Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DYNC1H1 DNAH14

7.59e-0518933GO:0008569
GeneOntologyCellularComponentlateral element

SYCP2 BRCA1 BRCA2 SYCP1

1.41e-0619944GO:0000800
GeneOntologyCellularComponentsynaptonemal complex

SYCP2 BRCA1 BRCA2 SYCP1

5.41e-0546944GO:0000795
GeneOntologyCellularComponentsynaptonemal structure

SYCP2 BRCA1 BRCA2 SYCP1

5.41e-0546944GO:0099086
GeneOntologyCellularComponentdynein complex

DNAI1 DYNC2H1 DYNC1H1 DNAH14

1.02e-0454944GO:0030286
GeneOntologyCellularComponentcytoplasmic region

DNAI1 DYNC2H1 PCLO CFAP206 DLG2 RP1 SPAG8 DYNC1H1

2.20e-04360948GO:0099568
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAI1 DYNC2H1 CFAP206 DLG2 RP1 SPAG8 DYNC1H1

5.72e-04317947GO:0032838
GeneOntologyCellularComponentcondensed nuclear chromosome

SYCP2 BRCA1 BRCA2 SYCP1

7.60e-0491944GO:0000794
GeneOntologyCellularComponentmicrotubule associated complex

DNAI1 DYNC2H1 RP1 DYNC1H1 DNAH14

8.05e-04161945GO:0005875
GeneOntologyCellularComponentnuclear ubiquitin ligase complex

FZR1 BRCA1 BRCA2

1.40e-0349943GO:0000152
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DYNC1H1 DNAH14

4.32e-0514943IPR024317
DomainDynein_HC_stalk

DYNC2H1 DYNC1H1 DNAH14

4.32e-0514943IPR024743
DomainMT

DYNC2H1 DYNC1H1 DNAH14

4.32e-0514943PF12777
DomainAAA_8

DYNC2H1 DYNC1H1 DNAH14

4.32e-0514943PF12780
DomainDHC_fam

DYNC2H1 DYNC1H1 DNAH14

5.38e-0515943IPR026983
DomainDynein_heavy_dom

DYNC2H1 DYNC1H1 DNAH14

5.38e-0515943IPR004273
DomainDynein_heavy

DYNC2H1 DYNC1H1 DNAH14

5.38e-0515943PF03028
DomainSYCP1/2

SYCP2 SYCP1

7.49e-053942IPR024835
DomainSH3_9

CASS4 ARHGAP32 SH3D19 NEB

6.46e-0478944PF14604
DomainDHC_N1

DYNC2H1 DYNC1H1

6.88e-048942PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DYNC1H1

6.88e-048942IPR013594
DomainSH3

CASS4 ARHGAP32 MIA3 SH3D19 DLG2 NEB

7.80e-04216946SM00326
DomainSH3

CASS4 ARHGAP32 MIA3 SH3D19 DLG2 NEB

7.80e-04216946PS50002
DomainSH3_domain

CASS4 ARHGAP32 MIA3 SH3D19 DLG2 NEB

8.58e-04220946IPR001452
DomainChromo_dom_subgr

CDY2A CDY1

1.10e-0310942IPR017984
DomainSH3_1

CASS4 ARHGAP32 SH3D19 DLG2 NEB

1.44e-03164945PF00018
DomainDynein_heavy_dom-2

DYNC2H1 DYNC1H1

2.19e-0314942IPR013602
DomainDHC_N2

DYNC2H1 DYNC1H1

2.19e-0314942PF08393
DomainATPase_dyneun-rel_AAA

DYNC2H1 DYNC1H1

2.19e-0314942IPR011704
DomainAAA_5

DYNC2H1 DYNC1H1

2.19e-0314942PF07728
DomainCrotonase_core_superfam

CDY2A CDY1

3.24e-0317942IPR001753
DomainECH_1

CDY2A CDY1

3.24e-0317942PF00378
DomainG_patch

AGGF1 NKRF

5.92e-0323942SM00443
DomainG_patch_dom

AGGF1 NKRF

5.92e-0323942IPR000467
DomainG_PATCH

AGGF1 NKRF

5.92e-0323942PS50174
DomainG-patch

AGGF1 NKRF

5.92e-0323942PF01585
Pubmed

BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes.

SYCP2 BRCA1 SYCP1

1.64e-06995319531582
Pubmed

Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.

SYCP2 BRCA1 BRCA2 SYCP1

1.77e-063295427739607
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ABCC1 ARHGAP32 TRMT10C MIA3 PPP2R5D MOSPD2 PTPRC KCNMA1 TAB2 PTPN22 MPHOSPH9 GPRIN1 LUZP1

5.63e-061049951327880917
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ARHGAP32 CNOT11 MIA3 NRBF2 ICE2 TAB2 MPHOSPH9

6.04e-0625195729778605
Pubmed

Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis.

SYCP2 BRCA1 SYCP1

7.03e-061495322346761
Pubmed

Association of BRCA1/2 mutations with ovarian cancer prognosis: An updated meta-analysis.

BRCA1 BRCA2

7.38e-06295229480828
Pubmed

A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.

BRCA1 BRCA2

7.38e-06295217924331
Pubmed

Attitudes, knowledge, risk perceptions and decision-making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses.

BRCA1 BRCA2

7.38e-06295212833555
Pubmed

Randomised trial of a decision aid and its timing for women being tested for a BRCA1/2 mutation.

BRCA1 BRCA2

7.38e-06295214735173
Pubmed

Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

7.38e-06295216032702
Pubmed

Oral contraceptive use and BRCA penetrance: a case-only study.

BRCA1 BRCA2

7.38e-06295219549808
Pubmed

Prevalence of BRCA1 and BRCA2 Mutations Among Patients With Ovarian, Primary Peritoneal, and Fallopian Tube Cancer in India: A Multicenter Cross-Sectional Study.

