Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	3-oxoacyl-[acyl-carrier-protein] synthase activity	FASN OXSM	6.46e-05	2	161	2	GO:0004315
GeneOntologyMolecularFunction	protein-ribulosamine 3-kinase activity	FN3KRP FN3K	6.46e-05	2	161	2	GO:0102193
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK3 OBSCN ALS2 TBC1D22B RABGAP1 DENND4C ARHGEF10L RASA4 RASA4B HERC2 GDPGP1 ACAP3 RGL4	2.45e-04	507	161	13	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK3 OBSCN ALS2 TBC1D22B RABGAP1 DENND4C ARHGEF10L RASA4 RASA4B HERC2 GDPGP1 ACAP3 RGL4	2.45e-04	507	161	13	GO:0030695
GeneOntologyMolecularFunction	low-affinity IgG receptor activity	FCGR3A FCGR3B	3.84e-04	4	161	2	GO:0019772
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH7 DYNC1H1	3.84e-04	18	161	3	GO:0008569
GeneOntologyMolecularFunction	carbon-oxygen lyase activity	ENOSF1 NTHL1 ACO2 FASN NAXD	5.30e-04	82	161	5	GO:0016835
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK3 OBSCN ALS2 DENND4C ARHGEF10L HERC2 GDPGP1 RGL4	5.85e-04	231	161	8	GO:0005085
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	GAA MGAM2	6.36e-04	5	161	2	GO:0004558
Domain	TF_fork_head_CS_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	2.63e-06	46	161	6	IPR030456
Domain	TF_fork_head_CS_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.00e-06	47	161	6	IPR018122
Domain	FH	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.85e-06	49	161	6	SM00339
Domain	FORK_HEAD_1	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.85e-06	49	161	6	PS00657
Domain	FORK_HEAD_2	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.85e-06	49	161	6	PS00658
Domain	Fork_head_dom	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.85e-06	49	161	6	IPR001766
Domain	FORK_HEAD_3	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.85e-06	49	161	6	PS50039
Domain	Forkhead	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.85e-06	49	161	6	PF00250
Domain	Ketoacyl-synt_C	FASN OXSM	7.39e-05	2	161	2	PF02801
Domain	PKS_Beta-ketoAc_synthase_dom	FASN OXSM	7.39e-05	2	161	2	IPR020841
Domain	Fructosamin_kin	FN3KRP FN3K	7.39e-05	2	161	2	PF03881
Domain	ketoacyl-synt	FASN OXSM	7.39e-05	2	161	2	PF00109
Domain	PKS_KS	FASN OXSM	7.39e-05	2	161	2	SM00825
Domain	B_KETOACYL_SYNTHASE	FASN OXSM	7.39e-05	2	161	2	PS00606
Domain	Ketoacyl_synth_AS	FASN OXSM	7.39e-05	2	161	2	IPR018201
Domain	Fructo-/Ketosamine-3-kinase	FN3KRP FN3K	7.39e-05	2	161	2	IPR016477
Domain	Ketoacyl_synth_N	FASN OXSM	7.39e-05	2	161	2	IPR014030
Domain	Ketoacyl_synth_C	FASN OXSM	7.39e-05	2	161	2	IPR014031
Domain	Dynein_HC_stalk	DNHD1 DNAH7 DYNC1H1	2.13e-04	14	161	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH7 DYNC1H1	2.13e-04	14	161	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH7 DYNC1H1	2.13e-04	14	161	3	PF08393
Domain	MT	DNHD1 DNAH7 DYNC1H1	2.13e-04	14	161	3	PF12777
Domain	-	RASA4 RASA4B	2.20e-04	3	161	2	4.10.1130.10
Domain	DHC_fam	DNHD1 DNAH7 DYNC1H1	2.65e-04	15	161	3	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH7 DYNC1H1	2.65e-04	15	161	3	PF03028
Domain	Dynein_heavy_dom	DNHD1 DNAH7 DYNC1H1	2.65e-04	15	161	3	IPR004273
Domain	Gal_mutarotase_N	GAA MGAM2	4.38e-04	4	161	2	IPR031727
Domain	NtCtMGAM_N	GAA MGAM2	4.38e-04	4	161	2	PF16863
Domain	-	PHLDB3 OBSCN APBB1 ALS2 RABGAP1 NIBAN2 ARHGEF10L RASA4 RASA4B SNTB1 ACAP3	5.94e-04	391	161	11	2.30.29.30
Domain	Reg_chr_condens	MARVELD1 ALS2 HERC2	8.58e-04	22	161	3	IPR000408
Domain	Glyco_hydro_31_AS	GAA MGAM2	1.08e-03	6	161	2	IPR030458
Domain	PH_dom-like	PHLDB3 OBSCN APBB1 ALS2 RABGAP1 NIBAN2 ARHGEF10L RASA4 RASA4B SNTB1 ACAP3	1.19e-03	426	161	11	IPR011993
Domain	Glyco_hydro_31	GAA MGAM2	1.51e-03	7	161	2	IPR000322
Domain	APC_su10/DOC_dom	HECTD3 HERC2	1.51e-03	7	161	2	IPR004939
Domain	DOC	HECTD3 HERC2	1.51e-03	7	161	2	PS51284
Domain	Glyco_hydro_31	GAA MGAM2	1.51e-03	7	161	2	PF01055
Domain	ANAPC10	HECTD3 HERC2	1.51e-03	7	161	2	PF03256
Domain	GLYCOSYL_HYDROL_F31_1	GAA MGAM2	1.51e-03	7	161	2	PS00129
Domain	APC10	HECTD3 HERC2	1.51e-03	7	161	2	SM01337
Pathway	REACTOME_SPERM_MOTILITY_AND_TAXES	CATSPERD CATSPER2 CATSPERG	5.11e-05	9	122	3	M26935
Pathway	REACTOME_SPERM_MOTILITY_AND_TAXES	CATSPERD CATSPER2 CATSPERG	5.11e-05	9	122	3	MM14548
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	1.04e-14	6	165	6	27092474
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	2.89e-13	8	165	6	8530406
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 MFSD13A FOXD4	2.97e-13	15	165	7	22045912
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	8.64e-13	9	165	6	12412011
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 CHRD FOXD4	5.23e-12	21	165	7	9449667
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 CHRD FOXD4	1.54e-11	24	165	7	29992973
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	1.74e-11	13	165	6	16884697
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	1.74e-11	13	165	6	7957066
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	5.03e-11	15	165	6	7689224
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	8.01e-11	16	165	6	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	8.01e-11	16	165	6	10208738
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	2.68e-10	19	165	6	9895322
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.82e-10	20	165	6	12812790
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	7.29e-10	22	165	6	17389379
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	1.30e-09	24	165	6	11820816
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	2.21e-09	26	165	6	15857913
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4	2.43e-09	5	165	4	12234674
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	4.52e-09	29	165	6	22972626
