Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell junction organization

ABL2 CHAT LRTM2 ITGAM ACE SYNGAP1 DLC1 NRXN1 BSN CACNB4 STON1 TNC PCDHB6 PCDHB2 PTPN23 SORBS1 NECTIN3 SEZ6L2 HDAC7 PCDHB16 DNAJA3 NPTN SHANK2 SIPA1L1 NEURL1 MACF1 MDGA1 TNS1 NPAS4 SMAD7

7.45e-0797423530GO:0034330
GeneOntologyBiologicalProcesscell junction assembly

LRTM2 ACE DLC1 NRXN1 BSN STON1 PCDHB6 PCDHB2 SORBS1 NECTIN3 HDAC7 PCDHB16 NPTN SHANK2 SIPA1L1 NEURL1 MACF1 MDGA1 TNS1 NPAS4 SMAD7

2.49e-0656923521GO:0034329
GeneOntologyBiologicalProcesssynapse organization

ABL2 CHAT LRTM2 ITGAM SYNGAP1 NRXN1 BSN CACNB4 TNC PCDHB6 PCDHB2 SORBS1 NECTIN3 SEZ6L2 PCDHB16 DNAJA3 NPTN SHANK2 SIPA1L1 NEURL1 MDGA1 NPAS4

1.30e-0568523522GO:0050808
GeneOntologyBiologicalProcesslocomotory behavior

ABL2 CHAT ALK CNTN1 BAHCC1 CACNB4 DRD3 FEZF2 FIGN SEZ6L2 CELSR1 SHANK2 OTOG

2.45e-0528423513GO:0007626
GeneOntologyBiologicalProcesssynapse assembly

LRTM2 NRXN1 BSN PCDHB6 PCDHB2 NECTIN3 PCDHB16 NPTN SHANK2 SIPA1L1 NEURL1 MDGA1 NPAS4

5.65e-0530823513GO:0007416
Domain-

RNF130 EXPH5 TRIM49C KDM5D RNF215 MTMR3 MLLT6 BSN FGD3 TRIM49 BAZ2B KAT6A PHRF1 MIB2 KMT2D NEURL1 RNF139 TRIM49B

1.54e-05449234183.30.40.10
DomainNEUZ

NEURL2 NEURL1 NEURL4

1.91e-0552343SM00588
DomainNHR

NEURL2 NEURL1 NEURL4

1.91e-0552343PS51065
DomainNHR_dom

NEURL2 NEURL1 NEURL4

1.91e-0552343IPR006573
DomainNeuralized

NEURL2 NEURL1 NEURL4

1.91e-0552343PF07177
DomainZnf_RING/FYVE/PHD

RNF130 EXPH5 TRIM49C KDM5D RNF215 MTMR3 MLLT6 BSN FGD3 TRIM49 BAZ2B KAT6A PHRF1 MIB2 KMT2D NEURL1 RNF139 TRIM49B

2.07e-0545923418IPR013083
DomainZnf_FYVE_PHD

KDM5D MTMR3 MLLT6 BSN FGD3 BAZ2B KAT6A PHRF1 KMT2D

1.00e-041472349IPR011011
DomainGCR_153/162

GPR162 GPR153

1.56e-0422342IPR022347
DomainLRR

PIDD1 LRTM2 LRG1 CIITA LRRC56 NLRC5 CEP97 LRRC58 LRCH4 LRRC36

2.31e-0420123410PS51450
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PDE2A PCNX3 TRIO KIF26A EDC4 ABCA7 REXO1 CASZ1 MTMR3 LRRC56 NLRC5 MLLT6 PLK3 BAHCC1 SHROOM3 ATP13A1 KAT6A HECTD4 MIB2 TEP1 HDAC7 DHX30 CCDC142 NCOR2 CELSR1 KMT2D SHANK2 ZNF408 HPS6 DISP2 DOT1L SOWAHB SMAD7

2.45e-1211052433335748872
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

WBP1 KDM5D SYNGAP1 ZNF469 TMEM92 PEX5 MLLT6 CAMTA1 BSN MRTFA JCAD SHROOM3 ARHGEF18 NCOR2 LINC00696 EGR2 ZFR NEURL4

1.80e-094302431835044719
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TNK1 NES PDE3B ABL2 TRIO EXPH5 STXBP4 EDC4 ARHGEF17 DLC1 FOXO4 TSC22D4 JCAD SHROOM3 USP43 SORBS1 NCKAP5L HDAC7 ARFGEF3 SIPA1L1 NEURL1 MACF1 CSPP1 OTOG

1.10e-088612432436931259
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BAHCC1 JCAD SHROOM3 BAZ2B HCN3 PHRF1 PTPN23 URGCP ABCB9

4.85e-08103243910819331
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NES PDE2A TRIO EDC4 SYNGAP1 NRXN1 PEX5 BSN CNTN1 CACNB4 SHROOM3 HCN3 HECTD4 ARHGEF18 SORBS1 IPO4 NPTN NCOR2 SHANK2 SIPA1L1 MACF1 ZFR TNS1 NEURL4

8.95e-089632432428671696
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RNF130 PDE3B TRIO INTS3 ZNF767P BDH1 CASZ1 DNAAF5 SHC2 SEMA3B NLRC5 TSC22D4 CAMTA1 MAML3 SHROOM3 LMF1 MAN1C1 KAT6A HECTD4 ARHGEF18 TARS2 TEP1 PCDHB16 DNAH1 ARFGEF3 NCOR2 SHANK2 MAST1 MACF1 AADAT

2.15e-0714892433028611215
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

HIC2 ABCA7 ZNF469 BRD8 SALL2 PEX5 TADA2A BAHCC1 SUPT20H ADAMTS1 FEZF2 TAF1C KAT6A PHRF1 TEP1 NCKAP5L DICER1 DNAJA3 NCOR2 CADPS SIPA1L1 NEURL1 MACF1 SIGLEC1 RSBN1L

3.52e-0711162432531753913
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGEF17 GANAB MTMR3 CAMTA1 SORBS1 PCDHB16 IGDCC4 DHX30 ARFGEF3 CADPS SIPA1L1 MAST1 MACF1 DISP2

1.26e-064072431412693553
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

TRIO CHAT SEMA3B CNTN1 NECTIN3 IGDCC4 NPTN SIGLEC1 MDGA1

2.29e-06162243925826454
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EXPH5 LCMT2 REXO1 CASZ1 AARS2 FAM135A MAML3 ATP13A1 BAZ2B ARHGEF18 PTPN23 DGKD LDB3 MACF1 NEURL4

2.38e-064932431515368895
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

EXPH5 PSMC6 SYNGAP1 BLM SUPT20H RASGRF2 TOGARAM2 PCDHB6 SORBS1 MEI1 ZNF408 ZFR MUC4 CSPP1 RSBN1L

2.63e-064972431536774506
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

NRXN1 CAMTA1 CACNB4 SORBS1 DHX30 SHANK2 CADPS MACF1

3.52e-06128243830995482
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

HIC2 SALL2 NRXN1 CAMTA1 MRTFA PTPN23 DICER1 CADPS SIPA1L1 MACF1

4.65e-062252431012168954
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

TRIO EDC4 PEX5 CEP97 STON1 DICER1 ARFGEF3 SIPA1L1 MACF1

1.79e-05209243936779422
Pubmed

Egr2::cre mediated conditional ablation of dicer disrupts histogenesis of mammalian central auditory nuclei.

CHAT DICER1 EGR2

1.84e-058243323152916
Pubmed

A radial glia-specific role of RhoA in double cortex formation.

NES MRTFA FEZF2 MDGA1

1.85e-0523243422405202
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NES PDE2A TRIO ACAT1 EDC4 ARHGEF17 JMY SYNGAP1 GLUD2 KCNQ3 TSC22D4 BSN CNTN1 CACNB4 TNC SORBS1 DHX30 OR52E2 NPTN SHANK2 CADPS SIPA1L1 MAST1 MACF1 TNS1

2.68e-0514312432537142655
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ABL2 SYNGAP1 BSN CACNB4 TNC HCN3 SORBS1 SH2D5 SHANK2 SIPA1L1 MACF1

3.71e-053472431117114649
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

AARS2 NRXN1 BAHCC1 SORBS1 CADPS SIPA1L1 MACF1

3.80e-05130243712421765
Pubmed

NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.

