Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction5-diphosphoinositol pentakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

1.39e-052752GO:0033857
GeneOntologyMolecularFunctioninositol hexakisphosphate 3-kinase activity

PPIP5K1 PPIP5K2

8.31e-054752GO:0052724
GeneOntologyMolecularFunctioninositol hexakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

8.31e-054752GO:0052723
GeneOntologyMolecularFunctioninositol hexakisphosphate 5-kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000832
GeneOntologyMolecularFunctiondiphosphoinositol pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000829
GeneOntologyMolecularFunctioninositol hexakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000828
GeneOntologyMolecularFunctioninositol-1,3,4,5,6-pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000827
GeneOntologyMolecularFunctionphosphotransferase activity, phosphate group as acceptor

MAGI3 PPIP5K1 PPIP5K2

4.90e-0441753GO:0016776
GeneOntologyMolecularFunctioninositol phosphate kinase activity

PPIP5K1 PPIP5K2

7.49e-0411752GO:0180030
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

AKAP6 CUL5 GRIP1 KMT2C RUVBL1 MED9 STEEP1 NCOA7 NBN PARP9 CHD4 DGCR8

1.22e-0311607512GO:0030674
GeneOntologyCellularComponentsite of DNA damage

CUL5 ELOA HUS1 NBN PARP9 CHD4 DGCR8

6.68e-07137767GO:0090734
GeneOntologyCellularComponentspine synapse

GRIP1 GRIA2

1.30e-052762GO:0106033
GeneOntologyCellularComponentdendritic spine neck

GRIP1 GRIA2

4.62e-049762GO:0044326
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

AKAP6 RYR1

5.76e-0410762GO:0014701
DomainIRO

IRX3 IRX1 IRX4

1.34e-066773SM00548
DomainIroquois_homeo

IRX3 IRX1 IRX4

1.34e-066773IPR003893
DomainHomeobox_KN

IRX3 IRX1 IRX4

4.39e-0517773PF05920
DomainHomeobox_KN_domain

IRX3 IRX1 IRX4

4.39e-0517773IPR008422
DomainHomez_dom

ZHX3 ZHX1

5.02e-053772IPR024578
DomainHomez

ZHX3 ZHX1

5.02e-053772PF11569
DomainAcid_Pase_AS

PPIP5K1 PPIP5K2

2.49e-046772IPR033379
DomainHIS_ACID_PHOSPHAT_2

PPIP5K1 PPIP5K2

3.48e-047772PS00778
DomainHIS_ACID_PHOSPHAT_1

PPIP5K1 PPIP5K2

3.48e-047772PS00616
DomainHis_Pase_clade-2

PPIP5K1 PPIP5K2

4.62e-048772IPR000560
DomainHis_Phos_2

PPIP5K1 PPIP5K2

4.62e-048772PF00328
Domain-

ZHX3 IRX3 IRX1 TTF1 ZHX1 IRX4

1.11e-032837761.10.10.60
DomainHomeodomain-like

ZHX3 IRX3 IRX1 TTF1 ZHX1 IRX4

2.48e-03332776IPR009057
DomainPDZ

GRIP1 AHNAK MAGI3 RGS3

2.75e-03141774PF00595
DomainHomeobox

ZHX3 IRX3 IRX1 ZHX1 IRX4

2.81e-03234775PF00046
DomainHOMEOBOX_1

ZHX3 IRX3 IRX1 ZHX1 IRX4

2.91e-03236775PS00027
DomainHOX

ZHX3 IRX3 IRX1 ZHX1 IRX4

2.97e-03237775SM00389
DomainHis_PPase_superfam

PPIP5K1 PPIP5K2

3.04e-0320772IPR029033
Domain-

PPIP5K1 PPIP5K2

3.04e-03207723.40.50.1240
DomainHOMEOBOX_2

ZHX3 IRX3 IRX1 ZHX1 IRX4

3.08e-03239775PS50071
DomainHomeobox_dom

ZHX3 IRX3 IRX1 ZHX1 IRX4

3.08e-03239775IPR001356
DomainPDZ

GRIP1 AHNAK MAGI3 RGS3

3.27e-03148774SM00228
Domain-

GRIP1 AHNAK MAGI3 RGS3

3.43e-031507742.30.42.10
DomainPDZ

GRIP1 AHNAK MAGI3 RGS3

3.52e-03151774PS50106
DomainPDZ

GRIP1 AHNAK MAGI3 RGS3

3.60e-03152774IPR001478
DomainGRAM

GRAMD2A NCOA7

3.67e-0322772PF02893
DomainGRAM

GRAMD2A NCOA7

3.67e-0322772IPR004182
DomainPHD

KMT2C BAZ1B CHD4

3.68e-0375773PF00628
DomainZnf_PHD-finger

KMT2C BAZ1B CHD4

4.26e-0379773IPR019787
DomainDHHC

KMT2C ZDHHC23

4.73e-0325772PS50216
DomainZnf_DHHC_palmitoyltrfase

KMT2C ZDHHC23

4.73e-0325772IPR001594
DomainPHD

KMT2C BAZ1B CHD4

5.93e-0389773SM00249
DomainZnf_PHD

KMT2C BAZ1B CHD4

6.31e-0391773IPR001965
DomainZF_PHD_2

KMT2C BAZ1B CHD4

7.11e-0395773PS50016
DomainZF_PHD_1

KMT2C BAZ1B CHD4

7.31e-0396773PS01359
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZHX3 ELOA RUVBL1 AHNAK STEEP1 GNL2 BAZ1B NBN RPRD2 CHD4 DGCR8 CWC25 L3MBTL3 SF3B2

