Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	transcription factor TFIIIB complex	BDP1 BRF1	1.33e-04	3	140	2	GO:0000126
GeneOntologyCellularComponent	piccolo histone acetyltransferase complex	EPC2 EPC1	2.65e-04	4	140	2	GO:0032777
Domain	Enhancer_polycomb	EPC2 EPC1	5.11e-05	2	134	2	IPR024943
Domain	Enhancer_polycomb_C	EPC2 EPC1	5.11e-05	2	134	2	IPR009607
Domain	E_Pc_C	EPC2 EPC1	5.11e-05	2	134	2	PF06752
Domain	DUF1220	NBPF11 NBPF9 NBPF14	5.71e-05	11	134	3	PF06758
Domain	NBPF_dom	NBPF11 NBPF9 NBPF14	5.71e-05	11	134	3	IPR010630
Domain	NBPF	NBPF11 NBPF9 NBPF14	5.71e-05	11	134	3	PS51316
Domain	LAM_G_DOMAIN	EYS FAT1 CNTNAP2 USH2A	1.55e-04	38	134	4	PS50025
Domain	Laminin_G_2	EYS FAT1 CNTNAP2 USH2A	1.89e-04	40	134	4	PF02210
Domain	LamG	EYS FAT1 CNTNAP2 USH2A	2.75e-04	44	134	4	SM00282
Domain	DUF1908	MAST2 MAST3	3.04e-04	4	134	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST2 MAST3	3.04e-04	4	134	2	IPR015022
Domain	MAST_pre-PK_dom	MAST2 MAST3	3.04e-04	4	134	2	IPR023142
Domain	-	MAST2 MAST3	3.04e-04	4	134	2	1.20.1480.20
Domain	PHD	TCF20 MLLT10 NSD3 SP140L PHF3	4.52e-04	89	134	5	SM00249
Domain	Znf_PHD	TCF20 MLLT10 NSD3 SP140L PHF3	5.01e-04	91	134	5	IPR001965
Domain	ZF_PHD_2	TCF20 MLLT10 NSD3 SP140L PHF3	6.10e-04	95	134	5	PS50016
Domain	ZF_PHD_1	TCF20 MLLT10 NSD3 SP140L PHF3	6.39e-04	96	134	5	PS01359
Domain	Znf_FYVE_PHD	TCF20 PCLO MLLT10 NSD3 SP140L PHF3	6.74e-04	147	134	6	IPR011011
Domain	PDZ	MAGI1 PCLO MAST2 TIAM2 SNTB1 MAST3	7.76e-04	151	134	6	PS50106
Domain	Laminin_G	EYS FAT1 CNTNAP2 USH2A	7.96e-04	58	134	4	IPR001791
Domain	PDZ	MAGI1 PCLO MAST2 TIAM2 SNTB1 MAST3	8.03e-04	152	134	6	IPR001478
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CCP110 EPC2 VPS72 DLGAP5 XRCC1 SRBD1 TRIP12 MECP2 LUZP1 NSD3 ESCO2 CCDC66 TBC1D31 ZNF592 RECQL5 EPC1 HADHA PHIP	1.76e-10	645	142	18	25281560
Pubmed	Human transcription factor protein interaction networks.	SOX6 EPC2 RPL27A EDC3 TCF20 ATN1 VPS72 ATXN7L1 SH3KBP1 R3HDM2 ZNF217 XRCC1 MLLT10 ANKHD1 FAT1 ZNF592 DGKK RECQL5 EPC1 MKI67 N4BP1 HADHA MBD2 SNTB1 GABPA	7.72e-10	1429	142	25	35140242
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	EPC2 ATN1 VPS72 TCOF1 ATXN7L1 ZNF618 SCEL ANKHD1 MAST2 MECP2 ADCY9 LUZP1 NSD3 MLKL FAT1 TC2N ZNF592 EPC1 MACF1 MBD2 PHIP	5.86e-09	1116	142	21	31753913
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF8 NBPF11 NBPF9 NBPF10 NBPF14	2.04e-08	21	142	5	16079250
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NBPF8 MAP4 NBPF11 FAT1 BRF1 NBPF9 NBPF10 NBPF14 HYDIN	3.69e-08	170	142	9	23314748
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	MAGI1 REC114 VPS13C MDGA2 EYS SLC8A3 GPR158 CNTNAP2 USH2A	1.42e-07	199	142	9	23382691
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	MAGI1 EPC2 RPL27A EDC3 VPS72 XRCC1 MAST2 MEAK7 MECP2 NSD3 ARG1 LPIN1 FAT1 PHF3 TMOD1	1.64e-07	689	142	15	36543142
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EPC2 RPL27A TCF20 VPS72 TCOF1 CENPF APTX DLGAP5 XRCC1 SRBD1 PNISR TRIP12 MECP2 NSD3 PHF3 RECQL5 EPC1 MKI67 HADHA MBD2	3.36e-07	1294	142	20	30804502
Pubmed	The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.	TPST1 VPS13C PCLO CPD PNISR ANKRD36	5.21e-07	72	142	6	33726789
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TCF20 DLGAP5 XRCC1 SRBD1 TRIP12 MECP2 NSD3 ZNF592 PHF3 RECQL5 MKI67 PHIP GABPA	1.39e-06	608	142	13	36089195
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	EDC3 ATN1 TCOF1 CENPF RPS16 MECP2 CCNT2 MACF1	1.61e-06	197	142	8	20811636
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DNAH3 EDC3 CENPF ZNF618 VPS13C PCLO RPS16 AGPS TRIP12 DENND6A ZNF592 HADHA MAPK9 DOP1B	2.12e-06	736	142	14	29676528
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAGI1 CCP110 EDC3 TCF20 MAP4 MAST2 ARHGEF16 TRIP12 NARS2 LUZP1 NSD3 PHF3 STARD9 MACF1 DOP1B	2.64e-06	861	142	15	36931259
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TCF20 TCOF1 MAP4 CENPF RPS16 ANKHD1 TRIP12 IGF2R PHF3 MKI67 MACF1 HADHA PHIP	3.05e-06	653	142	13	22586326
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EDC3 VPS72 MAP4 APTX NBPF26 ZNF217 XRCC1 SRBD1 ANKHD1 PNISR MECP2 LUZP1 NSD3 JARID2 ZNF592 PHF3 RECQL5 MACF1 MBD2 GABPA	3.15e-06	1497	142	20	31527615
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TCF20 ATN1 TCOF1 MAP4 DLGAP5 ZNF217 PNISR TRIP12 MECP2 ZNF551 CCNT2 ZNF592 PHF3 MKI67	3.78e-06	774	142	14	15302935
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	RPS16 ANKHD1 LUZP1 MKI67 MACF1	4.07e-06	58	142	5	37117185
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TCF20 TCOF1 TRIP12 ZNF592 MKI67 MBD2	4.30e-06	103	142	6	32744500
Pubmed	Identification of disease-relevant modulators of the SHH pathway in the developing brain.	PTTG3P ULK4 PTTG2	5.50e-06	9	142	3	34463328
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	DNAH3 TCF20 ANKHD1 LPIN1 PHF3 STARD9 MKI67 HSPA14	5.58e-06	233	142	8	37704626
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	BDP1 CCP110 ZFP3 ATXN7L1 SH3KBP1 XRCC1 CPS1 NARS2 TIAM2 LUZP1 EVI5 LPIN1 ADGRG7 FAT1 RECQL5 HSPA14 HYDIN DOP1B	5.86e-06	1293	142	18	15342556
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	TCF20 R3HDM2 TRIP12 NSD3 PHIP UTP14C	5.97e-06	109	142	6	33554859
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RPL27A MYO1A CENPF PCLO SRBD1 PNISR TRIP12 MECP2 NARS2 LUZP1 TBC1D31 LATS2 STARD9 DGKK MACF1 HADHA ZNF541 GABPA UTP14C	6.92e-06	1442	142	19	35575683
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF8 NBPF9 NBPF14	7.83e-06	10	142	3	22973535
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	URI1 RPS16 XRCC1 MLLT10 TRIP12 MECP2 NSD3 CCNT2 ZNF592 MKI67 PHIP	1.30e-05	533	142	11	30554943
Pubmed	Ulk4 Regulates Neural Stem Cell Pool.	MKI67 ULK4 EML1	1.43e-05	12	142	3	27300315
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	RPL27A TCOF1 MAP4 DLGAP5 RPS16 XRCC1 MECP2 ZNF592 MKI67 HADHA	1.46e-05	441	142	10	31239290
