Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotease binding

HSPG2 CD177 LRP1 APC PRKN TNFAIP3

5.67e-05181746GO:0002020
GeneOntologyMolecularFunctionstructural molecule activity

HSPG2 ANK2 KRTAP3-3 KRTAP3-2 LAMA3 LAMB1 ODF2 SSPOP MUC5AC KRT38 KRT37

4.19e-048917411GO:0005198
GeneOntologyMolecularFunctionamyloid-beta binding

HSPG2 LRP1 CHRFAM7A CHRNA7

5.61e-04102744GO:0001540
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 LAMA3 LAMB1 SSPOP MUC5AC

6.68e-04188745GO:0005201
GeneOntologyMolecularFunctionproteoglycan binding

NF1 SLIT1 LRP1

8.95e-0451743GO:0043394
GeneOntologyMolecularFunctionacetylcholine binding

CHRFAM7A CHRNA7

1.03e-0313742GO:0042166
GeneOntologyMolecularFunctionchloride channel regulator activity

CHRFAM7A CHRNA7

1.38e-0315742GO:0017081
GeneOntologyMolecularFunctionadenylate cyclase binding

CHRFAM7A CHRNA7

1.57e-0316742GO:0008179
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 LRP1

1.57e-0316742GO:0005041
GeneOntologyMolecularFunctionacetylcholine-gated monoatomic cation-selective channel activity

CHRFAM7A CHRNA7

1.78e-0317742GO:0022848
GeneOntologyMolecularFunctiontoxic substance binding

CHRFAM7A CHRNA7

1.99e-0318742GO:0015643
GeneOntologyMolecularFunctionprotein kinase activator activity

MT3 MOB3C NRG3 MOB3A

2.29e-03149744GO:0030295
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 LRP1

2.72e-0321742GO:0030228
GeneOntologyMolecularFunctionprotein kinase regulator activity

MT3 APC MOB3C NRG3 MOB3A

2.75e-03259745GO:0019887
GeneOntologyMolecularFunctionkinase activator activity

MT3 MOB3C NRG3 MOB3A

2.89e-03159744GO:0019209
GeneOntologyMolecularFunctionenzyme activator activity

RALGAPA1 MT3 NF1 ARHGAP31 MOB3C RGS9 NRG3 MOB3A

2.91e-03656748GO:0008047
GeneOntologyMolecularFunctionkinase binding

SOX9 ANK2 APC PRKN TRIM34 DUSP10 TNFAIP3 NRG3 CHRFAM7A CHRNA7

2.96e-039697410GO:0019900
GeneOntologyMolecularFunctionacetylcholine receptor activity

CHRFAM7A CHRNA7

3.26e-0323742GO:0015464
GeneOntologyMolecularFunctionK63-linked polyubiquitin modification-dependent protein binding

RNF168 TNFAIP3

4.16e-0326742GO:0070530
GeneOntologyMolecularFunctionscavenger receptor activity

STAB2 LRP1

4.48e-0327742GO:0005044
GeneOntologyBiologicalProcessamyloid fibril formation

HSPG2 CDSN PRKN CHRFAM7A CHRNA7

5.66e-0745745GO:1990000
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

MPL SOX9 HSPG2 MT3 NF1 HECW2 SLIT1 LRP1 APC PRKN GRN TNFAIP3 FUT1 CHRNA7 NOTCH4

6.15e-0610907415GO:0022603
GeneOntologyBiologicalProcesspositive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

CHRFAM7A CHRNA7

1.27e-052742GO:0001988
GeneOntologyBiologicalProcessregulation of cell adhesion

SOX9 MYF5 HSPG2 CDSN NF1 LRP1 APC LAMA3 LAMB1 DUSP10 TNFAIP3 FUT1 NOTCH4

2.30e-059277413GO:0030155
GeneOntologyBiologicalProcessbaroreceptor response to decreased systemic arterial blood pressure

CHRFAM7A CHRNA7

3.80e-053742GO:0001982
GeneOntologyBiologicalProcessregulation of amyloid fibril formation

HSPG2 CHRFAM7A CHRNA7

4.12e-0519743GO:1905906
GeneOntologyBiologicalProcessgeneration of ovulation cycle rhythm

CHRFAM7A CHRNA7

7.58e-054742GO:0060112
GeneOntologyBiologicalProcessastrocyte activation involved in immune response

LRP1 GRN

7.58e-054742GO:0002265
GeneOntologyBiologicalProcessnegative regulation of MAPK cascade

NF1 APC PRKN DUSP10 CHRFAM7A CHRNA7

8.49e-05201746GO:0043409
GeneOntologyBiologicalProcessregulation of epithelial cell proliferation

SOX9 HSPG2 NF1 APC LAMB1 GRN DUSP10 TNFAIP3 FUT1

9.07e-05514749GO:0050678
GeneOntologyBiologicalProcessERK1 and ERK2 cascade

SOX9 MT3 NF1 LRP1 DUSP15 DUSP10 CHRFAM7A CHRNA7

1.25e-04418748GO:0070371
GeneOntologyBiologicalProcesssensory processing

CHRFAM7A CHRNA7

1.26e-045742GO:0050893
GeneOntologyBiologicalProcessneuron projection morphogenesis

HSPG2 MT3 HECW2 SLIT1 LRP1 APC LAMA3 LAMB1 PRKN CHRFAM7A CHRNA7

1.28e-048027411GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

HSPG2 MT3 HECW2 SLIT1 LRP1 APC LAMA3 LAMB1 PRKN CHRFAM7A CHRNA7

1.54e-048197411GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

HSPG2 MT3 HECW2 SLIT1 LRP1 APC LAMA3 LAMB1 PRKN CHRFAM7A CHRNA7

1.66e-048267411GO:0048858
GeneOntologyBiologicalProcessendocytosis

HSPG2 STAB2 ANK2 ZFYVE16 CD177 LRP1 PRKN GRN HEATR5A CHRFAM7A CHRNA7

1.68e-048277411GO:0006897
GeneOntologyBiologicalProcessnegative regulation of respiratory burst involved in inflammatory response

GRN DUSP10

1.89e-046742GO:0060266
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback

CHRFAM7A CHRNA7

1.89e-046742GO:0001978
GeneOntologyBiologicalProcessnegative regulation of inflammatory response

