Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR8H2 OR5M10 OR5M1 OR13C3 MCHR2 NPSR1 OR13C6P FZD4 TAS2R4 OR4S1 OR1P1 ADGRF3 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 GRPR OR3A1 OR51I1 MTNR1A OR4C46 MRGPRX4 OR13C7

9.63e-0988418328GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR8H2 OR5M10 OR5M1 OR13C3 MCHR2 NPSR1 OR13C6P FZD4 TAS2R4 OR4S1 NRXN3 PTPRH PTPRO OR1P1 ADGRF3 KIR2DL4 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 NFAM1 GRPR OR3A1 IGF2R OR51I1 MTNR1A OR4C46 MRGPRX4 OR13C7

6.66e-08135318334GO:0004888
GeneOntologyMolecularFunctionolfactory receptor activity

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

4.99e-0743118317GO:0004984
GeneOntologyMolecularFunctionneuropeptide receptor activity

NPSR1 NMBR NPBWR1 NPBWR2 GRPR MRGPRX4

8.76e-06531836GO:0008188
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

MCHR2 NPSR1 NMBR NPBWR1 NPBWR2 GRPR MRGPRX4

2.28e-041331837GO:0008528
GeneOntologyMolecularFunctionbombesin receptor activity

NMBR GRPR

2.49e-0431832GO:0004946
GeneOntologyMolecularFunctionpeptide receptor activity

MCHR2 NPSR1 NMBR NPBWR1 NPBWR2 GRPR MRGPRX4

3.12e-041401837GO:0001653
GeneOntologyMolecularFunctionneuropeptide binding

NPBWR1 NPBWR2 GRPR MRGPRX4

3.56e-04371834GO:0042923
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RHOU HERC1 AGAP4 TNS3 ARAP2 IQSEC3 STXBP5L MADD AKAP13 RPGR AGAP7P FGD6 AGAP6

8.33e-0450718313GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RHOU HERC1 AGAP4 TNS3 ARAP2 IQSEC3 STXBP5L MADD AKAP13 RPGR AGAP7P FGD6 AGAP6

8.33e-0450718313GO:0030695
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR8H2 OR5M10 PDE3A OR5M1 OR13C3 MCHR2 NPSR1 ITGB1 OR13C6P FZD4 TAS2R4 OR4S1 OR1P1 ADGRF3 ARRDC3 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 GRPR OR3A1 GTF2H2 IGF2R OR51I1 MTNR1A OR4C46 MRGPRX4 AKAP13 OR13C7

1.64e-07139519034GO:0007186
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

5.62e-0743219017GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P TAS2R4 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

6.04e-0748519018GO:0050907
GeneOntologyBiologicalProcesssensory perception of smell

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

1.54e-0646519017GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P TAS2R4 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

1.82e-0652419018GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P TAS2R4 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

3.32e-0654719018GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P TAS2R4 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

7.80e-0658219018GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR8H2 OR5M10 OR5M1 OR13C3 NAIP OR13C6P TAS2R4 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

4.08e-0572219019GO:0051606
GeneOntologyBiologicalProcesssensory perception

OR8H2 OR5M10 OR5M1 OR13C3 OR13C6P FZD4 TAS2R4 OR4S1 ATXN7 OR1P1 USP53 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 PKHD1L1 OR3A1 OR51I1 OR4C46 PAX3 RPGR OR13C7

5.23e-05107219024GO:0007600
GeneOntologyBiologicalProcessplatelet maturation

SLFN14 FGG

8.44e-0521902GO:0036345
GeneOntologyBiologicalProcessneuropeptide signaling pathway

MCHR2 NPSR1 NMBR NPBWR1 NPBWR2 GRPR MRGPRX4

1.53e-041241907GO:0007218
GeneOntologyCellularComponentT cell receptor complex

TRAV10 TRAV6 TRBV24-1 TRBV19 TRBV6-9 TRBV6-5 TRBV6-4 TRBV6-1 TRAV27

2.22e-051631949GO:0042101
GeneOntologyCellularComponentplasma membrane signaling receptor complex

TRAV10 ITGB1 ITGB8 TRAV6 BIRC2 TRBV24-1 TRBV19 TRBV6-9 TRBV6-5 TRBV6-4 TRBV6-1 TRAV27

1.11e-0435019412GO:0098802
Domain7tm_1

OR8H2 OR5M10 OR5M1 OR13C3 MCHR2 NPSR1 OR4S1 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR5A2 OR2J1 OR5M11 GRPR OR3A1 OR51I1 MTNR1A OR4C46 MRGPRX4

1.86e-0667717721PF00001
DomainG_PROTEIN_RECEP_F1_1

OR8H2 OR5M10 OR5M1 OR13C3 MCHR2 NPSR1 OR4S1 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR5A2 OR2J1 OR5M11 GRPR OR3A1 OR51I1 MTNR1A OR4C46 MRGPRX4

2.24e-0668517721PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8H2 OR5M10 OR5M1 OR13C3 MCHR2 NPSR1 OR4S1 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR5A2 OR2J1 OR5M11 GRPR OR3A1 OR51I1 MTNR1A OR4C46 MRGPRX4

2.57e-0669117721PS50262
DomainGPCR_Rhodpsn

OR8H2 OR5M10 OR5M1 OR13C3 MCHR2 NPSR1 OR4S1 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR5A2 OR2J1 OR5M11 GRPR OR3A1 OR51I1 MTNR1A OR4C46 MRGPRX4

2.62e-0669217721IPR000276
DomainGPCR_Rhodpsn_7TM

OR8H2 OR5M10 OR5M1 OR13C3 MCHR2 NPSR1 OR4S1 NMBR NPBWR1 NPBWR2 OR8J3 OR2B2 OR5A2 OR5M11 GRPR OR3A1 OR51I1 MTNR1A OR4C46 MRGPRX4

5.91e-0667017720IPR017452
DomainPSI_integrin

ITGB1 ITGB8 MEGF8

6.74e-0591773PF17205
DomainIntegin_beta_N

ITGB1 ITGB8 MEGF8

6.74e-0591773IPR033760
DomainNeuropept_B/W_rcpt

NPBWR1 NPBWR2

8.93e-0521772IPR009150
DomainOlfact_rcpt

OR8H2 OR5M10 OR5M1 OR13C3 OR4S1 OR8J3 OR2B2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46

