Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsulfonylurea receptor activity

ABCC9 ABCC8

4.34e-0521322GO:0008281
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F8 CYP4F11

4.28e-0451322GO:0052871
GeneOntologyMolecularFunctionNADPH-hemoprotein reductase activity

NDOR1 CYP2J2

4.28e-0451322GO:0003958
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F8 CYP2J2 CYP4F11

5.16e-04241323GO:0008392
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

VN1R3 OR4C11 OPN3 FPR2 TMEM63C ABCC9 OR2H1 OR2B6 RGR OR6M1 ADCYAP1R1 ZACN OR13D1 OR5AC2 CD14 OR6C4 ABCC8 OR6C75 P2RY10 CD300E

5.73e-04135313220GO:0004888
GeneOntologyMolecularFunctionATP-activated inward rectifier potassium channel activity

ABCC9 ABCC8

6.39e-0461322GO:0015272
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F8 CYP2J2 CYP4F11

7.35e-04271323GO:0008391
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F8 CYP4F11

8.91e-0471322GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F8 CYP4F11

8.91e-0471322GO:0018685
GeneOntologyMolecularFunctionlipoteichoic acid binding

LBP CD14

8.91e-0471322GO:0070891
GeneOntologyMolecularFunctionhormone receptor binding

NPPB CSHL1 UCN

1.45e-03341323GO:0051427
GeneOntologyMolecularFunctionaromatase activity

CYP4F8 CYP2J2 CYP4F11

1.58e-03351323GO:0070330
GeneOntologyMolecularFunctionpotassium channel activity

ABCC9 LRG1 TRPM5 KCNG1 ABCC8

1.62e-031281325GO:0005267
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F8 CYP4F11

1.89e-03101322GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F8 CYP4F11

1.89e-03101322GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F8 CYP4F11

1.89e-03101322GO:0102033
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC39A2 TRPC4 SLC30A8 TMEM63C ABCC9 SLC4A3 LRG1 SLC26A1 LETM1 CNNM3 ZACN TRPM5 KCNG1 ABCC8 AP4M1 SLC23A3 SLC22A31

2.01e-03118013217GO:0022857
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPC4 TMEM63C ABCC9 LRG1 ZACN TRPM5 KCNG1 ABCC8

2.04e-033431328GO:0005261
GeneOntologyMolecularFunctionhormone activity

NPPB INHA FBN1 CSHL1 UCN

2.04e-031351325GO:0005179
GeneOntologyMolecularFunctiontransporter activity

SLC39A2 TRPC4 SLC30A8 TMEM63C ABCC9 ATP10A SLC4A3 LRG1 SLC26A1 LETM1 CNNM3 ZACN TRPM5 KCNG1 ABCC8 AP4M1 SLC23A3 SLC22A31

2.08e-03128913218GO:0005215
GeneOntologyMolecularFunctionG protein-coupled receptor activity

VN1R3 OR4C11 OPN3 FPR2 OR2H1 OR2B6 RGR OR6M1 ADCYAP1R1 OR13D1 OR5AC2 OR6C4 OR6C75 P2RY10

2.16e-0388413214GO:0004930
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC39A2 TRPC4 SLC30A8 TMEM63C ABCC9 SLC4A3 LRG1 SLC26A1 LETM1 ZACN TRPM5 KCNG1 ABCC8

2.31e-0379313213GO:0015075
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TMEM63C ABCC9 ZACN TRPM5 ABCC8

2.39e-031401325GO:0099094
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, heme protein as acceptor

NDOR1 CYP2J2

2.74e-03121322GO:0016653
GeneOntologyCellularComponentpotassium ion-transporting ATPase complex

ABCC9 ABCC8

1.22e-0431342GO:0031004
GeneOntologyCellularComponentinward rectifying potassium channel

ABCC9 ABCC8

2.43e-0441342GO:0008282
GeneOntologyCellularComponentAP-4 adaptor complex

TEPSIN AP4M1

4.03e-0451342GO:0030124
DomainARM-type_fold

USP34 STK36 DNAJC13 DOCK8 HUWE1 WDFY4 PIK3R4 URB1 THADA PPP2R5E PIK3C2A IFRD2 ULK4 ARMC8

1.41e-0733913314IPR016024
DomainARM-like

STK36 DNAJC13 DOCK8 HUWE1 WDFY4 PIK3R4 PPP2R5E IFRD2 ULK4 ARMC8

2.39e-0527013310IPR011989
DomainSulphorea_rcpt

ABCC9 ABCC8

5.03e-0521332IPR000388
DomainLeu-rich_rpt

VASN LGI4 LRG1 TSKU IGSF10 CD14 TONSL FLRT3 LRRC41

1.42e-042711339IPR001611
Domain-

STK36 DNAJC13 WDFY4 PIK3R4 PPP2R5E IFRD2 ULK4 ARMC8

1.93e-0422213381.25.10.10
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

RNF213 THADA NLRP10 PPP2R5E FBXO6 DOP1B ARMC8 SOS1

6.32e-07183135823956138
Pubmed

Promoter DNA methylation regulates murine SUR1 (Abcc8) and SUR2 (Abcc9) expression in HL-1 cardiomyocytes.

ABCC9 ABCC8

1.50e-052135222844491
Pubmed

Lipopolysaccharide-binding protein and CD14 are increased in the bronchoalveolar lavage fluid of smokers.

LBP CD14

1.50e-052135219010986
Pubmed

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity.

ABCC9 ABCC8

1.50e-052135226181369
Pubmed

Evidence of a trimolecular complex involving LPS, LPS binding protein and soluble CD14 as an effector of LPS response.

LBP CD14

1.50e-052135212417309
Pubmed

LBP and sCD14 patterns in total hip replacement surgery performed during combined spinal/epidural anaesthesia.

