Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kinase activity	ERBB4 RIPK1 WEE1 STK26 PAK4 HUNK PFKL RET WNK1 PAPSS1 MELK ITPKA ITPKB PALS1 NEK1 NEK2 MYO3A GUCY2F N4BP2 MAST1 AKT2 WNK2 MAST3	5.28e-08	764	161	23	GO:0016301
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	ERBB4 RIPK1 WEE1 STK26 PAK4 HUNK PFKL RET WNK1 PAPSS1 MELK ITPKA ITPKB NEK1 NEK2 MYO3A GUCY2F N4BP2 MAST1 AKT2 WNK2 MAST3	6.26e-08	709	161	22	GO:0016773
GeneOntologyMolecularFunction	pyrophosphatase activity	RERG DNAH3 KIF12 RABL3 NUDT4B KIF9 RAB9A ARL10 NUDT4 GSPT2 FBH1 CLPB GNA13 DDX54 RAB40C DDX23 GNA11 GNA12 RAB40B GNAQ KIF13A RAB1A DNAH6 DNAH11	6.84e-08	839	161	24	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RERG DNAH3 KIF12 RABL3 NUDT4B KIF9 RAB9A ARL10 NUDT4 GSPT2 FBH1 CLPB GNA13 DDX54 RAB40C DDX23 GNA11 GNA12 RAB40B GNAQ KIF13A RAB1A DNAH6 DNAH11	6.99e-08	840	161	24	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RERG DNAH3 KIF12 RABL3 NUDT4B KIF9 RAB9A ARL10 NUDT4 GSPT2 FBH1 CLPB GNA13 DDX54 RAB40C DDX23 GNA11 GNA12 RAB40B GNAQ KIF13A RAB1A DNAH6 DNAH11	6.99e-08	840	161	24	GO:0016818
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RERG DNAH3 KIF12 RABL3 KIF9 RAB9A ARL10 GSPT2 FBH1 CLPB GNA13 DDX54 RAB40C DDX23 GNA11 GNA12 RAB40B GNAQ KIF13A RAB1A DNAH6 DNAH11	2.91e-07	775	161	22	GO:0017111
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	ERBB4 RIPK1 WEE1 STK26 PAK4 HUNK PFKL RET WNK1 PAPSS1 MELK ITPKA ITPKB PALS1 NEK1 PARP1 NEK2 MYO3A GUCY2F N4BP2 MAST1 AKT2 WNK2 MAST3	5.25e-07	938	161	24	GO:0016772
GeneOntologyMolecularFunction	microtubule motor activity	DNAH3 KIF12 KIF9 DNAH17 KIF13A DNAH6 DNAH11	1.52e-06	70	161	7	GO:0003777
GeneOntologyMolecularFunction	protein kinase activity	ERBB4 RIPK1 WEE1 STK26 PAK4 HUNK RET WNK1 MELK ITPKA NEK1 NEK2 MYO3A GUCY2F MAST1 AKT2 WNK2 MAST3	1.76e-06	600	161	18	GO:0004672
GeneOntologyMolecularFunction	GTP binding	RERG RABL3 RAB9A ARL10 GSPT2 GIMAP8 GUCY2F GNA13 RAB40C GNA11 GNA12 RAB40B GNAQ RAB1A	4.28e-06	397	161	14	GO:0005525
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH3 KIF12 MYO3A KIF9 DNAH17 KIF13A DNAH6 DNAH11	5.18e-06	118	161	8	GO:0003774
GeneOntologyMolecularFunction	G protein activity	RERG GNA13 GNA11 GNA12 GNAQ RAB1A	7.92e-06	59	161	6	GO:0003925
GeneOntologyMolecularFunction	protein serine kinase activity	RIPK1 STK26 PAK4 HUNK WNK1 MELK NEK1 NEK2 MYO3A MAST1 AKT2 WNK2 MAST3	8.10e-06	363	161	13	GO:0106310
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH17 DNAH6 DNAH11	1.14e-05	18	161	4	GO:0008569
GeneOntologyMolecularFunction	guanyl ribonucleotide binding	RERG RABL3 RAB9A ARL10 GSPT2 GIMAP8 GUCY2F GNA13 RAB40C GNA11 GNA12 RAB40B GNAQ RAB1A	1.34e-05	439	161	14	GO:0032561
GeneOntologyMolecularFunction	guanyl nucleotide binding	RERG RABL3 RAB9A ARL10 GSPT2 GIMAP8 GUCY2F GNA13 RAB40C GNA11 GNA12 RAB40B GNAQ RAB1A	1.34e-05	439	161	14	GO:0019001
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	RIPK1 STK26 PAK4 HUNK WNK1 MELK ITPKA NEK1 NEK2 MYO3A MAST1 AKT2 WNK2 MAST3	1.60e-05	446	161	14	GO:0004674
GeneOntologyMolecularFunction	GTPase activity	RERG RABL3 RAB9A ARL10 GSPT2 GNA13 RAB40C GNA11 GNA12 RAB40B GNAQ RAB1A	2.17e-05	341	161	12	GO:0003924
GeneOntologyMolecularFunction	G-protein beta/gamma-subunit complex binding	GNA13 GNA11 GNA12 GNAQ	4.51e-05	25	161	4	GO:0031683
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH3 DNAH17 DNAH6 DNAH11	7.17e-05	28	161	4	GO:0051959
GeneOntologyMolecularFunction	D5 dopamine receptor binding	GNA13 GNA12	1.93e-04	3	161	2	GO:0031752
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH3 DNAH17 DNAH6 DNAH11	2.19e-04	37	161	4	GO:0045505
GeneOntologyMolecularFunction	inositol-1,4,5-trisphosphate 3-kinase activity	ITPKA ITPKB	3.84e-04	4	161	2	GO:0008440
GeneOntologyMolecularFunction	alkylglycerophosphoethanolamine phosphodiesterase activity	GNA11 GNAQ	6.36e-04	5	161	2	GO:0047391
GeneOntologyMolecularFunction	inositol tetrakisphosphate kinase activity	ITPKA ITPKB	6.36e-04	5	161	2	GO:0051765
GeneOntologyMolecularFunction	inositol trisphosphate kinase activity	ITPKA ITPKB	6.36e-04	5	161	2	GO:0051766
GeneOntologyMolecularFunction	endopolyphosphatase activity	NUDT4B NUDT4	6.36e-04	5	161	2	GO:0000298
GeneOntologyMolecularFunction	bis(5'-adenosyl)-hexaphosphatase activity	NUDT4B NUDT4	6.36e-04	5	161	2	GO:0034431
GeneOntologyMolecularFunction	diphosphoinositol-polyphosphate diphosphatase activity	NUDT4B NUDT4	6.36e-04	5	161	2	GO:0008486
GeneOntologyMolecularFunction	microtubule binding	MAP1A EML6 KIF12 CLIP1 KIF9 ABRAXAS1 MAST1 EML1 KIF13A	9.07e-04	308	161	9	GO:0008017
GeneOntologyMolecularFunction	bis(5'-adenosyl)-pentaphosphatase activity	NUDT4B NUDT4	9.49e-04	6	161	2	GO:0034432
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the aldehyde or oxo group of donors	HAO1 DBT FAR1 ALDH9A1	1.08e-03	56	161	4	GO:0016903
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	HS3ST6 HS3ST2	1.32e-03	7	161	2	GO:0008467
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 KIF12 MYO3A KIF9 FBH1 CLPB DNAH17 DDX54 DDX23 KIF13A DNAH6 TOP2A DNAH11	1.45e-03	614	161	13	GO:0140657
GeneOntologyMolecularFunction	tubulin binding	MAP1A EML6 KIF12 CLIP1 KIF9 ABRAXAS1 MAST1 TPPP3 EML1 KIF13A	2.53e-03	428	161	10	GO:0015631
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH3 KIF12 KIF9 FBH1 CLPB DDX54 DDX23 KIF13A DNAH6 DNAH11	3.14e-03	441	161	10	GO:0016887
GeneOntologyMolecularFunction	cytoskeletal protein binding	CACNA1D TRIM2 KLHL1 MAP1A DCTN2 EML6 KIF12 CLIP1 OPHN1 KPTN MYO3A KIF9 ABRAXAS1 SIPA1L1 MAST1 TPPP3 EML1 KIF13A	3.35e-03	1099	161	18	GO:0008092
GeneOntologyMolecularFunction	potassium channel inhibitor activity	WNK1 WNK2	3.39e-03	11	161	2	GO:0019870
GeneOntologyMolecularFunction	inositol phosphate kinase activity	ITPKA ITPKB	3.39e-03	11	161	2	GO:0180030
GeneOntologyBiologicalProcess	neuron development	PLXNA3 LRP12 KLHL1 MAP1A WEE1 WNT7A PAK4 LAMA3 MPDZ CC2D1A RET ARHGEF25 WNK1 CLIP1 OPHN1 ITPKA PALS1 MYO3A SLITRK2 ZPR1 SIPA1L1 PJVK RTCA LRP4 MFSD8 SEMA6A GNAQ CTNND2	8.64e-06	1463	161	28	GO:0048666
GeneOntologyBiologicalProcess	inositol phosphate metabolic process	NUDT4B ITPKA ITPKB NUDT4 SYNJ2	5.26e-05	52	161	5	GO:0043647
GeneOntologyBiologicalProcess	neuron projection development	PLXNA3 LRP12 KLHL1 MAP1A WEE1 WNT7A PAK4 LAMA3 MPDZ CC2D1A RET ARHGEF25 CLIP1 OPHN1 ITPKA MYO3A SLITRK2 ZPR1 SIPA1L1 PJVK RTCA LRP4 SEMA6A CTNND2	6.09e-05	1285	161	24	GO:0031175
GeneOntologyBiologicalProcess	dendrite development	KLHL1 MAP1A WNT7A PAK4 MPDZ CC2D1A CLIP1 ITPKA SIPA1L1 LRP4 CTNND2	6.73e-05	335	161	11	GO:0016358
GeneOntologyBiologicalProcess	microtubule-based process	DNAH3 MAP1A WEE1 DCTN2 IFT172 ASH1L KIF12 CC2D1A CLIP1 NEK2 KIF9 ABRAXAS1 ZPR1 DNAH17 TPPP3 EML1 KIF13A RAB1A DNAH6 DCTN3 DNAH11	7.88e-05	1058	161	21	GO:0007017
GeneOntologyCellularComponent	microtubule associated complex	DNAH3 MAP1A DCTN2 KIF12 KIF9 DNAH17 EML1 KIF13A DNAH6 DCTN3 DNAH11	4.95e-08	161	161	11	GO:0005875
