Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2C SETD1B

3.23e-058222GO:0140945
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2C SETD1B

5.19e-0510222GO:0140999
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2C SETD1B

2.18e-0420222GO:0042800
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2C SETD1B

1.07e-0344222GO:0140938
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2C SETD1B

2.53e-0368222GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2C SETD1B

2.60e-0369222GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2C SETD1B

2.75e-0371222GO:0042054
DomainPost-SET_dom

KMT2C SETD1B

1.43e-0416212IPR003616
DomainPostSET

KMT2C SETD1B

1.43e-0416212SM00508
DomainPOST_SET

KMT2C SETD1B

1.43e-0416212PS50868
DomainZF_RING_2

ZNRF3 CBLB KMT2C RNF215

3.07e-04298214PS50089
DomainRING

ZNRF3 CBLB KMT2C RNF215

3.35e-04305214SM00184
DomainZnf_RING

ZNRF3 CBLB KMT2C RNF215

4.31e-04326214IPR001841
DomainZnf_C3HC4_RING-type

ZNRF3 CBLB RNF215

9.03e-04172213IPR018957
DomainSET

KMT2C SETD1B

9.62e-0441212PF00856
DomainSET

KMT2C SETD1B

1.21e-0346212SM00317
Domain-

ZNRF3 CBLB KMT2C RNF215

1.43e-034492143.30.40.10
DomainSET_dom

KMT2C SETD1B

1.43e-0350212IPR001214
DomainSET

KMT2C SETD1B

1.43e-0350212PS50280
Domainzf-RING_2

ZNRF3 RNF215

1.54e-0352212PF13639
DomainZnf_RING/FYVE/PHD

ZNRF3 CBLB KMT2C RNF215

1.55e-03459214IPR013083
Domainzf-C3HC4

ZNRF3 CBLB RNF215

1.91e-03223213PF00097
DomainC1

TNS2 KMT2C

2.40e-0365212SM00109
DomainPE/DAG-bd

TNS2 KMT2C

2.47e-0366212IPR002219
DomainZF_RING_1

ZNRF3 CBLB RNF215

4.04e-03291213PS00518
Domain-

PTPRN TNS2

4.74e-03922123.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPRN TNS2

5.47e-0399212IPR029021
DomainSH2

CBLB TNS2

6.71e-03110212SM00252
DomainSH2

CBLB TNS2

6.83e-03111212PS50001
DomainSH2

CBLB TNS2

6.95e-03112212IPR000980
Domain-

CBLB TNS2

6.95e-031122123.30.505.10
DomainGrowth_fac_rcpt_

EPHB3 IGFBP2

1.31e-02156212IPR009030
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

KMT2C SETD1B

1.07e-05822223130995
Pubmed

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.

KMT2C SETD1B

1.07e-05822222266653
Pubmed

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

KMT2C SETD1B

1.37e-05922222665483
Pubmed

Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.

GABBR2 PIANP

1.71e-051022230902970
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

KMT2C SETD1B

2.51e-051222227563068
Pubmed

Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro.

KMT2C SETD1B

3.99e-051522235907431
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

KMT2C SETD1B

4.56e-051622223870121
Pubmed

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.

KMT2C SETD1B

4.56e-051622224368734
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ZNRF3 KMT2C SNX15 WNK2 BRD4 SETD1B

4.89e-05110522635748872
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

KMT2C SETD1B

7.21e-052022229785026
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

KMT2C SETD1B

8.76e-052222226886794
Pubmed

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.

CBLB WNK2 BRD4 SETD1B

1.28e-0441922433001583
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

ZNRF3 CBLB FREM2 SETD1B

1.43e-0443122433660365
Pubmed

Identification and characterization of a novel human PP1 phosphatase complex.

KMT2C SETD1B

1.76e-043122220516061
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

KMT2C XIRP1 WNK2

4.16e-0423322337704626
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

KMT2C SETD1B

4.59e-045022237974198
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ZNRF3 PTPRN TNS2 WNK2

5.27e-0460822416713569
Pubmed

New nomenclature for chromatin-modifying enzymes.