LBP CD14

1.50e-052135221722015
Pubmed

Lipopolysaccharide binding protein and sCD14 are not produced as acute phase proteins in cardiac surgery.

LBP CD14

1.50e-052135218288274
Pubmed

Low potency of Chlamydophila LPS to activate human mononuclear cells due to its reduced affinities for CD14 and LPS-binding protein.

LBP CD14

1.50e-052135218056918
Pubmed

Structure and function of lipopolysaccharide binding protein.

LBP CD14

1.50e-05213522402637
Pubmed

Postprandial Endotoxin Transporters LBP and sCD14 Differ in Obese vs. Overweight and Normal Weight Men during Fat-Rich Meal Digestion.

LBP CD14

1.50e-052135232570947
Pubmed

Lipopolysaccharide-binding protein- and CD14-dependent activation of mitogen-activated protein kinase p38 by lipopolysaccharide in human neutrophils is associated with priming of respiratory burst.

LBP CD14

1.50e-052135212117913
Pubmed

LBP and CD14 polymorphisms correlate with increased colorectal carcinoma risk in Han Chinese.

LBP CD14

1.50e-052135221633598
Pubmed

Identification of CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis using proteomics of serum extracellular vesicles.

LBP CD14

1.50e-052135235294531
Pubmed

Complex consequences of Cantu syndrome SUR2 variant R1154Q in genetically modified mice.

ABCC9 ABCC8

1.50e-052135233529173
Pubmed

ULK4 and Fused/STK36 interact to mediate assembly of a motile flagellum.

STK36 ULK4

1.50e-052135236989043
Pubmed

Distribution of CD14+ and CD68+ macrophages in the placental bed and basal plate of women with preeclampsia and preterm labor.

CD14 CD68

1.50e-052135217052752
Pubmed

Soluble CD14 subtype presepsin (sCD14-ST) and lipopolysaccharide binding protein (LBP) in neonatal sepsis: new clinical and analytical perspectives for two old biomarkers.

LBP CD14

1.50e-052135221740312
Pubmed

LPS signaling enhances hepatic fibrogenesis caused by experimental cholestasis in mice.

LBP CD14

1.50e-052135216439470
Pubmed

[Clinical study of serum lipopolysaccharide-binding protein and soluble CD14 in severe sepsis patients].

LBP CD14

1.50e-052135216512634
Pubmed

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.

DOCK8 NLRP10

1.50e-052135225713392
Pubmed

LPS-binding proteins and receptors.

LBP CD14

1.50e-05213529665271
Pubmed

Gene expression of a novel cytochrome P450 of the CYP4F subfamily in human seminal vesicles.

CYP4F8 CYP2J2

1.50e-052135210405341
Pubmed

The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.

TEPSIN AP4M1 FHIP1A

1.59e-0513135332073997
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

TPP2 USP34 UBR1 ZZEF1 USP16 PIK3R4 LRRC41

2.03e-05212135733853758
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6C USP34 STK36 NDOR1 PCNX3 DYRK1A HUWE1 ZZEF1 TAOK2 URB1 THADA KCNG1 IFRD2 SNX8 ULK4

2.72e-0511051351535748872
Pubmed

Butyrophilin 2a2 (Btn2a2) expression on thymic epithelial cells promotes central T cell tolerance and prevents autoimmune disease.

BTN2A1 BTN2A2

4.48e-053135237356345
Pubmed

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.

LBP CD14

4.48e-053135212370383
Pubmed

RANKL-Induced Btn2a2 - A T Cell Immunomodulatory Molecule - During Osteoclast Differentiation Fine-Tunes Bone Resorption.

BTN2A1 BTN2A2

4.48e-053135234421818
Pubmed

Lipopolysaccharide (LPS)-binding protein inhibits responses to cell-bound LPS.

LBP CD14

4.48e-053135212754215
Pubmed

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane.

LBP CD14

4.48e-053135224380872
Pubmed

Interaction of SP-A (surfactant protein A) with bacterial rough lipopolysaccharide (Re-LPS), and effects of SP-A on the binding of Re-LPS to CD14 and LPS-binding protein.

LBP CD14

4.48e-053135215932345
Pubmed

Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells.

SLC30A8 ABCC8

4.48e-053135223382449
Pubmed

Roles of endotoxin-related signaling molecules in the progression of acute necrotizing pancreatitis in mice.

LBP CD14

4.48e-053135216163057
Pubmed

Functional roles of KATP channel subunits in metabolic inhibition.

ABCC9 ABCC8

4.48e-053135223624089
Pubmed

The effect of the accessory proteins, soluble CD14 and lipopolysaccharide-binding protein on Toll-like receptor 4 activity in human monocytes and adipocytes.

LBP CD14

4.48e-053135226880233
Pubmed

Recognition of gram-negative bacteria and endotoxin by the innate immune system.

LBP CD14

4.48e-053135210047547
Pubmed

Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles.

TEPSIN DENND4C

4.48e-053135222472443
Pubmed

A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels.

ABCC9 ABCC8

4.48e-05313528630239
Pubmed

LPS-dependent interaction of Mac-2-binding protein with immobilized CD14.

LBP CD14

4.48e-05313527583357
Pubmed

Btn2a2 Regulates ILC2-T Cell Cross Talk in Type 2 Immune Responses.

BTN2A1 BTN2A2

8.93e-054135235145516
Pubmed

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.

NDOR1 DYRK1A

8.93e-054135237310920
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F8 CYP4F11

8.93e-054135222665481
Pubmed

Assembly limits the pharmacological complexity of ATP-sensitive potassium channels.

ABCC9 ABCC8

8.93e-054135211825905
Pubmed

Human lipopolysaccharide-binding protein (LBP) and CD14 independently deliver triacylated lipoproteins to Toll-like receptor 1 (TLR1) and TLR2 and enhance formation of the ternary signaling complex.

LBP CD14

8.93e-054135223430250
Pubmed

Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes.