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ATXN7L1 MAST2 TRIP12 CNTNAP2 MACF1 MAST3	1.64e-05	130	142	6	12421765
Pubmed	A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome.	MECP2 MBD2	1.66e-05	2	142	2	11242117
Pubmed	Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation.	MECP2 MBD2	1.66e-05	2	142	2	15939760
Pubmed	XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity.	APTX XRCC1	1.66e-05	2	142	2	29477978
Pubmed	Monocyte expression and soluble levels of the haemoglobin receptor (CD163/sCD163) and the mannose receptor (MR/sMR) in septic and critically ill non-septic ICU patients.	CD163 IGF2R	1.66e-05	2	142	2	24637679
Pubmed	Identification of the human pituitary tumor transforming gene (hPTTG) family: molecular structure, expression, and chromosomal localization.	PTTG3P PTTG2	1.66e-05	2	142	2	10806349
Pubmed	The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals.	EPC2 EPC1	1.66e-05	2	142	2	9735366
Pubmed	Components of the DNA methylation system of chromatin control are RNA-binding proteins.	MECP2 MBD2	1.66e-05	2	142	2	15342650
Pubmed	Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.	HADHA SOAT2	1.66e-05	2	142	2	26715271
Pubmed	Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.	APTX XRCC1	1.66e-05	2	142	2	14755728
Pubmed	Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.	MECP2 MBD2	1.66e-05	2	142	2	14633992
Pubmed	Direct homo- and hetero-interactions of MeCP2 and MBD2.	MECP2 MBD2	1.66e-05	2	142	2	23335972
Pubmed	Defective DNA ligation during short-patch single-strand break repair in ataxia oculomotor apraxia 1.	APTX XRCC1	1.66e-05	2	142	2	19103743
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TCOF1 RPS16 XRCC1 ANKHD1 LUZP1 LPIN1 PTPRB MACF1 GABPA	1.84e-05	360	142	9	33111431
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	MAP4 MAST2 PNISR TRIP12 FAT1 ZNF592 PHF3 MACF1 CPLANE1	1.88e-05	361	142	9	26167880
Pubmed	Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin.	ARG1 MKI67 MERTK	2.92e-05	15	142	3	34721382
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	RPL27A URI1 VPS72 TCOF1 RPS16 AGPS PNISR IGF2R	3.45e-05	300	142	8	28561026
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	TCF20 VPS72 MAP4 DLGAP5 RPS16 XRCC1 TRIP12 MECP2 LUZP1 NSD3 PHF3 RECQL5 MKI67 PHIP	3.87e-05	954	142	14	36373674
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RPL27A TCF20 TCOF1 ZNF618 RPS16 TRIM71 AGPS PNISR TRIP12 MECP2 NSD3 ARG1 CCNT2 MACF1 HADHA	3.88e-05	1082	142	15	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	EDC3 RASA2 MAP4 DLGAP5 ANKHD1 TRIP12 WDFY4 TIAM2 ESCO2 IGF2R TBC1D31 MACF1 HMGXB3 CPLANE1 UTP14C	3.96e-05	1084	142	15	11544199
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	RPL27A TCF20 VPS13C SH3KBP1 FREM1 MACF1	3.96e-05	152	142	6	34299191
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL27A TCF20 RASA2 MAP4 DLGAP5 RPS16 AGPS SRBD1 ANKHD1 TRIP12 LUZP1 ARG1 RECQL5 MKI67 MACF1 HADHA PHIP	3.97e-05	1353	142	17	29467282
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	EPC2 RPL27A TCF20 PCLO ZNF217 XRCC1 EPC1 ZNF518B HADHA	4.03e-05	398	142	9	35016035
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	CCP110 EDC3 TCOF1 MAP4 CENPF DLGAP5 TRIP12 PHF3 EPC1 MKI67	4.44e-05	503	142	10	16964243
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TCOF1 MAP4 APTX TRIM71 AGPS ANKHD1 TRIP12 MECP2 LUZP1 ESCO2 PHF3 STARD9 MKI67 TMOD1 HADHA MBD2 HSPA14	4.68e-05	1371	142	17	36244648
Pubmed	Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.	PTTG3P PTTG2	4.95e-05	3	142	2	11682618
Pubmed	Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging.	PTTG3P PTTG2	4.95e-05	3	142	2	33173537
Pubmed	Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions.	VPS8 TGFBRAP1	4.95e-05	3	142	2	29476049
Pubmed	PTTG1 Reprograms Asparagine Metabolism to Promote Hepatocellular Carcinoma Progression.	PTTG3P PTTG2	4.95e-05	3	142	2	37159932
Pubmed	Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.	PTTG3P PTTG2	4.95e-05	3	142	2	16322543
Pubmed	PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis.	PTTG3P PTTG2	4.95e-05	3	142	2	36737842
Pubmed	Pituitary senescence: the evolving role of Pttg.	PTTG3P PTTG2	4.95e-05	3	142	2	20153804
Pubmed	SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation.	MECP2 MBD2	4.95e-05	3	142	2	25798578
Pubmed	The methyl-CpG binding proteins Mecp2, Mbd2 and Kaiso are dispensable for mouse embryogenesis, but play a redundant function in neural differentiation.	MECP2 MBD2	4.95e-05	3	142	2	19177165
Pubmed	Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.	PTTG3P PTTG2	4.95e-05	3	142	2	10713046
Pubmed	Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells.	SOX6 TRIP12	4.95e-05	3	142	2	23663701
Pubmed	Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells.	ATN1 FAT1	4.95e-05	3	142	2	19131340
Pubmed	Sex-steroid milieu determines diabetes rescue in pttg-null mice.	PTTG3P PTTG2	4.95e-05	3	142	2	16731783
Pubmed	Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.	PTTG3P PTTG2	4.95e-05	3	142	2	16959877
Pubmed	Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells.	PTTG3P PTTG2	4.95e-05	3	142	2	23867215
Pubmed	Characterization of the pituitary tumor transforming gene 1 knockout mouse retina.	PTTG3P PTTG2	4.95e-05	3	142	2	21203837
Pubmed	The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4.	APTX XRCC1	4.95e-05	3	142	2	15380105
Pubmed	PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.	PTTG3P PTTG2	4.95e-05	3	142	2	17652795
Pubmed	DNA topoisomerase IIα and mitosin expression predict meningioma recurrence better than histopathological grade and MIB-1 after initial surgery.	CENPF MKI67	4.95e-05	3	142	2	28301542
Pubmed	Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence.	EYS PHF3	4.95e-05	3	142	2	24961364
