Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 USF1 ZNF418 PRDM15 STAT4	1.00e-09	1459	73	23	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF250 ZNF765 ZNF17 ZNF536 ZNF527 ZNF613 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 USF1 ZNF418 PRDM15 STAT4	1.96e-09	1244	73	21	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF250 ZNF765 ZNF17 ZNF536 ZNF527 ZNF613 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 USF1 ZNF418 PRDM15 STAT4	2.87e-09	1271	73	21	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 USF1 ZNF418 PRDM15 STAT4	3.22e-09	1412	73	22	GO:0000981
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	PRKAG3 LATS1 CAMKV NEK5 NTRK2 NRK CSNK1G1 PRKAA1 DGKH PRKG1 PIPSL	5.02e-05	709	73	11	GO:0016773
GeneOntologyMolecularFunction	kinase activity	PRKAG3 LATS1 CAMKV NEK5 NTRK2 NRK CSNK1G1 PRKAA1 DGKH PRKG1 PIPSL	9.78e-05	764	73	11	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PRKAG3 LATS1 CAMKV NEK5 NTRK2 NRK CSNK1G1 PRKAA1 POLRMT DGKH PRKG1 PIPSL	1.40e-04	938	73	12	GO:0016772
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	PRKAG3 LATS1 CAMKV NEK5 NRK CSNK1G1 PRKAA1 PRKG1	2.20e-04	446	73	8	GO:0004674
GeneOntologyMolecularFunction	protein kinase activity	PRKAG3 LATS1 CAMKV NEK5 NTRK2 NRK CSNK1G1 PRKAA1 PRKG1	3.29e-04	600	73	9	GO:0004672
GeneOntologyMolecularFunction	myosin light chain binding	MYO19 IQGAP3	3.64e-04	8	73	2	GO:0032027
GeneOntologyMolecularFunction	cyclic nucleotide-dependent protein kinase activity	PRKAA1 PRKG1	4.67e-04	9	73	2	GO:0004690
GeneOntologyMolecularFunction	AMP-activated protein kinase activity	PRKAG3 PRKAA1	5.82e-04	10	73	2	GO:0004679
Domain	ZINC_FINGER_C2H2_2	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 RBM10 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	4.77e-15	775	71	23	PS50157
Domain	zf-C2H2	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	5.45e-15	693	71	22	PF00096
Domain	Znf_C2H2-like	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 RBM10 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	8.44e-15	796	71	23	IPR015880
Domain	Znf_C2H2	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 RBM10 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	1.07e-14	805	71	23	IPR007087
Domain	ZnF_C2H2	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 RBM10 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	1.16e-14	808	71	23	SM00355
Domain	-	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	4.33e-14	679	71	21	3.30.160.60
Domain	ZINC_FINGER_C2H2_1	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	5.63e-14	777	71	22	PS00028
Domain	Znf_C2H2/integrase_DNA-bd	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZFHX4 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	6.62e-14	694	71	21	IPR013087
