Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoAccessory carpal bones

FLNA FLNB

2.91e-052282HP:0004232
HumanPhenoBipartite calcaneus

FLNA FLNB

2.91e-052282HP:0008127
DomainIg_E-set

FLNA FLNB FLNC NFATC3 RELA EXOC2 PLXNA2

2.59e-07104787IPR014756
DomainTIG

NFATC3 RELA EXOC2 PLXNA2

8.13e-0631784PF01833
DomainIG_FLMN

FLNA FLNB FLNC

8.23e-0610783SM00557
DomainIPT

NFATC3 RELA EXOC2 PLXNA2

9.26e-0632784IPR002909
DomainFilamin

FLNA FLNB FLNC

1.13e-0511783PF00630
DomainFILAMIN_REPEAT

FLNA FLNB FLNC

1.13e-0511783PS50194
DomainFilamin/ABP280_rpt

FLNA FLNB FLNC

1.13e-0511783IPR001298
DomainFilamin/ABP280_repeat-like

FLNA FLNB FLNC

1.13e-0511783IPR017868
DomainActinin_actin-bd_CS

FLNA FLNB FLNC

1.17e-0423783IPR001589
DomainACTININ_2

FLNA FLNB FLNC

1.17e-0423783PS00020
DomainACTININ_1

FLNA FLNB FLNC

1.17e-0423783PS00019
DomainIg-like_fold

FLNA FLNB FLNC COL12A1 HMCN2 NFATC3 ROR2 RELA EXOC2 IL1RL2 PLXNA2

1.61e-047067811IPR013783
DomainFAD_binding_6

CYB5R3 CYB5R1

1.71e-045782PF00970
DomainGroucho_enhance

TLE1 TLE4

1.71e-045782IPR009146
DomainNADH-Cyt_B5_reductase

CYB5R3 CYB5R1

1.71e-045782IPR001834
DomainOxRdtase_FAD-bd_dom

CYB5R3 CYB5R1

1.71e-045782IPR008333
DomainTLE_N

TLE1 TLE4

1.71e-045782PF03920
DomainGroucho/TLE_N

TLE1 TLE4

1.71e-045782IPR005617
DomainIPT

NFATC3 RELA PLXNA2

1.91e-0427783SM00429
Domain-

FLNA FLNB FLNC COL12A1 NFATC3 ROR2 RELA EXOC2 IL1RL2 PLXNA2

4.24e-0466378102.60.40.10
DomainRHD_dimer

NFATC3 RELA

7.58e-0410782IPR032397
DomainRHD_dimer

NFATC3 RELA

7.58e-0410782PF16179
DomainNFkB/Dor

NFATC3 RELA

7.58e-0410782IPR000451
DomainREL_1

NFATC3 RELA

7.58e-0410782PS01204
DomainRHD_DNA_bind_dom

NFATC3 RELA

7.58e-0410782IPR011539
DomainRHD_DNA_bind

NFATC3 RELA

7.58e-0410782PF00554
DomainFlavoprot_Pyr_Nucl_cyt_Rdtase

CYB5R3 CYB5R1

7.58e-0410782IPR001709
DomainREL_2

NFATC3 RELA

7.58e-0410782PS50254
Domain-

NFATC3 RELA

7.58e-04107822.60.40.340
DomainOxRdtase_FAD/NAD-bd

CYB5R3 CYB5R1

1.11e-0312782IPR001433
DomainNAD_binding_1

CYB5R3 CYB5R1

1.11e-0312782PF00175
DomainCH

FLNA FLNB FLNC

2.54e-0365783SM00033
DomainDSRM

ILF3 ADAR

2.81e-0319782SM00358
DomainFd_Rdtase_FAD-bd

CYB5R3 CYB5R1

2.81e-0319782IPR017927
DomainFAD_FR

CYB5R3 CYB5R1

2.81e-0319782PS51384
DomainRiboflavin_synthase-like_b-brl

CYB5R3 CYB5R1

2.81e-0319782IPR017938
Domaindsrm

ILF3 ADAR

3.12e-0320782PF00035
DomainCH

FLNA FLNB FLNC

3.14e-0370783PF00307
Domain-

FLNA FLNB FLNC

3.27e-03717831.10.418.10
DomainDS_RBD

ILF3 ADAR

3.43e-0321782PS50137
DomainTIR

TLR3 IL1RL2

3.43e-0321782SM00255
DomainCH

FLNA FLNB FLNC

3.53e-0373783PS50021
DomainTIR

TLR3 IL1RL2

3.77e-0322782PF01582
DomainCH-domain

FLNA FLNB FLNC

3.81e-0375783IPR001715
Domain-

TLR3 IL1RL2

4.12e-03237823.40.50.10140
DomainTIR

TLR3 IL1RL2

4.48e-0324782PS50104
DomainTIR_dom

TLR3 IL1RL2

4.85e-0325782IPR000157
DomainVWFA

CACNA2D1 COL12A1 HMCN2

4.90e-0382783PS50234
DomainVWA

CACNA2D1 COL12A1 HMCN2

5.24e-0384783SM00327
Domain-

ILF3 ADAR

5.65e-03277823.30.160.20
DomaindsRBD_dom

ILF3 ADAR

6.07e-0328782IPR014720
DomainSema

SEMA5B PLXNA2

7.40e-0331782SM00630
DomainSemap_dom

SEMA5B PLXNA2

7.40e-0331782IPR001627
DomainSema

SEMA5B PLXNA2

7.40e-0331782PF01403
DomainSEMA

SEMA5B PLXNA2

7.40e-0331782PS51004
DomainKinase-like_dom

CDK17 ERBB3 LATS2 PSKH1 ROR2 FN3KRP MAP2K5

7.46e-03542787IPR011009
DomainPSI

SEMA5B PLXNA2

7.87e-0332782PF01437
DomainPlexin_repeat

SEMA5B PLXNA2

7.87e-0332782IPR002165
DomainVWF_A

CACNA2D1 COL12A1 HMCN2

8.25e-0399783IPR002035
PathwayWP_NPHP1_DELETION_SYNDROME

FLNA FLNB FLNC

1.65e-0511673M48099
PathwayWP_EBOLA_VIRUS_INFECTION_IN_HOST

NPC1 FLNA FLNB FLNC RELA ADAM17

3.30e-05129676M39693