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 PHLDB3 MARVELD1 MFHAS1 POLR2A OBSCN TEP1 ABCA7 ST14 ARHGEF10L SLC52A3 FASN FAT1 DST MDN1 PSME4 CASKIN1 RRP12 MCM3AP HERC2 PLK3 DYNC1H1	1.51e-08	1105	165	22	35748872
Pubmed	Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	1.57e-07	11	165	4	12421752
Pubmed	Genome-scale study of transcription factor expression in the branching mouse lung.	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	8.18e-07	67	165	6	22711520
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	GPR35 ACO2 C5AR2 GDPD2 ABCA7 ADCY2 SLC39A13 SLC12A5 DST MAGED2 CD81 LSS FUCA2 ATP1A1 HERC2	1.32e-06	697	165	15	28298427
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ATRN EPRS1 POLR2A OR52L1 OBSCN PIDD1 CPT1B OR52N1 DST MDN1 MCM3AP PITPNM3 CHRD DYNC1H1 RGL4	2.57e-06	736	165	15	29676528
Pubmed	Diverse fates of paralogs following segmental duplication of telomeric genes.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	3.34e-06	22	165	4	15233989
Pubmed	A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa.	CATSPERD CATSPER2 CATSPERG	5.77e-06	8	165	3	21224844
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	EPRS1 MYO1C FASN RRP12 NUP210 ANKRD17 ATP1A1 HERC2	5.93e-06	202	165	8	33005030
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	EPRS1 MYO1C POLR2A FASN RRP12 ATP1A1 DYNC1H1	6.07e-06	144	165	7	35681168
Pubmed	Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2.	C5AR2 FCGR3A FCGR3B	8.63e-06	9	165	3	29599777
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	CYP4V2 OBSCN NEB TEP1 CLDN2 MFGE8 FASN NUP210	9.04e-06	214	165	8	22199357
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	EPRS1 HECTD3 FKRP SEMA4C FASN AARS2 MAGED2 GLE1 RRP12 NUP210 ANKRD17 LSS ATP1A1 DYNC1H1 GAA CAPN15	1.17e-05	942	165	16	31073040
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	EPRS1 MFHAS1 ACO2 CNTRL CPT1B CLCN6	1.73e-05	113	165	6	34474245
Pubmed	Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.	HK3 ACO2 H6PD SLC2A5 GAA ALDH7A1	1.82e-05	114	165	6	28245920
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	EPRS1 POGLUT3 MYO1C ACO2 H6PD F13A1 SLC39A13 FASN FAT1 CLCN6 AARS2 TMLHE NAXD CD81 LSS OXSM ATP1A1 CATSPERG VPS29 GAA	1.96e-05	1451	165	20	30550785
Pubmed	Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.	FCGR3A FCGR3B	2.24e-05	2	165	2	2521732
Pubmed	Effects on sperm morphology by alleles at the pink-eyed dilution locus in mice.	OCA2 HERC2	2.24e-05	2	165	2	863229
Pubmed	Associations of OCA2-HERC2 SNPs and haplotypes with human pigmentation characteristics in the Brazilian population.	OCA2 HERC2	2.24e-05	2	165	2	28081795
Pubmed	Single-cell analyses identify dysfunctional CD16+ CD8 T cells in smokers.	FCGR3A FCGR3B	2.24e-05	2	165	2	33163982
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	2.24e-05	2	165	2	11448776
Pubmed	Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.	FCGR3A FCGR3B	2.24e-05	2	165	2	26494566
Pubmed	Molecular characterization of radiation- and chemically induced mutations associated with neuromuscular tremors, runting, juvenile lethality, and sperm defects in jdf2 mice.	OCA2 HERC2	2.24e-05	2	165	2	10441737
Pubmed	Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.	FCGR3A FCGR3B	2.24e-05	2	165	2	23917248
Pubmed	Evidence for gene recombination in FCGR3 gene variants.	FCGR3A FCGR3B	2.24e-05	2	165	2	19320901
Pubmed	Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.	FCGR3A FCGR3B	2.24e-05	2	165	2	25966632
Pubmed	The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.	FCGR3A FCGR3B	2.24e-05	2	165	2	2967436
Pubmed	Pleiotropy in microdeletion syndromes: neurologic and spermatogenic abnormalities in mice homozygous for the p6H deletion are likely due to dysfunction of a single gene.	OCA2 HERC2	2.24e-05	2	165	2	7604002
Pubmed	The effects of mutant p-alleles on the reproductive system in mice.	OCA2 HERC2	2.24e-05	2	165	2	4435358
Pubmed	A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice.	OCA2 HERC2	2.24e-05	2	165	2	9689098
Pubmed	The expression of the genes for fructosamine-3-kinase and fructosamine-3-kinase-related protein appears to be constitutive and unaffected by environmental signals.	FN3KRP FN3K	2.24e-05	2	165	2	15381090
Pubmed	Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution.	POLR2A INTS10	2.24e-05	2	165	2	28027311
Pubmed	Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.	FCGR3A FCGR3B	2.24e-05	2	165	2	28355982
Pubmed	The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions.	FCGR3A FCGR3B	2.24e-05	2	165	2	7836402
Pubmed	Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.	FCGR3A FCGR3B	2.24e-05	2	165	2	25816339
Pubmed	The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcgammaRIIIa-48L/R/H polymorphism.	FCGR3A FCGR3B	2.24e-05	2	165	2	20664961
Pubmed	Fructosamine-6-phosphates are deglycated by phosphorylation to fructosamine-3,6-bisphosphates catalyzed by fructosamine-3-kinase (FN3K) and/or fructosamine-3-kinase-related-protein (FN3KRP).	FN3KRP FN3K	2.24e-05	2	165	2	16920277
Pubmed	FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene.	FCGR3A FCGR3B	2.24e-05	2	165	2	34108956
Pubmed	Linkage and association analysis of spectrophotometrically quantified hair color in Australian adolescents: the effect of OCA2 and HERC2.	OCA2 HERC2	2.24e-05	2	165	2	18528436
Pubmed	Tissue distribution and evolution of fructosamine 3-kinase and fructosamine 3-kinase-related protein.	FN3KRP FN3K	2.24e-05	2	165	2	15331600
Pubmed	The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential.	FCGR3A FCGR3B	2.24e-05	2	165	2	23770975
Pubmed	Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.	FCGR3A FCGR3B	2.24e-05	2	165	2	22290871
Pubmed	Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis.	FCGR3A FCGR3B	2.24e-05	2	165	2	20980704
Pubmed	Nucleotide sequence of a new Fc gamma receptor IIIB allele that codes for a neutrophil antigen.	FCGR3A FCGR3B	2.24e-05	2	165	2	11034564