CIITA NLRC5

4.86e-052243237108368
Pubmed

The transcriptional regulator megakaryoblastic leukemia-1 mediates serum response factor-independent activation of tenascin-C transcription by mechanical stress.

MRTFA TNC

4.86e-052243221705668
Pubmed

Interactions of AMTN, ODAM and SCPPPQ1 proteins of a specialized basal lamina that attaches epithelial cells to tooth mineral.

ODAM AMTN

4.86e-052243228436474
Pubmed

Neur1 and Neur2 are required for hippocampus-dependent spatial memory and synaptic plasticity.

NEURL2 NEURL1

4.86e-052243232644222
Pubmed

Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivator.

CIITA NLRC5

4.86e-052243222711889
Pubmed

Odontogenic ameloblast-associated and amelotin are novel basal lamina components.

ODAM AMTN

4.86e-052243222231912
Pubmed

Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation.

MACF1 SMAD7

4.86e-052243232143362
Pubmed

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.

CIITA NLRC5

4.86e-052243220639463
Pubmed

Regulation of MRTF-A by JMY via a nucleation-independent mechanism.

JMY MRTFA

4.86e-052243230463620
Pubmed

Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution.

JCAD SOWAHB

4.86e-052243227669027
Pubmed

NLRC5: a key regulator of MHC class I-dependent immune responses.

CIITA NLRC5

4.86e-052243223175229
Pubmed

The interaction between F3 immunoglobulin domains and protein tyrosine phosphatases zeta/beta triggers bidirectional signalling between neurons and glial cells.

CNTN1 TNC

4.86e-052243210103110
Pubmed

Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins.

CIITA NLRC5

4.86e-052243222645137
Pubmed

Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism.

PDE2A PDE3B

4.86e-052243233112806
Pubmed

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.

DICER1 KMT2D

4.86e-052243226841698
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TRIO ACAT1 EDC4 BDH1 SYNGAP1 NRXN1 GLUD2 KCNQ3 BSN JCAD CACNB4 ATP13A1 MIB2 SORBS1 DNAJA3 ARFGEF3 ISOC2 SHANK2 CADPS SIPA1L1 MACF1

5.70e-0511392432136417873
Pubmed

Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.

NES NEURL2 NEURL1

7.07e-0512243314960280
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

STXBP4 BLM SALL2 BSN FAM135A SUPT20H SORBS1 IPO4 NCKAP5L ARFGEF3 NCOR2 MACF1 DOT1L ZMYM6

7.65e-055882431438580884
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

ABL2 BLM TAF1C DUSP6 KAT6A LBP TEP1 DNAJA3 SIGLEC1 TP53AIP1

7.84e-053132431020800603
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PHRF1 CPNE5 NCKAP5L KIAA1614 PCDHB16 IGDCC4

7.97e-05101243610997877
Pubmed

Protocadherins.

PCDHB6 PCDHB2 PCDHB16

9.15e-0513243312231349
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CEMIP2 FAM135A MRTFA ADAMTS1 SORBS1 DNAH1 ZMYM6

1.06e-04153243710718198
Pubmed

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

BSN SORBS1 SHANK2

1.16e-0414243316452088
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

JAGN1 EXPH5 BLM DLC1 FOXO4 ATP13A3 PSRC1 TRMT12 CACNB4 PGGHG TNC KAT6A MED1 TARS2 PPCS DICER1 ISOC2 ARSA MAPK15 ZNF79 LRRC36 SMAD7

1.21e-0412932432215342556
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

CASZ1 AARS2 BAHCC1 JCAD SUPT20H SHMT1 NCKAP5L DNAJA3 NCOR2 KMT2D DOT1L

1.25e-043982431135016035
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PDE3B JAGN1 PSMC6 EDC4 DNAAF5 GANAB AARS2 CEP97 NCAPD3 NAT14 TMEM201 ADAMTS1 ATP13A1 IPO4 TARS2 URGCP ARFGEF3 NPTN

1.26e-049422431831073040
Pubmed

Mutation of ARHGAP9 in patients with coronary spastic angina.

TRIO ARHGEF17 DLC1 ARHGAP9

1.42e-0438243419911011
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

ARHGEF17 FGD3 RASGRF2 ARHGEF18

1.42e-0438243411756498
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

GANAB NRXN1 MTMR3 SHROOM3 ARHGAP9

1.43e-0471243533541421
Pubmed

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

TRIM49C TRIM49 TRIM49B

1.44e-0415243319703589
Pubmed

A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse.

NES FEZF2 NECTIN3

1.44e-0415243323727838
Pubmed

Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells.

NES FEZF2 NECTIN3

1.44e-0415243324115331
Pubmed

Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes.

ITGAM SYNGAP1

1.45e-043243229632532
Pubmed

Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.

CHAT TMEM201

1.45e-043243233401680
Pubmed

Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer's disease.

CHAT FEZF2

1.45e-043243235194025
Pubmed

Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges.

NRXN1 MDGA1

1.45e-043243228641112
Pubmed

Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals.

NRXN1 BSN

1.45e-043243234320240
Pubmed

Tensin1 requires protein phosphatase-1alpha in addition to RhoGAP DLC-1 to control cell polarization, migration, and invasion.

DLC1 TNS1

1.45e-043243219826001
Pubmed

The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1.

DLC1 MRTFA

1.45e-043243222139079
Pubmed

NLRC5 exclusively transactivates MHC class I and related genes through a distinctive SXY module.

CIITA NLRC5

1.45e-043243225811463
Pubmed

Tensin1 positively regulates RhoA activity through its interaction with DLC1.

DLC1 TNS1

1.45e-043243226427649
Pubmed

Localization and cellular distribution of CPNE5 in embryonic mouse brain.

NES CPNE5

1.45e-043243218614158
Pubmed

hSSB1 associates with and promotes stability of the BLM helicase.

INTS3 BLM

1.45e-043243228506294
Pubmed

Coordinate transcription of the ADAMTS-1 gene by luteinizing hormone and progesterone receptor.

ADAMTS1 LHCGR

1.45e-043243215256533
Pubmed

Adrenocortical tumorigenesis in transgenic mice expressing the inhibin alpha-subunit promoter/simian virus 40 T-antigen transgene: relationship between ectopic expression of luteinizing hormone receptor and transcription factor GATA-4.

INHA LHCGR

1.45e-043243215256532
Pubmed

The Lin28/let-7 axis is critical for myelination in the peripheral nervous system.

DICER1 EGR2

1.45e-043243226466203
Pubmed

Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.

XKR8 NPTN

1.45e-043243227503893
Pubmed

MAP kinase phosphatase-3 (MKP-3) is transcriptionally and post-translationally up-regulated by hCG and modulates cAMP-induced p21 expression in MA-10 Leydig cells.

DUSP6 LHCGR

1.45e-043243223261984
Pubmed

CircMACF1 alleviates myocardial fibrosis after acute myocardial infarction by suppressing cardiac fibroblast activation via the miR-16-5p/SMAD7 axis.

MACF1 SMAD7

1.45e-043243237713818
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

PCNX3 PSMC6 EDC4 ZNF767P BDH1 CASZ1 BLM BRD8 NCAPD3 SHROOM3 SUPT20H ATP13A1 TAF1C PHRF1 MED1 IPO4 DICER1 DHX30 CELSR1 SHANK2 SIPA1L1 LRCH4 MACF1 RSBN1L

1.46e-0414972432431527615
Pubmed

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

RNF130 EDC4 NLRC5 PSRC1

1.58e-0439243421347282
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TRIO STXBP4 PSMC6 CEMIP2 BLM GANAB MTMR3 USP1 JCAD DUSP6 PTPN23 TARS2 NCKAP5L DNAJA3 NCOR2 KMT2D TNS1 CSPP1 NEURL4

1.62e-0410492431927880917
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

RNF130 PSMC6 HIC2 EDC4 PRDM10 COA6 BRD8 GANAB GID4 ATP13A3 TADA2A USP1 SUPT20H ATP13A1 MED1 SAPCD2 DICER1 DHX30 ZNF408 MRAP RNF139 SOWAHB

1.75e-0413272432232694731
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

ABL2 TRIO SYNGAP1 ARHGEF18 SORBS1 NPTN SHANK2 SIPA1L1 MACF1

1.75e-04281243928706196
Pubmed

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

CASZ1 HECTD4 FIGN

1.76e-0416243321572416
Pubmed

Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse.

