansion and differentiation of umbilical cord blood CD133(+) cells into megakaryocyte progenitor cells.	CXCR1 CXCR2	9.73e-06	2	109	2	21555225
Pubmed	Small interfering RNA-mediated CXCR1 or CXCR2 knock-down inhibits melanoma tumor growth and invasion.	CXCR1 CXCR2	9.73e-06	2	109	2	19585580
Pubmed	CXC chemokine receptor-1 is expressed by hepatocytes and regulates liver recovery after hepatic ischemia/reperfusion injury.	CXCR1 CXCR2	9.73e-06	2	109	2	21254176
Pubmed	Evaluation of 4',6-diamidino-2-phenylindole as a fluorescent probe substrate for rapid assays of the functionality of human multidrug and toxin extrusion proteins.	SLC47A2 SLC47A1	9.73e-06	2	109	2	20047987
Pubmed	Attenuation of murine allergic airway inflammation with a CXCR1/CXCR2 chemokine receptor inhibitor.	CXCR1 CXCR2	9.73e-06	2	109	2	30218547
Pubmed	Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs Modulates CXCR1/2 Expression and Activation in Cartilage Endplate Stem Cells to Induce Migration and Differentiation Toward a Pro-Inflammatory Phenotype.	CXCR1 CXCR2	9.73e-06	2	109	2	26302999
Pubmed	Elevated expression of the interleukin-8 receptors CXCR1 and CXCR2 in peripheral blood cells in obstructive coronary artery disease.	CXCR1 CXCR2	9.73e-06	2	109	2	21915051
Pubmed	The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.	CXCR1 CXCR2	9.73e-06	2	109	2	18668539
Pubmed	Expression of CXCR-1 and CXCR-2 chemokine receptors on synovial neutrophils in inflammatory arthritides: does persistent or increasing expression of CXCR-2 contribute to the chronic inflammation or erosive changes?	CXCR1 CXCR2	9.73e-06	2	109	2	16987681
Pubmed	Bronchoepithelial expression of CXCR1 and CXCR2 does not facilitate transepithelial migration of neutrophils.	CXCR1 CXCR2	9.73e-06	2	109	2	22076427
Pubmed	Intracellular trafficking of human CXCR1 and CXCR2: regulation by receptor domains and actin-related kinases.	CXCR1 CXCR2	9.73e-06	2	109	2	12442335
Pubmed	Roles of mechanical force and CXCR1/CXCR2 in shear-stress-induced endothelial cell migration.	CXCR1 CXCR2	9.73e-06	2	109	2	21989491
Pubmed	Molecular cloning and characterization of a novel form of the human vacuolar H+-ATPase e-subunit: an essential proton pump component.	ATP6V0E1 ATP6V0E2	9.73e-06	2	109	2	17350184
Pubmed	Different roles of CXCR1 and CXCR2 in HTLV-1 carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients.	CXCR1 CXCR2	9.73e-06	2	109	2	30341468
Pubmed	KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels.	KCNH1 ALG10	9.73e-06	2	109	2	9722534
Pubmed	Comparison of the genomic organization and promoter function for human interleukin-8 receptors A and B.	CXCR1 CXCR2	9.73e-06	2	109	2	7929358
Pubmed	CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration.	CXCR1 CXCR2	9.73e-06	2	109	2	21036625
Pubmed	[Effects of Xiaotan Sanjie Decoction on expressions of interleukin-8 and its receptors in gastric tumor xenografts and gastric tissue adjacent to the tumor in mice].	CXCR1 CXCR2	9.73e-06	2	109	2	20082763
Pubmed	The cytomegalovirus UL146 gene product vCXCL1 targets both CXCR1 and CXCR2 as an agonist.	CXCR1 CXCR2	9.73e-06	2	109	2	20044480
Pubmed	Lack of effect of the SLC47A1 and SLC47A2 gene polymorphisms on the glycemic response to metformin in type 2 diabetes mellitus patients.	SLC47A2 SLC47A1	9.73e-06	2	109	2	30433870
Pubmed	CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.	CXCR1 CXCR2	9.73e-06	2	109	2	26791948
Pubmed	Interleukin-8 in the human fallopian tube.	CXCR1 CXCR2	9.73e-06	2	109	2	11397869
Pubmed	Expression of interleukin-8 receptors in endometriosis.	CXCR1 CXCR2	9.73e-06	2	109	2	15618253
Pubmed	A human transporter protein that mediates the final excretion step for toxic organic cations.	SLC47A2 SLC47A1	9.73e-06	2	109	2	16330770
Pubmed	Intracellular cross-talk between the GPCR CXCR1 and CXCR2: role of carboxyl terminus phosphorylation sites.	CXCR1 CXCR2	9.73e-06	2	109	2	17996233
Pubmed	On the mechanism and significance of ligand-induced internalization of human neutrophil chemokine receptors CXCR1 and CXCR2.	CXCR1 CXCR2	9.73e-06	2	109	2	15028716
Pubmed	CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion.	CXCR1 CXCR2	9.73e-06	2	109	2	19401689
Pubmed	Functional characteristics of two human MATE transporters: kinetics of cimetidine transport and profiles of inhibition by various compounds.	SLC47A2 SLC47A1	9.73e-06	2	109	2	20067714
