Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	extracellular matrix	ADAMTS10 TRIL ADAMTSL1 FBN1 WNT6 SPOCK2 MMP2 SSPOP SOD3	3.07e-05	656	52	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS10 TRIL ADAMTSL1 FBN1 WNT6 SPOCK2 MMP2 SSPOP SOD3	3.15e-05	658	52	9	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTS10 ADAMTSL1 FBN1 SPOCK2 MMP2 SSPOP SOD3	3.22e-04	530	52	7	GO:0062023
GeneOntologyCellularComponent	microfibril	ADAMTS10 FBN1	4.65e-04	13	52	2	GO:0001527
GeneOntologyCellularComponent	actin-based cell projection	CORO1A ERBB2 LOXHD1 MYO7A PROM2	6.26e-04	278	52	5	GO:0098858
GeneOntologyCellularComponent	stereocilium	CORO1A LOXHD1 MYO7A	6.77e-04	69	52	3	GO:0032420
GeneOntologyCellularComponent	stereocilium bundle	CORO1A LOXHD1 MYO7A	1.00e-03	79	52	3	GO:0032421
HumanPheno	Broad metatarsal	ADAMTS10 FBN1 MMP2	4.65e-06	13	14	3	HP:0001783
HumanPheno	Broad metacarpals	ADAMTS10 FBN1 MMP2	1.56e-05	19	14	3	HP:0001230
HumanPheno	Broad skull	ADAMTS10 FBN1	2.10e-05	3	14	2	HP:0002682
HumanPheno	Thin bony cortex	ADAMTS10 FBN1 MMP2	3.23e-05	24	14	3	HP:0002753
HumanPheno	Microspherophakia	ADAMTS10 FBN1	4.20e-05	4	14	2	HP:0030961
HumanPheno	Comedo	LRP1 NEK9	4.20e-05	4	14	2	HP:0025249
HumanPheno	Broad ribs	ADAMTS10 FBN1 NEK9	4.65e-05	27	14	3	HP:0000885
HumanPheno	Spherophakia	ADAMTS10 FBN1	6.98e-05	5	14	2	HP:0034375
Domain	EGF_3	ATRN FBN1 LRP1 SSPOP NOTCH4 CRB2	3.72e-05	235	50	6	PS50026
Domain	EGF_1	ATRN FBN1 LRP1 SSPOP NOTCH4 CRB2	5.87e-05	255	50	6	PS00022
Domain	Growth_fac_rcpt_	ATRN ERBB2 FBN1 LRP1 NOTCH4	5.96e-05	156	50	5	IPR009030
Domain	EGF_2	ATRN FBN1 LRP1 SSPOP NOTCH4 CRB2	7.26e-05	265	50	6	PS01186
Domain	Kringle-like	SEL1L PRSS12 MMP2	8.48e-05	32	50	3	IPR013806
Domain	EGF_Ca-bd_CS	FBN1 LRP1 NOTCH4 CRB2	1.31e-04	97	50	4	IPR018097
Domain	EGF_CA	FBN1 LRP1 NOTCH4 CRB2	1.42e-04	99	50	4	PS01187
Domain	ASX_HYDROXYL	FBN1 LRP1 NOTCH4 CRB2	1.47e-04	100	50	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN1 LRP1 NOTCH4 CRB2	1.85e-04	106	50	4	IPR000152
Domain	6-blade_b-propeller_TolB-like	WDR6 LRP1 APEH	2.53e-04	46	50	3	IPR011042
Domain	LDLRA_1	PKD1 LRP1 SSPOP	2.87e-04	48	50	3	PS01209
Domain	LDLRA_2	PKD1 LRP1 SSPOP	3.05e-04	49	50	3	PS50068
Domain	EGF_CA	FBN1 LRP1 NOTCH4 CRB2	3.16e-04	122	50	4	SM00179
Domain	EGF-like_Ca-bd_dom	FBN1 LRP1 NOTCH4 CRB2	3.37e-04	124	50	4	IPR001881
Domain	EGF	ATRN LRP1 NOTCH4 CRB2	3.58e-04	126	50	4	PF00008
Domain	EGF	ATRN FBN1 LRP1 NOTCH4 CRB2	4.04e-04	235	50	5	SM00181
Domain	EGF-like_dom	ATRN FBN1 LRP1 NOTCH4 CRB2	5.25e-04	249	50	5	IPR000742
Domain	-	SEL1L MMP2	5.38e-04	13	50	2	2.10.10.10
Domain	FN_type2_col-bd	SEL1L MMP2	6.26e-04	14	50	2	IPR000562
Domain	FN2_2	SEL1L MMP2	6.26e-04	14	50	2	PS51092
Domain	PLAC	ADAMTS10 ADAMTSL1	6.26e-04	14	50	2	PF08686
Domain	fn2	SEL1L MMP2	6.26e-04	14	50	2	PF00040
Domain	FN2_1	SEL1L MMP2	6.26e-04	14	50	2	PS00023
Domain	FN2	SEL1L MMP2	6.26e-04	14	50	2	SM00059
Domain	TSP_1	ADAMTS10 ADAMTSL1 SSPOP	6.40e-04	63	50	3	PF00090
Domain	EGF-like_CS	ATRN FBN1 LRP1 NOTCH4 CRB2	6.50e-04	261	50	5	IPR013032
Domain	TSP1	ADAMTS10 ADAMTSL1 SSPOP	7.02e-04	65	50	3	SM00209
Domain	TSP1_rpt	ADAMTS10 ADAMTSL1 SSPOP	7.02e-04	65	50	3	IPR000884
Domain	TSP1	ADAMTS10 ADAMTSL1 SSPOP	7.02e-04	65	50	3	PS50092
Domain	LH2	LOXHD1 PKD1	1.05e-03	18	50	2	SM00308
Domain	PLAC	ADAMTS10 ADAMTSL1	1.17e-03	19	50	2	PS50900
Domain	PLAC	ADAMTS10 ADAMTSL1	1.17e-03	19	50	2	IPR010909
Domain	RCC1	NEK9 RCC2	1.29e-03	20	50	2	PF00415
Domain	PLAT	LOXHD1 PKD1	1.43e-03	21	50	2	PS50095
Domain	RCC1_1	NEK9 RCC2	1.43e-03	21	50	2	PS00625
Domain	RCC1_2	NEK9 RCC2	1.43e-03	21	50	2	PS00626