KMT2C SETD1B

5.97e-045722218022353
CytobandEnsembl 112 genes in cytogenetic band chr2q35

PTPRN IGFBP2

1.74e-03129222chr2q35
CytobandEnsembl 112 genes in cytogenetic band chr9q22

GABBR2 WNK2

4.12e-03200222chr9q22
CytobandEnsembl 112 genes in cytogenetic band chr3q13

CBLB NECTIN3

5.00e-03221222chr3q13
CytobandEnsembl 112 genes in cytogenetic band chr22q12

ZNRF3 RNF215

5.63e-03235222chr22q12
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C SETD1B

2.64e-0434132487
GeneFamilyRing finger proteins

ZNRF3 CBLB RNF215

8.89e-0427513358
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 WNK2 NECTIN3 IGFBP2

3.79e-08197225c0250509836f1be04f5e54386191d7bb1e1da652
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 WNK2 NECTIN3 IGFBP2

3.89e-08198225e8bfae3888b2406b5629b576cb02913b3297337e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 WNK2 IGFBP2

1.30e-061682243e3f611e9bbec8224264666be14a4e7db343070e
ToppCell5'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 WNK2 IGFBP2

1.91e-06185224655a9357a7711cefb48395e0b2a5a0ab90bcf3f5
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 WNK2 IGFBP2

2.40e-0619622497324c9e93f833e1f218e81fb53066d44c6892df
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNRF3 WNK2 NECTIN3 IGFBP2

2.50e-06198224a4543d636501a1b5b46c14a661ce9d169947c82c
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NECTIN3 IGFBP2 WIPF3

3.65e-05132223ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABBR2 ZNRF3 IGFBP2

4.83e-051452238da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 IGFBP2

6.47e-051602236005948e400e781cdb876ba350b3ec8991e3945f
ToppCell5'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 WNK2 IGFBP2

6.71e-05162223472194eccc29c905010e2d8faa67c1a07d5e7118
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA2012 FREM2 DNAH1

6.96e-05164223e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PTPRN IGFBP2 APCDD1L

6.96e-0516422385487a303194f5244956ec1ca2d1758d38117f41
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PTPRN KMT2C IGFBP2

7.48e-051682238c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellPericytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

XIRP1 APCDD1L WIPF3

7.88e-05171223bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FREM2 IGFBP2 WIPF3

8.15e-0517322345808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FREM2 IGFBP2 WIPF3

8.15e-051732237fa9dbcb258c3ab974490063951620e2def03db1
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNRF3 IGFBP2 WIPF3

8.44e-05175223a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 IGFBP2

8.44e-051752230431897d7fcc9cefb516cd36987cf18b7f19a26a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

8.72e-051772234d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

8.87e-05178223edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.02e-051792237394e77e665bf16d3733df91bb12907be460ab44
ToppCellCiliated_cells-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

KIAA2012 WNK2 RNF215

9.02e-051792231c41314b6fcfcac8d62034e7037570120d58f20f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.32e-051812235bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.32e-051812238e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

CBLB IGFBP2 WIPF3

9.63e-05183223fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.63e-051832233c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.63e-051832237c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.63e-05183223612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.63e-05183223848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.63e-05183223eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.63e-051832239c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.79e-051842237294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.94e-051852239197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNRF3 FREM2 NECTIN3

9.94e-051852230d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.94e-05185223b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB3 FREM2 DNAH1

9.94e-0518522305bc89a566b0db90ae06506e067190a4739a0974
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB IGFBP2 WIPF3

9.94e-05185223ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN XIRP1 WNK2

1.04e-041882234db566f3f708e66730aa9e16f4d73d91dc534177
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN XIRP1 WNK2

1.04e-041882236704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN XIRP1 WNK2

1.09e-041912239d7d680da3979e256191b534ebd14c5383e0cf93
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA2012 XIRP1 WNK2

1.09e-041912238e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NECTIN3 IGFBP2 WIPF3

1.09e-04191223ce76b156b153a2c7c9f2fb8e563b69c81073fbe5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NECTIN3 IGFBP2 WIPF3

1.09e-04191223c006f5a6e3a32b79ac99a78304bdd5116fc0d5e0
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN XIRP1 WNK2

1.09e-04191223543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIAA2012 C16orf96 DNAH1

1.09e-0419122396483adb97c81208aa513782550acd8a08b63866
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CBLB IGFBP2 WIPF3

1.09e-04191223c4a2a8a7b864df282546e6ac53fcb2269cbb3345
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FREM2 IGFBP2 WIPF3

1.09e-041912234c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZNRF3 FREM2 NECTIN3

1.11e-04192223fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NECTIN3 IGFBP2 WIPF3