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNA FLNB FLNC

1.09e-08378312393796
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNA FLNB FLNC

1.09e-08378311153914
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNA FLNB FLNC

1.09e-08378311252955
Pubmed

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.

FLNA FLNB FLNC

4.33e-08478311739414
Pubmed

Structural interaction and functional regulation of polycystin-2 by filamin.

FLNA FLNB FLNC

4.33e-08478322802962
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FLNA FLNB ILF3 IPO7 CLPB FN3KRP SMC6 CYB5R3 IDE CDC5L RFC3 ECPAS ADAR RCC2 TMEM117 RPL15

9.06e-081425781630948266
Pubmed

Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.

FLNA FLNB FLNC

1.08e-07578312006559
Pubmed

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

FLNA FLNB FLNC

1.08e-07578317360453
Pubmed

HIV infection of T cells: actin-in and actin-out.

FLNA FLNB FLNC

1.08e-07578319366992
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

NPC1 FLNA FLNB FLNC ILF3 IPO7 CYB5R3 ADAR RCC2 RPL15

1.34e-07484781031995728
Pubmed

The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.

FLNA FLNB FLNC

3.77e-07778316076904
Pubmed

MEKK4 signaling regulates filamin expression and neuronal migration.

FLNA FLNB FLNC

6.03e-07878317145501
Pubmed

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

FLNA FLNB FLNC

9.03e-07978311807098
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NPC1 CLIP4 HDAC9 FLNB USP13 ERBB3 HIVEP2 MAN1A2 CLPB RSPH1 GPSM2 TAF1 LRP1B RPL15

9.25e-071285781435914814
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA FLNB ILF3 CDC5L ADAR PRDM16 RCC2

1.00e-0623478736243803
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

FLNA FLNB FLNC ILF3 IPO7 FN3KRP CDC5L ECPAS RPL15

1.68e-0649478926831064
Pubmed

Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.

FLNA FLNB FLNC

1.77e-061178336579465
Pubmed

Defining the membrane proteome of NK cells.

NPC1 FLNA SCCPDH MAN1A2 ILF3 IPO7 CYB5R3 ADAM17 EXOC2 CDC5L ECPAS ADAR CYB5R1

1.88e-061168781319946888
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

FLNA FLNC ILF3 IPO7 FN3KRP SMC6 CDC5L RFC3 ECPAS RCC2 RPL15

1.90e-06809781132129710
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

FLNA ILF3 IPO7 CLPB CDC5L RFC3 ECPAS ADAR RCC2 WDR44

2.03e-06653781033742100
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

FLNA FLNB FLNC COL8A1 ILF3 IPO7 CLPB PKP4 FN3KRP RCC2 RPL15

2.85e-06844781125963833
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNA FLNB TLE1 TLE4 TET1 CYB5R3 TAF1 ECPAS

4.58e-0641878834709266
Pubmed

Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.

FLNA FLNB

4.97e-06278217635842
Pubmed

Combinatorial expression patterns of individual TLE proteins during cell determination and differentiation suggest non-redundant functions for mammalian homologs of Drosophila Groucho.

TLE1 TLE4

4.97e-0627829572356
Pubmed

A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.

FLNB FLNC

4.97e-0627829694715
Pubmed

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.

FLNA FLNC

4.97e-0627827689010
Pubmed

TLR3-mediated NF-{kappa}B signaling in human esophageal epithelial cells.

TLR3 RELA

4.97e-06278219779021
Pubmed

Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.

FLNA FLNB

4.97e-06278221325628
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

4.97e-06278210679933
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

4.97e-06278224469451
Pubmed

The limits of promiscuity: isoform-specific dimerization of filamins.

FLNB FLNC

4.97e-06278212525170
Pubmed

Structural and functional aspects of filamins.

FLNA FLNB

4.97e-06278211336782
Pubmed

The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.

