Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of presynapse

PPFIA2 PLS3

3.06e-0521112GO:0099181
GeneOntologyMolecularFunctionpropionate-CoA ligase activity

ACSS1 ACSS3

1.82e-0441112GO:0050218
GeneOntologyMolecularFunctionshort-chain fatty acid-CoA ligase activity

ACSS1 ACSS3

1.82e-0441112GO:0031955
GeneOntologyMolecularFunctionacetate-CoA ligase activity

ACSS1 ACSS3

1.82e-0441112GO:0003987
GeneOntologyCellularComponentmicrofibril

MFAP4 ADAMTSL5 FBN3

4.12e-05131123GO:0001527
GeneOntologyCellularComponentglutamatergic synapse

TNIK SPARC PPFIA2 DAG1 CRTAC1 NBEA LRRC4C ABLIM3 FAAH TENM4 PTPRO SV2B ARC DGCR8

1.20e-0481711214GO:0098978
GeneOntologyCellularComponentlateral plasma membrane

PSG6 SLC6A9 PTPRO PKD1 GNA12

1.23e-04901125GO:0016328
DomainLDLRA_1

TMPRSS4 LRP1B PKD1 TMPRSS7

1.82e-04481104PS01209
DomainLDLRA_2

TMPRSS4 LRP1B PKD1 TMPRSS7

1.97e-04491104PS50068
DomainACAS_N

ACSS1 ACSS3

2.05e-0441102PF16177
DomainAbLIM_anchor

ABLIM3 ABLIM1

2.05e-0441102PF16182
DomainACAS_N

ACSS1 ACSS3

2.05e-0441102IPR032387
DomainAbLIM_anchor

ABLIM3 ABLIM1

2.05e-0441102IPR032402
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNIK UBR2 URB2 LRRC4C SMC5 ARFGEF3 ABLIM1 TENM4 SV2B TMEM181 VCPIP1

1.29e-074071161112693553
Pubmed

Regulation of markers of synaptic function in mouse models of depression: chronic mild stress and decreased expression of VGLUT1.

ARC SLC17A7

1.10e-052116220550627
Pubmed

Identification of polycystin-1 and Gα12 binding regions necessary for regulation of apoptosis.

PKD1 GNA12

1.10e-052116220837139
Pubmed

Phosphorylation-dependent control of Activity-regulated cytoskeleton-associated protein (Arc) protein by TNIK.

TNIK ARC

1.10e-052116234077555
Pubmed

Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells.

PLA2R1 PLA2G4A

1.10e-052116210946309
Pubmed

Gα12 is required for renal cystogenesis induced by Pkd1 inactivation.

PKD1 GNA12

1.10e-052116227505895
Pubmed

TNFAIP3 is anti-inflammatory in the retinal vasculature.

RAPGEF3 TNFAIP3

1.10e-052116236034737
Pubmed

Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.

MAGT1 KLRK1

1.10e-052116223846901
Pubmed

Dynamics of expression patterns of AQP4, dystroglycan, agrin and matrix metalloproteinases in human glioblastoma.

DAG1 AQP4

3.30e-053116222307776
Pubmed

Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.

PKD1 GNA12

3.30e-053116225492927
Pubmed

Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15.

KLRK1 PLA2G4A

3.30e-053116219237603
Pubmed

The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development.

H6PD EPHA2

6.59e-05411628183555
Pubmed

Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein.

DAG1 AQP4

6.59e-054116211717465
Pubmed

Onset of aquaporin-4 expression in the developing mouse brain.

DAG1 AQP4

6.59e-054116224915007
Pubmed

Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice.

DMGDH ARC

6.59e-054116218782777
Pubmed

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.

GLDN DAG1

6.59e-054116225646087
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

TNIK CDC37 ARFGEF3 MISP EPHA2 VCPIP1

7.51e-05209116636779422
Pubmed

Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.

DAG1 SLC6A9 SLC17A7

7.88e-0525116328760865
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNIK PPFIA2 DAG1 NBEA LRRC4C AQP4 LRP1B ARFGEF3 ABLIM1 TENM4 SLC7A5 PSMD14 VCPIP1

1.13e-0411391161336417873
Pubmed

Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.

ABLIM3 ABLIM1

1.64e-046116217194709
Pubmed

Hsp90 is an essential regulator of EphA2 receptor stability and signaling: implications for cancer cell migration and metastasis.

CDC37 EPHA2

1.64e-046116219567782
Pubmed

Characterization of serotonin neurotransmission in knockout mice: implications for major depression.

