| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | RNA nuclease activity | 3.29e-05 | 136 | 54 | 5 | GO:0004540 | |
| GeneOntologyMolecularFunction | nuclease activity | 3.65e-05 | 231 | 54 | 6 | GO:0004518 | |
| GeneOntologyMolecularFunction | hydrolase activity, acting on ester bonds | DXO ZC3H12A THEM4 CTDSPL2 CNOT7 NT5C2 ZC3H12B ZC3H12C PLCH1 CNOT8 | 5.24e-05 | 807 | 54 | 10 | GO:0016788 |
| GeneOntologyMolecularFunction | exonuclease activity | 1.12e-04 | 92 | 54 | 4 | GO:0004527 | |
| GeneOntologyMolecularFunction | catalytic activity, acting on RNA | 1.25e-04 | 417 | 54 | 7 | GO:0140098 | |
| GeneOntologyMolecularFunction | RNA exonuclease activity | 2.45e-04 | 45 | 54 | 3 | GO:0004532 | |
| GeneOntologyMolecularFunction | poly(A)-specific ribonuclease activity | 5.49e-04 | 13 | 54 | 2 | GO:0004535 | |
| GeneOntologyMolecularFunction | RNA endonuclease activity | 1.28e-03 | 79 | 54 | 3 | GO:0004521 | |
| GeneOntologyMolecularFunction | catalytic activity, acting on a nucleic acid | 1.68e-03 | 645 | 54 | 7 | GO:0140640 | |
| GeneOntologyCellularComponent | CCR4-NOT core complex | 9.76e-05 | 6 | 54 | 2 | GO:0030015 | |
| GeneOntologyCellularComponent | cytoplasmic ribonucleoprotein granule | 6.43e-04 | 269 | 54 | 5 | GO:0036464 | |
| GeneOntologyCellularComponent | CCR4-NOT complex | 7.68e-04 | 16 | 54 | 2 | GO:0030014 | |
| GeneOntologyCellularComponent | ribonucleoprotein granule | 8.60e-04 | 287 | 54 | 5 | GO:0035770 | |
| Domain | NUT | 1.67e-13 | 5 | 54 | 5 | IPR024310 | |
| Domain | NUT_N | 1.67e-13 | 5 | 54 | 5 | IPR024309 | |
| Domain | NUT | 1.67e-13 | 5 | 54 | 5 | PF12881 | |
| Domain | RNase_Zc3h12a | 7.93e-07 | 7 | 54 | 3 | PF11977 | |
| Domain | RNase_Zc3h12_NYN | 7.93e-07 | 7 | 54 | 3 | IPR021869 | |
| Domain | CAF1 | 8.16e-05 | 5 | 54 | 2 | PF04857 | |
| Domain | RNase_CAF1 | 8.16e-05 | 5 | 54 | 2 | IPR006941 | |
| Domain | ZF_C3H1 | 6.30e-04 | 58 | 54 | 3 | PS50103 | |
| Domain | IQ | 1.14e-03 | 71 | 54 | 3 | PF00612 | |
| Domain | IQ_motif_EF-hand-BS | 2.25e-03 | 90 | 54 | 3 | IPR000048 | |
| Domain | IQ | 2.47e-03 | 93 | 54 | 3 | PS50096 | |
| Domain | Ion_trans_dom | 4.38e-03 | 114 | 54 | 3 | IPR005821 | |
| Domain | Ion_trans | 4.38e-03 | 114 | 54 | 3 | PF00520 | |
| Domain | Myosin_head_motor_dom | 5.40e-03 | 38 | 54 | 2 | IPR001609 | |
| Domain | MYOSIN_MOTOR | 5.40e-03 | 38 | 54 | 2 | PS51456 | |
| Domain | Myosin_head | 5.40e-03 | 38 | 54 | 2 | PF00063 | |
| Domain | MYSc | 5.40e-03 | 38 | 54 | 2 | SM00242 | |
| Pubmed | A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages. | 1.58e-08 | 4 | 56 | 3 | 18178554 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 19605561 | ||
| Pubmed | Conservation of the deadenylase activity of proteins of the Caf1 family in human. | 2.55e-06 | 2 | 56 | 2 | 15769875 | |
| Pubmed | 2.55e-06 | 2 | 56 | 2 | 34298932 | ||
| Pubmed | CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex. | 2.55e-06 | 2 | 56 | 2 | 35248544 | |
| Pubmed | CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells. | 7.63e-06 | 3 | 56 | 2 | 20065043 | |