Pubmed	Rapid Regulation of Human Multidrug and Extrusion Transporters hMATE1 and hMATE2K.	SLC47A2 SLC47A1	9.73e-06	2	109	2	32708212
Pubmed	Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway.	DRD1 HRH3	9.73e-06	2	109	2	21173143
Pubmed	Association of interleukin-8 receptor alpha polymorphisms with chronic obstructive pulmonary disease and asthma.	CXCR1 CXCR2	9.73e-06	2	109	2	15772681
Pubmed	A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients.	CXCR1 CXCR2	9.73e-06	2	109	2	17360650
Pubmed	Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India.	CXCR1 CXCR2	9.73e-06	2	109	2	22171941
Pubmed	Low expression of CXCR1/2 on neutrophils predicts poor survival in patients with hepatitis B virus-related acute-on-chronic liver failure.	CXCR1 CXCR2	9.73e-06	2	109	2	27974825
Pubmed	Association between interleukin 8-receptor gene (CXCR1 and CXCR2) polymorphisms and urinary tract infection: Evidence from 4097 subjects.	CXCR1 CXCR2	9.73e-06	2	109	2	29577511
Pubmed	Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2.	CXCR1 CXCR2	9.73e-06	2	109	2	8384312
Pubmed	Association of CXCR1 and 2 expressions with gastric cancer metastasis in ex vivo and tumor cell invasion in vitro.	CXCR1 CXCR2	9.73e-06	2	109	2	25022956
Pubmed	Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients.	SLC47A2 SLC47A1	9.73e-06	2	109	2	20016398
Pubmed	The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations.	SLC47A2 SLC47A1	9.73e-06	2	109	2	16996621
Pubmed	Expression of both types of human interleukin-8 receptors on mature neutrophils, monocytes, and natural killer cells.	CXCR1 CXCR2	9.73e-06	2	109	2	7829970
Pubmed	CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis.	CXCR1 CXCR2	9.73e-06	2	109	2	26087179
Pubmed	The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin.	SLC47A2 SLC47A1	9.73e-06	2	109	2	23267855
Pubmed	Decreased CXCR1 and CXCR2 expression on neutrophils in anti-neutrophil cytoplasmic autoantibody-associated vasculitides potentially increases neutrophil adhesion and impairs migration.	CXCR1 CXCR2	9.73e-06	2	109	2	22152684
Pubmed	[Diagnostic efficiency of determining CXCR1, CXCR2 and hyaluronic acid blood level in non-small cell lung cancer patients].	CXCR1 CXCR2	9.73e-06	2	109	2	34730557
Pubmed	Phagocytosing neutrophils down-regulate the expression of chemokine receptors CXCR1 and CXCR2.	CXCR1 CXCR2	9.73e-06	2	109	2	12239185
Pubmed	Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors.	DRD1 HRH3	9.73e-06	2	109	2	19413572
Pubmed	Regulation of CXCR/IL-8 in human airway epithelial cells.	CXCR1 CXCR2	9.73e-06	2	109	2	20016196
Pubmed	Expression of CXC receptor 1 and 2 in esophageal mucosa of patients with reflux esophagitis.	CXCR1 CXCR2	9.73e-06	2	109	2	15793866
Pubmed	Human T lymphocytes and mast cells differentially express and regulate extra- and intracellular CXCR1 and CXCR2.	CXCR1 CXCR2	9.73e-06	2	109	2	15265017
Pubmed	CXCR1 and CXCR2 haplotypes synergistically modulate cystic fibrosis lung disease.	CXCR1 CXCR2	9.73e-06	2	109	2	22088968
Pubmed	Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil.	CXCR1 CXCR2	9.73e-06	2	109	2	26847910
Pubmed	Isoform-specific enhancement of adenylyl cyclase activity by n-alkanols.	DRD1 ADCY7	9.73e-06	2	109	2	17760784
Pubmed	Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs.	SLC47A2 SLC47A1	9.73e-06	2	109	2	27271370
Pubmed	Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity.	SLC47A2 SLC47A1	9.73e-06	2	109	2	19158817
Pubmed	Expression of CXCR1 and CXCR2 receptors in malignant melanoma with different metastatic potential and their role in interleukin-8 (CXCL-8)-mediated modulation of metastatic phenotype.	CXCR1 CXCR2	9.73e-06	2	109	2	14713106
Pubmed	Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes.	CXCR1 CXCR2	9.73e-06	2	109	2	27551720
Pubmed	Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters.	SLC47A2 SLC47A1	9.73e-06	2	109	2	17509534
Pubmed	[The role of CXCR1/2 in shear stress-induced endothelial cell migration].	CXCR1 CXCR2	9.73e-06	2	109	2	19634663
Pubmed	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	KCNH1 CXCR1 CXCR2	1.06e-05	14	109	3	23470693
Pubmed	Towards in situ tissue repair: human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2.	CXCR1 CXCR2	2.91e-05	3	109	2	17295203
Pubmed	CXCR1/2 inhibition enhances pancreatic islet survival after transplantation.	CXCR1 CXCR2	2.91e-05	3	109	2	22996693