HTR1A FAAH

1.64e-046116223089640
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CEMIP2 TENM4 TULP4 RCOR3 TMEM181

1.67e-04153116510718198
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

UBR2 PIGS DAG1 H6PD MAGT1 LRP1B CEMIP2 CDC37 PLA2R1 EPHA2 SEMA3B SLC7A5 PLS3

1.91e-0412011161335696571
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

BCOR CDC37 IPO9 EPHA2 SLC7A5

2.06e-04160116531678930
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

CDC37 MISP EPHA2 PLA2G4A SLC7A5 VCPIP1

2.26e-04256116633397691
Pubmed

miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.

ABLIM3 ABLIM1

2.29e-047116222684256
Pubmed

Involvement of aquaporin in thromboxane A2 receptor-mediated, G 12/13/RhoA/NHE-sensitive cell swelling in 1321N1 human astrocytoma cells.

AQP4 GNA12

2.29e-047116219772916
Pubmed

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.

DCT CEMIP2 PTPRO SV2B

2.84e-0494116423431145
Pubmed

Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells.

DAG1 SEMA3B

3.05e-048116211487633
Pubmed

Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice.

SEMA3B SLC17A7

3.05e-048116220006658
Pubmed

Chemerin, a novel adipokine in the regulation of angiogenesis.

TRHDE PI16

3.05e-048116220237162
Pubmed

Characterization of genes modulated during pheomelanogenesis using differential display.

DAG1 DCT

3.91e-04911629636156
Pubmed

A whole genome screen for HIV restriction factors.

MKRN3 DAG1 R3HDML RAPGEF3

4.82e-04108116422082156
Pubmed

Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome.

ACSS1 ACSS3

4.88e-0410116217762044
Pubmed

The transcription factor Bhlhb4 is required for rod bipolar cell maturation.

SV2B SLC17A7

5.95e-0411116215363390
Pubmed

SPARC-like 1 (SC1) is a diversely expressed and developmentally regulated matricellular protein that does not compensate for the absence of SPARC in the CNS.

SPARC AQP4

5.95e-0411116222173850
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TNIK DAG1 CEMIP2 SLC6A9 CASKIN2 EPHA2 SLC7A5 GNA12

6.62e-04569116830639242
Pubmed

NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation.

LRRC4C SLC17A7

7.12e-0412116216980967
Pubmed

Claudin-4 localization in epithelial ovarian cancer.

CEMIP2 EPHA2 SLC7A5

7.92e-0454116336237976
Pubmed

The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15.

SPARC PSG6 H6PD

7.92e-045411638482578
Pubmed

Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci.

PPFIA2 ACSS3

8.40e-0413116225352737
Pubmed

The missense mutation C667F in murine β-dystroglycan causes embryonic lethality, myopathy and blood-brain barrier destabilization.

DAG1 AQP4

8.40e-0413116238616731
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

TNIK DAG1 NBEA TULP4 PKD1 MYO18B

8.50e-04329116617474147
Pubmed

Structural and functional insights into the B30.2/SPRY domain.

WSB1 RANBP10

9.78e-0414116216498413
Pubmed

Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis.

HTR1A SLC17A7

9.78e-0414116232433957
Pubmed

Deletion of astroglial connexins weakens the blood-brain barrier.

DAG1 AQP4

9.78e-0414116222472609
Pubmed

CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells.

PSG6 KLRK1

1.13e-0315116222143889
Pubmed

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

UBR2 RNF126 VCPIP1

1.18e-0362116318775313
Pubmed

Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.

CBLC RNF126 TNFAIP3

1.24e-0363116323105109
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TCAF1 PIGS DAG1 URB2 MAGT1 RNF126 ARFGEF3 IPO9 EPHA2 VCPIP1

1.25e-039421161031073040
Pubmed

Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans.

SMC5 TDP1

1.28e-0316116220339383
Pubmed

CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.

PSG6 KLRK1

1.28e-0316116223696226
Pubmed

Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.

SPARC EPHA2

1.28e-0316116221436445
Pubmed

Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb.

SV2B NQO1

1.28e-0316116217715346
Pubmed

Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts.

AQP4 PLA2R1 SLC17A7

1.30e-0364116312107411
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK RANBP10 TCAF1 NBEA BCOR ABLIM3 ABLIM1 CSNK1A1L ANAPC1 ARC

1.47e-039631161028671696
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

RNF121 PIGS ANGEL1 NBEA CEMIP2 ARFGEF3 EPHA2

1.55e-03504116734432599
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

RFK ACSS1 SEMA3B

1.61e-0369116332238831
Pubmed

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.

ABLIM1 ARC

1.63e-0318116219455133
Pubmed

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.

PPFIA2 NBEA

1.63e-0318116227984743
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

PIGS ANGEL1 RNF126 CDC37 ABLIM1 IPO9 SLC7A5 PSMD14

1.66e-03657116836180527
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

TNIK DAG1 CEMIP2 CASKIN2 EPHA2 SLC7A5

1.70e-03377116638117590
Pubmed

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

TNFAIP3 VCPIP1

1.82e-0319116223827681
Pubmed

Ovarian gene expression in the absence of FIGLA, an oocyte-specific transcription factor.