Pubmed	A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color.	OCA2 HERC2	2.24e-05	2	165	2	18252222
Pubmed	Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.	OCA2 HERC2	2.24e-05	2	165	2	18252221
Pubmed	Some clues as to the regulation, expression, function, and distribution of fructosamine-3-kinase and fructosamine-3-kinase-related protein.	FN3KRP FN3K	2.24e-05	2	165	2	16037310
Pubmed	Genetic and molecular analysis of recessive alleles at the pink-eyed dilution (p) locus of the mouse.	OCA2 HERC2	2.24e-05	2	165	2	1495987
Pubmed	Separate promoters from proximal and medial control regions contribute to the natural killer cell-specific transcription of the human FcgammaRIII-A (CD16-A) receptor gene.	FCGR3A FCGR3B	2.24e-05	2	165	2	8940055
Pubmed	SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase.	SIRT3 FASN	2.24e-05	2	165	2	31677030
Pubmed	Gender is a major factor explaining discrepancies in eye colour prediction based on HERC2/OCA2 genotype and the IrisPlex model.	OCA2 HERC2	2.24e-05	2	165	2	23601698
Pubmed	FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.	FCGR3A FCGR3B	2.24e-05	2	165	2	27059607
Pubmed	Further insight into the global variability of the OCA2-HERC2 locus for human pigmentation from multiallelic markers.	OCA2 HERC2	2.24e-05	2	165	2	34795370
Pubmed	The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia.	CETP ABCB1	2.24e-05	2	165	2	16002074
Pubmed	Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.	FCGR3A FCGR3B	2.24e-05	2	165	2	25154742
Pubmed	A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms.	FCGR3A FCGR3B	2.24e-05	2	165	2	2525780
Pubmed	Variants at the OCA2/HERC2 locus affect time to first cutaneous squamous cell carcinoma in solid organ transplant recipients collected using two different study designs.	OCA2 HERC2	2.24e-05	2	165	2	28456133
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	2.24e-05	2	165	2	16041389
Pubmed	Genotyping of five single nucleotide polymorphisms in the OCA2 and HERC2 genes associated with blue-brown eye color in the Japanese population.	OCA2 HERC2	2.24e-05	2	165	2	19472299
Pubmed	FcgammaRIII expression on cultured human keratinocytes and upregulation by interferon-gamma.	FCGR3A FCGR3B	2.24e-05	2	165	2	12445195
Pubmed	Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation.	POLR2A PLK3	2.24e-05	2	165	2	22549466
Pubmed	Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.	FCGR3A FCGR3B	2.24e-05	2	165	2	2526846
Pubmed	B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.	FCGR3A FCGR3B	2.24e-05	2	165	2	18292508
Pubmed	Structure of a mammalian sperm cation channel complex.	CATSPERD CATSPER2 CATSPERG	2.90e-05	13	165	3	34225353
Pubmed	Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.	SIRT3 HERC2 SNTB1 DYNC1H1	4.31e-05	41	165	4	19343720
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	ENOSF1 MYO1C F2RL3 C5AR2 ALS2 NUDT9 NEB DNAH7 F13A1 PDLIM5 MFGE8 FAT1 DST MDN1 NAXD CD81 FUCA2 RIMS2	4.61e-05	1293	165	18	15342556
Pubmed	Fc gamma receptor genes as risk markers for localized aggressive periodontitis in African-Americans.	FCGR3A FCGR3B	6.69e-05	3	165	2	12027254
Pubmed	Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling.	ABCB1 ATP1A1	6.69e-05	3	165	2	26158764
Pubmed	Analysis of Fc gamma RIII (CD16) membrane expression and association with CD3 zeta and Fc epsilon RI-gamma by site-directed mutation.	FCGR3A FCGR3B	6.69e-05	3	165	2	1825220
Pubmed	Polymorphism of Fc gamma RIIa may affect the efficacy of gamma-globulin therapy in Kawasaki disease.	FCGR3A FCGR3B	6.69e-05	3	165	2	16133986
Pubmed	Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.	FCGR3A FCGR3B	6.69e-05	3	165	2	28427365
Pubmed	Different stabilities of the structurally related receptors for IgE and IgG on the cell surface are determined by length of the stalk region in their alpha-chains.	FCGR3A FCGR3B	6.69e-05	3	165	2	16709862
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	6.69e-05	3	165	2	25637021
Pubmed	Patterns of low-affinity immunoglobulin receptor polymorphisms in stroke and homozygous sickle cell disease.	FCGR3A FCGR3B	6.69e-05	3	165	2	11835346
Pubmed	FcgammaRIIa, IIIa and IIIb gene polymorphisms in Behçet's disease: do they have any clinical implications?	FCGR3A FCGR3B	6.69e-05	3	165	2	19026120
Pubmed	Abnormal spermiogenesis in two pink-eyed sterile mutants in the mouse.	OCA2 HERC2	6.69e-05	3	165	2	5565073
Pubmed	Immunoglobulin G fc-receptor (FcgammaR) IIA, IIIA, and IIIB polymorphisms related to disease severity in rheumatoid arthritis.	FCGR3A FCGR3B	6.69e-05	3	165	2	12064825
Pubmed	FcgammaRIIA, FcgammaRIIIA and FcgammaRIIIB polymorphisms in Spanish patients with systemic lupus erythematosus.	FCGR3A FCGR3B	6.69e-05	3	165	2	12121275
Pubmed	Interactions between HERC2, OCA2 and MC1R may influence human pigmentation phenotype.	OCA2 HERC2	6.69e-05	3	165	2	19208107
Pubmed	Infectious complications after chemotherapy and stem cell transplantation in multiple myeloma: implications of Fc gamma receptor and myeloperoxidase promoter polymorphisms.	FCGR3A FCGR3B	6.69e-05	3	165	2	18452102
Pubmed	Fcgamma receptor polymorphisms in relation to periodontitis.	FCGR3A FCGR3B	6.69e-05	3	165	2	12834496
Pubmed	Fc gamma RIIa, IIIa and IIIb polymorphisms in Turkish children susceptible to recurrent infectious diseases.	FCGR3A FCGR3B	6.69e-05	3	165	2	16550341
Pubmed	Association of the Fc gamma receptor IIA-R/R131 genotype with myasthenia gravis in Dutch patients.	FCGR3A FCGR3B	6.69e-05	3	165	2	14597109
Cytoband	9q21.11	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3	4.10e-06	30	165	4	9q21.11
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	DNHD1 OR52L1 APBB1 PIDD1 OR52N1 SIRT3 OR52L2P OR52H1 OR52N5 CD81	4.13e-05	564	165	10	chr11p15