Pubmed	Interleukin-8 receptors R1 and R2 activate mitogen-activated protein kinases and induce c-fos, independent of Ras and Raf-1 in Chinese hamster ovary cells.	CXCR1 CXCR2	2.91e-05	3	109	2	9843397
Pubmed	CXCR1 and CXCR2 silencing modulates CXCL8-dependent endothelial cell proliferation, migration and capillary-like structure formation.	CXCR1 CXCR2	2.91e-05	3	109	2	21749879
Pubmed	A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).	ALG10B ALG10	2.91e-05	3	109	2	24303013
Pubmed	Single nucleotide polymorphisms in the coding regions of human CXC-chemokine receptors CXCR1, CXCR2 and CXCR3.	CXCR1 CXCR2	2.91e-05	3	109	2	11196695
Pubmed	Structure and functional expression of a human interleukin-8 receptor.	CXCR1 CXCR2	2.91e-05	3	109	2	1840701
Pubmed	CXCR1 and CXCR2 activation and regulation. Role of aspartate 199 of the second extracellular loop of CXCR2 in CXCL8-mediated rapid receptor internalization.	CXCR1 CXCR2	2.91e-05	3	109	2	17204468
Pubmed	Molecular evolution of the human interleukin-8 receptor gene cluster.	CXCR1 CXCR2	2.91e-05	3	109	2	1303245
Pubmed	Association of single nucleotide polymorphisms in CXCR1, CXCR2 and CXCL5 with Behçet disease: a study in the Denizli province of Turkey.	CXCR1 CXCR2	2.91e-05	3	109	2	34050991
Pubmed	Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors.	CXCR1 CXCR2	2.91e-05	3	109	2	20630874
Pubmed	Dynamic regulation of CXCR1 and CXCR2 homo- and heterodimers.	CXCR1 CXCR2	2.91e-05	3	109	2	19890050
Pubmed	Genetic variation in interleukin 8 and its receptor genes and its influence on the risk and prognosis of prostate cancer among Finnish men in a large cancer prevention trial.	CXCR1 CXCR2	2.91e-05	3	109	2	16679868
Pubmed	The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities.	CXCR1 CXCR2	2.91e-05	3	109	2	15946947
Pubmed	The expression of interleukin-8 and interleukin-8 receptors in endometrial carcinoma.	CXCR1 CXCR2	2.91e-05	3	109	2	22626766
Pubmed	Monomer-dimer equilibria of interleukin-8 and neutrophil-activating peptide 2. Evidence for IL-8 binding as a dimer and oligomer to IL-8 receptor B.	CXCR1 CXCR2	2.91e-05	3	109	2	8195702
Pubmed	Neutrophil chemotaxis caused by chronic obstructive pulmonary disease alveolar macrophages: the role of CXCL8 and the receptors CXCR1/CXCR2.	CXCR1 CXCR2	2.91e-05	3	109	2	23912333
Pubmed	Characterization of two high affinity human interleukin-8 receptors.	CXCR1 CXCR2	2.91e-05	3	109	2	1379593
Pubmed	Analysis of the concentration of CXCL8 chemokine and its CXCR1 and CXCR2 receptors in peritoneal fluid of women with endometriosis.	CXCR1 CXCR2	2.91e-05	3	109	2	36086981
Pubmed	IL-8 gene variants are associated with lung function decline and multidimensional BODE index in COPD patients but not with disease susceptibility: a validation study.	CXCR1 CXCR2	2.91e-05	3	109	2	24946112
Pubmed	Inhibition of OCT2, MATE1 and MATE2-K as a possible mechanism of drug interaction between pazopanib and cisplatin.	SLC47A2 SLC47A1	2.91e-05	3	109	2	27178732
Pubmed	Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.	DRD1 HRH3	2.91e-05	3	109	2	24599455
Pubmed	The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases.	CXCR1 CXCR2	2.91e-05	3	109	2	24678812
Pubmed	Association between interleukin-8 gene alleles and human susceptibility to tuberculosis disease.	CXCR1 CXCR2	2.91e-05	3	109	2	12870115
Pubmed	Identification of biologically active peptides that inhibit binding of human CXCL8 to its receptors from a random phage-epitope library.	CXCR1 CXCR2	2.91e-05	3	109	2	19118103
Pubmed	Interleukin-8 is related to poor chemotherapeutic response and tumourigenicity in hepatocellular carcinoma.	CXCR1 CXCR2	2.91e-05	3	109	2	24161763
Pubmed	Inhibition of interleukin 8/C‑X-C chemokine receptor 1,/2 signaling reduces malignant features in human pancreatic cancer cells.	CXCR1 CXCR2	2.91e-05	3	109	2	29749433
Pubmed	A Preliminary Report of the Relationship Between Gene Polymorphism of IL-8 and Its Receptors and Systemic Inflammatory Response Syndrome Caused by Wasp Stings.	CXCR1 CXCR2	2.91e-05	3	109	2	31613654
Pubmed	Variants of the IL8 and IL8RB genes and risk for gastric cardia adenocarcinoma and esophageal squamous cell carcinoma.	CXCR1 CXCR2	2.91e-05	3	109	2	15598788
Pubmed	Characterization of chemokine receptors expressed in primitive blood cells during human hematopoietic ontogeny.	CXCR1 CXCR2	2.91e-05	3	109	2	11007922
Pubmed	The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma.	CXCR1 CXCR2	2.91e-05	3	109	2	26267317