Domain	-	LOXHD1 PKD1	1.43e-03	21	50	2	2.60.60.20
Domain	RCC1_3	NEK9 RCC2	1.43e-03	21	50	2	PS50012
Domain	PLAT	LOXHD1 PKD1	1.43e-03	21	50	2	PF01477
Domain	PLAT/LH2_dom	LOXHD1 PKD1	1.43e-03	21	50	2	IPR001024
Domain	Reg_chr_condens	NEK9 RCC2	1.57e-03	22	50	2	IPR000408
Domain	-	NEK9 RCC2	1.57e-03	22	50	2	2.130.10.30
Domain	Quino_amine_DH_bsu	WDR6 WDR86	1.57e-03	22	50	2	IPR011044
Domain	EGF_CA	FBN1 LRP1 NOTCH4	1.58e-03	86	50	3	PF07645
Domain	RCC1/BLIP-II	NEK9 RCC2	1.71e-03	23	50	2	IPR009091
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTSL1	1.87e-03	24	50	2	IPR013273
Domain	cEGF	FBN1 LRP1	2.19e-03	26	50	2	IPR026823
Domain	cEGF	FBN1 LRP1	2.19e-03	26	50	2	PF12662
Domain	LRRNT	TRIL LRRTM2 PKD1	2.30e-03	98	50	3	IPR000372
Domain	LRRNT	TRIL LRRTM2 PKD1	2.30e-03	98	50	3	SM00013
Domain	hEGF	NOTCH4 CRB2	2.54e-03	28	50	2	PF12661
Domain	GPS	PKD1 ADGRG4	3.73e-03	34	50	2	SM00303
Domain	GPS	PKD1 ADGRG4	3.95e-03	35	50	2	PF01825
Domain	GPS	PKD1 ADGRG4	4.18e-03	36	50	2	PS50221
Domain	GPS	PKD1 ADGRG4	4.41e-03	37	50	2	IPR000203
Domain	-	LRP1 APEH	4.89e-03	39	50	2	2.120.10.30
Domain	WD40	CORO1A WDR6 WDR86 EIF3I	5.05e-03	259	50	4	PF00400
Domain	LDLR_class-A_CS	LRP1 SSPOP	5.13e-03	40	50	2	IPR023415
Domain	WD40	CORO1A WDR6 WDR86 EIF3I	5.69e-03	268	50	4	SM00320
Domain	WD40_repeat	CORO1A WDR6 WDR86 EIF3I	5.99e-03	272	50	4	IPR001680
Domain	Ldl_recept_a	LRP1 SSPOP	6.46e-03	45	50	2	PF00057
Domain	WD_REPEATS_1	CORO1A WDR6 WDR86 EIF3I	6.47e-03	278	50	4	PS00678
Domain	WD_REPEATS_2	CORO1A WDR6 WDR86 EIF3I	6.55e-03	279	50	4	PS50082
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS10 ADAMTSL1 SSPOP NOTCH4	2.32e-05	68	35	4	M27303
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTSL1 SSPOP	1.21e-04	39	35	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTSL1 SSPOP	1.21e-04	39	35	3	MM15165
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS10 ADAMTSL1 SSPOP NOTCH4	4.16e-04	143	35	4	M27275
Pathway	WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_5	SEL1L LRP1	6.16e-04	15	35	2	M42552
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	WNT6 PKD1 MMP2 NOTCH4	6.51e-04	161	35	4	M39770
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	ERBB2 NOTCH4	7.03e-04	16	35	2	M47424
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	SEL1L NOTCH4	8.94e-04	18	35	2	M614
Pathway	WP_FAMILIAL_HYPERLIPIDEMIA_TYPE_1	SEL1L LRP1	8.94e-04	18	35	2	M42559
Pubmed	MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.	FBN1 MMP2	2.28e-06	2	53	2	22550139
Pubmed	MMP-2 downregulation mediates differential regulation of cell death via ErbB-2 in glioma xenografts.	ERBB2 MMP2	2.28e-06	2	53	2	19578738
Pubmed	ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.	ADAMTS10 FBN1	2.28e-06	2	53	2	21402694
Pubmed	Exome sequencing identified new mutations in a Marfan syndrome family.	FBN1 LRP1	2.28e-06	2	53	2	24484584
Pubmed	Effect of androgen blockade on HER-2 and matrix metalloproteinase-2 expression on bone marrow micrometastasis and stromal cells in men with prostate cancer.	ERBB2 MMP2	2.28e-06	2	53	2	23766685
Pubmed	Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.	ERBB2 MMP2 NOTCH4	4.36e-06	21	53	3	22932696
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS10 ADAMTSL1 MMP2 SSPOP	5.39e-06	75	53	4	20637190
Pubmed	Clinical implications of HER-2/neu overexpression and proteolytic activity imbalance in breast cancer.	ERBB2 MMP2	6.83e-06	3	53	2	17613170
Pubmed	[Replicative association analysis of genetic markers of cognitive traits with Alzheimer's disease in a Russian population].	CSMD1 NOTCH4	6.83e-06	3	53	2	25845235