Cytoband	11p15.4	DNHD1 OR52L1 OR52N1 OR52L2P OR52H1 OR52N5	9.13e-05	200	165	6	11p15.4
Cytoband	1p36	H6PD CLCN6 CLCNKA	6.58e-04	47	165	3	1p36
Cytoband	Ensembl 112 genes in cytogenetic band chr3q11	OR5H15 OR5H14 OR5H1	9.88e-04	54	165	3	chr3q11
GeneFamily	Cation channels sperm associated	CATSPERD CATSPER2 CATSPERG	6.00e-06	7	102	3	186
GeneFamily	Olfactory receptors, family 52	OR52L1 OR52N1 OR52L2P OR52H1 OR52N5	8.11e-06	49	102	5	165
GeneFamily	Chloride voltage-gated channels	CLCN6 CLCNKA	1.38e-03	10	102	2	302
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA4 RASA4B	1.38e-03	10	102	2	830
Coexpression	GSE11884_WT_VS_FURIN_KO_NAIVE_CD4_TCELL_DN	CATSPERD MFHAS1 POLR2A TBC1D22B ABCA7 ADCY2 DST LINGO4	1.50e-06	128	164	8	M410
Coexpression	GSE14308_TH17_VS_NAIVE_CD4_TCELL_DN	PDSS2 WDR64 MFHAS1 POLR2A ARL13A ABCA7 CASKIN1 DYNC1H1 CAPN15	4.80e-06	199	164	9	M3384
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_APOE_POS_M2_MACROPHAGE_CELL	HK3 HECTD3 MFHAS1 CETP WDR81 RAB42 NIBAN2 DENND4C HSD3B7 DST FCGR3A FCGR3B IL4I1	1.01e-05	476	164	13	M45717
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	DNHD1 MFHAS1 APBB1 WDR81 CPT1B F13A1 ARHGEF10L FCGR3B CATSPERG ECE2	3.71e-09	199	164	10	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK3 ST14 AK8 SLC2A5 SLC12A5 CD81 FUCA2 ECE2	3.31e-07	178	164	8	30d2b54462fd16222ad2e3806be6143e834b29e0
ToppCell	facs-BAT-Fat-3m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 NIBAN2 TEP1 F13A1 ARHGEF10L FCGR3B RASA4	3.55e-06	172	164	7	5f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	HK3 NIBAN2 ARHGEF10L FCGR3A IL4I1 GAA FOXD4	3.68e-06	173	164	7	bba8265a58f8f5659dc7b9da2fe27b15033fce34
ToppCell	wk_15-18-Hematologic-Myeloid-aDC_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L1 FOXD4L3 IL4I1 FOXD4	4.28e-06	177	164	7	ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCell	droplet-Spleen-nan-24m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 NIBAN2 F13A1 ARHGEF10L FCGR3A FCGR3B MFSD13A	4.28e-06	177	164	7	5f20a1a875d6f85ec07b097e6afdb07c2f8f88ff
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCA2 CPT1B AK8 CLDN2 CLCNKA SLC4A5 SNTB1	4.78e-06	180	164	7	729f0d7af573c7796d8e28e6eec3af2fc0bd33a2
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCA2 CPT1B AK8 CLDN2 CLCNKA SLC4A5 SNTB1	4.78e-06	180	164	7	9ef79a7c60227e352ac166c7274adb31f585f5ca
ToppCell	droplet-Marrow-nan-21m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F13A1 SIRT3 FASN RASA4 NUP210 GAA ECE2	6.36e-06	188	164	7	f94dc08948a823f47882aa0714b9a60de4ff85d5
ToppCell	droplet-Marrow-nan-21m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F13A1 SIRT3 FASN RASA4 NUP210 GAA ECE2	6.36e-06	188	164	7	7c67330c36696a7772364af67c6df4e6406fa742
ToppCell	390C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HK3 RAB42 ACOT4 ARHGEF10L HSD3B7 FCGR3A GAA	7.55e-06	193	164	7	c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB DENND4C SLC2A5 DST PRSS53 ATP1A1 GAA	7.81e-06	194	164	7	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_interstitial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RAB42 OR5H14 CPT1B CLCN6 TMLHE ZFP92 IL4I1	8.35e-06	196	164	7	e12fc1bfeb42457b204d582d3e19f01e2345cb6a
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Transverse / Region, Cell class and subclass	WDR81 F13A1 ARHGEF10L SLC12A5 FCGR3A FCGR3B ECE2	9.22e-06	199	164	7	facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCell	Transverse-(6)_Macrophage-(61)_LYVE1_Macrophage\|Transverse / shred on region, Cell_type, and subtype	WDR81 F13A1 ARHGEF10L SLC12A5 FCGR3A FCGR3B ECE2	9.22e-06	199	164	7	dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCell	Mild-Myeloid-Macrophages-FCN1-SPP1+\|Mild / Condition, Lineage, Cell class and cell subclass	RAB42 ST14 FCGR3A CD81 FUCA2 IL4I1 GAA	9.53e-06	200	164	7	e5afd8e2cb2c63899d49fe17011f474d20bb06ea
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK3 GPR152 WDR81 ST14 SLC2A5 PLK3 GAA	9.53e-06	200	164	7	80e0483d5ab0c6213aae0ec62619f57e6ec0e4c2
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid-macrophage\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 C5AR2 WDR81 AK8 F13A1 FCGR3B	2.22e-05	153	164	6	4b999892fb797e9f0d391630094f466463299d57
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 C5AR2 WDR81 AK8 F13A1 FCGR3B	2.22e-05	153	164	6	e426db29e4ba83e7930dc88c74fc975b177c9540
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 C5AR2 WDR81 AK8 F13A1 FCGR3B	2.22e-05	153	164	6	668eacd76aad6054bd7d57e3af0b122c2443465f
ToppCell	facs-Lung-EPCAM-24m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 TSPOAP1 C5AR2 FCGR3B PLK3 FOXD4	2.57e-05	157	164	6	d2cb261a9ee2c90e2e0fc656bd6413fbccb465fc
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 TSPOAP1 C5AR2 FCGR3B PLK3 FOXD4	2.57e-05	157	164	6	350069e4d2dbddc82e813e2a2cc43032daa23605
ToppCell	facs-MAT-Fat-18m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 C5AR2 F13A1 FCGR3A FCGR3B	2.85e-05	160	164	6	bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NIBAN2 ARHGEF10L FCGR3A CD81 IL4I1 FOXD4	2.85e-05	160	164	6	6d941e584360975e1fdbb2fc67af8e31f18759d8
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4V2 OBSCN MDGA2 GCNT4 MAGED2 FUCA2	3.06e-05	162	164	6	ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCell	facs-MAT-Fat-18m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 C5AR2 F13A1 FCGR3A FCGR3B	3.51e-05	166	164	6	9116be2805c34881debb999d8417e43832fcf2f2
ToppCell	droplet-Spleen-nan-18m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 F13A1 ARHGEF10L FCGR3A FCGR3B PITPNM3	3.51e-05	166	164	6	e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCell	facs-SCAT-Fat-3m-Myeloid-myeloid_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 C5AR2 TEP1 F13A1 FCGR3A FCGR3B	3.51e-05	166	164	6	8395c74db8e4e54af97a3f2b75cb75171140ec31