CPHXL PADI6

1.82e-0319116217567914
Pubmed

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.

PPFIA2 SLC17A7

2.01e-0320116223791195
Pubmed

Genomic analysis of mouse retinal development.

SPARC SLC6A9 IPO9 CSNK1A1L SV2B PKD1 SLC17A7 ETNK1 NKAIN1 TNFAIP3

2.02e-0310061161015226823
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

RNF121 RANBP10 FSD2 ERN2 PKD1 TNFAIP3 TDP1 PLS3

2.16e-03686116829987050
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

NAPSA PSG6 MFAP4

2.21e-0377116316944957
Pubmed

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.

TMPRSS4 TMPRSS7

2.22e-0321116219592578
Pubmed

Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.

DAG1 AQP4

2.22e-0321116225382142
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

TRHDE PIGS H6PD TENM4

2.27e-03164116432409323
Pubmed

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.

SV2B SLC17A7 PSMD14

2.38e-0379116327325702
Pubmed

Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6.

UBR2 RNF126

2.44e-0322116224981174
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

TNIK PPFIA2 NBEA ABLIM1 ARC

2.57e-03281116528706196
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

TNIK SPARC PPFIA2 CDC37 ABLIM1 NQO1 DGCR8

2.73e-03558116735063084
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

RANBP10 SPARC DCT CEMIP2 NQO1

2.86e-03288116538496616
Pubmed

CPEB2-eEF2 interaction impedes HIF-1α RNA translation.

SPARC PIGS

2.90e-0324116222157746
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

PIGS DAG1 MAGT1 CEMIP2

2.92e-03176116428692057
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

DAG1 ABLIM3 CEMIP2 ABLIM1 CASKIN2 EPHA2 VCPIP1

2.93e-03565116725468996
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TNIK DAG1 CEMIP2 ABLIM1 EPHA2 SLC7A5

2.95e-03421116636976175
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TNIK CEMIP2 CDC37 ABLIM1 ANAPC1 SLC7A5 PSMD14 VCPIP1

3.24e-03733116834672954
InteractionEPHA7 interactions

TNIK UBR2 TMPRSS4 NBEA CDC37 MISP MALL EPHA2 SEMA3B PLS3

3.96e-0628211210int:EPHA7
GeneFamilySterile alpha motif domain containing

PPFIA2 CASKIN2 USH1G EPHA2

3.36e-0488684760
CoexpressionGSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP

WSB1 MAGT1 SMC5 CDC37 MISP IPO9 ETNK1

3.13e-052001167M387
CoexpressionGSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP

RNF126 GALNT18 PLA2R1 MISP NQO1 ARC TNFAIP3

3.13e-052001167M5247
CoexpressionGSE17721_CTRL_VS_LPS_24H_BMDC_DN

ANGEL1 SMC5 RNF126 INTS14 ETNK1 MFSD8 PLS3

3.13e-052001167M3704
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP

SPARC DCT FAAH MFAP4 FAR2 ANAPC1 TNFAIP3

3.13e-052001167M10032
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK EPM2A SPARC GLB1L PPFIA2 CEMIP2 USH1G RCOR3

2.62e-081831158709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK EPM2A SPARC GLB1L PPFIA2 CEMIP2 USH1G RCOR3

2.62e-081831158dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE DMGDH PPFIA2 ACSS1 LRP1B ABLIM1 TENM4 PHF21B

3.51e-081901158cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCelldistal-2-Epithelial-Club|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NAPSA FAXC CBLC CRTAC1 AQP4 ARFGEF3 MALL SEMA3B

4.83e-0819811583055c03896fbfac82a3072e51c0c54d68131cf1a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNIK ACSS1 AQP4 LRP1B ABLIM1 ADAMTSL5 RAPGEF3 NQO1

5.22e-0820011587a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPARC ABLIM3 GALNT18 CDC37 CASKIN2 RAPGEF3 SV2B

4.12e-071781157360d7a987f91d6d721487a921824057ec31a7332
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKRN3 ABLIM3 ABLIM1 EML5 RAPGEF3 MALL PHF21B

4.28e-07179115708cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellfacs-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSB1 TMPRSS4 MALL EPHA2 ARC CYP4F22 TNFAIP3

5.15e-071841157dc7f6ee4062856a02423fff8b1cce62d46a9355c
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|368C / Donor, Lineage, Cell class and subclass (all cells)

CRTAC1 NBEA URB2 AQP4 MISP MALL EPHA2

5.75e-071871157b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|368C / Donor, Lineage, Cell class and subclass (all cells)