GeneOntologyCellularComponent	somatodendritic compartment	CACNA1D ERBB4 KLHL1 MAP1A ANKS1B MPDZ ZNF385A RET SLC1A4 GPR179 OPHN1 ITPKA PALS1 SNX14 SLITRK2 ZPR1 SIPA1L1 PJVK CNTNAP4 LRP4 MAST1 GNA12 GNAQ CTNND2 RAB1A NOS1 PMM2	7.54e-07	1228	161	27	GO:0036477
GeneOntologyCellularComponent	dendrite	CACNA1D ERBB4 KLHL1 MAP1A ANKS1B MPDZ ZNF385A RET SLC1A4 GPR179 OPHN1 ITPKA SNX14 SLITRK2 SIPA1L1 CNTNAP4 LRP4 MAST1 GNAQ CTNND2 NOS1	2.85e-06	858	161	21	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNA1D ERBB4 KLHL1 MAP1A ANKS1B MPDZ ZNF385A RET SLC1A4 GPR179 OPHN1 ITPKA SNX14 SLITRK2 SIPA1L1 CNTNAP4 LRP4 MAST1 GNAQ CTNND2 NOS1	2.96e-06	860	161	21	GO:0097447
GeneOntologyCellularComponent	microtubule	DNAH3 MAP1A DCTN2 EML6 KIF12 CLIP1 NEK2 KIF9 SYNJ2 DNAH17 TPPP3 EML1 KIF13A DNAH6 DCTN3 DNAH11	3.83e-06	533	161	16	GO:0005874
GeneOntologyCellularComponent	dynein complex	DNAH3 DCTN2 DNAH17 DNAH6 DNAH11	5.94e-05	54	161	5	GO:0030286
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	DNAH3 MAP1A DCTN2 EML6 KIF12 CLIP1 SLC1A4 KPTN NEK2 MYO3A KIF9 SYNJ2 DNAH17 TPPP3 EML1 KIF13A DNAH6 DCTN3 DNAH11	6.57e-05	899	161	19	GO:0099513
GeneOntologyCellularComponent	cell body	CACNA1D ERBB4 KLHL1 MAP1A ZNF385A RET SLC1A4 PALS1 ZPR1 SIPA1L1 PJVK LRP4 MAST1 GNA12 SLC2A13 GNAQ CTNND2 RAB1A PMM2	1.01e-04	929	161	19	GO:0044297
GeneOntologyCellularComponent	supramolecular fiber	CACNA1D DNAH3 MAP1A DCTN2 EML6 KIF12 ARHGEF25 CLIP1 SLC1A4 KPTN NEK2 MYO3A KIF9 SYNJ2 DNAH17 TPPP3 EML1 KIF13A DNAH6 NOS1 DCTN3 DNAH11	1.06e-04	1179	161	22	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	CACNA1D DNAH3 MAP1A DCTN2 EML6 KIF12 ARHGEF25 CLIP1 SLC1A4 KPTN NEK2 MYO3A KIF9 SYNJ2 DNAH17 TPPP3 EML1 KIF13A DNAH6 NOS1 DCTN3 DNAH11	1.17e-04	1187	161	22	GO:0099081
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNA13 GNA11 GNA12 GNAQ	1.47e-04	35	161	4	GO:0005834
GeneOntologyCellularComponent	neuronal cell body	CACNA1D ERBB4 KLHL1 MAP1A ZNF385A RET SLC1A4 PALS1 ZPR1 SIPA1L1 PJVK LRP4 MAST1 GNA12 CTNND2 RAB1A PMM2	2.52e-04	835	161	17	GO:0043025
GeneOntologyCellularComponent	microtubule organizing center	DCTN2 IFT172 RPS7 ANKS1B KIF12 CC2D1A BBS5 NUDCD2 CLIP1 SLC1A4 NEK1 NEK2 CCDC15 AGBL2 KIF13A WDR13 TOP2A DCTN3	2.64e-04	919	161	18	GO:0005815
GeneOntologyCellularComponent	GTPase complex	GNA13 GNA11 GNA12 GNAQ	2.75e-04	41	161	4	GO:1905360
GeneOntologyCellularComponent	primary dendrite	CACNA1D MAP1A	3.50e-04	4	161	2	GO:0150001
GeneOntologyCellularComponent	postsynapse	ERBB4 MAP1A PSMA7 RPS7 ANKS1B MPDZ GPR179 OPHN1 ITPKA KPTN SNX14 SLITRK2 GNA13 SIPA1L1 LRP4 CTNND2 PCBP1 NOS1	8.78e-04	1018	161	18	GO:0098794
GeneOntologyCellularComponent	axonemal dynein complex	DNAH3 DNAH17 DNAH6	9.11e-04	25	161	3	GO:0005858
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	GNA13 GNA11 GNA12 GNAQ	9.12e-04	56	161	4	GO:0031234
GeneOntologyCellularComponent	dynactin complex	DCTN2 DCTN3	1.60e-03	8	161	2	GO:0005869
GeneOntologyCellularComponent	stereocilium	KPTN MYO3A LOXHD1 PJVK	1.99e-03	69	161	4	GO:0032420
GeneOntologyCellularComponent	inner dynein arm	DNAH3 DNAH6	2.55e-03	10	161	2	GO:0036156
GeneOntologyCellularComponent	centrosome	DCTN2 RPS7 ANKS1B CC2D1A BBS5 NUDCD2 CLIP1 SLC1A4 NEK1 NEK2 CCDC15 KIF13A WDR13 DCTN3	2.58e-03	770	161	14	GO:0005813
Domain	P-loop_NTPase	RERG DNAH3 KIF12 PAPSS1 RABL3 PALS1 MYO3A KIF9 RAB9A ARL10 GSPT2 GIMAP8 FBH1 UTP25 CLPB N4BP2 GNA13 DDX54 HS3ST6 RAB40C DDX23 GNA11 GNA12 RAB40B GNAQ KIF13A HS3ST2 RAB1A DNAH6 DNAH11	1.58e-11	848	156	30	IPR027417
Domain	-	RERG DNAH3 PAPSS1 RABL3 PALS1 RAB9A ARL10 GSPT2 GIMAP8 FBH1 UTP25 CLPB N4BP2 GNA13 DDX54 HS3ST6 RAB40C DDX23 GNA11 GNA12 RAB40B GNAQ HS3ST2 RAB1A DNAH6 DNAH11	5.93e-10	746	156	26	3.40.50.300
Domain	Pkinase	RIPK1 WEE1 STK26 PAK4 HUNK WNK1 MELK NEK1 NEK2 MYO3A GUCY2F MAST1 AKT2 WNK2 MAST3	7.42e-07	381	156	15	PF00069
Domain	Prot_kinase_dom	ERBB4 RIPK1 WEE1 STK26 PAK4 HUNK RET WNK1 MELK NEK1 NEK2 MYO3A GUCY2F MAST1 AKT2 WNK2 MAST3	7.42e-07	489	156	17	IPR000719
Domain	PROTEIN_KINASE_DOM	ERBB4 RIPK1 WEE1 STK26 PAK4 HUNK RET WNK1 MELK NEK1 NEK2 MYO3A GUCY2F MAST1 AKT2 WNK2 MAST3	8.30e-07	493	156	17	PS50011
Domain	S_TKc	RIPK1 WEE1 STK26 PAK4 HUNK WNK1 MELK NEK1 NEK2 MYO3A MAST1 AKT2 WNK2 MAST3	1.97e-06	359	156	14	SM00220
Domain	PROTEIN_KINASE_ST	RIPK1 WEE1 STK26 PAK4 HUNK WNK1 MELK NEK1 NEK2 MYO3A MAST1 AKT2 WNK2 MAST3	2.18e-06	362	156	14	PS00108
Domain	Kinase-like_dom	ERBB4 RIPK1 WEE1 STK26 PAK4 HUNK RET WNK1 MELK NEK1 NEK2 MYO3A GUCY2F MAST1 AKT2 WNK2 MAST3	3.00e-06	542	156	17	IPR011009
Domain	PROTEIN_KINASE_ATP	ERBB4 WEE1 STK26 PAK4 HUNK RET WNK1 MELK NEK1 NEK2 MYO3A MAST1 AKT2 WNK2 MAST3	7.28e-06	459	156	15	PS00107
Domain	GproteinA_insert	GNA13 GNA11 GNA12 GNAQ	7.88e-06	16	156	4	IPR011025
Domain	-	GNA13 GNA11 GNA12 GNAQ	7.88e-06	16	156	4	1.10.400.10
Domain	G-alpha	GNA13 GNA11 GNA12 GNAQ	7.88e-06	16	156	4	PF00503
Domain	G_alpha	GNA13 GNA11 GNA12 GNAQ	7.88e-06	16	156	4	SM00275
Domain	Ser/Thr_kinase_AS	RIPK1 WEE1 PAK4 HUNK WNK1 MELK NEK1 NEK2 MYO3A MAST1 AKT2 WNK2 MAST3	9.74e-06	357	156	13	IPR008271
Domain	Gprotein_alpha_su	GNA13 GNA11 GNA12 GNAQ	1.02e-05	17	156	4	IPR001019
Domain	CXorf40	EOLA1 EOLA2	6.93e-05	2	156	2	IPR033615
Domain	Gprotein_alpha_12/13	GNA13 GNA12	6.93e-05	2	156	2	IPR000469
Domain	PDZ	MPDZ PALS1 SIPA1L1 MAST1 PDZD8 NOS1 MAST3	1.84e-04	141	156	7	PF00595
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	IPR013602
Domain	DHC_N2	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	IPR011704
Domain	MT	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	PF12777
Domain	AAA_8	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	PF12780
Domain	AAA_5	DNAH3 DNAH6 DNAH11	1.94e-04	14	156	3	PF07728
Domain	ASCH_domain	EOLA1 EOLA2	2.07e-04	3	156	2	IPR007374
Domain	ASCH	EOLA1 EOLA2	2.07e-04	3	156	2	SM01022
Domain	DHC_fam	DNAH3 DNAH6 DNAH11	2.42e-04	15	156	3	IPR026983
Domain	Dynein_heavy	DNAH3 DNAH6 DNAH11	2.42e-04	15	156	3	PF03028
Domain	Dynein_heavy_dom	DNAH3 DNAH6 DNAH11	2.42e-04	15	156	3	IPR004273
Domain	PDZ	MPDZ PALS1 SIPA1L1 MAST1 PDZD8 NOS1 MAST3	2.48e-04	148	156	7	SM00228
Domain	-	MPDZ PALS1 SIPA1L1 MAST1 PDZD8 NOS1 MAST3	2.69e-04	150	156	7	2.30.42.10
Domain	PDZ	MPDZ PALS1 SIPA1L1 MAST1 PDZD8 NOS1 MAST3	2.80e-04	151	156	7	PS50106
Domain	PDZ	MPDZ PALS1 SIPA1L1 MAST1 PDZD8 NOS1 MAST3	2.91e-04	152	156	7	IPR001478
Domain	RAB	RABL3 RAB9A RAB40C RAB40B RAB1A	3.62e-04	73	156	5	PS51419
Domain	Small_GTPase	RERG RABL3 RAB9A ARL10 RAB40C RAB40B RAB1A	3.98e-04	160	156	7	IPR001806
Domain	DUF1908	MAST1 MAST3	4.11e-04	4	156	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST1 MAST3	4.11e-04	4	156	2	IPR015022
Domain	Gprotein_alpha_Q	GNA11 GNAQ	4.11e-04	4	156	2	IPR000654
Domain	MAST_pre-PK_dom	MAST1 MAST3	4.11e-04	4	156	2	IPR023142
Domain	-	MAST1 MAST3	4.11e-04	4	156	2	1.20.1480.20
Domain	PUA-like_domain	EOLA1 PAPSS1 EOLA2	5.02e-04	19	156	3	IPR015947
Domain	Quino_amine_DH_bsu	TRIM2 NBAS EML1	7.83e-04	22	156	3	IPR011044
Domain	Ras	RERG RABL3 RAB9A RAB40C RAB40B RAB1A	9.93e-04	136	156	6	PF00071
Domain	OSR1_C	WNK1 WNK2	1.02e-03	6	156	2	PF12202
