Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	2.67e-15	37	65	9	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	3.49e-15	38	65	9	GO:0070001
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-8 ERVK-7 DDX3X	5.87e-07	21	65	4	GO:0035613
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 RHBDD1 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	1.20e-06	430	65	10	GO:0004175
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-8 ERVK-7	5.33e-06	11	65	3	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	1.17e-05	14	65	3	GO:0003964
GeneOntologyMolecularFunction	threonine-tRNA ligase activity	TARS3 TARS2	3.12e-05	3	65	2	GO:0004829
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 RHBDD1 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	4.67e-05	654	65	10	GO:0008233
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	CNOT6 ERVK-6 CNOT6L PTPRO PDE8B ERVK-8 ERVK-7 TARS2 OGG1 ABHD12 ALPI	5.34e-05	807	65	11	GO:0016788
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	CNOT6 ERVK-6 TARS3 CNOT6L ERVK-8 ERVK-7 TARS2 DDX3X	6.03e-05	417	65	8	GO:0140098
GeneOntologyMolecularFunction	RNA nuclease activity	CNOT6 ERVK-6 CNOT6L ERVK-8 ERVK-7	8.10e-05	136	65	5	GO:0004540
GeneOntologyMolecularFunction	nuclease activity	CNOT6 ERVK-6 CNOT6L ERVK-8 ERVK-7 OGG1	1.05e-04	231	65	6	GO:0004518
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	CNOT6 ERVK-6 TARS3 CNOT6L ERVK-8 ERVK-7 TARS2 OGG1 DDX3X	2.30e-04	645	65	9	GO:0140640
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	2.36e-04	37	65	3	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	2.56e-04	38	65	3	GO:0034061
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	4.52e-04	46	65	3	GO:0016893
GeneOntologyMolecularFunction	poly(A)-specific ribonuclease activity	CNOT6 CNOT6L	7.95e-04	13	65	2	GO:0004535
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-8 ERVK-7 OGG1	1.01e-03	136	65	4	GO:0004519
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR1 TPCN1	1.54e-03	18	65	2	GO:0015278
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERVK-6 ERVK-8 ERVK-7 OGG1 DDX3X	1.63e-03	262	65	5	GO:0140097
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-8 ERVK-7	2.18e-03	79	65	3	GO:0004521
GeneOntologyMolecularFunction	structural molecule activity	ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	2.28e-03	891	65	9	GO:0005198
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	6.65e-06	85	64	5	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	6.65e-06	85	64	5	GO:0000768
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-8 ERVK-7	7.97e-06	13	64	3	GO:0015074
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	8.33e-06	89	64	5	GO:0006949
GeneOntologyBiologicalProcess	viral process	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24 DDX3X TPCN1	1.26e-05	464	64	9	GO:0016032
GeneOntologyBiologicalProcess	threonyl-tRNA aminoacylation	TARS3 TARS2	2.84e-05	3	64	2	GO:0006435
GeneOntologyBiologicalProcess	positive regulation of cytoplasmic mRNA processing body assembly	CNOT6 CNOT6L	1.41e-04	6	64	2	GO:0010606
Domain	ThrRS_core	TARS3 TARS2	2.64e-05	3	56	2	IPR033728
Domain	Thr-tRNA-ligase_IIa	TARS3 TARS2	2.64e-05	3	56	2	IPR002320