2.49e-08954781436373674
Pubmed

Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

IRX3 IRX1 IRX4

2.16e-07678320408909
Pubmed

Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression.

IRX3 IRX1 IRX4

2.16e-07678336773339
Pubmed

Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

IRX3 IRX1 IRX4

2.16e-07678311042145
Pubmed

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

IRX3 IRX1 IRX4

2.16e-07678310370142
Pubmed

The prepattern transcription factor Irx3 directs nephron segment identity.

IRX3 IRX1 IRX4

3.77e-07778317875669
Pubmed

Nucleolar proteome dynamics.

ELOA RUVBL1 GNL2 BAZ1B EXOSC8 CHD4 SF3B2 DYNC1H1 CCNB1

4.30e-0741978915635413
Pubmed

Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol.

IRX3 IRX1 IRX4

6.03e-07878311118473
Pubmed

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.

IRX3 IRX1 IRX4

9.03e-07978314585979
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

IRX3 IRX1 IRX4

9.03e-07978311520674
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

ZHX3 ELOA STEEP1 GNL2 RPRD2 CHD4 L3MBTL3 SF3B2

9.72e-0733978830415952
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KMT2C RUVBL1 POLR3E MED9 AHNAK STEEP1 BAZ1B NBN RPRD2 CHD4 TTF1 L3MBTL3 ESCO1 SF3B2

1.00e-061294781430804502
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

ELOA STEEP1 GNL2 BAZ1B CHD4 TTF1

1.07e-0614878632538781
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZHX3 ELOA RUVBL1 AHNAK STEEP1 GNL2 BAZ1B NCOA7 NBN RPRD2 CHD4 SF3B2

1.12e-06934781233916271
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

IRX3 IRX1 IRX4

1.77e-061178310926765
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

ZHX3 RUVBL1 MYO1D BAIAP2L1 STEEP1 RPRD2 CHD4 SF3B2 DYNC1H1

2.04e-0650678930890647
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

AHNAK STEEP1 GNL2 NBN RPRD2 CHD4 SF3B2

2.66e-0627178732433965
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

ELOA RUVBL1 STEEP1 GNL2 BAZ1B RPRD2 SF3B2

3.54e-0628378730585729
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

RUVBL1 AHNAK BAZ1B NBN CHD4

4.23e-0610678519394292
Pubmed

Imaging-based assays for investigating functions of the RNA polymerase II elongation factor Elongin and the Elongin ubiquitin ligase.

CUL5 ELOA

4.97e-06278230794906
Pubmed

Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.

PPIP5K1 PPIP5K2

4.97e-06278218981179
Pubmed

Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.

PPIP5K1 PPIP5K2

4.97e-06278217702752
Pubmed

Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor.

GRIP1 GRIA2

4.97e-06278210985351
Pubmed

The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.

PPIP5K1 PPIP5K2

4.97e-06278228126903
Pubmed

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

PPIP5K1 PPIP5K2

4.97e-06278217690096
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

FSIP2 ZHX3 ELOA STEEP1 GNL2 BAZ1B EXOSC8 CHD4 ZHX1

8.97e-0660878936089195
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

ELOA AHNAK RPRD2 CHD4 SF3B2

1.15e-0513078535545047
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

AHNAK NBN EXOSC8 RPRD2 PARP9 CHD4 SF3B2

1.17e-0534078724332808
Pubmed

PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.

PPIP5K1 PPIP5K2

1.49e-05378231852976
Pubmed

PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.

GRIP1 GRIA2

1.49e-05378222915106
Pubmed

GRIP1 regulates synaptic plasticity and learning and memory.

GRIP1 GRIA2

1.49e-05378232948689
Pubmed

The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior.

GRIP1 GRIA2

1.49e-05378221496646
Pubmed

PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression.

GRIP1 GRIA2

1.49e-05378221847098
Pubmed

GRIP1 is required for homeostatic regulation of AMPAR trafficking.

GRIP1 GRIA2

1.49e-05378226216979
Pubmed

Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma.

ZHX3 ZHX1

1.49e-05378228152006
Pubmed

Kif3a deletion prevents primary cilia assembly on oligodendrocyte progenitor cells, reduces oligodendrogenesis and impairs fine motor function.

PDGFRA KIF3A

1.49e-05378233368703
Pubmed

Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system.