9.90e-0539317713IPR000725
DomainZnf_RING/FYVE/PHD

KDM5B TRIM49C KMT2C PDZRN4 TRIM49 UBR2 HDAC6 TRIM51 ZNF521 BIRC2 RUFY1 RNF139 TRIM49B FGD6

1.26e-0445917714IPR013083
Domain-

DMBT1 CDCP1 MEGF8 SCUBE3 DCBLD2

1.31e-045217752.60.120.290
DomainCUB

DMBT1 CDCP1 MEGF8 SCUBE3 DCBLD2

1.43e-04531775PS01180
DomainArfGap

AGAP4 ARAP2 AGAP7P AGAP6

1.54e-04291774SM00105
DomainARFGAP

AGAP4 ARAP2 AGAP7P AGAP6

1.54e-04291774PS50115
DomainArfGap

AGAP4 ARAP2 AGAP7P AGAP6

1.54e-04291774PF01412
DomainArfGAP

AGAP4 ARAP2 AGAP7P AGAP6

1.54e-04291774IPR001164
DomainCUB_dom

DMBT1 CDCP1 MEGF8 SCUBE3 DCBLD2

2.03e-04571775IPR000859
DomainBombsn_rcpt-like

NMBR GRPR

2.66e-0431772IPR001556
DomainSPRY

TRIM49C BTNL3 HERC1 TRIM49 TRIM51 TRIM49B

2.72e-04941776PF00622
DomainSPRY_dom

TRIM49C BTNL3 HERC1 TRIM49 TRIM51 TRIM49B

2.72e-04941776IPR003877
DomainB30.2/SPRY

TRIM49C BTNL3 HERC1 TRIM49 TRIM51 TRIM49B

2.88e-04951776IPR001870
DomainB302_SPRY

TRIM49C BTNL3 HERC1 TRIM49 TRIM51 TRIM49B

2.88e-04951776PS50188
DomainZnf_RING

TRIM49C KMT2C PDZRN4 TRIM49 UBR2 TRIM51 BIRC2 RUFY1 GTF2H2 RNF139 TRIM49B

2.89e-0432617711IPR001841
Domain-

KDM5B TRIM49C KMT2C PDZRN4 TRIM49 UBR2 HDAC6 TRIM51 ZNF521 RUFY1 RNF139 TRIM49B FGD6

3.63e-04449177133.30.40.10
DomainUbiquitin_3

USP32 USP4

5.29e-0441772PF14836
DomainUb_USP-typ

USP32 USP4

5.29e-0441772IPR028135
DomainButyrophylin

TRIM49C BTNL3 TRIM49 TRIM51 TRIM49B

5.31e-04701775IPR003879
Domain-

KBTBD2 KLHL38 MEGF8 GAN

1.10e-034817742.120.10.80
DomainConA-like_dom

TRIM49C NRXN3 BTNL3 HERC1 TRIM49 TRIM51 FAT3 TRIM49B

1.18e-032191778IPR013320
DomainCUB

DMBT1 MEGF8 SCUBE3 DCBLD2

1.18e-03491774PF00431
DomainCUB

DMBT1 MEGF8 SCUBE3 DCBLD2

1.28e-03501774SM00042
DomainLCCL

CRISPLD2 DCBLD2

1.31e-0361772PS50820
DomainDUSP

USP32 USP4

1.31e-0361772PF06337
DomainDUSP

USP32 USP4

1.31e-0361772SM00695
DomainLCCL

CRISPLD2 DCBLD2

1.31e-0361772SM00603
DomainLCCL

CRISPLD2 DCBLD2

1.31e-0361772PF03815
DomainLCCL

CRISPLD2 DCBLD2

1.31e-0361772IPR004043
Domain-

CRISPLD2 DCBLD2

1.31e-03617722.170.130.20
DomainSPRY

TRIM49C BTNL3 HERC1 TRIM49 TRIM49B

1.43e-03871775SM00449
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8H2 OR5M10 OR5M1 OR13C3 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46

2.25e-0641711915M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR8H2 OR5M10 OR5M1 OR13C3 TAS2R4 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46

8.67e-0563611916M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR8H2 OR5M10 OR5M1 OR13C3 OR4S1 OR8J3 OR2B2 OR5A2 OR5M11 OR3A1 OR51I1 OR4C46

1.09e-0438911912M14091
Pubmed

Identification of a genomic reservoir for new TRIM genes in primate genomes.

TRIM49C TRIM49 TRIM51 TRIM49B TRIM51G

5.74e-0819195522144910
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR8H2 OR5M10 OR5M1 OR13C3 OR1P1 OR8J3 OR2B2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

7.56e-083401951311875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8H2 OR5M10 OR5M1 OR13C3 OR1P1 OR8J3 OR2B2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

7.56e-083401951311802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR8H2 OR5M10 OR5M1 OR13C3 OR1P1 OR8J3 OR2B2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

8.37e-083431951332295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR8H2 OR5M10 OR5M1 OR13C3 OR1P1 OR8J3 OR2B2 OR2J1 OR5M11 OR3A1 OR51I1 OR4C46 OR13C7

9.26e-083461951314611657
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ACACB ITGB1 GAB2 TASOR2 EFTUD2 PTPN13 FAM135A DYNC1H1 IGSF3 ARAP2 KBTBD2 RUFY1 PKHD1L1 PCF11 IGF2R TMF1 RPGR DEPDC7

4.58e-077771951835844135
Pubmed

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

TRIM49C TRIM49 TRIM51 TRIM49B

1.25e-0615195419703589
Pubmed

Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors.

TRBV24-1 TRBV6-9 TRBV6-1

1.72e-06519533865189
Pubmed

The human olfactory receptor gene family.

OR8H2 OR5M10 OR5M1 OR13C3 OR4S1 OR1P1 OR8J3 OR2B2 OR4Q2 OR5A2 OR2J1 OR5M11 OR3A1 OR51I1

2.57e-065411951414983052
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

CCPG1 ACACB TASOR2 ARRDC3 CAMTA1 VASP DYNC1H1 USP53 NBPF20 STON2 AKAP13 ZMYM5

6.40e-064301951235044719
Pubmed

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.

MED14 PPARGC1A MED16

1.42e-059195314636573
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP4 AGAP7P AGAP6

1.42e-059195312640130
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1B MED14 MAST2 CABLES1 MAPK8IP3 KMT2C HERC1 DYNC1H1 IGSF3 PITPNM2 RARG RTTN FRYL MADD MYOF IGF2R MEGF8 PCNX1 AKAP13

1.64e-0511051951935748872
Pubmed

The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.