Pubmed	[Influence of IFN on expression of chemokine receptor CXCR1, CXCR2 and their ligand IL-8 in the patients with chronic hepatitis B].	CXCR1 CXCR2	2.91e-05	3	109	2	22482416
Pubmed	Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2.	CXCR1 CXCR2	2.91e-05	3	109	2	31666007
Pubmed	CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study.	CXCR1 CXCR2	2.91e-05	3	109	2	20089160
Interaction	TTYH1 interactions	DPY19L3 PCNX3 TMEM94 PIEZO1 LMBRD2 THEM6 SLC44A1 SLC44A5 ALG10 SLC47A1 SMO XPR1 PIGM	2.68e-09	300	99	13	int:TTYH1
Interaction	C3orf52 interactions	MGAT4B ADGRG3 PCNX3 TMEM94 PIEZO1 AMIGO1 THEM6 ABCA5 SMO ATG9A XPR1	3.08e-07	305	99	11	int:C3orf52
Interaction	SLC17A2 interactions	SLC17A2 PCNX3 TMEM94 SLC47A1 ATG9A	8.09e-06	56	99	5	int:SLC17A2
Interaction	UPK1A interactions	SLC44A1 LMF2 SLC44A5 ALG10 SLC47A1 XPR1 PIGM	9.24e-06	150	99	7	int:UPK1A
Interaction	TNFRSF10C interactions	TMEM94 SLC6A6 SLC6A8 SLC44A1 SLC44A5 SLC47A1	1.17e-05	103	99	6	int:TNFRSF10C
Interaction	OR10H2 interactions	PCNX3 SLC44A1 SMO ATG9A XPR1	2.79e-05	72	99	5	int:OR10H2
Interaction	CD79A interactions	MYADM CYB561D2 TMEM86B OTOP2 ALG10B TMEM229B ALG10 TMEM86A	4.53e-05	262	99	8	int:CD79A
Interaction	HTR3C interactions	LMF2 ALG10 TMEM59L SLC47A1 PIGM	7.33e-05	88	99	5	int:HTR3C
Interaction	PTH1R interactions	PCNX3 SLC44A1 ALG10 SLC47A1 PIGM	7.33e-05	88	99	5	int:PTH1R
Interaction	PSCA interactions	CYB561D2 TMEM86B BCHE SLC44A1 SLC44A5 LARGE1	8.72e-05	147	99	6	int:PSCA
Interaction	TM2D2 interactions	PCNX3 SLC47A1 PIGM	1.43e-04	21	99	3	int:TM2D2
Interaction	CRELD1 interactions	ABCC3 PIEZO1 LMBRD2 ALG10B LMF2 ALG10	1.54e-04	163	99	6	int:CRELD1
Interaction	CMTM5 interactions	PIEZO1 LMBRD2 SLC6A8 SLC44A1 ALG10 MCEMP1 PIGM	1.78e-04	239	99	7	int:CMTM5
Interaction	HTR3A interactions	PCNX3 LMF2 TMEM59L SLC47A1 ATG9A	1.93e-04	108	99	5	int:HTR3A
Interaction	HRH3 interactions	DRD1 HRH3	2.37e-04	5	99	2	int:HRH3
Interaction	YIPF3 interactions	MGAT4B PCNX3 PIEZO1 GPR52 SLC6A8 ALG10	3.14e-04	186	99	6	int:YIPF3
Interaction	GABRA3 interactions	AMIGO1 TMEM59L SLC47A1	3.45e-04	28	99	3	int:GABRA3
Interaction	ZDHHC12 interactions	PCNX3 TMEM94 ADCY7 THEM6 ATG9A	3.53e-04	123	99	5	int:ZDHHC12
Cytoband	21q22.3	TRPM2 LINC00479 PSMG1 TRAPPC10	2.56e-04	128	109	4	21q22.3
GeneFamily	Solute carriers	SLC17A2 SLC17A3 SLC6A16 SLC47A2 SLC6A6 SLC6A8 SLC6A13 SLC9A4 SLC44A1 SLC44A5 SLC25A15 SLC6A20 SLC47A1 SLC5A12 SLC26A11	6.55e-11	395	75	15	752
GeneFamily	G protein-coupled receptors, Class A orphans	MRGPRD GPR135 GPR52 GPR83 GPR174 GPR148	8.43e-07	78	75	6	262
GeneFamily	Alpha-1,2-glucosyltransferases	ALG10B ALG10	1.70e-05	2	75	2	448
GeneFamily	CD molecules\|C-X-C motif chemokine receptors	CXCR1 CXCR2	2.52e-04	6	75	2	1094
GeneFamily	Neuropeptide receptors	NPBWR1 NPSR1	7.48e-04	10	75	2	854
GeneFamily	ATP binding cassette subfamily A	ABCA9 ABCA5	1.50e-03	14	75	2	805
GeneFamily	V-type ATPases	ATP6V0E1 ATP6V0E2	4.06e-03	23	75	2	415
GeneFamily	Transient receptor potential cation channels	TRPM2 TRPV2	5.99e-03	28	75	2	249
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 SLC17A3 TMEM86B BCHE SLC6A13 SLC25A15 SLC47A1	1.17e-07	156	109	7	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCC3 ADGRG3 FMR1NB CH25H DCST1	2.54e-06	88	109	5	52d4e572e6800eaa073ef62adaf4e42882ce1eed
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCC3 ADGRG3 FMR1NB CH25H DCST1	2.54e-06	88	109	5	eadf8f0fb1181c504942c48d55d309ca4e5f6485
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	ABCC3 ADGRG3 FMR1NB CH25H DCST1	2.54e-06	88	109	5	72b789cbccce675f37e0553f63df93643af12b4e
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ABCC3 SLC17A3 ST8SIA1 SLC6A13 KCNH1	3.53e-06	167	109	6	ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD2 GPR52 ST8SIA1 TMEM229B ABCA5 PCNX1	5.09e-06	178	109	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BCHE GPR83 ELFN1 SLC47A1 PCDH8 HRH3	5.60e-06	181	109	6	70eff83dd85691e977972c660731394d2fcf5cdf
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIEZO1 SLC47A2 OR1D2 LMF2 GPR137C LARGE1	6.16e-06	184	109	6	af6522586d012e91241f3e06c60f9d1881e95646
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	6.75e-06	187	109	6	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	6.75e-06	187	109	6	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	wk_15-18-Hematologic-Myeloid-Basophil\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADGRG3 PCNX3 TRPM2 GPR174 TRPV2 CXCR1	6.96e-06	188	109	6	3638d85452de15a060146628fbbad9d2a36feb13