GRN DUSP10 TNFAIP3 CHRFAM7A MACIR CHRNA7

2.18e-04239746GO:0050728
GeneOntologyBiologicalProcessregulation of epithelial cell migration

SOX9 NF1 APC GRN DUSP10 FUT1 MACIR

2.33e-04344747GO:0010632
GeneOntologyBiologicalProcesssynaptic transmission, dopaminergic

PRKN CHRFAM7A CHRNA7

2.67e-0435743GO:0001963
GeneOntologyBiologicalProcesscell morphogenesis

MPL HSPG2 MT3 HECW2 SLIT1 LRP1 APC LAMA3 LAMB1 PRKN CHRFAM7A CHRNA7 NOTCH4

2.96e-0411947413GO:0000902
GeneOntologyBiologicalProcessepithelial cell proliferation

SOX9 HSPG2 NF1 APC LAMB1 GRN DUSP10 TNFAIP3 FUT1

2.99e-04603749GO:0050673
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

HSPG2 MT3 HECW2 SLIT1 LRP1 APC LAMA3 LAMB1 CHRFAM7A CHRNA7

3.27e-047487410GO:0048667
GeneOntologyBiologicalProcessnegative regulation of respiratory burst

GRN DUSP10

3.51e-048742GO:0060268
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by baroreceptor feedback

CHRFAM7A CHRNA7

3.51e-048742GO:0003025
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

HSPG2 CDSN NF1 LRP1 LAMB1 TNFAIP3 NOTCH4

3.93e-04375747GO:0007162
GeneOntologyBiologicalProcessnegative regulation of protein phosphorylation

NF1 APC PRKN DUSP10 TNFAIP3 CHRFAM7A CHRNA7

3.93e-04375747GO:0001933
GeneOntologyBiologicalProcesspositive regulation of epithelial cell proliferation

SOX9 HSPG2 NF1 LAMB1 GRN TNFAIP3

4.19e-04270746GO:0050679
GeneOntologyBiologicalProcesspositive regulation of CoA-transferase activity

CHRFAM7A CHRNA7

4.50e-049742GO:1905920
GeneOntologyBiologicalProcessnegative regulation of neurotransmitter secretion

NF1 PRKN

4.50e-049742GO:0046929
GeneOntologyBiologicalProcessregulation of ERK1 and ERK2 cascade

MT3 NF1 LRP1 DUSP15 DUSP10 CHRFAM7A CHRNA7

4.59e-04385747GO:0070372
GeneOntologyBiologicalProcessastrocyte differentiation

SOX9 NF1 LRP1 GRN

5.55e-04105744GO:0048708
GeneOntologyBiologicalProcessnegative regulation of phosphorylation

NF1 APC PRKN DUSP10 TNFAIP3 CHRFAM7A CHRNA7

5.85e-04401747GO:0042326
GeneOntologyBiologicalProcessneuron projection development

HSPG2 MT3 NF1 HECW2 SLIT1 LRP1 APC LAMA3 LAMB1 PRKN GRN CHRFAM7A CHRNA7

5.96e-0412857413GO:0031175
GeneOntologyBiologicalProcessneuron development

MYT1L HSPG2 MT3 NF1 HECW2 SLIT1 LRP1 APC LAMA3 LAMB1 PRKN GRN CHRFAM7A CHRNA7

6.23e-0414637414GO:0048666
GeneOntologyBiologicalProcessastrocyte development

NF1 LRP1 GRN

6.42e-0447743GO:0014002
GeneOntologyBiologicalProcesscell junction organization

NF1 ANK2 CD177 SLIT1 LRP1 APC LAMA3 GRN NRG3 CHRFAM7A CHRNA7

6.72e-049747411GO:0034330
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

GRN DUSP10

6.84e-0411742GO:0060264
GeneOntologyBiologicalProcessregulation of CoA-transferase activity

CHRFAM7A CHRNA7

6.84e-0411742GO:1905918
GeneOntologyBiologicalProcessbehavioral response to nicotine

CHRFAM7A CHRNA7

6.84e-0411742GO:0035095
GeneOntologyBiologicalProcessnegative regulation of protein serine/threonine kinase activity

NF1 APC DUSP10 TNFAIP3

7.08e-04112744GO:0071901
GeneOntologyBiologicalProcessregulation of angiogenesis

HSPG2 NF1 GRN TNFAIP3 FUT1 CHRNA7 NOTCH4

7.68e-04420747GO:0045765
GeneOntologyBiologicalProcessnegative regulation of interleukin-1 beta production

TNFAIP3 CHRFAM7A CHRNA7

7.70e-0450743GO:0032691
GeneOntologyBiologicalProcessregulation of developmental growth

MT3 SLIT1 LRP1 APC PRKN GRN DUSP10

7.79e-04421747GO:0048638
GeneOntologyBiologicalProcessepithelial cell proliferation involved in prostate gland development

SOX9 APC

8.19e-0412742GO:0060767
GeneOntologyBiologicalProcessregulation of synapse structural plasticity

CHRFAM7A CHRNA7

8.19e-0412742GO:0051823
GeneOntologyBiologicalProcessregulation of vasculature development

HSPG2 NF1 GRN TNFAIP3 FUT1 CHRNA7 NOTCH4

8.82e-04430747GO:1901342
GeneOntologyBiologicalProcessepithelial cell migration

SOX9 NF1 APC GRN DUSP10 FUT1 MACIR

9.06e-04432747GO:0010631
GeneOntologyBiologicalProcessepithelium migration

SOX9 NF1 APC GRN DUSP10 FUT1 MACIR

9.43e-04435747GO:0090132
GeneOntologyBiologicalProcessgliogenesis

SOX9 NF1 LRP1 LAMB1 GRN DUSP15 DUSP10

9.43e-04435747GO:0042063
GeneOntologyBiologicalProcesssubstrate-independent telencephalic tangential migration

SLIT1 NRG3

9.65e-0413742GO:0021826
GeneOntologyBiologicalProcesssubstrate-independent telencephalic tangential interneuron migration

SLIT1 NRG3

9.65e-0413742GO:0021843
GeneOntologyBiologicalProcessregulation of Schwann cell migration