TRBV24-1 TRBV19 TRBV6-9 TRBV6-5 TRBV6-4 TRBV6-1

1.65e-059519568650574
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP4 AGAP7P AGAP6

2.02e-0510195320664521
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ITGB1 USP32 FAM135A TNS3 IGSF3 ARAP2 USP53 CDCP1 KLHL38 IGF2R STON2 FGD6 DCBLD2

2.20e-055691951330639242
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

AP2A2 CAMTA1 HDAC6 FRYL PCF11 FAM169A

2.21e-05100195610048485
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TCAF1 EFTUD2 SHROOM4 AP2A2 TXNDC16 FAM135A PDZRN4 GPAM PCF11 MYOF FAM169A FGD6

2.48e-054931951215368895
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP4 AGAP7P AGAP6

2.77e-0511195315381706
Pubmed

The genomic structure of human V beta 6 T cell antigen receptor genes.

TRBV6-9 TRBV6-4 TRBV6-1

2.77e-051119531660526
Pubmed

Two distinct bombesin receptor subtypes are expressed and functional in human lung carcinoma cells.

NMBR GRPR

3.13e-05219521655761
Pubmed

The integrin β1 subunit regulates paracellular permeability of kidney proximal tubule cells.

ITGB1 PPARGC1A

3.13e-052195224509849
Pubmed

MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity.

KMT2C TNS3

3.13e-052195233824309
Pubmed

Molecular cloning and characterization of receptors for the mammalian bombesin-like peptides.

NMBR GRPR

3.13e-05219528391296
Pubmed

Long noncoding RNA LINC00052 suppressed the proliferation, migration and invasion of glioma cells by upregulating KLF6.

LINC00052 KLF6

3.13e-052195231210314
Pubmed

Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB.

SLC38A3 SGK1

3.13e-052195212788082
Pubmed

Deletion of hensin/DMBT1 blocks conversion of beta- to alpha-intercalated cells and induces distal renal tubular acidosis.

ITGB1 DMBT1

3.13e-052195221098262
Pubmed

Integrin β1 is critical for gastrin-releasing peptide receptor-mediated neuroblastoma cell migration and invasion.

ITGB1 GRPR

3.13e-052195223889963
Pubmed

Full-length PGC-1α salvages the phenotype of a mouse model of human neuropathy through mitochondrial proliferation.

PPARGC1A DYNC1H1

3.13e-052195223900073
Pubmed

CLIC4 regulates cell adhesion and β1 integrin trafficking.

ITGB1 CLIC4

3.13e-052195225344254
Pubmed

The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.

NPBWR1 NPBWR2

3.13e-05219527590751
Pubmed

Evolution of the B7 family: co-evolution of B7H6 and NKp30, identification of a new B7 family member, B7H7, and of B7's historical relationship with the MHC.

VSIR HHLA2

3.13e-052195222488247
Pubmed

Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis.

ERN1 PPARGC1A

3.13e-052195236123394
Pubmed

Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene.

AP2A2 MUC6

3.13e-052195231748784
Pubmed

Different clinical significance of novel B7 family checkpoints VISTA and HHLA2 in human lung adenocarcinoma.

VSIR HHLA2

3.13e-052195235187955
Pubmed

Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.

OR13C3 OR13C6P OR13C7

3.68e-0512195312906860
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP4 AGAP7P AGAP6

4.76e-0513195327713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP4 AGAP7P AGAP6

6.04e-0514195322453919
Pubmed

Retinoic acid receptor gamma impacts cellular adhesion, Alpha5Beta1 integrin expression and proliferation in K562 cells.

ITGB1 RARG

9.35e-053195228552962
Pubmed

Regulation of inside-out β1-integrin activation by CDCP1.

ITGB1 CDCP1

9.35e-053195229511352
Pubmed

Faster lipid β-oxidation rate by acetyl-CoA carboxylase 2 inhibition alleviates high-glucose-induced insulin resistance via SIRT1/PGC-1α in human podocytes.

ACACB PPARGC1A

9.35e-053195233957017
Pubmed

Functional properties of two bombesin-like peptide receptors revealed by the analysis of mice lacking neuromedin B receptor.

NMBR GRPR

9.35e-05319529920658
Pubmed

Impaired integrin-mediated adhesion contributes to reduced barrier properties in VASP-deficient microvascular endothelium.

ITGB1 VASP

9.35e-053195219347869
Pubmed

Long non-coding RNA CRNDE promotes gallbladder carcinoma carcinogenesis and as a scaffold of DMBT1 and C-IAP1 complexes to activating PI3K-AKT pathway.

DMBT1 BIRC2

9.35e-053195227637083
Pubmed

The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited.

RARG BIRC2

9.35e-053195228871172
Pubmed

Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization.

NAIP BIRC2

9.35e-053195229518103
Pubmed

Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice.

NMBR GRPR

9.35e-053195223826298
Pubmed

Angiopoietin-2 promotes ER+ breast cancer cell survival in bone marrow niche.

ITGB1 ANGPT2

9.35e-053195227353038
Pubmed

Cross-inhibition of NMBR and GRPR signaling maintains normal histaminergic itch transmission.

NMBR GRPR

9.35e-053195225209280
Pubmed

Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8.

NPBWR1 NPBWR2

9.35e-053195212130646
Pubmed

DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression.

PPARGC1A NR0B1

9.35e-053195219651776
Pubmed

Cloning and expression of the neuromedin B receptor and the third subtype of bombesin receptor genes in the mouse.

NMBR GRPR

9.35e-05319529262170
Pubmed

Extracellular Vesicle-Derived circITGB1 Regulates Dendritic Cell Maturation and Cardiac Inflammation via miR-342-3p/NFAM1.

ITGB1 NFAM1

9.35e-053195235615580
Pubmed

Expression and characterization of cloned human bombesin receptors.

NMBR GRPR

9.35e-05319527838118
Pubmed

The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation.

TRBV19 TRAV27

9.35e-053195221081917
Pubmed

Role of bombesin (BN)-like peptides/receptors in emotional behavior by comparison of three strains of BN-like peptide receptor knockout mice.

NMBR GRPR

9.35e-053195211803457
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KDM5B HIVEP1 MAST2 GAB2 PTPN13 TNS3 ARAP2 USP53 RBBP7 FRYL MADD MEGF8 GAN AKAP13 FGD6

1.14e-048611951536931259
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TCAF1 ITGB1 PPARGC1A KMT2C PTPN13 CAMTA1 HERC1 PARPBP FAM135A PARP12 HDAC6 AHCTF1 FRYL CDCP1 MADD IGF2R TIA1

1.42e-0410841951711544199
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

CCPG1 P4HA3 ITGB1 ITGB8 TXNDC16 SLC27A3 IGSF3 UBR2 CTSA RUFY1 TXNDC11 MADD MYOF IGF2R MEGF8 TTI1 DSEL DCBLD2

1.58e-0412011951835696571
Pubmed

In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signaling.