CRTAC1 NBEA URB2 AQP4 MISP MALL EPHA2

5.75e-07187115761c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC PI16 R3HDML GALNT18 CEMIP2 ADAMTSL5 ARC

5.95e-07188115751c6796a9488c056a10d048082015342c2e037f9
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC PI16 R3HDML GALNT18 CEMIP2 ADAMTSL5 ARC

5.95e-071881157b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 ACSS1 LRP1B GALNT18 ABLIM1 TENM4 PHF21B

6.62e-071911157963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellCF-Epithelial|CF / Disease state, Lineage and Cell class

RFK TMPRSS4 ABLIM3 ABLIM1 MALL EPHA2 PLS3

7.10e-071931157518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCellCF-Epithelial-Epithelial_cell|CF / Disease state, Lineage and Cell class

RFK TMPRSS4 ABLIM3 ABLIM1 MALL EPHA2 PLS3

7.10e-0719311574e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

SPARC AQP4 ABLIM1 MISP SEMA3B PLS3 FBN3

7.61e-07195115707a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SPARC AQP4 ABLIM1 MISP SEMA3B PLS3 FBN3

7.61e-071951157b65511770ed67f7447847e2187555b362988af45
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA WSB1 CRTAC1 AQP4 ARFGEF3 MALL ACSS3

7.88e-0719611577e5addaa844e66f8160e05858c341866a80aed23
ToppCellILEUM-inflamed-(7)_CD36+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SPARC GALNT18 CASKIN2 RAPGEF3 MALL NQO1 PLS3

8.43e-07198115705d6558c7990ad2277db999025a073d29b273dfc
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CBLC TMPRSS4 ERN2 MISP MALL EPHA2 PLS3

8.72e-071991157d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CBLC TMPRSS4 ERN2 MISP MALL EPHA2 PLS3

8.72e-071991157a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CBLC TMPRSS4 ERN2 MISP MALL EPHA2 PLS3

8.72e-071991157644197ff7e3299587881dd678836262e670ed4a8
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CBLC TMPRSS4 ERN2 MISP MALL EPHA2 PLS3

8.72e-0719911572a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CBLC TMPRSS4 ERN2 MISP MALL EPHA2 PLS3

8.72e-071991157fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

ACSS1 HPSE2 AQP4 GALNT18 ABLIM1 PHF21B ACSS3

9.02e-072001157d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

ACSS1 HPSE2 AQP4 GALNT18 ABLIM1 PHF21B ACSS3

9.02e-072001157f861509b54185d89931db64da1b9d81986cc7938
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNIK HPSE2 AQP4 LRP1B ABLIM1 RAPGEF3 NQO1

9.02e-072001157d0812817ef99608994193787a62d39adeb2070ca
ToppCellILEUM-non-inflamed-(7)_CD36+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SPARC GALNT18 CASKIN2 RAPGEF3 MALL NQO1 PLS3

9.02e-07200115745755a597725015dc3ee36f9166f9e82f6f9c603
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

ACSS1 HPSE2 AQP4 GALNT18 ABLIM1 PHF21B ACSS3

9.02e-07200115716f468217427921fa18c6d078ffa990eb019b257
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

ACSS1 HPSE2 AQP4 GALNT18 ABLIM1 PHF21B ACSS3

9.02e-0720011570442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

ACSS1 HPSE2 AQP4 GALNT18 ABLIM1 PHF21B ACSS3

9.02e-07200115701819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TNIK HPSE2 AQP4 LRP1B ABLIM1 RAPGEF3 NQO1

9.02e-072001157cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 NAPSA INTS14 MALL ACSS3 VCPIP1

6.72e-061771156164ffbbf798defa3728197deb1a14b661490e525
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA CBLC ENAM MISP SV2B CYP4F22

6.72e-061771156a58c93be9767e3fe8fbb6b0db1210d3a33aac662
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA CBLC ENAM MISP SV2B CYP4F22

6.72e-0617711563ed383e5c0b15d9d5e75b98cf6d10609f48fc422
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBLC ENAM MISP TENM4 SV2B CYP4F22

6.94e-0617811569b932b677ae05ac6e12cd6ce97789f8c10e4790b
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TMPRSS4 CRTAC1 NBEA ERN2 ARFGEF3 MALL

7.40e-061801156b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNIK GLB1L PPFIA2 GALNT18 CEMIP2 USH1G

7.63e-061811156a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 PPFIA2 TMPRSS4 LRP1B ABLIM1 PLA2G4A

7.63e-06181115622363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TMPRSS4 NBEA ERN2 LRP1B ARFGEF3 EPHA2

7.88e-061821156215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE SPARC PI16 GALNT18 CEMIP2 ADAMTSL5