IRX3 IRX1

1.49e-0537829486539
Pubmed

mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope.

AKAP6 RYR1

1.49e-05378211590243
Pubmed

The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia.

IRX3 IRX1

1.49e-05378235328612
Pubmed

Glial progenitor cells in normal and pathological states.

PDGFRA CXCL2

1.49e-0537829884514
Pubmed

Transmembrane and ubiquitin-like domain-containing protein 1 (Tmub1/HOPS) facilitates surface expression of GluR2-containing AMPA receptors.

GRIP1 GRIA2

1.49e-05378218665261
Pubmed

Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism.

GRIP1 GRIA2

1.49e-05378221383172
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

GRIP1 STXBP3 RUVBL1 MYO1D BAIAP2L1 HUS1 MAGI3 NBN PPIP5K2 DYNC1H1

2.09e-05853781028718761
Pubmed

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.

STEEP1 BAZ1B CHD4 SF3B2

2.14e-057278431248990
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

ZHX3 RUVBL1 BAIAP2L1 MED9 BAZ1B CHD4 MSI1 DYNC1H1

2.64e-0553378830554943
Pubmed

Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.

IRX3 IRX1 IRX4

2.72e-052678311238910
Pubmed

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.

CUL5 ELOA

2.97e-05478228292928
Pubmed

The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling.

GRIP1 GRIA2

2.97e-05478212458226
Pubmed

Evidence that GRIP, a PDZ-domain protein which is expressed in the embryonic forebrain, co-activates transcription with DLX homeodomain proteins.

GRIP1 GRIA2

2.97e-05478211675124
Pubmed

GRIP1 interlinks N-cadherin and AMPA receptors at vesicles to promote combined cargo transport into dendrites.

GRIP1 GRIA2

2.97e-05478224639525
Pubmed

Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.

HUS1 NBN

2.97e-05478212529385
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

FSIP2 ZHX3 RUVBL1 BAIAP2L1 AHNAK RPRD2 SF3B2

3.26e-0539978735987950
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2C RUVBL1 AHNAK STEEP1 BAZ1B NBN RPRD2 DYNC1H1

3.26e-0554978838280479
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

KMT2C CHD4 SF3B2

4.22e-053078317403666
Pubmed

Iroquois genes influence proximo-distal morphogenesis during rat lung development.

IRX3 IRX1

4.94e-05578216299054
Pubmed

ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome.

ZHX3 ZHX1

4.94e-05578217056598
Pubmed

Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses.

CUL5 ELOA

4.94e-05578225878247
Pubmed

Expression of two novel mouse Iroquois homeobox genes during neurogenesis.

IRX3 IRX1

4.94e-05578210704856
Pubmed

Expression of Irx6 during mouse morphogenesis.

IRX3 IRX4

4.94e-05578211335133
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ELOA RUVBL1 GNL2 BAZ1B EXOSC8 CHD4 DGCR8 TTF1 L3MBTL3

5.10e-0575978935915203
Pubmed

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

ELOA GNL2 BAZ1B DYNC1H1

5.17e-059078435654790
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

HUS1 MED9 NBN EXOSC8 RPRD2 DGCR8 ZHX1

7.23e-0545378729656893
Pubmed

Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation.

PDGFRA IRX3

7.40e-05678211830569
Pubmed

Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5.

PDGFRA CXCL2

7.40e-0567821647018
Pubmed

Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment.

PIK3CG CXCL2

7.40e-05678220107187
Pubmed

The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell death.

GRIP1 GRIA2

7.40e-05678224749734
Pubmed

Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube.

PDGFRA IRX3

7.40e-05678216469306
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

AKAP6 PPIP5K1 DYNC1H1 ZNF518A

9.08e-051047849205841
Pubmed

PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils.

PIK3CG CXCL2

1.04e-04778218536720
Pubmed

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

GRIP1 GRIA2

1.04e-04778217093100
Pubmed

Ankyrin repeat and suppressors of cytokine signaling box protein asb-9 targets creatine kinase B for degradation.

CUL5 ELOA

1.04e-04778217148442
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

ELOA RUVBL1 GNL2 EXOSC8 CHD4 DGCR8 DYNC1H1

1.08e-0448378736912080
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYO1D AHNAK GNL2 BAZ1B CHD4 TTF1 SF3B2 DYNC1H1

1.09e-0465378822586326
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ELOA COL17A1 RUVBL1 MYO1D BAIAP2L1 AHNAK GNL2 BAZ1B EXOSC8 SF3B2 DYNC1H1

1.11e-041257781136526897
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

COL17A1 RUVBL1 MYO1D STEEP1 CHD4 SF3B2 DYNC1H1

1.19e-0449178736273042
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

CUL5 ZHX3 GNL2 BAZ1B NBN SF3B2

1.21e-0434178632971831
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GRIP1 FSIP2 BAIAP2L1 PDGFRA AHNAK NCOA7 MAGI3 PPIP5K2 ARHGAP19

1.33e-0486178936931259
Pubmed

Identification of a novel mouse Iroquois homeobox gene, Irx5, and chromosomal localisation of all members of the mouse Iroquois gene family.