| Pubmed | The CCR4-NOT complex suppresses untimely translational activation of maternal mRNAs. | 7.63e-06 | 3 | 56 | 2 | 37767629 | |
| Pubmed | 7.63e-06 | 3 | 56 | 2 | 22456610 | ||
| Pubmed | 7.63e-06 | 3 | 56 | 2 | 25944446 | ||
| Pubmed | The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney. | 7.63e-06 | 3 | 56 | 2 | 26542179 | |
| Pubmed | 7.63e-06 | 3 | 56 | 2 | 33021411 | ||
| Pubmed | 7.63e-06 | 3 | 56 | 2 | 27605379 | ||
| Pubmed | 1.52e-05 | 4 | 56 | 2 | 11136725 | ||
| Pubmed | 1.52e-05 | 4 | 56 | 2 | 11747467 | ||
| Pubmed | 1.52e-05 | 4 | 56 | 2 | 23236473 | ||
| Pubmed | 1.52e-05 | 4 | 56 | 2 | 20595394 | ||
| Pubmed | 1.52e-05 | 4 | 56 | 2 | 30988100 | ||
| Pubmed | 1.52e-05 | 4 | 56 | 2 | 9820826 | ||
| Pubmed | 2.54e-05 | 5 | 56 | 2 | 22977175 | ||
| Pubmed | Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase. | 2.54e-05 | 5 | 56 | 2 | 21336257 | |
| Pubmed | 2.54e-05 | 5 | 56 | 2 | 35390160 | ||
| Pubmed | 3.80e-05 | 6 | 56 | 2 | 31924127 | ||
| Pubmed | 3.80e-05 | 6 | 56 | 2 | 20595389 | ||
| Pubmed | hCAF1, a new regulator of PRMT1-dependent arginine methylation. | 3.80e-05 | 6 | 56 | 2 | 17264152 | |
| Pubmed | CNOT7/hCAF1 is involved in ICAM-1 and IL-8 regulation by tristetraprolin. | 3.80e-05 | 6 | 56 | 2 | 25038453 | |
| Pubmed | Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits. | 5.32e-05 | 7 | 56 | 2 | 10637334 | |
| Pubmed | 9.10e-05 | 9 | 56 | 2 | 21078877 | ||
| Pubmed | 9.10e-05 | 9 | 56 | 2 | 21741365 | ||
| Pubmed | 1.66e-04 | 12 | 56 | 2 | 17452450 | ||
| Pubmed | 1.66e-04 | 12 | 56 | 2 | 31320642 | ||
| Pubmed | Human Ccr4-Not complexes contain variable deadenylase subunits. | 1.66e-04 | 12 | 56 | 2 | 19558367 | |
| Pubmed | 2.29e-04 | 14 | 56 | 2 | 20584987 | ||
| Pubmed | 2.64e-04 | 15 | 56 | 2 | 11318611 | ||
| Pubmed | GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. | 2.64e-04 | 15 | 56 | 2 | 21981923 | |
| Pubmed | EDEM3 Domains Cooperate to Perform Its Overall Cell Functioning. | 4.28e-04 | 19 | 56 | 2 | 33671632 | |
| Pubmed | RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation. | 4.75e-04 | 20 | 56 | 2 | 34887419 | |
| Pubmed | BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes. | 6.87e-04 | 24 | 56 | 2 | 27065194 | |
| Pubmed | 1.08e-03 | 30 | 56 | 2 | 11374901 | ||
| Pubmed | An inter-species protein-protein interaction network across vast evolutionary distance. | 1.08e-03 | 483 | 56 | 5 | 27107014 | |
| Pubmed | High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface. | 1.52e-03 | 307 | 56 | 4 | 37499664 | |
| Cytoband | 1q25 | 4.38e-06 | 26 | 56 | 3 | 1q25 | |
| Cytoband | 11q22.3 | 2.20e-05 | 44 | 56 | 3 | 11q22.3 | |
| Cytoband | 10q23.2 | 1.96e-04 | 17 | 56 | 2 | 10q23.2 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q22 | 3.12e-04 | 107 | 56 | 3 | chr11q22 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1q25 | 1.14e-03 | 167 | 56 | 3 | chr1q25 | |
| Cytoband | 10q22.3 | 1.28e-03 | 43 | 56 | 2 | 10q22.3 | |