Pubmed	Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.	PTTG3P PTTG2	4.95e-05	3	142	2	24395789
Pubmed	Association of rare PTP4A1-PHF3-EYS variants with alcohol dependence.	EYS PHF3	4.95e-05	3	142	2	23324950
Pubmed	The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.	PTTG3P PTTG2	4.95e-05	3	142	2	31073078
Pubmed	A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes.	PTTG3P PTTG2	4.95e-05	3	142	2	34262048
Pubmed	Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis.	PTTG3P PTTG2	4.95e-05	3	142	2	25936962
Pubmed	Methyl-CpG-DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2.	MECP2 MBD2	4.95e-05	3	142	2	12646234
Pubmed	Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.	PTTG3P PTTG2	4.95e-05	3	142	2	17626243
Pubmed	Pituitary tumor transforming gene: an update.	PTTG3P PTTG2	4.95e-05	3	142	2	15281346
Pubmed	Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma.	CENPF MKI67	4.95e-05	3	142	2	20398247
Pubmed	Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs.	PTTG3P PTTG2	4.95e-05	3	142	2	18639540
Pubmed	The FHA domain of aprataxin interacts with the C-terminal region of XRCC1.	APTX XRCC1	4.95e-05	3	142	2	15555565
Pubmed	Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.	PTTG3P PTTG2	4.95e-05	3	142	2	12626748
Pubmed	The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.	APTX XRCC1	4.95e-05	3	142	2	16964241
Pubmed	Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.	PTTG3P PTTG2	4.95e-05	3	142	2	28516917
Pubmed	Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.	PTTG3P PTTG2	4.95e-05	3	142	2	10650958
Pubmed	Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells.	EPC2 EPC1	4.95e-05	3	142	2	24166297
Pubmed	Binding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise.	MECP2 MBD2	4.95e-05	3	142	2	27923996
Pubmed	Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.	PTTG3P PTTG2	4.95e-05	3	142	2	17065388
Pubmed	The cell-intrinsic requirement of Sox6 for cortical interneuron development.	SOX6 KCNC2 MKI67	5.20e-05	18	142	3	19709629
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	NBPF8 RPL27A MAP4 RPS16 NBPF11 STARD9 NBPF9 NBPF10 NBPF14 DYRK3	5.23e-05	513	142	10	25798074
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RPL27A TCF20 TCOF1 CENPF DLGAP5 RPS16 ZNF217 SRBD1 TRIP12 ZNF592 PHF3 MKI67 HADHA MBD2	5.69e-05	989	142	14	36424410
Pubmed	The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.	EPC2 VPS72 EPC1	6.15e-05	19	142	3	15647280
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RPL27A MAP4 CENPF RPS16 XRCC1 SRBD1 TRIP12 PHF3 MKI67 TMOD1 MACF1 HSPA14	7.02e-05	759	142	12	35915203
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RPL27A TCF20 TCOF1 MAP4 CENPF XRCC1 AGPS TRIP12 ARG1 IGF2R MKI67 MACF1 HADHA PHIP	8.23e-05	1024	142	14	24711643
Pubmed	The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.	CPS1 ARG1 MKI67	8.40e-05	21	142	3	27088858
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	RPL27A EDC3 TCOF1 VPS13C RPS16 AGPS TRIP12 ADCY9 FAT1 DENND6A IGF2R MKI67	8.76e-05	777	142	12	35844135
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	EDC3 XRCC1 SRBD1 ZNF592 PHF3 UTP14C	9.21e-05	177	142	6	26206133
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MAGI1 CCP110 EDC3 R3HDM2 MAST2 LUZP1 LATS2 HADHA SNTB1	9.62e-05	446	142	9	24255178
Interaction	H2BC21 interactions	EPC2 TCF20 VPS72 CENPF ATXN7L1 PCLO APTX XRCC1 MLLT10 SRBD1 TRIP12 MECP2 NSD3 LATS2 PHF3 MKI67 ZNF518B PHIP	1.47e-06	696	139	18	int:H2BC21
Interaction	H2BC8 interactions	EPC2 TCF20 VPS72 DLGAP5 XRCC1 SRBD1 TRIP12 MECP2 NSD3 ESCO2 ZNF592 PHF3 RECQL5 MKI67 PHIP	1.08e-05	576	139	15	int:H2BC8
Interaction	TMEM132D interactions	TPST1 VPS13C PCLO CPD PNISR ANKRD36	1.22e-05	74	139	6	int:TMEM132D
Cytoband	1q21.1	NBPF8 NBPF11 NBPF9 NBPF10 NBPF14	1.48e-06	62	142	5	1q21.1
Cytoband	1q41	CENPF USH2A DISP1 MTARC1	5.45e-05	66	142	4	1q41
Cytoband	Ensembl 112 genes in cytogenetic band chr1q41	CENPF USH2A DISP1 MTARC1	2.07e-04	93	142	4	chr1q41
GeneFamily	Neuroblastoma breakpoint family	NBPF8 NBPF26 NBPF11 NBPF9 NBPF10 NBPF14	8.55e-10	23	85	6	662
GeneFamily	PDZ domain containing	MAGI1 PCLO MAST2 TIAM2 SNTB1 MAST3	8.10e-05	152	85	6	1220
GeneFamily	PHD finger proteins	MLLT10 NSD3 SP140L PHF3	8.55e-04	90	85	4	88
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	MECP2 MBD2	1.17e-03	11	85	2	1025
GeneFamily	Immunoglobulin like domain containing	A1BG MDGA2 ADAMTSL3 MERTK IL1RAP	2.16e-03	193	85	5	594
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	TPST1 URI1 CENPF DLGAP5 R3HDM2 MAST2 PNISR TRIP12 MECP2 ADCY9 EVI5 JARID2 FAT1 IGF2R TBC1D31 PHF3 MACF1 N4BP1 MBD2 IL1RAP NBPF14 PHIP DOP1B	2.35e-10	856	142	23	M4500
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	CENPF ZNF217 PNISR MECP2 ADCY9 JARID2 FAT1 PHF3 MKI67 N4BP1 MBD2 PHIP	9.39e-08	300	142	12	M8702
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	BDP1 RPL27A URI1 RASA2 VPS13C SH3KBP1 RPS16 ZNF217 PNISR TRIP12 MECP2 LUZP1 LPIN1 JARID2 CCNT2 TC2N PHF3 EPC1 MACF1 N4BP1 MBD2 PHIP LDLRAD4 GABPA MAST3	4.34e-07	1492	142	25	M40023
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	MECP2 ADCY9 JARID2 FAT1 PHF3 MKI67 MBD2 PHIP	1.30e-06	145	142	8	M1810
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	CENPF R3HDM2 PNISR TRIP12 MECP2 EVI5 JARID2 FAT1 PHF3 MBD2 IL1RAP PHIP DOP1B	1.63e-06	466	142	13	M13522
Coexpression	ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN	NBPF8 URI1 CENPF VPS13C VPS8 ARHGEF16 WDFY4 MECP2 TIAM2 LUZP1 ADGB ADGRG7 SV2B NBPF10 DCLK3 HMGXB3	2.17e-05	873	142	16	M16009
Coexpression	ENK_UV_RESPONSE_KERATINOCYTE_DN	URI1 MAP4 CPD AGPS TRIP12 MECP2 ADCY9 FAT1 MACF1 MBD2 DOP1B	6.53e-05	481	142	11	M3898
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	RASA2 ATXN7L1 NSD3 MACF1 MERTK PHIP LDLRAD4	7.94e-05	189	142	7	M3112
Coexpression	ZHENG_BOUND_BY_FOXP3	SH3KBP1 ZNF217 AGPS NSD3 EVI5 JARID2 DENND6A LATS2 ULK4 MACF1 LDLRAD4	8.89e-05	498	142	11	M1741