BTN2A1 BTN2A2

8.93e-054135223589618
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F8 CYP4F11

8.93e-054135211185557
Pubmed

Circulating pathogen-associated molecular pattern - binding proteins and High Mobility Group Box protein 1 in nascent metabolic syndrome: implications for cellular Toll-like receptor activity.

LBP CD14

8.93e-054135225063948
Pubmed

Insights into human Lck SH3 domain binding specificity: different binding modes of artificial and native ligands.

FAM174A SOS1

8.93e-054135216274251
Pubmed

Serum lipopolysaccharide-binding protein and soluble CD14 are markers of disease activity in patients with Crohn's disease.

LBP CD14

8.93e-054135220865702
Pubmed

Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders.

PIGL PIGO

8.93e-054135228327575
Pubmed

A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.

ABCC9 ABCC8

8.93e-05413528798681
Pubmed

Granular cell tumor: immunohistochemical assessment of inhibin-alpha, protein gene product 9.5, S100 protein, CD68, and Ki-67 proliferative index with clinical correlation.

INHA CD68

8.93e-054135215214825
Pubmed

Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium.

ABCC9 ABCC8

8.93e-054135212356945
Pubmed

Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart.

ABCC9 ABCC8

8.93e-054135216085792
Pubmed

Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons.

ABCC9 ABCC8

8.93e-054135210022826
Pubmed

Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.

ABCC9 ABCC8

8.93e-054135228842488
Pubmed

A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children.

IL12A CD14

8.93e-054135215356557
Pubmed

Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes.

BTN2A1 BTN2A2

8.93e-054135226809444
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F8 CYP4F11

1.48e-045135222969154
Pubmed

Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain.

ABCC9 PIK3C2A

1.48e-04513529514948
Pubmed

Lipoteichoic acid-induced lung inflammation depends on TLR2 and the concerted action of TLR4 and the platelet-activating factor receptor.

LBP CD14

1.48e-045135218292574
Pubmed

An Anti-Inflammatory Role for NLRP10 in Murine Cutaneous Leishmaniasis.

DOCK8 NLRP10

1.48e-045135228931602
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F8 CYP4F11

1.48e-045135221466787
Pubmed

Effects of CD14, TLR2, TLR4, LPB, and IL-6 gene polymorphisms on Chlamydia pneumoniae growth in human macrophages in vitro.

LBP CD14

1.48e-045135219522765
Pubmed

Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses.

LBP CD14

1.48e-045135215294986
Pubmed

Expression of opsin genes early in ocular development of humans and mice.

OPN3 RGR

1.48e-045135212573668
Pubmed

Ankyrin-B regulates Kir6.2 membrane expression and function in heart.

ABCC9 ABCC8

2.22e-046135220610380
Pubmed

Pathway genetic load allows simultaneous evaluation of multiple genetic associations.

LBP CD14

2.22e-046135220381257
Pubmed

Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved.

LBP CD14

2.22e-046135212594207
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F8 CYP4F11

2.22e-04613529068972
Pubmed

BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.

BTN2A1 BTN2A2

2.22e-046135220208008
Pubmed

Polymorphisms within inflammatory genes and colorectal cancer.

IL12A CD14

3.10e-047135217062130
Pubmed

The cluster of BTN genes in the extended major histocompatibility complex.

BTN2A1 BTN2A2

3.10e-047135211170752
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F8 CYP4F11

3.10e-047135222160543
Pubmed

Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.

UBR1 HUWE1 ZZEF1 PGRMC1

3.29e-0484135431616248
Pubmed

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.

RNF213 HUWE1 FBXL18 FBXO6

3.45e-0485135419028597
Pubmed

Transient expression of MIDC-8 in the normal mouse brain.

CD14 CD68

4.12e-048135215755524
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

DCAKD TPP2 USP34 RNF213 UFL1 HUWE1 PGRMC1 LETM1 URB1 THADA FBXO6 PIK3C2A ALDH18A1 DDX60L ARMC8

4.91e-0414401351530833792
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 SORBS2 DYRK1A HUWE1 USP16 SLC4A3 PIK3R4 FBN1 PPP2R5E DENND6B DOP1B ARMC8 VCPIP1 SOS1

4.91e-0412851351435914814
Pubmed

Discovering human diabetes-risk gene function with genetics and physiological assays.

SLC30A8 ABCC8

5.29e-049135230242153
Pubmed

Gene polymorphisms of Toll-like and related recognition receptors in relation to the vaginal carriage of Gardnerella vaginalis and Atopobium vaginae.

LBP CD14

5.29e-049135219200604
Pubmed

Murine protein kinase CK2 alpha': cDNA and genomic cloning and chromosomal mapping.

DYRK1A SNTB2

5.29e-04913529503019
Pubmed

Genetic variants in immunoregulatory genes and risk for childhood lymphomas.

IL12A CD14

5.29e-049135219508433
Pubmed

Defining the membrane proteome of NK cells.

DCAKD DNAJC13 DOCK8 RNF213 MCM4 NOL9 HUWE1 PGRMC1 PIK3R4 CNNM3 PIK3C2A PIGO LRRC41

6.44e-0411681351319946888
Pubmed

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

MCM4 TONSL

6.59e-0410135221055985
Pubmed

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

USP34 HUWE1

6.59e-0410135217478428
Pubmed

Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3.

TPP2 INHA

6.59e-041013521682057
Pubmed

Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.

LBP CD14

6.59e-0410135226431947
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RNF213 HUWE1 WDFY4 EPG5

6.62e-04101135410997877
Pubmed

Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.

LBP GDF10 CD14

6.74e-0444135321308778
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP4F8 CYP2J2 CYP4F11

6.74e-0444135312745259
Pubmed

Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.