ITGB1 CDCP1

1.86e-044195223208492
Pubmed

IAPs: more than just inhibitors of apoptosis proteins.

NAIP BIRC2

1.86e-044195218414036
Pubmed

Mena binds α5 integrin directly and modulates α5β1 function.

ITGB1 VASP

1.86e-044195222908313
Pubmed

The peptidergic control circuit for sighing.

NMBR GRPR

1.86e-044195226855425
Pubmed

Bombesin-like peptide receptor gene expression, regulation, and function in fetal murine lung.

NMBR GRPR

1.86e-044195212959933
Pubmed

The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.

AP2A2 CD22

1.86e-044195212646615
Pubmed

Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8.

NPBWR1 NPBWR2

1.86e-044195212719537
Pubmed

Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.

PTPRH PTPRO

1.86e-044195220398064
Pubmed

Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis.

ITGB1 ANGPT2

1.86e-044195238775153
Pubmed

Expression of the inhibitor of apoptosis protein family in multiple sclerosis reveals a potential immunomodulatory role during autoimmune mediated demyelination.

NAIP BIRC2

1.86e-044195218566024
Pubmed

The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex.

ERN1 PPARGC1A

1.86e-044195221284983
Pubmed

G protein receptors 7 and 8 are expressed in human adrenocortical cells, and their endogenous ligands neuropeptides B and w enhance cortisol secretion by activating adenylate cyclase- and phospholipase C-dependent signaling cascades.

NPBWR1 NPBWR2

1.86e-044195215797961
Pubmed

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.

NAIP BIRC2

1.86e-04419528552191
Pubmed

Angiopoietin-2-integrin α5β1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance.

ITGB1 ANGPT2

1.86e-044195232532986
Pubmed

Distinct roles of NMB and GRP in itch transmission.

NMBR GRPR

1.86e-044195229133874
Pubmed

Claudin-4 localization in epithelial ovarian cancer.

ITGB1 IGSF3 IGF2R DCBLD2

2.43e-0454195436237976
Pubmed

Lineage-specific biology revealed by a finished genome assembly of the mouse.

TRIM49C TRIM49 TRIM51 TRIM49B

2.61e-0455195419468303
Pubmed

Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin.

PTPRH PTPRO

3.09e-045195228926625
Pubmed

Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8.

NPBWR1 NPBWR2

3.09e-045195212401809
Pubmed

Retinoic acid induces down-regulation of Wnt-3a, apoptosis and diversion of tail bud cells to a neural fate in the mouse embryo.

RARG PAX3

3.09e-045195210473117
Pubmed

Influenza A virus uses the aggresome processing machinery for host cell entry.

DYNC1H1 HDAC6

3.09e-045195225342804
Pubmed

Protein kinase CK2 regulates the formation and clearance of aggresomes in response to stress.

DYNC1H1 HDAC6

3.09e-045195221486957
Pubmed

Correlation of SMN2, NAIP, p44, H4F5 and Occludin genes copy number with spinal muscular atrophy phenotype in Tunisian patients.

NAIP GTF2H2

3.09e-045195221821450
Pubmed

Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.

HDAC6 MYOF

3.09e-045195224687993
Pubmed

A population-based study of genotypic and phenotypic variability in children with spinal muscular atrophy.

BIRC2 GTF2H2

3.09e-045195219154529
Pubmed

SARS-CoV-2 nucleocapsid protein promotes self-deacetylation by inducing HDAC6 to facilitate viral replication.

HDAC6 TIA1

3.09e-045195239135075
Pubmed

Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol.

PPARGC1A NR0B1

3.09e-045195218160712
Pubmed

Gln-362 of angiopoietin-2 mediates migration of tumor and endothelial cells through association with α5β1 integrin.

ITGB1 ANGPT2

3.09e-045195225237190
Pubmed

Homozygous MED25 mutation implicated in eye-intellectual disability syndrome.

MED14 MED16

3.09e-045195225792360
Pubmed

An investigation into the human serum "interactome".

CABLES1 CAMTA1 TNS3 PDZRN4 CDCP1 FAM169A

3.19e-04162195615174051
Pubmed

A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus.

RARG TG

4.62e-04619528597630
Pubmed

Angiopoietin-2 regulates cortical neurogenesis in the developing telencephalon.

ITGB1 ANGPT2

4.62e-046195221127017
Pubmed

The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites.

PTPRH PTPRO

4.62e-046195226063811
Pubmed

Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway.

ITGB1 ANGPT2

4.62e-046195216424009
Pubmed

Sequence of a 131-kb region of 5q13.1 containing the spinal muscular atrophy candidate genes SMN and NAIP.

NAIP GTF2H2

4.62e-04619529503025
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

NRXN3 CACNA1B

4.62e-046195212827191
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1B ARRDC3 CAMTA1 DYNC1H1 ARAP2 UBR2 IQSEC3 MADD MEGF8

5.20e-04407195912693553
Pubmed

Integrin expression patterns during early limb muscle development in the mouse.

ITGB1 PAX3

6.45e-047195214516674
Pubmed

High-resolution genetic and physical map of the Lgn1 interval in C57BL/6J implicates Naip2 or Naip5 in Legionella pneumophila pathogenesis.

NAIP GTF2H2

6.45e-047195210958634
Pubmed

BNP facilitates NMB-encoded histaminergic itch via NPRC-NMBR crosstalk.

NMBR GRPR

6.45e-047195234919054
Pubmed

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.

CABLES1 ARRDC3

6.45e-047195225038754
CytobandEnsembl 112 genes in cytogenetic band chr7q34

TAS2R4 PARP12 TBXAS1 TRBV24-1 TRBV19 TRBV6-5 TRBV6-4 TRBV6-1

1.41e-061851958chr7q34
CytobandEnsembl 112 genes in cytogenetic band chr11q14

TRIM49C GAB2 FZD4 TRIM49 FAT3 PCF11 DDIAS

5.11e-061561957chr11q14
Cytoband7q34

PARP12 TRBV24-1 TRBV19 TRBV6-9 TRBV6-5 TRBV6-4 TRBV6-1

7.99e-0616719577q34
Cytoband11q12.1

OR8H2 OR5M10 OR5M1 OR8J3 OR5A2 OR5M11

6.93e-05161195611q12.1
CytobandEnsembl 112 genes in cytogenetic band chr11q12

OR8H2 OR5M10 OR5M1 OR8J3 TRIM51 OR5A2 OR5M11

7.28e-043451957chr11q12
Cytoband11p11.12

OR4C46 TRIM49B TRIM51G

7.67e-0442195311p11.12
Cytoband20q13.1

SLC2A10 CTSA

7.90e-0410195220q13.1
GeneFamilyNeuropeptide receptors

NPSR1 NPBWR1 NPBWR2

5.47e-05101423854
GeneFamilyT cell receptor beta locus at 7q34

TRBV24-1 TRBV19 TRBV6-9 TRBV6-5 TRBV6-4 TRBV6-1

6.32e-05871426372
GeneFamilyArfGAPs

AGAP4 ARAP2 AGAP7P AGAP6

1.25e-04331424395
GeneFamilyBombesin receptors

NMBR GRPR

1.83e-0431422222
GeneFamilyOlfactory receptors, family 13

OR13C3 OR13C6P OR13C7

7.49e-04231423162
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM49C TRIM49 TRIM51 TRIM49B TRIM51G