Domain	KRAB	ZNF250 ZNF765 ZNF17 ZNF777 ZNF527 ZNF613 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF418 ZNF282	2.93e-13	358	71	16	PS50805
Domain	KRAB	ZNF250 ZNF765 ZNF17 ZNF777 ZNF527 ZNF613 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF418 ZNF282	2.93e-13	358	71	16	PF01352
Domain	KRAB	ZNF250 ZNF765 ZNF17 ZNF777 ZNF527 ZNF613 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF418 ZNF282	4.65e-13	369	71	16	SM00349
Domain	KRAB	ZNF250 ZNF765 ZNF17 ZNF777 ZNF527 ZNF613 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF418 ZNF282	4.85e-13	370	71	16	IPR001909
Domain	zf-C2H2_6	ZNF250 ZNF765 ZNF17 ZNF527 ZNF613 ZNF584 ZNF540 ZNF197 ZNF620 ZFP28 ZNF420 RREB1 ZNF418 ZNF282	1.10e-11	314	71	14	PF13912
Domain	DUF3669_Znf	ZNF777 ZNF282	2.12e-04	6	71	2	IPR022137
Domain	DUF3669	ZNF777 ZNF282	2.12e-04	6	71	2	PF12417
Domain	S_TKc	LATS1 CAMKV NEK5 NRK CSNK1G1 PRKAA1 PRKG1	4.23e-04	359	71	7	SM00220
Domain	Prot_kinase_dom	LATS1 CAMKV NEK5 NTRK2 NRK CSNK1G1 PRKAA1 PRKG1	5.22e-04	489	71	8	IPR000719
Domain	PROTEIN_KINASE_DOM	LATS1 CAMKV NEK5 NTRK2 NRK CSNK1G1 PRKAA1 PRKG1	5.51e-04	493	71	8	PS50011
Domain	SAM_2	PPFIBP1 DGKH ANKS1A	5.83e-04	43	71	3	PF07647
Domain	Pkinase	LATS1 CAMKV NEK5 NRK CSNK1G1 PRKAA1 PRKG1	6.03e-04	381	71	7	PF00069
Domain	Kinase-like_dom	LATS1 CAMKV NEK5 NTRK2 NRK CSNK1G1 PRKAA1 PRKG1	1.02e-03	542	71	8	IPR011009
Domain	PROTEIN_KINASE_ATP	LATS1 NEK5 NTRK2 NRK CSNK1G1 PRKAA1 PRKG1	1.77e-03	459	71	7	PS00107
Domain	Ser/Thr_kinase_AS	LATS1 NEK5 NRK CSNK1G1 PRKAA1 PRKG1	2.36e-03	357	71	6	IPR008271
Domain	PROTEIN_KINASE_ST	LATS1 NEK5 NRK CSNK1G1 PRKAA1 PRKG1	2.53e-03	362	71	6	PS00108
Domain	Protein_kinase_ATP_BS	NEK5 NTRK2 NRK CSNK1G1 PRKAA1 PRKG1	3.17e-03	379	71	6	IPR017441
Domain	IQ	IQCF3 MYO19 IQGAP3	3.63e-03	81	71	3	SM00015
Domain	SAM	PPFIBP1 DGKH ANKS1A	4.59e-03	88	71	3	SM00454
Domain	IQ_motif_EF-hand-BS	IQCF3 MYO19 IQGAP3	4.88e-03	90	71	3	IPR000048
Domain	IQ	IQCF3 MYO19 IQGAP3	5.35e-03	93	71	3	PS50096
Domain	SAM_DOMAIN	PPFIBP1 DGKH ANKS1A	5.68e-03	95	71	3	PS50105
Domain	SAM	PPFIBP1 DGKH ANKS1A	6.01e-03	97	71	3	IPR001660
Domain	-	PPFIBP1 DGKH ANKS1A	7.68e-03	106	71	3	1.10.150.50
Domain	SAM/pointed	PPFIBP1 DGKH ANKS1A	1.01e-02	117	71	3	IPR013761
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	PRKAG3 ZNF250 GPI ZNF17 ZNF777 ZNF613 PSME4 ZNF584 ZNF540 ZNF197 PRKAA1 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF664 ZNF418 SYT10 ZNF282	2.16e-07	1387	57	20	M734
Pathway	WP_1Q211_COPY_NUMBER_VARIATION_SYNDROME	PRKAG3 PRKAA1 CHD1L	2.13e-04	29	57	3	M39890
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	PRKAG3 ZNF250 GPI PSME4 PRKAA1 ZNF300 ZFP28 ZNF420 ZNF664 ZNF418 ZNF282	2.16e-04	768	57	11	MM14851
Pubmed	Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK.	PRKAG3 PRKAA1	1.30e-05	3	73	2	27797909