BRCA1 BRCA2

7.38e-06295234101484
Pubmed

Olaparib monotherapy in patients with advanced relapsed ovarian cancer and a germline BRCA1/2 mutation: a multistudy analysis of response rates and safety.

BRCA1 BRCA2

7.38e-06295226961146
Pubmed

Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of PENN II model to previous study.

BRCA1 BRCA2

7.38e-06295220512419
Pubmed

Deleterious and ethnic-related BRCA1/2 mutations in tissue and blood of Egyptian colorectal cancer patients and its correlation with human papillomavirus.

BRCA1 BRCA2

7.38e-06295237804357
Pubmed

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

BRCA1 BRCA2

7.38e-06295222053997
Pubmed

BRCA mutations in women with inflammatory breast cancer.

BRCA1 BRCA2

7.38e-06295229044548
Pubmed

Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy.

BRCA1 BRCA2

7.38e-06295233834176
Pubmed

Should genetic testing for BRCA1/2 be permitted for minors? Opinions of BRCA mutation carriers and their adult offspring.

BRCA1 BRCA2

7.38e-06295218200524
Pubmed

Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.

BRCA1 BRCA2

7.38e-06295229298688
Pubmed

Fertility in women with BRCA mutations: a case-control study.

BRCA1 BRCA2

7.38e-06295219200971
Pubmed

Prevalence of BRCA mutations and founder effect in high-risk Hispanic families.

BRCA1 BRCA2

7.38e-06295216030099
Pubmed

Prevalence of BRCA1 and BRCA2 large genomic rearrangements in Tunisian high risk breast/ovarian cancer families: Implications for genetic testing.

BRCA1 BRCA2

7.38e-06295228212807
Pubmed

Genetic counseling impacts decision for prophylactic surgery for patients perceived to be at high risk for breast cancer.

BRCA1 BRCA2

7.38e-06295211448436
Pubmed

Rapid evolution of BRCA1 and BRCA2 in humans and other primates.

BRCA1 BRCA2

7.38e-06295225011685
Pubmed

Breast magnetic resonance imaging for screening high-risk women.

BRCA1 BRCA2

7.38e-06295223928241
Pubmed

Heterozygous BRCA1 and BRCA2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer.

BRCA1 BRCA2

7.38e-06295235980168
Pubmed

Tubal ligation and risk of ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.

BRCA1 BRCA2

7.38e-06295211377596
Pubmed

BRCA mutations and risk of prostate cancer in Ashkenazi Jews.

BRCA1 BRCA2

7.38e-06295215131025
Pubmed

Broad BRCA1 and BRCA2 mutational spectrum and high incidence of recurrent and novel mutations in the eastern Spain population.

BRCA1 BRCA2

7.38e-06295220033483
Pubmed

Health survey and assessment of the polymorphisms BRCA1/P871L, BRCA1/Q356R, and BRCA2/N372H in female gas station workers in Rio de Janeiro.

BRCA1 BRCA2

7.38e-06295228862356
Pubmed

BRCA1 and BRCA2 germline mutations in Moroccan breast/ovarian cancer families: novel mutations and unclassified variants.

BRCA1 BRCA2

7.38e-06295222425665
Pubmed

BRCA1/2 in high-risk African American women with breast cancer: providing genetic testing through various recruitment strategies.

BRCA1 BRCA2

7.38e-06295218752448
Pubmed

Peritoneal washing cytology in patients with BRCA1 or BRCA2 mutations undergoing risk-reducing salpingo-oophorectomies: a 10-year experience and reappraisal of its clinical utility.

BRCA1 BRCA2

7.38e-06295222425664
Pubmed

Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.

BRCA1 BRCA2

7.38e-06295222970155
Pubmed

Anti-müllerian hormone levels and antral follicle count in women with a BRCA1 or BRCA2 germline pathogenic variant: A retrospective cohort study.

BRCA1 BRCA2

7.38e-06295234304065
Pubmed

Absence of 185delAG and 6174delT Mutations among Breast Cancer Patients of Eastern India.

BRCA1 BRCA2

7.38e-06295226625823
Pubmed

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.

BRCA1 BRCA2

7.38e-06295226852015
Pubmed

Meta-analysis of BRCA1 and BRCA2 penetrance.

BRCA1 BRCA2

7.38e-06295217416853
Pubmed

Power spectral analysis of mammographic parenchymal patterns for breast cancer risk assessment.

BRCA1 BRCA2

7.38e-06295218175183
Pubmed

Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients.

BRCA1 BRCA2

7.38e-06295238057686
Pubmed

Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil.

BRCA1 BRCA2

7.38e-06295227914478
Pubmed

BRCA1 and BRCA2 germline mutations in Korean breast cancer patients at high risk of carrying mutations.

BRCA1 BRCA2

7.38e-06295216455195
Pubmed

The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial.

BRCA1 BRCA2

7.38e-06295223810788
Pubmed

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.

BRCA1 BRCA2

7.38e-06295229727326
Pubmed

Risk reducing surgery with peritoneal staging in BRCA1-2 mutation carriers. A prospective study.

BRCA1 BRCA2

7.38e-06295235871032
Pubmed

Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry.

BRCA1 BRCA2

7.38e-06295222739995
Pubmed

The impact of a panel of 18 SNPs on breast cancer risk in women attending a UK familial screening clinic: a case-control study.

BRCA1 BRCA2

7.38e-06295227794048
Pubmed

Breast cancer surgery trend changes since the introduction of BRCA1/2 mutation screening: a retrospective cohort analysis of 158 mutation carriers treated at a single institution.

BRCA1 BRCA2

7.38e-06295220972632
Pubmed

BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients.