Domain	HELP	EML6 EML1	1.02e-03	6	156	2	PF03451
Domain	Kinase_OSR1/WNK_CCT	WNK1 WNK2	1.02e-03	6	156	2	IPR024678
Domain	HELP	EML6 EML1	1.02e-03	6	156	2	IPR005108
Domain	Protein_kinase_ATP_BS	ERBB4 WEE1 STK26 PAK4 HUNK RET MELK NEK1 MYO3A AKT2	1.34e-03	379	156	10	IPR017441
Domain	IPK	ITPKA ITPKB	1.42e-03	7	156	2	PF03770
Domain	IPK	ITPKA ITPKB	1.42e-03	7	156	2	IPR005522
Domain	NHL_repeat_subgr	TRIM2 TRIM71	2.40e-03	9	156	2	IPR013017
Domain	Small_GTP-bd_dom	RERG RAB9A ARL10 RAB40C RAB40B RAB1A	2.82e-03	167	156	6	IPR005225
Domain	IG_FLMN	TRIM2 TRIM71	2.99e-03	10	156	2	SM00557
Domain	NHL_repeat	TRIM2 TRIM71	2.99e-03	10	156	2	IPR001258
Domain	NHL	TRIM2 TRIM71	2.99e-03	10	156	2	PF01436
Domain	Filamin	TRIM2 TRIM71	3.63e-03	11	156	2	PF00630
Domain	BAH	ASH1L BAHCC1	3.63e-03	11	156	2	PS51038
Domain	FILAMIN_REPEAT	TRIM2 TRIM71	3.63e-03	11	156	2	PS50194
Domain	Filamin/ABP280_rpt	TRIM2 TRIM71	3.63e-03	11	156	2	IPR001298
Domain	Filamin/ABP280_repeat-like	TRIM2 TRIM71	3.63e-03	11	156	2	IPR017868
Domain	BAH_dom	ASH1L BAHCC1	3.63e-03	11	156	2	IPR001025
Domain	BAH	ASH1L BAHCC1	3.63e-03	11	156	2	SM00439
Domain	BAH	ASH1L BAHCC1	3.63e-03	11	156	2	PF01426
Domain	-	TRIM2 TRIM71 LRP4	4.19e-03	39	156	3	2.120.10.30
Domain	SET	SMYD1 KMT5A ASH1L	4.83e-03	41	156	3	PF00856
Domain	Kinesin_motor_CS	KIF12 KIF9 KIF13A	4.83e-03	41	156	3	IPR019821
Domain	L27	MPDZ PALS1	5.09e-03	13	156	2	SM00569
Domain	L27	MPDZ PALS1	5.09e-03	13	156	2	PS51022
Domain	L27_dom	MPDZ PALS1	5.09e-03	13	156	2	IPR004172
Domain	NHL	TRIM2 TRIM71	5.09e-03	13	156	2	PS51125
Domain	Pkinase_C	MAST1 AKT2 MAST3	5.17e-03	42	156	3	PF00433
Domain	Kinesin-like_fam	KIF12 KIF9 KIF13A	5.52e-03	43	156	3	IPR027640
Domain	-	KIF12 KIF9 KIF13A	5.89e-03	44	156	3	3.40.850.10
Domain	Kinesin	KIF12 KIF9 KIF13A	5.89e-03	44	156	3	PF00225
Domain	KISc	KIF12 KIF9 KIF13A	5.89e-03	44	156	3	SM00129
Domain	KINESIN_MOTOR_1	KIF12 KIF9 KIF13A	5.89e-03	44	156	3	PS00411
Domain	Kinesin_motor_dom	KIF12 KIF9 KIF13A	5.89e-03	44	156	3	IPR001752
Domain	KINESIN_MOTOR_2	KIF12 KIF9 KIF13A	5.89e-03	44	156	3	PS50067
Domain	SET	SMYD1 KMT5A ASH1L	6.67e-03	46	156	3	SM00317
Domain	6-blade_b-propeller_TolB-like	TRIM2 TRIM71 LRP4	6.67e-03	46	156	3	IPR011042
Domain	PSI	PLXNA3 SEMA6A SLC2A13	6.67e-03	46	156	3	SM00423
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH3 DCTN2 DNAH17 DNAH6 DCTN3 DNAH11	1.09e-07	27	125	6	M47755
Pathway	PID_S1P_META_PATHWAY	S1PR3 GNA13 GNA11 GNA12 GNAQ	9.19e-07	21	125	5	M155
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	DNAH3 DCTN2 DNAH17 DNAH6 DCTN3 DNAH11	2.01e-06	43	125	6	M47669
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH3 DCTN2 DNAH17 DNAH6 DCTN3 DNAH11	2.64e-06	45	125	6	M47670
Pathway	PID_S1P_S1P3_PATHWAY	S1PR3 GNA13 GNA11 GNA12 GNAQ	5.07e-06	29	125	5	M55
Pathway	BIOCARTA_LIS1_PATHWAY	DNAH3 CLIP1 DNAH6 DCTN3	2.06e-05	19	125	4	M22005
Pathway	PID_S1P_S1P2_PATHWAY	GNA13 GNA11 GNA12 GNAQ	5.46e-05	24	125	4	M268
Pathway	BIOCARTA_MYOSIN_PATHWAY	GNA13 GNA12 GNAQ	1.07e-04	11	125	3	M7014
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNA13 GNA11 GNA12 GNAQ	1.75e-04	32	125	4	M861
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNA13 GNA11 GNA12 GNAQ	1.75e-04	32	125	4	MM15148
Pathway	PID_THROMBIN_PAR4_PATHWAY	GNA13 GNA11 GNAQ	2.86e-04	15	125	3	M138
Pubmed	Galpha12/13 is essential for directed cell migration and localized Rho-Dia1 function.	GNA13 GNA11 GNA12 GNAQ	4.54e-10	4	162	4	16251183
Pubmed	Antagonistic regulation of neurite morphology through Gq/G11 and G12/G13.	GNA13 GNA11 GNA12 GNAQ	4.54e-10	4	162	4	18854320
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAP1A DCTN2 PPFIA4 STK26 PSMA7 RPS7 ANKS1B PFKL SLC1A4 OPHN1 ITPKA ITPKB PARP1 TKT SIPA1L1 MAST1 GNAQ UQCRC2 CTNND2 RAB1A PCBP1 DNAH6 NOS1 MOG WNK2 SEC23A DNAH11	6.05e-10	1431	162	27	37142655
Pubmed	G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure.	GNA13 GNA11 GNA12 GNAQ	2.26e-09	5	162	4	22972902
Pubmed	Myogenic vasoconstriction requires G12/G13 and LARG to maintain local and systemic vascular resistance.	GNA13 GNA11 GNA12 GNAQ	2.26e-09	5	162	4	31549965
Pubmed	Anaphylactic shock depends on endothelial Gq/G11.	GNA13 GNA11 GNA12 GNAQ	2.26e-09	5	162	4	19171764
Pubmed	G protein-dependent basal and evoked endothelial cell vWF secretion.	GNA13 GNA11 GNA12 GNAQ	2.26e-09	5	162	4	24081657
Pubmed	Procontractile G protein-mediated signaling pathways antagonistically regulate smooth muscle differentiation in vascular remodeling.	GNA13 GNA11 GNA12 GNAQ	2.26e-09	5	162	4	23129751
Pubmed	Translating biased signaling in the ghrelin receptor system into differential in vivo functions.	GNA13 GNA11 GNA12 GNAQ	2.26e-09	5	162	4	30301804
Pubmed	Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33-mediated macrophage polarization and emphysema.	GNA13 GNA11 GNA12 GNAQ	6.75e-09	6	162	4	27811142
Pubmed	G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension.	GNA13 GNA11 GNA12 GNAQ	6.75e-09	6	162	4	18084302
Pubmed	Lysophospholipids control integrin-dependent adhesion in splenic B cells through G(i) and G(12)/G(13) family G-proteins but not through G(q)/G(11).	GNA13 GNA11 GNA12 GNAQ	1.57e-08	7	162	4	17023430
Pubmed	Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach.	GNA13 GNA11 GNA12 GNAQ	9.32e-08	10	162	4	8588930
Pubmed	The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families.	GNA13 GNA11 GNA12 GNAQ	9.32e-08	10	162	4	8552586
Pubmed	Expression of GTP-binding protein alpha subunits in human thymocytes.	GNA13 GNA12 GNAQ	9.92e-08	3	162	3	7791744
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CDCA3 DCTN2 PSMA7 PAK4 MPDZ NBN CC2D1A DBT RABL3 NBAS PARP1 CLPB N4BP2 DDX54 ZRANB2 DDX23 PDZD8 AKT2 SEMA6A UQCRC2 FAR1 ALDH9A1 MRPL9 MAST3	1.15e-07	1487	162	24	33957083
Pubmed	Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.	GNA13 GNA11 GNA12 GNAQ	1.46e-07	11	162	4	32332099
Pubmed	Age-dependent blood pressure elevation is due to increased vascular smooth muscle tone mediated by G-protein signalling.	GNA13 GNA11 GNA12 GNAQ	3.14e-07	13	162	4	26531127
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	DCTN2 STK26 RPS7 TTC27 PNO1 OR2T1 PFKL DBT NUDCD2 PAPSS1 PALS1 PARP1 NUDT4 GSPT2 SIPA1L1 DDX54 GNA11 RAB1A PCBP1 TOP2A DCTN3	3.88e-07	1247	162	21	27684187
Pubmed	Activation of Galpha (i) and subsequent uncoupling of receptor-Galpha(i) signaling by Pasteurella multocida toxin.	GNA13 GNA11 GNA12	3.95e-07	4	162	3	18583341
Pubmed	RGS22, a novel testis-specific regulator of G-protein signaling involved in human and mouse spermiogenesis along with GNA12/13 subunits.	GNA13 GNA11 GNA12	3.95e-07	4	162	3	18703424
Pubmed	N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias.	GNA13 GNA11 GNA12	3.95e-07	4	162	3	26100877
Pubmed	Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways.	GNA13 GNA12 GNAQ	3.95e-07	4	162	3	12077299
Pubmed	Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis.	ARHGEF25 GNA11 GNAQ	3.95e-07	4	162	3	23696743
Pubmed	Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets.	GNA13 GNA12 GNAQ	3.95e-07	4	162	3	10037795