Pubmed	Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice.	PRKAG3 PRKAA1	1.30e-05	3	73	2	28467931
Pubmed	Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle.	PRKAG3 PRKAA1	1.30e-05	3	73	2	18818284
Pubmed	Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle.	PRKAG3 PRKAA1	1.30e-05	3	73	2	20197054
Pubmed	5'-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle.	PRKAG3 PRKAA1	1.30e-05	3	73	2	12391032
Pubmed	Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner.	PRKAG3 PRKAA1	1.30e-05	3	73	2	25552597
Pubmed	A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.	PRKAA1 POLRMT	2.60e-05	4	73	2	23283301
Pubmed	Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle.	PRKAG3 PRKAA1	2.60e-05	4	73	2	33798773
Pubmed	Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro.	PRKAG3 PRKAA1	4.33e-05	5	73	2	8626596
Pubmed	Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB early endocytic trafficking and signaling from early endosomes.	NTRK2 SH3GL2	4.33e-05	5	73	2	21849472
Pubmed	Structural basis of AMPK regulation by adenine nucleotides and glycogen.	PRKAG3 PRKAA1	4.33e-05	5	73	2	25412657
Pubmed	Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation.	NTRK2 CHAT	4.33e-05	5	73	2	31541001
Pubmed	Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK).	PRKAG3 PRKAA1	6.48e-05	6	73	2	24563466
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PSME4 PPFIBP1 MYO19 PRKAA1 POLRMT OBSL1 KIF2A IQGAP3	6.59e-05	650	73	8	38777146
Pubmed	Glucose recruits K(ATP) channels via non-insulin-containing dense-core granules.	PRKAG3 PRKAA1	9.06e-05	7	73	2	17767908
Pubmed	Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.	PRKAG3 PRKAA1	9.06e-05	7	73	2	10698692
Pubmed	Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia.	PRKAG3 PRKAA1	1.21e-04	8	73	2	20821366
Pubmed	Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development.	NTRK2 CHAT	1.55e-04	9	73	2	18086710
Pubmed	TSC2 mediates cellular energy response to control cell growth and survival.	PRKAG3 PRKAA1	1.55e-04	9	73	2	14651849
Pubmed	Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.	ZNF300 ZNF350	1.55e-04	9	73	2	23665872
Pubmed	AMPK phosphorylation of raptor mediates a metabolic checkpoint.	PRKAG3 PRKAA1	1.55e-04	9	73	2	18439900
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	RBM10 PRKAA1 KIF2A PHF8	1.61e-04	129	73	4	23022380
Pubmed	Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program.	PRKAG3 PRKAA1 USF1	1.72e-04	51	73	3	20682687
Pubmed	AMPK modulates Hippo pathway activity to regulate energy homeostasis.	LATS1 PRKAA1	1.93e-04	10	73	2	25751139
Pubmed	SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase.	PRKAG3 PRKAA1	1.93e-04	10	73	2	19720090
Pubmed	CLAC-P/collagen type XXV is required for the intramuscular innervation of motoneurons during neuromuscular development.	NTRK2 CHAT	1.93e-04	10	73	2	24453327