FLNA FLNB

4.97e-06278233649519
Pubmed

Depletion of the 26S proteasome adaptor Ecm29 increases Toll-like receptor 3 signaling.

TLR3 ECPAS

4.97e-06278224084648
Pubmed

Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

ILF3 CDC5L ADAR RCC2

5.84e-065278424591637
Pubmed

Single nucleotide polymorphisms in the Wnt and BMP pathways and colorectal cancer risk in a Spanish cohort.

HDAC9 TLE1 ADAR

8.64e-061878320844743
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

FLNA FLNB FLNC

8.64e-061878312119179
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNA FLNB FLNC COL8A1 ILF3 IPO7 PKP4 CGAS EXOC2 CDC5L RFC3 ADAR RPL15

9.25e-061353781329467282
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNA FLNB FLNC IPO7 CLPB FN3KRP IDE CDC5L RFC3 ECPAS RCC2

1.10e-05974781128675297
Pubmed

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.

ILF3 CYB5R3 CDC5L RFC3 ECPAS RCC2

1.16e-0522478628443643
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

ANKRD13B CDK17 FLNB USP13 SCCPDH ILF3 CLPB FBXO31

1.27e-0548178828190767
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

FLNA FLNB ILF3 IPO7 CDC5L ECPAS ADAR RCC2 RPL15

1.32e-0563878933239621
Pubmed

A human MAP kinase interactome.

HDAC9 FLNA FLNC HIVEP2 RELA TAF1 MAP2K5 WDR44

1.37e-0548678820936779
Pubmed

Interaction network of human early embryonic transcription factors.

HIVEP2 TLE1 TLE4 ZNF746 TET1 TAF1 PRDM16

1.44e-0535178738297188
Pubmed

Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.

FLNA FLNB

1.49e-05378228175289
Pubmed

ADAR1 interacts with NF90 through double-stranded RNA and regulates NF90-mediated gene expression independently of RNA editing.

ILF3 ADAR

1.49e-05378216055709
Pubmed

Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection.

ILF3 ADAR

1.49e-05378217079286
Pubmed

Spatio-temporal profiling of Filamin A RNA-editing reveals ADAR preferences and high editing levels outside neuronal tissues.

FLNA ADAR

1.49e-05378224025532
Pubmed

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

FLNA FLNC

1.49e-05378211038172
Pubmed

Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.

FLNA FLNC

1.49e-05378211102480
Pubmed

Cardiac malformations and midline skeletal defects in mice lacking filamin A.

FLNA ERBB3

1.49e-05378216825286
Pubmed

Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.

FLNA FLNC

1.49e-05378217825253
Pubmed

Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.

FLNA FLNC

1.49e-0537829412467
Pubmed

Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.

TLE1 TLE4

1.49e-05378230045946
Pubmed

The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.

FLNA FLNC

1.49e-05378212704190
Pubmed

Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of Herpes Simplex Virus 1 Replication.

TLR3 CGAS

1.49e-05378231896590
Pubmed

GPIbα regulates platelet size by controlling the subcellular localization of filamin.

FLNA FLNB

1.49e-05378222174152
Pubmed

Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.

TLE1 TLE4

1.49e-05378218258796
Pubmed

Lats2 deficiency protects the heart against myocardial infarction by reducing inflammation and inhibiting mitochondrial fission and STING/p65 signaling.

LATS2 RELA

1.49e-05378237497006
Pubmed

Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.

ILF3 RELA

1.49e-05378236208777
Pubmed

Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho-related protein lacking WD40 repeats.

TLE1 RELA

1.49e-05378210660609
Pubmed

Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.

FLNA FLNB

1.49e-05378238989458
Pubmed

Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.

FLNA FLNB FLNC

1.62e-052278318487259
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

FLNA FLNB CACNA2D1 FLNC ILF3 IPO7 CDC5L RFC3 ADAR RCC2 RPL15

1.75e-051024781124711643
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

FLNA FLNB FLNC ERBB3 SCCPDH MAN1A2 TLE1 TLR3 CYB5R3 ADAM17 ADAR SQOR RPL15

1.94e-051451781330550785
Pubmed

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

TLE1 TLE4 GRB14 IDE

2.14e-057278424509480
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

FLNA FLNB ILF3 IPO7 PKP4 CGAS CDC5L RFC3 ADAR SQOR RCC2 RPL15

2.26e-051257781236526897
Pubmed

TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.

TLE1 TLE4

2.97e-0547828645603
Pubmed

Interaction of presenilins with the filamin family of actin-binding proteins.

FLNA FLNB

2.97e-0547829437013
Pubmed

The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.

FLNA FLNC

2.97e-05478220554076
Pubmed

Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but not TLR3 requires the p65 subunit of NF-kappa.

TLR3 RELA

2.97e-05478214557267
Pubmed

Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.

WHRN GPSM2

2.97e-05478228387217
Pubmed

Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube.

TLE1 TLE4

2.97e-05478211290324
Pubmed

Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.

FLNA FLNB FLNC ADAR RPL15

3.02e-0515978534537242
Pubmed

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.