Domain	DUF1908	MAST2 MAST3	5.28e-05	4	56	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST2 MAST3	5.28e-05	4	56	2	IPR015022
Domain	MAST_pre-PK_dom	MAST2 MAST3	5.28e-05	4	56	2	IPR023142
Domain	-	MAST2 MAST3	5.28e-05	4	56	2	1.20.1480.20
Domain	TGS	TARS3 TARS2	1.31e-04	6	56	2	IPR004095
Domain	TGS	TARS3 TARS2	1.31e-04	6	56	2	PF02824
Domain	TGS-like	TARS3 TARS2	1.84e-04	7	56	2	IPR012676
Domain	tRNA_SAD	TARS3 TARS2	1.84e-04	7	56	2	SM00863
Domain	tRNA_SAD	TARS3 TARS2	1.84e-04	7	56	2	IPR012947
Domain	tRNA_SAD	TARS3 TARS2	1.84e-04	7	56	2	PF07973
Domain	Thr/Ala-tRNA-synth_IIc_edit	TARS3 TARS2	2.44e-04	8	56	2	IPR018163
Domain	BEACH_dom	WDR81 NSMAF	3.14e-04	9	56	2	IPR000409
Domain	BEACH	WDR81 NSMAF	3.14e-04	9	56	2	PS50197
Domain	Beach	WDR81 NSMAF	3.14e-04	9	56	2	PF02138
Domain	-	WDR81 NSMAF	3.14e-04	9	56	2	1.10.1540.10
Domain	Beach	WDR81 NSMAF	3.14e-04	9	56	2	SM01026
Domain	HGTP_anticodon	TARS3 TARS2	3.14e-04	9	56	2	PF03129
Domain	-	DNAI1 WDR81 NUP43 BBS1 NSMAF WDR48	4.71e-04	333	56	6	2.130.10.10
Domain	aa-tRNA-synt_IIb	TARS3 TARS2	4.77e-04	11	56	2	IPR002314
Domain	tRNA-synt_2b	TARS3 TARS2	4.77e-04	11	56	2	PF00587
Domain	-	TARS3 TARS2	4.77e-04	11	56	2	3.40.50.800
Domain	WD40/YVTN_repeat-like_dom	DNAI1 WDR81 NUP43 BBS1 NSMAF WDR48	4.86e-04	335	56	6	IPR015943
Domain	Beta-grasp_dom	TARS3 TARS2	7.85e-04	14	56	2	IPR012675
Domain	-	TARS3 TARS2	7.85e-04	14	56	2	3.10.20.30
Domain	Anticodon-bd	TARS3 TARS2	7.85e-04	14	56	2	IPR004154
Domain	WD40	DNAI1 WDR81 NUP43 NSMAF WDR48	1.06e-03	259	56	5	PF00400
Domain	WD40	DNAI1 WDR81 NUP43 NSMAF WDR48	1.23e-03	268	56	5	SM00320
Domain	aa-tRNA-synth_II	TARS3 TARS2	1.31e-03	18	56	2	IPR006195
Domain	AA_TRNA_LIGASE_II	TARS3 TARS2	1.31e-03	18	56	2	PS50862
Domain	WD40_repeat	DNAI1 WDR81 NUP43 NSMAF WDR48	1.32e-03	272	56	5	IPR001680
Domain	WD_REPEATS_1	DNAI1 WDR81 NUP43 NSMAF WDR48	1.45e-03	278	56	5	PS00678
Domain	WD_REPEATS_2	DNAI1 WDR81 NUP43 NSMAF WDR48	1.47e-03	279	56	5	PS50082
Domain	WD_REPEATS_REGION	DNAI1 WDR81 NUP43 NSMAF WDR48	1.47e-03	279	56	5	PS50294
Domain	WD40_repeat_dom	DNAI1 WDR81 NUP43 NSMAF WDR48	1.94e-03	297	56	5	IPR017986
Domain	G_patch	ERVK-6 TFIP11	2.15e-03	23	56	2	SM00443
Domain	G_patch_dom	ERVK-6 TFIP11	2.15e-03	23	56	2	IPR000467
Domain	G_PATCH	ERVK-6 TFIP11	2.15e-03	23	56	2	PS50174
Domain	G-patch	ERVK-6 TFIP11	2.15e-03	23	56	2	PF01585
Domain	-	CNOT6 CNOT6L	2.74e-03	26	56	2	3.60.10.10
Domain	Exo_endo_phos	CNOT6 CNOT6L	2.74e-03	26	56	2	PF03372
Domain	Endo/exonuclease/phosphatase	CNOT6 CNOT6L	2.95e-03	27	56	2	IPR005135
Domain	EF-hand_8	CALU RYR1	4.66e-03	34	56	2	PF13833
Domain	Pkinase_C	MAST2 MAST3	7.04e-03	42	56	2	PF00433
Pathway	WP_JOUBERT_SYNDROME	B9D2 ARR3 BBS1 CEP164	7.47e-05	76	42	4	M39835
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-18 ERVK-19 ERVK-7 ERVK-21	2.11e-14	5	66	5	12629516
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24	1.69e-13	94	66	9	21542922
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19 ERVK-21 ERVK-9	1.65e-11	12	66	5	14557543
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-18 ERVK-21 ERVK-25 ERVK-9 ERVK-24	1.77e-10	18	66	5	18664271
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-18 ERVK-19	6.53e-09	3	66	3	10516026
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-24	2.61e-08	4	66	3	10469592