| GeneFamily | Zinc fingers CCCH-type | 4.94e-05 | 35 | 37 | 3 | 73 | |
| GeneFamily | CCR4-NOT transcription complex | 2.22e-04 | 11 | 37 | 2 | 1023 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 3.14e-06 | 180 | 56 | 5 | b927e7380369da6f92ba23d96103519884b70595 | |
| ToppCell | Bronchial_Brush-Epithelial-Ciliated_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X | 2.31e-05 | 132 | 56 | 4 | 780a391924f776dc6fbe44ddcf4ae0583a1e2157 | |
| ToppCell | Bronchial_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X | 2.52e-05 | 135 | 56 | 4 | 366a417f9ef7c0d86e9f262d97bf788f478315ee | |
| ToppCell | Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 2.83e-05 | 139 | 56 | 4 | 7c02caed5b9baf233bd6fb9a453708b3e157c790 | |
| ToppCell | droplet-Fat-Mat-18m-Hematologic-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 7.09e-05 | 176 | 56 | 4 | 867936a20f73f638055c19c8d88834aa2cc657cf | |
| ToppCell | renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 7.90e-05 | 181 | 56 | 4 | b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.42e-05 | 184 | 56 | 4 | ea7a7e2bac46d4d2c31a5d576b38a032b5335062 | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.42e-05 | 184 | 56 | 4 | 2cbed6462fea2622871bb7e49b0df3d984239281 | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.42e-05 | 184 | 56 | 4 | 2b19a8c5f823e00812908b23e66bb4e563278aff | |
| ToppCell | SMG-Goblet|World / shred by cell class for bronchial biopsy | 8.96e-05 | 187 | 56 | 4 | 5178118bdec91495253c88f58fd908cf831de7ef | |
| ToppCell | PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung | 9.34e-05 | 189 | 56 | 4 | c8b8f860aaf6c73863cd79941db6b469c830ef06 | |
| ToppCell | T_cells-Effector_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis | 9.53e-05 | 190 | 56 | 4 | 13dc3a0aaa554f63eabac37726bd1f11b66fb3dd | |
| ToppCell | renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 9.73e-05 | 191 | 56 | 4 | 3e828cffa24ded19f591a7ed6c1fe88ad57fdcac | |
| ToppCell | PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung | 9.73e-05 | 191 | 56 | 4 | 60ff989fe99d243a3d52955223680cdd1f1917a4 | |
| ToppCell | PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 1.01e-04 | 193 | 56 | 4 | b38aaffbea36ef6c08ebe82675438f873c89b242 | |
| ToppCell | renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.03e-04 | 194 | 56 | 4 | 69bff17df4a760ccf081cf52ff04af02c14f448d | |
| ToppCell | renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.03e-04 | 194 | 56 | 4 | 04bfc555743f7d8821439d05ae442d15e9886c59 | |
| ToppCell | PCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung | 1.03e-04 | 194 | 56 | 4 | f95c8dc242c9aebcadfe61b1ed033349cb7e5a88 | |
| Disease | Endometrial Stromal Sarcoma | 3.28e-05 | 5 | 54 | 2 | C0206630 | |
| Disease | Clear cell sarcoma of kidney | 4.91e-05 | 6 | 54 | 2 | C0334488 | |
| Disease | cerebrospinal fluid biomarker measurement, monocyte chemotactic protein 1 measurement | 4.91e-05 | 6 | 54 | 2 | EFO_0006794, EFO_0010596 | |