FLNA FLNB FLNC ILF3 IPO7 CYB5R3 RCC2

3.15e-0539778721319273
Pubmed

Comparative Proteomics and Interactome Analysis of the SARS-CoV-2 Nucleocapsid Protein in Human and Bat Cell Lines.

ILF3 CDC5L ADAR RCC2 RPL15

3.93e-0516878539066279
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CLIP4 USP13 SCCPDH IPO7 TLE1 ZNF746 CYB5R3 IDE ECPAS

4.85e-0575478933060197
Pubmed

Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A.

FLNA ROR2

4.94e-05578218667433
Pubmed

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

SEMA5B PLXNA2

4.94e-05578225313870
Pubmed

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.

TLE1 TLE4

4.94e-0557821303260
Pubmed

Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappaB and Sp1.

RELA TAF1

4.94e-0557829584164
Pubmed

Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.

TLE1 TLE4

4.94e-0557828365415
Pubmed

TLR4 signaling induces TLR3 up-regulation in alveolar macrophages during acute lung injury.

TLR3 RELA

4.94e-05578228198368
Pubmed

IL-36γ Induced by the TLR3-SLUG-VDR Axis Promotes Wound Healing via REG3A.

TLR3 IL1RL2

4.94e-05578228774595
Pubmed

Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures.

TLE1 TLE4

4.94e-0557828989517
Pubmed

TBK1 recruitment to STING activates both IRF3 and NF-κB that mediate immune defense against tumors and viral infections.

CGAS RELA

4.94e-05578233785602
Pubmed

Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C.

NPC1 CGAS

4.94e-05578234290407
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

NPC1 FLNA FLNB FLNC SCCPDH CYB5R3 RELA IDE RFC3 ECPAS ADAR RCC2

5.11e-051367781232687490
Pubmed

Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.

FLNA FLNB ILF3 CDC5L ADAR RPL15

5.45e-0529578626209609
Pubmed

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.

CACNA2D1 ADAM17 LRP1B

5.64e-053378324159190
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

CLIP4 USP13 SCCPDH TLE1 CYB5R3 IDE

5.76e-0529878632353859
Pubmed

Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule.

CDK17 FLNB COL12A1

6.74e-053578315031101
Pubmed

Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling.

ERBB3 MYOC

7.40e-05678223897819
Pubmed

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1.

TLR3 RELA

7.40e-05678222065573
Pubmed

Vector-capping: a simple method for preparing a high-quality full-length cDNA library.

FLNA FLNB

7.40e-05678216106752
Pubmed

Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.

TLE1 TLE4

7.40e-0567828573724
Pubmed

Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells.

FLNA FLNC

7.40e-0567829006895
Pubmed

Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.

FLNA FLNC

7.40e-05678212679033
Pubmed

Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response.

TLR3 CGAS

7.40e-05678232715615
Pubmed

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development.

TLE1 TLE4

7.40e-0567828892234
InteractionPTEN interactions

NPC1 EEFSEC FLNA FLNB USP13 ERBB3 SCCPDH ILF3 IPO7 CYB5R3 IDE RFC3 ADAR SQOR RCC2

2.31e-069297815int:PTEN
InteractionCHMP4B interactions

FLNA FLNB FLNC ILF3 IPO7 FN3KRP CGAS CYB5R3 TAF1 RFC3 ADAR RCC2 RPL15

3.99e-067277813int:CHMP4B
InteractionTRIM55 interactions

FLNA FLNB FLNC USP13 ILF3 GRB14 RELA CDC5L SPSB2

7.34e-06345789int:TRIM55
InteractionBIRC3 interactions

FLNA FLNB ILF3 IPO7 CLPB FN3KRP TLR3 SMC6 CYB5R3 RELA IDE CDC5L RFC3 ADAR RCC2 TMEM117 RPL15

1.07e-0513347817int:BIRC3
InteractionRALA interactions

NPC1 FLNA FLNB ILF3 CYB5R3 EXOC2

1.46e-05136786int:RALA
InteractionLGALS9 interactions

NPC1 FLNA FLNB FLNC ILF3 IPO7 CGAS CYB5R3 ADAR RCC2 RPL15

1.57e-055887811int:LGALS9
InteractionTANC2 interactions

FLNA FLNB FLNC LATS2 CDC5L

2.46e-0589785int:TANC2
InteractionACTB interactions

FLNA FLNB FLNC ERBB3 SCCPDH ILF3 MYOC TLE1 CYB5R3 CDC5L IL1RL2 WDR44 CYB5R1 RPL15

6.27e-0510837814int:ACTB
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#4_top-relative-expression-ranked_500

COL8A1 COL12A1 CYB5R3 SQOR

1.39e-0540784gudmap_kidney_adult_Mesangium_Meis_k4_500
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_500

HDAC9 CACNA2D1 COL8A1 COL12A1 HIVEP2 TLR3 CYB5R3 SQOR IL1RL2

2.74e-05429789gudmap_kidney_adult_Mesangium_Meis_500
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRDM11 FBXO31 FN3KRP IDE SPSB2 TMEM117

7.88e-07181786f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HDAC9 FLNB TLE1 PKP4 NMUR2 LRP1B