BRCA1 BRCA2

7.38e-06295219499246
Pubmed

Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation.

BRCA1 BRCA2

7.38e-06295219656164
Pubmed

Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.

BRCA1 BRCA2

7.38e-06295215986445
Pubmed

Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer.

BRCA1 BRCA2

7.38e-06295218165636
Pubmed

Large genomic rearrangements in BRCA1 and BRCA2: implications for patient care.

BRCA1 BRCA2

7.38e-06295223615136
Pubmed

Clinicopathologic features and BRCA mutations in primary fallopian tube cancer in Japanese women.

BRCA1 BRCA2

7.38e-06295229982601
Pubmed

Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

7.38e-06295228343309
Pubmed

BRCA1 and BRCA2 genetic testing in Hispanic patients: mutation prevalence and evaluation of the BRCAPRO risk assessment model.

BRCA1 BRCA2

7.38e-06295217925560
Pubmed

Intratumor Heterogeneity of Homologous Recombination Deficiency in Primary Breast Cancer.

BRCA1 BRCA2

7.38e-06295227601588
Pubmed

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

7.38e-06295223918944
Pubmed

Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms.

BRCA1 BRCA2

7.38e-06295233558422
Pubmed

Breast cancer risk associated with BRCA1/2 variants in the Pakistani population.

BRCA1 BRCA2

7.38e-06295230430339
Pubmed

Satisfaction with prophylactic risk-reducing salpingo-oophorectomy in BRCA mutation carriers is very high and little dependent on the participants' characteristics at surgery: a prospective study.

BRCA1 BRCA2

7.38e-06295233534430
Pubmed

BRCA 1, 2 mutation and earlier menopause: could BRCA 1,2 be used as predictor of menopause?

BRCA1 BRCA2

7.38e-06295234137566
Pubmed

BRCA1/2 Mutation Detection in the Tumor Tissue from Selected Polish Patients with Breast Cancer Using Next Generation Sequencing.

BRCA1 BRCA2

7.38e-06295233918338
Pubmed

Effect of Oophorectomy on Survival After Breast Cancer in BRCA1 and BRCA2 Mutation Carriers.

BRCA1 BRCA2

7.38e-06295226181175
Pubmed

Mutational analysis of BRCA1 and BRCA2 in Mediterranean Spanish women with early-onset breast cancer: identification of three novel pathogenic mutations.

BRCA1 BRCA2

7.38e-06295214517958
Pubmed

Better life expectancy in women with BRCA2 compared with BRCA1 mutations is attributable to lower frequency and later onset of ovarian cancer.

BRCA1 BRCA2

7.38e-06295218559571
Pubmed

BRCA1-2 diagnostic workflow from next-generation sequencing technologies to variant identification and final report.

BRCA1 BRCA2

7.38e-06295227225819
Pubmed

BRCA1 and BRCA2 mutation prevalence and clinical characteristics of a population-based series of ovarian cancer cases from Denmark.

BRCA1 BRCA2

7.38e-06295218559594
Pubmed

Characterization of BRCA1 and BRCA2 genetic variants in a cohort of Bahraini breast cancer patients using next-generation sequencing.

BRCA1 BRCA2

7.38e-06295231131559
Pubmed

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

BRCA1 BRCA2

7.38e-06295211981002
Pubmed

Identification of twenty-nine novel germline unclassified variants of BRCA1 and BRCA2 genes in 1400 Italian individuals.

BRCA1 BRCA2

7.38e-06295229020660
Pubmed

An emerging entity: pancreatic adenocarcinoma associated with a known BRCA mutation: clinical descriptors, treatment implications, and future directions.

BRCA1 BRCA2

7.38e-06295221934105
Pubmed

Revertant mosaicism for family mutations is not observed in BRCA1/2 phenocopies.

BRCA1 BRCA2

7.38e-06295228199346
Pubmed

Results of a population-based screening for hereditary breast cancer in a region of North-Central Italy: contribution of BRCA1/2 germ-line mutations.

BRCA1 BRCA2

7.38e-06295218092194
Pubmed

Diet, lifestyle and BRCA-related breast cancer risk among French-Canadians.

BRCA1 BRCA2

7.38e-06295216541324
Pubmed

Investigating the relationship between BRCA1 and BRCA2 genes methylation profile and sperm DNA fragmentation in infertile men.

BRCA1 BRCA2

7.38e-06295231095775
Pubmed

Ethnic-specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population.

BRCA1 BRCA2

7.38e-06295236385461
Pubmed

Screening for Genetic Testing in Breast Cancer - Are We Missing the Full Picture?

BRCA1 BRCA2

7.38e-06295226254840
Pubmed

Contribution of BRCA1 germ-line mutations to breast cancer in Greece: a hospital-based study of 987 unselected breast cancer cases.

BRCA1 BRCA2

7.38e-06295219491894
Pubmed

Young age at first pregnancy does protect against early onset breast cancer in BRCA1 and BRCA2 mutation carriers.

BRCA1 BRCA2

7.38e-06295229116468
Pubmed

BRCA1 and BRCA2 mutations in males with familial breast and ovarian cancer syndrome. Results of a Spanish multicenter study.

BRCA1 BRCA2

7.38e-06295226026974
Pubmed

Etiology of familial breast cancer with undetected BRCA1 and BRCA2 mutations: clinical implications.

BRCA1 BRCA2

7.38e-06295224306927
Pubmed

[Germline mutations in the BRCA1 and BRCA2 genes from breast cancer families in China Han people].

BRCA1 BRCA2

7.38e-06295215059511
Pubmed

The impact of reproductive life on breast cancer risk in women with family history or BRCA mutation.

BRCA1 BRCA2

7.38e-06295227880720
Pubmed

BRCA1 and BRCA2 mutations in Turkish familial and non-familial ovarian cancer patients: a high incidence of mutations in non-familial cases.