NF1 LRP1

9.65e-0413742GO:1900147
GeneOntologyBiologicalProcessregulation of synaptic transmission, dopaminergic

CHRFAM7A CHRNA7

9.65e-0413742GO:0032225
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

GRN DUSP10

9.65e-0413742GO:0002536
GeneOntologyBiologicalProcesslearning

NF1 PRKN LRRN4 CHRFAM7A CHRNA7

9.92e-04212745GO:0007612
GeneOntologyBiologicalProcesstissue migration

SOX9 NF1 APC GRN DUSP10 FUT1 MACIR

1.02e-03441747GO:0090130
GeneOntologyBiologicalProcessglial cell differentiation

SOX9 NF1 LRP1 GRN DUSP15 DUSP10

1.03e-03321746GO:0010001
GeneOntologyBiologicalProcesscentral nervous system development

SOX9 HSPG2 NF1 SLIT1 LRP1 LAMB1 PRKN GRN DUSP15 DUSP10 FUT1 NRG3

1.07e-0311977412GO:0007417
GeneOntologyBiologicalProcessnegative regulation of developmental growth

MT3 SLIT1 APC DUSP10

1.10e-03126744GO:0048640
GeneOntologyBiologicalProcessSchwann cell migration

NF1 LRP1

1.12e-0314742GO:0036135
GeneOntologyBiologicalProcessnegative regulation of neurotransmitter transport

NF1 PRKN

1.12e-0314742GO:0051589
GeneOntologyBiologicalProcessresponse to food

MT3 CHRFAM7A CHRNA7

1.19e-0358743GO:0032094
GeneOntologyBiologicalProcessregulation of oligodendrocyte differentiation

NF1 DUSP15 DUSP10

1.19e-0358743GO:0048713
GeneOntologyBiologicalProcessassociative learning

NF1 LRRN4 CHRFAM7A CHRNA7

1.23e-03130744GO:0008306
GeneOntologyCellularComponentspine apparatus membrane

CHRFAM7A CHRNA7

3.70e-053742GO:0098897
GeneOntologyCellularComponentinterphotoreceptor matrix

EYS RTBDN

1.84e-046742GO:0033165
GeneOntologyCellularComponentspine apparatus

CHRFAM7A CHRNA7

4.38e-049742GO:0097444
GeneOntologyCellularComponentexternal side of plasma membrane

MPL STAB2 LRP1 ASTN1 RTBDN CHRFAM7A MILR1 CHRNA7

4.90e-04519748GO:0009897
GeneOntologyCellularComponentlaminin complex

LAMA3 LAMB1

5.46e-0410742GO:0043256
GeneOntologyCellularComponentside of membrane

MPL STAB2 ANK2 CD177 LRP1 ASTN1 RTBDN CHRFAM7A MILR1 CHRNA7

9.94e-048757410GO:0098552
MousePhenoabnormal spatial learning

NF1 KANSL1 ANK2 PRKN GRN LRRN4 CHRFAM7A CHRNA7

1.14e-05276558MP:0001463
MousePhenoairway basal cell hyperplasia

CHRFAM7A CHRNA7

1.52e-052552MP:0011115
MousePhenoabnormal airway basal cell differentiation

CHRFAM7A CHRNA7

1.52e-052552MP:0011114
MousePhenoabnormal airway basal cell morphology

CHRFAM7A CHRNA7

1.52e-052552MP:0011113
MousePhenoincreased fibroma incidence

NF1 APC

9.07e-054552MP:0003580
MousePhenoabnormal nicotine-mediated receptor currents

CHRFAM7A CHRNA7

9.07e-054552MP:0009475
DomainEGF_1

HSPG2 EYS STAB2 SLIT1 LRP1 LAMA3 LAMB1 ASTN1 NRG3 SSPOP NOTCH4

4.18e-092557311PS00022
DomainEGF_2

HSPG2 EYS STAB2 SLIT1 LRP1 LAMA3 LAMB1 ASTN1 NRG3 SSPOP NOTCH4

6.24e-092657311PS01186
DomainEGF

HSPG2 EYS STAB2 SLIT1 LRP1 LAMA3 LAMB1 ASTN1 NRG3 NOTCH4

2.55e-082357310SM00181
DomainEGF-like_dom

HSPG2 EYS STAB2 SLIT1 LRP1 LAMA3 LAMB1 ASTN1 NRG3 NOTCH4

4.41e-082497310IPR000742
DomainEGF-like_CS

HSPG2 EYS STAB2 SLIT1 LRP1 LAMA3 LAMB1 ASTN1 NRG3 NOTCH4

6.85e-082617310IPR013032
DomainGrowth_fac_rcpt_

HSPG2 EYS STAB2 SLIT1 LRP1 LAMA3 LAMB1 NOTCH4

1.68e-07156738IPR009030
DomainEGF_3

HSPG2 EYS STAB2 SLIT1 LRP1 ASTN1 NRG3 SSPOP NOTCH4

3.27e-07235739PS50026
DomainEGF

HSPG2 EYS STAB2 SLIT1 LRP1 NRG3 NOTCH4

6.06e-07126737PF00008
DomainEGF_LAM_2

HSPG2 STAB2 LAMA3 LAMB1

5.45e-0630734PS50027
DomainEGF_LAM_1

HSPG2 STAB2 LAMA3 LAMB1

5.45e-0630734PS01248
DomainEGF_CA

HSPG2 EYS STAB2 SLIT1 LRP1 NOTCH4

8.17e-06122736SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 EYS STAB2 SLIT1 LRP1 NOTCH4