Pubmed	GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing.	CHAT PRKG1	2.36e-04	11	73	2	30275816
Pubmed	Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons.	NTRK2 CHAT	2.36e-04	11	73	2	8955272
Pubmed	Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5(-/-):MyoD(-/-) and NT-3(-/-) embryos.	NTRK2 CHAT	2.83e-04	12	73	2	15497153
Pubmed	HDAC1/NFκB pathway is involved in curcumin inhibiting of Tat-mediated long terminal repeat transactivation.	PRKAG3 PRKAA1	2.83e-04	12	73	2	21344388
Pubmed	TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons.	NTRK2 CHAT	2.83e-04	12	73	2	21205893
Pubmed	Dynamic expression of transcription factor Brn3b during mouse cranial nerve development.	NTRK2 CHAT	3.34e-04	13	73	2	26356988
Pubmed	The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1.	NTRK2 CHAT	3.34e-04	13	73	2	22098391
Pubmed	Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3.	NTRK2 CHAT	3.89e-04	14	73	2	11581159
Pubmed	Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor.	NTRK2 SH3GL2	3.89e-04	14	73	2	11157096
Pubmed	Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.	SH3GL2 PRDM15	3.89e-04	14	73	2	22451204
Pubmed	A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange.	NTRK2 CHAT	5.12e-04	16	73	2	35714603
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF250 ZNF17 ZNF197 ZNF620	5.84e-04	181	73	4	37372979
Pubmed	AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.	PRKAG3 PRKAA1	6.51e-04	18	73	2	16054041
Pubmed	The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.	ZNF765 ZNF282	9.77e-04	22	73	2	31403225
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	PSME4 HAUS5 POLRMT PIPSL	1.05e-03	212	73	4	33853758
Pubmed	Murine chromosomal location of five bHLH-Zip transcription factor genes.	GPI USF1	1.16e-03	24	73	2	8530024
Pubmed	Two-hybrid analysis identifies PSMD11, a non-ATPase subunit of the proteasome, as a novel interaction partner of AMP-activated protein kinase.	PRKAG3 PRKAA1	1.16e-03	24	73	2	19616115
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	KIF2A PHF8 IQGAP3 NOL8	1.25e-03	222	73	4	37071664
Pubmed	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	FBXL20 STAT4	1.37e-03	26	73	2	21399635
Pubmed	A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.	STAT4 ANKS1A	1.47e-03	27	73	2	23740937
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	RBM10 ZNF300 ZFP28 PHF8 USF1 ZNF282 STAT4	1.54e-03	808	73	7	20412781
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF536 SETD5 RBM10 OBSL1 PHF8	1.68e-03	407	73	5	12693553
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	GPI SETD5 NEK5 PPFIBP1 MYO19 OBSL1 RREB1 IQGAP3 LSM1	1.75e-03	1321	73	9	27173435
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 ZFHX4 ZGRF1 POLRMT RREB1	1.88e-03	418	73	5	34709266