1.15e-061937867261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

HDAC9 FLNA FLNB HMCN2 PRDM16

1.75e-05183785818fd886e0188091310825f9145fa53328f2c979
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

FLNC COL8A1 COL12A1 HMCN2 ROR2

1.80e-051847850b336489c10e8c3c957795dd845454f03404382b
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

NPC1 CLIP4 ERBB3 IPO7 TMEM117

1.80e-05184785d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLNB COL8A1 GRB14 HSPA12B PLXNA2

1.84e-05185785a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

HDAC9 FLNA FLNB HMCN2 PRDM16

1.99e-0518878534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HDAC9 FLNA FLNB COL8A1 HMCN2

2.04e-051897856b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 SCCPDH GRB14 HSPA12B PLXNA2

2.15e-05191785df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

USP13 NFATC3 GRB14 PRDM16 PLXNA2

2.15e-05191785ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FLNB ERBB3 NFATC3 FBXO31 TMEM117

2.26e-05193785503a979328c68b096680b71359a26f02fafdff35
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 HMCN2 NMUR2 HSPA12B PLXNA2

2.37e-051957856bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell(2)_NK/T-(22)_CD8+_T_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

WHRN SCCPDH TLE1 ROR2 RPL15

2.49e-0519778520dad8e4ed36a0185e231ddcb327725d2b2005e0
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ANKRD13B COL8A1 COL12A1 HMCN2 HSPA12B

2.61e-0519978507b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB COL12A1 HIVEP2 PKP4 ADAR

2.68e-052007852d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA2D1 PKP4 ROR2 TET1 TMEM117

2.68e-05200785682960e28542a3d6c119047cd0131941932cfdea
ToppCellControl_saline-Endothelial-Endothelial-Vein|Control_saline / Treatment groups by lineage, cell group, cell type

HDAC9 FLNB TLE1 HSPA12B LRP1B

2.68e-05200785e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell(09)_Ionocytes-(3)_72hpi|(09)_Ionocytes / shred by cell type and Timepoint

FLNA SCCPDH TLE4 TET1

4.20e-05110784fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FLNA OVGP1 LATS2 RCC2

1.19e-041447840b94d978262a826c9254145aa98c6c30240243f9
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GALNTL6 TTLL6 GNMT

1.30e-0456783ad76712e6a99072f9c6dab6d746db54f754e14fd
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GALNTL6 TTLL6 GNMT

1.30e-045678320a2977f41d3ecbc4fbee7ecd6dfb4b7ce0e4bb7
ToppCell368C-Fibroblasts-Fibroblast-H-|368C / Donor, Lineage, Cell class and subclass (all cells)

COL8A1 FBXO31 ROR2 GPSM2

1.47e-04152784dbfb4d4de36ef9f5c7da1950baa915b12788685e
ToppCell368C-Fibroblasts-Fibroblast-H|368C / Donor, Lineage, Cell class and subclass (all cells)

COL8A1 FBXO31 ROR2 GPSM2

1.47e-041527849f3682da00fd627e80aa820ecc6f5fed23b9738a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GALNTL6 ERBB3 SEMA5B LRP1B

1.59e-0415578477fdae85d36efb776db977eb424b32487ef222e4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 HMCN2 HSPA12B PLXNA2

2.01e-04165784a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HDAC9 SEMA5B NMUR2 GNMT

2.01e-041657843d14f37b8a9c0ddc1130e60a2e08556bad1fb855
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP13 TTLL6 ROR2 TMEM117

2.11e-04167784743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP13 TTLL6 ROR2 TMEM117

2.11e-041677841adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDPD4 CACNA2D1 COL8A1 ROR2

2.21e-04169784849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 RFC3 HSPA12B PLXNA2

2.21e-04169784c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_RSAD2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL8A1 COL12A1 SEMA5B TLE4

2.26e-0417078463dfbc4746717132dc81b6bac868c7498fc96283
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EEFSEC HDAC9 PRDM11 ILF3

2.36e-04172784b043d4f81dced7fb3326043f68474123be47cc5d
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ERBB3 FSCN2 GRB14

2.42e-04697833da27f504e82277fa4a8fb67d60fc26dee0a414f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRB14 GPSM2 PRDM16 TMEM117

2.47e-041747845f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCell343B-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

FLNB USP13 PSKH1 SPSB2

2.52e-04175784b30589ff9dc18e745afe61f289e6d576c9c6c6b2
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

USP13 IPO7 TLE4 PLXNA2

2.52e-04175784711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

FBXO31 TLE1 SUSD3

2.52e-047078337e34ef782b253c43628d5bb2fe5e0294573d0ef
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

HDAC9 CACNA2D1 FLNC USP13

2.58e-041767849df7a124ebafb0087da0cda133a394275d7bed81
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDPD4 CACNA2D1 COL8A1 ROR2

2.58e-04176784fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDPD4 CACNA2D1 COL8A1 ROR2

2.58e-04176784f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

WHRN FBXO31 PKP4 IL1RL2

2.63e-04177784eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR2 GRB14 PRDM16 TMEM117

2.63e-04177784f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC MYOC GRB14

2.75e-04179784e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

COL8A1 COL12A1 SEMA5B TLE4

2.75e-04179784e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIP4 WHRN OVGP1 GRB14