9.16e-0495142559
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

GAB2 AGAP4 ARAP2 AKAP13 AGAP7P FGD6 AGAP6

1.22e-032061427682
GeneFamilyRing finger proteins|Baculoviral IAP repeat containing|Caspase recruitment domain containing

NAIP BIRC2

1.66e-0381422419
GeneFamilyAdenosine receptors|V-set domain containing

VSIR BTNL3 IGLON5 IGSF3 ICOSLG HHLA2

1.83e-031631426590
GeneFamilyCD molecules|Integrin beta subunits

ITGB1 ITGB8

2.13e-03914221159
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

ITGB8 PTPN13 NRXN3 ARAP2 CLIC4 RPGR DEPDC7 MEGF10

7.38e-071691928a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3A SLFN14 CACNA1B CLIC4 CTSA RUFY1 PKHD1L1 STON2

1.46e-061851928c985a4b184d382a79aaff07f81c0efede2c2d493
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3A SLFN14 CACNA1B CLIC4 CTSA RUFY1 PKHD1L1 STON2

1.46e-061851928d0d0e000ebe1fc35a987930ceaf7e3369e0c694c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3A SLFN14 CACNA1B CLIC4 CTSA RUFY1 PKHD1L1 STON2

1.46e-0618519280ca99fcbd30c454bcdc2aa5265a0e4dba25666ea
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3A SLFN14 CACNA1B CLIC4 CTSA RUFY1 PKHD1L1 STON2

1.46e-0618519280f722ffcc3e78d5c6b1b79d31d00929801a993f1
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

TASOR2 KMT2C HERC1 DYNC1H1 ARAP2 AHCTF1 IGF2R PCNX1

1.64e-061881928ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SHROOM4 TNS3 TBXAS1 CLIC4 CD22 STON2 MEGF10

1.85e-061911928a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

NAIP AP2A2 MPPED2 TNS3 ARAP2 TBXAS1 CTSA MUC6

2.08e-061941928c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

NAIP AP2A2 MPPED2 TNS3 ARAP2 TBXAS1 CTSA MUC6

2.16e-0619519285e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Nptxr_(Reuniens_thalamic_nucleus?)|Thalamus / BrainAtlas - Mouse McCarroll V32

NR0B1 SLURP1 POM121L2 GDF3 MTNR1A

2.69e-06511925a1ee951bc909502b64fa9a7361eaccf05dabbcc7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRO DMBT1 TNS3 IGSF3 ICOSLG GRPR KRTAP13-1

5.04e-061551927cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDE3A PTPRO TNS3 PDZRN4 CRISPLD2 CLIC4 GRPR

7.60e-061651927c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

ITGB8 NRXN3 ARAP2 CLIC4 RPGR DEPDC7 MEGF10

7.60e-0616519276ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

ITGB8 NRXN3 ARAP2 CLIC4 RPGR DEPDC7 MEGF10

8.55e-061681927c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellwk_20-22-Hematologic-Meg-ery-Megakaryocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PDE3A SLFN14 TBXAS1 CTSA RUFY1 PKHD1L1 STON2

9.23e-061701927eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCellwk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TMPRSS5 NMBR ITIH6 SLC38A3 TNS3 RARG SCUBE3

1.20e-051771927b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 TNS3 TBXAS1 CLIC4 CD22 STON2 MEGF10

1.83e-05189192742ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACACB SHROOM4 TNS3 CLIC4 CD22 STON2 MEGF10

1.83e-05189192737ecbd73408d462b47d7e5611f203143e08a2689
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RHOU SHROOM4 DMBT1 CLIC4 CD22 MEGF10 TRIM51G

1.90e-0519019276b101359f397020a21e2bfd15851cb48e71f4502
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

KDM5B TASOR2 USP32 DYNC1H1 FRYL IGF2R PCNX1

2.10e-051931927abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

AP2A2 MPPED2 TBXAS1 NFAM1 TG PCNX1 MUC6

2.10e-0519319275fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P4HA3 FZD4 IQSEC3 ANGPT2 ZNF521 PKHD1L1 STON2

2.10e-051931927bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

P4HA3 SLC27A3 IQSEC3 ANGPT2 ZNF521 PKHD1L1 STON2

2.17e-051941927640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

AP2A2 MPPED2 TBXAS1 NFAM1 TG PCNX1 MUC6

2.17e-051941927ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

PTPN13 NRXN3 ARRDC3 FGG DMBT1 NBPF20 DCBLD2

2.39e-051971927fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERN1 TRBV24-1 TRBV19 TRBV6-5 TRBV6-4 TRBV6-1 TRAV27

2.39e-0519719274bc76958ca12af2dd490d4865de6a92554a14656
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAIP AP2A2 MPPED2 IGLON5 TNS3 TBXAS1 STON2

2.47e-051981927c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PTPN13 NRXN3 ATXN7 ARRDC3 WDR17 CCNJ DSEL

2.55e-051991927121de4e02585de3a3010398387c523bacf8ce546
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR0B1 CACNA1B FAT3 SLURP1 POM121L2 MEGF10

5.76e-0515519268fdda4e3657ac56188ae88ed3caf145f4d9d1567
Diseasecerebral palsy (implicated_via_orthology)

AGAP4 AGAP7P AGAP6

2.55e-05101793DOID:1969 (implicated_via_orthology)
Diseaseintraocular pressure measurement

MYOC GAB2 MAPK8IP3 ADSS2 ANGPT2 TRAV6 KLHL38 MYOF OR4C46 AKAP13 DSEL TRIM51G

7.02e-0550917912EFO_0004695
Diseasephysical activity

SETD1B ARAP2 NLRP8 ZNF521 PCF11

2.03e-04881795EFO_0003940
Diseasecysteine-rich secretory protein LCCL domain-containing 2 measurement