DYRK1A DOP1B

8.04e-041113529503011
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

DCAKD USP34 P4HA2 VASN RNF213 ZZEF1 BTN2A1 TSKU IGSF10 CNNM3 THADA FBN1 PIGO

8.32e-0412011351335696571
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UBR1 DNAJC13 SORBS2 MCM4 UFL1 HUWE1 USP16 PGRMC1 VCPIP1 SOS1

9.14e-047741351015302935
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

UBR1 NOL9 ZZEF1 LETM1 IFRD2 TONSL DOP1B ARMC8

9.41e-04515135831617661
Pubmed

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.

FPR2 TRPM5

9.62e-0412135232294408
Pubmed

Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.

RGR FBN1

9.62e-0412135226405179
Pubmed

Congenital hydrocephalus in genetically engineered mice.

STK36 ULK4

9.62e-0412135221746835
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

UBR1 ORC3 NOL9 ZZEF1 LETM1 PIK3R4 CDC40 TONSL LRRC41

1.02e-03650135938777146
Pubmed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.

FPR2 ZZEF1 LRG1 PRG3 CD14

1.08e-03198135527480124
Cytoband3q22.1

DNAJC13 PIK3R4 NPHP3

2.62e-044213533q22.1
CytobandEnsembl 112 genes in cytogenetic band chr2q35

STK36 INHA SLC4A3 SLC23A3

5.92e-041291354chr2q35
CytobandEnsembl 112 genes in cytogenetic band chr3q22

DNAJC13 PIK3R4 NPHP3 ARMC8

7.02e-041351354chr3q22
GeneFamilyOpsin receptors

OPN3 RGR

1.28e-0311892215
GeneFamilyATP binding cassette subfamily C

ABCC9 ABCC8

1.80e-0313892807
GeneFamilyOlfactory receptors, family 6

OR6M1 OR6C4 OR6C75

2.02e-0351893153
GeneFamilyButyrophilins|V-set domain containing|C2-set domain containing

BTN2A1 BTN2A2

2.41e-0315892458
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

INHA VASN WDFY4 SLC4A3 IGSF10 SERPINF2 FHIP1A DNASE1L3

4.47e-081681348968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2-Th.Adora2a-Th_(Striatum,_Th+_SPN)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC30A8 STRIT1 SPINK14 LOXHD1 SLC23A3

7.35e-07561345e6b2f6ff08887ae8335c44d7fff118c371768809
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2-Th.Adora2a-Th_(Striatum,_Th+_SPN)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC30A8 STRIT1 SPINK14 LOXHD1 SLC23A3

7.35e-075613457a1f39e2ebe70d757847e4fb02c39313b1ea5a2d
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

INHA VASN WDFY4 SLC4A3 IGSF10 FHIP1A DNASE1L3

7.56e-071671347bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC9 CPM TONSL ULBP1 LRRC41 RAPGEFL1 ARMC8

1.20e-061791347dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCellmyeloid-pDC|World / Lineage and Cell class

OPN3 WDFY4 SLC4A3 CD68 SERPINF2 FHIP1A DNASE1L3

1.79e-06190134788c42779ce2f817d28e672d83f3f1158581edf73
ToppCellCOVID-19_Moderate-pDC|COVID-19_Moderate / disease group, cell group and cell class

OPN3 WDFY4 SLC4A3 CD68 SERPINF2 FHIP1A DNASE1L3

1.85e-0619113479d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P4HA2 VASN LBP TSKU IGSF10 FBN1 SNTB2

1.99e-061931347160691b671710be10220803d788c2c961c236af1
ToppCellmild-pDC|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

OPN3 WDFY4 SLC4A3 IGSF10 SERPINF2 FHIP1A DNASE1L3

2.28e-06197134715230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCellsevere-pDC|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

INHA OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.35e-06198134722da4a29b9ff8b94d98bc69b4632a2a58d5dd9e6
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FPR2 CD14 DISP3 CD68 AP4M1 CD300E

6.77e-061521346931c10245cde9b3290224cc1da46b2bf300b9ac2
ToppCelldroplet-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR2 LBP LRG1 CD14 CD68 CD300E

8.45e-061581346e1a8dba5a88bc3ce112829c5ecb112cbbee5b078
ToppCelldroplet-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR2 LBP LRG1 CD14 CD68 CD300E

8.45e-06158134672e4f8ae137a7dddee0dc6236532e0711065e6af
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3 SLC23A3

1.28e-05170134659cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK8 RNF213 WDFY4 ATP10A DENND4C CD68

1.37e-051721346c8ea80042faf923b08ff03d73100533d521d73ef
ToppCellmild_COVID-19-pDC|World / disease group, cell group and cell class (v2)

CYP2J2 OPN3 SLC4A3 SERPINF2 FHIP1A DNASE1L3

1.37e-051721346dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDFY4 CD14 P2RY10 CD68 FLRT3 DNASE1L3

1.37e-051721346eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCell10x5'-blood-Myeloid_Dendritic|blood / Manually curated celltypes from each tissue

WDFY4 SLC4A3 OR6C75 SERPINF2 FHIP1A DNASE1L3

1.51e-0517513461c48eec300d5a6d4a810947b995af3b8c0a5a601
ToppCellmild_COVID-19-pDC|mild_COVID-19 / disease group, cell group and cell class (v2)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

1.51e-051751346b87f279a7519710146c49d6acccb0adedc195965
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

WDFY4 SLC4A3 UCN SERPINF2 FHIP1A DNASE1L3

1.83e-0518113465a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK8 WDFY4 CD14 MSLNL CD68 CD300E

1.95e-05183134624679153b654c148dbd572e9013c0a6e58718ada
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DOCK8 RNF213 MCM4 HUWE1 URB1 DOP1B

2.07e-051851346a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellPBMC-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.13e-05186134631df1eafa3010bc1be6fc4d4689f1393d69b6b13
ToppCellPBMC-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.13e-051861346eaa431ccd4cdd36fe06a44987603ec9979025aa8
ToppCellMultiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