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-19 ERVK-9	1.30e-07	6	66	3	15063128
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-19 ERVK-21	7.76e-07	10	66	3	12970426
Pubmed	KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.	DNAI1 ARR3 SYNE1	1.84e-06	13	66	3	21177258
Pubmed	Dual inhibition of phosphoinositide 3-kinases delta and gamma reduces chronic B cell activation and autoantibody production in a mouse model of lupus.	PLEKHA1 PLEKHA2	3.55e-06	2	66	2	37234154
Pubmed	Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.	PLEKHA1 PLEKHA2	3.55e-06	2	66	2	21204784
Pubmed	The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.	CNOT6 CNOT6L	3.55e-06	2	66	2	21233283
Pubmed	CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.	CNOT6 CNOT6L	3.55e-06	2	66	2	34788619
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	3.55e-06	2	66	2	9060628
Pubmed	Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.	PLEKHA1 PLEKHA2	3.55e-06	2	66	2	22777911
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	3.55e-06	2	66	2	9460924
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	3.55e-06	2	66	2	11672541
Pubmed	Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.	CNOT6 CNOT6L DDX3X	9.80e-06	22	66	3	18377426
Pubmed	Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo.	PLEKHA1 PLEKHA2	1.06e-05	3	66	2	11802782
Pubmed	Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.	CNOT6 CNOT6L	1.06e-05	3	66	2	30926667
Pubmed	TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor.	PLEKHA1 PLEKHA2	1.06e-05	3	66	2	12101241
Pubmed	CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte.	CNOT6 CNOT6L	1.06e-05	3	66	2	30478191
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-9	1.06e-05	3	66	2	9971820
Pubmed	B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.	PLEKHA1 PLEKHA2	2.12e-05	4	66	2	27859053
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-19	2.12e-05	4	66	2	7983737
Pubmed	Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.	PLEKHA1 PLEKHA2	2.12e-05	4	66	2	14516276
Pubmed	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.	MAST2 MAST3	2.12e-05	4	66	2	15951562
Pubmed	Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.	CNOT6 CNOT6L	2.12e-05	4	66	2	35385705
Pubmed	The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.	CNOT6 CNOT6L	3.53e-05	5	66	2	22977175
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	3.53e-05	5	66	2	11401426
Pubmed	Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition.	CNOT6 CNOT6L	3.53e-05	5	66	2	35390160
Pubmed	Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.	CNOT6 CNOT6L	5.29e-05	6	66	2	31924127
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CNOT6 OGT CNOT6L CALU SYNE1 BSDC1 NUP43 TFIP11 OGG1 STAG2	6.12e-05	1155	66	10	20360068
Pubmed	ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.	RYR1 TPCN1	9.86e-05	8	66	2	30563862
Pubmed	Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.	CNOT6 CNOT6L	1.27e-04	9	66	2	21078877
Pubmed	Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development.	CNOT6 CNOT6L	1.27e-04	9	66	2	21741365
Pubmed	Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	B9D2 BBS1 CEP164	1.35e-04	52	66	3	20301743
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TARS3 OGT HECTD2 SYNE1 TTLL5 NUP43 TFIP11 LRP1B ABHD12 DDX3X	1.47e-04	1285	66	10	35914814