Pubmed	A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.	FBN1 PKD1	6.83e-06	3	53	2	24071006
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	ADAMTS10 FBN1	6.83e-06	3	53	2	30201140
Pubmed	Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.	FBN1 MMP2	6.83e-06	3	53	2	17641224
Pubmed	Gelatinolytic activities (matrix metalloproteinase-2 and -9) and soluble extracellular domain of Her-2/neu in pleural effusions.	ERBB2 MMP2	6.83e-06	3	53	2	17611666
Pubmed	Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.	LRP1 MMP2	6.83e-06	3	53	2	19176371
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	ADAMTS10 CORO1A ADAMTSL1 CSMD1	8.47e-06	84	53	4	15203218
Pubmed	Primary Cilia Deficiency Induces Intracranial Aneurysm.	PKD1 MMP2	1.36e-05	4	53	2	28800037
Pubmed	Weill-Marchesani Syndrome	ADAMTS10 FBN1	1.36e-05	4	53	2	20301293
Pubmed	Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression.	ERBB2 LRP1	1.36e-05	4	53	2	20558745
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	SEL1L DNHD1 CD164L2 ADAMTSL1 PROM2 TMEM59 SPOCK2 TAFA5 CSMD1	1.64e-05	985	53	9	12975309
Pubmed	Expression of c-erbB receptors, MMPs and VEGF in squamous cell carcinoma of the head and neck.	ERBB2 MMP2	2.27e-05	5	53	2	15254682
Pubmed	Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.	ERBB2 MMP2	3.40e-05	6	53	2	15569994
Pubmed	Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins.	SPOCK2 MMP2	4.76e-05	7	53	2	12810672
Pubmed	Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity.	MYO7A MMP2	6.34e-05	8	53	2	31600777
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATRN ERBB2 PROM2 ZNF587 KIAA1328 LRP1 TAFA5 CSMD1 SSPOP NEK9	7.28e-05	1489	53	10	28611215
Pubmed	A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.	LOXHD1 MYO7A	1.02e-04	10	53	2	17329413
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ATRN LOXHD1 MYO7A PKD1 MMP2 ITGAE SSPOP	1.22e-04	736	53	7	29676528
Pubmed	Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors.	ERBB2 MMP2	1.24e-04	11	53	2	10821760
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	ADAMTSL1 FBN1 SPOCK2 SSPOP	1.50e-04	175	53	4	28071719
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	FBN1 LRP1 SSPOP	1.77e-04	71	53	3	33541421
Pubmed	Pigmentation-related genes and their implication in malignant melanoma susceptibility.	ATRN MYO7A	2.05e-04	14	53	2	19320733
Pubmed	Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.	ERBB2 PKD1	2.05e-04	14	53	2	16400024
Pubmed	Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.	CORO1A MYO7A	2.05e-04	14	53	2	26754646
Pubmed	Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice.	ERBB2 MYO7A	2.05e-04	14	53	2	19936227
Pubmed	Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression.	ERBB2 NOTCH4	2.05e-04	14	53	2	21402699
Pubmed	Platelet storage pool deficiency associated with inherited abnormalities of the inner ear in the mouse pigment mutants muted and mocha.	ATRN FBN1	2.05e-04	14	53	2	1912584
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	CSMD1 NOTCH4	2.36e-04	15	53	2	23583980
Pubmed	c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.	WNT6 PKD1	2.70e-04	16	53	2	22677559
Pubmed	A comprehensive family-based replication study of schizophrenia genes.	AS3MT NOTCH4	3.05e-04	17	53	2	23894747
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS10 FBN1	3.43e-04	18	53	2	35503090
Pubmed	Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse.	LOXHD1 MYO7A	3.43e-04	18	53	2	33087486
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	SEL1L TMEM59 LRP1 EIF3I RCC2	4.37e-04	418	53	5	35338135