BRCA1 BRCA2

7.38e-06295212112655
Pubmed

Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?

BRCA1 BRCA2

7.38e-06295222339411
Pubmed

Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants.

BRCA1 BRCA2

7.38e-06295234906479
Pubmed

Validation of Version 3.0 of the Breast Cancer Genetics Referral Screening Tool (B-RST™).

BRCA1 BRCA2

7.38e-06295229740170
Pubmed

Elevated expression of Ki-67 identifies aggressive prostate cancers but does not distinguish BRCA1 or BRCA2 mutation carriers.

BRCA1 BRCA2

7.38e-06295220043088
Pubmed

Utilization of breast cancer screening in a clinically based sample of women after BRCA1/2 testing.

BRCA1 BRCA2

7.38e-06295212376518
Pubmed

Characterization and in silico analyses of the BRCA1/2 variants identified in individuals with personal and/or family history of BRCA-related cancers.

BRCA1 BRCA2

7.38e-06295232599251
Pubmed

Oral contraceptive use and breast or ovarian cancer risk in BRCA1/2 carriers: a meta-analysis.

BRCA1 BRCA2

7.38e-06295220537530
Pubmed

Multiple founder effects and geographical clustering of BRCA1 and BRCA2 families in Finland.

BRCA1 BRCA2

7.38e-06295211039575
Pubmed

Germline and Somatic BRCA1/2 Gene Mutational Status and Clinical Outcomes in Epithelial Peritoneal, Ovarian, and Fallopian Tube Cancer: Over a Decade of Experience in a Single Institution in Korea.

BRCA1 BRCA2

7.38e-06295232718143
Pubmed

Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis.

BRCA1 BRCA2

7.38e-06295220309627
Pubmed

BRCA mutational status, initial disease presentation, and clinical outcome in high-grade serous advanced ovarian cancer: a multicenter study.

BRCA1 BRCA2

7.38e-06295228549976
Pubmed

Next Generation Sequencing Reveals High Prevalence of BRCA1 and BRCA2 Variants of Unknown Significance in Early-Onset Breast Cancer in African American Women.

BRCA1 BRCA2

7.38e-06295228439188
Pubmed

BRCA1/2 test results impact risk management attitudes, intentions, and uptake.

BRCA1 BRCA2

7.38e-06295220383578
Pubmed

Assessment of ovarian reserve and reproductive outcomes in BRCA1 or BRCA2 mutation carriers.

BRCA1 BRCA2

7.38e-06295231780568
InteractionYWHAZ interactions

BDP1 FNDC3B ARHGAP32 FZR1 BRCA1 DCP1B DOCK9 SH3D19 KCNMA1 ANKRD34A PAK2 TAB2 WDR5 MPHOSPH9 NEB SQOR DYNC1H1 LUZP1 GAB2

9.03e-0613199419int:YWHAZ
InteractionYWHAB interactions

ARHGAP32 PPP2R5D DCP1B RPS6KA1 DOCK9 SH3D19 DENND2C KCNMA1 ANKRD34A PAK2 MPHOSPH9 NEB DYNC1H1 LUZP1 GAB2 SRSF12

1.70e-0510149416int:YWHAB
InteractionZYX interactions

CASS4 ARHGAP32 DCP1B SH3D19 HIPK2 TAB2 MPHOSPH9 RGS2 LUZP1

2.32e-05329949int:ZYX
GeneFamilyDyneins, cytoplasmic

DYNC2H1 DYNC1H1

9.09e-0413632538
GeneFamilyDyneins, axonemal

DNAI1 DNAH14

1.57e-0317632536
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

BRCA1 BRCA2

2.18e-0320632548
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

AGGF1 NKRF

2.64e-0322632579
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

BDP1 ARHGAP32 BRCA1 BRCA2 ICE2 HIPK2 CKAP2L MPHOSPH9 LUZP1

5.30e-06291939Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4

BDP1 BRCA1 BRCA2 ICE2 PCLO MPHOSPH9 LUZP1

2.18e-05192937Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

BDP1 BRCA1 BRCA2 ICE2 CKAP2L MPHOSPH9 NKRF LUZP1

6.70e-05311938Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5

BDP1 DNAI1 BRCA2 ICE2 CKAP2L MPHOSPH9 LUZP1 SRSF12

1.03e-04331938Facebase_RNAseq_e10.5_Mandibular Arch_1000_K5
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

CCDC117 SYCP2 BRCA2 ICE2 SYCP1

1.23e-04110935gudmap_dev gonad_e13.5_M_GermCell_Oct_k4_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

BDP1 BRCA2 ICE2 CKAP2L MPHOSPH9 LUZP1

1.69e-04186936Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_100

SYCP2 SYCP1

1.88e-045932gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k1_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

BDP1 BRCA1 BRCA2 DYNC2H1 MPHOSPH9 LUZP1

2.01e-04192936Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM SYCP2 XIRP2 PIK3C2G PCLO GRIN2B NEB

1.39e-071849572cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM SYCP2 XIRP2 PIK3C2G PCLO GRIN2B NEB

1.39e-07184957ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM SYCP2 XIRP2 PIK3C2G PCLO GRIN2B NEB

1.39e-071849572b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PCLO PEG3 ANKRD34A DISP2 GRIN2B GPRIN1 SRSF12

1.50e-071869573f889083fcffe516388e9b03a5e23af2010ced33
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CASS4 MGAM LPO GRIN2B PLEKHH2 SQOR

6.13e-07142956191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CASS4 MGAM LPO GRIN2B PLEKHH2 SQOR

6.39e-07143956b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CASS4 ABCC1 XIRP2 DLG2 GRIN2B HS3ST4

2.36e-0617995614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PIK3C2G DOCK9 SLC19A3 LAMA3 DLG2 DNAH14