Coexpression	GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN	CCP110 TIAM2 EVI5 KATNBL1 TMOD1 HYDIN UTP14C	9.97e-05	196	142	7	M4431
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN	MAST2 TRIP12 LPIN1 JARID2 IGF2R TBC1D31 PHIP	1.03e-04	197	142	7	M4421
Coexpression	ZHENG_BOUND_BY_FOXP3	SH3KBP1 ZNF217 AGPS NSD3 EVI5 JARID2 DENND6A LATS2 ULK4 MACF1 LDLRAD4	1.04e-04	507	142	11	MM1030
Coexpression	GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP	TCF20 R3HDM2 LUZP1 LPIN1 FCGBP ULK4 MACF1	1.06e-04	198	142	7	M5580
Coexpression	GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP	CPD ZNF217 NARS2 IGF2R N4BP1 SOAT2 DOP1B	1.13e-04	200	142	7	M5282
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	BDP1 MAGI1 TPST1 TCF20 ATN1 MAP4 CENPF SH3KBP1 R3HDM2 CPD ANKHD1 MAST2 MECP2 LUZP1 EVI5 CCDC66 EPC1 MKI67 MACF1 N4BP1 CPLANE1 PHIP UTP14C	1.41e-09	780	139	23	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	SOX6 BDP1 MAGI1 TCF20 ATN1 CENPF PCLO SH3KBP1 MDGA2 R3HDM2 NCKAP5 CPD ANKHD1 MAST2 PNISR MECP2 LUZP1 CCDC66 EPC1 MKI67 PHIP	1.11e-07	831	139	21	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	BDP1 CENPF PCLO LUZP1 CCDC66 MKI67 MACF1 N4BP1 PHIP UTP14C	5.61e-07	192	139	10	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	BDP1 CENPF LUZP1 EVI5 CCDC66 MKI67 MACF1 N4BP1 CPLANE1 PHIP UTP14C	3.51e-06	291	139	11	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500	BDP1 RPL27A CENPF PCLO LUZP1 CCDC66 MKI67 TMOD1 MACF1 N4BP1 MERTK PHIP UTP14C	2.17e-05	492	139	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	SOX6 BDP1 CCP110 EPC2 URI1 TCOF1 CENPF ZNF618 PNISR LUZP1 ESCO2 EVI5 JARID2 CCDC66 PHF3 CNTNAP2 MKI67 MACF1 ZNF518B CPLANE1 PHIP DYRK3	2.25e-05	1257	139	22	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	BDP1 EPC2 URI1 CENPF DLGAP5 MDGA2 PNISR LUZP1 CCDC66 TBC1D31 MKI67 MACF1 N4BP1 PHIP	6.75e-05	629	139	14	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500	BDP1 EPC2 RPL27A MDGA2 LUZP1 CCDC66 DGKK MKI67 TMOD1 MACF1 MERTK LDLRAD4	9.75e-05	492	139	12	Facebase_RNAseq_e10.5_Mandibular Arch_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	SOX6 BDP1 MAGI1 CENPF MDGA2 LUZP1 CCDC66 PHIP	1.48e-04	232	139	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	SOX6 MAGI1 EPC2 CENPF PCLO MDGA2 NCKAP5 CNTNAP2 PHIP	1.56e-04	298	139	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	SOX6 BDP1 CCP110 EPC2 URI1 TCOF1 CENPF ZNF618 PNISR LUZP1 ESCO2 EVI5 JARID2 CCDC66 PHF3 CNTNAP2 MKI67 MACF1 ZNF518B CPLANE1 PHIP DYRK3	2.01e-04	1459	139	22	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	BDP1 MAGI1 CENPF ANKHD1 PNISR LUZP1 CCDC66 MKI67 PHIP	2.14e-04	311	139	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5	BDP1 EPC2 MDGA2 LUZP1 CCDC66 MKI67 MACF1	2.28e-04	186	139	7	Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	SOX6 MAGI1 CCP110 EPC2 ZFP3 CENPF MLLT10 ESCO2 JARID2 FAT1 CCDC66 PHF3 TGFBRAP1 DGKK CNTNAP2 MKI67 ZNF518B EML1 CPLANE1 PHIP DYRK3	2.29e-04	1370	139	21	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000	BDP1 RPL27A CENPF PCLO MECP2 LUZP1 EVI5 CCDC66 IGF2R MKI67 TMOD1 MACF1 N4BP1 MERTK CPLANE1 PHIP UTP14C	2.47e-04	985	139	17	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	BDP1 EPC2 URI1 TCOF1 CENPF PCLO TRIM71 XRCC1 LUZP1 CCDC66 TBC1D31 MKI67 TMOD1 MACF1 N4BP1 PHIP SNTB1	2.59e-04	989	139	17	Facebase_RNAseq_e10.5_Maxillary Arch_1000
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO MDGA2 CPS1 FREM1 FAT1 DGKK USH2A HYDIN	1.41e-07	184	142	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO MDGA2 CPS1 FREM1 FAT1 DGKK USH2A HYDIN	1.41e-07	184	142	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO MDGA2 CPS1 FREM1 FAT1 DGKK USH2A HYDIN	1.41e-07	184	142	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	MDGA2 ADGRG7 EYS SLC8A3 PTPRB CNTNAP2 USH2A	3.24e-07	139	142	7	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	droplet-Spleen-nan-24m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 REC114 CENPF ESCO2 MKI67 TMOD1 DYRK3	1.77e-06	179	142	7	f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCell	droplet-Spleen-nan-24m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 REC114 CENPF ESCO2 MKI67 TMOD1 DYRK3	1.77e-06	179	142	7	01e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCP110 PCLO DLGAP5 ESCO2 TBC1D31 TC2N MKI67	2.13e-06	184	142	7	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF DLGAP5 WDFY4 CD163 SLC35G4 FCGBP MKI67	2.37e-06	187	142	7	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	droplet-Spleen-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1 DYRK3	2.64e-06	190	142	7	a273fc119baebc11020009c923beafeebb6428c9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF DLGAP5 ESCO2 PTPRB SV2B STARD9 MKI67	2.64e-06	190	142	7	31de1727822e9818652946dfb962daee77ffad68
ToppCell	368C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AGPS ESCO2 FCGBP TGFBRAP1 NBPF9 MKI67 CPLANE1	2.92e-06	193	142	7	5f5904cec8b2967154ef2eab3c48f51df53aca4a
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	WDFY4 CD163 MLKL JARID2 MERTK IL1RAP LDLRAD4	2.92e-06	193	142	7	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	WDFY4 CD163 MLKL JARID2 MERTK IL1RAP LDLRAD4	3.02e-06	194	142	7	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BDP1 PNISR LPIN1 TC2N PHF3 MACF1 ANKRD36	3.58e-06	199	142	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VPS13C VPS8 MLLT10 PNISR FAT1 LDLRAD4 UTP14C	3.58e-06	199	142	7	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	CCP110 EDC3 CENPF DLGAP5 ARG1 NBPF9 MKI67	3.70e-06	200	142	7	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BDP1 VPS13C PNISR TRIP12 PHF3 MACF1 PHIP	3.70e-06	200	142	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MDGA2 EYS KCNC2 GPR158 CNTNAP2 USH2A	8.10e-06	148	142	6	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKHD1 ARG1 CNTNAP2 HSPA14 MTARC1 MAST3	1.06e-05	155	142	6	d10cf5e922dbd3ca46660404da5aca43f181fc19