8.98e-06124736IPR001881
DomainEGF_Lam

HSPG2 STAB2 LAMA3 LAMB1

1.03e-0535734SM00180
DomainLAM_G_DOMAIN

HSPG2 EYS SLIT1 LAMA3

1.43e-0538734PS50025
DomainLaminin_EGF

HSPG2 STAB2 LAMA3 LAMB1

1.43e-0538734IPR002049
DomainLaminin_G_2

HSPG2 EYS SLIT1 LAMA3

1.76e-0540734PF02210
DomainLamG

HSPG2 EYS SLIT1 LAMA3

2.59e-0544734SM00282
DomainVWD

SUSD2 SSPOP MUC5AC

3.09e-0516733SM00216
DomainVWF_type-D

SUSD2 SSPOP MUC5AC

3.09e-0516733IPR001846
DomainVWFD

SUSD2 SSPOP MUC5AC

3.09e-0516733PS51233
DomainVWD

SUSD2 SSPOP MUC5AC

3.09e-0516733PF00094
Domain-

HSPG2 EYS SLIT1 LAMA3 ADGRG4

3.50e-05957352.60.120.200
DomainCTCK_1

SLIT1 SSPOP MUC5AC

4.48e-0518733PS01185
DomainKeratin_matx

KRTAP3-3 KRTAP3-2

4.51e-053732PF04579
DomainLaminin_G

HSPG2 EYS SLIT1 LAMA3

7.77e-0558734IPR001791
DomainKeratin_matx

KRTAP3-3 KRTAP3-2

9.00e-054732PD010562
DomainCys_knot_C

SLIT1 SSPOP MUC5AC

1.24e-0425733IPR006207
DomainCTCK_2

SLIT1 SSPOP MUC5AC

1.24e-0425733PS01225
DomainKeratin_matx

KRTAP3-3 KRTAP3-2

1.50e-045732IPR007659
DomainhEGF

EYS SLIT1 NOTCH4

1.75e-0428733PF12661
DomainConA-like_dom

HSPG2 EYS SLIT1 LAMA3 TRIM34 ADGRG4

2.15e-04219736IPR013320
DomainMob1_phocein

MOB3C MOB3A

3.12e-047732PF03637
DomainMOB_kinase_act_fam

MOB3C MOB3A

3.12e-047732IPR005301
Domain-

MOB3C MOB3A

3.12e-0477321.20.140.30
DomainMob1_phocein

MOB3C MOB3A

3.12e-047732SM01388
DomainLaminin_EGF

HSPG2 LAMA3 LAMB1

3.43e-0435733PF00053
DomainLAMININ_IVA

HSPG2 LAMA3

4.16e-048732PS51115
DomainLaminin_B

HSPG2 LAMA3

4.16e-048732PF00052
DomainLamB

HSPG2 LAMA3

4.16e-048732SM00281
DomainLaminin_IV

HSPG2 LAMA3

4.16e-048732IPR000034
DomainLDLR_class-A_CS

HSPG2 LRP1 SSPOP

5.10e-0440733IPR023415
DomainEGF_Ca-bd_CS

EYS SLIT1 LRP1 NOTCH4

5.66e-0497734IPR018097
DomainEGF_CA

EYS SLIT1 LRP1 NOTCH4

6.11e-0499734PS01187
DomainLdl_recept_a

HSPG2 LRP1 SSPOP

7.23e-0445733PF00057
Domain-

HSPG2 LRP1 SSPOP

7.71e-04467334.10.400.10
DomainEGF-type_Asp/Asn_hydroxyl_site

EYS SLIT1 LRP1 NOTCH4

7.90e-04106734IPR000152
DomainLaminin_G_1

HSPG2 EYS

8.10e-0411732PF00054
DomainLDLRA_1

HSPG2 LRP1 SSPOP

8.73e-0448733PS01209
DomainLDLRA_2

HSPG2 LRP1 SSPOP

9.28e-0449733PS50068
DomainLDrepeatLR_classA_rpt

HSPG2 LRP1 SSPOP

9.28e-0449733IPR002172
DomainLDLa

HSPG2 LRP1 SSPOP

9.28e-0449733SM00192
DomainTIL

SSPOP MUC5AC

9.70e-0412732PF01826
DomainC8

SSPOP MUC5AC

9.70e-0412732PF08742
DomainUnchr_dom_Cys-rich

SSPOP MUC5AC

1.14e-0313732IPR014853
DomainC8

SSPOP MUC5AC

1.14e-0313732SM00832
DomainAtypical_DUSP

DUSP15 DUSP10

1.14e-0313732IPR020417
DomainTIL_dom

SSPOP MUC5AC

1.33e-0314732IPR002919
DomainFerritin-like_SF

MOB3C MOB3A

1.33e-0314732IPR009078
DomainLaminin_N

LAMA3 LAMB1

1.75e-0316732IPR008211
DomainLAMININ_NTER

LAMA3 LAMB1

1.75e-0316732PS51117
DomainLaminin_N

LAMA3 LAMB1

1.75e-0316732PF00055
DomainLamNT

LAMA3 LAMB1

1.75e-0316732SM00136
DomainVWC_out

SSPOP MUC5AC

2.47e-0319732SM00215
DomainCT

SLIT1 MUC5AC

3.31e-0322732SM00041
Domain-

CHRFAM7A CHRNA7

3.61e-03237321.20.120.370
DomainAcetylcholine_rcpt_TM

CHRFAM7A CHRNA7

3.61e-0323732IPR027361
DomainFN3

MPL FNDC7 ASTN1 LRRN4

5.96e-03185734SM00060
Pubmed

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.

MYF5 HSPG2 LAMB1

1.14e-061075316554364
Pubmed

Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.

MYF5 HSPG2 LAMB1

3.45e-061475319783738
Pubmed

Basement membrane composition in the early mouse embryo day 7.

HSPG2 LAMA3 LAMB1

4.30e-061575315895400
Pubmed

Microtubule-dependent apical polarization of basement membrane matrix mRNAs in mouse epithelial cells.

SOX9 HSPG2 LAMB1

4.30e-061575338103869
Pubmed

Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.

CHRFAM7A CHRNA7

4.59e-06275238070724
Pubmed

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.

CHRFAM7A CHRNA7

4.59e-06275234453977
Pubmed

Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

CHRFAM7A CHRNA7

4.59e-06275226999808
Pubmed

Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.

CHRFAM7A CHRNA7

4.59e-06275227129924
Pubmed

Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.

CHRFAM7A CHRNA7

4.59e-06275223521765
Pubmed

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.

CHRFAM7A CHRNA7

4.59e-06275228258105
Pubmed

The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.

CHRFAM7A CHRNA7

4.59e-06275219344760
Pubmed

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.

CHRFAM7A CHRNA7

4.59e-06275229114104
Pubmed

Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.

CHRFAM7A CHRNA7

4.59e-06275233995108
Pubmed

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.