CHAT NTN5 EGR2

2.13e-0417243326858598
Pubmed

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

ARHGEF17 FGD3 RASGRF2 ARHGEF18

2.32e-0443243412376548
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

BSN CACNB4 TNC SORBS1 SH2D5 SHANK2 SIPA1L1 MACF1

2.37e-04231243816452087
Pubmed

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

NES SALL2 FEZF2 NECTIN3 CELSR1

2.81e-0482243531073041
Pubmed

Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens.

ITGAM SIGLEC1

2.89e-044243237059107
Pubmed

AF17 facilitates Dot1a nuclear export and upregulates ENaC-mediated Na+ transport in renal collecting duct cells.

MLLT6 DOT1L

2.89e-044243222087315
Pubmed

DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation.

EDC4 DICER1

2.89e-044243223064648
Pubmed

AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha.

MLLT6 DOT1L

2.89e-044243219864429
Pubmed

Structurally distinct LewisX glycans distinguish subpopulations of neural stem/progenitor cells.

NES TNC

2.89e-044243221385876
Pubmed

MicroRNAs are mediators of androgen action in prostate and muscle.

DICER1 NCOR2

2.89e-044243221048966
Pubmed

Pax6 controls radial glia differentiation in the cerebral cortex.

NES TNC

2.89e-04424329856459
Pubmed

Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY.

JMY MRTFA

2.89e-044243222262458
Pubmed

Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination.

BLM TRIM49

2.89e-044243223708797
Pubmed

GluRδ2 assembles four neurexins into trans-synaptic triad to trigger synapse formation.

NRXN1 BSN

2.89e-044243222457515
Pubmed

ARNT2 Tunes Activity-Dependent Gene Expression through NCoR2-Mediated Repression and NPAS4-Mediated Activation.

NCOR2 NPAS4

2.89e-044243230846309
Pubmed

Site-specific HNK-1 epitope on alternatively spliced fibronectin type-III repeats in tenascin-C promotes neurite outgrowth of hippocampal neurons through contactin-1.

CNTN1 TNC

2.89e-044243230629639
Pubmed

Non-cell autonomous control of precerebellar neuron migration by Slit and Robo proteins.

CHAT CNTN1 EGR2

3.01e-0419243329343636
Pubmed

Identification of a genomic reservoir for new TRIM genes in primate genomes.

TRIM49C TRIM49 TRIM49B

3.01e-0419243322144910
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

STXBP4 MTMR3 JCAD SHROOM3 SORBS1 NCKAP5L HDAC7 DNAJA3 SIPA1L1 LRCH4 CSPP1

3.33e-044462431124255178
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

BRIX1 PDE3B STXBP4 MRPL37 LCMT2 CEMIP2 BLM GANAB TSC22D4 FAM135A TMEM201 SHROOM3 ATP13A1 SHMT1 IPO4 TARS2 NCKAP5L DICER1 DHX30 DNAJA3 MACF1 CSPP1 NEURL4

3.35e-0414872432333957083
Pubmed

PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.

NES ARHGEF18 PTPN23

3.52e-0420243332079660
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB6 PCDHB2 PCDHB16

3.52e-0420243311322959
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

ABL2 TRIO STXBP4 ACE GANAB PEX5 CEP97 JCAD TMEM201 SHROOM3 PTPN23 SORBS1 NCKAP5L DNAJA3 SIPA1L1 NEURL4

3.65e-048532431628718761
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

ABL2 MRPL37 INTS3 CASZ1 COA6 DRAXIN CAMTA1 PSRC1 PADI1 MRTFA MAN1C1 HCN3 XKR8 TARS2 PPCS SH2D5 GPR153 MACF1

3.74e-0410312431816710414
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF26A HIC2 CEMIP2 AP5Z1 BSN NCAPD3 SHROOM3 PHRF1 HECTD4 DICER1 KIAA1614 URGCP

3.83e-045292431214621295
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

INTS3 REXO1 BLM BRD8 MRTFA NCAPD3 SPATA19 PHRF1 MED1 HDAC7 URGCP NCOR2 KMT2D ABCB9 SIPA1L1

3.97e-047742431515302935
Cytoband1p36.22

CASZ1 DRAXIN TMEM201 C1orf167

4.41e-053724341p36.22
Cytoband19p13.3

ADAT3 ABCA7 LRG1 REXO1 SHC2 ARHGEF18 DOT1L

2.90e-04237243719p13.3
Cytoband11q25

PRDM10 NCAPD3 SPATA19

3.48e-0426243311q25
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

TRIO FGFR4 CNTN1 NECTIN3 IGDCC4 NPTN SIGLEC1 MDGA1

5.45e-051611488593
GeneFamilyPHD finger proteins

KDM5D MLLT6 BAZ2B KAT6A PHRF1 KMT2D

9.61e-0590148688
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO ARHGEF17 FGD3 RASGRF2 ARHGEF18

2.05e-04661485722
GeneFamilyParkinson disease associated genes|ATPase orphan transporters

ATP13A3 ATP13A1

6.55e-04514821213
GeneFamilyAtaxins|Trinucleotide repeat containing

MAML3 NCOR2 KMT2D

1.08e-03251483775
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

OSBPL7 FGD3 RASGRF2 ARHGEF18 ARHGAP9 DGKD CADPS

1.55e-032061487682
GeneFamilyPDZ domain containing

STXBP4 SHROOM3 LDB3 SHANK2 SIPA1L1 MAST1

1.58e-0315214861220
GeneFamilyRing finger proteins

RNF130 TRIM49C RNF215 TRIM49 PHRF1 NEURL1 RNF139 TRIM49B

1.95e-03275148858
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

WBP1 NES RNF130 PIDD1 ADAM11 ARHGEF17 GPR162 ABCA7 CEMIP2 RNF215 SHC2 SEMA3B MTMR3 PNRC1 MLLT6 PLK3 BAHCC1 SHROOM3 STON1 FEZF2 TNC KAT6A HECTD4 PCDHB2 DGKD MIB2 FIGN TEP1 IGDCC4 CELSR1 ARSA MAPK15 C5orf24 GPR153 LRCH4 DOT1L

4.96e-06146623436PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

PIDD1 ADAM11 ARHGEF17 GPR162 ABCA7 CEMIP2 SYNGAP1 SHC2 SEMA3B MTMR3 PLK3 MRTFA BAHCC1 NAT14 SHROOM3 STON1 FEZF2 KAT6A PCDHB2 DGKD MIB2 FIGN IGDCC4 MAPK15 C5orf24 GPR153 LRCH4 DOT1L

2.21e-05107523428PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
ToppCell(05)_Ciliated-(2)_48hpi|(05)_Ciliated / shred by cell type and Timepoint

LRG1 BLM KCNC3 PLK3 MIB2 CCDC142 ARFGEF3 OTOG

3.89e-071242418fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGAM PRDM10 MTMR3 USP1 FGD3 TRMT12 SAPCD2 NCOR2 ZMYM6

5.22e-07176241990f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 JCAD RASGRF2 TMEM204 USHBP1 DISP2

6.60e-0718124194df7972f88117108698efd06b124b232f8588981
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 JCAD RASGRF2 TMEM204 USHBP1 DISP2

6.60e-071812419cbb530566893281289026bfd93adf721decd4ca3
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A DLC1 RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.06e-0718824195cf060bb8adaefa9964187195d67993c1248ef47
ToppCelldroplet-Fat-SCAT-30m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A DLC1 RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.06e-071882419e901a9bdf00b8e91806f445af66647373bf62661
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A DLC1 JCAD RASGRF2 TMEM204 USHBP1 TNS1

9.06e-07188241905de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A DLC1 RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.06e-071882419449f9602df3c83b2110eb479a00d428d1b55b423
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A JCAD RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.90e-0719024195174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A JCAD RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.90e-07190241990e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A KIF26A TPBGL CEMIP2 JCAD STON1 TMEM204 HDAC7 USHBP1

9.90e-071902419a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A KIF26A TPBGL CEMIP2 JCAD STON1 TMEM204 HDAC7 USHBP1

9.90e-07190241925525fee1da8a808034d9c916159fd0b6b26bce8
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A JCAD RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.90e-071902419c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCelldroplet-Heart-HEART-1m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A PHOSPHO1 JCAD TMEM204 DUSP6 SEZ6L2 USHBP1