1.11e-04192223790282d4232311df3dac4ad97c80fc53443beccc
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NECTIN3 IGFBP2 WIPF3

1.11e-04192223b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZNRF3 FREM2 NECTIN3

1.11e-0419222387b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABBR2 PTPRN WIPF3

1.13e-04193223be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GABBR2 PTPRN PIANP

1.13e-04193223b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABBR2 EPHB3 IGFBP2

1.13e-04193223efa91167dc7a59bf32addf90ffb7bf070b2a0151
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABBR2 PTPRN WIPF3

1.13e-041932230c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABBR2 PTPRN WIPF3

1.13e-041932238689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 IGFBP2

1.14e-0419422346e522ca59db545d1eb0c27cd4361f19d4f8f762
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

GABBR2 PTPRN PIANP

1.14e-041942238aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

GABBR2 NECTIN3 IGFBP2

1.14e-041942234903a0d6e36599bcb83b179462e5b949df9eb685
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 WNK2

1.16e-04195223b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

NECTIN3 IGFBP2 WIPF3

1.18e-04196223484bbc6b1f58bc260964babb949d14f5df101393
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NECTIN3 IGFBP2 WIPF3

1.18e-041962239790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NECTIN3 IGFBP2 WIPF3

1.18e-04196223b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABBR2 EPHB3 IGFBP2

1.20e-04197223196eaecef7003ed83f323c1f157c6a3594650097
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 NECTIN3 IGFBP2

1.20e-041972239ae6d987e65972e1fb21aa407788d5e3ff41ad64
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZNRF3 FREM2 IGFBP2

1.22e-04198223eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZNRF3 FREM2 IGFBP2

1.22e-0419822384697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

WNK2 DNAH1 WIPF3

1.22e-04198223e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

WNK2 DNAH1 WIPF3

1.22e-04198223ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WNK2 RNF215 IGFBP2

1.22e-0419822324bc53bd8ef8f4f2f4fc377aeee75126ad5d311f
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZNRF3 FREM2 IGFBP2

1.23e-04199223debdd7dba774d9ccff7effc3f4c132393d203dfa
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GABBR2 PTPRN PIANP

1.23e-04199223f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 ZNRF3 WNK2

1.23e-04199223f544229f471b4717166dd4b588399afe45cc31b5
ToppCellwk_08-11-Epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZNRF3 FREM2 IGFBP2

1.25e-04200223445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPHB3 WNK2 WIPF3

1.25e-0420022385c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

C16orf96 XIRP1

8.52e-04882225fdfc72988dcbb7d2025866b2b00eab8f11f332f
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

C16orf96 XIRP1

8.52e-0488222b9874366925fa1c08a74b14c3c6e127b9dffa23e
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)|Cerebellum / BrainAtlas - Mouse McCarroll V32

EPHB3 KIAA2012

1.40e-031132227e24c0f6a80e10a2a41325d48a87628bd330a1e2
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

EPHB3 KIAA2012

1.40e-03113222c0b8d7a2e3722029e850051bdff77f31f34a8cca
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

EPHB3 KIAA2012

1.40e-03113222fed408864201218295bac0cc6647953fda8d688e
ToppCellMyeloid-Myeloid-C_(Cd16+_Monocyte)|Myeloid / shred on cell class and cell subclass (v4)

PTPRN WIPF3

1.50e-03117222d1936e76a935216783a73ab414e4147fa48e68eb
ToppCellControl-Epithelial_alveolar-AT_2-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH1 WIPF3

1.50e-03117222c6fc72608d56a389bcd87b5dc98a11e39b79bcb2
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB3 WNK2

1.65e-03123222a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellileum-Epithelial_Stem_Cells|ileum / shred on tissue and cell subclass

EPHB3 FREM2

1.73e-03126222a8ed48cbd1e207fd1aaad454fda9f329eb22aa83
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNS2 DNAH1

1.81e-031292222f30b4897343586c9b49a1d2bec3007ec737085c
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|bone_marrow / Manually curated celltypes from each tissue

GABBR2 PIANP

1.81e-03129222426dfed68ce7ccc38d02e671e722e201f9eb1ce0
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1|Hippocampus / BrainAtlas - Mouse McCarroll V32

EPHB3 WIPF3

1.84e-03130222c70fb77324916d220d842a575558a8245c276599
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-immature_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN PIANP

1.90e-031322229936078c328b1e1d59f9dfdd69d36926a0cdaf0d
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|343B / Donor, Lineage, Cell class and subclass (all cells)