IRX3 IRX1

1.38e-04878210822268
Pubmed

Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel.

PDGFRA CXCL2

1.38e-0487821372902
Pubmed

Myosin Va, a Novel Interaction Partner of STXBP1, Is Required to Transport Syntaxin1A to the Plasma Membrane.

MYO1D GRIA2

1.38e-04878237315734
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AKAP6 ZHX3 KMT2C RPRD2 ZNF518A

1.56e-0422578512168954
Pubmed

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

RUVBL1 STEEP1 GNL2 BAZ1B

1.63e-0412178422412018
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

FSIP2 RUVBL1 CCDC168 TTF1

1.74e-0412378426912792
Pubmed

Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3.

ZHX3 ZHX1

1.77e-04978212659632
Pubmed

Chromosome mapping of the rod photoreceptor cGMP phosphodiesterase beta-subunit gene in mouse and human: tight linkage to the Huntington disease region (4p16.3).

PDGFRA CXCL2

1.77e-0497821315306
Pubmed

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.

L3MBTL3 CCNB1

1.77e-04978222157815
Pubmed

Role and regulation of PDGFRα signaling in liver development and regeneration.

PDGFRA PIK3CG

1.77e-04978223529017
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

RUVBL1 MAGI3 CHD4 DYNC1H1

2.02e-0412878423858473
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

GRIP1 RUVBL1 MYO1D STEEP1 GNL2 EXOSC8 SF3B2 KIF3A

2.19e-0472378834133714
Pubmed

Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification.

IRX3 IRX4

2.21e-041078227052172
Pubmed

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.

PDGFRA FAM136A

2.21e-041078219515974
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

ELOA RUVBL1 AHNAK GNL2 CHD4 MSI1 ARHGAP19

2.31e-0454778737267103
Pubmed

Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.

RUVBL1 CHD4 CCNB1

2.34e-045378336841324
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ELOA STXBP3 GNL2 NBN RPRD2 PPIP5K2 CWC25 SF3B2

2.40e-0473378834672954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

KMT2C MAGEB4 AHNAK MAGI3 SLC28A3 ESCO1 DYNC1H1 RYR1

2.46e-0473678829676528
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

GRIP1 FSIP2 RUVBL1 AHNAK PLPPR3 DGCR8 DYNC1H1

2.60e-0455878735063084
Pubmed

Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord.

PDGFRA IRX3

2.70e-041178217344230
Pubmed

The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins.

BAZ1B NBN

2.70e-041178224800743
Pubmed

Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.

CHD4 CWC25 TTF1

2.76e-045678326919559
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

RUVBL1 AHNAK STEEP1 SF3B2 DYNC1H1

2.83e-0425678533397691
InteractionH2BC21 interactions

CUL5 RUVBL1 MED9 AHNAK BAZ1B NBN MTBP RPRD2 PARP9 CHD4 TTF1 L3MBTL3 ESCO1 DYNC1H1 VWA5B1

4.93e-086967715int:H2BC21
InteractionH3C1 interactions

GRIP1 ELOA KMT2C WDR87 AHNAK STEEP1 GNL2 BAZ1B NBN CHD4 L3MBTL3 ESCO1 SF3B2 DYNC1H1

7.00e-069017714int:H3C1
InteractionSMC5 interactions

ZHX3 ELOA RUVBL1 AHNAK STEEP1 GNL2 BAZ1B NBN RPRD2 CHD4 DGCR8 CWC25 L3MBTL3 SF3B2

2.26e-0510007714int:SMC5
InteractionH3-3A interactions

ZHX3 ELOA KMT2C RUVBL1 PDGFRA STEEP1 GNL2 BAZ1B EXOSC8 CHD4 ZHX1 SF3B2

2.55e-057497712int:H3-3A
Cytoband5p15.3

IRX1 IRX4

1.27e-04107825p15.3
Cytoband10q24.1

ZNF518A ARHGAP19

6.44e-042278210q24.1
Cytoband3q21

RUVBL1 PARP9

7.68e-04247823q21
Cytoband1p36.12

PLA2G2D VWA5B1

2.03e-03397821p36.12
GeneFamilyTALE class homeoboxes and pseudogenes

IRX3 IRX1 IRX4

6.96e-0526563526
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZHX3 ZHX1

9.64e-0415562529
GeneFamilyPDZ domain containing

GRIP1 AHNAK MAGI3 RGS3

1.26e-031525641220
GeneFamilyPHD finger proteins

KMT2C BAZ1B CHD4

2.73e-039056388
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A MYO1D BAIAP2L1 MAGI3 IRX1

9.24e-071867863aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A BAIAP2L1 MAGI3 IRX3 IRX1

9.53e-07187786ff26a533d310126521efe1d05cf8b9d32e524550
ToppCellfacs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1D HUS1 FAM136A NCOA7 ZHX1