7.88e-061821156f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

NAPSA AQP4 MISP MALL SEMA3B PLS3

8.13e-06183115631fef35ecf30162662f24d335d8f0cceacc07039
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PPFIA2 LRRC4C LRP1B ARFGEF3 TENM4

8.38e-0618411562cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CBLC R3HDML ARFGEF3 NQO1 ARC ACSS3

8.38e-061841156204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 TMPRSS4 LRP1B ABLIM1 PLA2G4A ETNK1

8.38e-0618411568fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH PPFIA2 LRP1B ABLIM1 TENM4 PHF21B

8.38e-061841156e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PPFIA2 LRRC4C LRP1B ARFGEF3 TENM4

8.38e-061841156ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CBLC R3HDML ARFGEF3 NQO1 ARC ACSS3

8.38e-0618411569365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE PPFIA2 LRRC4C LRP1B ARFGEF3 TENM4

8.38e-0618411562b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA ARFGEF3 TENM4 EML5 MALL PLA2G4A

8.38e-061841156ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBLC R3HDML ARFGEF3 NQO1 ARC ACSS3

8.38e-0618411567cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBLC R3HDML ARFGEF3 NQO1 ARC ACSS3

8.38e-06184115653b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellControl-Epithelial-Goblet|World / Disease state, Lineage and Cell class

CBLC TMPRSS4 ERN2 ARFGEF3 MALL EPHA2

8.65e-0618511569a793e6016295a63820e9d7563f195494ac692e7
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA AQP4 MISP EML5 MALL SEMA3B

8.65e-0618511560c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPM2A PPFIA2 ACSS1 LRP1B ABLIM1 PHF21B

8.65e-061851156898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

8.92e-06186115673cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

AQP4 GALNT18 ABLIM1 SEMA3B PLS3 FBN3

8.92e-06186115609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellfacs-Skin-Anagen-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPM2A SPARC PI16 OSR2 NBEA MFAP4

9.19e-061871156908df5520142d65fe32a003d26be14965082a1ea
ToppCellfacs-Skin-Anagen-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPM2A SPARC PI16 OSR2 NBEA MFAP4

9.19e-061871156c1dfab0b0d7f519b9f13f4e0365ab41c4b2ae1ec
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

9.19e-0618711564d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SPARC AQP4 ABLIM1 MISP SEMA3B FBN3

9.19e-061871156f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

9.19e-0618711565d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

9.19e-0618711565c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

9.19e-06187115693c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCellfacs-Skin-Anagen-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPM2A SPARC PI16 OSR2 NBEA MFAP4

9.19e-061871156b486cc5ac678051fea9d4c7db53b26a5a8427e60
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 TCAF1 HPSE2 TENM4 PLS3 PHF21B

9.19e-061871156c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPARC NUP62CL OSR2 H6PD MFAP4 SLC17A7

9.19e-061871156976b74d081b7fba8620768613cc26f9262cd7b16
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 TMPRSS4 LRP1B GALNT18 ABLIM1 PHF21B

9.48e-0618811562ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

AQP4 GALNT18 PLA2R1 ABLIM1 SEMA3B PLS3

9.77e-0618911565a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.01e-0519011565c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

NAPSA CRTAC1 AQP4 ARFGEF3 MALL EPHA2

1.01e-051901156d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.01e-0519011563a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.01e-051901156b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCellIPF-Epithelial-Goblet|IPF / Disease state, Lineage and Cell class

CBLC TMPRSS4 ERN2 ARFGEF3 MALL EPHA2

1.01e-051901156e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 ACSS1 LRP1B GALNT18 TENM4 PHF21B

1.01e-0519011563dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellIPF-Epithelial-Goblet|World / Disease state, Lineage and Cell class

CBLC TMPRSS4 ERN2 ARFGEF3 MALL EPHA2

1.01e-051901156c29dabf0826663b9d6df51a7af9b76592090e44c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.01e-0519011561c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO4 TRHDE HPSE2 ABLIM3 MFAP4 TENM4

1.04e-05191115614057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

NAPSA TMPRSS4 ERN2 AQP4 ARFGEF3 MALL

1.04e-0519111563c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRHDE TMPRSS4 LRP1B TENM4 RAPGEF3 PHF21B

1.04e-051911156fe55475ce0666ab5122447a813dc2369e24947b8
ToppCelldroplet-Tongue-nan-3m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSR2 TMPRSS4 ABLIM1 MALL EPHA2 CYP4F22

1.04e-051911156abdd93b2313e635f75a750d051a6a01ddc4e2df9
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

NAPSA CRTAC1 AQP4 ARFGEF3 ABLIM1 MALL

1.07e-0519211561bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRTAC1 LRRC4C LRP1B GALNT18 ABLIM1 FAR2