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT4B CH25H SLC6A6 SLC9A4 CLMN MCEMP1	7.18e-06	189	109	6	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A6 SLC6A13 SLC47A1 SLC5A12	7.18e-06	189	109	6	28b502611829e4a24caff2562545c7db97686099
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT4B CH25H SLC6A6 SLC9A4 CLMN MCEMP1	7.40e-06	190	109	6	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GPR137 VPS50 SCD5 ALG10 CXCR2 PIGM	7.62e-06	191	109	6	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	facs-Brain_Non-Myeloid-Striatum\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRD1 ASPHD2 SCD5 GPR83 SLC44A1 HRH3	8.09e-06	193	109	6	d8ccfb780a75bdf9141f41fb29a076958601ebb4
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DRD1 ASPHD2 SCD5 GPR83 SLC44A1 HRH3	8.33e-06	194	109	6	ba529c051f248d29f4222f4bc9801ba233859093
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MYADM ADGRG3 SLC6A6 MCEMP1 CXCR1 CXCR2	9.63e-06	199	109	6	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MYADM ADGRG3 SLC6A6 MCEMP1 CXCR1 CXCR2	9.91e-06	200	109	6	b665f36dcf3c9d3981ee96f2973512f751612542
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 SLC17A3 TMEM86B BCHE SLC25A15	2.36e-05	139	109	5	82bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 SLC17A3 TMEM86B BCHE SLC25A15	2.36e-05	139	109	5	fc9ac09c2106e88104a52575832d71d17765eec8
ToppCell	facs-Liver-Hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 SLC17A3 TMEM86B BCHE SLC25A15	2.36e-05	139	109	5	fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 SLC17A3 TMEM86B BCHE SLC25A15	2.36e-05	139	109	5	4ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ST8SIA1 TMEM229B SLC6A13 GPR174 SLC25A15	3.30e-05	149	109	5	efa30fcd9370f98eb7445f295eb4d0305ff455c3
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 SLC6A13 MCEMP1 CXCR1 CXCR2	4.23e-05	157	109	5	320d5ac063fd90e26f537475c328b3ae73974bc1
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADCY7 GPR83 ODF4 ELFN1 WNT16	4.23e-05	157	109	5	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM2 SLC6A13 MCEMP1 CXCR1 CXCR2	4.23e-05	157	109	5	e4b17c267b754c5af95cdf17f629354d1a8a8ad7
ToppCell	facs-Skin-Anagen-3m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ASPHD2 EDNRB ATP6V0E2 CLDN5	4.77e-05	161	109	5	8d2987271da52fd8353557ac6faa4f7a4be0ed2a
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|367C / Donor, Lineage, Cell class and subclass (all cells)	VPS50 SCD5 ALG10 CXCR2 PIGM	4.77e-05	161	109	5	f470b662566131dfe69a2fd01186ac8491196396
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYADM TMEM86B SLC6A6 GPR137C CLDN5	5.06e-05	163	109	5	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	facs-Spleen-nan-18m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMR1NB CH25H GDPD2 CERS3 MCEMP1	5.52e-05	166	109	5	8d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCell	facs-Spleen-nan-18m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMR1NB CH25H GDPD2 CERS3 MCEMP1	5.52e-05	166	109	5	f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCell	facs-Spleen-nan-18m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMR1NB CH25H GDPD2 CERS3 MCEMP1	5.52e-05	166	109	5	a5074c96c6561273029aceb93402a7e038140f50
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B ADGRG3 GPR135 CLDN5 FBXO33	5.68e-05	167	109	5	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B ADGRG3 GPR135 CLDN5 FBXO33	5.68e-05	167	109	5	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B ADGRG3 GPR135 CLDN5 FBXO33	5.68e-05	167	109	5	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT4B ADGRG3 GPR135 CLDN5 FBXO33	5.68e-05	167	109	5	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	facs-Kidney\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A3 SLC6A13 SLC6A20 SLC47A1 SLC5A12	5.84e-05	168	109	5	d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCell	droplet-Kidney-nan-18m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ABCC3 SLC17A3 ST8SIA1 SLC6A13	6.01e-05	169	109	5	f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell	droplet-Kidney-nan-21m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ABCC3 SLC17A3 ST8SIA1 SLC6A13	6.35e-05	171	109	5	007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ABCC3 SLC17A3 ST8SIA1 SLC6A13	6.35e-05	171	109	5	8e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	6.35e-05	171	109	5	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	6.71e-05	173	109	5	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 ADCY7 TMEM229B ADORA3 TRPV2	7.47e-05	177	109	5	7853430fb0d1a18d835e8956777e0616c5d7d412