Pubmed	mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.	CNOT6 CNOT6L	1.58e-04	10	66	2	27618784
Pubmed	Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth.	CNOT6 CNOT6L	2.31e-04	12	66	2	17452450
Pubmed	Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation.	CNOT6 CNOT6L	2.31e-04	12	66	2	31320642
Pubmed	Human Ccr4-Not complexes contain variable deadenylase subunits.	CNOT6 CNOT6L	2.31e-04	12	66	2	19558367
Pubmed	O-GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β-catenin signalling.	CNOT6 OGT	2.73e-04	13	66	2	37070251
Pubmed	The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis.	CNOT6 CNOT6L	3.18e-04	14	66	2	34026442
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	DNAI1 SYNE1	3.18e-04	14	66	2	19874786
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	CNOT6 CNOT6L	3.67e-04	15	66	2	21981923
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	ERVK-6 KIAA0825 GUSBP1	4.00e-04	75	66	3	15372022
Pubmed	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.	PLEKHA1 PLEKHA2	4.74e-04	17	66	2	11001876
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	TMEM132D PLD5 LRP1B NSMAF	5.68e-04	199	66	4	23382691
Pubmed	Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.	MAST2 MAST3	5.94e-04	19	66	2	30449657
Pubmed	Recruitment of the human TREX complex to mRNA during splicing.	RBM15 DDX3X	6.59e-04	20	66	2	15998806
Pubmed	RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.	CNOT6 CNOT6L	6.59e-04	20	66	2	34887419
Pubmed	Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.	CNOT6L PLD5	7.28e-04	21	66	2	24057671
Pubmed	Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.	LIPT1 SYNE1 BBS1	9.80e-04	102	66	3	21926972
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	RBM15 SYNE1 MAST2 DDX3X	1.04e-03	234	66	4	36243803
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TTLL5 BSDC1 NUP43 MAST2 LRP1B CEP164 DDX3X	1.16e-03	853	66	7	28718761
Pubmed	Bardet-Biedl Syndrome Overview	BBS1 CEP164	1.21e-03	27	66	2	20301537
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	RBM15 TFIP11 DDX3X	1.35e-03	114	66	3	31553912
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	OGT TFIP11 TARS2 MAST2 DDX3X WDR48	1.46e-03	650	66	6	38777146
Pubmed	Identification of proteins that interact with alpha A-crystallin using a human proteome microarray.	ANKRD44 NUP43 DDX3X	1.49e-03	118	66	3	24453475
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	RBM15 OGT STAG2 WDR48	1.80e-03	272	66	4	31010829
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	OGT MAST2 MAST3	1.88e-03	128	66	3	25332235
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDR81 NSMAF	2.06e-04	9	44	2	1230
GeneFamily	CCR4-NOT transcription complex	CNOT6 CNOT6L	3.14e-04	11	44	2	1023
GeneFamily	WD repeat domain containing	DNAI1 WDR81 NUP43 NSMAF WDR48	4.21e-04	262	44	5	362
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	TMEM132D WDR81 MYO16 RYR1	9.65e-04	181	44	4	694
Disease	amino acid metabolic disorder (implicated_via_orthology)	TARS3 TARS2	2.12e-05	4	56	2	DOID:9252 (implicated_via_orthology)
Disease	Hyporeflexia	PMP22 ABHD12	5.28e-05	6	56	2	C0151888
Disease	neuroticism measurement, cognitive function measurement	KIAA0825 PTPRO HECTD2 CALU PLEKHA1 LRP1B MAST3	9.46e-05	566	56	7	EFO_0007660, EFO_0008354