1.03e-051647851d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1D HUS1 FAM136A NCOA7 ZHX1

1.03e-05164785bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A BAIAP2L1 MAGI3 IRX1

1.57e-0517978504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A MYO1D BAIAP2L1 MAGI3

1.66e-05181785b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A BAIAP2L1 IRX3 IRX1

1.75e-05183785274483009b309289e4cb84beedf6806430db6ff6
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A BAIAP2L1 IRX3 IRX1

1.84e-051857853bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A BAIAP2L1 MAGI3 IRX1

1.84e-05185785c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

TGFBR3 PDGFRA SERPING1 IRX3 RGS3

1.89e-051867856ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GRIP1 TACR3 IRX3 IRX1 CCNB1

2.15e-0519178539220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellPND03-Epithelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A BAIAP2L1 MAGI3 IRX3 IRX1

2.20e-05192785d8c23693f690d4d568585537bbfedda05d505b3d
ToppCellEpithelial|World / shred on cell class and cell subclass (v4)

GRAMD2A BAIAP2L1 MAGI3 IRX3 IRX1

2.20e-0519278513a3553d9a7c78535679d23d454c63fd08f7d218
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFBR3 PDGFRA PTPRS SERPING1 CXCL2

2.37e-05195785fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFBR3 PDGFRA PTPRS SERPING1 CXCL2

2.49e-05197785ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell5'-Adult-Appendix-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFBR3 PDGFRA PTPRS SERPING1 CXCL2

2.49e-05197785b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RUVBL1 PDGFRA PTPRS GRIA2 CCNB1

2.55e-05198785039b67ddd0ac529453a364552abca04e67d8417c
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

KMT2C AHNAK SERPING1 PARP9 DYNC1H1

2.55e-0519878561ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RUVBL1 PDGFRA PTPRS GRIA2 CCNB1

2.55e-05198785a07307ecc3d86fbcaf7369b7fce60334b7e2dc8f
ToppCellNasal_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

IL32 SERPING1 NCOA7 SLC28A3 CXCL2

2.61e-05199785aa6f1390283617c7f9aaf91d379024832ea24a9e
ToppCellNasal_Brush-Epithelial-Goblet_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

IL32 SERPING1 NCOA7 SLC28A3 CXCL2

2.61e-051997852ac716f887687b5109fb9feced75d5c62646a268
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KMT2C AHNAK SERPING1 PARP9 DYNC1H1

2.68e-0520078512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellSepsis-Leuk-UTI|Sepsis / Disease, condition lineage and cell class

GRIP1 IL32 PTPRS LRRC69 SERPING1

2.68e-052007857d92b24c0c888dd46e40b7e3c6c2645c3604f132
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A MYO1D BAIAP2L1 MAGI3

8.04e-051307846434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRIP1 TDRD15 ZHX1 VWA5B1

1.07e-04140784e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCellEpithelial-B_(AT1-AT2-progenitors)|World / shred on cell class and cell subclass (v4)

GRAMD2A MAGI3 IRX3 IRX1

1.26e-041467844511916904c1fac252cb68e871b782207f8137b3
ToppCellfacs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS AHNAK LRRC69 TACR3

1.29e-041477849d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCellfacs-Marrow-B-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRS AHNAK LRRC69 TACR3

1.29e-0414778438552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

ELOA CHD4 CCDC168 ZNF518A

1.36e-04149784768877bade04ca0321593b8470b5011ad8270431
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDGFRA SERPING1 DGCR8 MSI1

1.55e-0415478444d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

TGFBR3 TACR3 IRX3 IRX4

1.55e-04154784df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G2D AHNAK TACR3 RYR1

1.62e-041567842ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

PDE6A PTPRS RYR1 CCNB1

1.83e-041617847a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

TGFBR3 IL32 PIK3CG AHNAK

1.97e-0416478492fb94492fc2b683e9d50a9db6f01d23c194b0e4
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TGFBR3 IL32 AHNAK IRX1

2.21e-0416978417568e7aacfdcd96c469bae57d5ffad04954e9bd
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

TGFBR3 PDGFRA SERPING1 CXCL2

2.21e-0416978484b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL32 COL17A1 AHNAK CXCL2

2.31e-041717840de81d12a8000f2c59cdb214e67dc526d18098fe
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL32 COL17A1 AHNAK CXCL2

2.31e-041717840597339618fb4d416d55c538eceb353218a55002
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 PTPRS AHNAK RYR1

2.41e-04173784ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A MAGI3 IRX3 IRX1

2.41e-0417378445808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL17A1 PTPRS AHNAK RYR1

2.41e-0417378419a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A MAGI3 IRX3 IRX1

2.41e-041737847fa9dbcb258c3ab974490063951620e2def03db1
ToppCellP07-Epithelial|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

2.41e-041737848b10087a917b825809d35a2b2b349c73a2782472
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO1D ZDHHC23 PIK3CG MAGI3

2.47e-04174784bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STXBP3 PLA2G2D CXCL2 ARHGAP19