USP32 CRISPLD2

2.18e-0441792EFO_0801512
DiseaseMuscular Atrophy, Spinal, Type II

NAIP DYNC1H1

2.18e-0441792C0393538
DiseaseMuscular atrophy, spinal, infantile chronic form

NAIP DYNC1H1

2.18e-0441792C2931358
Diseaseresponse to non-steroidal anti-inflammatory, drug-induced liver injury

CAMTA1 TBXAS1

2.18e-0441792EFO_0004228, EFO_0005533
DiseaseJuvenile Spinal Muscular Atrophy

NAIP DYNC1H1

2.18e-0441792C0152109
DiseaseHMN (Hereditary Motor Neuropathy) Proximal Type I

NAIP DYNC1H1

2.18e-0441792C0043116
DiseaseIntellectual Disability

OR5M1 MAPK8IP3 SHROOM4 KMT2C DYNC1H1 CACNA1B IQSEC3 RTTN LINS1 SERAC1

4.28e-0444717910C3714756
Diseasestimulant use measurement

HIVEP1 FAM135A PDZRN4

6.43e-04281793EFO_0600076
Diseasepostherpetic neuralgia

CABLES1 NRXN3

1.00e-0381792MONDO_0041052
DiseaseGlaucoma

CPAMD8 MYOC

1.28e-0391792C0017601
DiseaseAlzheimer disease, fasting blood glucose measurement

OR4S1 MADD

1.28e-0391792EFO_0004465, MONDO_0004975
Diseasemembranoproliferative glomerulonephritis (biomarker_via_orthology)

MYOC ANGPT2

1.59e-03101792DOID:2920 (biomarker_via_orthology)
DiseasePR domain zinc finger protein 1 measurement

USP4 MED16

1.94e-03111792EFO_0801904
Diseaseobesity (biomarker_via_orthology)

PDE3A ACACB PPARGC1A FGG GPAM

2.07e-031471795DOID:9970 (biomarker_via_orthology)
Diseaseplatelet component distribution width

SLFN14 GAB2 CABLES1 PTPRH ARRDC3 CAMTA1 HERC1 RTTN CLIC4 AKAP13 DEPDC7 FGD6

2.31e-0375517912EFO_0007984
Diseasekiller cell immunoglobulin-like receptor 2DL4 measurement

SLFN14 KIR2DL4

2.32e-03121792EFO_0008197
Diseaseage at menopause

GAB2 TASOR2 ADSS2 DYNC1H1 PITPNM2 FRYL CCNJ

2.55e-033021797EFO_0004704
DiseaseQRS amplitude, QRS complex

HIVEP1 CLCN6 MPPED2

3.49e-03501793EFO_0005054, EFO_0007742
Diseaseamyotrophic lateral sclerosis, age at onset

NRXN3 ARAP2

3.65e-03151792EFO_0004847, MONDO_0004976
Disease3-hydroxyanthranilic acid measurement

CCPG1 TG

3.65e-03151792EFO_0010447
Diseasecerebellar volume measurement

MCHR2 USP4 PAX3

3.90e-03521793EFO_0020864
Diseasediabetic retinopathy (implicated_via_orthology)

PPARGC1A ANGPT2

4.15e-03161792DOID:8947 (implicated_via_orthology)
Diseasepulse pressure measurement