Disease	blood pressure	SYNE1 MYO16	7.98e-04	22	56	2	EFO_0004325
Disease	diffusing capacity of the lung for carbon monoxide	CNOT6L LRP1B CEP164	8.16e-04	96	56	3	EFO_0009369
Disease	Ciliopathies	B9D2 BBS1 CEP164	1.21e-03	110	56	3	C4277690
Disease	Polydactyly	B9D2 BBS1 CEP164	1.45e-03	117	56	3	C0152427
Disease	asthma, response to diisocyanate	TMEM132D GUSBP1 LRP1B RYR1	1.53e-03	261	56	4	EFO_0006995, MONDO_0004979
Disease	Papillary Renal Cell Carcinoma	OGG1 LRP1B RYR1	1.87e-03	128	56	3	C1306837
Disease	Renal Cell Carcinoma	OGG1 LRP1B RYR1	1.87e-03	128	56	3	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	OGG1 LRP1B RYR1	1.87e-03	128	56	3	C1266043
Disease	Chromophobe Renal Cell Carcinoma	OGG1 LRP1B RYR1	1.87e-03	128	56	3	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	OGG1 LRP1B RYR1	1.87e-03	128	56	3	C1266044

Protein segments in the cluster

Peptide	Gene	Start	Entry
PQIYNESEHHWDMVR	ERVK-18	451	O42043
TPQIYNESEHHWDMV	ERVK-19	561	O71037
TPQIYNDSEHHWDMV	ERVK-8	561	Q902F8
PQIYNESEHHWDMVR	ERVK-9	561	Q9UKH3
MVPAAVSHSEFWHRY	BSDC1	176	Q9NW68
ADAPIVAHLWEYVMS	CPT1A	476	P50416
YDVWSHDVTLANHME	ADCY4	386	Q8NFM4
DMYSHDGNTDEPEWV	CALU	216	O43852
YDAHNMSVDTVSWNP	DNAI1	536	Q9UI46
LQAWMDREVHYHGEP	ARR3	196	P36575
EAEMWEVHFHPSNPE	NUP43	261	Q8NFH3
QYESLDAAHAAWTHM	RBM15	496	Q96T37
DQMWYEDALASSHPI	ABHD12	156	Q8N2K0
EVPSWLENMAYEHHY	DDX3X	566	O00571
MYWTVVGDHSHIEEA	LRP1B	4041	Q9NZR2
HGPDAEHYWSLVAMA	GLTPD2	141	A6NH11
MDWDDEYSHNSFDLH	KIAA0825	1	Q8IV33
HQDEDFWTPMHIACA	MYO16	121	Q9Y6X6
HEPRWSYRAGHMEEA	FNDC9	141	Q8TBE3
VYQNLAVEDWIHDHM	LIPT1	41	Q9Y234
DHIDLMEEYHTWQNF	HECTD2	346	Q5U5R9
DAWDAFAHLPALMQH	PDE8B	846	O95263
PELAMMHCSYWDHDS	FOXL2	351	P58012
EEMEEGSLSWRVYHH	ABCC11	781	Q96J66
ALHWAAYMGHLDVVA	ANKRD44	176	Q8N8A2
PVDVHMWHIAQRDYS	OGG1	266	O15527
TPQIYNESEHHWDMV	ERVK-7	1321	P63135
SIDHKAENDFWMYDH	KBTBD8	351	Q8NFY9
DVMHFNYTAWPDHGV	PTPRO	1091	Q16827
HTVNRNWYSDADMPA	ALPI	181	P09923
EMHSSYFHIAAWAIP	FZD4	341	Q9ULV1
PQIYNESEHHWDMVR	ERVK-24	451	P61566
TPQIYNESEHHWDMV	ERVK-25	561	P61570
TPQIYNESEHHWDMV	ERVK-6	561	Q69384
PQIYNESEHHWDMVR	ERVK-7	451	P61567
ENWIMPAVYAGHFSH	C5orf22	81	Q49AR2
PQIYNESEHHWDMVR	ERVK-21	561	P61565
GDSDVYTVHHMVWHV	MAST2	1126	Q6P0Q8
MGDSDVYTVHHVVWS	MAST3	971	O60307
HHVAEHTAESYMLQW	NSMAF	291	Q92636
TPQIYNESEHHWDMV	HERVK_113	561	Q902F9
YLMHEHPASLYSWED	GUSBP1	66	Q15486
IGDMAYWSHPIDLHF	B9D2	51	Q9BPU9
SKWLDAHYDPMANIH	BBS1	21	Q8NFJ9
WVTPDYHQHDMSFDL	RYR1	1451	P21817
LVANAHMHWDPEYSD	CNOT6	356	Q9ULM6
LQMWEHYAAGNKPDH	OGT	1021	O15294
ADAVIVHHWDIMYNP	FUT5	116	Q11128
FYVQADSPEDMHSWI	PLEKHA2	276	Q9HB19
VYWHSSAHILGEAME	TARS3	231	A2RTX5
GHWEHYQEDMFAVQP	TARS2	366	Q9BW92
SPLHHADDWHLYFNM	RHBDD1	71	Q8TEB9
HEWLSASPHEGFEQM	PLD5	6	Q8N7P1
DHLMYLDAVHEFTDW	SYNE1	2841	Q8NF91
PFEEQEGMSHSHDWV	TMEM132D	951	Q14C87
MQPQESHVHYSRWED	SMIM1	1	B2RUZ4
QSMWDHPCDEHYRSL	CEP164	81	Q9UPV0
NQHPDVFYLMEPAWH	CHST6	61	Q9GZX3
VANAHMHWDPEYSDV	CNOT6L	356	Q96LI5
PYIASMEHHTDWVND	WDR48	66	Q8TAF3
SELHEHAAYLVDSMW	STAG2	471	Q8N3U4
SSPAHNWEMNYQEAA	TPCN1	61	Q9ULQ1
TFYVQADSPEEMHSW	PLEKHA1	266	Q9HB21
MSAAAIYTVRHPEWH	PMP22	111	Q01453
NPHQQHMDAFYWVID	TFIP11	626	Q9UBB9
HVRAQWEPHEYPASM	WDR81	466	Q562E7
FHEVHPSSTDYNLMW	TTLL5	86	Q6EMB2
HDHWRLEYLMDFNPA	ZFTA	106	C9JLR9