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	SEL1L ATRN ERBB2 FBN1 TMEM59 LRP1 MMP2 NEK9	4.40e-04	1201	53	8	35696571
Pubmed	Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.	FBN1 WNT6	4.70e-04	21	53	2	17943183
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	FBN1 MMP2 SOD3	5.01e-04	101	53	3	20551380
Pubmed	RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons.	TRIL MMP2	5.16e-04	22	53	2	33903225
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ATRN ADAMTSL1 SSPOP	5.61e-04	105	53	3	9628581
Pubmed	GATA6 Regulates Aortic Valve Remodeling, and Its Haploinsufficiency Leads to Right-Left Type Bicuspid Aortic Valve.	FBN1 MMP2	5.65e-04	23	53	2	29567669
Pubmed	Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years.	SEL1L KIAA1328	6.16e-04	24	53	2	24347629
Pubmed	Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.	MTMR6 LRP1	6.16e-04	24	53	2	17452356
Pubmed	Rbpj regulates development of prosensory cells in the mammalian inner ear.	MYO7A NOTCH4	6.16e-04	24	53	2	21420948
Pubmed	Loss of Gata5 in mice leads to bicuspid aortic valve.	ERBB2 NOTCH4	6.16e-04	24	53	2	21633169
Pubmed	Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.	FBN1 NOTCH4	7.80e-04	27	53	2	35894043
Pubmed	Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development.	ERBB2 CRB2	8.40e-04	28	53	2	37846569
Pubmed	EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades.	MMP2 NOTCH4	9.01e-04	29	53	2	24909139
Pubmed	The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.	ERBB2 MMP2	9.01e-04	29	53	2	19094228
Pubmed	Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms.	MMP2 NOTCH4	9.01e-04	29	53	2	24971735
Pubmed	ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.	FBN1 MMP2	9.64e-04	30	53	2	32882513
Pubmed	Heritable Thoracic Aortic Disease Overview	FBN1 PKD1	9.64e-04	30	53	2	20301299
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	ATRN FBN1	1.03e-03	31	53	2	31550482
Pubmed	Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.	ERBB2 MMP2	1.10e-03	32	53	2	31434798
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	ATRN MGAM CORO1A PROM2 APEH CRB2 SOD3	1.15e-03	1070	53	7	23533145
Pubmed	Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.	MYO7A WNT6	1.31e-03	35	53	2	32907846
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	FBN1 MMP2	1.47e-03	37	53	2	34323105
Interaction	PRICKLE4 interactions	USO1 ZNF587 ZNF417	8.97e-06	17	49	3	int:PRICKLE4
GeneFamily	WD repeat domain containing	CORO1A WDR6 WDR86 EIF3I	5.82e-04	262	27	4	362
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ATRN PKD1	1.70e-03	41	27	2	1298
GeneFamily	Actins\|Deafness associated genes	LOXHD1 MYO7A	1.23e-02	113	27	2	1152
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ERBB2 LRP1 ITGAE	2.04e-02	394	27	3	471
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF587 ZNF790 ZNF417 ZNF697	2.09e-02	718	27	4	28
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 PRSS12 LRP1 MMP2 SOD3	9.58e-08	188	53	6	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th1\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CORO1A MYO7A APEH SPOCK2 CRB2	1.91e-06	172	53	5	c0c9a3f5b5fb942b049bc159fd9f21b5b706edd2
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM229A PRSS12 WNT6 LRRTM2 CSMD1	2.19e-06	177	53	5	59cf56c385c324f0844f20003d2b5049a2791e45