1.03e-0619124191aac4f839c2f83dac924fdb5d8d0c76687dacd2a
ToppCelldroplet-Heart-HEART-1m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A KIF26A PHOSPHO1 JCAD TMEM204 DUSP6 SEZ6L2 USHBP1

1.08e-0619224199da21ce330f3b5661f159cf18d1c3e5ccc11d6dd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO CEMIP2 ATP13A3 PLK3 MRTFA TNC DGKD MACF1 DOT1L

1.08e-0619224198b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE CASZ1 CEMIP2 JCAD ADAMTS1 DUSP6 SORBS1 USHBP1 SMAD7

1.08e-061922419dfa6adc776621f4b51d731b796c0421855b2297c
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 TMEM204 ADAMTS1 NPTN USHBP1 MACF1

1.13e-0619324198084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GID4 STON1 BAZ2B ESPNL PCDHB6 SORBS1 PCDHB16 NPAS4

1.15e-06143241839060dc1d87505a16e2df95140087c731f099570
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 DLC1 JCAD TMEM204 SORBS1 USHBP1

1.18e-061942419f6c9cc362ccdbc7e790f7c8d1c56cab3557c5306
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 JCAD DUSP6 SORBS1 USHBP1 SMAD7

1.23e-06195241952b2bbf12e5f86c493f6634697aeb23a68cc916d
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 JCAD DUSP6 SORBS1 USHBP1 SMAD7

1.23e-061952419e5f14f6015ea5e6fa065f906ad22157e3de15c68
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 JCAD DUSP6 SORBS1 USHBP1 SMAD7

1.23e-0619524195b84fd5be31386eb1d6048bbf28626032361842e
ToppCellfacs-Lung-ENDOMUCIN-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 JCAD DUSP6 SORBS1 USHBP1 SMAD7

1.28e-061962419f6df26ab9eebae893768a4f70a064ce9f60da93c
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NES TRIO DLC1 ATP13A3 ADAMTS1 TNC PCDHB16 NCOR2 MDGA1

1.28e-061962419b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellfacs-Lung-ENDOMUCIN|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 JCAD DUSP6 SORBS1 USHBP1 SMAD7

1.28e-06196241969f03546c42c942ab8ac8746167c8d44d574b4c6
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 TMEM204 ADAMTS1 NPTN USHBP1 MACF1

1.39e-061982419f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

BLM KLK11 CACNB4 MAN1C1 HCN3 CELSR1 ABCB9 DOT1L MDGA1

1.45e-061992419f0c289523957258d16135c04679db379d43d28d9
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CASZ1 KLK11 CACNB4 SHROOM3 DGKD ERN2 ARFGEF3 CELSR1 SHANK2

1.51e-062002419c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RNF130 CASZ1 MAML3 CACNB4 SHROOM3 FIGN ERN2 ARFGEF3 SHANK2

1.51e-0620024190eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

TNK1 GPR162 TOGARAM2 PCDHB2 ERN2 C16orf46 MAPK15 C17orf50

3.51e-0616624184b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SALL2 DRAXIN JCAD PGGHG RASGRF2 TMEM204 NECTIN3 IGDCC4

3.67e-06167241894642b3dae035fedb6e8b9745f440096a4539f3c
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SALL2 DRAXIN JCAD PGGHG RASGRF2 TMEM204 NECTIN3 IGDCC4

3.67e-06167241842b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SALL2 DRAXIN JCAD PGGHG RASGRF2 TMEM204 NECTIN3 IGDCC4

3.67e-061672418ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CEMIP2 CIITA PNRC1 ADAMTS1 KAT6A DGKD SIPA1L1 MACF1

4.01e-061692418c3a6179a64589a370108fea809b157839347759c
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FDXR SEMA3B TADA2A KLK11 PGGHG MIB2 CELSR1 LRCH4

4.01e-061692418665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FDXR SEMA3B TADA2A KLK11 PGGHG MIB2 CELSR1 LRCH4

4.01e-0616924186614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellNS-critical-d_0-4-Myeloid-Monocyte-derived_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KLHDC7B CIITA DRAXIN PADI1 STON1 TAF1C HPS6 LYL1

4.19e-061702418adf73bdc049d508f8873c22539db2ca92052a97b
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPR162 SYNGAP1 SHROOM3 TOGARAM2 C2orf81 CELSR1 MAPK15 SHANK2

4.38e-0617124181854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 RASGRF2 TMEM204 HDAC7 USHBP1

4.57e-061722418a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE2A KIF26A ACE LRG1 FGFR4 RASGRF2 SEZ6L2 HDAC7

4.77e-06173241866488d01e03264fb193285470901c9c4182fbae8
ToppCellfacs-Lung-EPCAM-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 CEMIP2 DLC1 TMEM204 DUSP6 SORBS1 LDB3 USHBP1

5.64e-0617724182433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CEMIP2 JCAD RASGRF2 TMEM204 USHBP1 ZNF408 DISP2

5.64e-0617724188ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHC2 NRXN1 MAN1C1 SEZ6L2 CADPS DISP2 NALF2 NPAS4

5.88e-06178241830ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE HPSE JCAD TMEM204 HDAC7 USHBP1 MACF1 SMAD7

6.38e-061802418dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NES PDE3B ACE JCAD TMEM204 DUSP6 USHBP1 LRRC36

6.38e-061802418544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE2A JCAD RASGRF2 DUSP6 SORBS1 CPNE5 MACF1 TNS1

6.38e-061802418493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE HPSE JCAD TMEM204 HDAC7 USHBP1 MACF1 SMAD7

6.38e-061802418423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN1 KLK11 SHROOM3 ERN2 ARFGEF3 CELSR1 SHANK2 MUC4

6.92e-061822418215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A CEMIP2 DLC1 PHOSPHO1 JCAD TMEM204 ADAMTS1 USHBP1

6.92e-061822418f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NES PDE3B ACE CASZ1 JCAD TMEM204 DUSP6 SORBS1

8.44e-06187241897b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 DLC1 ADAMTS1 DUSP6 USHBP1

8.44e-06187241852ffd4be374e329ac8d321063f061b826d252956
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B EXPH5 NRXN1 KCNC3 BSN CACNB4 ARFGEF3 MAST1

8.44e-0618724181b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA3B FAM135A SHROOM3 DGKD NECTIN3 SHANK2 DOT1L MUC4

8.77e-06188241843a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 JCAD STON1 TMEM204 HDAC7 USHBP1

8.77e-0618824180aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

EXPH5 CASZ1 KCNQ3 SHROOM3 ARFGEF3 CELSR1 SHANK2 MUC4

8.77e-061882418c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE DLC1 JCAD TMEM204 ADAMTS1 VWA1 USHBP1

9.12e-06189241862e46d59d3b89d4566b595c704d8b02f1ea9060b
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE DLC1 JCAD TMEM204 ADAMTS1 VWA1 USHBP1

9.12e-06189241837ce47abd6f96df04d35a4a6189d007bef5ccc94
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE DLC1 JCAD TMEM204 ADAMTS1 VWA1 USHBP1

9.12e-061892418b55324cb365a827d071952709bbf0e8ef8c313de
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A DLC1 JCAD RASGRF2 TMEM204 SORBS1 USHBP1

9.12e-0618924188ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCelldroplet-Lung-LUNG-30m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 DLC1 ADAMTS1 USHBP1 SMAD7

9.12e-06189241825db316f66cee53774bb2b286cc457b37353356c
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

EXPH5 KCNQ3 KLK11 SHROOM3 ERN2 ARFGEF3 SHANK2 MUC4

9.12e-061892418f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PDE2A DLC1 JCAD RASGRF2 TMEM204 SORBS1 USHBP1

9.12e-061892418403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A KIF26A JCAD RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.48e-061902418d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A KIF26A JCAD RASGRF2 TMEM204 SORBS1 USHBP1 TNS1

9.48e-061902418dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

EXPH5 KLK11 SHROOM3 ERN2 ARFGEF3 CELSR1 SHANK2 MUC4

9.85e-0619124183c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellEndothelial-A|World / shred on cell class and cell subclass (v4)

NES ACE CASZ1 CEMIP2 DLC1 DUSP6 SORBS1 USHBP1

1.02e-0519224189919cdc0ce833894525dba429f251ea1b094fbd8
ToppCellfacs-BAT-Fat-3m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES DLC1 JCAD TMEM204 ADAMTS1 SORBS1 USHBP1 TNS1