ToppCell	facs-SCAT-Fat-3m-Myeloid\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 C5AR2 TEP1 F13A1 FCGR3A FCGR3B	3.51e-05	166	164	6	76807edc5620514b53a14be354b84c54c112b8f9
ToppCell	facs-MAT-Fat-18m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 C5AR2 F13A1 FCGR3A FCGR3B	3.51e-05	166	164	6	5c2667da79935f3d4b1edbfe7a10e7dbc2fa3ad0
ToppCell	facs-SCAT-Fat-3m-Myeloid-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 C5AR2 TEP1 F13A1 FCGR3A FCGR3B	3.51e-05	166	164	6	645b842b94b8d2f4b26c2623f8589f56bd782c26
ToppCell	droplet-Spleen-nan-18m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 F13A1 ARHGEF10L FCGR3A FCGR3B PITPNM3	3.51e-05	166	164	6	3ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCell	droplet-Spleen-nan-18m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 F13A1 ARHGEF10L FCGR3A FCGR3B PITPNM3	3.51e-05	166	164	6	f751cbd01d4978ded7755874ab60504f6291afd7
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 F13A1 ARHGEF10L HSD3B7 FCGR3A FCGR3B	4.01e-05	170	164	6	7cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 F13A1 ARHGEF10L HSD3B7 FCGR3A FCGR3B	4.01e-05	170	164	6	db7cee7e518debb2cbe9eeae05d47e14b69cb8e3
ToppCell	facs-BAT-Fat-18m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 F13A1 ARHGEF10L FCGR3A FCGR3B ATP1A1	4.28e-05	172	164	6	36fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLR2A GDPD2 CLDN2 DENND4C PRSS53 PITPNM3	4.56e-05	174	164	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 NIBAN2 TEP1 F13A1 ARHGEF10L FCGR3B	4.71e-05	175	164	6	69b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR35 NIBAN2 TEP1 F13A1 ARHGEF10L FCGR3B	4.71e-05	175	164	6	4f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCell	wk_20-22-Hematologic-Myeloid-aDC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FOXD4L6 FOXD4L4 FOXD4L1 FOXD4L3 IL4I1 FOXD4	5.18e-05	178	164	6	fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POGLUT3 ISYNA1 CNTRL B9D2 RIMS2 WDR62	5.34e-05	179	164	6	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	POGLUT3 ISYNA1 CNTRL B9D2 RIMS2 WDR62	5.34e-05	179	164	6	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	droplet-Kidney-nan-18m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMIM24 CLDN2 PSME4 ATP1A1 SARDH PLK3	6.22e-05	184	164	6	e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCA2 CPT1B CLDN2 CLCNKA SLC4A5 SNTB1	6.61e-05	186	164	6	d4e327cc1d7b618654ffe0ff6475fe8e8cc5cb01
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	HK3 C5AR2 RAB42 F13A1 ARHGEF10L FCGR3A	7.01e-05	188	164	6	d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell	NS-critical-d_16-33-Myeloid-Monocyte-derived_DC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CETP RAB42 SLC12A5 FCGR3A CD81 IL4I1	7.01e-05	188	164	6	08eb1e4b719af53c52895557523d0a1b7421d849
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_large-bowel / Manually curated celltypes from each tissue	HK3 C5AR2 RAB42 F13A1 ARHGEF10L FCGR3A	7.01e-05	188	164	6	0bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell	(2)_NK/T-(210)_NKT_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	TSPOAP1 H6PD FN3K ABCB1 FCGR3A WDR62	7.22e-05	189	164	6	fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell	(2)_NK/T-(21)_NKT_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	TSPOAP1 H6PD FN3K ABCB1 FCGR3A WDR62	7.22e-05	189	164	6	b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCell	390C-Myeloid-Macrophage-FABP4+_Macrophage_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	HK3 RAB42 ACOT4 ARHGEF10L HSD3B7 GAA	7.22e-05	189	164	6	3b5e1a8d5c1e1fa2124f64f212e9c6b8f1b7d7da
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|IPF / Disease state, Lineage and Cell class	DST PSME4 FCGR3A CD81 SNTB1 GAA	7.43e-05	190	164	6	e539ebc0f4c5ee5dba86c614387be7d91338ad47
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	DENND4C DST PSME4 CD81 SNTB1 GAA	7.43e-05	190	164	6	9fc763d65470ba8858b973689c4d4358faab7dd3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK3 UGT3A1 GPR152 SLC2A5 FCGR3A GAA	7.65e-05	191	164	6	7d00796459f4ff0ab7f06a8379b2d34e76b078b2
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F2RL3 SIRT3 HSD3B7 DST MAGED2 GAA	7.87e-05	192	164	6	959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCell	CTRL-Myeloid-Alveolar_Macrophage\|Myeloid / Disease state, Lineage and Cell class	DENND4C DST FCGR3A CD81 SNTB1 GAA	8.10e-05	193	164	6	80871d963c23a6befe58e5e60b7f7d1a1b227ce2
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB DENND4C SLC2A5 DST PRSS53 GAA	8.10e-05	193	164	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB DENND4C SLC2A5 DST PRSS53 GAA	8.10e-05	193	164	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ENOSF1 MFHAS1 DNAH7 ARHGEF10L FAT1 ATP1A1	8.10e-05	193	164	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	CTRL-Myeloid-Alveolar_Macrophage\|CTRL / Disease state, Lineage and Cell class	DENND4C DST FCGR3A CD81 SNTB1 GAA	8.33e-05	194	164	6	be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCell	390C-Myeloid-Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HK3 RAB42 ARHGEF10L HSD3B7 FCGR3A GAA	8.57e-05	195	164	6	ba494be431916d43c1d480f65bed674c0722c710
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HK3 CETP RAB42 FCGR3A IL4I1 GAA	8.57e-05	195	164	6	5a7c74f96f213c504abd65e751800da7e03e47d9
ToppCell	CTRL\|World / Disease state, Lineage and Cell class	DENND4C DST FCGR3A CD81 SNTB1 GAA	8.57e-05	195	164	6	cad77cdc6e0aa0875eff5ecd3805a6cf056d729d
ToppCell	droplet-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACO2 MFGE8 DST CD81 ATP1A1 SARDH	8.82e-05	196	164	6	b880c9665d42c76ea1971d4e49d7ecf72fcfafb6
ToppCell	Bronchial_Brush-Immune-Luminal_Macrophages\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	RAB42 ARHGEF10L HSD3B7 FCGR3A CD81 SNTB1	9.32e-05	198	164	6	77f41f0e0895b7c732bab1fd2e047f2ed31cbd9d