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTS10 ADAMTSL1 FBN1 LRP1 MMP2	2.25e-06	178	53	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 FBN1 LRP1 MMP2 SOD3	2.51e-06	182	53	5	f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIL FBN1 LRP1 MMP2 SOD3	2.51e-06	182	53	5	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-MAIT_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S1PR5 CORO1A SCART1 SPOCK2 WDR86	2.72e-06	185	53	5	8314dc608bc837df3037e89afd9db39737374ebc
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 FBN1 LRP1 MMP2 SOD3	2.80e-06	186	53	5	35c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 FBN1 LRP1 MMP2 SOD3	2.80e-06	186	53	5	d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 MMP2 CSMD1	3.02e-06	189	53	5	544d95df910f1b276995624509a7e41b219baca0
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTSL1 FBN1 LRP1 MMP2 ADGRG4	3.02e-06	189	53	5	d531399749409d614adca13d181830c6e3287508
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PRSS12 LRP1 MMP2 SOD3	3.02e-06	189	53	5	0a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.10e-06	190	53	5	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.10e-06	190	53	5	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.18e-06	191	53	5	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 FBN1 LRP1 MMP2 SOD3	3.18e-06	191	53	5	2b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.26e-06	192	53	5	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 MMP2 CSMD1	3.26e-06	192	53	5	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.26e-06	192	53	5	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 MMP2 CSMD1	3.26e-06	192	53	5	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 FBN1 LRP1 MMP2 SOD3	3.26e-06	192	53	5	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 MMP2 CSMD1	3.26e-06	192	53	5	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PRSS12 LRP1 MMP2 SOD3	3.35e-06	193	53	5	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PRSS12 LRP1 MMP2 SOD3	3.35e-06	193	53	5	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PRSS12 LRP1 MMP2 SOD3	3.35e-06	193	53	5	160691b671710be10220803d788c2c961c236af1
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 FBN1 LRP1 MMP2 SOD3	3.43e-06	194	53	5	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 FBN1 LRP1 MMP2 SOD3	3.43e-06	194	53	5	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 MMP2	3.43e-06	194	53	5	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 MMP2	3.43e-06	194	53	5	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTSL1 FBN1 LRP1 MMP2 ADGRG4	3.52e-06	195	53	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 MMP2	3.52e-06	195	53	5	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	S1PR5 CORO1A FBN1 SPOCK2 MMP2	3.52e-06	195	53	5	e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LRP1 MMP2 CSMD1 SOD3	3.61e-06	196	53	5	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.61e-06	196	53	5	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LRP1 MMP2 CSMD1 SOD3	3.61e-06	196	53	5	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.61e-06	196	53	5	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 LRP1 WDR86 TAFA5 MMP2	3.70e-06	197	53	5	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.70e-06	197	53	5	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.70e-06	197	53	5	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	PND14-Mesenchymal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS10 FBN1 LRP1 MMP2 SOD3	3.70e-06	197	53	5	9a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LOXHD1 LRP1 WDR86	3.70e-06	197	53	5	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TRIL FBN1 LRP1 MMP2 SOD3	3.89e-06	199	53	5	95d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TRIL FBN1 LRP1 MMP2 SOD3	3.89e-06	199	53	5	6a0df9a2f30480043f9c1d7fbdede17eb0910cac