1.06e-051932418e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 JCAD TMEM204 HDAC7 USHBP1

1.06e-051932418826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 JCAD TMEM204 HDAC7 USHBP1

1.06e-05193241887d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A KIF26A TPBGL CEMIP2 JCAD TMEM204 HDAC7 USHBP1

1.06e-051932418d485634c564b268e344b6a2863c26f6adaec9e38
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ACE CASZ1 CEMIP2 DLC1 TMEM204 ADAMTS1 USHBP1

1.06e-0519324188748af38bfbbbb431ff9d9d5fa75934b5869293a
ToppCellfacs-BAT-Fat-3m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES DLC1 JCAD TMEM204 ADAMTS1 SORBS1 USHBP1 TNS1

1.06e-051932418a211b386fd0fb9da9937361d29d90925a72c9715
ToppCellfacs-BAT-Fat-3m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES DLC1 JCAD TMEM204 ADAMTS1 SORBS1 USHBP1 TNS1

1.06e-0519324183086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCelldroplet-Lung-21m-Endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NES ACE CASZ1 CEMIP2 DLC1 TMEM204 ADAMTS1 USHBP1

1.10e-051942418b45aebbc7641df0bf56d0c2e88821f1daf705449
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACE CASZ1 CEMIP2 DLC1 JCAD ADAMTS1 DUSP6 USHBP1

1.10e-0519424182c78e754cac848fd47172f94e392749eb0ab50d4
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NES ACE CASZ1 CEMIP2 DLC1 TMEM204 ADAMTS1 USHBP1

1.10e-051942418ff076902578997565d72dc40b0b80ae76d6ab2b4
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPR162 CAMTA1 BSN SH2D5 NPTN MAST1 DISP2 ZFR

1.10e-0519424188aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACE CASZ1 CEMIP2 DLC1 JCAD ADAMTS1 DUSP6 USHBP1

1.10e-05194241892a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NES ACE CASZ1 CEMIP2 DLC1 TMEM204 ADAMTS1 USHBP1

1.10e-051942418627432da2e00dc4256f48a6388ce78e7b5e7a51e
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES ACE CASZ1 CEMIP2 DLC1 JCAD TMEM204 USHBP1

1.10e-051942418c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCelldroplet-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NES ACE CASZ1 CEMIP2 DLC1 TMEM204 ADAMTS1 USHBP1

1.10e-051942418fd4548db0f12170b636186e6af90666f7e26c0ad
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES ACE CASZ1 CEMIP2 DLC1 JCAD TMEM204 USHBP1

1.14e-051952418d700e959e060932e3854a9cf294799465efbe18b
ToppCelldroplet-Heart-HEART-1m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A KIF26A PHOSPHO1 JCAD TMEM204 DUSP6 SEZ6L2 USHBP1

1.14e-051952418ec3b7a7257edd806a2364f7dda0ee0996c11f896
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CASZ1 KLK11 SHROOM3 ERN2 ARFGEF3 CELSR1 SHANK2 MUC4

1.14e-051952418e7230a849ea31e6eef9bc6f5468938499450582d
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCMT2 LRG1 DLC1 RASGRF2 ADAMTS1 SORBS1 LDB3 USHBP1

1.19e-0519624189a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 TMEM204 ADAMTS1 HDAC7 USHBP1

1.19e-05196241881900dcc9451ff6606ec940c16b559d73247590e
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCMT2 LRG1 DLC1 RASGRF2 ADAMTS1 SORBS1 LDB3 USHBP1

1.19e-05196241804dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 TMEM204 ADAMTS1 LRRC58 USHBP1

1.23e-051972418d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 TMEM204 ADAMTS1 USHBP1 MACF1

1.23e-051972418a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 TMEM204 ADAMTS1 LRRC58 USHBP1

1.23e-051972418412091994196a06c2779b4c2cfed84be889a5f8d
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A TPBGL CEMIP2 DLC1 TMEM204 ADAMTS1 USHBP1 MACF1

1.23e-051972418deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNC3 KLK11 SHROOM3 ERN2 ARFGEF3 CELSR1 SHANK2 MUC4

1.28e-0519824181408e02e053ad3406229bfe8189da03be6366e81
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNC3 KLK11 SHROOM3 ERN2 ARFGEF3 CELSR1 SHANK2 MUC4

1.28e-051982418af399569c718f5fd971d73a7926768c9311002a3
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA7 TMEM92 PLA2G10 PADI1 KLK11 ERN2 ARFGEF3 MUC4

1.33e-051992418e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCellKidney-Endothelial|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

NES PDE2A DLC1 JCAD TMEM204 VWA1 USHBP1 LYL1

1.33e-051992418b543f0686522df43737e9ffa5c9733e42b8a9f4d
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CEMIP2 DLC1 SEMA3B JCAD RASGRF2 TMEM204 SORBS1 TNS1

1.37e-052002418032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CEMIP2 DLC1 SEMA3B JCAD RASGRF2 TMEM204 SORBS1 TNS1

1.37e-05200241868fce28690246895fd33354b30960ebcc31aa4cc
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CASZ1 MAML3 CACNB4 SHROOM3 ERN2 ARFGEF3 CELSR1 SHANK2

1.37e-052002418d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CEMIP2 DLC1 SEMA3B JCAD RASGRF2 TMEM204 SORBS1 TNS1

1.37e-052002418878bbbe32e3602723aa14ef32877ab2453b8c6e5
DrugVigabatrin [60643-86-9]; Up 200; 31uM; MCF7; HT_HG-U133A

PDE3B TRIO PIDD1 ABCA7 DLC1 AP5Z1 ATP13A3 PLK3 MRTFA CNTN1 DUSP6 ZNF79

1.45e-06199240125415_UP
DrugU-62066 [87151-85-7]; Down 200; 1uM; MCF7; HT_HG-U133A

ABL2 ABCA7 DLC1 ALK PADI1 JCAD STON1 DUSP6 HDAC7 NCOR2 ABCB9 TSKS

1.45e-06199240124375_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; HL60; HG-U133A

INHA PIDD1 PRDM10 AP5Z1 PADI1 MRTFA KLK11 SHANK2 ZNF408 ZFR ZNF79 TNS1

1.52e-0620024012409_DN
DrugFamotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

NES ARHGEF17 DLC1 AP5Z1 PADI1 MRTFA CNTN1 NCOR2 ABCB9 NEURL1 NALF2

7.92e-06196240115011_UP
DrugPipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A

ITGAM ACE AP5Z1 TADA2A ALK MRTFA KAT6A SORBS1 NECTIN3 NEURL1 LYL1

7.92e-06196240116821_UP
DrugSulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A

CHAT DLC1 KCNQ3 TSC22D4 MRTFA SUPT20H PGGHG TNC HDAC7 ABCB9 CSPP1

8.31e-06197240111693_UP
DiseaseAlzheimer disease, educational attainment

ABCA7 NRXN1 BSN MAML3 IGDCC4 ARSA ABCB9 EGR2 MEIOSIN

1.39e-042472289EFO_0011015, MONDO_0004975
DiseaseFamilial Testotoxicosis

INHA LHCGR

1.77e-0432282C0342549
DiseaseRhabdomyosarcoma

FGFR4 ALK DICER1

1.93e-04152283C0035412
Diseasefocal segmental glomerulosclerosis

FGFR4 IPO4 PPCS

2.37e-04162283EFO_0004236
Diseaselung carcinoma (is_marker_for)

ACE MUC4

5.85e-0452282DOID:3905 (is_marker_for)
Diseasemental or behavioural disorder, attempted suicide

JCAD SORBS1

5.85e-0452282EFO_0000677, EFO_0004321
Diseasevisual epilepsy (biomarker_via_orthology)

GLUD2 DRD3 ADAMTS1 DUSP6 NEURL1

6.80e-04902285DOID:11832 (biomarker_via_orthology)
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

AARS2 MTMR3 FGD3

8.17e-04242283DOID:10595 (implicated_via_orthology)
Diseasefear of pain measurement

TRMT12 NEURL1

8.74e-0462282EFO_0008330
DiseaseAutistic Disorder

ACE SYNGAP1 NRXN1 DRD3 TAF1C SEZ6L2 SHANK2 EGR2

1.01e-032612288C0004352
Diseasebrain ischemia (biomarker_via_orthology)

NES ITGAM GLUD2 ADAMTS1 DUSP6

1.20e-031022285DOID:2316 (biomarker_via_orthology)
Diseasesystemic lupus erythematosus