2.47e-0417478433e5903adb746f693433bdca11a75c508bbf50c0
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

2.47e-04174784d0e3d15731de6c19c232e3aa492c39d8151cf4ed
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STXBP3 PLA2G2D CXCL2 ARHGAP19

2.47e-04174784ca0c2f42544092848541863c4a47b334e6828b8a
ToppCellP07-Epithelial-alveolar_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

2.47e-041747842739de68e0266054694f99807cfb1f07b6bbb371
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 ZHX3 AHNAK ESCO1

2.58e-04176784749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellIIH-CD8-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

MED9 STEEP1 PARP9 RGS3

2.63e-04177784fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCellP15-Epithelial|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

2.75e-04179784869d3d203e2cb88636e2f0c4476c72571ae3b5ca
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRAMD2A MAGI3 IRX3 IRX1

2.75e-0417978488dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRAMD2A MAGI3 IRX3 IRX1

2.75e-04179784daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIP1 NCOA7 MAGI3 VWA5B1

2.75e-04179784e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 TRPM4 MAGI3 DGCR8

2.81e-0418078412f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 TRPM4 MAGI3 DGCR8

2.81e-041807841bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 SLC28A3 IRX3 IRX1

2.81e-04180784b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFBR3 TRPM4 MAGI3 DGCR8

2.81e-041807842a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCellP03-Epithelial-alveolar_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

2.87e-04181784c3dbf8850d3812fbb770798f4cf38908db8bb92b
ToppCellP15-Epithelial-alveolar_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

2.87e-041817847033be0ba90556f7e5f7c0d4a9f7644afcb22c9b
ToppCellP03-Epithelial|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

2.87e-04181784de0466072f5b2ab8db3d9bab31e3205d1ff7cfb7
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

GRIP1 NCOA7 MAGI3 CXCL2

2.87e-04181784c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

2.93e-04182784a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A AHNAK MAGI3 IRX3

2.93e-04182784573771130247e869e4e58f22d4a1cb31989635cf
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

2.93e-04182784cc79e0cc21e2fdc4ef77f052818d27b9f707aec1
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAIAP2L1 SLC28A3 IRX3 IRX1

2.93e-041827841e2149b222a3e9f64841aed45288a6f29394e7b0
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A AHNAK MAGI3 IRX3

2.93e-041827846cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCelllymphoid-T_cell-CD8+_Effector_T_cell|lymphoid / Lineage, cell class and subclass

TGFBR3 IL32 EVC2 RYR1

2.93e-04182784d4ef4a7c0f5dc044eb5cc6c0bcf539c88b1b4fef
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

KMT2C NCOA7 PARP9 CXCL2

2.99e-041837848f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

GRIP1 GRAMD2A MYO1D MAGI3

2.99e-04183784942530449e9c6583705eeb8f6f12621daea57252
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

2.99e-0418378406ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

BAIAP2L1 NCOA7 MAGI3 VWA5B1

2.99e-041837845c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIP1 GRAMD2A BAIAP2L1 IRX1

2.99e-04183784ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCellP28-Epithelial|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

3.05e-0418478405811d13bd8a602095a3fcf5e55345edadc7b8bf
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

3.05e-041847847cc5796557379c3d1db078c1aeda40659c6e401c
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BAZ1B CHD4 CXCL2

3.05e-041847841154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

3.05e-04184784cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AHNAK IRX3 MSI1 CXCL2

3.05e-0418478422c18964818fc9c8f18051f836d718937b0d8d12
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

3.11e-0418578468f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GRAMD2A BAIAP2L1 IRX3 IRX1

3.11e-041857842b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

3.11e-041857840c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCellP28-Epithelial-alveolar_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GRAMD2A BAIAP2L1 IRX3 IRX1

3.11e-041857845bb513e569f3a197d55ae2ca683e202daebabeac
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

TGFBR3 SERPING1 IRX3 RGS3

3.11e-0418578416f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCell21-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

TRPM4 NCOA7 IRX3 CXCL2

3.18e-04186784f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCellPND03|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A AHNAK MAGI3 CXCL2

3.24e-04187784b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

3.24e-04187784201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

TRPM4 BAIAP2L1 GNL2 MSI1

3.24e-04187784fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A MYO1D BAIAP2L1 MAGI3

3.24e-0418778458d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellTCGA-Prostate-Primary_Tumor|TCGA-Prostate / Sample_Type by Project: Shred V9

TRPM4 BAIAP2L1 GNL2 MSI1

3.24e-041877843e6a95c912dad5d61e10497ffaafd2b9027cd13a
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP6 COL17A1 GRIA2 CCDC168

3.31e-04188784e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

3.31e-0418878443a0508d2524a5b310e89e9422843dcaab999bc3
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDGFRA SERPING1 IRX3 RGS3

3.31e-04188784de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_early|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MCHR2 IRX3 IRX1 CCNB1

3.38e-04189784a6c62b456982067ad4d224a2efa3919969000693
ToppCelldroplet-Fat-SCAT-30m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR3 AHNAK SERPING1 IRX1