Pubmed	Global gene expression analysis of murine limb development.	ZFHX4 AASS USF1	1.94e-03	117	73	3	22174793
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TICRR PSME4 VILL SETD5 PRKAA1 ATP11A KIF2A WDFY1	1.95e-03	1084	73	8	11544199
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	ZNF250 ZFHX4 NTRK2 CHAT	1.95e-03	251	73	4	29031500
Pubmed	Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons.	ZFHX4 CHAT	2.07e-03	32	73	2	36596814
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	LATS1 AASS PPFIBP1 SH3GL2 HAUS5 PHF8 ANKS1A	2.09e-03	853	73	7	28718761
Interaction	LTBP2 interactions	ZNF765 ZNF17 ZNF777 ZNF664 ZNF282	1.42e-05	85	73	5	int:LTBP2
Interaction	NOTCH2 interactions	ZNF765 ZNF777 LATS1 NTRK2 CSNK1G1 POLRMT OBSL1 ZNF664 ZNF282	2.15e-05	423	73	9	int:NOTCH2
Interaction	FBLN5 interactions	ZNF765 SETD5 POLRMT OBSL1 ZNF620 ZNF282	2.41e-05	159	73	6	int:FBLN5
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	GPI ZNF765 ZNF17 ZNF527 ZNF613 ZNF584 ZNF540 HAUS5 ZFP28 ZNF420 ZNF350 ZNF418	3.80e-07	1192	73	12	chr19q13
Cytoband	19q13.12	ZNF540 HAUS5 ZNF420	2.13e-04	72	73	3	19q13.12
Cytoband	10q11.2	CHAT PRKG1	2.24e-04	14	73	2	10q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	MYO19 RDM1 FBXL20	1.76e-03	149	73	3	chr17q12
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF250 ZNF765 ZNF17 ZNF536 ZNF777 ZNF527 ZNF613 ZNF584 ZNF540 ZNF197 ZNF620 ZNF300 ZFP28 ZNF420 ZNF350 ZNF395 ZNF664 RREB1 ZNF418 PRDM15 ZNF282	6.45e-17	718	50	21	28
GeneFamily	Sterile alpha motif domain containing	PPFIBP1 DGKH ANKS1A	1.85e-03	88	50	3	760
Disease	executive function measurement, cognitive function measurement	ZNF613 ZNF350	3.41e-05	4	71	2	EFO_0008354, EFO_0009332
Disease	Tourette syndrome, schizophrenia	ZNF536 MYO19	8.52e-04	18	71	2	EFO_0004895, MONDO_0005090
Disease	Varicose veins	PPFIBP1 RREB1 FBXL20 MYBPC1	1.22e-03	193	71	4	HP_0002619
Disease	Cerebral Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0750935
Disease	Intracranial Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0750936
Disease	Pilocytic Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0334583
Disease	Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0280783
Disease	Diffuse Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0280785
Disease	Grade I Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0205768
Disease	Mixed oligoastrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0547065
Disease	Childhood Cerebral Astrocytoma	LATS1 NTRK2	1.65e-03	25	71	2	C0338070
Disease	Gemistocytic astrocytoma	LATS1 NTRK2	1.79e-03	26	71	2	C0334581
Disease	Protoplasmic astrocytoma	LATS1 NTRK2	1.79e-03	26	71	2	C0334580
Disease	Fibrillary Astrocytoma	LATS1 NTRK2	1.79e-03	26	71	2	C0334582