PCNX3 ITGAM SYNGAP1 CIITA LRRC56 SHROOM3 STON1 PHRF1 HECTD4 ARHGAP9 MED1 CPNE5 SEZ6L2 DOT1L NEURL4

1.48e-0379922815MONDO_0007915
Diseaseresting heart rate, chronic obstructive pulmonary disease

CASZ1 STON1 TNS1

1.58e-03302283EFO_0000341, EFO_0004351
DiseaseJuvenile Myoclonic Epilepsy

KCNQ3 CACNB4

1.61e-0382282C0270853
Diseasemyocardial infarction

GID4 PSRC1 JCAD SHROOM3 STON1 HECTD4 FIGN TNS1 SMAD7

1.70e-033502289EFO_0000612
Diseaseeosinophilic esophagitis

NRXN1 SHROOM3 ESPNL TOGARAM2 URGCP SHANK2

1.73e-031632286EFO_0004232
DiseaseMalignant neoplasm of breast

PDE2A ADAT3 STXBP4 HPSE MTMR3 NLRC5 TSC22D4 ALK RASGRF2 ADAMTS1 SHMT1 SORBS1 HDAC7 LHCGR KMT2D SIPA1L1 MACF1 TNS1

1.82e-03107422818C0006142
Disease5,6-dihydrothymine measurement

CIITA KIAA1614

2.06e-0392282EFO_0800638
Diseasepulse pressure measurement, alcohol drinking

CASZ1 JCAD C1orf167 FIGN

2.14e-03702284EFO_0004329, EFO_0005763
Diseasediastolic blood pressure, alcohol drinking

CASZ1 HECTD4 TOGARAM2 C1orf167 FIGN

2.27e-031182285EFO_0004329, EFO_0006336
DiseaseKartagener Syndrome

DNAAF5 LRRC56 DNAH1

2.48e-03352283C0022521
Diseasedifferentiated thyroid carcinoma

KCNQ3 STON1 SOWAHB

2.48e-03352283EFO_1002017
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

DNAAF5 LRRC56 DNAH1

2.48e-03352283C4551906
DiseasePolynesian Bronchiectasis

DNAAF5 LRRC56 DNAH1

2.48e-03352283C4317124
DiseasePR domain zinc finger protein 1 measurement

BSN LBP

3.12e-03112282EFO_0801904
Diseaseinterleukin 10 measurement

MRPL37 AARS2 SHROOM3 SUPT20H

3.17e-03782284EFO_0004750
Diseasewaist-hip ratio

BDH1 DLC1 CIITA SEMA3B FGFR4 MAML3 JCAD NAT14 DUSP6 HECTD4 SHMT1 FIGN DNAJA3 LHCGR ABCB9 CADPS DOT1L RSBN1L LRRC36

3.27e-03122622819EFO_0004343
Diseasechronotype measurement

CEMIP2 SYNGAP1 NRXN1 CAMTA1 BSN DRD3 STON1 ARHGAP9 TARS2 DNAH1 LHCGR KMT2D AADAT MDGA1 NALF2

3.77e-0388222815EFO_0008328
DiseaseSchizophrenia

CHAT ITGAM ACE SYNGAP1 NRXN1 KCNQ3 ALK DRD3 SHMT1 DICER1 NPTN EGR2 GPR153 MDGA1 NPAS4

3.81e-0388322815C0036341
Diseaseresponse to antihypertensive drug

ALK HECTD4 LDB3

3.91e-03412283EFO_0005405
Diseaseviral load

RNF130 PRDM10 ALK ADAMTS1 CADPS

4.18e-031362285EFO_0010125
Diseasecholangiocarcinoma (biomarker_via_orthology)

TNC MUC4

4.38e-03132282DOID:4947 (biomarker_via_orthology)
Diseaseintermediate coronary syndrome (is_marker_for)

ITGAM ACE

4.38e-03132282DOID:8805 (is_marker_for)
Diseaseresponse to ketamine, dissociation measurement

RASGRF2 TOGARAM2

4.38e-03132282EFO_0009748, EFO_0009750
Diseasebody surface area

PDE2A DLC1 MTMR3 FGFR4 LMF1 DICER1 NCOR2 MACF1 DOT1L RSBN1L SOWAHB SMAD7

4.52e-0364322812EFO_0022196
DiseaseLeft ventricular noncompaction

MIB2 LDB3

5.09e-03142282C1960469
Diseaseextrinsic allergic alveolitis (is_marker_for)

ACE TNC

5.09e-03142282DOID:841 (is_marker_for)
Diseaseparental longevity

AP5Z1 BSN GPANK1 PSRC1 JCAD SHROOM3 ADAMTS1 ATP13A1 HECTD4 SMAD7

5.33e-0349422810EFO_0007796
DiseaseAdenocarcinoma of lung (disorder)

TNK1 FGFR4 ALK SHMT1 IPO4 DOT1L

5.47e-032062286C0152013
DiseasePrimary Ciliary Dyskinesia

DNAAF5 LRRC56 DNAH1

5.75e-03472283C4551720
DiseaseNephrosis

NES HPSE

5.84e-03152282C0027720
DiseaseMale sterility

ACE LHCGR KMT2D

6.10e-03482283C0917731
DiseaseMale infertility

ACE LHCGR KMT2D

6.10e-03482283C0021364
DiseaseSubfertility, Male

ACE LHCGR KMT2D

6.10e-03482283C0848676
Diseaseplatelet component distribution width

JMY BRD8 DLC1 ATP13A3 TSC22D4 CAMTA1 FGD3 JCAD SUPT20H HDAC7 NCOR2 MACF1 SIGLEC1

6.16e-0375522813EFO_0007984
Diseasepancreatitis

JCAD HECTD4

6.64e-03162282EFO_0000278
Diseasemigraine disorder

MRPL37 CASZ1 CAMTA1 JCAD SPATA19 SORBS1 NCOR2 MACF1

6.85e-033572288MONDO_0005277
DiseaseDepressive disorder

CHAT ACE HPSE NRXN1 ALK DRD3 DUSP6

7.46e-032892287C0011581
Diseasethyroxine measurement, triiodothyronine measurement