ToppCell	facs-Skin-Anagen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 ADCY7 TMEM229B ADORA3 TRPV2	7.47e-05	177	109	5	395f005f019aabb18738d3a10a04c37f216deda3
ToppCell	facs-Skin-Anagen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 ADCY7 TMEM229B ADORA3 TRPV2	7.47e-05	177	109	5	9a5bf67a801826d094f679dd2189b62296c9694f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 DENND1B CLMN ELFN1 KNDC1	7.47e-05	177	109	5	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	7.68e-05	178	109	5	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRG3 ST8SIA1 MCEMP1 CXCR1 CXCR2	7.68e-05	178	109	5	af9bcee71fb44a6342d4b92bba5b8ddfeeaa24b2
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ADGRG3 FMR1NB CH25H SLC9A4	7.73e-05	92	109	4	ed282f0f3da1593bdec5a2b20af5b8f058574167
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ADGRG3 FMR1NB CH25H SLC9A4	7.73e-05	92	109	4	c5f30d58f235f7a72dfe63f58999c4680502576f
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ADGRG3 FMR1NB CH25H SLC9A4	7.73e-05	92	109	4	27072dbf6819dca41e41267dc250abfaaf175b2f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	7.88e-05	179	109	5	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 GPR135 SLC6A13 SLC47A1 SLC5A12	7.88e-05	179	109	5	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.09e-05	180	109	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.09e-05	180	109	5	1363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages\|bone_marrow / Manually curated celltypes from each tissue	VPS50 EDNRB SLC6A8 ADORA3 TMEM86A	8.09e-05	180	109	5	daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.09e-05	180	109	5	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.30e-05	181	109	5	9542c19edc9bd2cba68c01c2a8407705398e3011
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.30e-05	181	109	5	8f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.30e-05	181	109	5	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC6A13 SLC6A20 SLC47A1 SLC5A12	8.52e-05	182	109	5	e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC17A2 SCD5 ABCA5 CERS3 TMEM59L	8.52e-05	182	109	5	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC6A13 SLC6A20 SLC47A1 SLC5A12	8.52e-05	182	109	5	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC17A2 SCD5 ABCA5 CERS3 TMEM59L	8.52e-05	182	109	5	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT4B SLC6A6 SLC9A4 CLMN MCEMP1	8.52e-05	182	109	5	be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC6A13 SLC6A20 SLC47A1 SLC5A12	8.52e-05	182	109	5	57bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.75e-05	183	109	5	facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC3 SLC17A3 SLC47A2 SLC6A13 SLC6A20	8.75e-05	183	109	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.75e-05	183	109	5	84b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	8.97e-05	184	109	5	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC6A13 SLC6A20 SLC47A1 SLC5A12	8.97e-05	184	109	5	9434731f651820b05335085582960f08fbf895de
ToppCell	wk_15-18-Hematologic-Myeloid-Myelocyte-like\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SCN11A ADGRG3 TMEM86B MCEMP1 CXCR2	9.20e-05	185	109	5	92b9ec18ff7c53a52b87e2c2012d0b719a7ad20a
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.20e-05	185	109	5	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.44e-05	186	109	5	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC6A13 SLC6A20 SLC47A1 SLC5A12	9.44e-05	186	109	5	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC47A2 LINC00479 SLC6A6 SLC6A13	9.44e-05	186	109	5	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.68e-05	187	109	5	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.68e-05	187	109	5	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.68e-05	187	109	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC3 SLC17A3 SLC47A2 SLC47A1 SLC5A12	9.68e-05	187	109	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.68e-05	187	109	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.68e-05	187	109	5	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.68e-05	187	109	5	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.93e-05	188	109	5	f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	9.93e-05	188	109	5	0792432cd4c564dea1102241ea9884f7ced7658c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT4B CH25H SLC6A6 SLC9A4 CLMN	1.02e-04	189	109	5	287e59104687fe1665232c52993889f0f2c97f17