3.44e-0619195634cc997e4e5c727495f321e6807a84aa124da486
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PIK3C2G DOCK9 SLC19A3 LAMA3 DLG2 DNAH14

3.54e-06192956fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CASS4 MGAM NRBF2 TREM1 RGS2 GAB2

3.76e-06194956ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B CFAP206 RP1 SPAG8

3.76e-06194956a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCellmild-Myeloid-Neutrophils_3|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CASS4 MGAM NRBF2 TREM1 RGS2 GAB2

3.87e-06195956a1cfed0092debcc003eff6a62508556b7664d5e1
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Neuronal-CPNs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

DOCK9 PCLO DLG2 DISP2 GRIN2B GPRIN1

3.99e-06196956c9e7ac34993c873de4f198cdae77dcf099731532
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CASS4 SH3D19 DLG2 LSAMP PLEKHH2 DNAH14

4.11e-06197956f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

BDP1 DOCK9 PCLO DLG2 LSAMP GRIN2B

4.48e-06200956db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

BDP1 DOCK9 PCLO DLG2 LSAMP GRIN2B

4.48e-0620095630a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellControl-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

CASS4 LPO GRIN2B PLEKHH2 SQOR

1.17e-05138955b7920c9a28d28220e7e4b30cd91ba13d0548eb76
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MGAM SYCP2 PTPRC TREM1 IL1RL1

1.64e-0514895574f1f9d1a53dc1a09cb6a504cbbdc7496c5b6879
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 MGAM SYCP2 PTPRC TREM1

2.18e-05157955320d5ac063fd90e26f537475c328b3ae73974bc1
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 MGAM SYCP2 PTPRC TREM1

2.18e-05157955e4b17c267b754c5af95cdf17f629354d1a8a8ad7
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2G SYCP1 KCNMA1 GRIN2B PLEKHH2

2.39e-05160955c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2G SYCP1 KCNMA1 GRIN2B PLEKHH2

2.39e-0516095525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MGAM SYCP2 PTPRC TREM1 RGS2

2.54e-05162955ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MGAM SYCP2 PTPRC TREM1 RGS2

2.54e-051629554e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-Activated_CD8_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAI1 PTPRC PTPN22 MPHOSPH9 SPAG8

2.69e-0516495524fdea5113d92b96f56b06dd2449910a3c785e69
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DNAI1 DYNC2H1 CFAP206 RP1 SPAG8

2.94e-0516795526cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SH3D19 LAMA3 DLG2 LSAMP PLEKHH2

3.87e-05177955b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellsevere-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CASS4 PTPRC TREM1 RGS2 GAB2

3.87e-05177955d1ad35ee3d2a84b1d01126d0a38464ab858c00d0
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2G DENND2C PEG3 GPRIN1 CHRNA5

3.87e-051779559b02fd91c110b405eba6cb74ceb90b1286535973
ToppCellLPS-antiTNF-Myeloid-Neutrophils-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FNDC3B MGAM PTPRC TREM1 GAB2

3.98e-05178955afcc92e8fe313c85eaf617cf4dbc3058da6c99d6
ToppCellLPS-antiTNF-Myeloid-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FNDC3B MGAM PTPRC TREM1 GAB2

3.98e-05178955bd689205bc92cda5f71df64c2332ff76adcd84b4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 BRCA2 LAMA3 CKAP2L CHRNA5

4.09e-0517995588d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellLPS-IL1RA-Myeloid-Neutrophils-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FNDC3B MGAM PTPRC TREM1 GAB2

4.20e-05180955c0c07937839652e01df10cc1e70aa005800ea6f6
ToppCellLPS-IL1RA-Myeloid-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FNDC3B MGAM PTPRC TREM1 GAB2

4.20e-05180955079c199425dd3c220f03c6dca1823946f07580a1
ToppCellsevere-Myeloid-Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CASS4 PTPRC TREM1 RGS2 GAB2

4.54e-0518395560a6112aa4fc4f5debda4c7e81b37539ba2e4e6e
ToppCellmild-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CASS4 PTPRC TREM1 RGS2 GAB2

4.66e-051849551a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DYNC2H1 CFAP206 RP1 SPAG8

4.78e-051859555e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAI1 DYNC2H1 FAM229B CFAP206 RP1

4.78e-05185955f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DYNC2H1 CFAP206 RP1 SPAG8

4.91e-0518695576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell18-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

DNAI1 TREM1 CFAP206 RP1 SPAG8

5.03e-051879558d7fa6b2950898e7f283401808378ba2a41b9651
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SH3D19 TRIM55 KCNMA1 LAMA3 RP1

5.03e-0518795587b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SH3D19 TRIM55 KCNMA1 LAMA3 RP1

5.03e-0518795542a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SH3D19 TRIM55 KCNMA1 LAMA3 RP1

5.03e-0518795564afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

DNAI1 DYNC2H1 FAM229B CFAP206 SPAG8

5.16e-051889556833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.16e-05188955803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.16e-051889555ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.29e-0518995557ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.29e-05189955ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 MYPN TRIM55 OSBP2 RP1

5.29e-05189955e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 MYPN TRIM55 OSBP2 RP1

5.29e-05189955b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCellmild-Others|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FSTL1 TREM1 OSBP2 RGS2 GAB2

5.43e-05190955782dc1b612ac1faad7cc2781bfda92a079830d38
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.43e-05190955169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.43e-051909550cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

MGAM PTPRC KCNMA1 RGS2 GAB2

5.43e-05190955d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSTL1 XIRP2 SH3D19 PEG3 LSAMP

5.43e-0519095596a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCellmild-Others-Megakaryocytes|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FSTL1 TREM1 OSBP2 RGS2 GAB2