OPN3 WDFY4 SLC4A3 CD68 SERPINF2 DNASE1L3

2.13e-051861346330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCellPBMC-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.13e-051861346b95be984e308d4f9061274a35995ec558d434e74
ToppCellPBMC-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.13e-0518613468f7949740286f64e034d1eb533ebc2c6f71ae966
ToppCellPBMC-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.13e-05186134695c7318e521fb6aa02e244b1e81e6b2a62107756
ToppCellPBMC-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.13e-051861346b70cd94c651b56dcf2e55554533a5f1130845390
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DOCK8 RNF213 MCM4 HUWE1 URB1 DOP1B

2.13e-0518613468571956890fc9894d766ba294a28e376b4aba428
ToppCellCOVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease group, lineage and cell class

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.13e-0518613463db5ed69d49e5d79f990aca0295ddce4c297a05c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 TRPC4 ABCC9 CPM LGI4 ATP10A

2.20e-051871346ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 TRPC4 ABCC9 CPM LGI4 ATP10A

2.20e-051871346530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellPBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.26e-05188134689411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCellPBMC-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.26e-051881346de6a270b6e4fe09c39a52c296632d86ada98465b
ToppCellPBMC-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.26e-051881346879054b780378ae05be68e597c77c931bf0ade03
ToppCellPBMC-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.33e-051891346209cae68d78c8f72479b169e27c3ff7e143adece
ToppCellPBMC-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.33e-051891346a9ad1fb12304541f909dd0eeac9b9eb28c31fd41
ToppCellCOVID-19_Mild-Myeloid-pDC|COVID-19_Mild / Disease group, lineage and cell class

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.33e-051891346c6cfd6aa21c19f2c62d80218bbc924e14e82aada
ToppCellControl-Myeloid-pDC|Control / Disease group, lineage and cell class

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.33e-05189134646770b99da42f11f10cfc67cea8562342d60b867
ToppCellPBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.33e-05189134698ca646231fbd5f29827c2dd31ac4503026bad7d
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-051901346adffa93635da10251f28b2089fd96b189775c8b4
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-0519013469a91bf1ea105029e6412d0d9060bca325299ce26
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-05190134639c8ddc2639bf3e986dae11fbae61a735614b604
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-0519013462c1c079fd411c03bc3f383aa927eea9446716960
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-051901346dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-0519013466892c603037b61ef88d6ca01b7592dc0d347d63b
ToppCellPBMC-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-051901346a95aea3aa707fc4574810706341a5f32b3d00209
ToppCellPBMC-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.40e-05190134618dfa84c62dcf081ce9958a71e76a394ec0968e4
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.47e-05191134693adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC9 SLC4A3 ADCYAP1R1 TSKU THADA FBN1

2.47e-051911346b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBR1 RNF213 MCM4 HUWE1 URB1 DOP1B

2.47e-0519113469454f642c3621370fa23640b631301346b300950
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FPR2 CD14 CD68 SERPINF2 CD300E DNASE1L3

2.47e-0519113461e668d67bc254ea15518e2c7a029a61087609b7a
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P4HA2 ABCC9 LGI4 GDF10 IGSF10 FBN1

2.55e-051921346c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INHA VASN GDF10 ADCYAP1R1 IGSF10 FBN1

2.62e-0519313469d0b966d13cbce97beb43de6dc77f006c363a181
ToppCellcontrol-pDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.62e-05193134630a6559c9a9e8941861cb259b4836acccc427e68
ToppCellmild-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

OPN3 WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

2.94e-0519713460cb00daa6943f7a7fb34a8fdf51188646af65686
ToppCellsevere-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

INHA OPN3 WDFY4 SLC4A3 FHIP1A DNASE1L3

3.03e-0519813463c4820a8391088682fb3e47b914f872533bae227
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK8 OPN3 FPR2 ATP10A CD68 DDX60L

3.11e-051991346fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cacng4_(Non-anterior_nuclei)|Thalamus / BrainAtlas - Mouse McCarroll V32

FPR2 NLRP10 LOXHD1 CD300E

8.17e-057613444afc8d0e79870c635a89dd8e7ca91ebfe482b4ab
ToppCellPBMC-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

IL12A P4HA2 VASN NPHP3 RAPGEFL1

9.99e-051531345db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCellfacs-Pancreas-Exocrine-24m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12A NLRP10 P2RY10 CD68 ULBP1

1.06e-0415513456ade33c274d35ae5531956f70526005d1d5e277b
ToppCellfacs-Pancreas-Exocrine-24m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12A NLRP10 P2RY10 CD68 ULBP1

1.06e-041551345c465a22abc2b9705b6b0fc4753980f790ab8ec5e
ToppCellfacs-Pancreas-Exocrine-24m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12A NLRP10 P2RY10 CD68 ULBP1

1.06e-0415513450dec58d76e3f8cff9d62eaa4adb21a1dc7fd7487
ToppCell356C-Myeloid-Dendritic-pDC|356C / Donor, Lineage, Cell class and subclass (all cells)

OPN3 SLC4A3 THADA UCN DNASE1L3

1.09e-041561345d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPPB FPR2 LRG1 PRG3 ABCC8

1.13e-0415713459021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPPB FPR2 LRG1 PRG3 ABCC8

1.13e-041571345c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC39A2 FPR2 WDFY4 ATP10A EPG5

1.16e-0415813456811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRG1 LOXHD1 CD14 CD68 CD300E

1.20e-041591345fb9a45c1d596226128ce4f1adaebb066766e590a
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 INHA FPR2 CD14 CD300E

1.23e-041601345984990be02642a562f0c60ea99c01f005e7c02c2
ToppCellfacs-MAT-Fat-18m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR2 LRG1 CD14 CD68 CD300E