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1A MDGA2 CPD PTPRB SV2B HYDIN	1.06e-05	155	142	6	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DNAH3 MDGA2 EYS GPR158 CNTNAP2 USH2A	1.22e-05	159	142	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCF20 WDFY4 NSD3 FCGBP NBPF10 MACF1	1.22e-05	159	142	6	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPS1 PTCHD4 FREM1 CNTNAP2 USH2A HYDIN	1.26e-05	160	142	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPS1 PTCHD4 FREM1 CNTNAP2 USH2A HYDIN	1.26e-05	160	142	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CENPF DLGAP5 ESCO2 PTPRB TBC1D31 MKI67	1.40e-05	163	142	6	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF DLGAP5 WDFY4 ESCO2 MLKL MKI67	1.67e-05	168	142	6	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EDC3 CENPF DLGAP5 CD163 TIAM2 DYRK3	1.78e-05	170	142	6	7534ac69ca3a378df78d61c284e89bc96a71a4a8
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF618 IGF2R PTPRB LATS2 TGFBRAP1 MTARC1	1.84e-05	171	142	6	943fbca8a6ac04052a2a85aca7b21a3461cd96f7
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REC114 CENPF DLGAP5 ESCO2 MKI67 DYRK3	1.84e-05	171	142	6	ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF DLGAP5 WDFY4 CD163 ESCO2 MKI67	1.84e-05	171	142	6	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	droplet-Marrow-BM_(NON-STC)\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 CENPF ESCO2 MKI67 TMOD1 ANKRD36	1.90e-05	172	142	6	6004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 CENPF ESCO2 MKI67 TMOD1 ANKRD36	1.90e-05	172	142	6	31c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF DLGAP5 ESCO2 ADGB MKI67 DCLK3	2.03e-05	174	142	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF CNMD DLGAP5 ESCO2 MKI67 NBPF10	2.03e-05	174	142	6	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF DLGAP5 MDGA2 ESCO2 PTPRB MKI67	2.10e-05	175	142	6	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CENPF DLGAP5 ESCO2 CNTNAP2 MKI67 NBPF10	2.24e-05	177	142	6	844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCP110 EPC2 SCEL ADAMTSL3 FAT1 KCNC2	2.70e-05	183	142	6	0e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCP110 EPC2 SCEL ADAMTSL3 FAT1 KCNC2	2.70e-05	183	142	6	cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCP110 TCOF1 CENPF DLGAP5 ESCO2 MKI67	2.78e-05	184	142	6	8f40093de5bb978f046d66e8f05f333686a009a4
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX6 CENPF ARG1 MKI67 TMOD1 DYRK3	2.87e-05	185	142	6	e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SOX6 ADAMTSL3 FREM1 HYDIN LDLRAD4 SNTB1	2.96e-05	186	142	6	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK\|GI_small-bowel / Manually curated celltypes from each tissue	CENPF DLGAP5 ESCO2 ADGB FCGBP MKI67	3.05e-05	187	142	6	265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	CENPF DLGAP5 NCKAP5 WDFY4 ESCO2 MKI67	3.14e-05	188	142	6	723348a1836a074e068320cb736ce6a953e0038f
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	WDFY4 CD163 JARID2 FCGBP MERTK LDLRAD4	3.23e-05	189	142	6	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells\|World / Lineage, cell class and subclass	SOX6 CENPF DLGAP5 ARG1 MKI67 TMOD1	3.33e-05	190	142	6	6c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1	3.33e-05	190	142	6	4288189e3a499c395896c950598810b02f401685
ToppCell	droplet-Marrow-BM-30m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1	3.43e-05	191	142	6	08be56a4055a73c920d345fd3b2052a5ccb675d8
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	CENPF WDFY4 CD163 MKI67 MERTK LDLRAD4	3.53e-05	192	142	6	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 PNISR JARID2 PHF3 PHIP SNTB1	3.53e-05	192	142	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	CENPF WDFY4 CD163 MKI67 MERTK LDLRAD4	3.64e-05	193	142	6	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 PNISR JARID2 PHF3 PHIP SNTB1	3.64e-05	193	142	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	LPS-IL1RA-Endothelial-Mes-Like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	REC114 MYO1A MEAK7 SV2B USH2A	3.68e-05	117	142	5	5a23770806b4612bed4ae6fd716abdec7f7f56c6
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CENPF MATN3 CNMD DLGAP5 ESCO2 MKI67	3.74e-05	194	142	6	c093c5e161b97ad770bfbaad3023eba4537101b5
ToppCell	PCW_07-8.5\|World / Celltypes from embryonic and fetal-stage human lung	SOX6 MAGI1 RPL27A CENPF MKI67 ZNF518B	3.74e-05	194	142	6	5759c83308df017f1faae248e9b85388e25254f0
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	CENPF MATN3 CNMD DLGAP5 ESCO2 MKI67	3.74e-05	194	142	6	4a207630d72059345b10010f5cfd3b1462458324
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	BDP1 RPL27A PCLO RPS16 NSD3 EML1	3.74e-05	194	142	6	4903a0d6e36599bcb83b179462e5b949df9eb685
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TPST1 CD163 JARID2 MERTK IL1RAP LDLRAD4	3.85e-05	195	142	6	81a28289eda1a8a1a31b7357106f64ac5000e172
ToppCell	COVID-19_Severe\|World / Disease condition and Cell class	TPST1 CPD ARG1 IGF2R MKI67 MTARC1	3.85e-05	195	142	6	22f56ccb81967bff54a1f90e949a8dfc2ce0e4ab
ToppCell	15-Trachea-RBC-RBC\|Trachea / Age, Tissue, Lineage and Cell class	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1	3.96e-05	196	142	6	511bfc06c34d5add2ae561cca463d1e4e2d43e20
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCLO MDGA2 KCNC2 GPR158 CNTNAP2 ANKRD36	3.96e-05	196	142	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	15-Trachea-RBC\|Trachea / Age, Tissue, Lineage and Cell class	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1	3.96e-05	196	142	6	bf2670e5ae996a19987bc70aa5a37d133db789eb