Pubmed	Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.	GNA13 GNA12 GNAQ	3.95e-07	4	162	3	12771155
Pubmed	Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency.	GNA13 GNA12 GNAQ	3.95e-07	4	162	3	8999798
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH17 DNAH6 DNAH11	4.38e-07	14	162	4	9373155
Pubmed	Mechanism of GTP hydrolysis by G-protein alpha subunits.	GNA13 GNA11 GNA12 GNAQ	5.95e-07	15	162	4	7937899
Pubmed	RNA binding proteins co-localize with small tau inclusions in tauopathy.	DCTN2 PFKL TKT ZRANB2 GNA11 GNAQ RAB1A PCBP1 MOG DCTN3	9.47e-07	283	162	10	30068389
Pubmed	Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.	S1PR3 GNA11 GNAQ	9.85e-07	5	162	3	25832730
Pubmed	Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn kinase.	GNA13 GNA12 GNAQ	9.85e-07	5	162	3	21592972
Pubmed	Assembly of high order G alpha q-effector complexes with RGS proteins.	ARHGEF25 GNA11 GNAQ	9.85e-07	5	162	3	18936096
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MAP1A PFKL SLC1A4 GNA13 SIPA1L1 ZRANB2 GNA11 GNA12 GNAQ UQCRC2 RAB1A NOS1 MOG SEC23A	1.42e-06	621	162	14	22794259
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PSMA7 RPS7 TTC27 PNO1 PFKL IFI16 MELK BLVRA PARP1 TKT RTCA DDX54 DDX23 UQCRC2 FAR1 ALDH9A1 PCBP1 WDR13 TOP2A SEC23A PMM2	1.43e-06	1353	162	21	29467282
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KBTBD3 UXS1 TRIM26 KAT6A ASH1L TP53I11 LAMA3 LMBR1 ZNF385A PFKL STEAP2 PCDHB16 ANO8 ITPKB SYNJ2 EEPD1 DIP2C MAST1 SEMA6A RAB40B WDR13 WNK2	1.76e-06	1489	162	22	28611215
Pubmed	Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins.	S1PR3 GNA13 GNAQ	1.96e-06	6	162	3	10488065
Pubmed	NIMA-related kinases: isolation and characterization of murine nek3 and nek4 cDNAs, and chromosomal localization of nek1, nek2 and nek3.	NEK1 PARP1 NEK2	1.96e-06	6	162	3	10393247
Pubmed	Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q.	GNA13 GNA11 GNA12	1.96e-06	6	162	3	18713748
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SYNJ2 SIPA1L1 CNTNAP4 LRP4 SEMA6A MAST3 BAHCC1	2.73e-06	130	162	7	12421765
Pubmed	RGS16 inhibits signalling through the G alpha 13-Rho axis.	GNA13 GNA12 GNAQ	3.42e-06	7	162	3	14634662
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PLXNA3 PCDHGA6 PPFIA4 PSMA7 RPS7 EML6 ASH1L ANKS1B PARP1 NEK2 GSPT2 TKT N4BP2 GNA13 DDX23 GNA12 UQCRC2 RAB1A DNAH6 TOP2A BAHCC1	3.87e-06	1442	162	21	35575683
Pubmed	Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices.	GNA13 GNA11 GNA12	8.16e-06	9	162	3	18086886
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNA13 GNA11 GNA12 GNAQ	8.51e-06	28	162	4	8858601
Pubmed	Characteristic defects in neural crest cell-specific Galphaq/Galpha11- and Galpha12/Galpha13-deficient mice.	GNA13 GNA11 GNAQ	2.12e-05	12	162	3	15936338
Pubmed	Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse.	GNA13 GNA11 GNA12	2.12e-05	12	162	3	2508088
Pubmed	The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.	GNA11 GNAQ	2.16e-05	2	162	2	28248732
Pubmed	Activation of Gq/11 in the mouse corpus luteum is required for parturition.	GNA11 GNAQ	2.16e-05	2	162	2	25495873
Pubmed	Selective activation of human atrial Galpha12 and Galpha13 by Galphaq-coupled angiotensin and endothelin receptors.	GNA13 GNA12	2.16e-05	2	162	2	17878759
Pubmed	Localization of the genes for human inositol 1,4,5-trisphosphate 3-kinase A (ITPKA) and B (ITPKB) to chromosome regions 15q14-q21 and 1q41-q43, respectively, by in situ hybridization.	ITPKA ITPKB	2.16e-05	2	162	2	1330886
Pubmed	Molecular genetic testing of uveal melanoma from routinely processed and stained cytology specimens.	GNA11 GNAQ	2.16e-05	2	162	2	21945171
Pubmed	Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association.	GNA11 GNAQ	2.16e-05	2	162	2	9175863
Pubmed	G13 is an essential mediator of platelet activation in hemostasis and thrombosis.	GNA13 GNA12	2.16e-05	2	162	2	14528298
Pubmed	N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors.	GNA13 GNA12	2.16e-05	2	162	2	12594220
Pubmed	The ethnic profile of patients with birthmarks reveals interaction of germline and postzygotic genetics.	GNA11 GNAQ	2.16e-05	2	162	2	28083870
Pubmed	Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location.	ARHGEF25 GNAQ	2.16e-05	2	162	2	23884432
Pubmed	Gq/11-Dependent Changes in the Murine Ovarian Transcriptome at the End of Gestation.	GNA11 GNAQ	2.16e-05	2	162	2	26843449
Pubmed	Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.	GNA11 GNAQ	2.16e-05	2	162	2	30890659
Pubmed	nNOS in Erbb4-positive neurons regulates GABAergic transmission in mouse hippocampus.	ERBB4 NOS1	2.16e-05	2	162	2	38396027
Pubmed	TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma.	PARP1 TKT	2.16e-05	2	162	2	38216672
Pubmed	Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system.	NEK1 NEK2	2.16e-05	2	162	2	9583679
Pubmed	Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.	STK26 PAK4	2.16e-05	2	162	2	24374310
Pubmed	KAT6A Condensates Impair PARP1 Trapping of PARP Inhibitors in Ovarian Cancer.	KAT6A PARP1	2.16e-05	2	162	2	38973255
Pubmed	Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.	GNA11 GNAQ	2.16e-05	2	162	2	9607776
Pubmed	The arm-repeat protein NPRAP (neurojungin) is a constituent of the plaques of the outer limiting zone in the retina, defining a novel type of adhering junction.	CTNND2 SYMPK	2.16e-05	2	162	2	10413599
Pubmed	Reverse Phenotyping in Patients with Skin Capillary Malformations and Mosaic GNAQ or GNA11 Mutations Defines a Clinical Spectrum with Genotype-Phenotype Correlation.	GNA11 GNAQ	2.16e-05	2	162	2	31726051
Pubmed	G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region.	GNA11 GNAQ	2.16e-05	2	162	2	11438569
Pubmed	GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.	GNA11 GNAQ	2.16e-05	2	162	2	37802294
Pubmed	Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors.	GNA11 GNAQ	2.16e-05	2	162	2	26628681
Pubmed	The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA.	ARHGEF25 GNA11	2.16e-05	2	162	2	15632174
Pubmed	The time-course of agonist-induced solubilization of trimeric G(q)alpha/G(11)alpha proteins resolved by two-dimensional electrophoresis.	GNA11 GNAQ	2.16e-05	2	162	2	17552882
Pubmed	Molecular cloning and expression of a new putative inositol 1,4,5-trisphosphate 3-kinase isoenzyme.	ITPKA ITPKB	2.16e-05	2	162	2	1654894
Pubmed	Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.	GNA11 GNAQ	2.16e-05	2	162	2	31173078
Pubmed	Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.	GNA11 GNAQ	2.16e-05	2	162	2	29209985
Pubmed	The TIMELESS and PARP1 interaction suppresses replication-associated DNA gap accumulation.	PARP1 TIMELESS	2.16e-05	2	162	2	38801073
Pubmed	Galpha12 and Galpha13 mediate differentiation of P19 mouse embryonal carcinoma cells in response to retinoic acid.	GNA13 GNA12	2.16e-05	2	162	2	9305907
Pubmed	Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior.	GNA11 GNAQ	2.16e-05	2	162	2	15175381
Pubmed	WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia.	WNK1 WNK2	2.16e-05	2	162	2	35849656