1.07e-05192115652acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.07e-051921156f7e4509003d71f805b9d4587098e90d2897b6739
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.07e-05192115643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIA2 ACSS1 LRP1B GALNT18 ABLIM1 PHF21B

1.07e-051921156562df5e87038c500dd3a003fe5374cb31946b145
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.07e-051921156705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA WSB1 CRTAC1 AQP4 MALL ACSS3

1.10e-051931156136775166ecc38399091f262279180dbe5a1dcd7
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK NAPSA CRTAC1 ARFGEF3 MALL ACSS3

1.10e-051931156fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.10e-051931156b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACSS1 HPSE2 AQP4 RAPGEF3 PHF21B ACSS3

1.10e-05193115640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK NAPSA CRTAC1 ARFGEF3 MALL ACSS3

1.10e-051931156f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRTAC1 LRRC4C LRP1B GALNT18 ABLIM1 FAR2

1.10e-0519311567261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellCTRL-Epithelial-Epithelial_cell|CTRL / Disease state, Lineage and Cell class

TMPRSS4 ABLIM3 ABLIM1 MALL EPHA2 PLS3

1.13e-0519411562bc4deaf2a01a39809fc323962fce4286835209c
ToppCellCTRL-Epithelial|CTRL / Disease state, Lineage and Cell class

TMPRSS4 ABLIM3 ABLIM1 MALL EPHA2 PLS3

1.13e-05194115649dcb31427f370692308f939e23992925708abb7
ToppCellfacs-Heart-RA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM3 CEMIP2 ABLIM1 CASKIN2 RAPGEF3 MALL

1.17e-051951156f4fdcc0b851392086e9618e76ee6a0b540d5fb3c
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMPRSS4 ERN2 ARFGEF3 PLA2R1 ABLIM1 PLS3

1.20e-05196115670384c1da9baed843f414cfd1403ddd586a2db07
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

NAPSA WSB1 CRTAC1 AQP4 ARFGEF3 ACSS3

1.20e-051961156754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

AQP4 ABLIM1 MISP SEMA3B PLS3 FBN3

1.20e-051961156150554fa06868d29b0608189862eef6505ba757f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA WSB1 GLDN CRTAC1 AQP4 MALL

1.20e-051961156006d783a530aa6e1e6545dcc2e6b00bb300fe070
DiseaseDrug habituation

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C0013170
DiseaseDrug abuse

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C0013146
DiseasePrescription Drug Abuse

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C4316881
DiseaseSubstance-Related Disorders

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C0236969
DiseaseDrug Use Disorders

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C0013222
DiseaseDrug Dependence

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C1510472
DiseaseSubstance Dependence

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C0038580
DiseaseSubstance Use Disorders

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.67e-051151085C0029231
DiseaseSubstance abuse problem

ANO4 FAAH PLA2R1 ABLIM1 TMPRSS7

6.95e-051161085C0740858
DiseaseNonorganic psychosis

SLC6A9 TENM4 GNA12 DGCR8

1.22e-04691084C0349204
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

PI16 LRP1B FAAH GNA12

1.78e-04761084EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
Diseasetransitional cell carcinoma (biomarker_via_orthology)

PLA2G4A SLC7A5

2.75e-0471082DOID:2671 (biomarker_via_orthology)
DiseaseSchizophrenia

TNIK HTR1A R3HDML AQP4 SLC6A9 TENM4 EML5 ARC SLC17A7 PLA2G4A DGCR8

3.99e-0488310811C0036341
DiseasePsychotic Disorders

SLC6A9 TENM4 GNA12 DGCR8

5.28e-041011084C0033975
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

TRHDE TNIK TENM4 FBN3

7.27e-041101084EFO_0803335
DiseaseSjogren's Syndrome

TNFAIP3 PHIP

1.01e-03131082C1527336
DiseaseSicca Syndrome

TNFAIP3 PHIP

1.01e-03131082C0086981
Diseaserefractive error

NBEA LRRC4C GALNT18 FAR2 ETNK1 FBN3

1.29e-033261086MONDO_0004892
Diseaseresponse to antipsychotic drug

TNIK NBEA TENM4

1.40e-03601083GO_0097332
Diseaseskin hydration measurement

LRRC4C ABLIM1

2.66e-03211082EFO_0009586
Diseasenose morphology measurement, mouth morphology measurement

ANO4 FBN3

2.66e-03211082EFO_0007843, EFO_0007955
Diseaseresponse to clopidogrel, cardiovascular event measurement