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-AT1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	SOX6 MATN3 SCEL RECQL5 CNTNAP2 SNTB1	4.08e-05	197	142	6	f7ef62d78336812573148f8bfce401877ec4e29c
ToppCell	21-Trachea-RBC\|Trachea / Age, Tissue, Lineage and Cell class	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1	4.08e-05	197	142	6	9f8eb6305ade0654bbcd8f19963be0b64af083de
ToppCell	erythropoietic-Polychromatic_Erythroblast\|World / Lineage and Cell class	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1	4.08e-05	197	142	6	604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCell	21-Trachea-RBC-RBC\|Trachea / Age, Tissue, Lineage and Cell class	SOX6 CENPF DLGAP5 ESCO2 MKI67 TMOD1	4.08e-05	197	142	6	4710b55806a618076a954190f519e49c55d300d3
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	URI1 TCOF1 VPS13C PHF3 MACF1 ANKRD36	4.19e-05	198	142	6	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCLO MDGA2 KCNC2 GPR158 CNTNAP2 ANKRD36	4.19e-05	198	142	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH3 SCEL ARG1 ADGB FCGBP HYDIN	4.19e-05	198	142	6	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	DNAH3 SCEL ARG1 ADGB FCGBP HYDIN	4.19e-05	198	142	6	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CENPF WDFY4 CD163 FCGBP MKI67 LDLRAD4	4.19e-05	198	142	6	732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCLO MDGA2 KCNC2 GPR158 CNTNAP2 ANKRD36	4.19e-05	198	142	6	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	DNAH3 CENPF DLGAP5 ARG1 MKI67 PTTG2	4.31e-05	199	142	6	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TC2N PHF3 EPC1 MACF1 N4BP1 ANKRD36	4.31e-05	199	142	6	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CENPF DLGAP5 NCKAP5 ZNF551 ESCO2 MKI67	4.31e-05	199	142	6	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 LUZP1 PTPRB MACF1 ZNF518B DISP1	4.43e-05	200	142	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NBPF26 TSBP1 NBPF10 MERTK IL1RAP NBPF14	4.43e-05	200	142	6	47791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX6 MAGI1 PTCHD4 EYS KCNC2 CNTNAP2	4.43e-05	200	142	6	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SOX6 CENPF DLGAP5 MKI67 TMOD1 DYRK3	4.43e-05	200	142	6	f100edfd2b3b742458cbbf34de9c403c4d272d3c
ToppCell	(5)_Epi_dividing\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	TCOF1 CENPF DLGAP5 ESCO2 MKI67 HADHA	4.43e-05	200	142	6	948c55aa1c25f8a69b1bd3ef53fd32aa222f592c
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 LUZP1 PTPRB MACF1 ZNF518B DISP1	4.43e-05	200	142	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX6 MAGI1 PTCHD4 EYS KCNC2 CNTNAP2	4.43e-05	200	142	6	5ec469267747dce3601c1d8ad01af89fa5b29acc
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	BDP1 PCLO MDGA2 KCNC2 CNTNAP2 ANKRD36	4.43e-05	200	142	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	(5)_Epithelial_cells-(5)_Epi_dividing\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	TCOF1 CENPF DLGAP5 ESCO2 MKI67 HADHA	4.43e-05	200	142	6	b46b2064362efc64edf19ab2b21bc89047c9d943
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	URI1 VPS13C PHF3 MACF1 N4BP1 MBD2	4.43e-05	200	142	6	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX6 MAGI1 PTCHD4 EYS KCNC2 CNTNAP2	4.43e-05	200	142	6	e79d93d55b25804f2608185168da472301b6ebca
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NBPF26 TSBP1 NBPF10 MERTK IL1RAP NBPF14	4.43e-05	200	142	6	f75d95376a340d467c4392b872b2a2dbdd184556
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NBPF26 TSBP1 NBPF10 MERTK IL1RAP NBPF14	4.43e-05	200	142	6	fae26560ba3b0b638b6bcf92f05330824b31d21b
ToppCell	Non-neuronal-Dividing-IPC\|World / Primary Cells by Cluster	MAGI1 CENPF DLGAP5 ESCO2 MKI67 PHIP	4.43e-05	200	142	6	971533181daa1bfac1f1b8c507d2013f891f9078
ToppCell	Neuronal-Inhibitory-iB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX6 MAGI1 PTCHD4 EYS KCNC2 CNTNAP2	4.43e-05	200	142	6	45ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SOX6 MAGI1 PTCHD4 EYS KCNC2 CNTNAP2	4.43e-05	200	142	6	320d5a3a1e7da2fa8f1a164e29e180ec8ac9889c
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MDGA2 ADGRG7 EYS CNTNAP2 USH2A	5.65e-05	128	142	5	91072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CENPF DLGAP5 NCKAP5 ESCO2 MKI67	5.87e-05	129	142	5	ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REC114 ARG1 DGKK TMOD1 USH2A	8.36e-05	139	142	5	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATN1 CD163 ADGRG7 EYS SOAT2	8.36e-05	139	142	5	d96e5c17582f1576fa09d6bad35c418b6248448c
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REC114 ARG1 DGKK TMOD1 USH2A	8.36e-05	139	142	5	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	10x5'-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	NCKAP5 WDFY4 FCGBP EML1 MERTK	8.94e-05	141	142	5	7671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SH3KBP1 FAT1 SLC8A3 KCNC2 CNTNAP2	9.55e-05	143	142	5	24fd24846fbef049af669a57d42fcc18928d2b27
ToppCell	droplet-Liver-Npc-21m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A1BG REC114 SRBD1 CCNT2	9.71e-05	75	142	4	7f3be37cc378ee115fcb4b0eb9653fc77447aa0a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF CPS1 ESCO2 MKI67 ZNF541	9.87e-05	144	142	5	f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCell	Control-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NBPF11 WDFY4 NSD3 NBPF10 CPLANE1	9.87e-05	144	142	5	984470ff6ddce4c743e2db78fa98dae055aaa273
Drug	Pesticides	NBPF8 RPS16 XRCC1 NBPF11 NSD3 IGF2R NBPF9 DGKK NBPF10 IL1RAP NBPF14	2.30e-09	150	140	11	ctd:D010575
Drug	PHA-00816795 [212631-79-3]; Down 200; 10uM; PC3; HT_HG-U133A	DNAH3 ATN1 CENPF CPD MAST2 ARHGEF16 NSD3 BRF1 MAST3 DYRK3	4.24e-07	198	140	10	7076_DN
Drug	Pyrilamine maleate [59-33-6]; Up 200; 10uM; HL60; HG-U133A	TPST1 MAP4 CENPF R3HDM2 MAST2 N4BP1 IL1RAP LDLRAD4 SNTB1	4.06e-06	199	140	9	1568_UP
Drug	Isoflupredone acetate [338-98-7]; Up 200; 9.6uM; HL60; HT_HG-U133A	TPST1 CPD MAST2 CD163 ARG1 TMOD1 IL1RAP MTARC1	1.26e-05	174	140	8	1873_UP