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SMIM24 RAB42 AK8 SLC2A5 IL4I1 GAA	9.32e-05	198	164	6	243109377d62d20c69e9d1fedc252156e90cda1e
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	MFHAS1 ABCB1 MDN1 RASA4 RRP12 RASA4B	9.32e-05	198	164	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HK3 ACOT4 HSD3B7 FCGR3A CD81 GAA	9.32e-05	198	164	6	d18270f45f170a8da6105f1c212cada6aab75412
ToppCell	BAL-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	HK3 ARHGEF10L HSD3B7 FCGR3A CD81 GAA	9.58e-05	199	164	6	4518ffa51ead9da1ddf07bf048b18602e50f0f84
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ERICH3 NEK10 DNAH7 ADCY2 AK8 XRRA1	9.58e-05	199	164	6	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_interstitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HK3 OVCH1 SLC12A5 FCGR3A IL4I1 MGAM2	9.58e-05	199	164	6	4b6d49b96bfcd6604b082bab620ae03276520885
ToppCell	PBMC-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	HK3 NIBAN2 F13A1 ARHGEF10L FCGR3A SNTB1	9.58e-05	199	164	6	ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell	Sigmoid-(6)_Macrophage-(61)_LYVE1_Macrophage\|Sigmoid / shred on region, Cell_type, and subtype	HK3 MARVELD1 C5AR2 F13A1 ARHGEF10L FCGR3A	9.85e-05	200	164	6	bc0280d52e4edc2c5edf4ead164a1c7cf3fccd60
ToppCell	Sigmoid-Macrophage-LYVE1_Macrophage\|Sigmoid / Region, Cell class and subclass	HK3 MARVELD1 C5AR2 F13A1 ARHGEF10L FCGR3A	9.85e-05	200	164	6	851a1b372ddbec522829069e69ed36a1f4832131
ToppCell	(61)_LYVE1_Macrophage\|World / shred on Cell_type and subtype	HK3 MARVELD1 C5AR2 F13A1 ARHGEF10L FCGR3A	1.16e-04	206	164	6	711e961a9a03bfd2f0958bd14f25f7f207a2f2b5
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CYP4V2 UGT3A1 SLC2A5 RASA4 ATP1A1	2.00e-04	145	164	5	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP4V2 UGT3A1 ITIH2 HSD3B7 SARDH	2.13e-04	147	164	5	00619115b9a1ec2b967c2992043b41974ece63c4
ToppCell	Immune_cells-Monocytes\|World / Lineage and Cell class	GPR35 TEP1 AK8 F13A1 FCGR3B	2.20e-04	148	164	5	e8037e831a6b11b06073b4e76684eb61308822f1
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPR35 F13A1 SEMA4C RASA4 MGAM2	2.41e-04	151	164	5	0b6b37734430918378ed94e40877f0c4ae9b25ec
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPR35 F13A1 SEMA4C RASA4 MGAM2	2.41e-04	151	164	5	30225a1a7800b0ae19e16ac164f561379eedb99d
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SMIM24 ISYNA1 TSPOAP1 NUDT8 RASA4B	2.41e-04	151	164	5	8ffd71d847fe1aeebe7f43c4b6ca73efb19d6041
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ISYNA1 MFHAS1 SIRT3 ABCB1 LINGO4	2.49e-04	152	164	5	6aad62b5b5ad2f78c6600f37960338d40628a439
ToppCell	facs-Marrow-T-cells-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEP1 F13A1 ARHGEF10L FCGR3A CHRD	2.49e-04	152	164	5	d279592c501fca9cb474ad916fea32282e6969cb
ToppCell	facs-Marrow-T-cells-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEP1 F13A1 ARHGEF10L FCGR3A CHRD	2.49e-04	152	164	5	3b59143b2b4ee24eb6378f87ff568124193256e9
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	HK3 RAB42 FCGR3A OR52H1 GAA	2.56e-04	153	164	5	e0fbbfd4d13031412e0b985322c8b99c56eb7af5
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	HK3 PAQR4 C5AR2 F13A1 FCGR3B	2.72e-04	155	164	5	15bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SMIM24 DOCK3 ISYNA1 NTHL1 SLC52A3	2.80e-04	156	164	5	96747447ba7dc2c10079cee44394b19ce60b2f41
ToppCell	facs-Lung-24m-Hematologic-myeloid-neutrophil\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HK3 C5AR2 FCGR3B PLK3 FOXD4	2.89e-04	157	164	5	e96241db2b5ff52b230e3e33207e7bb968900cab
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 F13A1 FCGR3A FCGR3B	2.89e-04	157	164	5	c3451b33780499fd62672e7cd71c7e8cb6ccc2c5
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 F13A1 FCGR3A FCGR3B	2.89e-04	157	164	5	92cd58b62e46b93f90e05657fd201404ccae6ddb
ToppCell	facs-Lung-24m-Hematologic-myeloid-neutrophil-neutrophil\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HK3 C5AR2 FCGR3B PLK3 FOXD4	2.89e-04	157	164	5	07a0f8d29a3111be670eae030a91474465eba734
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 F13A1 FCGR3A FCGR3B	2.89e-04	157	164	5	042129d1b514dc4ed8a5f45b52d9c73cf4807636
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D22B H6PD RRP12 PITPNM3 FUCA2	2.89e-04	157	164	5	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	facs-Lung-EPCAM-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 TEP1 F13A1 FCGR3B	2.97e-04	158	164	5	ef5feb48161c339c7b71c576bdda61479d29dfac
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 TEP1 F13A1 FCGR3B	2.97e-04	158	164	5	c6e64b9b3342e37d54baadae8fb7dfb5d246e4cf
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 C5AR2 FCGR3B PLK3 FOXD4	2.97e-04	158	164	5	d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 C5AR2 FCGR3B PLK3 FOXD4	2.97e-04	158	164	5	ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCell	facs-Lung-EPCAM-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 C5AR2 FCGR3B PLK3 FOXD4	3.06e-04	159	164	5	baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 C5AR2 FCGR3B PLK3 FOXD4	3.06e-04	159	164	5	9eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCell	facs-Lung-nan-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 GPR35 C5AR2 FCGR3B FOXD4	3.06e-04	159	164	5	836c4b5f9a714ffb5a449087ebefdbb37dd3a2a9
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB SLC39A13 ABCB1 RASA4 CHRD	3.06e-04	159	164	5	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	AMH FKRP H6PD TEP1 ARHGEF10L CLCN6 CATSPER2 RIMS2 WDR62 CAPN15	1.27e-06	194	161	10	4763_DN
Drug	quinaldic acid	CETP ACO2 ABCB1 OXSM	5.34e-06	17	161	4	CID000007124
Drug	A-FN	ENOSF1 PDLIM5 FCGR3A FCGR3B	8.59e-06	19	161	4	CID005287635