1.23e-041601345bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSKU KCNG1 TREH SERPINF2 SLC23A3

1.31e-0416213456972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCelldroplet-Spleen-nan-24m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR2 LRG1 CD14 CD68 CD300E

1.38e-0416413454d8233f69ea89d4104caa56bdd0c23c27cabe9b3
ToppCellPND01-03-samps-Myeloid-Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SLC39A2 FPR2 WDFY4 ATP10A CD68

1.38e-04164134549733a9d3d95f05056b5b01916060ff20a8de3cf
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK8 OPN3 WDFY4 P2RY10 DNASE1L3

1.42e-041651345d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TPP2 DOCK8 PIK3R4 NLRP10 C2orf49

1.42e-0416513451d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCellInfluenza_Severe-pDC|World / Disease group and Cell class

OPN3 SLC4A3 SERPINF2 FHIP1A DNASE1L3

1.46e-041661345bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FPR2 LRG1 CD14 DENND6B CD300E

1.51e-0416713451cd9e2af85c6c5b9e1d88991c87ac6980b387243
ToppCelldroplet-Lung-LUNG-1m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

URB1 NLRP10 ULBP1 FLRT3 DNASE1L3

1.51e-041671345e30e7ac8ea4399dc3c1d94fc6b857afc80a7a671
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMPRSS9 CYP4F8 SORBS2 LGI4 OR6C75

1.51e-04167134517c653b46507c8bb85da95836ae72a6015336142
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

WDFY4 SLC4A3 SERPINF2 FHIP1A DNASE1L3

1.55e-041681345dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSKU KCNG1 TREH SERPINF2 SLC23A3

1.55e-04168134535ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBXO6 CD14 ABCC8 CD68 CD300E

1.59e-041691345c3d410a5e98000ba872141b62e17ef4ed3d1a8eb
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 NLRP10 ALDH18A1 SERPINF2 DNASE1L3

1.59e-04169134546f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCellsevere_influenza-pDC|World / disease group, cell group and cell class (v2)

OPN3 SLC4A3 SERPINF2 FHIP1A DNASE1L3

1.64e-041701345b9c08af83241666bbdbed9109cadcd088c0f647d
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Monocytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FPR2 LOXHD1 CD14 CD300E SLC22A31

1.64e-0417013451c3c03821c90d41de92fef3278f71093a7fd709c
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VASN LBP GDF10 KRTDAP ULK4

1.64e-041701345d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellfacs-Spleen-nan-24m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12A SLC30A8 WDFY4 ABCC8 SNX8

1.73e-0417213450c6332a806ac75fffae6080f61965555c7f687f4
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WDFY4 P2RY10 SERPINF2 DNASE1L3 SLC23A3

1.82e-041741345991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

WDFY4 P2RY10 SERPINF2 DNASE1L3 SLC23A3

1.82e-041741345c8cec89369cf3896c5626e447051e76a142cb6df
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

RNF213 ATP10A NPHP3 P2RY10 DDX60L

1.87e-041751345ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

RNF213 ATP10A NPHP3 P2RY10 DDX60L

1.87e-041751345ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FPR2 CPM ULK4 FHIP1A RAPGEFL1

1.87e-04175134531f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OPN3 WDFY4 SLC4A3 FHIP1A DNASE1L3

1.87e-04175134597fe431f224b592b3076632d101e19136c138dcc
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

OPN3 ATP10A PIK3R4 IGSF10 DNASE1L3

1.87e-04175134529fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

P4HA2 VASN GDF10 SLC4A3 KCNG1

1.92e-041761345852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

P4HA2 ABCC9 TMEM107 GDF10 FBN1

1.92e-04176134508f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

P4HA2 VASN GDF10 SLC4A3 KCNG1

1.92e-041761345d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 TRPC4 ABCC9 CPM ATP10A

1.97e-041771345a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 WDFY4 P2RY10 CD68 DNASE1L3

1.97e-0417713453cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
DrugApigenin [520-36-5]; Up 200; 14.8uM; PC3; HT_HG-U133A

NPPB CYP4F8 TRPC4 HUWE1 TAOK2 ARSD UCN PIGO RAPGEFL1

2.34e-0619613394578_UP
Diseaseascending aortic diameter

ABCC9 FBN1 ABCC8 CD68 ULK4 HYDIN

3.77e-051401306EFO_0021787
Diseasehydrocephalus (implicated_via_orthology)

STK36 ULK4 HYDIN

7.69e-05191303DOID:10908 (implicated_via_orthology)
Diseasehypertension (is_implicated_in)

NPPB CYP2J2 NPHP3 CD14 ABCC8

2.03e-041211305DOID:10763 (is_implicated_in)
DiseaseHyperphosphatasia with Mental Retardation

PIGL PIGO

3.99e-0471302C1855923
Diseaseproteoglycan 3 measurement

USP34 PRG3

5.30e-0481302EFO_0802970
Diseaseobstructive jaundice (biomarker_via_orthology)

LBP CD14

8.47e-04101302DOID:13603 (biomarker_via_orthology)
Diseaserenal hypertension (biomarker_via_orthology)

NPPB CYP2J2

8.47e-04101302DOID:1073 (biomarker_via_orthology)
DiseaseTachycardia, Ventricular

NPPB ABCC9

1.03e-03111302C0042514
DiseaseShortened QT interval

ABCC9 SLC4A3

1.03e-03111302C0151879
Diseaseascorbic acid 2-sulfate measurement

TAOK2 SLC23A3

1.46e-03131302EFO_0800169
Diseaseascorbic acid 3-sulfate measurement

ARSD SLC23A3

1.69e-03141302EFO_0800173
DiseaseDown syndrome (implicated_via_orthology)