PDE3A MAST2 PPARGC1A OR4S1 CLCN6 ATXN7 MPPED2 TNS3 TBXAS1 FAT3 FRYL MADD MEGF8 OR4C46 AKAP13 TRIM49B FGD6

4.91e-03139217917EFO_0005763

Protein segments in the cluster

PeptideGeneStartEntry
LSPIYCAFQNDLLTS

UMODL1

1076

Q5DID0
KTNSCLTTTFYGSAP

nan

81

Q75L30
AYQSNTVAACSPFVL

NAIP

871

Q13075
STVRFSQQYSLCSTI

AGAP4

111

Q96P64
SQQYSLCSTIFLDDS

AGAP4

116

Q96P64
FNTNDQSLIYTLLTC

BTNL3

421

Q6UXE8
YQLSISCATSPGFQL

ADGRF3

341

Q8IZF5
LTNAYSRDEFTNTCP

CLIC4

221

Q9Y696
NYSCLFDQISVPASL

CAMTA1

901

Q9Y6Y1
SKSAAQNYTCLPDAT

ANKRD30B

446

Q9BXX2
CNTSFSYLVASAIPS

CDCP1

476

Q9H5V8
TSLQSSTGFQPYCLV

GSDMD

26

P57764
QQGFNYCTSAISSPL

AKAP13

1671

Q12802
DNCRSSSSPYVSNAV

ANGPT2

51

O15123
SYTLQTCPAGFQTSV

CCNJ

311

Q5T5M9
DSSAVSSQAISPYAC

ARAP2

461

Q8WZ64
QSTFLCDFLYQAPSA

ARAP2

891

Q8WZ64
DSSCSLYRFTTIPNQ

DEPDC7

126

Q96QD5
TFSQLETFSVSLCPF

BBS12

146

Q6ZW61
QPSSSSSEKQRFYSC

CACNA1B

2116

Q00975
VLQFLSFNCSSYTPT

CDHR4

36

A6H8M9
SFNCSSYTPTPTLEL

CDHR4

41

A6H8M9
ISFDCLNDSNVPVYS

ARRDC3

11

Q96B67
SQQYSLCSTIFLDDS

AGAP6

116

Q5VW22
TSTQFLNFTPTLICS

AP2A2

746

O94973
SSAYNTAESCRSTPL

PDZRN4

736

Q6ZMN7
LSFVDICYSSNVTPN

OR5M10

66

Q6IEU7
FPSLCQLGKYTTNSS

RARG

201

P13631
PCTSEQNCTSPFSYK

ITGB1

206

P05556
QNCTSPFSYKNVLSL

ITGB1

211

P05556
ALTSNCENYNTVSPS

PARPBP

116

Q9NWS1
QIPSLYCSYETNSNA

P4HA3

316

Q7Z4N8
AQYASNITSVLCQFP

ACACB

1066

O00763
YNSSNCSLSSSENPY

MEGF10

1016

Q96KG7
TYINASTCTVSFQPT

MPPED2

266

Q15777
PQNSSCATLSEYSRQ

MUC6

266

Q6W4X9
TSPILALSCTDTYNT

OR8H2

181

Q8N162
LAFVDLCYTSNATPQ

OR5M11

66

Q96RB7
NLSFLDICYTTSSVP

OR13C6P

66

Q8NH95
NLSFLDICYTTSSVP

OR13C7

66

P0DN81
NLSFLDLCYTTSSIP

OR2J1

66

Q9GZK6
DNSSFTACIPYPQTD

NMBR

191

P28336
NSCVNPFALYLLSES

NMBR

316

P28336
TSVSQIPFYSSDLPC

KMT2C

3446

Q8NEZ4
YLNPAVSDQDCSTAT

LINS1

31

Q8NG48
NSTLTSLCVLSHYPF

MADD

171

Q8WXG6
TCQGLPDSESSFTYT

MAGEC2

126

Q9UBF1
SDLGQLQSSSSYQCP

MAPK8IP3

236

Q9UPT6
LNSAINPLIYCVFSS

NPSR1

321

Q6W5P4
LTQSCPNATSVFVRY

NLRP8

416

Q86W28
GQPNVLCYASTIFSS

SLC2A10

246

O95528
PYDSLPTSQTCFFQL

HERC1

4801

Q15751
ECPFSLTISLNSSNY

GDF3

296

Q9NR23
ISDTCAVSYSNALSP

FAM135A

1051

Q9P2D6
QSPARASVASQSSYC

PCNX1

2116

Q96RV3
FIDACYSSVNTPNLI

OR4C46

66

A6NHA9
SFSTLPTVISTFCFN

OR51I1

76

Q9H343
YCDLPQLFQLSCSST

OR3A1

181

P47881
NLSFLDLCYSTVTTP

OR4Q2

66

P0C623
LSQLSFADICYPSTT

OR4S1

61

Q8NGB4
NLSFLDICYVSSTAP

OR5A2

66

Q8NGI9
NPVTSLSENYTCSDS

PDE3A

396

Q14432
PVFGTNIYADTSSIC

CRISPLD2

426

Q9H0B8
SVLALQNSSFIYPSC

DDIAS

11

Q8IXT1
GDTPSLQEYQCSSST

FRYL

2461

O94915
LQEYQCSSSTPSLNL

FRYL

2466

O94915
NSPLNITGSNSSYEC

HHLA2

196

Q9UM44
YLCYDLSQNPIQSSS

NRXN3

266

Q9Y4C0
FIEASSENPCSLYSS

KBTBD2

271

Q8IY47
DSSTPCTLSYVLAFD

MEGF8

1331

Q7Z7M0
RCQYTFSVASPNESS

MYOC

46

Q99972
ECAVNTFLTENSPYS

KDM5B

1071

Q9UGL1
LCYSNQPVSESQSSS

PITPNM2

571

Q9BZ72
PCIFSVSYCSSNIIN

OR8J3

161

Q8NGG0
EPLLSQALSCYTSSS

IQSEC3

1111

Q9UPP2
ITSLSYANSCLNPFL

NPBWR2

301

P48146
TNSVPTSQCGVSYLA

ATXN7

581

O15265
NCLSFNPYSEFILAT

RBBP7

276

Q16576
RTNTAYQCFSILPQS

MED14

896

O60244
SCLPVYTATSDTQDS

MED16

671

Q9Y2X0
SSLLPATAYNCSVTS

PTPRO

781

Q16827
QSTIPSNPDSSSAYC

PAX3

341

P23760
AFYDSCVNSVSDPSI

PARP12

646

Q9H0J9
AYIQPICIESSTFNF

PRSS41

161

Q7RTY9
QDELTFTCTSINGYP

ICOSLG

151

O75144
STLYCVPTSTNQAQA

NR0B1

211

P51843
PANTQLSYNECSGLS

PPARGC1A

151

Q9UBK2
DGTQSYSLFNVSPSC

PPARGC1A

526

Q9UBK2
YSLFNVSPSCSSFNS

PPARGC1A

531

Q9UBK2
DYQNTSSFDCTPSPS

PCF11

1481

O94913
NVTLSCSSQSSFDIY

KIR2DL4

141

Q99706
CTNTTAASTYLNNPY

CTSA

331

P10619
DQTSECFSSPSYLRI

ITGB8

671

P26012
SICLSYASSSINPFL

MCHR2

291

Q969V1
QNTDSPSYPEISFSC

COMMD3

156

Q9UBI1
PTTCGIADFLSTYQT

FGG

46

P02679
TFTPLIQYGCSSQLQ

FZD4

81

Q9ULV1
SSQYTFCQPETVFSS

CCPG1

141

Q9ULG6
VNSSIKTFFCPNDTY

CLCN6

421

P51797
QSLEFNSPADNYTVC

IGLON5

31

A6NGN9
TVLQASPQDTGNYSC

IGSF3

1066

O75054
AFSRPTSQNYCSLEQ

CABLES1

251

Q8TDN4
SAFADSLCPSTSLLY

ERN1

141

O75460
NDQNLCIPASSSFVY

GAN

506

Q9H2C0
CALEQRLPASSSSTY

CPAMD8

1756

Q8IZJ3
EESTNQTFISCAPYP

GRPR

186

P30550
IPFANCSYPSSTAVQ

C4orf17

76

Q53FE4
AYTPCFQSDSRSNLD

FAT3

4236

Q8TDW7
SQQYSLCSTIFLDDS

AGAP7P

116

Q5VUJ5
KPTGSICASFLTQSY

FAM169A

161

Q9Y6X4
QFSSCSPRFNKVYSS

MAST2

841

Q6P0Q8
TYCPTLQDQSSISGS

ITIH6

226

Q6UXX5
TVSQQYLPLSTACSS

DYNC1H1

3796

Q14204
PSNQVYSTDLCSPST

KRTAP13-1

31

Q8IUC0
NPSTYNFDATCLLNS

AHCTF1

471

Q8WYP5
RTDSCSSAQAQYDTP

DCBLD2

721

Q96PD2
RESSNFDSIYICPST

HDAC6

561

Q9UBN7
TLFVDTCVASPYSND

DMBT1

2296

Q9UGM3
TCVASPYSNDFTSLT

DMBT1

2301

Q9UGM3
NSSPSSITTYETCQT

SCUBE3

866

Q8IX30
NPCFASSNIYSDSER

CFAP47

1736

Q6ZTR5
YINVSSCRFIDSSNP

DSEL

686

Q8IZU8
DTVTLSCNYNSSNPS

CD22

436

P20273
SCSELSLYQPLQNSS

PTPN13

936

Q12923
FITSLSYANSCLNPF

NPBWR1

291

P48145
TVLTYLTNFSASCPI

OR2B2

326

Q9GZK3
LSFLDICYTSSSVPS

OR13C3

96

Q8NGS6
PLCSTFSDQSAYVSA

NXF2

331

Q9GZY0
AYLCPSSSSSNSVKE

OR1P1

271

Q8NH06
AIFNSYPDSSQSRFC

RNF139

36

Q8WU17
NDTCLSVATFLPYSS

RPGR

381

Q92834
FNSSSSQYCRPISTQ

GAB2

556

Q9UQC2
IANEIYLNFESSTPC

IGF2R

1736

P11717
CYEVFSLSQSSQRPN

PLAC1

146

Q9HBJ0
TCPALYTASLQFLSV

RTTN

1786

Q86VV8
FSSLTTCDPSNIYDL

GTF2H2C;