CRTAC1 LRRC4C

3.19e-03231082EFO_0006919, GO_1903493
DiseaseAnhedonia

HTR1A SLC17A7

3.48e-03241082C0178417
Diseasebeta-aminoisobutyric acid measurement

HTR1A FBN3

3.48e-03241082EFO_0010464

Protein segments in the cluster

PeptideGeneStartEntry
SPGQMCGHYTQVVWA

PI16

121

Q6UXB8
DGMTPTLWAAYHGNL

USH1G

31

Q495M9
HPYAAMENWGLSIFV

TRHDE

401

Q9UKU6
QVGMVSGLTYPVAHW

URB2

726

Q14146
RSFGPAVIMGNWENH

AQP4

216

P55087
GEEMYLTGSEVWHPI

ABLIM3

246

O94929
QAWPGMARTIYGDHQ

ACSS1

501

Q9NUB1
KNWQLLAVNHPGYMA

CBLC

226

Q9ULV8
GEEMYLQGSTVWHPD

ABLIM1

321

O14639
EYWLSQIQNHMNGPA

ARC

236

Q7LC44
QIGGHWMHYDGLRNV

C14orf28

271

Q4W4Y0
LYHAVVEPMLWNPSG

C22orf31

216

O95567
MVALFQHSPYWQADG

LINC02910

1

Q8N268
SWEDGHLMLYPVQFL

GLDN

531

Q6ZMI3
EGFTPLMWAAAHGQI

ANKRA2

181

Q9H9E1
HAPWEVLGRYAEQMN

ANO4

166

Q32M45
GWIMTFHNSGVPVYL

DGCR8

306

Q8WYQ5
GTYRLEVVSHMAGPW

FBN3

2771

Q75N90
PLYGNVHSWMNSERV

BCOR

6

Q6W2J9
NGGMLVWSPYHSIPD

RCOR3

26

Q9P2K3
GVNMNRLPGWDKHSY

RANBP10

126

Q6VN20
GYVWNALVHTGPGMN

PGBD4

286

Q96DM1
SYVPMGHVWLEGDNL

IMMP1L

106

Q96LU5
ILGPMFISQVYAHWG

MFSD8

466

Q8NHS3
QMLVKWYNVHSAPGG

ANAPC1

636

Q9H1A4
GLMHGQGTYIWADGL

RSPH10B

116

P0C881
GLMHGQGTYIWADGL

RSPH10B2

116

B2RC85
TVFGHLAQAMWTLPG

FAXC

291

Q5TGI0
LVYHITSGNMNPCNW

FAR2

301

Q96K12
YHLVCMGPEASGWGQ

MISP

31

Q8IVT2
QAPVELYSDWLMTGH

PADI6

466

Q6TGC4
GHQAMHYSRILPNIW

EPM2A

151

O95278
HDQVGFIPGMQGWFN

nan

561

O00370
HPRGIVVDPVNGWMY

LRP1B

646

Q9NZR2
TSGQMWNHIRGPPYA

MAGT1

231

Q9H0U3
AATHIVYPLLQGWVM

MALL

46

Q13021
GVPVMGVYTWHQDGL

ERN2

226

Q76MJ5
MSAQLGYPVVGWHIA

DAG1

286

Q14118
NSWLPYPVAGNMAKH

CD1A

146

P06126
WMNSLGVNPHVNHLY

PLS3

406

P13797
SYHWMGLVHIPTNGS

KLRK1

151

P26718
GNYHLGVMSWIIPVF

SLC7A5

316

Q01650
NTWFKHENYGLMPLN

FMO6P

261

O60774
WITPNGTVMTHGAYK

LRRC4C

386

Q9HCJ2
ILQGGVGIPHMHWYG

CSNK1A1L

66

Q8N752
VGIPHMHWYGQEKDN

CSNK1A1L

71

Q8N752
LVGMPGLEYAHIWIS

OR51A2

16

Q8NGJ7
LVGMPGLEYAHIWIS

OR51A4

16

Q8NGJ6
SWELGNEPNNYRTMH

HPSE2

256

Q8WWQ2
MNHWTLGYPNVHEIT

OSR2

51

Q8N2R0
LMGGDGRYVLNGHWV

ADAMTSL5

241

Q6ZMM2
NGMRPLHYAAWQGRL

CASKIN2

81

Q8WXE0
YSLQGIHGDMNVILW

NQO1

156

P15559
TVFNHWLPGMCYSNI

PTPRO

176

Q16827
SQFILMGLPGIHEWQ

OR56B4

16

Q8NH76
YHMQRCIDSGLWVPN

CDC37

331

Q16543
HPYGKGWDLMQNIMN

EPHA2

46

P29317
HQVLDRNMLGEAGYW

ARFGEF3

791