Pubmed	Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.	GNA11 GNAQ	2.16e-05	2	162	2	25280020
Pubmed	GNAQ and GNA11 mutations occur in 9.5% of mucosal melanoma and are associated with poor prognosis.	GNA11 GNAQ	2.16e-05	2	162	2	27498141
Pubmed	Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.	GNA13 GNA12	2.16e-05	2	162	2	11976333
Pubmed	Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin.	GNA13 GNA12	2.16e-05	2	162	2	24590762
Pubmed	G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits.	GNA13 GNA12	2.16e-05	2	162	2	1905812
Pubmed	Uveal Melanoma: GNAQ and GNA11 Mutations in a Greek Population.	GNA11 GNAQ	2.16e-05	2	162	2	28982892
Pubmed	Mutations in GNA11 in uveal melanoma.	GNA11 GNAQ	2.16e-05	2	162	2	21083380
Pubmed	GNAQ and GNA11 mutations in uveal melanoma.	GNA11 GNAQ	2.16e-05	2	162	2	25304237
Pubmed	Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.	GNA11 GNAQ	2.16e-05	2	162	2	28301547
Pubmed	Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.	GNA11 GNAQ	2.16e-05	2	162	2	16847339
Pubmed	Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology.	GNA11 GNAQ	2.16e-05	2	162	2	29570931
Pubmed	Muscarinic inhibition of calcium current and M current in Galpha q-deficient mice.	GNA11 GNAQ	2.16e-05	2	162	2	10818132
Pubmed	Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis.	GNA11 GNAQ	2.16e-05	2	162	2	26272756
Pubmed	NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.	GNA11 GNAQ	2.16e-05	2	162	2	31461351
Pubmed	Role of G12 proteins in oncogenesis and metastasis.	GNA13 GNA12	2.16e-05	2	162	2	19422395
Pubmed	Ultradeep sequencing detects GNAQ and GNA11 mutations in cell-free DNA from plasma of patients with uveal melanoma.	GNA11 GNAQ	2.16e-05	2	162	2	23634288
Pubmed	Distribution of GNAQ and GNA11 Mutation Signatures in Uveal Melanoma Points to a Light Dependent Mutation Mechanism.	GNA11 GNAQ	2.16e-05	2	162	2	26368812
Pubmed	Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to cholecystokinin are mediated by a transient receptor potential-like current.	GNA11 GNAQ	2.16e-05	2	162	2	17482476
Pubmed	Kinase-independent role of nuclear RIPK1 in regulating parthanatos through physical interaction with PARP1 upon oxidative stress.	RIPK1 PARP1	2.16e-05	2	162	2	28993228
Pubmed	Regulation of RhoGEF proteins by G12/13-coupled receptors.	GNA13 GNA12	2.16e-05	2	162	2	19226283
Pubmed	Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.	GNA11 GNAQ	2.16e-05	2	162	2	24141786
Pubmed	PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis.	RIPK1 PARP1	2.16e-05	2	162	2	21460625
Interaction	RIC8A interactions	DCTN2 PARP1 GNA13 GNA11 GNA12 SLC2A13 GNAQ DCTN3	8.83e-07	96	158	8	int:RIC8A
Interaction	KCTD13 interactions	MAP1A DCTN2 PPFIA4 STK26 PSMA7 RPS7 ANKS1B PFKL SLC1A4 OPHN1 ITPKA ITPKB PARP1 TKT SIPA1L1 MAST1 GNAQ UQCRC2 CTNND2 RAB1A PCBP1 DNAH6 NOS1 MOG WNK2 SEC23A DNAH11	1.10e-05	1394	158	27	int:KCTD13
Interaction	S1PR3 interactions	S1PR3 GNA13 GNAQ	1.62e-05	7	158	3	int:S1PR3
GeneFamily	Dyneins, axonemal	DNAH3 DNAH17 DNAH6 DNAH11	3.01e-06	17	111	4	536
GeneFamily	PDZ domain containing	MPDZ PALS1 SIPA1L1 MAST1 PDZD8 NOS1 MAST3	4.23e-05	152	111	7	1220
GeneFamily	Dynactin	DCTN2 DCTN3	5.51e-04	6	111	2	943
GeneFamily	RAB, member RAS oncogene GTPases	RAB9A RAB40C RAB40B RAB1A	6.83e-04	65	111	4	388
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SMYD1 KMT5A ASH1L	1.17e-03	34	111	3	487
GeneFamily	PDZ domain containing\|Crumbs complex	MPDZ PALS1	1.31e-03	9	111	2	1223
GeneFamily	Low density lipoprotein receptors	LRP12 LRP4	2.79e-03	13	111	2	634
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF12 KIF9 KIF13A	2.82e-03	46	111	3	622
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP1 ZPR1	3.72e-03	15	111	2	26
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	CDCA3 WEE1 PNO1 NBN NUDCD2 STEAP2 MELK SLC1A4 PALS1 PARP1 NEK2 LOXHD1 NUDT4 TKT N4BP2 ZPR1 SIPA1L1 DENND2C RTCA DDX54 TIMELESS UQCRC2 FAR1 RAB1A PCBP1 TOP2A	1.02e-07	1290	162	26	M80
Coexpression	PEREZ_TP53_TARGETS	EVC2 TRIM2 WEE1 TRIM26 WNT7A EML6 ASH1L TP53I11 TRIM71 ZNF385A HUNK S1PR3 ITPKB KIF9 DENND2C RTCA DIP2C HS3ST6 GNA11 EML1 ATG4D	1.72e-05	1201	162	21	M4391
Coexpression	FAN_EMBRYONIC_CTX_OLIG	KBTBD3 TRIM2 MAP1A AGPAT4 ANKS1B WNK1 PAPSS1 ITPKB RAB9A SYNJ2 DNAH17 RAB40B FAR1 KIF13A MOG MAST3	1.90e-05	754	162	16	M39037
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2A	WNT7A MPDZ SLC1A4 OPHN1 PALS1 KIF9 SLITRK2 RAB9A EEPD1 SNX31 SEMA6A CTNND2 ALDH9A1 DNAH6	2.31e-05	600	162	14	M39055
Coexpression	CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP	PLXNA3 CACNA1D ASH1L SLC35A1 KIF12 SLC1A4 NUDT4 CSRNP2 DIP2C RAB40C CTNND2	2.94e-05	385	162	11	M2840
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN	EOLA1 PNO1 PFKL PAPSS1 RABL3 NUDT4 ATG4D DCTN3	3.49e-05	199	162	8	M4025
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK3 CDCA3 ERBB4 LAMA3 MELK NEK2 MYO3A CTNND2 TOP2A	3.58e-08	191	162	9	39220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 CACNA1D ERBB4 TRIM2 WNK1 ITPKB NUDT4 NOS1	4.75e-07	189	162	8	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	ILEUM-non-inflamed-(8)_Activated_fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CDCA3 MAP1A MPDZ NEK2 MAST1 GNA11 EML1 KIF13A	4.95e-07	190	162	8	39fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT6A ITPKB EEPD1 SEMA6A GNAQ TPPP3 CTNND2 KIF13A	5.57e-07	193	162	8	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT6A ITPKB EEPD1 SEMA6A GNAQ TPPP3 CTNND2 KIF13A	5.57e-07	193	162	8	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM2 AGPAT4 ANKS1B PAPSS1 GNA12 SEMA6A MOG MAST3	7.29e-07	200	162	8	56f1f007ba8c9188a4b10e52744f1e50dc0f155a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ERBB4 TRIM71 WNK1 OPHN1 ITPKB NOS1	2.02e-06	160	162	7	8bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ERBB4 TRIM71 WNK1 OPHN1 ITPKB NOS1	2.02e-06	160	162	7	2d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EOLA1 LAMA3 MELK MYO3A CCDC15 TIMELESS TOP2A	2.48e-06	165	162	7	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB4 ANKS1B RET GPR179 MAST1 HS3ST2 NOS1	3.81e-06	176	162	7	116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB4 ANKS1B RET GPR179 MAST1 HS3ST2 NOS1	3.81e-06	176	162	7	5b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|lymph-node_spleen / Manually curated celltypes from each tissue	TRIM71 MELK NEK2 CCDC15 TPPP3 LYPD8 TOP2A	5.10e-06	184	162	7	f93373fcde5c31f4ffe67ca0f3ea7f4e906dc88b
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT6A EEPD1 SEMA6A GNAQ TPPP3 EML1 KIF13A	5.67e-06	187	162	7	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVC2 RET ARHGEF25 SLC1A4 S1PR3 THBS2 TPPP3	6.08e-06	189	162	7	1db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVC2 RET ARHGEF25 SLC1A4 S1PR3 THBS2 TPPP3	6.08e-06	189	162	7	bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVC2 RET ARHGEF25 SLC1A4 S1PR3 THBS2 TPPP3	6.08e-06	189	162	7	14833feea8f80744a06ece73f813eaeff8c4dd61