CHRFAM7A CHRNA7

4.59e-06275232552811
Pubmed

Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.

CHRFAM7A CHRNA7

4.59e-06275224836856
Pubmed

Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.

CHRFAM7A CHRNA7

4.59e-06275215948184
Pubmed

Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.

CHRFAM7A CHRNA7

4.59e-06275235678315
Pubmed

Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.

CHRFAM7A CHRNA7

4.59e-06275212628457
Pubmed

Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.

CHRFAM7A CHRNA7

4.59e-06275225157794
Pubmed

Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.

CHRFAM7A CHRNA7

4.59e-06275231202708
Pubmed

Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.

CHRFAM7A CHRNA7

4.59e-06275222246862
Pubmed

Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.

CHRFAM7A CHRNA7

4.59e-06275227471776
Pubmed

Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.

CHRFAM7A CHRNA7

4.59e-06275222688057
Pubmed

Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.

CHRFAM7A CHRNA7

4.59e-06275232028688
Pubmed

Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.

CHRFAM7A CHRNA7

4.59e-06275230429582
Pubmed

A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.

CHRFAM7A CHRNA7

4.59e-06275221501254
Pubmed

Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.

CHRFAM7A CHRNA7

4.59e-06275221368056
Pubmed

Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.

CHRFAM7A CHRNA7

4.59e-0627521400473
Pubmed

PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.

APC PRKN

4.59e-06275220696900
Pubmed

Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.

CHRFAM7A CHRNA7

4.59e-06275226937017
Pubmed

Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.

CHRFAM7A CHRNA7

4.59e-06275236603528
Pubmed

Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.

CHRFAM7A CHRNA7

4.59e-06275226650489
Pubmed

Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.

CHRFAM7A CHRNA7

4.59e-06275222848433
Pubmed

Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.

CHRFAM7A CHRNA7

4.59e-06275216650968
Pubmed

Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.

CHRFAM7A CHRNA7

4.59e-06275235413868
Pubmed

Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.

CHRFAM7A CHRNA7

4.59e-06275224462939
Pubmed

Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.

CHRFAM7A CHRNA7

4.59e-06275229261717
Pubmed

Specific glycoforms of MUC5AC and endorepellin accurately distinguish mucinous from nonmucinous pancreatic cysts.

HSPG2 MUC5AC

4.59e-06275223836919
Pubmed

Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.

CHRFAM7A CHRNA7

4.59e-06275218199426
Pubmed

Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.

CHRFAM7A CHRNA7

4.59e-06275222490926
Pubmed

Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.

CHRFAM7A CHRNA7

4.59e-06275223270857
Pubmed

Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.

CHRFAM7A CHRNA7

4.59e-06275218077004
Pubmed

Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.

CHRFAM7A CHRNA7

4.59e-06275219462340
Pubmed

Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.

CHRFAM7A CHRNA7

4.59e-06275216923147
Pubmed

NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.

CHRFAM7A CHRNA7

4.59e-06275211790782
Pubmed

Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.

CHRFAM7A CHRNA7

4.59e-06275237746145
Pubmed

A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

CHRFAM7A CHRNA7

4.59e-06275219631623
Pubmed

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

CHRFAM7A CHRNA7

4.59e-06275215770102
Pubmed

Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.

CHRFAM7A CHRNA7

4.59e-06275224326163
Pubmed

Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.

CHRFAM7A CHRNA7

4.59e-06275223811428
Pubmed

Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.

CHRFAM7A CHRNA7

4.59e-06275220720594
Pubmed

Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.

CHRFAM7A CHRNA7

4.59e-06275217019565
Pubmed

Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.

CHRFAM7A CHRNA7

4.59e-06275219100751
Pubmed

Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.

CHRFAM7A CHRNA7

4.59e-06275235883638
Pubmed

Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.

CHRFAM7A CHRNA7

4.59e-06275219368846
Pubmed

Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones.

CHRFAM7A CHRNA7

4.59e-06275215009674
Pubmed

Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression.

CHRFAM7A CHRNA7

4.59e-06275238253622
Pubmed

The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.

CHRFAM7A CHRNA7

4.59e-06275234514543
Pubmed

α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.

CHRFAM7A CHRNA7

4.59e-06275222183893
Pubmed

Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents.

CHRFAM7A CHRNA7

4.59e-0627529364063
Pubmed

Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.

CHRFAM7A CHRNA7

4.59e-06275212606407
Pubmed

Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia.

CHRFAM7A CHRNA7

4.59e-06275222300029
Pubmed

GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice.

CHRFAM7A CHRNA7

4.59e-06275232018068
Pubmed

CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders.

CHRFAM7A CHRNA7

4.59e-06275226206074
Pubmed

Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.

CHRFAM7A CHRNA7

4.59e-06275224349346
Pubmed

The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.

CHRFAM7A CHRNA7

4.59e-06275221143250
Pubmed

Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.

CHRFAM7A CHRNA7

4.59e-06275216319313
Pubmed

Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.

CHRFAM7A CHRNA7

4.59e-06275225797465
Pubmed

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.

CHRFAM7A CHRNA7

4.59e-06275229197398
Pubmed

Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.

CHRFAM7A CHRNA7

4.59e-06275238178134
Pubmed

In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.

CHRFAM7A CHRNA7

4.59e-06275223325242
Pubmed

Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.

CHRFAM7A CHRNA7

4.59e-06275222649244
Pubmed

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.

CHRFAM7A CHRNA7

4.59e-06275217898229
Pubmed

Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.

CHRFAM7A CHRNA7

4.59e-06275221901321
Pubmed

Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors.

CHRFAM7A CHRNA7

4.59e-06275217935702
Pubmed

Somatic NF1 inactivation is a frequent event in sporadic pheochromocytoma.

SOX9 NF1

4.59e-06275222962301
Pubmed

Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.

CHRFAM7A CHRNA7

4.59e-06275220624304
Pubmed

Cytokine-induced alterations of α7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis.

CHRFAM7A CHRNA7

4.59e-06275221784975
Pubmed

Lack of acetylcholine nicotine alpha 7 receptor suppresses development of collagen-induced arthritis and adaptive immunity.

CHRFAM7A CHRNA7

4.59e-06275220659128
Pubmed

Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.

CHRFAM7A CHRNA7

4.59e-06275220843956
Pubmed

Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth.