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FBN1 LRP1 MMP2 CLUL1 SOD3	3.98e-06	200	53	5	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 MYO7A PRSS12 LRP1 MMP2	3.98e-06	200	53	5	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 PRSS12 LRP1 WDR86 MMP2	3.98e-06	200	53	5	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 PRSS12 LRP1 MINAR1 MMP2	3.98e-06	200	53	5	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FBN1 LRP1 MMP2 CLUL1 SOD3	3.98e-06	200	53	5	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	Skin-Fibroblasts\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	ADAMTS10 FBN1 LRP1 MMP2 SOD3	3.98e-06	200	53	5	f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	FBN1 PRSS12 LRP1 WDR86 MMP2	3.98e-06	200	53	5	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 MYO7A PRSS12 LRP1 MMP2	3.98e-06	200	53	5	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRIL FBN1 LRRTM2 MMP2 ZNF697	3.98e-06	200	53	5	29054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 FBN1 LRP1 MMP2 ADGRG4	3.98e-06	200	53	5	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	WDR86 CSMD1 SOD3 ZNF697	2.75e-05	146	53	4	2ac9b487a7991fdc15444aeb93533030e09825bb
ToppCell	367C-Fibroblasts-Fibroblast-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 LRP1 MMP2 SOD3	3.39e-05	154	53	4	dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell	367C-Fibroblasts-Fibroblast-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 LRP1 MMP2 SOD3	3.39e-05	154	53	4	4bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CORO1A ITGAE SSPOP ADGRG4	3.84e-05	159	53	4	8d958d79f5eb3ab683d1245ae7f4f22a2cefbc55
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-MAIT_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S1PR5 CORO1A SCART1 SPOCK2	4.55e-05	166	53	4	e4f14b2dd8c6199fa27cc3e3beeda681a3b5b889
ToppCell	Severe-Lymphoid-NK-CD8_T\|Severe / Condition, Lineage, Cell class and cell subclass	ADAMTS10 CORO1A SPOCK2 ITGAE	4.65e-05	167	53	4	8d41015871616ab7eced5104cd8f70d0efe504f2
ToppCell	droplet-Kidney-nan-24m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S1PR5 CORO1A WNT6 LRP1	4.65e-05	167	53	4	2ee1660be117e20f24557522345572d11cbee813
ToppCell	Adult-Mesenchymal-chondrocyte-D175\|Adult / Lineage, Cell type, age group and donor	PROM2 ZNF587 NOTCH4 SOD3	4.76e-05	168	53	4	14071b961c9bdb54a8259b12a88237b802cbde36
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 SOD3	4.87e-05	169	53	4	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 SOD3	4.87e-05	169	53	4	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	droplet-Thymus-nan-18m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164L2 ERBB2 SOD3 OCSTAMP	4.87e-05	169	53	4	4ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 SOD3	4.87e-05	169	53	4	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	Healthy_donor-MAIT\|World / disease group, cell group and cell class (v2)	S1PR5 SCART1 SPOCK2 WDR86	5.22e-05	172	53	4	6524eb2be1c78700ad367e62624a4d7eb48b54f0
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTSL1 FBN1 LRP1 MMP2	5.22e-05	172	53	4	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ERBB2 TMEM229A PROM2 SPOCK2	5.22e-05	172	53	4	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 LRP1 MMP2 SOD3	5.46e-05	174	53	4	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LRP1 MMP2 SOD3	5.46e-05	174	53	4	68a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM FBN1 LRP1 SOD3	5.46e-05	174	53	4	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDR86 ITGAE SSPOP OCSTAMP	5.58e-05	175	53	4	4655d3daa95e8ffa7d5ee4180de06b2fec361bfb