DYRK1A DOP1B

1.95e-03151302DOID:14250 (implicated_via_orthology)
DiseaseCardiomyopathies

NPPB ABCC9 EPG5 SOS1

2.66e-031301304C0878544
DiseaseMeckel syndrome type 1

TMEM107 NPHP3

2.81e-03181302C3714506
DiseaseHeadache

RNF213 BTN2A2 SOS1

2.86e-03641303HP_0002315
Diseasehypertension (biomarker_via_orthology)

NPPB CYP4F8 ABCC9 FBN1 CYP4F11

3.39e-032271305DOID:10763 (biomarker_via_orthology)
Diseasealpha-tocopherol measurement

DYRK1A SOS1

3.47e-03201302EFO_0007898
Diseasepulse pressure measurement, alcohol drinking

NPPB FBN1 ULK4

3.69e-03701303EFO_0004329, EFO_0005763
Diseaseperiodontitis (biomarker_via_orthology)

LBP CD14

3.83e-03211302DOID:824 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
VSLTLRAILPHAGLL

nan

181

Q6ZRM9
KVLIPLHTVRSLSLF

PPP2R5E

266

Q16537
LLHPELLSQEFLLLT

C2orf49

16

Q9BVC5
PLSDRTRLLESIHLA

EPG5

1781

Q9HCE0
PHVASLSFRSLLELR

SLC4A3

361

P48751
LFLSLLHVHIPLVTT

ARSD

296

P51689
FTTHILLLLPVLLSI

DISP3

1201

Q9P2K9
QPHVSRTLFLLLLLA

LRG1

16

P02750
VHPRTLLLGTVAFLL

CYP2J2

16

P51589
LILSPLSVALALSHL

SERPINF2

106

P08697
GFRLSSPHFLLVVLL

CD300E

166

Q496F6
LRLLFLSRNHLSTIP

FLRT3

156

Q9NZU0
LLHISLLLIESRLEP

CSHL1

106

Q14406
SLFHILVTPLFLLST

ABCC9

576

O60706
PLHTLRSRLSIILQD

ABCC9

1381

O60706
LLDHLRLLAPSTSLL

AP5S1

146

Q9NUS5
TALLFLATPELSIIH

DYRK1A

271

Q13627
LRRHLLELTQSFIIP

DENND6B

416

Q8NEG7
LLELFTHVPARQLLL

FBXO6

21

Q9NRD1
GSTFSHLLVPILLLI

STRIT1

6

P0DN84
LPHLGRLTFELLHTL

ATP10A

726

O60312
PFSLLELLSRLATLL

AP4M1

76

O00189
PVFSLLSFILIHLVL

SPINK14

6

Q6IE38
LRHRQTIDFPLLTSL

KIAA0895L

401

Q68EN5
SIILSPAVHLDLLSL

CD68

281

P34810
LPHTLLSRFDLIFLL

MCM4

636

P33991
LLLLIDLIRLLSPSH

NOL9

416

Q5SY16
LVSELFHLIPLTLIL

OR2B6

201

P58173
RALPSILLALLLTST

LBP

6

P18428
ESLLHLLIRRHTLPT

NLRP10

271

Q86W26
ERLIHSLPTSLERAL

FPR2

311

P25090
FRVLLLRISPQHLTS

DOP1B

2076

Q9Y3R5
HLLAPVFRTLSILTN

ERVMER34-1

26

Q9H9K5
ELHSTLIRLLNELLP

KIAA2026

806

Q5HYC2
LHQEIPTSLLILSRA

LETM1

406

O95202
IFHIELAVLLSPLSR

LOXHD1

346

Q8IVV2
DFPELLSLRTALILH

DDX60L

96

Q5H9U9
LPLFLLLLRDVAGSH

GDF10

21

P55107
ILRLGSLHAITIFSL

TMEM63C

676

Q9P1W3
ILSNTPSLLALRHVL

PCNX3

1691

Q9H6A9
LPAVVLLSLLVLHSA

KRTDAP

6

P60985
ISQLPLESVLHLTLF

PIK3C2A

751

O00443
LLHEIFTSPLNLLLL

PGRMC1

21

O00264
FLRSPLTLIDLVAIL

KCNG1

296

Q9UIX4
LRTNLDTLLQHLLPT

MSLNL

336

Q96KJ4
LSFLHRLPILLKGTS

TEPSIN

11

Q96N21
APSRALLLLLFLHLA

NPPB

6

P16860
SLLLVATLVLLDHLS

IL12A

6

P29459
LIHSTAQIILALRLP

OR4C11

151

Q6IEV9
TLIAFPALLEIRISL

OR6M1

11

Q8NGM8
LTIITLTLLDPHLQT

OR6C4

41

Q8NGE1
LQLDSILSSLEPLHR

HUWE1

846

Q7Z6Z7
IASSLLTHPSRLQIL

NDOR1

386

Q9UHB4
LARSTLLLIPLFGIH

ADCYAP1R1

351

P41586
ETLLIHRDLLRTPLF

ALDH18A1

616

P54886
ALELTRRLLSLDPSH

P4HA2

226

O15460
LHPLVHVSLLLRLTF

OR5AC2

156

Q9NZP5
LLPFLLLGTVSALHL

PRG3

6

Q9Y2Y8
RLRTPTHLLLVNISL

OPN3

71

Q9H1Y3
ELRTPCHLLVLSLAL

RGR

46

P47804
RHVLLLGFTPLSESI

FAXDC2

311

Q96IV6
TLGLLRNLLSTRPHI

ARMC8

531

Q8IUR7
CLLLLLLPLVHVSAT

CD14

6

P08571
LIFSLLIPFIHREGS