2.75e-04179784ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLIP4 WHRN OVGP1 GRB14

2.75e-04179784c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCellIPF-Epithelial-Mesothelial|IPF / Disease state, Lineage and Cell class

CACNA2D1 FLNC COL8A1 ROR2

2.81e-041807841fa54bf4dba72866b2295639d991af639341bc08
ToppCellNeuroendocrine-neuroendo-1|World / Class top

CACNA2D1 COL8A1 PLXNA2 TMEM117

2.81e-0418078450fdd182a083380899b5943cb5f55ffd77e2a7d4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA MYOC GRB14 PLXNA2

2.93e-0418278437547b36264090b49a193a8ef3a8d88e647f0b79
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

HDAC9 CACNA2D1 FLNC USP13

2.93e-04182784287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 SEMA5B TLE4 PLXNA2

2.93e-0418278472e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 SEMA5B TLE4 PLXNA2

2.93e-0418278405c167158815bf25d509df59ab386e1990712765
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

CACNA2D1 FLNC COL8A1 ROR2

2.99e-041837847df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HDAC9 FLNA FLNB HMCN2

2.99e-04183784cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FLNB COL8A1 ERBB3 COL12A1

2.99e-041837846821dca076318115d360ff426eb1218cfe104063
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

USP13 PKP4 PRDM16 LRP1B

3.05e-04184784e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA2D1 COL8A1 COL12A1 HMCN2

3.11e-041857848f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 COL8A1 SEMA5B TLE4

3.11e-0418578434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPC1 GRB14 TMEM117 RPL15

3.11e-041857849438097e94219c1db922b8507e3a29106d32a923
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP4 COL8A1 SEMA5B TLE4

3.11e-041857848816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HDAC9 FLNB NMUR2 LRP1B

3.18e-0418678492092f11ecce22c14f244e42c499af0822977e6f
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

FLNC ERBB3 GPSM2 WDR44

3.18e-041867846259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCellfacs-Skin-Anagen-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 SCCPDH MYOC FN3KRP

3.24e-04187784908df5520142d65fe32a003d26be14965082a1ea
ToppCellfacs-Skin-Anagen-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 SCCPDH MYOC FN3KRP

3.24e-04187784c1dfab0b0d7f519b9f13f4e0365ab41c4b2ae1ec
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

CDK17 FLNB PRDM16 PLXNA2

3.24e-0418778440ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

NPC1 USP13 HIVEP2 SPSB2

3.24e-04187784030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 PKP4 PRDM16 LRP1B

3.24e-041877847ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellfacs-Skin-Anagen-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 SCCPDH MYOC FN3KRP

3.24e-04187784b486cc5ac678051fea9d4c7db53b26a5a8427e60
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNB GRB14 PRDM16 LRP1B

3.24e-04187784f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

USP13 PKP4 PRDM16 LRP1B

3.31e-041887842ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

HDAC9 FLNB PKP4 NMUR2

3.31e-04188784d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPC1 COL8A1 COL12A1 PLXNA2

3.31e-0418878443a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC COL8A1 MYOC ROR2

3.31e-04188784bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CLIP4 FLNC HMCN2 MYOC

3.31e-04188784409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 PKP4 PRDM16 LRP1B

3.31e-041887843cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 GRB14 PRDM16 LRP1B

3.38e-04189784f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 GRB14 UCN3 PRDM16

3.38e-041897845d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HDAC9 FBXO31 RFC3 HSPA12B

3.38e-04189784bccb3481ffed597c845fe860da658505316105b5
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK17 FLNB COL8A1 HSPA12B

3.38e-04189784d17e8467699c7ca7694a313c26111f085df5204e
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CACNA2D1 FLNC ERBB3 COL12A1

3.38e-04189784473b01c9162b12b90a617c600238436177a0d18d
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CLIP4 ERBB3 GRB14 PRDM16

3.38e-041897847659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

CDK17 FLNB TLE1 PLXNA2

3.38e-04189784c81787a8c662db5d7814c583dd64562857629e81
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNB GRB14 PRDM16 LRP1B

3.38e-04189784e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellSevere-MAIT|World / Disease group and Cell class

HDAC9 USP13 LATS2 TLE1

3.44e-041907847a92e0d6a021be23125495927b8571e25c83204a
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WHRN SYNRG TLE1 ROR2

3.44e-0419078405e6af222d0ad97cb69f399a96c9038f9dd989b9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL8A1 COL12A1 HMCN2 ROR2

3.44e-04190784efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellfacs-MAT-Fat-18m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 HSPA12B PRDM16 PLXNA2

3.44e-0419078434e56c5e7ea6a8f227dbaefe73cbb8818d18b523
ToppCellfacs-MAT-Fat-18m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 HSPA12B PRDM16 PLXNA2

3.44e-0419078414cdb660ad3aabcf49572173e7628d8b99dcbe6f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 GRB14 PRDM16 LRP1B

3.44e-04190784b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellfacs-MAT-Fat-18m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 HSPA12B PRDM16 PLXNA2