171

Q6P1K8
CIQYFTSLALSESSQ

SERAC1

226

Q96JX3
NQSSLIYTIPNCSFS

TRIM49

426

P0CI25
TQSAPPSLVTDYNSC

SLFN14

351

P0C7P3
PSLVTDYNSCLISSA

SLFN14

356

P0C7P3
ASAFCTPSYFTLNSQ

SLC38A3

271

Q99624
NLTSDASVYCFEPVS

TCAF1

326

Q9Y4C2
YSTPSSCLELTDSCQ

NBPF20

4661

P0DPF2
SSDSSLFKTQCIPYS

TAF1D

26

Q9H5J8
LSFVDICYSSNVTPN

OR5M1

66

Q8NGP8
FCNTCSSNELALPSY

RUFY1

671

Q96T51
LANTAISFSCRITYP

NFAM1

56

Q8NET5
LSNEGTISLPCQTFY

GPAM

626

Q9HCL2
NSTTSTFCGTPEYLA

SGK1

251

O00141
PQYFSSETSGSCALN

SHROOM4

1161

Q9ULL8
YPFNQSPVVTRSCSS

SLURP1

61

P55000
SLFSCFPNSATLATT

SLC26A10

326

Q8NG04
PFSQDTAYSSCRLDT

SETD1B

251

Q9UPS6
CTQSTNRSLEDSPYT

WDR17

1216

Q8IZU2
IDFGTYPFVTSSNCT

ADSS2

261

P30520
STPSFQQAFASSCTI

TNS3

916

Q68CZ2
TPCYNQTLSFTVLTC

MRGPRX4

21

Q96LA9
AVGNTYSVPSTCDTF

POM121L2

651

Q96KW2
SPSFGCSYTDLQLIN

STON2

161

Q8WXE9
FSLPSQTCLYVHNIT

STXBP5L

961

Q9Y2K9
LYPSCSFIQNLVSAS

BIRC2

106

Q13490
STCPNETVSLTTYFS

USP53

1026

Q70EK8
LCFSVVSPSSFQNVS

RHOU

126

Q7L0Q8
SFATYLLATNPDCQE

TBXAS1

351

P24557
TSFQLLSASACPEYN

TMF1

291

P82094
SLAYFCQADSPRTSV

TXNDC16

46

Q9P2K2
TLQCNYTVSPFSNLR

TRAV10

41

A0A0B4J240
ALQCLSNTAPLTDYF

USP4

316

Q13107
PLSLSQSVCLFYSIS

LINC00052

31

Q96N35
PQSITDTCLYIFTSG

SLC27A3

276

Q5K4L6
FSSLTTCDPSNIYDL

GTF2H2

171

Q13888
PNSFYNLCLTSLSSQ

UFSP1

121

Q6NVU6
DQSSLIYTIPNCSFS

TRIM51

426

Q9BSJ1
NQSSLIYTIPNCSFS

TRIM49C

426

P0CI26
SNCVVYPSSSQDSEN

VSIR

176

Q9H7M9
SCSYCTNSPIFNSVL

ZNF521

561

Q96K83
SSSQAPYKSVTSLCA

FGD6

731

Q6ZV73
VPLFSTQLCNSSCVY

TMPRSS5

366

Q9H3S3
SLESAIPNQTALYFC

TRBV24-1

96

A0A075B6N3
AFSYNCLQTPIITDF

PKHD1L1

1231

Q86WI1
LLFEVSSCFSPSISN

PKHD1L1

1556

Q86WI1
RLESAAPSQTSVYFC

TRBV6-1

96

A0A0K0K1D8
SIECSNFLTSYSPFS

TXNDC11

516

Q6PKC3
DRSSLIYTIPNCSFS

TRIM51G

426

A0A3B3IT33
QEFYSTSCLSPCENN

ZMYM5

311

Q9UJ78
KCPSESLTQLNSYFS

TASOR2

251

Q5VWN6
NQSSLIYTIPNCSFS

TRIM49B

426

A6NDI0
SPLLGNVCFSSSQYS

EFTUD2

301

Q15029
TYSPERGLQFLTNTC

SOHLH2

301

Q9NX45
DYSSLINQASNFSCP

UBR2

1606

Q8IWV8
NLTVYCNSSSVFSSL

TRAV27

36

A0A087WT01
TALQFTYPLFTTNAC

TCFL5

251

Q9UL49
DVASSTQSLCASTYP

PTPRH

651

Q9HD43
TSTSPGVSEDCLYLN

TG

2271

P01266
TLASAVPSQTSVYFC

TRBV6-4

96

A0A1B0GX49
KTATLTCNYTNYSPA

TRAV6

56

A0A075B6T7
ITASQPADSATYLCA

TRAV6

116

A0A075B6T7
TVTSAQKNPTAFYLC

TRBV19

96

A0A075B6N1
QSSVPAYCFATLTSL

HIVEP1

1641

P15822
SYDEVVNQSSPSNCT

TIA1

201

P31483
RLESAAPSQTSVYFC

TRBV6-9

96

A0A0J9YX75
CVSNTQPLTQYFISG

USP32

751

Q8NFA0
RLLSAAPSQTSVYFC

TRBV6-5

96

A0A0K0K1A5
LFSELSACLYSPSSQ

TTI1

96

O43156
AFTTCLYITLSQASP

TAS2R4

141

Q9NYW5
TQPCTPSSSDYSDLQ

VASP

331

P50552
ISPSFCYNLETNSLN

KLF6

91

Q99612
EACSSYLQSQLAPSN

KLHL38

121

Q2WGJ6
PDEDNISFCSQTTSY

KIAA1522

101

Q9P206
DPRIYSCTFAQSVSS

MTNR1A

171

P48039
FDTTCKPLASTTQYS

MYOF

606

Q9NZM1