5.56e-051919550b36223bd7f5758cc37194da6cc252f613bc3c97
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Ddit4l_(Neurofilament,_Layer4?)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

XIRP2 TRIM55 CFAP206

5.68e-0535953afb8cd52dffd630ffe8e7812874d5fd52e0b6752
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

CASS4 ABCC1 PTPRC PTPN22 LUZP1

5.70e-05192955253cf4d2cf88ad8c45b73779336180840bef054b
ToppCellmulticiliated|World / shred by cell class for turbinate

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.70e-051929550f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.70e-05192955d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

5.84e-05193955aa3acc7571405169efb656d214f3a8cbf988362e
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIA1 PCLO PEG3 DISP2 NEB

5.84e-05193955471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCellCOPD-Myeloid|COPD / Disease state, Lineage and Cell class

FNDC3B TREM1 KCNMA1 LSAMP GAB2

5.84e-05193955f58552e286aa27e592497ad78776f58f8ee09841
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ANKRD34A DISP2 SLITRK3 GRIN2B GPRIN1

5.84e-05193955b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CASS4 ABCC1 PTPRC PTPN22 LUZP1

5.84e-051939559c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

PCLO ANKRD34A DLG2 DISP2 GRIN2B

5.99e-051949558aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DYNC2H1 CFAP206 RP1 SPAG8

5.99e-051949551ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.14e-05195955d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.14e-051959550e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.14e-05195955581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.14e-0519595593b1559382a12cfb158aa5fac7386e38b4f87989
ToppCellCF-Myeloid|CF / Disease state, Lineage and Cell class

FNDC3B PTPRC TREM1 RGS2 GAB2

6.14e-05195955ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA3 DYNC2H1 PCLO PEG3 DYNC1H1

6.14e-051959553e519cffa6144a62b06124642a14c9ff39b76554
ToppCellMacrophages-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

PTPRC SLC19A3 TREM1 LSAMP PTPN22

6.14e-051959552af46e87947c16a7c2c367637e606cfbb8a78528
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B CFAP206 SPAG8

6.14e-05195955e22ca35bea06aa95ff2cc771632969f5e7229ffc
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

FNDC3B TREM1 KCNMA1 HIPK2 GAB2

6.14e-0519595546ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.14e-0519595507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.14e-05195955e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA3 DYNC2H1 PCLO PEG3 DYNC1H1

6.14e-051959557796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B CFAP206 SPAG8

6.29e-05196955a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.29e-05196955de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B CFAP206 SPAG8

6.29e-05196955a156840330630e518bc85633dded6f2c3ead3b30
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B CFAP206 SPAG8

6.29e-05196955009e83c7251cf300be78b263634d233a8d972a68
ToppCellBL-critical-LOC-Myeloid-Neutrophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FNDC3B MGAM PTPRC TREM1 RGS2

6.29e-05196955f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCellmild-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CASS4 MGAM NRBF2 TREM1 RGS2

6.29e-051969559c351306b6aae68ed47d4cb1911957bf67f9e1ae
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DYNC2H1 FAM229B CFAP206 SPAG8

6.29e-0519695589ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.29e-05196955d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

DOCK9 PCLO KCNMA1 GRIN2B HS3ST4

6.44e-0519795579b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DYNC2H1 FAM229B RP1 SPAG8

6.44e-0519795571fea4aa6ce96c7693fa94792d08770622873850
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

DOCK9 PCLO KCNMA1 GRIN2B HS3ST4

6.44e-05197955d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

FSTL1 SH3D19 DLG2 LSAMP PLEKHH2

6.44e-05197955fb847f2277609c31fffcdf49517243ce0684facf
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRC SLC19A3 TREM1 KCNMA1 LSAMP

6.60e-05198955e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRC SLC19A3 TREM1 KCNMA1 LSAMP

6.60e-051989550baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP32 PCLO PEG3 KCNMA1 GRIN2B

6.60e-051989558ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

BDP1 PCLO DLG2 LSAMP GRIN2B

6.75e-05199955f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCellmild-Neutrophil|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MGAM SYCP2 TREM1 IL1RL1 RGS2

6.75e-051999552fd5759acf49c02c5bbcc2941676216e7444d76d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

BDP1 PCLO DLG2 LSAMP GRIN2B

6.75e-05199955e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCellmild-Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MGAM SYCP2 TREM1 IL1RL1 RGS2

6.75e-05199955ca319976a7d2576186d0a98cdc93e4c2d5fe8a05
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PCLO PEG3 DISP2 GRIN2B GPRIN1

6.75e-05199955f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellControl-Control-Myeloid-Neutrophil|Control / Disease, condition lineage and cell class

MGAM LPO TREM1 RGS2 GAB2

6.92e-0520095595c41f147a1594d49e73cb56d86d301c3115ce20
Diseaseductal carcinoma in situ (biomarker_via_orthology)

BRCA1 BRCA2

9.20e-062902DOID:0060074 (biomarker_via_orthology)
DiseaseHereditary site-specific ovarian cancer syndrome

BRCA1 BRCA2

9.20e-062902C4749652
DiseaseHereditary breast ovarian cancer syndrome

BRCA1 BRCA2

5.50e-054902cv:C0677776
Diseasehereditary breast ovarian cancer syndrome (is_implicated_in)

BRCA1 BRCA2

9.15e-055902DOID:5683 (is_implicated_in)
Diseasesmall cell lung carcinoma

BRCA2 DYNC2H1 PIWIL4 CHRNA5

1.07e-0480904EFO_0000702
DiseaseAdult only

BRCA1 BRCA2

1.37e-046902C3842001
DiseaseNemaline Myopathy, Childhood Onset

MYPN NEB

1.91e-047902C0546125
Diseasegrapefruit juice consumption measurement

DCP1B PCLO

1.91e-047902EFO_0010094
Diseaseductal carcinoma in situ (is_implicated_in)