STON1 ABCB9

7.49e-03172282EFO_0005130, EFO_0008392

Protein segments in the cluster

PeptideGeneStartEntry
LGTQAGPALPRLEKT

USHBP1

466

Q8N6Y0
LAGPASGPRSLAELL

ADAT3

96

Q96EY9
SSGLRIGFLTGPKPL

AADAT

266

Q8N5Z0
GSLPSLSLESPLLGA

MLLT6

536

P55198
SPRSLEEPGLLSGAR

BAHCC1

1141

Q9P281
ASPGPRLGLALKDTT

C1orf167

266

Q5SNV9
LPRTLASLALNLPGG

ARHGEF18

106

Q6ZSZ5
AISIPDSLGRLPLGI

CAMTA1

1136

Q9Y6Y1
LDLTRNALTGLPPGL

LRG1

121

P02750
SLSPTLLALGLPRDG

LINC00696

111

Q6ZRV3
GATALPLRTPSGDLA

ABL2

856

P42684
PLPDSGRVSFLGLDL

ACE

1236

P12821
GARRPLLLGSTSFIP

BDH1

26

Q02338
ASGAPTLSRLLEAGP

BRD8

261

Q9H0E9
HIRSSGALGLPPSLL

CASZ1

696

Q86V15
GALGLPPSLLGAKDT

CASZ1

701

Q86V15
GRLSFLGTRLTPPDA

CIITA

831

P33076
RPPSGLISGALLFSV

ATP13A3

996

Q9H7F0
ELPRIPGLVLSGSTF

BAZ2B

1076

Q9UIF8
LLQDLKAGLLPSGPR

FDXR

421

P22570
SIDGSIVLPLARGSP

ATP13A1

786

Q9HD20
SGPALLAGLVSLDLP

FGFR4

441

P22455
ALLLSLLPTPGLGTQ

ADAM11

11

O75078
ASTRPTILLLPGLTG

ABHD3

136

Q8WU67
GNCLKGSRPLLSFDP

BRIX1

156

Q8TDN6
LAPVRSGALRSGPSL

SMDT1

11

Q9H4I9
LRALGREPASPGLSS

CCDC142

186

Q17RM4
LGSTRSLPQLKPALG

AMTN

11

Q6UX39
LLLLGRSDSLYPAPG

AP5Z1

581

O43299
SLSIKAQDGGRPPLI

CELSR1

531

Q9NYQ6
RPLSPGALQLAGEKS

DOT1L

831

Q8TEK3
SSRTLGPNPGLILQA

DICER1

1286

Q9UPY3
LESKPPSRGGALLFC

DHX30

521

Q7L2E3
TPLLGRNLGSTALSP

CACNB4

411

O00305
AGLLGARLPDFSKPL

DISP2

186

A7MBM2
LPAGGRVAASLLSPV

ABCA7

681

Q8IZY2
RPLLTPGGSRASLAL

CECR9

51

P0C854
GLSIPGPLTSRALLV

C16orf46

196

Q6P387
RALLPPAGTGQTLLL

IGDCC4

1091

Q8TDY8
PLGRILIGSSFPKSG

PADI1

426

Q9ULC6
GSRSFGPVPTLLLLA

ADAMTS1

26

Q9UHI8
GSLQASPRGLLPGLL

EDC4

671

Q6P2E9
PLTPLSTIRNFTLGG

EGR2

261

P11161
SLGLEPLRTSGISPL

RNF130

351

Q86XS8
PGGGRLLLSTSLDAK

INTS3

31

Q68E01
TIAKLSIRPPGGLES

PTPN23

1501

Q9H3S7
RLTLTALDGGSPPRS

PCDHB2

211

Q9Y5E7
LPPDIGTLGSLRQLD

LRCH4

151

O75427
DSNLLGSLSPKTGLP

ARHGEF17

756

Q96PE2
STFLRVLSGKPPLEG

ARL10

91

Q8N8L6
PLPLGALAQGGTLSI

MDGA1

281

Q8NFP4
KEVLGSAPSGARLSP

CADPS

21

Q9ULU8
PSSFLLLGIPGLETL

OR52E2

11

Q8NGJ4
LFKPATGFPLGSSLR

MUC4

4341

Q99102
GGDKNRLLSPRPSLL

NCOR2

931

Q9Y618
TALPRSILLFGPRGT

FIGN

516

Q5HY92
DTEPGRKSGLTLLGP

ESPNL

936

Q6ZVH7
AGPAGLLELNPTSLR

KLHL34

166

Q8N239
SALRPVPGQGLSLSI

LBP

91

P18428
GPTAGLTRLSLAYLP

LHCGR

46

P22888
SLLGDPRLRSPGSKG

JMY

121

Q8N9B5
GARDLLGPKALPGSS

LDB3

176

O75112
PGSTPLRDRLAALGK

NCKAP5L

656

Q9HCH0
TPGLLEDLSKNGRLP

MAML3

236

Q96JK9
LGVPISSPGFKLLLR

GPANK1

251

O95872
SILPSLLGLLSFPRN

JAGN1

81

Q8N5M9
ATLAPIGSRGPQLLL

NUDT22

66

Q9BRQ3
LGLSPRRLSLGSPES

GPR162

531

Q16538
LSLVKPSGRGAAPSL

MAPK15

441

Q8TD08
RDLKPGNILITGPDS

ERN2

636

Q76MJ5
SSQLLPGAKLGGPSR

JCAD

701

Q9P266
RGLSAPDLRSVGLTP

JCAD

1041

Q9P266
TPQGIGLLAKTPLSR

KCNQ3

81

O43525
LPSSPGLLRSLLERG

KDM5D

881

Q9BY66
RVLGGLSSPLRLLPA

KIAA1614

571

Q5VZ46
QTKRLLEGSLGEPTP

BSN

516

Q9UPA5
GLSSPELKVRPAGAS

FAM135A

451

Q9P2D6
RPPALLLLAAASSGL

NAT14

41

Q8WUY8
LSGLFSTPLNPLLGS

PCNX3

1281

Q9H6A9
PLVLGGRLAPLGFSS

PNRC1

11

Q12796
SQAPTLLLLGGLPSS

FOXO4

391

P98177
PSLGRVLPGSSVLFL

ISOC2

6

Q96AB3
GNRTTPLRTLLLSPG

LRRC36

441

Q1X8D7
GLGFSDLPGKPLARL

PDE2A

121

O00408
SLGSLPSALRPLLSG

PDE3B

236

Q13370
GLGPSKRILGSLLSD

PEX5

451

P50542
PSTLGVSLPIGERLS

CSPP1

156

Q1MSJ5
LSLRPSALDSGPRGA

GPR153

461

Q6NV75
LLGFLGATLSAPLIP

ODAM

6

A1E959
PVPDLLGSILSGQSL

PHRF1

501

Q9P1Y6
GRRLGSLLPVLSPTS

NES

341

P48681
GLTAAKEPGARSSPL

KLK11

16

Q9UBX7
GSTSVRKGPLPFLIN

EXPH5

1106

Q8NEV8
KLVSGPGTTLRDPCL

KIF26A

86

Q9ULI4
VSNKPALLPVSGGSR

NALF2

411

O75949
LNSLLAGGKTSLGPP

MSLNL

216

Q96KJ4
FDLSPLLLGTGKSPR

ARSA

356

P15289
SSSLGKLQALPVGPR

FGD3

26

Q5JSP0
ARLAPGSGPITLLLR

PGGHG

121

Q32M88
GSDPLATLQTPLGRL

PRDM10

116

Q9NQV6
GVRLSLGPLSPEKLE

PSRC1

61

Q6PGN9
RGALPPDSLSTRKGL

PSRC1

301

Q6PGN9
GGLPPELRAAALKLT

NRXN1

156

Q9ULB1
LLLLLPGPGSGEASR

PLA2G10

21

O15496
RKGSGSERLPPSGLL

HCN3

731

Q9P1Z3
QPLLSSSEGRPFRLG

HECTD4

1546

Q9Y4D8
GGARLSTKDPLPTIA

MRPL37

226

Q9BZE1
LGLSPSLFSSPGKLL

MEIOSIN

361

C9JSJ3
LRLGLTALDPASLAP

NEURL2

81

Q9BR09
GSPKLRTLARGLSPA

HPSE

76

Q9Y251
LVSLPRALGSGFPHL

LRRC58

56

Q96CX6
PGLPELRKIDLSGNS

NLRC5

1631

Q86WI3
LGRQESPLSLGADPL

MAST1

1331

Q9Y2H9
GGSSPETLPSLLKRQ

MACF1

3911

Q9UPN3
PSGASGNLPLLLSLL

MEI1

901

Q5TIA1
RPGLSLPATLLGSRA

GID4

51

Q8IVV7
RPSGPALSGLLSLEA

PPCS

106

Q9HAB8
PQLRLTLTALDGGSP

PCDHB16

206

Q9NRJ7
AGSPEKPLSDLGRLS

KAT6A

676

Q92794
PLGGLEPLDSNLSLS

NPAS4

661

Q8IUM7
LSDLGQPRKSPLTGT

DNAH1

71

Q9P2D7
ELSLAGALAPGTPAR

DRAXIN

21

Q8NBI3
RGGSKSLLPDFLQTP

BLM

101

P54132
PPGSIKALSRLADLG

C5orf24

141

Q7Z6I8
PTLGLKTDAIPGRLN

MT-CO2

166

P00403
GLSPLSPTVELRLQG