Drug	Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; PC3; HT_HG-U133A	ATN1 ARHGEF16 NSD3 LPIN1 BRF1 SV2B RECQL5 SNTB1	2.28e-05	189	140	8	4672_UP
Drug	Methotrexate [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A	CENPF DLGAP5 ARG1 TBC1D31 MKI67 N4BP1 HSPA14 PHIP	2.28e-05	189	140	8	2041_DN
Drug	Indoprofen [31842-01-0]; Down 200; 14.2uM; PC3; HT_HG-U133A	DNAH3 ATN1 MATN3 SCEL ARHGEF16 NSD3 EVI5 CPLANE1	2.75e-05	194	140	8	4249_DN
Drug	(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A	CPD MLLT10 MECP2 RECQL5 TMOD1 N4BP1 MAST3 DYRK3	2.85e-05	195	140	8	5325_UP
Drug	Repaglinide [135062-02-1]; Up 200; 8.8uM; HL60; HT_HG-U133A	TPST1 ATN1 VPS13C MLLT10 CD163 TMOD1 LDLRAD4 MTARC1	2.85e-05	195	140	8	6135_UP
Drug	Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; MCF7; HT_HG-U133A	TPST1 EDC3 MAP4 CPD PNISR MECP2 RECQL5 MTARC1	2.96e-05	196	140	8	7411_DN
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ATN1 MAP4 MECP2 NSD3 RECQL5 CNTNAP2 LDLRAD4 MAST3	3.07e-05	197	140	8	6012_DN
Drug	Cefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; PC3; HT_HG-U133A	ATXN7L1 EVI5 CCNT2 BRF1 TGFBRAP1 CNTNAP2 N4BP1 CPLANE1	3.07e-05	197	140	8	7148_UP
Drug	Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	MAP4 APTX CPS1 ZNF551 BRF1 CPLANE1 SOAT2 DOP1B	3.07e-05	197	140	8	2328_UP
Drug	Piroxicam [36322-90-4]; Up 200; 12uM; MCF7; HT_HG-U133A	MAGI1 AGPS ZNF551 BRF1 TGFBRAP1 RECQL5 MERTK MBD2	3.30e-05	199	140	8	7445_UP
Disease	serum IgG glycosylation measurement	MAGI1 REC114 VPS13C APTX MDGA2 DNM1P46 EYS SLC8A3 GPR158 CNTNAP2 USH2A SNTB1	5.45e-06	523	135	12	EFO_0005193
Disease	gout	TPST1 R3HDM2 FAT1 SV2B CNTNAP2 ZNF518B GABPA	3.46e-05	196	135	7	EFO_0004274
Disease	liver fat measurement	ZNF217 TGFBRAP1 CNTNAP2 MTARC1	4.50e-05	43	135	4	EFO_0010821
Disease	cholesteryl ester 17:0 measurement	MAGI1 SOAT2	6.21e-05	3	135	2	EFO_0021436
Disease	Tourette syndrome, schizophrenia	TCF20 NSD3 PHF3	7.27e-05	18	135	3	EFO_0004895, MONDO_0005090
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	TCF20 CPS1 NARS2 MACF1 MTARC1	1.14e-04	103	135	5	EFO_0008595, EFO_0020944
Disease	retinitis pigmentosa (implicated_via_orthology)	EYS CCDC66 USH2A	2.53e-04	27	135	3	DOID:10584 (implicated_via_orthology)
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	CPS1 NARS2 MACF1 MTARC1	2.57e-04	67	135	4	EFO_0008595, EFO_0020946
Disease	Disorder of the urea cycle metabolism	CPS1 ARG1	3.08e-04	6	135	2	cv:C0154246
Disease	Liver carcinoma	CENPF DLGAP5 MECP2 CD163 ADGRG7 IGF2R GPR158 MKI67 IL1RAP	5.62e-04	507	135	9	C2239176
Disease	Alzheimer disease, survival time	NCKAP5 NARS2	5.71e-04	8	135	2	EFO_0000714, MONDO_0004975
Disease	argininate measurement	ARG1 IGF2R	5.71e-04	8	135	2	EFO_0800055
Disease	Autism Spectrum Disorders	TRIP12 JARID2 CNTNAP2 USH2A	6.37e-04	85	135	4	C1510586
Disease	nasopharyngeal neoplasm	PCLO EYS EPC1 CNTNAP2 HMGXB3	6.67e-04	151	135	5	EFO_0004252
Disease	complement factor D measurement	LPIN1 CNTNAP2 ZNF518B MBD2	8.93e-04	93	135	4	EFO_0020283
Disease	tauopathy (implicated_via_orthology)	MAP4 SH3KBP1	9.13e-04	10	135	2	DOID:680 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement	SOX6 BDP1 MAGI1 R3HDM2 MLLT10 CD163 LPIN1 CNTNAP2 HMGXB3 MERTK PHIP MTARC1	9.39e-04	904	135	12	EFO_0004736
Disease	autistic disorder (is_implicated_in)	MECP2 JARID2 CNTNAP2	9.44e-04	42	135	3	DOID:12849 (is_implicated_in)
Disease	sexual dysfunction	MDGA2 EPC1	1.11e-03	11	135	2	EFO_0004714
Disease	total blood protein measurement	DNAH3 RASA2 ZNF618 SH3KBP1 CPS1 SP140L MACF1 HYDIN	1.11e-03	449	135	8	EFO_0004536
Disease	phenylacetylglutamine measurement	SV2B SNTB1	1.33e-03	12	135	2	EFO_0021013
Disease	serum non-albumin protein measurement	RASA2 CPS1 MAST2 MECP2 BRF1 SP140L ULK4	1.41e-03	361	135	7	EFO_0004568
Disease	mental or behavioural disorder	TCF20 VPS13C NCKAP5 CNTNAP2 SNTB1	1.43e-03	179	135	5	EFO_0000677
Disease	Colorectal Carcinoma	DNAH3 TCOF1 ZNF217 XRCC1 ADAMTSL3 LPIN1 FAT1 BRF1 MKI67 PHIP	1.50e-03	702	135	10	C0009402
Disease	IGFBP-1 measurement	ZNF217 TGFBRAP1	1.57e-03	13	135	2	EFO_0005118
Disease	cirrhosis of liver	TSBP1 MTARC1	1.57e-03	13	135	2	EFO_0001422
Disease	visceral adipose tissue measurement	MDGA2 MAST2 TRIP12 ADCY9 GPR158 TSBP1 ULK4 EML1	1.72e-03	481	135	8	EFO_0004765
Disease	Squamous cell carcinoma of the head and neck	MERTK MAPK9 IL1RAP	1.76e-03	52	135	3	C1168401
Disease	physical activity measurement, body mass index	RASA2 MAST2 ADCY9 CNTNAP2	1.90e-03	114	135	4	EFO_0004340, EFO_0008002
Disease	body weight	RASA2 VPS13C MDGA2 MLLT10 CPS1 ADAMTSL3 TRIP12 ADCY9 EYS TBC1D31 PHF3 DGKK ULK4 LDLRAD4	1.96e-03	1261	135	14	EFO_0004338
Disease	Down syndrome (implicated_via_orthology)	DOP1B DYRK3	2.10e-03	15	135	2	DOID:14250 (implicated_via_orthology)
Disease	acute graft vs. host disease, donor genotype effect measurement	MDGA2 EYS	2.10e-03	15	135	2	EFO_0004599, EFO_0007892
Disease	lipid metabolism disorder (implicated_via_orthology)	LPIN1 HADHA	2.10e-03	15	135	2	DOID:3146 (implicated_via_orthology)
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	R3HDM2 CPS1 MACF1 MTARC1	2.35e-03	121	135	4	EFO_0008595, EFO_0020943
Disease	colorectal cancer (is_implicated_in)	XRCC1 FAT1 MKI67 MAPK9	2.35e-03	121	135	4	DOID:9256 (is_implicated_in)
Disease	cranial vault morphology measurement	VPS72 ADAMTSL3 DNM1P46 GPR158	2.35e-03	121	135	4	EFO_0009278
Disease	body surface area	CPS1 ADAMTSL3 TRIP12 ADCY9 TIAM2 LUZP1 ULK4 MACF1 MAPK9	2.88e-03	643	135	9	EFO_0022196
Disease	Disorder of eye	FREM1 EYS MERTK CPLANE1 USH2A	2.98e-03	212	135	5	C0015397
Disease	comparative body size at age 10, self-reported	MAGI1 RASA2 R3HDM2 ADAMTSL3 ADCY9 TSBP1 MBD2	3.28e-03	420	135	7	EFO_0009819
Disease	Seizures	ATN1 MECP2 NARS2 SLC8A3 MACF1	3.35e-03	218	135	5	C0036572