BRCA2 PAK2

1.91e-047902DOID:0060074 (is_implicated_in)
Diseaseparasitemia measurement

MYPN LSAMP HS3ST4

1.98e-0437903EFO_0005528
DiseaseBell's palsy

FNDC3B MGAM KCNMA1 LUZP1

2.74e-04102904EFO_0007167
Diseaseresponse to methylphenidate

LSAMP SQOR

3.27e-049902GO_0036271
DiseasePancreatic carcinoma, familial

BRCA1 BRCA2

3.27e-049902C2931038
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

BRCA1 BRCA2 CHRNA5

3.55e-0445903DOID:3748 (is_implicated_in)
DiseaseSchizophrenia

ARHGAP32 FSTL1 BRCA1 TREM1 PAK2 DLG2 LSAMP GRIN2B RGS2 CHRNA5

3.61e-048839010C0036341
DiseaseFanconi anemia (is_implicated_in)

BRCA1 BRCA2

4.07e-0410902DOID:13636 (is_implicated_in)
DiseaseOligospermia

NR0B1 PIWIL4

5.95e-0412902C0028960
DiseaseBenign tumor of pancreas

BRCA1 BRCA2

7.02e-0413902C0347284
Diseasecreatine kinase measurement

MYPN NEB GAB2

7.88e-0459903EFO_0004534
DiseaseHereditary Breast and Ovarian Cancer Syndrome

BRCA1 BRCA2

8.17e-0414902C0677776
Diseasenasopharynx carcinoma (is_implicated_in)

BRCA1 CHRNA5

9.41e-0415902DOID:9261 (is_implicated_in)
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

CDY2A CDY1

1.07e-0316902C1839071
DiseaseSpermatogenic failure, Y-linked, 2

CDY2A CDY1

1.07e-0316902cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

CDY2A CDY1

1.07e-0316902415000
Diseasehemoglobin A1 measurement

FNDC3B ABCC1 MGAM FZR1 RPS6KA1 PAK2 GAB2

1.07e-03520907EFO_0007629
Diseasechronic obstructive pulmonary disease

FNDC3B RANBP10 MYPN DLG2 IL1RL1 MPHOSPH9 CHRNA5 GAB2

1.21e-03688908EFO_0000341
DiseasePancreatic carcinoma

BRCA1 BRCA2

1.52e-0319902C0235974
DiseaseMalignant neoplasm of breast

FNDC3B ABCC1 PTPRC BRCA1 BRCA2 DYNC2H1 TREM1 ANKRD34A DTX3L RGS2

1.61e-0310749010C0006142
Diseasesusceptibility to strep throat measurement

PCLO LAMA3 IL1RL1

1.64e-0376903EFO_0008408
DiseaseAdenocarcinoma of prostate

BRCA1 BRCA2

1.69e-0320902C0007112
DiseaseBREAST CANCER

BRCA1 BRCA2

1.86e-0321902114480
Diseaseage at menarche

FNDC3B NRBF2 BRCA1 SKOR2 DLG2 OSBP2 GAB2

2.29e-03594907EFO_0004703
Diseasebody fat percentage, coronary artery disease

MIA3 DYNC2H1

2.43e-0324902EFO_0001645, EFO_0007800
Diseasepallidum volume

DLG2 HS3ST4

2.64e-0325902EFO_0006933
DiseaseFanconi Anemia

BRCA1 BRCA2

2.64e-0325902C0015625
Diseasebreast cancer (implicated_via_orthology)

BRCA1 BRCA2

2.64e-0325902DOID:1612 (implicated_via_orthology)
Diseaserefractive error, age at onset, Myopia