Q5TH69
VQLGPEWHGMLYSQA

INTS14

326

Q96SY0
WVPNNGVHDRAYVMV

GLB1L

431

Q6UWU2
HVYMAWNIPQEDSGI

GALNT18

416

Q6P9A2
GIPWQYSENEKHGMF

GNA12

116

Q03113
HMPTLLGAIINWLGY

HTR1A

376

P08908
PVVMLEKGYTIHWNG

CEMIP2

1036

Q9UHN6
MVGPHQGVRNYWVAI

DMGDH

381

Q9UI17
GHNGLWYVMQVVSQL

IPO9

736

Q96P70
GNWNGPHRLYLQMST

CRTAC1

311

Q9NQ79
PIWHEGENLNYGMQI

ENAM

821

Q9NRM1
HMEGEVWGLATHPYL

EML5

996

Q05BV3
MVQYELWAALPGASG

FAAH

1

O00519
VAWAMANYIHVPPGS

ETNK1

86

Q9HBU6
SGVLPHSGQLVWYMD

H6PD

771

O95479
NWLLGHLGMYLPNEA

CYP4F22

66

Q6NT55
QQPTWHDQPEMGSHY

C14orf178

21

Q8N769
HLEKQWIPSQEMGYN

CPHXL

141

A0A1W2PPM1
WAHGPSQLMRYVGQN

R3HDML

106

Q9H3Y0
LQTLAYGDMNHEWIG

PPFIA2

1011

O75334
WMAHVLLPYVHGNQS

PKD1

3726

P98161
QTGRPEMVVGWYHSH

PSMD14

101

O00487
YEENPLHFLMGVWGS

PLA2G4A

381

P47712
FHSPRWGGIMVYNVD

PIGS

351

Q96S52
GGLYASAMAWSIIPH

SV2B

246

Q7L1I2
ADVQISVGWMHAGYP

TCAF1

716

Q9Y4C2
SYLWLLNGQNLPMTH

PSG6

176

Q00889
VNGQLVSYGDMAWHV

NBEA

346

Q8NFP9
VMGNLIPVRGHHYWE

FSD2

611

A1L4K1
ADGEYWLGLQNMHLL

MFAP4

106

P55083
LGPWGVLHSNPMDYA

RNF126

166

Q9BV68
VLHSNPMDYAWGANG

RNF126

171

Q9BV68
GYQWAPILANFLHIM

NKAIN1

31

Q4KMZ8
AMPLAGVLVQYSGWS

SLC17A7

221

Q9P2U7
WNTHQPRYSGGCVAM

PLA2R1

606

Q13018
HWSMSSIYGLQPGEV

ACSS3

321

Q9H6R3
LQYHGMPAWKVSGQE

ANGEL1

451

Q9UNK9
LHESDGVLGMSWNYP

TULP4

206

Q9NRJ4
QWVALYGSMLHTDPV

RAPGEF3

471

O95398
NIPYVKAPDTHGNMW

TDP1

591

Q9NUW8
VLQWGEMPTSVAYIH

TNIK

1276

Q9UKE5
HYQPQGDQGEAWAKM

TTC24

146

A2A3L6
YWHQLVEPVRMGEGN

MKRN3

441

Q13064
GVPWTGMLAIVHSYV

PHF21B

406

Q96EK2
WNSYTGQLIHVLMGH

PHIP

451

Q8WWQ0
YLMVIEIPVQGWDHG

TNFAIP3

306

P21580
PTPWTAHLGMYVQGN

TMPRSS7

656

Q7RTY8
LGIWQTVNELHDPMY

TMEM181

431

Q9P2C4
AHKEGPMHQWVSYQG

SEMA3B

356

Q13214
MYIFPVHWQFGQLDQ

SPARC

226

P09486
DSGGPLMYQSDQWHV

TMPRSS4

386

Q9NRS4
YWPQGMSQQHSEGSR

TTC41P

1111

Q6P2S7
FGLNWHLQPMEGQMY

TENM4

366

Q6N022
WHGAYNSGLLPQLMA

SLC6A9

61

P48067
SNPWERPHVMYGQLL

RNF121

286

Q9H920
GDVHKMVVSIGWNPY

RFK

56

Q969G6
AWPQELAPIGHNRMY

DCT

416

P40126
DVWSYAKGLPHMFQQ

VCPIP1

906

Q96JH7
GLPAHIGSMAQRAYW

MYO18B

631

Q8IUG5
YIWDPHNGDILMEFG

WSB1

281

Q9Y6I7
VYNGPHMLEPNTWNL

SMC5

1071

Q8IY18
QHVLLGPMEWYLCGE

UBR2

66

Q8IWV8
MGTILQWAVEHNGYA

UBR2

901

Q8IWV8
VMTYGHLEGLINEWN

NUP62CL

71

Q9H1M0
AYWQIHMERVKVGPG

NAPSA

256

O96009