3.44e-041907849aaa48f3aad813c87a45efdbb67d255c94f6e6a4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP13 PKP4 PRDM16 LRP1B

3.44e-04190784cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 COL8A1 HSPA12B PLXNA2

3.51e-04191784b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

NPC1 FLNA SMC6 CYB5R3

3.51e-041917847bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP13 PKP4 PRDM16 LRP1B

3.51e-04191784963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

CDK17 FLNB PKP4 PLXNA2

3.51e-04191784c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

COL8A1 RFC3 PRDM16 LRP1B

3.58e-041927847e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

NPC1 CDK17 HIVEP2 PLXNA2

3.58e-041927848b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

FLNB PKP4 HSPA12B PLXNA2

3.58e-041927848a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HDAC9 TLE1 PKP4 LRP1B

3.58e-0419278481baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA MYOC GRB14 PLXNA2

3.65e-041937844aa976b596830b585e8d9c808d5072ed23d13a7c
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNB FLNC

1.71e-083773DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNB FLNC

1.71e-083773DOID:0111190 (implicated_via_orthology)
Diseaseglaucoma

MYOC ROR2 EXOC2 CDC5L LRP1B

5.30e-05154775MONDO_0005041
Diseaseoptic disc size measurement

COL8A1 EXOC2 NMUR2 PRDM16 LRP1B

2.03e-04205775EFO_0004832
Diseasemotion sickness

MAP2K5 PRDM16 LRP1B

2.72e-0448773EFO_0006928
Diseasemyopathy (implicated_via_orthology)

FLNA FLNB FLNC

2.72e-0448773DOID:423 (implicated_via_orthology)
Diseasecleft palate (is_implicated_in)

FLNB ROR2

4.36e-0412772DOID:674 (is_implicated_in)
Diseaseserum dimethylarginine measurement

ADAM17 SQOR LRP1B

6.06e-0463773EFO_0005418
Diseasediffuse idiopathic skeletal hyperostosis

ROR2 CDC5L

6.90e-0415772EFO_0007236
Diseasediabetes mellitus

TLE1 GRB14 IDE

7.58e-0468773EFO_0000400
Diseaseasthma

EEFSEC HDAC9 ERBB3 PRDM11 HIVEP2 IL1RL2 PRDM16 LRP1B

7.60e-04751778MONDO_0004979
Diseasecup-to-disc ratio measurement

FLNB COL8A1 COL12A1 TET1 EXOC2 PRDM16

9.17e-04430776EFO_0006939
Diseasebrain volume measurement

HDAC9 ERBB3 FBXO31 TLE1 EXOC2 PRDM16 PLXNA2

9.30e-04595777EFO_0006930
Diseasemigraine disorder, endometriosis

EXOC2 MAP2K5 LRP1B

9.32e-0473773EFO_0001065, MONDO_0005277
DiseaseDisproportionate short stature

FLNA FLNB ROR2

1.09e-0377773C0878659
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA FLNB

1.12e-0319772DOID:2256 (is_implicated_in)
Diseaseblood metabolite measurement

EXOC2 GNMT

1.12e-0319772EFO_0005664
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB3 RELA