3.38e-041897848161910a19089f8cc5a3f1fda039f41a2488f04f
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRAMD2A BAIAP2L1 IRX3 IRX1

3.38e-041897845f883ef4cc0383142d538ae61f4fb40dfdb8ef18
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBR3 PDGFRA PTPRS SERPING1

3.38e-04189784d531399749409d614adca13d181830c6e3287508
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

AKAP6 EVC2 PDGFRA SERPING1

3.38e-0418978487189275234b5d59484c58acbb14a09903f2b578
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

TGFBR3 PDGFRA PTPRS SERPING1

3.38e-041897840c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCelldroplet-Fat-SCAT|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR3 AHNAK SERPING1 IRX1

3.38e-04189784264c59de2adb8bee5bb57633d79d530a8829617b
ToppCellPND10-Epithelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRAMD2A BAIAP2L1 IRX3 IRX1

3.38e-0418978489349e226a5512833a94b1bf68056a6985fe4afd
DrugAG-012559 [369370-06-9]; Up 200; 10uM; PC3; HT_HG-U133A

TGFBR3 ELOA PDGFRA LONP2 STEEP1 NBN CXCL2

4.48e-061937876920_UP
DiseaseMedulloblastoma

PDGFRA PIK3CG NBN L3MBTL3

8.11e-0650754C0025149
DiseaseChildhood Medulloblastoma

PDGFRA PIK3CG L3MBTL3

1.81e-0443753C0278510
DiseaseMelanotic medulloblastoma

PDGFRA PIK3CG L3MBTL3

1.81e-0443753C1275668
DiseaseMedullomyoblastoma

PDGFRA PIK3CG L3MBTL3

1.81e-0443753C0205833
DiseaseDesmoplastic Medulloblastoma

PDGFRA PIK3CG L3MBTL3

1.81e-0443753C0751291
DiseaseAdult Medulloblastoma

PDGFRA PIK3CG L3MBTL3

1.81e-0443753C0278876
Diseaserectum cancer (is_implicated_in)

NBN CHD4

2.27e-049752DOID:1993 (is_implicated_in)
Diseaseprostate adenocarcinoma (is_marker_for)

PDGFRA CCNB1

2.83e-0410752DOID:2526 (is_marker_for)
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

TDRD15 ZHX3 BAZ1B

3.01e-0451753EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
DiseaseAbruptio Placentae

TDRD15 IRX1

4.14e-0412752EFO_1001754
Diseasemigraine disorder, type 2 diabetes mellitus

ZHX3 NCOA7 SLC28A3

4.86e-0460753MONDO_0005148, MONDO_0005277
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

TDRD15 ZHX3 BAZ1B

7.33e-0469753EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
DiseaseLung diseases

PDGFRA IRX3 IRX1

1.05e-0378753C0024115
DiseaseHypertriglyceridemia

TDRD15 BAZ1B

1.06e-0319752EFO_0004211
Diseasebasophil percentage of granulocytes

GRIP1 CXCL2 RYR1

1.25e-0383753EFO_0007995
Diseasein situ carcinoma (is_marker_for)

PDGFRA CCNB1

1.30e-0321752DOID:8719 (is_marker_for)
Diseaseacute necrotizing pancreatitis (biomarker_via_orthology)

SERPING1 CXCL2

1.99e-0326752DOID:0080998 (biomarker_via_orthology)
DiseaseRS-10-hydroxywarfarin measurement