CHRFAM7A CHRNA7

4.59e-06275210800961
Pubmed

Characterization of allelic variants at chromosome 15q14 in schizophrenia.

CHRFAM7A CHRNA7

4.59e-06275216417613
Pubmed

Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.

CHRFAM7A CHRNA7

4.59e-06275211834293
Pubmed

Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.

CHRFAM7A CHRNA7

4.59e-06275222314319
Pubmed

Antagonism of Cerebral High Mobility Group Box 1 Ameliorates Dendritic Cell Dysfunction in Sepsis.

CHRFAM7A CHRNA7

4.59e-06275234512319
Pubmed

Visual acuity is reduced in alpha 7 nicotinic receptor knockout mice.

CHRFAM7A CHRNA7

4.59e-06275222281823
Pubmed

Activation of α7-nAChRs Promotes the Clearance of α-Synuclein and Protects Against Apoptotic Cell Death Induced by Exogenous α-Synuclein Fibrils.

CHRFAM7A CHRNA7

4.59e-06275233718373
Pubmed

Nicotinic receptor involvement in regulation of functions of mouse neutrophils from inflammatory site.

CHRFAM7A CHRNA7

4.59e-06275226965141
Pubmed

A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication.

CHRFAM7A CHRNA7

4.59e-06275227676657
Pubmed

Central role of alpha7 nicotinic receptor in differentiation of the stratified squamous epithelium.

CHRFAM7A CHRNA7

4.59e-06275212391028
Pubmed

Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice.

CHRFAM7A CHRNA7

4.59e-06275225365546
Pubmed

α7 Nicotinic Acetylcholine Receptor Regulates the Function and Viability of L Cells.

CHRFAM7A CHRNA7

4.59e-06275229992246
Pubmed

Mouse muscle denervation increases expression of an alpha7 nicotinic receptor with unusual pharmacology.

CHRFAM7A CHRNA7

4.59e-06275212562921
Pubmed

NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.

NF1 RGS9

4.59e-06275227773571
Pubmed

CHRFAM7A expression in mice increases resiliency after injury.

CHRFAM7A CHRNA7

4.59e-06275234792616
Pubmed

An ovarian phenotype of alpha 7 nicotinic receptor knockout mice.

CHRFAM7A CHRNA7

4.59e-06275237432973
Pubmed

Altered baroreflex responses in alpha7 deficient mice.

CHRFAM7A CHRNA7

4.59e-06275210942027
Pubmed

Stimulation of toll-like receptor 4 downregulates the expression of α7 nicotinic acetylcholine receptors via histone deacetylase in rodent microglia.

CHRFAM7A CHRNA7

4.59e-06275232413437
Pubmed

Astrocytic α7 Nicotinic Receptor Activation Inhibits Amyloid-β Aggregation by Upregulating Endogenous αB-crystallin through the PI3K/Akt Signaling Pathway.

CHRFAM7A CHRNA7

4.59e-06275230345917
Pubmed

Alpha7 nicotinic acetylcholine receptor expression in Alzheimer's disease: receptor densities in brain regions of the APP(SWE) mouse model and in human peripheral blood lymphocytes.

CHRFAM7A CHRNA7

4.59e-06275217192639
Cytoband17q12-q21

KRTAP3-3 KRTAP3-2 KRT38 KRT37

2.28e-073275417q12-q21
CytobandEnsembl 112 genes in cytogenetic band chr17q21

KANSL1 KRTAP3-3 KRTAP3-2 GRN KRT38 KRT37

1.28e-04473756chr17q21
GeneFamilyMOB kinase activators|STRIPAK complex

MOB3C MOB3A

1.44e-047482647
GeneFamilyLaminin subunits

LAMA3 LAMB1

4.48e-0412482626
GeneFamilyFibronectin type III domain containing

MPL FNDC7 ASTN1 LRRN4

8.49e-04160484555
GeneFamilyKeratins, type I

KRT38 KRT37

2.50e-0328482608
CoexpressionDING_LUNG_CANCER_MUTATED_FREQUENTLY

NF1 APC NOTCH4

4.86e-0612753M16718
CoexpressionNABA_CORE_MATRISOME

HSPG2 EYS FNDC7 SLIT1 LAMA3 LAMB1 SSPOP

1.40e-05275757M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

EYS FNDC7 SLIT1 LAMA3 LAMB1 SSPOP

2.12e-05196756M3008
CoexpressionGSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN

MYT1L MT3 NF1 SLIT1 NRG3 ZNF786

2.38e-05200756M7473
CoexpressionDESCARTES_FETAL_LIVER_VASCULAR_ENDOTHELIAL_CELLS

HSPG2 STAB2 HECW2 CHRNA7 NOTCH4

5.91e-05144755M40230
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

HSPG2 STAB2 ARHGAP31 HECW2 NRG3 NOTCH4

9.93e-07196756e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 MT3 CCDC190 LRP1 MUC5AC

6.26e-061547555ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 HECW2 RGS9 NRG3 NOTCH4

6.46e-061557555d157478669b609e1f0f0a75afd0112571fc2c46
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

KCTD19 HECW2 FUT1 NRG3 NOTCH4

9.28e-061677555af9127bae05768a5164d5708a4ad37edca99324
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

C4orf17 HECW2 FUT1 NRG3 NOTCH4

1.04e-05171755bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 STAB2 LAMB1 FUT1 NOTCH4

1.56e-05186755e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 ANK2 SUSD2 LAMA3 TNFAIP1

1.60e-05187755f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 ARHGAP31 HECW2 TNFAIP1 NOTCH4

1.64e-05188755a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 NOTCH4

1.73e-05190755a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ARHGAP31 HECW2 LAMA3 LAMB1

1.73e-051907559d5242759546be0089981ef1877e4ed5f81face5
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ARHGAP31 HECW2 LAMA3 NOTCH4

1.73e-05190755b7fc451e160e31dc898b122de844b501f587db67
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 NOTCH4

1.73e-0519075525525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ARHGAP31 HECW2 LAMA3 NOTCH4

1.73e-0519075583cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ARHGAP31 HECW2 LAMA3 NOTCH4

1.73e-051907555f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 LAMA3 TNFAIP3 NOTCH4