Disease	systemic scleroderma, systemic lupus erythematosus	STAT4 ANKS1A	1.79e-03	26	71	2	EFO_0000717, MONDO_0007915
Disease	Anaplastic astrocytoma	LATS1 NTRK2	1.93e-03	27	71	2	C0334579

Protein segments in the cluster

Peptide	Gene	Start	Entry
GNVLHILTHKRLLKF	PRKAG3	316	Q9UGI9
LSKGLHHKAVLAVRR	AASS	16	Q9UDR5
IARLVLKSKNGIHLR	CYP4A11	491	Q02928
VNVLKVQLLGHRKRI	ANKS1A	811	Q92625
ALHQVKQQILISRKH	BBOF1	366	Q8ND07
VKGHRSQKHKERIRL	C18orf25	171	Q96B23
KEALIRHQQLSGLHK	RBM10	771	P98175
IHILRKRRNDVFKIH	GPR107	281	Q5VW38
VKVRLGTRHKAVQHQ	RDM1	91	Q8NG50
RIEQKGLQHRLILHA	OBSL1	671	O75147
ILANRIQQHIKKLIH	nan	546	O00370
VVALLALVLHHQRKR	LDLRAD3	186	Q86YD5
LKSHQQRLHRKKQLE	LATS1	651	O95835
VLHHLSIKRAIQVLR	PPFIBP1	766	Q86W92
KHIQRLHAAATVIKR	MYO19	801	Q96H55
ILKKRHIVDTRQQEH	PRKG1	391	Q13976
LIGRQGNKKEHVIHI	CSNK1G1	171	Q9HCP0
KLNIHRVHGQLRGLD	KIAA1109	1821	Q2LD37
LVLHQTVERIHVGKK	LSM1	41	O15116
KVRKHQRKFLQAIHQ	KCNN3	596	Q9UGI6
QISLGLKHIHDRKIL	NEK5	111	Q6P3R8
SRHVKKLQLIEGRQH	NLRP1	761	Q9C000
IRKGLHHKILLANFL	GPI	416	P06744
ILQHVHSQRTVKKIR	HAUS5	46	O94927
HKLHSLIGLGIKNRV	NOL8	346	Q76FK4
IKLQHHRIAQCRTVK	DGKH	896	Q86XP1
QKLLLAQLHHRKRVK	IQCF3	21	P0C7M6
HRHRRKAELVKLQAT	IQGAP3	1476	Q86VI3
ALKHRQGNNHKIRII	PIPSL	581	A2A3N6
HAVFQIILRRKGKLH	KIF2A	436	O00139
LHSLKIVHRNLKLEN	CAMKV	136	Q8NCB2
HRIGQNKSVKVIRLI	CHD1L	456	Q86WJ1
LVVHHGQRQKRKLLT	POLRMT	246	O00411
HRVIHRDIKGQNVLL	NRK	171	Q7Z2Y5
LHGLQNRSHGKIKLR	PIGB	21	Q92521
HGIRRKLIKQLGEHK	PRDM15	721	P57071
GIKRLRTHLPNIKVH	FBXL20	396	Q96IG2
LQLGRVTRVQKHRKI	SETD5	271	Q9C0A6
KRKRHLVSQRHLVSQ	SPATA31C1	61	P0DKV0
HELTGHKVAVKILNR	PRKAA1	46	Q13131
HLLKHVTQSSRKLIR	CHAT	456	P28329
IDQGLITRHHLKKRA	C11orf98	41	E9PRG8
HFIQHGKLVRKQSRK	ATP11A	131	P98196
QHIKRHNIVLKRELG	NTRK2	531	Q16620
RKTFIQIGHLNQHKR	ZFP28	791	Q8NHY6
KVKLNLVQHVRSVKH	ZFHX4	1031	Q86UP3
AFIRRGNLKEHLKIH	ZNF540	531	Q8NDQ6
LKKSLIGHQRIHTRE	ZNF197	801	O14709
VHKQISKRLLHRQIK	TICRR	971	Q7Z2Z1
KRTLLQHQRIHTGEK	ZNF250	351	P15622
LKHSLVRHQRIHQKA	RREB1	1551	Q92766
LREIQHHLKKLEGRR	SH3GL2	151	Q99962
HNLKRIRKVLQGKFH	STAT4	81	Q14765
NSLLIRHQIIHTGKK	ZNF620	236	Q6ZNG0
KITLIQHQRVHTGEK	ZNF620	376	Q6ZNG0
LRSIVGIKRHVKALH	ZNF395	291	Q9H8N7
ENRLHGKKQHIRALL	PSME4	926	Q14997
TALKEHLIKHARVQR	SYT10	146	Q6XYQ8
LFNIQRLLHIKGRKH	VILL	131	O15195
KQKLIVHQRTHTGER	ZNF350	386	Q9GZX5
GNLKIHLRTHKLGNL	ZNF536	171	O15090
QRVHTKERNHLKISV	ZNF664	246	Q8N3J9
KLFRGKSHLIEHQRV	ZNF418	461	Q8TF45
HKLGTNRTLLKQVRV	ZGRF1	1771	Q86YA3
GFIKKSRLINHQRVH	ZNF613	296	Q6PF04
LSQLILHKRIHTGEK	ZNF420	291	Q8TAQ5
KSKLQIHRRIHTGEK	ZNF765	311	Q7L2R6
TAKQRLGRILKIHRN	PHF8	1041	Q9UPP1
RLKINLIIHQRNHIK	ZNF777	556	Q9ULD5
TLLQHKKVHTPERRQ	ZNF584	396	Q8IVC4
RKGRTLLLQGHHDKV	WDFY1	231	Q8IWB7
KSQLIVHQRIHTGKK	ZNF300	281	Q96RE9
KAFLRKSHLLQHQRI	ZNF17	281	P17021
FIRKQNLLKHQRIHT	ZNF282	611	Q9UDV7
KNKNLLLRAQLRHHG	USF1	286	P22415
ILSLRLHQRIHAGEK	ZNF527	566	Q8NB42
HKGRIHKLVIANALT	MYBPC1	481	Q00872