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ADAMTSL1 FBN1 MMP2 SOD3	5.71e-05	176	53	4	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	10x3'2.3-week_17-19-Lymphocytic_T-T_NK-NK_T_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS10 S1PR5 CORO1A SPOCK2	5.96e-05	178	53	4	a34bb693b72684cbd97ac9efff77d2d14e41be75
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-MAIT_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	S1PR5 CORO1A SPOCK2 WDR86	5.96e-05	178	53	4	f52f837e948deb6a2d031325f49891bca8d375da
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TRIL ERBB2 LOXHD1 SPOCK2	6.09e-05	179	53	4	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADAMTSL1 FBN1 LRP1 MMP2	6.23e-05	180	53	4	9adebde5f4ca6dcb90e9113622862e14298465ac
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRIL PRSS12 LRP1 SOD3	6.36e-05	181	53	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 WNT6 MMP2	6.36e-05	181	53	4	269b39ac65790061d54eab47a8eeb024403f0348
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 WNT6 MMP2	6.36e-05	181	53	4	cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 LRP1 TAFA5 MMP2	6.36e-05	181	53	4	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 WNT6 MMP2	6.36e-05	181	53	4	c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 LRP1 TAFA5 MMP2	6.36e-05	181	53	4	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 LRP1 MMP2 SOD3	6.36e-05	181	53	4	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 LRP1 TAFA5 MMP2	6.50e-05	182	53	4	e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT6 LRRTM2 TAFA5 CSMD1	6.50e-05	182	53	4	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 LRP1 MMP2 SOD3	6.50e-05	182	53	4	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 LRP1 MMP2 SOD3	6.50e-05	182	53	4	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT6 LRRTM2 TAFA5 CSMD1	6.50e-05	182	53	4	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT6 LRRTM2 TAFA5 CSMD1	6.50e-05	182	53	4	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LRP1 MMP2 SOD3	6.64e-05	183	53	4	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LRP1 MMP2 SOD3	6.64e-05	183	53	4	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WNT6 SPOCK2 CLUL1 CRB2	6.64e-05	183	53	4	03649492c37f9b274a1caf3e2132ce2915cf1df5
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 SPOCK2 MMP2 ZNF697	6.64e-05	183	53	4	351d575339038bd4a66f408da518c567444208e8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM LOXHD1 CSMD1 SSPOP	6.78e-05	184	53	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 FBN1 LRP1 ADGRG4	6.78e-05	184	53	4	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM LOXHD1 CSMD1 SSPOP	6.78e-05	184	53	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM LOXHD1 CSMD1 SSPOP	6.78e-05	184	53	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 LRP1 MMP2	6.78e-05	184	53	4	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSLNL WDR86 MMP2 CRB2	6.78e-05	184	53	4	1c857126c0ea0671f0d60b048efca288d348d653
Drug	cyclopentylcarbamoylphosphonic acid	MGAM MMP2	4.73e-06	2	50	2	CID010198038
Disease	Weill-Marchesani syndrome	ADAMTS10 FBN1	8.43e-06	3	50	2	C0265313
Disease	Weill-Marchesani Syndrome, Autosomal Dominant	ADAMTS10 FBN1	8.43e-06	3	50	2	C1869115
Disease	Weill-Marchesani Syndrome, Autosomal Recessive	ADAMTS10 FBN1	8.43e-06	3	50	2	C1869114
Disease	Weill-Marchesani syndrome (implicated_via_orthology)	ADAMTS10 FBN1	8.43e-06	3	50	2	DOID:0050475 (implicated_via_orthology)