1.82e-051927553259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NRG3 NOTCH4

1.91e-05194755f76808666fb875fc787751cbfd924d9be20a8192
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NRG3 NOTCH4

1.91e-05194755f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NRG3 NOTCH4

1.91e-05194755a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 TNFAIP1

1.96e-05195755f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 TNFAIP1

1.96e-05195755ea1b00805391dca8be0883b635768b296369919a
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 TNFAIP1

1.96e-05195755126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 TNFAIP1

1.96e-0519575585df110f753f58ab017018c54ee454edb4428e29
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SUSD2 LAMA3 LRRN4 TMEM125

1.96e-0519575568f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellbackground-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

HSPG2 STAB2 ARHGAP31 HECW2 NRG3

1.96e-05195755c7d60dabfc7cb310e002cab10003dadfcc34fe33
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KCTD19 GRN FOXN3 CHRFAM7A NOTCH4

1.96e-05195755cb27f6ca8b02438c353c9dff2f76d2656bb5b29a
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SUSD2 LAMA3 LRRN4 TMEM125

1.96e-051957552a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP31 HECW2 RGS9 NRG3 NOTCH4

2.01e-0519675549cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NRG3 NOTCH4

2.01e-05196755d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 TNFAIP1

2.01e-0519675581900dcc9451ff6606ec940c16b559d73247590e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SUSD2 LAMA3 LRRN4 TMEM125

2.01e-05196755eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 TNFAIP1

2.06e-05197755d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SUSD2 LAMA3 LRRN4 TMEM125

2.06e-05197755c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 ARHGAP31 HECW2 TNFAIP1

2.06e-05197755412091994196a06c2779b4c2cfed84be889a5f8d
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 ARHGAP31 HECW2 LAMB1 NOTCH4

2.06e-05197755b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SUSD2 LAMA3 LRRN4 TMEM125

2.06e-05197755734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SUSD2 LAMA3 LRRN4 TMEM125

2.06e-05197755e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 MYF5 HSPG2 LAMB1 DUSP10

2.11e-051987555e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCell18-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

HSPG2 STAB2 HECW2 TNFAIP1 NOTCH4

2.11e-0519875570d3ea0837dd6ad62abdf349e566a2e62c8e345a
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 STAB2 HECW2 LAMB1 NOTCH4

2.11e-051987552630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 STAB2 HECW2 LAMB1 NOTCH4

2.11e-051987551e83bec16dcd60460422625f89952ff506d6be51
ToppCell18-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

HSPG2 STAB2 HECW2 TNFAIP1 NOTCH4

2.11e-051987556b7f1b352dc3a803af87106ffb63944bd4286dfe
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 STAB2 ARHGAP31 HECW2 NOTCH4

2.16e-05199755f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

EYS HEATR5A RGS9 LRRN4

7.99e-051357543351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 LAMA3 NOTCH4

8.94e-05139754b07929348ec9ad95d7bce33a7deac0938227b19f
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 KCTD19 HECW2

1.36e-041557548fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC7 MT3 ARHGAP31 HECW2

1.36e-0415575459035d792c26d870a8b097939e97fa47859ba68c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 FNDC7 ARHGAP31 NOTCH4

1.40e-04156754ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 FNDC7 ARHGAP31 NOTCH4

1.40e-04156754586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUSD2 CCDC190 LAMA3 TMEM125

1.43e-041577549665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCellnormal_Pleural_Fluid-T/NK_cells-CD4+_Th|normal_Pleural_Fluid / Location, Cell class and cell subclass

ANK2 ASTN1 TNFAIP3 SLC26A11

1.50e-04159754ebd840ac2b07e62086ee7b5bb01c21804a0fdc7b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HECW2 CCDC190 NRG3 ADGRG4

1.50e-04159754d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 CD177 DUSP15 FUT1

1.58e-041617540d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 CDSN FNDC7 FUT1

1.61e-041627543dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 CDSN FNDC7 FUT1

1.61e-041627540a7138266054ea5954649c8b61ef93905d56b068
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 CDSN FNDC7 FUT1

1.61e-0416275425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellnormal_Pleural_Fluid-T/NK_cells-CD4+_Th|T/NK_cells / Location, Cell class and cell subclass

ANK2 ASTN1 GRN TNFAIP3

1.69e-04164754334f376350c9cf92611d0f75b2e18a102f4c116a
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

KCTD19 LRRN4 FUT1 MUC5AC

1.81e-04167754892a2dc83ab5de5a1016402f8e95d2aabf651326
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

STAB2 RGS9 TNFAIP3 LRRN4

1.85e-0416875407be11b6f0f37106e219692db5795c6dd32807c9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 HECW2 NRG3 NOTCH4

1.90e-04169754987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 CDSN ARHGAP31 NOTCH4

1.90e-04169754c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SUSD2 LAMA3 LRRN4

1.90e-04169754cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 ARHGAP31 HECW2 NOTCH4

1.98e-04171754b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCellInfluenza_Severe-B_intermediate|World / Disease group and Cell class

EYS ANK2 CCDC190 DUSP15

1.98e-041717544d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 CD177 ARHGAP31

2.03e-04172754a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 HECW2 NRG3 NOTCH4

2.07e-04173754f193c63cc536d891c9d23043765e320252bb6e65
ToppCelldroplet-Fat-SCAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPL ARHGAP31 TNFAIP1 NOTCH4

2.07e-04173754eb58b0189e71e38d4f4f1cf544a82cde8d1c86bc
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 KCTD19 HECW2 FUT1

2.12e-0417475442735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

ANK2 KCTD19 LAMA3 RTBDN

2.17e-041757549a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 CD177 ARHGAP31

2.21e-041767543494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 SUSD2 LAMA3 TNFAIP1

2.21e-041767544a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 HECW2 NRG3 NOTCH4

2.21e-04176754dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 STAB2 CD177 ARHGAP31

2.21e-04176754d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

HSPG2 STAB2 HECW2 NOTCH4

2.26e-04177754f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 SUSD2 LAMA3 HEATR5A

2.26e-041777549af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYS ANK2 KRTAP3-3 RTBDN

2.36e-04179754878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NOTCH4

2.36e-041797548f9e538c822940785130297712b75131812a4603
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