Drug	valdecoxib	ATRN ISYNA1 ZAN ACOT4 CMAS SIRT3 CLDN2 DENND4C SLC2A5 ABCB1 FASN PSME4 CD81 LSS ATP1A1 SARDH GAA	1.11e-05	705	161	17	ctd:C406224
Disease	SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 1	OCA2 HERC2	2.47e-05	2	147	2	227220
Disease	SKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES	OCA2 HERC2	2.47e-05	2	147	2	cv:C1856895
Disease	level of low affinity immunoglobulin gamma Fc region receptor III-A in blood serum	FCGR3A FCGR3B	2.47e-05	2	147	2	OBA_2040305
Disease	Lupus Vasculitis, Central Nervous System	FCGR3A FCGR3B	7.37e-05	3	147	2	C0752332
Disease	Lupus Meningoencephalitis	FCGR3A FCGR3B	7.37e-05	3	147	2	C0752334
Disease	Neuropsychiatric Systemic Lupus Erythematosus	FCGR3A FCGR3B	7.37e-05	3	147	2	C0752335
Disease	blood pressure, response to thiazide, response to beta blocker	OR5H14 OR5H1	7.37e-05	3	147	2	EFO_0004325, EFO_0007766, EFO_0007981
Disease	suntan, skin pigmentation	OCA2 HERC2	1.47e-04	4	147	2	EFO_0003784, EFO_0004279
Disease	glucose-6-phosphate measurement	FN3KRP FN3K	1.47e-04	4	147	2	EFO_0010485
Disease	Bartter syndrome	CLCNKA MAGED2	3.65e-04	6	147	2	cv:C0004775
Disease	low affinity immunoglobulin gamma Fc region receptor II-a/b measurement	FCGR3A FCGR3B	5.09e-04	7	147	2	EFO_0008211
Disease	microcephaly (implicated_via_orthology)	WDR81 AARS2 WDR62	5.40e-04	32	147	3	DOID:10907 (implicated_via_orthology)
Disease	allergic rhinitis (is_implicated_in)	ABCB1 FCGR3A	6.77e-04	8	147	2	DOID:4481 (is_implicated_in)
Disease	chemotherapy-induced alopecia, response to docetaxel trihydrate	ABCB1 SLC52A3	6.77e-04	8	147	2	EFO_0005400, GO_1902519
Disease	asparaginase-induced acute pancreatitis	NEB PDLIM5	8.67e-04	9	147	2	EFO_1001507
Disease	lactosyl-N-nervonoyl-sphingosine (d18:1/24:1) measurement	CETP ABCA7	8.67e-04	9	147	2	EFO_0800517
Disease	plexin-B2 measurement	FCGR3A FCGR3B	8.67e-04	9	147	2	EFO_0021867
Disease	Bone Diseases	SLC39A13 ALDH7A1	1.08e-03	10	147	2	C0005940
Disease	hair colour measurement, eye colour measurement, skin pigmentation measurement	OCA2 HERC2	1.08e-03	10	147	2	EFO_0007009, EFO_0007822, EFO_0009764
Disease	granulosa cell tumor (is_marker_for)	AMH ST14	1.32e-03	11	147	2	DOID:2999 (is_marker_for)
Disease	pigmentation disease (is_implicated_in)	OCA2 HERC2	1.32e-03	11	147	2	DOID:10123 (is_implicated_in)
Disease	epilepsy (implicated_via_orthology)	ABCB1 SLC12A5 ATP1A1 DYNC1H1 ALDH7A1	1.38e-03	163	147	5	DOID:1826 (implicated_via_orthology)
Disease	left ventricular systolic function measurement	MYO1C OBSCN CLCNKA	1.38e-03	44	147	3	EFO_0008206
Disease	Malformations of Cortical Development	DYNC1H1 WDR62	2.16e-03	14	147	2	C1955869
Disease	low affinity immunoglobulin gamma Fc region receptor III-B measurement	FCGR3A FCGR3B	2.16e-03	14	147	2	EFO_0008212
Disease	Cortical Dysplasia	DYNC1H1 WDR62	2.16e-03	14	147	2	C0431380
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 ANKRD17	2.16e-03	14	147	2	EFO_0004611, EFO_0008589
Disease	GDH/6PGL endoplasmic bifunctional protein measurement	H6PD OVCH1	2.16e-03	14	147	2	EFO_0801619
Disease	triglycerides in medium VLDL measurement	TDRD15 CETP INTS10	2.63e-03	55	147	3	EFO_0022155
Disease	free cholesterol to total lipids in large HDL percentage	TDRD15 CETP SLC12A5	2.77e-03	56	147	3	EFO_0022279
Disease	Colorectal Carcinoma	EVC2 HK3 NTHL1 OBSCN OTOP2 ARHGEF10L ABCB1 SLC12A5 FAT1 MCM3AP	2.80e-03	702	147	10	C0009402
Disease	temporal arteritis (is_implicated_in)	MFGE8 FCGR3A	2.83e-03	16	147	2	DOID:13375 (is_implicated_in)
Disease	Malignant neoplasm of breast	HK3 ACO2 OBSCN OCA2 H6PD SLC2A5 ABCB1 MFGE8 FASN MAGED2 SLC10A6 OXSM HERC2	2.85e-03	1074	147	13	C0006142
Disease	Hypertrophic Cardiomyopathy	OBSCN FASN GAA	2.91e-03	57	147	3	C0007194
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	FCGR3A FCGR3B	3.19e-03	17	147	2	EFO_0021969
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	TDRD15 CETP	3.19e-03	17	147	2	EFO_0022232
Disease	phospholipids in VLDL measurement	TDRD15 CETP INTS10	3.21e-03	59	147	3	EFO_0022301
Disease	uterine fibroid	POGLUT3 HK3 NEK10 SIRT3 PDLIM5	3.27e-03	199	147	5	EFO_0000731
Disease	total lipids in VLDL measurement	TDRD15 CETP INTS10	3.37e-03	60	147	3	EFO_0022314
Disease	triglycerides in small VLDL measurement	TDRD15 CETP INTS10	3.53e-03	61	147	3	EFO_0022145
Disease	free cholesterol in very large VLDL measurement	TDRD15 CETP INTS10	3.53e-03	61	147	3	EFO_0022274
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	TDRD15 CETP	3.58e-03	18	147	2	EFO_0008317, EFO_0008589
Disease	phospholipids in large VLDL measurement	TDRD15 CETP INTS10	3.70e-03	62	147	3	EFO_0022169
Disease	phospholipids in very large VLDL measurement	TDRD15 CETP INTS10	3.70e-03	62	147	3	EFO_0022299
Disease	skin sensitivity to sun	OCA2 HERC2	3.99e-03	19	147	2	EFO_0004795
Disease	Hypertriglyceridemia	TDRD15 CETP	3.99e-03	19	147	2	EFO_0004211
Disease	cholesterol in large VLDL measurement	TDRD15 CETP INTS10	4.22e-03	65	147	3	EFO_0021902
Disease	cholesterol in very large VLDL measurement	TDRD15 CETP INTS10	4.22e-03	65	147	3	EFO_0022230
Disease	total lipids in small VLDL	TDRD15 CETP INTS10	4.60e-03	67	147	3	EFO_0022148
Disease	total lipids in large VLDL	TDRD15 CETP INTS10	4.60e-03	67	147	3	EFO_0022175
Disease	Microcephaly	LSS DYNC1H1 WDR62	4.60e-03	67	147	3	C0025958
Disease	free cholesterol in large VLDL measurement	TDRD15 CETP INTS10	4.79e-03	68	147	3	EFO_0022265
Disease	aggressive behaviour measurement, ADHD symptom measurement	MFHAS1 MDGA2 HSD3B7	4.79e-03	68	147	3	EFO_0007826, EFO_0007860
Disease	muscular dystrophy (implicated_via_orthology)	FKRP SNTB1	4.86e-03	21	147	2	DOID:9884 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
WKPGSGIIHQIILEN	ACO2	166	Q99798
WHTVDQSPVLILGGI	CATSPERG	241	Q6ZRH7
ALWGEAGAVHEAPLR	ERICH3	796	Q5RHP9