| Disease | anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine | 1.79e-04 | 11 | 54 | 2 | EFO_0803358, EFO_0803362 | |
| Disease | thyroid volume | 3.88e-04 | 16 | 54 | 2 | EFO_0004865 | |
| Disease | stomach carcinoma (is_marker_for) | 8.84e-04 | 24 | 54 | 2 | DOID:5517 (is_marker_for) | |
| Disease | response to tenofovir, creatinine clearance measurement | 1.15e-03 | 112 | 54 | 3 | EFO_0007934, EFO_0009279 | |
| Disease | neuroblastoma | 1.27e-03 | 116 | 54 | 3 | EFO_0000621 | |
| Disease | response to radiation, prostate carcinoma, erectile dysfunction | 2.10e-03 | 37 | 54 | 2 | EFO_0001663, EFO_0004234, GO_0009314 | |
| Disease | heart disease (implicated_via_orthology) | 2.22e-03 | 38 | 54 | 2 | DOID:114 (implicated_via_orthology) | |
| Disease | bitter beverage consumption measurement | 2.70e-03 | 42 | 54 | 2 | EFO_0010089 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| FKDSMSYELRFFPDM | 131 | Q8WWZ7 | |
| FFREFLERMSQMYEI | 331 | Q05D32 | |
| KDGDLFMSYRSMFQD | 186 | P49902 | |
| FEKVISMEYMVYFNF | 171 | P30542 | |
| FVMKTDSDMFINVDY | 151 | Q9Y2C3 | |
| FDDMFEDMEKMFSFS | 166 | Q9UBS3 | |
| KIYEFRLMMEFSGEN | 86 | Q8TBY0 | |
| FKETFMCEFFKMFQE | 561 | Q15283 | |
| FFRAMFEVNMKERDD | 76 | Q8NAB2 | |
| SNMRMQFSFEEYEKA | 386 | Q5JU85 | |
| DRMDSFFLAEMFKYL | 456 | Q9BZQ6 | |
| SNMRFMQFRAKDSYS | 906 | Q5JUK3 | |
| FDEADRMFDMGFEYQ | 406 | Q86XP3 | |
| YFRAMFLSEMAEAKQ | 91 | Q9P2G9 | |
| NRFVREYKSMVDFMN | 271 | Q99784 | |
| DDMDSYTNVYRMFSK | 66 | Q969I3 | |
| FPTMKMFEYVRNDRD | 306 | O77932 | |
| FGEMADNFKSDYFNM | 366 | P29375 | |
| RMIFYEMAERFMEFE | 276 | Q86Y26 | |
| EKRMQFFDSMRNEYF | 116 | Q16322 | |
| RQFDHMKDMFDEYVK | 811 | Q9HAP2 | |
| MAFFKMREMFFEDHI | 236 | Q9UIV1 | |
| LCYRFMKEFTFLMEN | 431 | Q8TF40 | |
| LMEYFRNEDSNIDFM | 306 | Q8IVF7 | |
| QVFDDFIFIFFAMEM | 116 | Q9P0X4 | |
| DFYRNYDVMKDFEEM | 51 | P09669 | |
| FYMDKVLMEFVENSR | 616 | Q8WWI5 | |
| MAFFRMKELFFEDSI | 236 | Q9UFF9 | |
| RFYFNEDSDKMMIHI | 1921 | Q8TE73 | |
| SNFDRMIFYEMAEKF | 391 | Q8IVF1 | |
| MIFYEMAEKFLEFEA | 396 | Q8IVF1 | |
| SNFDRMIFYEMAEKF | 391 | A6NNL0 | |
| MIFYEMAEKFLEFEA | 396 | A6NNL0 | |
| FDRMIFYEMAEKFLE | 321 | Q5VT03 | |
| SNFDRMIFYEMAEKF | 391 | B1AL46 | |
| MIFYEMAEKFLEFEA | 396 | B1AL46 | |
| DRMIFYEMAEKFLEF | 271 | A1L443 | |
| DRMIFYEMAAKFLEF | 271 | Q5VZR2 | |
| AFAEMLRFGDRMFYK | 391 | P35610 | |
| QMKERQGLFFDMEAY | 86 | Q9BXJ8 | |
| QLEDFFDIMKYLFML | 1751 | B5MCY1 | |
| RGEVMFFKDRFYMRT | 291 | P03956 | |
| DFYSFMIMKTNFNKE | 881 | Q5K651 | |
| SEMKYFAEYLSMDAQ | 171 | Q6NSI8 | |
| METFGMKYRDAFAYV | 136 | Q8WUJ0 | |
| EERLLMYSFVNDKFM | 261 | Q5D1E8 | |
| VERMMKDVFFFLFFL | 866 | Q9NZQ8 | |
| DYMKQMTFEAQAFLE | 201 | Q9BZQ8 | |
| FEYVMFYNDIEKRMV | 121 | Q5T1C6 | |
| SSFFMEMEYKKLFAM | 376 | Q8IWV7 | |
| MSNKMFSAEYEFFPE | 1126 | P53804 | |
| MREFFILSYKMSQFC | 656 | Q8IYF3 | |
| EERLLMYSFVNDKFM | 316 | Q5HYM0 | |
| FEEFCVFYKMMSLRR | 201 | Q4KWH8 | |
| DERLLMYSFVNDKFM | 371 | Q9C0D7 | |
| EVYSMDMFHTRFKQE | 616 | P52888 | |
| LEDFFMKMFDRWTYS | 86 | O75795 | |
| NDNSSRFGKYLEMMF | 486 | Q8WXR4 | |
| YEFFRAPEKDMVSMA | 1616 | Q6PIF6 |