CEP97

411

Q8IW35
SLSLKAGGGDLLLPP

ARFGEF3

1976

Q5TH69
SGPKLLSGLSRDRDP

CCDC166

401

P0CW27
KISGAPTLSPSLLGL

CNTN1

991

Q12860
LGLLTKPGTLLPTDR

CEMIP2

621

Q9UHN6
LGPLALLGGLTAPTD

C17orf50

96

Q8WW18
KISSLCGLGFPSRDP

BPESC1

81

Q9GZL8
RLGEKLLPAFNTPTG

MAN1C1

286

Q9NR34
GTLRPPLLQLSTLGT

LYL1

81

P12980
PGSRDGLPALNTKIL

DGKD

706

Q16760
NSSEPLLGLLALSPG

INHA

146

P05111
LGSTGVLSPFILTLP

KLHDC7B

571

Q96G42
GPALLFPTLNLGLSS

C2orf81

416

A6NN90
LSRLLPGLEADSKPG

DNAAF5

31

Q86Y56
RFSGAGASTPQPLLL

ESRG

206

Q1W209
PRGSTGDTVLLPLAQ

HDAC7

461

Q8WUI4
RALDAGLALGPSSPL

HPS6

651

Q86YV9
GLALGPSSPLLRSEI

HPS6

656

Q86YV9
GPRALLTLRPGVSLT

DNAJA3

56

Q96EY1
PLPVLGLGGLRISSD

DUSP6

161

Q16828
ARGLEATASPGLLKP

SALL2

336

Q9Y467
SCGTLTLKPPGRLAE

IPO4

781

Q8TEX9
AKALLPSRAGPAALG

GLUD2

6

P49448
TASILSCRPLKGEPG

NEURL4

1441

Q96JN8
PGSRLEKPLTIGAFS

CPNE5

126

Q9HCH3
LSNGRLSTSLKLGPL

DRD3

301

P35462
LSTSLKLGPLQPRGV

DRD3

306

P35462
PLPDGRSLQGTLVSK

MED1

381

Q15648
KAELGLAPSALPAGR

FEZF2

136

Q8TBJ5
GLSVLLSSLQVPPRG

MTMR3

771

Q13615
LPLPSGITGLSLDRS

PIDD1

536

Q9HB75
TASALPGLGPREKVS

OSBPL7

171

Q9BZF2
PGPLQLLSRLQASGL

MIB2

726

Q96AX9
QLRLTLIALDGGSPP

PCDHB6

206

Q9Y5E3
PGLLLGATLPTSGVL

OTOG

1886

Q6ZRI0
LRPSGLRLGTPALTS

SHMT1

396

P34896
TSAFGIELLPRKGPS

RNF139

111

Q8WU17
LSLLEAPGGQPRKSL

HIC2

316

Q96JB3
FGKLQLSSRDPPGSL

RSBN1L

26

Q6PCB5
RLALSTRPSGFLGDP

TARS2

491

Q9BW92
LRGLAPSAVPGLSKT

REXO1

871

Q8N1G1
LNPELSAGPITGLRD

TRIM49

266

P0CI25
LGLGLSRPFLPGATV

TP53AIP1

86

Q9HCN2
SRLELASLGLGAPTP

TSC22D4

126

Q9Y3Q8
NSGRRSAPPLNLTGL

TADA2A

356

O75478
LPLRGSGTLSVPTRL

TOGARAM2

401

Q6ZUX3
SLLVRGGPLPEGLLS

LRRC56

296

Q8IYG6
PPGLFDGLLALRSLS

LRTM2

156

Q8N967
LLGSAVGDPDPTRLI

NTN5

431

Q8WTR8
PLLPGSTFALRIGTR

PLAC8L1

111

A1L4L8
TGQIPLDLSRGLSSP

RASGRF2

781

O14827
SLRPALFLTGPLGLS

TAF1C

6

Q15572
SLTGTQALPPLFSLG

GANAB

381

Q14697
EVPLKPLSSSGGLVR

SH2D5

166

Q6ZV89
LTLNGGPLVRSKPSE

MRAP

146

Q8TCY5
SEADPAPLLGGRLLL

RNF215

81

Q9Y6U7
RGPTPTKLSDFLITG

SIPA1L1

236

O43166
LGAPSTPGRISLRIS

SHROOM3

1476

Q8TF72
PIGSFLGSLSLLPAT

ACAT1

51

P24752
SPDLGSPVSRTLGLL

SEZ6L2

186

Q6UXD5
SLVGTPLSAFGNLRP

ITGAM

736

P11215
PLGRNGRSIPATLAL

STXBP4

466

Q6ZWJ1
PCTNRGLPLLKTDFG

DLC1

261

Q96QB1
GTAPSPRVDAGLSLK

SOWAHB

536

A6NEL2
LELSSGGPVLSLAPL

MRTFA

891

Q969V6
LSLGVPASRVLSFGP

AARS2

191

Q5JTZ9
TGRLLDPSSPLALAL

SHANK2

1206

Q9UPX8
RLEPGLSSPFSDLLG

THAP7

166

Q9BT49
LLSTVRPGTQALEPG

ABCB9

136

Q9NP78
ATGRLPGASLLLEPS

ALK

1546

Q9UM73
RLPPIGLLTSDGRSE

CHAT

346

P28329
RSLGVLPFTLNSGSP

NCAPD3

1371

P42695
PLLSPSRGFLLCKTG

COA6

6

Q5JTJ3
LARKGVGLPFLPITS

SPATA19

11

Q7Z5L4
LNKGRSPATGAALTP

ZNF767P

121

Q75MW2
LLLGAGRTPQPDSAL

PPOX

201

P50336
FPGLASELLLTGLPL

URGCP

646

Q8TCY9
VAPLPLGTGALRASL

VWA1

61

Q6PCB0
LAGLPTSDPGRLITD

PLK3

41

Q9H4B4
VPGLAPTLLFSLLAG

TMEM92

6

Q6UXU6
LAPGGLSDSQLLLEP

SMAD7

241

O15105
PSIQTLAPAGGTLLL

TMEM256

91

Q8N2U0
FLLALGSRSRPGDSP

USP43

31

Q70EL4
PLGLSASPRLAAREG

USP43

371

Q70EL4
TDGRLFSLKPTSGPV

VNN1

456

O95497
QSLRSLLGEGPLERP

TEP1

1471

Q99973
LGSTILAERGIPSLP

NEURL1

446

O76050
KLNLPGLREFPSGSS

STON1

41

Q9Y6Q2
SLTAALGLRPAPAGR

SYNGAP1

876

Q96PV0
LRTSLLSADGGPRDP

SAPCD2

91

Q86UD0
EPPLGGLVDSRLALT

SHC2

346

P98077
GARSSPKQPLAEGLL

STOML1

281

Q9UBI4
ISVPKGSRPSAEGLL

SEMA3B

461

Q13214
LNPELSAGPITGLRD

TRIM49C

266

P0CI26
SLPRGLALGPSLAKE

ZNF408

56

Q9H9D4
IPLQGLSGLKRPSSS

SORBS1

691

Q9BX66
GVPFGLKNTSSLRPL

SUPT20H

606

Q8NEM7
SLRPLNLLQLPGGSL

SUPT20H

616

Q8NEM7
SPELALTIALNPGGR

TNS1

926

Q9HBL0
ALSLLLVSGSLLPGP

NPTN

11

Q9Y639
LTVPGGLRSTDLPGL

TNC

1211

P24821
LSNPSGPDARGLLAL

PHOSPHO1

146

Q8TCT1
SLLKPFQEGPSGRSL

ARHGAP9

151

Q9BRR9
PLELRLSGSGPAELS

ARHGAP9

461

Q9BRR9
SLRSELEGLGPLKPI

TSKS

406

Q9UJT2
SPSGRNILPGELVTL

SIGLEC1

246

Q9BZZ2
PGRLSRALSLGTIPS

TMEM201

446

Q5SNT2
RGSSPILSEGSLPAL

ZNF469

3466

Q96JG9
SSGIILKGSPGLLDP

ZFR

976

Q96KR1
GSGPALRLAVTSLIP

ZMYM6

1301

O95789
RSLESVLSLGPRPTG

TNK1

501

Q13470
LLGLAGNALSRLPPA

TPBGL

176

P0DKB5
TFLLGLVGLPLLSPD

TMEM204

116

Q9BSN7
LLYGPPGTGKTLLAR

PSMC6

171

P62333
PDGTRTPAVTLLLGD

TRMT12

181

Q53H54
LNPELSAGPITGLRD

TRIM49B

266

A6NDI0
LVLGGRLSPVSPALG

LCMT2

431

O60294
SRSLVLLGLPVSQPG

ZNF79

71

Q15937
GPFPTGSLLDLRFLS

WBP1

106

Q96G27
GGGLSKINTPLLTPL

USP1

546

O94782
DARASLGTLPLGKPR

TRIO

2436

O75962
RTCLPSKPLLGLGSS

XKR8

186

Q9H6D3
ASVPSRPGQLSLLEG

GARIN5B

736

Q8N5Q1
LRTLPGTRLAGLTEP

KCNC3

106

Q14003
PGNLALRSLGPDSRL

KMT2D

3701

O14686
SPGALGPTLLLTGKE

KMT2D

4011

O14686
LFPSGPGSLKDRVLQ

LMF1

331

Q96S06
SASLLGAGLLLQPPT

NECTIN3

21

Q9NQS3