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ERBB4 TRIM2 WNK1 ITPKB NUDT4 NOS1	6.29e-06	190	162	7	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	background-Cholangiocytes\|background / Sample and Cell Type and Tumor Cluster (all cells)	ERBB4 KIF12 HUNK SYNJ2 TPPP3 CTNND2 WNK2	6.97e-06	193	162	7	9152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 ERBB4 TRIM2 MPDZ TPPP3 DNAH6 DNAH11	7.46e-06	195	162	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 ERBB4 TRIM2 MPDZ TPPP3 DNAH6 DNAH11	7.46e-06	195	162	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	ASK428-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	RERG EVC2 IFI16 EGFL6 THBS2 EEPD1 SEMA6A	7.46e-06	195	162	7	c750602c765a51075ba6ede78e3ba80b62374481
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 TRIM2 MPDZ TPPP3 DNAH6 TOP2A DNAH11	7.71e-06	196	162	7	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 TRIM2 MPDZ TPPP3 DNAH6 TOP2A DNAH11	7.71e-06	196	162	7	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDCA3 TRIM2 MELK EGFL6 NEK2 CTNND2 TOP2A	7.97e-06	197	162	7	6de02b02fcdfcab1c1b0f4a4c75677410bc55688
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDCA3 KMT5A NUDCD2 MELK NEK2 TIMELESS TOP2A	7.97e-06	197	162	7	a0d463825b62de49466f9fa563405dda4387cfff
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 MELK NEK2 MYO3A DNAH6 TOP2A DNAH11	8.24e-06	198	162	7	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDCA3 WEE1 HUNK MELK NEK2 MYO3A TOP2A	8.24e-06	198	162	7	f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CDCA3 WEE1 KMT5A MELK NEK2 TIMELESS TOP2A	8.24e-06	198	162	7	dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell	(11)_FOXN4+\|World / shred by cell type by condition	MAP1A MELK NEK2 KIF9 TPPP3 EML1 TOP2A	8.24e-06	198	162	7	516b1acdf997dd8debc3dca066519366e507b414
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 SALL4 MELK NEK2 AGBL2 DNAH6 TOP2A	8.51e-06	199	162	7	92778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 MAP1A ANKS1B THBS2 DNAH17 RAB40B TPPP3	8.51e-06	199	162	7	5d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CDCA3 WEE1 KMT5A NUDCD2 MELK NEK2 TOP2A	8.51e-06	199	162	7	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 MAP1A ANKS1B THBS2 DNAH17 RAB40B TPPP3	8.51e-06	199	162	7	9dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM2 AGPAT4 NUDT4 GNA12 TPPP3 MOG MAST3	8.51e-06	199	162	7	67d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 MAP1A ANKS1B THBS2 DNAH17 RAB40B TPPP3	8.51e-06	199	162	7	6fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 MAP1A ANKS1B THBS2 DNAH17 RAB40B TPPP3	8.51e-06	199	162	7	1bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM2 WNK1 PAPSS1 GNA12 SEMA6A EML1 KIF13A	8.79e-06	200	162	7	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM2 AGPAT4 GNA12 SEMA6A EML1 MOG MAST3	8.79e-06	200	162	7	e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SMYD1 TRIM71 GPR179 EGFL6 DNAH6	1.24e-05	82	162	5	89aff8676f98e062d0e69b38c7184e51aa1a915e
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SMYD1 TRIM71 GPR179 EGFL6 DNAH6	1.24e-05	82	162	5	6875a10abf1221b3dfd954c319b5e8e12fac1ff2
ToppCell	Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SMYD1 TRIM71 GPR179 EGFL6 DNAH6	1.24e-05	82	162	5	259bb4ae0373d8352cb1c3bff08f66b89a298440
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 MPDZ MYO3A EEPD1 SEMA6A NOS1	2.00e-05	152	162	6	fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 LAMA3 HUNK RET STEAP2 CNTNAP4	2.57e-05	159	162	6	c64fff8d89f84d1f5a0cc432e31f56f741162505
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK3 ERBB4 ANKS1B GUCY2F TPPP3 WNK2	2.86e-05	162	162	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 WEE1 LAMA3 EEPD1 DNAH6 NOS1	2.86e-05	162	162	6	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RERG MAP1A PCDHGA6 MPDZ CSRNP2 DDX54	2.96e-05	163	162	6	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LRP12 ERBB4 MPDZ EEPD1 SEMA6A NOS1	3.06e-05	164	162	6	08819970174a3eb4eee8e1e675075828665b845e
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RERG ERBB4 ZNF385A HUNK STEAP2 CNTNAP4	3.50e-05	168	162	6	2572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 MELK NEK2 MYO3A TIMELESS TOP2A	3.62e-05	169	162	6	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	droplet-Thymus-nan-18m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 KIF12 EML1 HS3ST2 DNAH6 LYPD8	3.62e-05	169	162	6	4ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D TRIM71 WNK1 OPHN1 ITPKB NOS1	4.13e-05	173	162	6	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 MELK NEK2 CNTNAP4 SEMA6A TOP2A	4.40e-05	175	162	6	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 MELK NEK2 CNTNAP4 SEMA6A TOP2A	4.40e-05	175	162	6	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CDCA3 EML6 SLC1A4 NEK2 DENND2C TOP2A	4.40e-05	175	162	6	89bf89466191da14896ed8928027f5b911436c22
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 MELK NEK2 CNTNAP4 SEMA6A TOP2A	4.40e-05	175	162	6	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDCA3 PPFIA4 BBS5 MELK CTNND2 TOP2A	4.40e-05	175	162	6	73f25bd54309aed1480ddc44bdab518b17e71f92
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDCA3 MELK NEK2 CNTNAP4 SEMA6A TOP2A	4.40e-05	175	162	6	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	NS-critical-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MELK EGFL6 NEK2 EEPD1 EML1 TOP2A	4.54e-05	176	162	6	7cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell	Ciliated_cells-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 MAP1A AGBL2 DNAH6 WNK2 DNAH11	4.84e-05	178	162	6	255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CDCA3 MELK SLC1A4 NEK2 CCDC15 TOP2A	4.84e-05	178	162	6	c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A MELK NEK2 KIF9 TPPP3 TOP2A	4.99e-05	179	162	6	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAP1A MELK NEK2 KIF9 TPPP3 TOP2A	4.99e-05	179	162	6	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDCA3 MELK NEK2 DENND2C TIMELESS TOP2A	4.99e-05	179	162	6	54621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK2 MYO3A KIF9 CCDC15 TPPP3 TOP2A	5.15e-05	180	162	6	0c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK2 MYO3A KIF9 CCDC15 TPPP3 TOP2A	5.15e-05	180	162	6	e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEK2 MYO3A KIF9 CCDC15 TPPP3 TOP2A	5.15e-05	180	162	6	11455ba704ac73f69b474845136cfecec6a88349
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RERG DNAH3 ERBB4 KLHL1 EGFL6 CNTNAP4	5.15e-05	180	162	6	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CDCA3 WEE1 MELK NEK2 AGBL2 TOP2A	5.31e-05	181	162	6	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D TRIM71 WNK1 OPHN1 ITPKB NOS1	5.31e-05	181	162	6	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 WEE1 LAMA3 EEPD1 DNAH6 NOS1	5.47e-05	182	162	6	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RERG ERBB4 TP53I11 LAMA3 N4BP2 CNTNAP4	5.47e-05	182	162	6	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 SMYD1 SYNJ2 HS3ST2 DNAH6 MAST3	5.47e-05	182	162	6	205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KLHL1 ITPKA SYNJ2 HS3ST2 LYPD8 MAST3	5.47e-05	182	162	6	35b2a5625323bf0917214d3b82fafc4a8f5e75ff