Disease	Weill-Marchesani syndrome	ADAMTS10 FBN1	1.68e-05	4	50	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	ADAMTS10 FBN1	1.68e-05	4	50	2	DOID:0050475 (is_implicated_in)
Disease	Aortic Rupture	FBN1 MMP2	2.80e-05	5	50	2	C0003496
Disease	Aortic Aneurysm, Ruptured	FBN1 MMP2	2.80e-05	5	50	2	C0741160
Disease	Aortic Aneurysm, Thoracic	FBN1 MMP2	5.88e-05	7	50	2	C0162872
Disease	Aortic Aneurysm, Thoracoabdominal	FBN1 MMP2	5.88e-05	7	50	2	C0340630
Disease	Marfan Syndrome, Type I	FBN1 MMP2	1.01e-04	9	50	2	C4721845
Disease	Familial thoracic aortic aneurysm and aortic dissection	ADAMTS10 FBN1 PKD1	1.01e-04	53	50	3	C4707243
Disease	aortic aneurysm	FBN1 LRP1	1.26e-04	10	50	2	EFO_0001666
Disease	Marfan Syndrome	FBN1 MMP2	1.53e-04	11	50	2	C0024796
Disease	intracranial aneurysm (is_implicated_in)	PKD1 MMP2	1.84e-04	12	50	2	DOID:10941 (is_implicated_in)
Disease	feeling nervous measurement	MGAM CSMD1 NOTCH4	4.39e-04	87	50	3	EFO_0009597
Disease	laryngeal squamous cell carcinoma (is_marker_for)	ERBB2 MMP2	4.72e-04	19	50	2	DOID:2876 (is_marker_for)
Disease	Nasopharyngeal carcinoma	ERBB2 MMP2	6.36e-04	22	50	2	C2931822
Disease	systemic scleroderma (is_implicated_in)	FBN1 NOTCH4	7.58e-04	24	50	2	DOID:418 (is_implicated_in)
Disease	pallidum volume change measurement, age at assessment	TAFA5 CSMD1	8.23e-04	25	50	2	EFO_0008007, EFO_0021494
Disease	lumbar disc degeneration	SPOCK2 CSMD1	1.03e-03	28	50	2	EFO_0004994
Disease	spontaneous coronary artery dissection	FBN1 LRP1	1.27e-03	31	50	2	EFO_0010820
Disease	liver cirrhosis (biomarker_via_orthology)	FBN1 MMP2	1.52e-03	34	50	2	DOID:5082 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GSRCWGESSEDCQSL	ERBB2	201	P04626
ECLANGLWSGSETRC	CSMD1	2661	Q96PZ7
SCNWEESGLLGSCFS	LINC00269	11	Q8N2A0
LCCGWLRLDNSSDGS	ADGRG4	3001	Q8IZF6
SVDWSRDGGLICTSC	CORO1A	181	P31146
CDGASNGAWLDSITC	DNHD1	2086	Q96M86
GNWSLCSRSCDAGVR	ADAMTS10	891	Q9H324
SCTDTGRSDGFLWCS	MMP2	246	P08253
DLCGWRIRSLACGKS	RCC2	426	Q9P258
DGRLLCGATLLSSCW	PRSS12	656	P56730
VGLSGNLWECSARIC	LRRTM2	306	O43300
DLDSDSWCLLGTDSC	NEK9	961	Q8TD19
CSDGWDRTSQVCSLG	MTMR6	336	Q9Y217
ASCLEGLGSFRCLCW	CRB2	236	Q5IJ48
ANGRCLSSRQWECDG	LRP1	2866	Q07954
SSDVRGCSCFSDWQG	ATRN	301	O75882
NGASAENCTARGCIW	MGAM	971	O43451
CNCWLAKDRGDGITS	LOXHD1	1521	Q8IVV2
WSVDRLATCSASCGN	ADAMTSL1	1491	Q8N6G6
RSCLGCLREWSSGSQ	ITGAE	746	P38570
CLREWSSGSQLCEDL	ITGAE	751	P38570
AWQLSCLANLASRCG	MSLNL	91	Q96KJ4
CLLKSNCDGWLLGTS	KIAA1328	411	Q86T90
LKSQCCSSLGAAWGS	FBN1	871	P35555
SADNSCRLWDCETGK	EIF3I	71	Q13347
AWLCLCGRGLQGSAS	C17orf107	151	Q6ZR85
NCWILDLGSGSGRDC	AS3MT	71	Q9HBK9
GDGARNLSSCVWEQC	CD164L2	66	Q6UWJ8
LGWNCLGRLDACSTV	S1PR5	171	Q9H228
LAALSEQGWCLCGAA	PKD1	221	P98161
WCCSDASGSNSESLR	MINAR1	681	Q9UPX6
EGCDLLINRSGWTCT	TAFA5	106	Q7Z5A7
CGGLFSTDSLSNWCA	USO1	426	O60763
SWCDRSCGGGQSLRS	SSPOP	4016	A2VEC9
ELSWGLGLRTCGACS	TMEM229A	321	B2RXF0
CTSDGREDGRLWCAT	SEL1L	141	Q9UBV2
GEGKELWSCRDLSCN	OCSTAMP	496	Q9BR26
CDWVALGACGSASNI	NOTCH4	1951	Q99466
CSLLPLGCWSADSQR	APEH	361	P13798
RESLADSWGECRSCL	CLUL1	106	Q15846
ESDGFLRCLSLNSGW	TMEM59	226	Q9BXS4
ARCQGDCAGALSWAR	PROM2	301	Q8N271
CSCLLLAAGASDAWT	SOD3	6	P08294
ENLALISSLGCWCGS	ZNF587	46	Q96SQ5
LDGNGWTCDCRLRGL	TRIL	356	Q7L0X0
ENLALISSLGCWCGS	ZNF417	46	Q8TAU3
GLSGSCALRTCWQKL	WNT6	226	Q9Y6F9
SCRGNESSLWECSLG	SCART1	96	Q4G0T1
DRCTLSSACLIGDAW	WDR6	156	Q9NNW5
CADCGKSFSWRADLL	ZNF697	291	Q5TEC3
SLDCLCFRGDWEGNT	ZNF790	111	Q6PG37
DGTARLWSTADGQCC	WDR86	36	Q86TI4
LWSTADGQCCALLQG	WDR86	41	Q86TI4
SSGDCWCVDQLGLEL	SPOCK2	351	Q92563
SSRECRVWLSLGCSD	MYO7A	1521	Q13402
RVWLSLGCSDLGCAA	MYO7A	1526	Q13402