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	1.02e-04	189	109	5	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	droplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT4B CH25H SLC6A6 SLC9A4 CLMN	1.02e-04	189	109	5	6d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	1.02e-04	189	109	5	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC3 SLC17A3 SLC47A2 SLC47A1 SLC5A12	1.02e-04	189	109	5	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR137 VPS50 SCD5 ALG10 PIGM	1.04e-04	190	109	5	2434b8ad2976eab7d9147012c28454ab29670709
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 SCD5 SLC6A13 G6PC3 PSMG1	1.04e-04	190	109	5	a1b5775a21d42633224b7d348f0d12b0589dad12
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	1.07e-04	191	109	5	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC17A3 SLC47A2 SLC6A13 SLC47A1 SLC5A12	1.07e-04	191	109	5	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	severe-Myeloid-Neutrophils_3\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SLC6A6 PCNX1 MCEMP1 CXCR1 CXCR2	1.15e-04	194	109	5	1f8edab1c8ba48bc0114429ea47aab378b5830b7
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 CH25H ADCY7 ADORA3 MFSD1	1.15e-04	194	109	5	abce1e824ce2512741c313a5ec336d12f580b093
ToppCell	mild-Myeloid-Neutrophils_1\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MYADM ADGRG3 SLC6A6 CXCR1 CXCR2	1.15e-04	194	109	5	ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYADM ADGRG3 MCEMP1 CXCR1 CXCR2	1.15e-04	194	109	5	607b5d194ba56efa9b106f10f89368fc103712a0
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 CH25H ADCY7 ADORA3 MFSD1	1.15e-04	194	109	5	6810586080cc893e3270b9c8bee2d95ed78e2893
Drug	Protons	BCHE SLC47A2 SLC9A4 SLC47A1	2.69e-06	21	108	4	ctd:D011522
Drug	sodium	SLC17A2 ABCC3 SLC17A3 SLC6A16 TRPM2 BCHE ADCY7 SLC6A6 SLC6A13 KCNH1 SLC25A15 SLC6A20 SLC47A1 CLDN5 SLC5A12 SLC26A11	9.56e-06	944	108	16	CID000000923
Drug	cinchonidine	SLC47A2 SLC47A1	2.23e-05	2	108	2	ctd:C041622
Drug	ethohexadiol	SLC47A2 SLC47A1	2.23e-05	2	108	2	ctd:C004917
Drug	Sulfamerazine	SLC47A2 SLC47A1	2.23e-05	2	108	2	ctd:D013416
Drug	triethylmethylammonium	SLC47A2 SLC47A1	2.23e-05	2	108	2	ctd:C043900
Drug	Midodrine	SLC47A2 SLC47A1	2.23e-05	2	108	2	ctd:D008879
Drug	Nialamide	SLC47A2 SLC47A1	2.23e-05	2	108	2	ctd:D009526
Drug	cimetidine	ABCC3 SLC47A2 ADCY7 CCKBR SLC47A1 SLC5A12 HRH3	2.36e-05	179	108	7	CID000002756
Drug	fexofenadine	ABCC3 SLC47A2 KCNH1 SLC47A1 HRH3	2.54e-05	73	108	5	CID000003348
Drug	probenecid	ABCC3 SLC47A2 ADCY7 TRPV2 SLC47A1 SLC5A12	2.68e-05	123	108	6	CID000004911
Drug	BE-I	ABCC3 MCHR2 SLC6A6 SMO	2.80e-05	37	108	4	CID000445303
Drug	octanal	DRD1 OR1D2 KCNH1 OR52A1	2.80e-05	37	108	4	CID000000454
Drug	3-isoreserpine	ABCC3 DRD1 ABCA9 ADCY7 EDNRB ABCA5 KCNH1	3.46e-05	190	108	7	CID000005052
Drug	tetradotoxin	SCN11A DRD1 MRGPRD BCHE EDNRB CCKBR SLC6A13 ADORA3 TRPV2 HRH3	3.73e-05	428	108	10	CID000020382
Drug	ketanserin	DRD1 ADCY7 CCKBR ADORA3 SLC6A20 HRH3	3.83e-05	131	108	6	CID000003822
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A	GPR137 VPS50 SCD5 ADCY7 SLC6A6 LMF2 LARGE1	4.21e-05	196	108	7	1494_UP
Drug	Prochlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; PC3; HT_HG-U133A	SCN11A PRAMEF12 OR1D2 ADORA3 SLC6A20 SMO CXCR2	4.35e-05	197	108	7	6664_UP
Drug	A 86929	DRD1 EDNRB CCKBR	4.53e-05	15	108	3	ctd:C095427
Drug	diaminocyclobut-3-ene-1,2-dione	CXCR1 CXCR2	6.67e-05	3	108	2	CID002781329
Drug	5-methoxysalicylaldehyde	CXCR1 CXCR2	6.67e-05	3	108	2	CID000095695
Drug	DTTA	CXCR1 CXCR2	6.67e-05	3	108	2	CID000166909
Drug	Ionophores	CXCR1 CXCR2	6.67e-05	3	108	2	ctd:D007476
Drug	dimethylcyclohexane	CXCR1 CXCR2	6.67e-05	3	108	2	CID000011549
Disease	Long Qt Syndrome 2	ALG10B ALG10	3.61e-05	3	103	2	C3150943
Disease	Ulcerative Colitis	ADCY7 PSMG1 CXCR1 CXCR2	7.12e-05	63	103	4	C0009324
Disease	nonsyndromic deafness (implicated_via_orthology)	ALG10B ALG10	1.79e-04	6	103	2	DOID:0050563 (implicated_via_orthology)
Disease	leptin measurement	NPBWR1 DRD1 ALG10B ALG10	1.90e-04	81	103	4	EFO_0005000
Disease	amnestic disorder (implicated_via_orthology)	BCHE HRH3	4.28e-04	9	103	2	DOID:10914 (implicated_via_orthology)
Disease	serum ST2 measurement	SLC9A4 DENND1B	6.50e-04	11	103	2	EFO_0005416