HLAKIGLREENQPGW	ARHGEF10L	751	Q9HCE6
KLLLHLQGEREPGWI	CETP	166	P11597
LAGNEIEHIPVWLGK	CNTRL	176	Q7Z7A1
GRLDWETLVHENLPG	CATSPER2	466	Q96P56
LIAPGQRGILLLWFE	CATSPERD	246	Q86XM0
QGLALLPRVEWSGAI	LINC00269	26	Q8N2A0
HALIEQWNPVGLVGI	ALDH7A1	176	P49419
ERGLVHIWQAGSFPI	ALS2	16	Q96Q42
IPGHDWCVLRLGIQG	ALLC	56	Q8N6M5
WTHIRLNIFPDGGIA	ALLC	161	Q8N6M5
GVHLLGAAVQPALAW	DNM1P46	101	Q6ZS02
LGELRVFDQHLGPWL	HSD3B7	36	Q9H2F3
EAWGLADVRELHPGL	ACAP3	656	Q96P50
ASGIWELHPRVGDLI	GLE1	506	Q53GS7
LLHAQPIISIRVWGV	APBB1	441	O00213
HQPIVEGLRWLLAVI	ARL13A	176	Q5H913
WGDRIPLEILVQIFG	FBXL6	111	Q8N531
QGGAWLLLEKVHQLP	DNHD1	1731	Q96M86
LQVLHAEWDPIAGAL	DNHD1	4656	Q96M86
PLWLAANGGHLDVVQ	ANKRD17	1356	O75179
APVVLHQEFLGRDLW	PDSS2	316	Q86YH6
GVILGVALWLRHDPQ	CD81	26	P60033
LVQHWVPGARLVEEL	ABCA7	1081	Q8IZY2
VQGEIHLRLEVWPGA	RASA4	116	O43374
LQEGHRLWIGNLDPK	RBM18	21	Q96H35
SFVPGIHLDLGWIAI	OCA2	641	Q04671
VQGEIHLRLEVWPGA	RASA4B	116	C9J798
GPRVKLQLWDTAGHE	RAB42	61	Q8N4Z0
TLVGKEGPQWLHVRD	TSPOAP1	246	O95153
GLAVPEEHVWGLLRP	NUDT8	91	Q8WV74
PGALELAWQHRVFVG	ISYNA1	286	Q9NPH2
LGHVIVLLQQEWPRG	INTS10	586	Q9NVR2
HEIEGTGLPQAQLLW	NIBAN2	46	Q96TA1
GNLGLIAVIWKDPHL	OR5H15	41	A6NDH6
VQWLRAHLGIVSQEP	ABCB1	1106	P08183
GWAGLIVVVENRHPK	CAPN15	981	O75808
LVTPLGVGTHLVWDR	OXSM	51	Q9NWU1
GVPEALRGEVWQLLA	RABGAP1	566	Q9Y3P9
VGLTLLRVWDAEHPG	NUP210	1451	Q8TEM1
PRILDLRQHLEGWGH	PHLDB3	506	Q6NSJ2
DLGIPQKAAWRLLHV	FAT1	796	Q14517
GNLGLIAVIWKDPHL	OR5H14	41	A6NHG9
GDIITVLEQHPDGRW	CASKIN1	306	Q8WXD9
ILHLGLPWGNVAVER	KIAA0100	1061	Q14667
RDGPLLAALKAGHWV	MDN1	1806	Q9NU22
IWEVLRKLGLRPGIH	MAGED2	391	Q9UNF1
WIVRRAEGLGHEQTP	MAP6	246	Q96JE9
INLHVRGGYILPWQE	MGAM2	1661	Q2M2H8
VRVTFLGLQHWVPEL	MFGE8	91	Q08431
VLPDHFGQLSRVGLW	MFHAS1	356	Q9Y4C4
VDVWVIEPQGLRFLH	ITIH2	211	P19823
DLEIIPALLHGDLWG	FN3KRP	206	Q9HA64
SLPGVEALVGWLLDH	HERC2	2491	O95714
VLEAQRGYVGLIWPH	DST	1851	Q03001
VARWGGVALPREHIE	FOXD4L4	61	Q8WXT5
VARWGGVALPREHIE	FOXD4L3	61	Q6VB84
NGFLPIHLLGLRVDW	ATP1A1	876	P05023
IALPENICGIGWHLV	ATRN	781	O75882
LPGRQEHVFWKLVLV	MCM3AP	1351	O60318
WLRKHGEEQQLPAVG	ECE2	726	P0DPD6
LRWIGPEKGVVHLAT	ENOSF1	101	Q7L5Y1
IQKGWVLHGVPRDLD	AK8	346	Q96MA6
WGGIKQLLHILQGDR	NEK10	331	Q6ZWH5
LLGRWGPNHAADPII	NUDT9	161	Q9BW91
LRSVQLPDGGWGLHI	LSS	131	P48449
LGVLVHWALLAGPQK	NAXD	281	Q8IW45
RGVPWLFLQQILEEH	EVC2	766	Q86UK5
LRNVWVHLDGPGVTR	F13A1	661	P00488
FQILEIRHGGHWPLG	GPR152	86	Q8TDT2
HIGAAAGIALLAWPV	GDPD2	161	Q9HCC8
VINVSPLEWGHVLLV	GDPGP1	156	Q6ZNW5
WLRDPGGQRLVVLHL	AMH	121	P03971
GGQRLVVLHLEEVTW	AMH	126	P03971
VIRGPFLVALGKSWH	PDLIM5	426	Q96HC4
QVARWGGVALPREHI	FOXD4	56	Q12950
LWVTLTGIEGHRVEP	HK3	106	P52790
LPLHVGLTVRLAVGW	GPR35	231	Q9HC97
DGAVGILVHIWLFPI	MDGA2	931	Q7Z553
ILQLHAGVVPDLLWA	PAQR4	251	Q8N4S7
GNLGLIAVIWKDPHL	OR5H1	41	A6NKK0
AHAGPIWLRGGLVLF	OTOP2	96	Q7RTS6
QALGEPIRQGHFIVW	OBSCN	5891	Q5VST9
LVLVVGLPANGLALW	F2RL3	86	Q96RI0
GHLRPGDEVLEWNGR	RIMS2	711	Q9UQ26
SWPGLGLEDHQEIVL	RGL4	96	Q8IZJ4
EVKLLGHGQPLNWIS	FUCA2	421	Q9BTY2
PGGKEHLVWQILANV	ADCY2	181	Q08462
YDIHVGLRGVPLLEW	CLCN6	576	P51797
DWGNEHLGLDLVPRK	DOCK3	151	Q8IZD9
SLPILAVPIARGGHW	C5AR2	86	Q9P296
EHFWATLIRVPGIPG	GCNT4	336	Q9P109
HALVQERRKFGPLGW	DNAH7	3586	Q8WXX0
QPKEHWIGRGVALLC	DNAH7	4006	Q8WXX0
GLWGHPVLAVRVLFE	DENND4C	831	Q5VZ89
LEGQLILRPSNGIWI	CYP4V2	501	Q6ZWL3
VAELGHLLWKGRPRA	GJD3	206	Q8N144
DHQLLWGEALLITPV	GAA	741	P10253
LSDPVQLEVHIGWLL	FCGR3B	96	O75015
QLEVHIGWLLLQAPR	FCGR3B	101	O75015
LGKHELVPVLGSRWL	MARVELD1	81	Q9BSK0
LGFIPVAWNLHGILR	CLDN2	131	P57739
VARWGGVALPREHIE	FOXD4L1	61	Q9NU39
LPVEGLIRIWAHEAL	DYNC1H1	2816	Q14204
SLLGAARHGDIIPWD	FKRP	346	Q9H9S5
LSDPVQLEVHIGWLL	FCGR3A	96	P08637
QLEVHIGWLLLQAPR	FCGR3A	101	P08637
EKRRHEGLPGLAVQW	FASN	2046	P49327
LVHIDNLRWEGVPFI	H6PD	341	O95479
IDLHFATKGLQGWPR	B9D2	61	Q9BPU9
GLLGNVFLHLLPEAW	SLC39A13	116	Q96H72
LARVQALGWHGPLLA	MFSD13A	96	Q14CX5
PVEVVRLGSAHIWLQ	KIF28P	631	B7ZC32
ADAPIIGHLWEFVLG	CPT1B	476	Q92523
GLGQLKELEIHLWPS	LINGO4	226	Q6UY18
GALHRWALAVPPGAV	OTUD5	76	Q96G74
AGRLGLDWPAVALHL	PIDD1	796	Q9HB75
ILNGIPGLERVHVWI	OR52N5	21	Q8NH56
LGGLQHNTVLVGWPR	SLC12A5	786	Q9H2X9
DDVAALHGPVVRQLW	IL4I1	421	Q96RQ9
ILVGIPGLEQFHVWI	OR52H1	21	Q8NGJ2
LLVGIPGLEESQHWI	OR52L1	31	Q8NGH7
FLVGIPGLEESQHWI	OR52L2P	31	Q8NGH6
LNGIPGLEDVHLWIS	OR52N1	16	Q8NH53
REIRHLGWLAEKVPG	SNTB1	321	Q13884
NHWELKGVPIRLEVG	EPRS1	1356	P07814
CPLLQGHWGGEVLIV	SLC52A3	386	Q9NQ40
NLPTIHWGNEEIGLL	TBC1D22B	471	Q9NU19
VPQLGIHAFLSGVKW	TDRD15	1401	B5MCY1
LAGVPLIGWVLRAAL	CMAS	66	Q8NFW8
NTIGPHWDLFVIGLI	SEL1L2	661	Q5TEA6
PRELWHEINGLLVGF	NTHL1	271	P78549
GGAIINPVWILTAAH	OVCH1	601	Q7RTY7
VARWGGVALPREHIE	FOXD4L5	61	Q5VV16
VARWGGVALPREHIE	FOXD4L6	61	Q3SYB3
GLRNLLANVDGWPIL	SLC2A5	181	P22732
GLEIVPALLHGDLWS	FN3K	206	Q9H479
HRLKPWLVGLAAVVG	SMIM24	26	O75264
LLINRDLVGPLAWHP	SIRT3	341	Q9NTG7
AVSLGPWVHLIEELQ	SEMA4C	451	Q9C0C4
PVQKQGLWLDVHALG	AARS2	486	Q5JTZ9
LVRLQWDLGLGHLPR	RRP12	401	Q5JTH9
GQELAHWIIHGRPEK	SARDH	421	Q9UL12
RLSFVGELGWELHIP	SARDH	726	Q9UL12
LVNPLRHGIIVDWDT	ACTL7A	131	Q9Y615
GPILLIVGQDDHNWR	ACOT4	316	Q8N9L9
RLLNKHVIWGGEPRA	ACOT4	376	Q8N9L9
GEVWGPLIRHRALAA	CHRD	266	Q9H2X0
PHIRRAIQGGLEWLK	CLCNKA	26	P51800
RSLVWGPGLQAAVVL	POGLUT3	31	Q7Z4H8
PLVHEVRGTWFLAGL	PRSS53	481	Q2L4Q9
VLLRQGHGPEADVWS	PLK3	231	Q9H4B4
HLISQLERGEGPWVA	ZFP92	61	A6NM28
PAQRLVGWIDHILQT	UGT3A1	451	Q6NUS8
VVTVGLDGATRLWHP	TEP1	2211	Q99973
INNWLLIEGHTIGIG	POLR2A	676	P24928
GPGRWVVLAAVLIGL	ST14	51	Q9Y5Y6
LSGLQKVHWGLRPDQ	SLC4A5	51	Q9BY07
HIRRPWGIAVGLLCQ	SLC10A6	61	Q3KNW5
QRNLPWKFEHIGIGL	PSME4	1156	Q14997
RPGAVDVVRHWQDLG	PITPNM3	761	Q9BZ71
IVTGENGHRPAVRIW	WDR62	126	O43379
KIGLIHGHQVIPWGD	VPS29	81	Q9UBQ0
LNRSPEHGVWLIGLK	TRIM50	376	Q86XT4
PGRVLFIDNWRVLHG	TMLHE	376	Q9NVH6
LRVPEEGQGHWLVVQ	XRRA1	26	Q6P2D8
QRLPAGWTRVEVHGL	WDR81	96	Q562E7
LRGWPAHEGDILQIK	WDR81	1821	Q562E7
GGDDKVIRLWHPNIS	WDR64	341	B1ANS9
LNGHRVALPVWLAQG	ZAN	1621	Q9Y493
VLLPVWEAEGLGLRV	HECTD3	61	Q5T447
WAGRPQDGVAVLVRH	MYO1C	686	O00159
LRGIGWIPLDSVDHV	NEB	4361	P20929