1.12e-0319772DOID:2876 (is_marker_for)
Diseasefacial morphology measurement

EEFSEC HDAC9 COL8A1 ROR2 CDC5L PRDM16

1.38e-03466776EFO_0007841
Diseasehealth study participation

NPC1 SQOR LRP1B PLXNA2

1.72e-03195774EFO_0010130
Diseaseage of onset of childhood onset asthma

EEFSEC NFATC3 EXOC2

1.82e-0392773OBA_2001015
DiseaseColitis

RELA ADAM17

1.94e-0325772C0009319
Diseasedigestive system infectious disorder

NPC1 FLNB

2.10e-0326772MONDO_0043424
Diseasechronic obstructive pulmonary disease

EEFSEC HDAC9 COL8A1 ERBB3 PRDM11 HIVEP2 TLE1

2.13e-03688777EFO_0000341

Protein segments in the cluster

PeptideGeneStartEntry
GDATHKGLYPGSSKP

PKP4

1076

Q99569
HGVLGAKGPIYKYPD

ERBB3

591

P21860
PYEPSGNKKGKTVGF

CDC5L

591

Q99459
FHVRGPPPVYTNGKK

BPIFB4

66

P59827
KPHGKNDGSVGGVQY

CLIP4

521

Q8N3C7
PFYLVPKHAKEGNGF

CGAS

356

Q8N884
SPTFGELGYGDHKPK

RCC2

456

Q9P258
KVYFKDTHPKFPAGG

CYB5R3

111

P00387
ASARKGPEGKYPLHY

ANKRD13B

6

Q86YJ7
VYHAKGKSFGCPGPQ

GPSM2

151

P81274
ARYIGGGPSAFKLPH

LRP1B

4521

Q9NZR2
GIKFHYFPNGSLVPG

NMUR2

186

Q9GZQ4
SAYHGKIPKAPGFEK

FN3KRP

261

Q9HA64
PPKGYGASVEAAGAH

LATS2

231

Q9NRM7
GGPPFHTPKERFYLK

HMCN2

386

Q8NDA2
GPVKAGFPAASQYAH

PSKH1

46

P11801
GYFPVGDGDFPHQKL

ECPAS

866

Q5VYK3
KPGLFKGTYGSHGLE

FBXO31

301

Q5XUX0
YGGPNHIVGSPFKAK

FLNB

2456

O75369
KKIRADGPPHGGVQY

PLXNA2

456

O75051
GYVKDLKGNPGLHSP

EXOC2

391

Q96KP1
IEKHGGYKFSAPVVP

IPO7

1011

O95373
NGGTVYKAYHVPSGK

MAP2K5

176

Q13163
KYGGPQHIVGSPFKA

FLNC

2576

Q14315
AEKEIPGAGYHGQFP

MYOC

356

Q99972
YPALPKSGKEHQGHF

GDPD4

536

Q6W3E5
PGFRNSSYPETGHGK

CDK17

501

Q00537
QHSVLGDFKPYKPGQ

GNMT

266

Q14749
PHGTLKELYKASGGP

HSPA12B

336

Q96MM6
NPNPKCGKGGHAAYS

NPC1

1006

O15118
GYGGSVPKIIYPKNH

IL1RL2

221

Q9HB29
GPPHEPKFVYQAKVG

ADAR

751

P55265
PGEVKGYKVTFHPTG

COL12A1

1111

Q99715
PGAAPKQGAGHRSAY

CACNA2D1

906

P54289
GSHPNKVKVYGPGVA

FLNA

766

P21333
VTYGGHQVPGSPFKV

FLNA

1426

P21333
YGPGLTHGVVNKPAT

FLNA

1871

P21333
YGGPYHIGGSPFKAK

FLNA

2501

P21333
AGKKQPHGGQQKPSY

ILF3

731

Q12906
GIDGVKPPHAYGAKK

COL8A1

591

P27658
PHVDAGKGAKNPGVF

MAN1A2

76

O60476
KKHGAPTNYGFCFKP

GRB14

296

Q14449
AKFIGSPPGYVGHEE

CLPB

421

Q9H078
PKHPFSKFGTGNKYT

IDE

211

P14735
PPLGGYKVTAKCFGH

HDAC9

921

Q9UKV0
AIGPASPGKYTKQEG

OVGP1

281

Q12889
PHLLVYGPSGAGKKT

RFC3

36

P40938
GHYLAPVGPAGTLKA

FSCN2

226

O14926
RSGKGEHGKPYPLTE

GALNTL6

81

Q49A17
GLPEGFAHPKIGSNY

SQOR

156

Q9Y6N5
AYLGLKHFNKPVSGP

SUSD3

161

Q96L08
GHKALGPGSSKKYPS

SYNRG

226

Q9UMZ2
HLPKAGGVFTPGAAF

SCCPDH

391

Q8NBX0
KKYSFGALSQPGPHS

TAF1

621

P21675
EGKNHYTPGGIFAPG

PRDM16

446

Q9HAZ2
PKGHIFGPYEGQIST

PRDM11

171

Q9NQV5
KPGFYKGPAGSQVTL

WHRN

401

Q9P202
KVYKGHLFGPAPGEQ

ROR2

486

Q01974
KNPVGPGKYVFDVGC

RSPH1

166

Q8WYR4
VYLKGVHPKFPEGGK

CYB5R1

116

Q9UHQ9
FKHGGNYVPAPKEGS

OSCP1

231

Q8WVF1
KDKGPYYTHLGAGPS

TET1

1431

Q8NFU7
HGGVCPKAYYSPVGK

ADAM17

361

P78536
INGNPYGLGSKKHPL

C12orf29

201

Q8N999
AFGQSGKFKIHIPGG

EEFSEC

521

P57772
LAGIPGGKPAYSFHV

TLE1

436

Q04724
WKHANPGGPIYFLKG

TLR3

546

O15455
GIPGGKPAYSFHVSA

TLE4

441

Q04727
PKGATYGKPVHHGVN

RPL15

76

P61313
GRGKLYHQSKGPGAP

SPSB2

136

Q99619
RPVKFKAAHGFKGPY

WDR44

481

Q5JSH3
GGHPVVKLLGYNEKP

NFATC3

461

Q12968
RQGHFTYKPVGPLGA

SMC6

496

Q96SB8
TPNHLHYKGGGTPKN

SEMA5B

1076

Q9P283
HYKGGGTPKNEKYTP

SEMA5B

1081

Q9P283
GKLSFFPAHYNPKLG

TTLL6

736

Q8N841
GKGFCYSPVLPVHQK

ZNF226

286

Q9NYT6
KPHEYGQYIGPGQKI

TMEM117

326

Q9H0C3
KYPGRTKGFGHKPGL

ZNF746

426

Q6NUN9
GGPRTGLPHKFYKAK

UCN3

16

Q969E3
FPIHGHSGGYPRKKI

HIVEP2

141

P31629
KTHPTIKINGYTGPG

RELA

56

Q04206
GHGLLSGQYSKPPVK

USP13

391

Q92995