ToppCell	5'-Adult-LymphNode-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RERG MAP1A TP53I11 ANKS1B TPPP3 EML1	5.64e-05	183	162	6	d67454baf0cf791a743b51afd1cb25bfb5765385
ToppCell	18-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	MELK NEK2 MYO3A KIF9 DNAH17 TPPP3	5.64e-05	183	162	6	a75cda2131755931117c387f2e0ae3394efa8e80
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT6A EEPD1 SEMA6A TPPP3 FAR1 KIF13A	5.64e-05	183	162	6	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	5'-Adult-LymphNode-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RERG MAP1A TP53I11 ANKS1B TPPP3 EML1	5.64e-05	183	162	6	e49ac8314b6fe98426b1514ea68d646297b8bc0f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL4 SLITRK2 LOXHD1 GUCY2F CNTNAP4 DNAH11	5.81e-05	184	162	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL4 SLITRK2 LOXHD1 GUCY2F CNTNAP4 DNAH11	5.81e-05	184	162	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL4 SLITRK2 LOXHD1 GUCY2F CNTNAP4 DNAH11	5.81e-05	184	162	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	15-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	MELK NEK2 KIF9 CCDC15 TPPP3 TOP2A	5.99e-05	185	162	6	9a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RERG ERBB4 TP53I11 LAMA3 N4BP2 CNTNAP4	5.99e-05	185	162	6	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 ERBB4 MAP1A AGBL2 DNAH6 DNAH11	5.99e-05	185	162	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CDCA3 LAMA3 MELK NEK2 MYO3A TOP2A	5.99e-05	185	162	6	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ERBB4 TRIM2 NUDT4 SLC2A13 NOS1	5.99e-05	185	162	6	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	CDCA3 RERG MAP1A MELK NEK2 TOP2A	5.99e-05	185	162	6	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RERG ERBB4 TP53I11 LAMA3 EGFL6 CNTNAP4	6.36e-05	187	162	6	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 KIF9 TPPP3 AGBL2 DNAH6 MOG	6.36e-05	187	162	6	e61992de4f98eeea08b43213850769d923f8db48
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RERG ERBB4 EGFL6 MYO3A EEPD1 NOS1	6.55e-05	188	162	6	8268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCell	multiciliated\|World / shred by cell class for bronchial biopsy	DNAH3 MAP1A KIF9 TPPP3 DNAH6 DNAH11	6.55e-05	188	162	6	6833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPKB EEPD1 SEMA6A TPPP3 EML1 CTNND2	6.55e-05	188	162	6	73f6ec915934154f435a376cb274b058ff7c5f35
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ERBB4 WNK1 OPHN1 ITPKB NOS1	6.55e-05	188	162	6	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RERG ERBB4 EGFL6 MYO3A EEPD1 NOS1	6.55e-05	188	162	6	4544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	MAP1A KIF9 TPPP3 AGBL2 DNAH6 DNAH11	6.55e-05	188	162	6	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRIM2 MAP1A ANKS1B ITPKB RAB40B TPPP3	6.55e-05	188	162	6	6c7ce6e28e4433092605880acf127833e7b66ebe
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPKB EEPD1 SEMA6A TPPP3 EML1 CTNND2	6.55e-05	188	162	6	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ERBB4 WNK1 OPHN1 ITPKB NOS1	6.55e-05	188	162	6	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK3 ERBB4 KIF12 LAMA3 TRIM71 CTNND2	6.55e-05	188	162	6	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK3 ERBB4 KIF12 LAMA3 TRIM71 CTNND2	6.55e-05	188	162	6	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	3'_v3-Lung-Myeloid_Dendritic-Cycling_Dendritic\|Lung / Manually curated celltypes from each tissue	CDCA3 MELK NEK2 THBS2 TIMELESS TOP2A	6.55e-05	188	162	6	0e8ac42c439f30a05e015210e1d5c2dcb9d9d471
Drug	5230742; Down 200; 17uM; MCF7; HT_HG-U133A_EA	DNAH3 TRIM2 WEE1 WNK1 SLC1A4 NEK1 SYNJ2 CTNND2 SEC23A BAHCC1	1.52e-06	199	160	10	862_DN
Disease	Polydactyly	EVC2 IFT172 WNT7A LMBR1 SALL4 BBS5 NEK1 LRP4	2.03e-07	117	155	8	C0152427
Disease	Phakomatosis cesioflammea	GNA11 GNAQ	2.74e-05	2	155	2	C3838883
Disease	Congenital hemangioma	GNA11 GNAQ	2.74e-05	2	155	2	C0235753
Disease	Port-wine stain with oculocutaneous melanosis	GNA11 GNAQ	2.74e-05	2	155	2	C1274879
Disease	Cutaneous Melanoma	ERBB4 RET GNA11 GNAQ	6.38e-05	41	155	4	C0151779
Disease	Malignant neoplasm of breast	ERBB4 RPS7 NBN WNK1 CLIP1 PARP1 SYNJ2 GUCY2F ABRAXAS1 N4BP2 SIPA1L1 DIP2C AKT2 TIMELESS MRPL9 TOP2A	1.78e-04	1074	155	16	C0006142
Disease	Malignant melanoma of iris	GNA11 GNAQ	2.71e-04	5	155	2	C0346373
Disease	Malignant melanoma of choroid	GNA11 GNAQ	2.71e-04	5	155	2	C0346388
Disease	pseudohypoaldosteronism (implicated_via_orthology)	WNK1 WNK2	4.06e-04	6	155	2	DOID:4479 (implicated_via_orthology)
Disease	hydrocephalus (is_implicated_in)	MPDZ TRIM71	4.06e-04	6	155	2	DOID:10908 (is_implicated_in)
Disease	erythronate measurement	CACNA1D TKT	5.66e-04	7	155	2	EFO_0021025
Disease	atrioventricular septal defect (implicated_via_orthology)	IFT172 DNAH11	5.66e-04	7	155	2	DOID:0050651 (implicated_via_orthology)
Disease	platelet component distribution width	RERG WEE1 WNK1 C4orf54 KIF9 CLPB SYNJ2 ZPR1 DENND2C GNA12 AGBL2 RAB1A	6.70e-04	755	155	12	EFO_0007984
Disease	Congenital disorder of glycosylation type 1q	SLC35A1 PMM2	7.52e-04	8	155	2	C4317224
Disease	Uveal melanoma	GNA11 GNAQ	7.52e-04	8	155	2	C0220633
Disease	thyroxine measurement	ERBB4 LAMA3 TRIM71 AGBL2	9.75e-04	83	155	4	EFO_0005130
Disease	Seizures	SLC35A1 MPDZ DBT KPTN CLPB NOS1	1.06e-03	218	155	6	C0036572
Disease	Congenital Disorders of Glycosylation	SLC35A1 PMM2	1.20e-03	10	155	2	C0282577
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	AGPAT4 ZPR1 MAST3	1.40e-03	42	155	3	EFO_0008317, EFO_0008596, EFO_0020945
Disease	Adenocarcinoma of large intestine	ERBB4 RIPK1 RET AKT2	1.67e-03	96	155	4	C1319315
Disease	hearing impairment	SALL4 MYO3A LOXHD1 PJVK	1.80e-03	98	155	4	C1384666
Disease	alpha fetoprotein measurement	TRIM26 ARL10 ABRAXAS1 AKT2	1.94e-03	100	155	4	EFO_0010583
Disease	Short Rib-Polydactyly Syndrome	IFT172 NEK1	2.06e-03	13	155	2	C0036996
Disease	Fetal Alcohol Spectrum Disorders	SLITRK2 NOS1	2.06e-03	13	155	2	C2985290
Disease	cortisol measurement, response to corticosteroid, response to synacthen	ANKS1B NOS1	2.06e-03	13	155	2	EFO_0005843, EFO_0009175, GO_0031960
Disease	Saldino-Noonan Syndrome	IFT172 NEK1	2.39e-03	14	155	2	C0036069
Disease	Majewski Syndrome	IFT172 NEK1	2.39e-03	14	155	2	C0024507
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	MYO3A LOXHD1 PJVK	2.46e-03	51	155	3	cv:CN043650
Disease	treatment-resistant hypertension	DOCK3 CACNA1D EML6 TKT	2.66e-03	109	155	4	EFO_1002006
Disease	Ciliopathies	EVC2 BBS5 NEK1 DNAH11	2.75e-03	110	155	4	C4277690
Disease	cortical thickness, neuroimaging measurement	SNX31 GNA12 EML1 MOG	2.75e-03	110	155	4	EFO_0004346, EFO_0004840
Disease	Aganglionosis, Colonic	RET UTP25	2.75e-03	15	155	2	C0085758
Disease	African Burkitt's lymphoma	RET GNA13	2.75e-03	15	155	2	C0343640
Disease	Aganglionosis, Rectosigmoid Colon	RET UTP25	2.75e-03	15	155	2	C1257840
Disease	Burkitt Leukemia	RET GNA13	2.75e-03	15	155	2	C4721444