Disease	colitis (implicated_via_orthology)	CCKBR CXCR2	9.18e-04	13	103	2	DOID:0060180 (implicated_via_orthology)
Disease	serum amyloid A-1 protein measurement	BCHE TMEM86A	1.78e-03	18	103	2	EFO_0008282
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	CCKBR ELFN1	3.17e-03	24	103	2	EFO_0003948, EFO_0009923, MONDO_0004247
Disease	FEV change measurement, response to zileuton	PCNX1 LMBRD1	3.44e-03	25	103	2	EFO_0005921, EFO_0007676

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRWILACCLFLSVLV	TMEM59L	266	Q9UK28
VISPYLQCVLWIFLL	ABCA5	1211	Q8WWZ7
CYPQAWILACSAALL	LINC00479	66	Q96M42
LVLIYLYLTPCRCWC	AMIGO1	386	Q86WK6
TIICIRFLFWFLLLC	BCHE	6	P06276
PFYCSCELLGFLRWL	ELFN1	191	P0C7U0
PLSCFLVALIIWCYL	CCSMST1	81	Q4G0I0
LSWLPLSIINCIIYF	ADORA3	241	P0DMS8
YTRLPAFLEWTLCLL	ABCA9	351	Q8IUA7
FICCWFTILYLPSQS	ADGRG3	516	Q86Y34
FCLVLVFALCWLPLH	EDNRB	326	P24530
FCLTWPYILLGFLFC	ALG10B	251	Q5I7T1
SVPILILLYLCYKFW	DPY19L3	526	Q6ZPD9
FVCCWLPFFILNCIL	DRD1	281	P21728
ALVAYLVLFNLSPCW	ADCY7	751	P51828
LVIVVLFFLCWLPVY	CCKBR	336	P32239
CFQNSLLAWVPCIYL	ABCC3	31	O15438
GWLVLILYFTCAILC	ODF4	186	Q2M2E3
CCLLWFVVIYDDPVS	SLC17A3	166	O00476
LSLLCIPAITWIYLF	LARGE1	16	O95461
VAYILLCCWCIKELL	LENEP	46	Q9Y5L5
LLLFCLCAFLSLSWY	MGAT4B	11	Q9UQ53
SIIIILAFICCWSPY	NPSR1	276	Q6W5P4
WLLYCCPVCLQFFTL	GPR137	96	Q96N19
CIFGLLLLAILAFCW	LMBRD1	16	Q9NUN5
YQSLCLFLCLLWAAL	GPR137C	81	Q8N3F9
IFNFLKYTLWPCLVL	G6PC3	311	Q9BUM1
CLFYPALWPQLRICL	FBXO33	101	Q7Z6M2
AVLYQACCVALLLWL	MFSD6L	521	Q8IWD5
RPVYFCICCGLIWLL	PCNX1	1071	Q96RV3
YFCICCLLIWLLDAL	PCNX3	861	Q9H6A9
QFWLAFPLCSLYLIA	OR51E1	26	Q8TCB6
HVWISIPVCCLYTIA	OR51T1	26	Q8NGJ9
QCWIGIPFCAIYLIA	OR52A1	26	Q9UKL2
CLFPLQLFSLCWVLS	PCDH8	11	O95206
LLCWLPYNLVLLADT	CXCR2	261	P25025
LICSLPLSIYWFVLY	MRGPRD	231	Q8TDS7
SLCSVPLFCWIIFRC	NOD1	386	Q9Y239
YLKTWFVIDLLSCLP	KCNH1	291	O95259
PALEWCVAVYAICFI	MYADM	201	Q96S97
DFSLPLWLIFIICVC	MFSD1	261	Q9H3U5
CDCIWFGLLFLTFLL	GDPD2	36	Q9HCC8
YISIAGWLIICLACV	GPR174	136	Q9BXC1
CIILIWIYSCLIFLP	GPR52	161	Q9Y2T5
LVVVLFALCWFPLNC	GPR83	296	Q9NYM4
FALCWFPLNCYVLLL	GPR83	301	Q9NYM4
WILFYLLRTVRCPCA	OTOP2	76	Q7RTS6
FLWFIAPIYACVCRI	GTSCR1	81	Q86UQ5
IGWTPFLCIVLSYIC	OR5V1	206	Q9UGF6
SYCQVWKIPAILYLC	PSMG1	221	O95456
PLILVCYILILCYTW	MCHR2	211	Q969V1
CCPWELSILIRFAPY	PRAMEF12	211	O95522
VITVACLLVLFVWYC	ASPHD2	61	Q6ICH7
LIVFPFWILYCTLIL	CERS3	276	Q8IU89
LQFLPELIWCYLAVS	FAM126A	76	Q9BYI3
ICCWGPYCFLVLLAA	GPR135	341	Q8IZ08
YWRAAVPIGLLVCLC	DCST1	551	Q5T197
CPLILIWQILYAFFS	ATG9A	301	Q7Z3C6
LIWLVACCFPTFLIW	GPR148	171	Q8TDV2
AVVLIFLLCWLPYNL	CXCR1	246	P25024
FLLCWLPYNLVLLAD	CXCR1	251	P25024
LCKLWLVVDYLLCTS	HRH3	106	Q9Y5N1
PCWLYRAILSLYILL	MCEMP1	76	Q8IX19
PFREYELWALCLACL	KNDC1	456	Q76NI1
CTDIPWLLLFILFCI	SLC44A1	26	Q8WWI5
LTFILLSICICYWVV	SLC44A5	376	Q8NCS7
ILVCLPIYCRSLFWR	FMR1NB	196	Q8N0W7
GTICLCILSYLPWFE	DENND1B	91	Q6P3S1
AWYLAVLCPVLTSLV	CYB561D2	191	O14569
FCLPFVVLDILCSWV	CH25H	51	O95992
ILAVCLLCWTPYHLS	NPBWR1	256	P48145
ICITSTYECLIWPLL	NUP88	481	Q99567
CILLLSLCWVLSVLY	OR1D2	141	P34982
ILYAVFCLPSWEARL	OR52E8	226	Q6IFG1
LACWLPCFLAVLIDP	TAAR3P	266	Q9P1P4
VCCYLFWLIAILAQL	ATP6V0E1	46	O15342
ALCLLLVWLVCFFCI	SLC6A6	221	P31641
YSLVLPFFLCWCLVG	SLC6A16	266	Q9GZN6
ALVLLLCCLPCWALF	SLC47A2	116	Q86VL8
FALLDVWYLVRLPCA	THEM6	16	Q8WUY1
CPLLLRCLIYTLWTY	TMEM229B	71	Q8NBD8
PVIYLLLWAAYLSAC	LMF2	101	Q9BU23
AWYLCFLIVFILPLD	LMBRD2	41	Q68DH5
LILLTFILCWTPYYL	GNRHR2	181	Q96P88
FVTYSPWNCLLLLVA	SLC9A4	6	Q6AI14
GASALCVVVLCWLYI	ST8SIA1	31	Q92185
CVVVLCWLYIFPVYR	ST8SIA1	36	Q92185
KPLTLLWAYFCFLLA	SCD5	71	Q86SK9
TLCLLACWVLVYFCV	SLC6A8	236	P48029
ICLWLAVYPVDCIKS	SLC25A15	221	Q9Y619
ALCLLLAWLVVYLCI	SLC6A20	171	Q9NP91
LVLLLCCFPCWALFL	SLC47A1	121	Q96FL8
LLLTWPYILLGFLFC	ALG10	251	Q5BKT4
LFCGLLALVPLCWFA	CLDN5	126	O00501
ILFLWLLVYCLLLFP	CLMN	981	Q96JQ2
LWCLSLLACFFAPIS	XPR1	326	Q9UBH6
YIPCLADLCKALWEV	VPS50	321	Q96JG6
LIKCLPIFCLWLFLL	TMEM86A	41	Q8N2M4
LPLCVTFLLCFWEVQ	SLC26A11	436	Q86WA9
TTDILWLSCFCYPLL	TMEM94	1121	Q12767
WLSCFCYPLLSISLL	TMEM94	1126	Q12767
PEWLTVLLLCLYLLF	TRPM2	1021	O94759
LIKYCWLFLTPAVCT	SLC6A13	491	Q9NSD5
CVCCLLWFTVIYDDP	SLC17A2	221	O00624
VLCFLAIEWYLPLLV	TRPV2	486	Q9Y5S1
RLCALWAALLVLFPY	WNT16	11	Q9UBV4
VCRWLSPFILSCCVY	TMEM86B	21	Q8N661
SPFILSCCVYFCLWI	TMEM86B	26	Q8N661
LVATAVCCYLFWLIA	ATP6V0E2	41	Q8NHE4
VCCYLFWLIAILAQL	ATP6V0E2	46	Q8NHE4
PRCWAVIQPLLCAVY	SMO	116	Q99835
VLLVCLIFWLVFCIL	SCN11A	1181	Q9UI33
YWLLLPCALLAACLL	PIEZO1	11	Q92508
RLWPNYCLFLALFLL	PIEZO1	1036	Q92508
LLTFPFLHIYWTECC	TRAPPC10	81	P48553
PLLIRPVCNLFCFWS	SLC5A12	536	Q1EHB4
CTSQYFLWYLCLLPL	PIGM	331	Q9H3S5
LWLLCVAFTTFLCLY	PTDSS1	386	P48651