SETD1B DNAH1

1.93e-031332228ff1cf0ea1fc33fe8384c0e65c1ee1853b25a2ae
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

C16orf96 APCDD1L

1.98e-031352227b456fa9a5f5ce58976a8f1fad18c0f96a096930
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PTPRN APCDD1L

2.01e-03136222feb957df4bff3266cb9a7382b16fc927ae03b9b4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NECTIN3 RNF215

2.04e-031372220c82f815c014d01213d23b466043d6e57186dceb
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

GABBR2 KIAA2012

2.10e-0313922264c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellprimary_visual_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRN WIPF3

2.16e-03141222605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NECTIN3 WIPF3

2.19e-03142222d08e1880425d285c4433014fe0242ac7ff7734af
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 IGFBP2

2.19e-03142222a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 IGFBP2

2.19e-03142222d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EPHB3 FREM2

2.22e-0314322227e06327f96cb72bd111ea6ece6307e5ebb3a146
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EPHB3 FREM2

2.22e-031432224edef95ae2a1ef4fc4b0d4fadf75bfc54b583932
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPHB3 WNK2

2.22e-0314322292ddc3e3f6ba78dd9daeb272c12503ec2650a874
Diseaseparahippocampal gyrus volume measurement

EPHB3 FREM2

8.06e-0518222EFO_0010318
Diseasestomach carcinoma (is_marker_for)

CBLB KMT2C

1.45e-0424222DOID:5517 (is_marker_for)
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

CBLB PTPRN

3.87e-0439222DOID:9744 (implicated_via_orthology)
Diseasemean corpuscular hemoglobin concentration

ZNRF3 KIAA2012 C16orf96 BRD4 SETD1B

1.13e-031105225EFO_0004528
Diseasetype 1 diabetes mellitus (is_implicated_in)

CBLB PTPRN

1.82e-0385222DOID:9744 (is_implicated_in)
DiseaseAdenoid Cystic Carcinoma

KMT2C IGFBP2

2.51e-03100222C0010606
Diseasemosquito bite reaction itch intensity measurement

CBLB NECTIN3

4.14e-03129222EFO_0008377
Diseaselung non-small cell carcinoma (is_implicated_in)

CBLB KMT2C

4.78e-03139222DOID:3908 (is_implicated_in)
Diseasecognitive decline measurement

GABBR2 CBLB IGFBP2

5.42e-03486223EFO_0007710
DiseaseLeukemia, Myelocytic, Acute

CBLB KMT2C

7.31e-03173222C0023467
Diseasecolorectal health

CBLB XIRP1

9.75e-03201222EFO_0008460

Protein segments in the cluster

PeptideGeneStartEntry
PILHLPQPELPPHLP

BRD4

826

O60885
HPPVLPPPLALPLHL

APCDD1L

266

Q8NCL9
LPPLLEHLLLPPQPP

PTPRN

181

Q16849
PAHLPLNPPRIQPPI

KMT2C

3341

Q8NEZ4
QPGPPPPPRLLLLLL

FREM2

21

Q5SZK8
PLQIPHLSLPPVPPR

CBLB

496

Q13191
PLPPPPLLPLLLLLL

IGFBP2

11

P18065
PPHDVAPPLDLLPPI

KIAA2012

531

Q0VF49
SPPPGLLPLLPPLLL

EPHB3

11

P54753
NPPALDPKLPHLPLP

DNAH1

51

Q9P2D7
RPPSLPPLLLLPPLI

C16orf96

1091

A6NNT2
PPPPPARLLLLLLLP

GABBR2

16

O75899
PLWPLLLLPLPPPAQ

PIANP

16

Q8IYJ0
PPPPPSPLLLLLPLL

RNF215

16

Q9Y6U7
GLPLPLPLPLPLPLA

SETD1B

1471

Q9UPS6
QLAPLHLPPIPPPLP

WIPF3

251

A6NGB9
RDLHILPPPLIPTPP

SNX15

136

Q9NRS6
LPPPPPLPLLLGLLL

ZNRF3

31

Q9ULT6
PALPVRPEPLQPHLP

WNK2

996

Q9Y3S1
DLPLPPPPALEDLPL

XIRP1

21

Q702N8
LHPVRPGHPLPLLLP

TNS2

726

Q63HR2
LQPPTPPPLLLLLFP

NECTIN3

31

Q9NQS3