FHIP1A

196

Q05DH4
LILERSHLLSETPQL

IGSF10

386

Q6WRI0
DPLLREHLSVLSRTF

HYDIN

371

Q4G0P3
APLLLLLLSIHSALA

DNASE1L3

6

Q13609
NSSRLEPLVLFLHLV

DOCK8

781

Q8NF50
PFIIAALATLHLLFL

MT-CYB

186

P00156
TKPSLFLFLVSLLHI

CPM

426

P14384
LLHTELERSLEYLPL

DCAKD

191

Q8WVC6
RILELLPALTTLTNH

FBN1

2776

P35555
VLALTLLHFRILPTH

CYP4F11

481

Q9HBI6
VLALTLLRFRILPDH

CYP4F8

481

P98187
FVLLESKILLHSLRP

DENND4C

411

Q5VZ89
ALHFSRPASLLLLLL

BTN2A1

6

Q7KYR7
ALLHSLPSSRQLVLE

DNAJC13

1821

O75165
ELFHSLQPLLVSVLS

IFRD2

221

Q12894
LSLLTHPVLVLLLRC

INHA

186

P05111
LVLESLLHLIYLTTP

HELQ

861

Q8TDG4
ELLALHLSVIPTDLL

HPS1

666

Q92902
ALHFSLPASLLLLLL

BTN2A2

6

Q8WVV5
LAASFPTLLVLRLLH

SLC22A31

176

A6NKX4
LSVADLAHVLSLPLR

P2RY10

76

O00398
LIIITLTLSDPHLQT

OR6C75

41

A6NL08
RLLPHAVSSLLCIEL

ORC3

261

Q9UBD5
SHLLASVLLLLLLPE

FAM174A

11

Q8TBP5
LLIIITILDSRLHTP

OR13D1

76

Q8NGV5
TLIILLSVLYPRLHS

OR2H1

41

Q9GZK4
PLHIRETLLFTSSLI

RNF139

171

Q8WU17
ELLLLLQPLSVLTFH

RUSC1

646

Q9BVN2
IDHIPNTIRTLLSTL

THADA

1376

Q6YHU6
PLLLSHTLQELLARD

SNX8

61

Q9Y5X2
HLSDLFSPLPILELT

LRRC41

526

Q15345
SFLRIPSLHLLLFTS

LGI4

71

Q8N135
SLVILFIHLTLPSLL

NPHP3

361

Q7Z494
YISLLDLPLSLLHTQ

PIGL

191

Q9Y2B2
LLHILSHVPSTDLIL

FBXL18

36

Q96ME1
VSAVRLFPLSGHLLL

CDC40

291

O60508
LCTALHLPSSLFLLL

TAOK2

1006

Q9UL54
SILQRPLSLPSLHVF

OVCA2

161

Q8WZ82
LLTLHPIEIARQLTL

SOS1

776

Q07889
FLETPLLSNVISLLH

URB1

1866

O60287
LPDNSILHRLISELL

SORBS2

751

O94875
DVLLHSLLTQPIFLA

SLC23A3

486

Q6PIS1
HILPAFRVLSSLLSS

STK36

471

Q9NRP7
LPGLLLSLLRHSQES

STK36

501

Q9NRP7
LLSLLAHTARVLSPS

STK36

1081

Q9NRP7
GPLRALVLLLSLSFH

SLC39A2

161

Q9NP94
SLFHILVTPLFLLSS

ABCC8

581

Q09428
PLVTAILDSQLRLHL

ANHX

41

E9PGG2
FSPLRISEKVLLHLL

CNNM3

511

Q8NE01
LAALELILHLAPRLS

PIK3R4

396

Q99570
PVVFLLIRLLTHLAL

RNF213

4576

Q63HN8
HLLIDLTSFLLSLFS

SLC30A8

106

Q8IWU4
SLVHESFLDLSLPVL

USP16

376

Q9Y5T5
APPFILLSHLSLTLR

TRPM5

1011

Q9NZQ8
TVVLLVLLALAPLFH

SLC26A1

421

Q9H2B4
SLLHACPLLSTLRLQ

TONSL

1151

Q96HA7
GLVPSRFLTLLAHLV

TMEM107

6

Q6UX40
HCLAATLLPSLLLSL

TREH

566

O43280
LPFIVSHRLSNTLSL

TPP2

906

P29144
LSLFSHLLEILQSPR

WDFY4

1481

Q6ZS81
SEDLVSIHLPLSRTL

UBR1

601

Q8IWV7
RTLTPTLEALLHFLL

TMPRSS9

81

Q7Z410
TLEALLHFLLRPLQT

TMPRSS9

86

Q7Z410
LHFLLRPLQTLSLGL

TMPRSS9

91

Q7Z410
LLLLLLLSLPHTQAA

SEMA6C

11

Q9H3T2
ANVLHRPIILLDSLS

VCPIP1

296

Q96JH7
LRLPRLLLLDLSHNS

VASN

166

Q6EMK4
SLLHLTFLGFSITLL

ZACN

6

Q401N2
ILLPLHRALTELFFV

ZZEF1

2891

O43149
TLLAFPLLLLHAERI

PIGO

841

Q8TEQ8
PLLLLHAERISLVFL

PIGO

846

Q8TEQ8
SPAFLLCLPLLHLLS

ULBP1

6

Q9BZM6
LRHLLNLVSALEPSV

USP34

441

Q70CQ2
LSLQLILLLIPSISH

UNQ5830/PRO19650/PRO19816

6

Q6UY13
LLDDIVLTHSLFLPT

RAPGEFL1

176

Q9UHV5
RIPHSLHIVLLSSLD

VN1R3

176

Q9BXE9
LIELHSPDSRNTLIL

SNTB2

266

Q13425
LTHLSLASLQRLPEL

TSKU

231

Q8WUA8
SLSIDLTFHLLRTLL

UCN

86

P55089
LFDLTTLIHPRSAAI

TRPC4

796

Q9UBN4
DPALILHLTSVLLFQ

UFL1

681

O94874
VATRLLHSPLFQLLI

ULK4

501

Q96C45
LLAALLHSPQLVERL

NCBP2AS2

6

Q69YL0