Disease	Congenital hernia of foramen of Morgagni	FREM1 IGF2R	3.38e-03	19	135	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	FREM1 IGF2R	3.38e-03	19	135	2	C0265700
Disease	hydrocephalus (implicated_via_orthology)	ULK4 HYDIN	3.38e-03	19	135	2	DOID:10908 (implicated_via_orthology)
Disease	serum homoarginine measurement	CPS1 ARG1	3.74e-03	20	135	2	EFO_0005421
Disease	Congenital diaphragmatic hernia	FREM1 IGF2R	4.12e-03	21	135	2	C0235833
Disease	cigarettes per day measurement	SOX6 MAGI1 ZNF618 MDGA2 ARG1 KCNC2 MBD2	4.12e-03	438	135	7	EFO_0006525
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	CPS1 MACF1 SOAT2 MTARC1	4.39e-03	144	135	4	EFO_0004611, EFO_0020943
Disease	colorectal carcinoma (is_implicated_in)	XRCC1 PTPRB	4.52e-03	22	135	2	DOID:0080199 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKVERSTDQVIKPVN	TPST1	281	O60507
IPSVKQEKRDGSSTN	EPC1	191	Q9H2F5
RKPGQTVNNKRVSAA	EPC2	546	Q52LR7
VKENATPTRNTISKV	BDP1	2076	A6H8Y1
QAARKPKVDGQVSET	CCNT2	261	O60583
IQKSPKGRAVSAIQD	ADGB	1211	Q8N7X0
RNVSVETRNVKPQGK	DNM1P46	16	Q6ZS02
EASTPKVNKQGRSEE	ATN1	61	P54259
PEGTQKVDATIVVKS	ARHGEF16	241	Q5VV41
KVKQVGVNPTSIDSV	APTX	71	Q7Z2E3
IRGTVSPQKQSAQKV	ANKRD36	1221	A6QL64
NTSRNASPEAKKVAI	ADGRG7	191	Q96K78
AAQQLTPKEATRTKV	DISP1	36	Q96F81
ASNPRTSLVQVKTKA	ATXN7L1	136	Q9ULK2
IVKNPRSVGKASEQL	ARG1	66	P05089
GKAVIINKTSNTRIP	R3HDM2	221	Q9Y2K5
TESQGKDSAKSVPRQ	REC114	166	Q7Z4M0
TVSLVGPSRNDQKKT	RASA2	196	Q15283
RPVSRVTNGTSNKKS	KIAA1107	276	Q9UPP5
KAVKTVRTPGAAANL	A1BG	441	P04217
PGKVNITVVAESKQS	OVOS1	721	Q6IE37
KAVDNGRPQKSSTTR	FAT1	1326	Q14517
RSKNGVVKDQPSDAA	MAPK9	366	P45984
EERKPKSGQSVQSFI	DGKK	1231	Q5KSL6
QERTVPDKVQGVSVS	PTPRB	726	P23467
IVKNKTEPVINGTSV	KCNC2	256	Q96PR1
INRTVGQTVKSPDKL	KATNBL1	51	Q9H079
IENSPFKVVVKSGRS	TRIM71	571	Q2Q1W2
TDKQSLKQAVGRITP	MATN3	141	O15232
GTQETRNTTKPKQES	MAGI1	1121	Q96QZ7
NTSAPDLKNVRSKVG	MAP4	926	P27816
KVKATNFRPNIVISG	MTARC1	231	Q5VT66
PGEAKFKSINTTVRV	EYS	1951	Q5T1H1
TVSKGVQINIKAIPS	MERTK	271	Q12866
NEQIVRVIKQTSPGK	LATS2	146	Q9NRM7
RFKENSVAVKVVQGP	MYO1A	1006	Q9UBC5
QTAGVEERTKSQKPL	GPR158	921	Q5T848
TRTLTVKVVGSPKNA	IL1RAP	226	Q9NPH3
VINSSAKAAKVQRAP	GABPA	286	Q06546
NKVNRTKVSVPDANG	DOP1B	2121	Q9Y3R5
TVKRQKQVSPSSEGH	DCLK3	621	Q9C098
ETKAEKVGNQTSVIP	EXOC3-AS1	36	Q8N2X6
VSSKGSVVKRNQQPV	HMGXB3	361	Q12766
PQTKQADIVRGESVK	PCLO	281	Q9Y6V0
RNPSGKQVATDKVAE	EVI5	11	O60447
SPVNAVLGTKTKAAV	FREM1	1831	Q5H8C1
LVSKSTERTGQKNPE	LPIN1	256	Q14693
VVQTANKTDSPSRKR	LPIN1	371	Q14693
NIPKRTDVKSQDVAV	EDC3	116	Q96F86
QKLDPAASVTGSKRQ	MKI67	2166	P46013
ATEGPVKAREVQKFT	MEAK7	116	Q6P9B6
QDQGKRSVPSEKLTT	MLKL	46	Q8NB16
VGNPAKKSTNIIVRA	MDGA2	316	Q7Z553
VTEKKLANSEPVGTQ	MACF1	5471	Q9UPN3
ASNVKTILPSKAVGV	NUTM1	136	Q86Y26
RQTASIFKQPVTKVT	MBD2	246	Q9UBB5
TGQEESKANIESKRP	ADAM30	766	Q9UKF2
PTQTISQGAIEKVKD	CPS1	1211	P31327
GESVRPKKINNITVS	HYDIN	5066	Q4G0P3
QKVKVAQRSPVDSGT	CENPF	3046	P49454
AVRKATQSPVTFQKG	CPLANE1	3066	Q9H799
QTAARTQGEKVEVTP	DNAH3	2531	Q8TD57
SQADNTSKKVTVRPG	FCGBP	71	Q9Y6R7
PVTKNVTVKSEGAIQ	CPD	851	O75976
TRNTVNTSLVGKQKP	CCDC66	121	A2RUB6
RLGTPKSVNKAVSQS	DLGAP5	636	Q15398
KGVQQKRPSEAQSVI	DENND6A	421	Q8IWF6
SSGDSNSVRVKINPK	ADCY9	21	O60503
QGTPKTSVKGVVQNR	CCP110	966	O43303
TSVKGVVQNRQKPSQ	CCP110	971	O43303
QSEGKKSREQPSVLS	LUZP1	461	Q86V48
NEPSLGRTQKSKSEV	ESCO2	226	Q56NI9
ARPVNKVIKSASATA	MAST2	1041	Q6P0Q8
ALENTSIKVGPARKN	MAST3	1036	O60307
KGDVAVVRINSPNSK	HADHA	46	P40939
AVRTNSPLQVKTGEK	CNTNAP2	481	Q9UHC6
GVRKETAVPATKSNI	EML1	116	O00423
NGPQKKSVDRSIQTV	DAZL	241	Q92904
ISVQKTPQKATTGRS	CD163	1031	Q86VB7
TTIDKVSGKRVVNPA	DYRK3	531	O43781
KVKQILGRSSSDPQA	HSPA14	66	Q0VDF9
NGSSRSTREKEPVQK	JARID2	226	Q92833
TRVNAAKNKTGAAPI	RPL27A	86	P46776
TTRPKAATSEGVQVK	MECP2	196	P51608
SKVVSSCQEKREPQG	IGF2R	1276	P11717
GTVNVFVKTQGSRKA	USH2A	2331	O75445
QVPESISNQKRGVKV	SNTB1	101	Q13884
VEPKRVRINTGKNTT	URI1	341	O94763
TSGRVQQPAKSRESK	TBC1D31	371	Q96DN5
RAKGTPEKVFTVSNI	SV2B	326	Q7L1I2
IQTQTPRKKTIGECS	TC2N	311	Q8N9U0
KVVTAAAQAKQRSPS	TCOF1	811	Q13428
VISSNPATTEVQRKK	NCKAP5	981	O14513
QVEVAEKVQKSSSPR	NBPF8	411	Q3BBV2
QIEVAEKVQKSSAPR	NBPF9	446	P0DPF3
QVEVAEKVQKSSAPR	NBPF10	446	Q6P3W6
QVEVAEKVQKSSSPR	NBPF11	446	Q86T75
QVEVAEKVQKSSAPR	NBPF14	106	Q5TI25
QVEVAEKVQKSSAPR	NBPF26	106	B4DH59
SVEVQGQLIKSPSKR	NARS2	91	Q96I59
VVEVPNSKDQRVKSA	PTCHD4	156	Q6ZW05
ANGTVATAAIQPKKV	SH3KBP1	196	Q96B97
TVNRATEKSVKTNGP	PTTG3P	66	Q9NZH4
PLQSVQVFGRKKTAT	RPS16	6	P62249
TVNRATEKSVKTNGP	PTTG2	66	Q9NZH5
NSSEIKKGRITPSQV	VPS8	1321	Q8N3P4
VSSLNKVSSQPEKRV	STARD9	2476	Q9P2P6
TVDIANNSTLGKPKR	SP140L	196	Q9H930
RVKKNAPQISDGSEV	SRBD1	66	Q8N5C6
SRTQEPSLGKQKVFI	SOAT2	91	O75908
TGIKNEKRGTSPVTQ	SOX6	401	P35712
QKVARLSDKTGPVAQ	MLLT10	1051	P55197
AAQESGTIPKKRQEV	AGPS	76	O00116
NVFGKKRANVVTTPS	ANKHD1	1526	Q8IWZ3
QVKARIPEVGAVTKQ	CNMD	136	O75829
QKTSPGRSVKEEAQN	RECQL5	951	O94762
AVQVVPTGNAATVRK	SLC35G4	121	P0C7Q5
QKSEEVGVQVFTKRP	TGFBRAP1	551	Q8WUH2
SRKQKASSEGTVPQV	UTP14C	471	Q5TAP6
QTNQSGKKAPASVVR	ZNF618	316	Q5T7W0
RQTVKQGSPTKDIEI	TIAM2	1576	Q8IVF5
RKPKVEVNTNSGEII	PHIP	1641	Q8WWQ0
VKKFSIVGTRSNDPV	TMOD1	226	P28289
VTPEVKRSNQGSKDL	SCEL	396	O95171
LQAKRVASVTKEDQP	ZNF592	291	Q92610
SIQVRTSKGNTPTQK	ZNF551	86	Q7Z340
ESLRTKQGPVVDVQK	WDFY4	786	Q6ZS81
VSTAKAGVKQPERSQ	PHF3	166	Q92576
AKETQILPRQTATGK	VPS13C	2076	Q709C8
NPKVNEKTVGVIVSR	TCF20	596	Q9UGU0
VSTQPAKKVATGEAL	BRF1	596	Q92994
KEQVETVPQATVKTG	NSD3	601	Q9BZ95
PSQKVTVTKLGQFRV	XRCC1	161	P18887
KGTAVVPFRATQEKN	ZNF217	41	O75362
GDVVNEKKRTPNETT	PNISR	476	Q8TF01
VNTPAGSSQKAREEK	VPS72	101	Q15906
RANTSERQKTGQVPK	TRIP12	51	Q14669
AQIKKSVSDVPRGQE	TSBP1	321	Q5SRN2
SVSDVPRGQESQVKK	TSBP1	326	Q5SRN2
PRRQESQVKKSQSGV	TSBP1	376	Q5SRN2
LKGPESQVKNTEVSV	TSBP1	451	Q5SRN2
ANVSGRKHPSTVQVK	ULK4	826	Q96C45
KQAPAENGAASRITK	ZNF541	716	Q9H0D2
LESNKTQRSSVGEKP	ZFP3	126	Q96NJ6
TSKVNIPVKVVSSNR	ZNF518B	556	Q9C0D4
KRTKANGTVQVVSPR	ADAMTSL3	1511	P82987
NNAESTIVPIKGKDR	LDLRAD4	286	O15165
TSQEREVTIKKPNGE	SLC8A3	106	P57103
ARNKAGTPVSELTKQ	N4BP1	236	O75113