FNDC3B KCNMA1 DLG2 GRIN2B

2.93e-03193904EFO_0004847, HP_0000545, MONDO_0004892

Protein segments in the cluster

PeptideGeneStartEntry
NSTQNVYKIPPTTTK

TREM1

146

Q9NP99
TVYATTRKPPAQSSK

FAM229B

61

Q4G0N7
SCPQPLNETSYSKIA

BDP1

1796

A6H8Y1
TKNAPSLPSRTCYKT

AKAP2

751

Q9Y2D5
KPKPSSNTKNYTGES

CCDC117

221

Q8IWD4
TKANYSKNSPKTPVT

CDY1

86

Q9Y6F8
TKANYSKNSPKTPVT

CDY2A

86

Q9Y6F7
KPNIYDIPKATSSVS

CASS4

346

Q9NQ75
LQKKPSTEQPLYSSS

AZIN2

341

Q96A70
NSTPPPTQLSKIKYS

PPP2R5D

61

Q14738
SSSSSNSSKLPPVCY

BTBD3

36

Q9Y2F9
VDLQPYPTSSTKQSK

AGGF1

256

Q8N302
YNLKKPHSQPSFCSS

DNAI1

411

Q9UI46
SSSPEKILSPFSQKY

DMXL1

916

Q9Y485
SQCPALQTSSPYKQA

DISP2

1226

A7MBM2
SGTKKTRQYLNSPPS

ANKRD34A

151

Q69YU3
YIKPITKCESSTQTN

CFAP206

506

Q8IYR0
TKSKQNHSKYPAPSS

RANBP10

396

Q6VN20
ADSYSPNLPKSTTKA

PTPN22

321

Q9Y2R2
TKSVPKCTDPTYNEI

PIK3C2G

1381

O75747
YSQSKNIPLSQPATT

HIPK2

51

Q9H2X6
LNYTKGATSSKPETP

LAMA3

2501

Q16787
STPSQCTKRYVITNP

KCNMA1

1146

Q12791
PSQTSPTVTYDSNLK

MGAM

921

O43451
SGSTSNTPYTPLEKK

KIAA1109

1576

Q2LD37
QSPQYLSATSPPKDK

PCLO

3576

Q9Y6V0
YDSKKPSPCEFINTT

LPO

346

P22079
KSVSYEQCKPVSVTP

MPHOSPH9

931

Q99550
PKKCGPYISSVTSQS

INSIG2

11

Q9Y5U4
VPQPKHASQKTVYSS

ARHGAP32

1461

A7KAX9
SPSSDGKQKTVYQTL

OSBP2

766

Q969R2
TISSNPYENQKIPTK

PEG3

751

Q9GZU2
GQSPLSQKYSPSTEK

NRBF2

111

Q96F24
SQKYSPSTEKCLPEI

NRBF2

116

Q96F24
STDTEYSQPEQKLPK

PLEKHH2

676

Q8IVE3
YSQPEQKLPKTCSSS

PLEKHH2

681

Q8IVE3
SAKQTYAAPKAPEAT

NR0B1

86

P51843
QIACSPPYSSKTRSQ

SLC51A

281

Q86UW1
DSNTVKQKYLSFTPP

PAK2

131

Q13177
TSQKSSEYPISQNPE

BRCA1

1456

P38398
PKKITSSSAIYDNPN

DCP1B

181

Q8IZD4
SPYSLSPVSNKSQKL

FZR1

146

Q9UM11
CKTKVYPDNLPTTSV

GALNT1

106

Q10472
KKSIFPYSVSLPQSC

DYNC2H1

3961

Q8NCM8
TPPANYKSSCTIDVT

CHRNA5

161

P30532
TVSGSEKNSKIYCPT

IL1RL1

121

Q01638
CTFPPKSLDTTTQQK

ICE2

926

Q659A1
NSSYIPTKQFETCSK

DOCK9

601

Q9BZ29
ETAKSPATCYTNQSP

BRCA2

1646

P51587
SPSEPETKAEQKSNY

DTX3L

221

Q8TDB6
LNSPPSSIYKSSCTT

FNDC3B

206

Q53EP0
KKSVSPSASPVVCYQ

FSTL1

101

Q12841
SSLASSQEPEPKKYG

DENND2C

246

Q68D51
YFLPTKISTKTPNAS

DNAH14

3431

Q0VDD8
DNSCPNSKAPVLSKY

LUZP1

591

Q86V48
SNPNYDKTSAPITCE

DYNC1H1

1986

Q14204
NTPYGTASEPSEKAK

KCTD5

211

Q9NXV2
YEQKVSPVSASSPKE

KIAA1210

1306

Q9ULL0
PVYSTVNKLCDKPAS

DLG2

346

Q15700
KVDPLCSSKTYTVSP

GPRIN1

216

Q7Z2K8
CSSKTYTVSPRKEDP

GPRIN1

221

Q7Z2K8
TYSTKSQKDVQSPAP

SLC19A3

461

Q9BZV2
SDYTQTLSKKPEIPT

HS3ST4

296

Q9Y661
KAYSPKETCNPSDTF

RP1

1266

P56715
VYSSKDPAQPKESSK

ABCC1

276

P33527
NSPAPKKSTGSVDYL

GAB2

601

Q9UQC2
TTAPEKYRVKPSNSS

MOSPD2

366

Q8NHP6
SSIPIPSSNSTEKKY

TAS2R40

171

P59535
SYFLQNSSTPGKPKT

RGS2

46

P41220
NQTPTKKYDGYTSCP

SQOR

366

Q9Y6N5
ETKSSYIAASTAKPP

TRMT1L

211

Q7Z2T5
LKSPMPSSTTQKDSY

SPAG8

321

Q99932
KKSVSSENPTYPSAP

SH3D19

146

Q5HYK7
TQPNTKYTFKITVSP

TAB2

456

Q9NYJ8
PDSKQGKPQSATDYS

MIA3

421

Q5JRA6
NYPPTITESKSNEAT

LSAMP

216

Q13449
KTQPTYPSVKSSQCH

NKRF

411

O15226
ASSVEYKSSNKQPKP

SLITRK3

321

O94933
SIKKYLSSDCPVPSQ

PIWIL4

561

Q7Z3Z4
ARSPCKSPKGYTNSE

SRSF12

221

Q8WXF0
ECVSSNPYSKPSSKS

CKAP2L

106

Q8IYA6
NPYSKPSSKSFQQCE

CKAP2L

111

Q8IYA6
AKAFKSPLSSPQQTQ

CNOT11

331

Q9UKZ1
ESSPKQPTNPYASSK

TGDS

156

O95455
PTKNELSQSPKKDSY

XIRP2

2961

A4UGR9
YKGQTRKATTNPPCT

TRIM55

446

Q9BYV6
SDNPSPSSSRKVKSY

SRRM5

231

B3KS81
TSAKNTLSTPLPKAY

SYCP1

841

Q15431
DCITKSISPYPKTSS

SYCP2

1131

Q9BX26
PSLEEQPSYKDSQKT

SKOR2

861

Q2VWA4
VPQSSHSKEEPYKCS

ZNF445

751

P59923
QSSYPGDNTKPKTTE

ZNF543

76

Q08ER8
GTQTSPVPRKKTYQC

ZNF423

1156

Q2M1K9
TTPSKPTCDEKYANI

PTPRC

221

P08575
SSKIPAVTYPKNEST

TRMT10C

41

Q7L0Y3
SSATQSKPTPVKPNY

WDR5

21

P61964
PPAPKSTYESNTKQL

TIA1

186

P31483
TYSALNSSKPTPQLK

RPS6KA1

701

Q15418
TSSKESPQEAKRPQY

MYPN

126

Q86TC9
ASTTKYPQSPTNSKA

GRIN2B

1276

Q13224
EKTKGQPYASTTDTP

NEB

106

P20929