Disease	syndromic intellectual disability (implicated_via_orthology)	OPHN1 PDZD8	3.13e-03	16	155	2	DOID:0050888 (implicated_via_orthology)
Disease	diacylglycerol 44:7 measurement	IFT172 ZPR1	3.13e-03	16	155	2	EFO_0020069
Disease	Congenital Intestinal Aganglionosis	RET UTP25	3.54e-03	17	155	2	C3661523
Disease	Fetal Alcohol Syndrome	SLITRK2 NOS1	3.54e-03	17	155	2	C0015923
Disease	reticulocyte count	TRIM2 EML6 ASH1L LAMA3 CLIP1 NUDT4 GIMAP8 GNA13 ZPR1 EEPD1 DNAH17 MAST1 RAB1A	3.57e-03	1045	155	13	EFO_0007986
Disease	frontal pole volume measurement	DIP2C NOS1	3.97e-03	18	155	2	EFO_0010304
Disease	peritonsillar abscess	KLHL1 GNA12	3.97e-03	18	155	2	EFO_0007429
Disease	unipolar depression	ERBB4 TRIM26 ASH1L STEAP2 ANO8 ITPKB NBAS TKT EML1 CTNND2 HS3ST2 DNAH6 NOS1 MOG	4.64e-03	1206	155	14	EFO_0003761
Disease	colorectal cancer	DOCK3 ERBB4 HAO1 WNK1 SYNJ2 SNX31 GNA12 NOS1 SYMPK	4.78e-03	604	155	9	MONDO_0005575
Disease	Deaf Mutism	CACNA1D PJVK	4.90e-03	20	155	2	C4082305
Disease	Deafness, Acquired	CACNA1D PJVK	4.90e-03	20	155	2	C0751068
Disease	Hearing Loss, Extreme	CACNA1D PJVK	4.90e-03	20	155	2	C0086395
Disease	Complete Hearing Loss	CACNA1D PJVK	4.90e-03	20	155	2	C0581883
Disease	Bilateral Deafness	CACNA1D PJVK	4.90e-03	20	155	2	C3665473
Disease	Prelingual Deafness	CACNA1D PJVK	4.90e-03	20	155	2	C0011052

Protein segments in the cluster

Peptide	Gene	Start	Entry
KDRKRILITGGAGFV	UXS1	86	Q8NBZ7
KKSRGAGELAGTLTF	ZNF385A	301	Q96PM9
GFLLGEVKGEAKNSI	ABRAXAS1	31	Q6UWZ7
GTFGKVILVREKATG	AKT2	161	P31751
TELKRVKVLGSGAFG	ERBB4	716	Q15303
LLRKGEKFGRGVIAG	EOLA1	71	Q8TE69
LLRKGEKFGRGVIAG	EOLA2	71	Q96DE9
DRFLVGKELGREKAG	BAHCC1	216	Q9P281
GLAIEKLKDGFTLQG	BBS5	321	Q8N3I7
KKSGFGRENGRVTIE	ALDH9A1	461	P49189
AGLVSKDLIRKAGVG	ASH1L	246	Q9NR48
KDLIRKAGVGSVAGI	ASH1L	251	Q9NR48
KSIIFEAERGKGKTG	EGFL6	516	Q8IUX8
RLRGFEGKLTAQGKL	ARHGEF25	341	Q86VW2
GSGLKRKFDDVDVGS	CSRNP2	6	Q9H175
SGGILLFLSDGKLKS	CNTNAP4	416	Q9C0A0
KLERLEFGGTKGAIL	DNAH11	486	Q96DT5
GTGKTETTKDLGRAL	DNAH11	1896	Q96DT5
RVGTKGLDFSDRIGK	DCTN2	61	Q13561
GLDFSDRIGKTKRTG	DCTN2	66	Q13561
LRDAGGIEKLVGISK	CTNND2	981	Q9UQB3
IGGFKKVEDLALVSG	EEPD1	71	Q7L9B9
GLRLKKVSFAERGAG	ANO8	611	Q9HCE9
LKEGAILGTGRLLKT	CDCA3	231	Q99618
LFKLLLIGDSGVGKS	RAB1A	11	P62820
KFLLVGDSDVGKGEI	RAB40B	16	Q12829
KFLLVGDSDVGKGEI	RAB40C	16	Q96S21
RLKTRKILGVGGEDD	TP53I11	21	O14683
SFKITRGIEAVGGKL	UQCRC2	96	P22695
SLFKVILLGDGGVGK	RAB9A	6	P51151
RVKVLVLGDSGVGKS	RABL3	6	Q5HYI8
GKLVSRLQDGGTKIT	OPHN1	671	O60890
LEKGGKVFSATLGLV	PARP1	546	P09874
KLLLLGTGESGKSTF	GNAQ	41	P50148
SKKIGERAILLGGLI	MFSD8	331	Q8NHS3
FVIGGKTRGSRDIKS	KBTBD3	406	Q8NAB2
RKGAKVFGSLERGLD	MELK	521	Q14680
DGAGKSTFLRVLSGK	ARL10	86	Q8N8L6
VALVEKLLSGRKGGI	ANKS1B	16	Q7Z6G8
IKLSEVVGSGKDGRI	DBT	186	P11182
VVGSGKDGRILKEDI	DBT	191	P11182
GVKKGGTRAVLEFIR	HS3ST2	121	Q9Y278
DVTGALKRALGRFKG	OR2T1	346	O43869
KGSFVGNIVKDLGLE	PCDHGA6	41	Q9Y5G7
GSIIGKKGESVKRIR	PCBP1	26	Q15365
VRKTGEFAIVSGKLE	PNLIPRP3	381	Q17RR3
TGATGFLGKVLLEKL	FAR1	16	Q8WVX9
KVILRFTDFKLDGTG	LRP12	296	Q9Y561
LTKATGDGLKRALQG	TRIM71	486	Q2Q1W2
SEKRGEIIGKGLSGE	MAP1A	921	P78559
KGRLVFALGTDGKKL	LAMA3	3041	Q16787
IDLIDGKGRGVIATK	KMT5A	261	Q9NQR1
GEGSFGKAILVKSTE	NEK1	11	Q96PY6
GGDLASVITKGTKER	NEK2	91	P51955
AGVKGKLGRLLGIFE	NUDT4B	71	A0A024RBG1
VGGREILKGKLFDST	NUDCD2	56	Q8WVJ2
GLGERKAERAGKTGL	GPR179	1186	Q6PRD1
KLTKLLADSLGGRGV	KIF12	316	Q96FN5
LESEGFAGLKKGIRA	LMBR1	131	Q8WVP7
SIGRLFGKKEKGRLI	PPFIA4	756	O75335
GIKGTVKRSTDGDFI	METTL14	291	Q9HCE5
TIFGANGDTGKRELK	LOXHD1	1971	Q8IVV2
KFTGLKTALILGGDR	DDX54	191	Q8TDD1
FTLRDEGKTIAIGKV	GSPT2	606	Q8IYD1
GTRSGSLKKVRVDGF	PLXNA3	431	P51805
GGRGELLAATLKGKV	KPTN	36	Q9Y664
TVLGIATGEGRKKAL	OR51J1	226	Q9H342
AGVKGKLGRLLGIFE	NUDT4	71	Q9NZJ9
STGIKLVRKEGGLDD	PDZD8	996	Q8NEN9
LEKLRASGAGKAIGV	PFKL	6	P17858
DGGVRKGTDVLKALA	HAO1	291	Q9UJM8
DGKLRGDLISRGLEK	EVC2	1196	Q86UK5
RLGKSGSEGQVLKEA	KIF9	251	Q9HAQ2
GRIAGKGGKTKFTIE	PNO1	181	Q9NRX1
KRLVKILLLGAGESG	GNA13	46	Q14344
GRAGKSGVAITFLTK	DDX23	756	Q9BUQ8
GLKGTDLEALLAIGK	NBAS	606	A2RRP1
GRTELLKDAIGEGKV	MOG	96	Q16653
GKREGLGGLTLREKT	MAST1	751	Q9Y2H9
REATKKGARGVEGFV	IFT172	1266	Q9UG01
TTLGFRIEGIKKADG	ITPKA	326	P23677
ISVRLFKRKVGGLGF	NOS1	16	P29475
SRIVKGGAAEKSGLL	PALS1	281	Q8N3R9
EVRIKATDGGGLSGK	PCDHB16	316	Q9NRJ7
KLIKRAVEGLAESGG	KAT6A	101	Q92794
KARAGEIKGFTGIDS	PAPSS1	176	O43252
GARGSRKVADGLVKV	DCTN3	26	O75935
EGERVSLGKGLKARG	DNAH6	1261	Q9C0G6
SVLAEGKGGFIRAKL	FBH1	541	Q8NFZ0
LTLEKGDFERGGKSV	DOCK3	426	Q8IZD9
EFLKLEKIELGGVRG	DNAH17	436	Q9UFH2
TGKTETTKDLGRALG	DNAH17	1851	Q9UFH2
RAEKLISGLGGEKDR	DNAH3	2966	Q8TD57
KLLLLGTGESGKSTF	GNA11	41	P29992
VELRGRTELKGKGTE	GUCY2F	1041	P51841
SELTVLLVGKRGAGK	GIMAP8	246	Q8ND71
RKLGEGSFAKVREGL	HUNK	66	P57058
KGGLFKTDRVLGTAQ	CC2D1A	741	Q6P1N0
SKGGLVGFSRALAKE	CBR4	151	Q8N4T8
KGLGSQTESLKARGL	DIP2C	1241	Q9Y2E4
RLVKILLLGAGESGK	GNA12	56	Q03113
LLLGAGESGKSTFLK	GNA12	61	Q03113
SSRVGGKRGIVKELA	AGBL2	241	Q5U5Z8
GFIQDRELRKSGVKG	DENND2C	876	Q68D51
VGKDLLKGSLLFTAG	BLVRA	141	P53004
FRGDAGLGKLIKIFE	IFI16	56	Q16666
LSGENKTLGGVIFRK	LYPD8	181	Q6UX82
LGHIKLTDFGLSKIG	MAST3	501	O60307
FDEGRLTDGKGKTID	CLPB	471	Q9H078
DGTLVSGGGKDRKLI	EML1	471	O00423
AKRGIFGKTGDLQTI	EML6	186	Q6ZMW3
KLSKRLGEVEERGTG	C4orf54	1311	D6RIA3
GKLAGRLKEASEGST	S1PR3	26	Q99500
LLGTDGKRVSEIFPK	SALL4	941	Q9UJQ4
VLGVLSGEFSKEREK	CACNA1D	401	Q01668
ELKIGDRVLVGGTKA	CLIP1	211	P30622
VGVKKGGTRALLEFL	HS3ST6	96	Q96QI5
VRGSKGAKDGALTLL	PAK4	71	O96013
KTGAAGERLKEGSNI	KIF13A	261	Q9H1H9
EKVGRRKLTFGSLAG	SLC2A13	386	Q96QE2
LRKEFAGKGLTFSIG	PMM2	161	O15305
GILAKETGSLGRFKA	SLC35A1	61	P78382
RTIIGGEGEKKRDFD	UTP25	456	Q68CQ4
TAAKEIEVGGGRKAI	RPS7	46	P62081
VFTGSRALEGKAKVG	SYNJ2	441	O15056
KKLSSAVVFGGGEAR	NBN	236	O60934
KLERIGKGSFGEVFK	STK26	26	Q9P289
TATLGFRIEGIKKED	ITPKB	806	P27987
VFTAEGKGRGLKATK	SMYD1	11	Q8NB12
GAGLFVFVLKRRKGV	SLITRK2	636	Q9H156
IGGEGERKISLSKSN	SIPA1L1	421	O43166
KDARKVTVGVIGSGD	STEAP2	26	Q8NFT2
VKGGSSKLTGRVLAL	WDR13	296	Q9H1Z4
LREVDGTAKKNGGTL	RIPK1	176	Q13546
GFGGTLEIKTSREIK	SEC23A	401	Q15436
GLFLIRFGKEGKLSV	SNX31	161	Q8N9S9
EVKLAIFGRAGVGKS	RERG	6	Q96A58
LVTDEKGKEDLFGRG	CCDC15	266	Q0P6D6
RLVELGQSSGKKAGD	ATG4D	231	Q86TL0
GVRGDLVSVKKSLGR	MRPL9	106	Q9BYD2
GLKSIGERDLIFHKG	TIMELESS	286	Q9UNS1
VLGGKFTTLEGLLKD	ZPR1	346	O75312
ELEKIGSGEFGSVFK	WEE1	301	P30291
IELEKGSKGLGFSIL	MPDZ	701	O75970
TKSFVKQVGDGGRLV	PJVK	6	Q0ZLH3
TAIIAKTFKGRGITG	TKT	236	P29401
KTFKGRGITGVEDKE	TKT	241	P29401
KRGESFGISRIGSKI	SNX14	496	Q9Y5W7
LVLGVALKKLGSEGE	SLC1A4	231	P43007
GSEKGIILKFLARIG	SEMA6A	441	Q9H2E6
SSLGKRGVNADKVGI	RTCA	261	O00442
ELTEGREKFKSRGVG	TRIM26	216	Q12899
GAGGRKKIFRLSDVL	SYMPK	536	Q92797
RKNLVLGKTLGEGEF	RET	721	P07949
VGVTKAKTGGAVDRL	TPPP3	111	Q9BW30
EIGKTLAEKSRGLFS	ZRANB2	51	O95218
KTLAVSGLGVVGRDK	TOP2A	466	P11388
ALGERTVFGKELKVG	WNT7A	86	O00755
RFGLLGGSKVLAKKE	AGPAT4	111	Q9NRZ5
KQDGKSRGTLLALEG	THBS2	91	P35442
LKFDIEIGRGSFKTV	WNK1	221	Q9H4A3
GSVKIGDLGLATLKR	WNK2	336	Q9Y3S1
DLIFRVGTKGRNKGE	TRIM2	471	Q9C040
DRSGDVATGLKGKLQ	TTC27	681	Q6P3X3
VKKGSTAVGVRGRDI	PSMA7	26	O14818
DKLFVIGGRDGLKTL	KLHL1	506	Q9NR64
TIEFAGLDGSKRKVL	LRP4	926	O75096
GSVTDLVKGFLKRGE	MYO3A	106	Q8NEV4
SDSIKVLTGRLDGFK	N4BP2	1036	Q86UW6