BAIAP2L1 PIK3CG IRX1

2.02e-0398753EFO_0803330
DiseaseSezary Syndrome

KMT2C IL32

2.15e-0327752C0036920

Protein segments in the cluster

PeptideGeneStartEntry
KMMEKKGTKIQTPAA

TTF1

841

Q15361
NTPAKKEMELLIMTK

COL17A1

351

Q9UMD9
ILKNMFLPQKKMIKE

CUL5

741

Q93034
NPVKMKKIKELLQMS

CWC25

156

Q9NXE8
KGLKTPKTKMKQMTL

BAZ1B

426

Q9UIG0
PKTKMKQMTLLDMAK

BAZ1B

431

Q9UIG0
KLKMPEMNIKAPKIS

AHNAK

2566

Q09666
KFKMPEMNIKAPKIS

AHNAK

3206

Q09666
KFKMPEMNIKAPKIS

AHNAK

4446

Q09666
VQPMMTKIKTVLKSR

DGCR8

281

Q8WYQ5
VITPKMLMSFVLKKN

OR8B8

76

Q15620
LGKKSRLMKTVQTMK

RGS3

506

P49796
EVKKLMDEVIKSMKP

EXOSC8

261

Q96B26
TKGEKIMLAIITKMT

IRX4

171

P78413
KKKMMEEKLHRQPVS

PARP9

686

Q8IXQ6
QKKMKLEVVDKRNPM

L3MBTL3

476

Q96JM7
TKIITLNGKKMTKMP

LRRC69

16

Q6ZNQ3
SRSQPVMKVAVKMLK

PDGFRA

616

P16234
VMKVAVKMLKPTARS

PDGFRA

621

P16234
TVMKDPYKVVMKQSK

GNL2

101

Q13823
AITDPIMKAKMVALK

KMT2C

3091

Q8NEZ4
VKEIKRLKKMPQSMP

LONP2

291

Q86WA8
MKEPTTKAEMLKIIS

MAGEB4

126

O15481
KKIKRMVEKSLPSKM

MAGI3

1356

Q5TCQ9
KNEKEMKIKMTAPVT

HEBP2

76

Q9Y5Z4
KPDVSKQGSKMLTKM

FSIP2

6866

Q5CZC0
FMSLGISIMIKKPQK

GRIA2

516

P42262
MIKNVLSMPIVNKKE

PDE6A

381

P16499
MKLDKKMEVFIPLST

EVC2

101

Q86UK5
KKKVSPDKMIEMQAK

KIF3A

411

Q9Y496
VIAPKMLMNFLVKKK

OR8J3

76

Q8NGG0
NKMVECKKAQPKEVM

MSI1

176

O43347
KSKFQEMRKLISTMP

MED9

91

Q9NWA0
SPKNFKVKMIMKTSV

PTPRS

1036

Q13332
VPKQRVMKLTKMVLV

MCHR2

241

Q969V1
KVSEQLQAKMPMKKE

CCNB1

51

P14635
MKKLKARMVMLLPTS

IL32

11

P24001
LNMMKKQKVKTIFPH

BAIAP2L1

336

Q9UHR4
LNPASPMVKKIIEKM

CXCL2

86

P19875
PMVKKIIEKMLKNGK

CXCL2

91

P19875
TVKKIAPMMAKTIKA

ELOA

776

Q14241
KNSVIKVPMMNSKKY

SERPING1

316

P05155
LALMKKVSKSPLVMD

DYNC1H1

1576

Q14204
MATSVVPKKNEMKKS

ESCO1

251

Q5FWF5
LIPTMTKKMKEALLS

FAM136A

121

Q96C01
VKAMDMKRIKSPNII

CCDC168

3666

Q8NDH2
KMKQEIKEIMSPTPV

GRIP1

986

Q9Y3R0
VIPVVSVQMIKKHKM

GRAMD2A

126

Q8IUY3
AKNPKIAVSKMMMVL

CHD4

191

Q14839
MMNLEKKPAKSILKS

RPRD2

846

Q5VT52
EDNLKKTKLPKTYMM

RYR1

946

P21817
QIKILMKNVKVMPFA

POLR3E

281

Q9NVU0
AVIPKMILRKMDKIK

MTBP

516

Q96DY7
TKGEKIMLAIITKMT

IRX3

156

P78415
QEPPKKVMMTKRTKD

STEEP1

136

Q9H5V9
KMEPVSKNKMKTSLN

TDRD15

1216

B5MCY1
KEKKMVVQKPHGTME

NCOA7

101

Q8NI08
PKEIKVSKMEQKFRM

NBN

381

O60934
TKGEKIMLAIITKMT

IRX1

156

P78414
PVLKTMKSVVEKMKN

HUS1

161

O60921
NPKMELLIPVKKKSM

PDIK1L

286

Q8N165
TEKPKITLKNAMKME

SLC28A3

411

Q9HAS3
LKAKRKVVKMMIIVV

TACR3

291

P29371
MKKMPHFRKQITKQV

STXBP3

331

O00186
NKMVKQVTGKMPILS

PLA2G2D

26

Q9UNK4
SKLKLPMIMKQSQSE

AKAP6

1476

Q13023
KMAKKKSLMDIPESQ

PIK3CG

251

P48736
QKTMKSKMREKVRPK

SF3B2

546

Q13435
MISTKEKNKIPKDSM

PLPPR3

1

Q6T4P5
SKMTPSKNITKKMDK

SYCP2

991

Q9BX26
ISISKTPIMKMMKNK

ZHX1

176

Q9UKY1
MMSEKKKKNPTPESV

ARHGAP19

436

Q14CB8
KTAVLGPTLKNVMMK

ZNF518A

416

Q6AHZ1
ILSMMGQLMKPKKTE

RUVBL1

256

Q9Y265
MTQKGSMKPVKKKKT

ZDHHC23

1

Q8IYP9
MAKKSKSKPMKEILE

PPIP5K2

51

O43314
ITKTPIMKIMKGKAE

ZHX3

181

Q9H4I2
KKLMSTALEMKEKTP

WDR87

2391

Q6ZQQ6
LGPKIVIVSKMMKDV

TRPM4

916

Q8TD43
AMTKKSKSKPMTQIL

PPIP5K1

61

Q6PFW1
MMQNKKTFTKPLAVI

TGFBR3

741

Q03167
LQPKMVKSLKKAMAP

VWA5B1

521

Q5TIE3
KMDPTKQYKVMKTIP

MYO1D

886

O94832