ARHGAP31 HECW2 NRG3 NOTCH4

2.41e-04180754b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 SUSD2 LAMA3 TMEM125

2.41e-041807542d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HSPG2 EYS NRG3 NOTCH4

2.41e-041807545861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

HECW2 FUT1 NRG3 NOTCH4

2.46e-0418175461608123959483ff60f07d8467996853c4371b6a
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ZNF821 STAB2 HECW2

2.46e-041817544df7972f88117108698efd06b124b232f8588981
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 SUSD2 LAMA3 HEATR5A

2.46e-04181754b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L ANK2 SLIT1 CHRFAM7A

2.46e-041817547f99002a6411117cc2361334c7c9228e20c574b4
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HSPG2 HECW2 NRG3 NOTCH4

2.46e-041817542c660fcf0404c155955b67ab2958d6e6b0e30024
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ZNF821 STAB2 HECW2

2.46e-04181754cbb530566893281289026bfd93adf721decd4ca3
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 ARHGAP31 HECW2 TNFAIP3

2.52e-0418275463b41b538b26bc899558807fd035e543611f8c52
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ARHGAP31 HECW2 NOTCH4

2.52e-04182754dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

HECW2 RGS9 NRG3 NOTCH4

2.52e-04182754a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 ARHGAP31 HECW2 NOTCH4

2.52e-04182754010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell390C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|390C / Donor, Lineage, Cell class and subclass (all cells)

MT3 ANK2 TRIM34 ADGRG4

2.57e-0418375428e1fc6498aaf8f42c4d6d4fa54ffff4c546d0d1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NOTCH4

2.57e-04183754dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NOTCH4

2.57e-041837544759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell390C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|390C / Donor, Lineage, Cell class and subclass (all cells)

MT3 ANK2 TRIM34 ADGRG4

2.57e-04183754667d9107af17fd076ceff6b2cbcb78f892fd62d2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ARHGAP31 HECW2 NOTCH4

2.62e-04184754688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SUSD2 LAMA3 LRRN4 TMEM125

2.62e-04184754ca940a4f4970285ed284d5517d142abab0682044
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDSN MT3 DUSP15 CHRNA7

2.68e-0418575411c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 HECW2 FUT1 NOTCH4

2.68e-04185754a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

HECW2 FUT1 NRG3 NOTCH4

2.68e-04185754a28187c2fd23564314b35759479ff2ca21f61485
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MT3 LAMA3 DUSP15 TMEM125

2.73e-04186754e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCelldroplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MT3 LAMA3 DUSP15 TMEM125

2.73e-041867544c0b59d845b79323e7a3287e7c4d249f5f322556
ComputationalNeighborhood of AF1Q

MYT1L ANK2 ASTN1

1.12e-0425413GNF2_AF1Q
Drugdisopyramide

GRN TNFAIP1 TNFAIP3 CHRFAM7A CHRNA7

2.59e-0666755CID000003114
Drugtropicamide

MT3 LAMA3 CHRFAM7A CHRNA7

3.64e-0632754CID000005593
DrugPempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A

HSPG2 ZNF821 NF1 ZFYVE16 DUSP10 FOXN3 FUT1

4.07e-061987576027_DN
DrugAPCP

NF1 APC

1.07e-052752CID003083759
Drugtetramisole

APC TNFAIP1 TNFAIP3 CHRFAM7A CHRNA7

1.72e-0597755CID000003913
DrugAC1L1C2F

RIT1 HSPG2 LAMA3 LAMB1 MUC5AC

3.17e-05110755CID000001711
DrugOxamniquine [21738-42-1]; Down 200; 14.4uM; MCF7; HT_HG-U133A

TYRP1 STAB2 C16orf95 APC FOXN3 CLBA1

4.01e-051917564124_DN
DrugDimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; MCF7; HT_HG-U133A

SOX9 MYF5 LRP1 APC TNFAIP3 FOXN3

4.01e-051917564791_UP
DrugPF-00562151-00 [351320-12-2]; Down 200; 10uM; PC3; HT_HG-U133A

NF1 ASTN1 TNFAIP1 TNFAIP3 FOXN3 ODF2

4.25e-051937565922_DN
DrugPhensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A

ZNF821 STAB2 NF1 C16orf95 APC FOXN3

4.63e-051967565097_UP
DrugDiphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; PC3; HT_HG-U133A

ZNF821 C16orf95 LRP1 FUT1 ODF2 CLBA1

4.63e-051967564591_DN
DrugLuteolin [491-70-3]; Up 200; 14uM; MCF7; HT_HG-U133A

SOX9 MYF5 HSPG2 NF1 C16orf95 CLBA1

4.77e-051977565004_UP
DrugDroperidol [548-73-2]; Up 200; 10.6uM; PC3; HT_HG-U133A

MPL HSPG2 NF1 C16orf95 LRP1 FOXN3

4.77e-051977564629_UP
DrugAcebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A

MYF5 ZNF821 NF1 APC DUSP10 FOXN3

4.90e-051987564976_DN
DrugParomomycin sulfate [1263-89-4]; Down 200; 5.6uM; PC3; HT_HG-U133A

ZNF821 C16orf95 FAM222B DUSP10 TNFAIP3 ODF2

4.90e-051987564595_DN
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; MCF7; HT_HG-U133A

NF1 C16orf95 APC DUSP10 ODF2 MACIR

4.90e-051987561671_UP
Diseaseschizophrenia (implicated_via_orthology)

ASTN1 NRG3 CHRFAM7A CHRNA7

2.63e-0568744DOID:5419 (implicated_via_orthology)
DiseaseGlioblastoma

NF1 APC PRKN MACIR

4.75e-0579744C0017636
DiseaseLung Neoplasms

RIT1 SOX9 TYRP1 APC PRKN CHRNA7

5.51e-05265746C0024121
DiseaseMalignant neoplasm of lung

RIT1 SOX9 TYRP1 APC PRKN CHRNA7

5.63e-05266746C0242379
DiseaseGiant Cell Glioblastoma

NF1 APC PRKN MACIR

6.04e-0584744C0334588
Diseasesystemic scleroderma

MYT1L ARHGAP31 TNFAIP3 NOTCH4

6.33e-0585744EFO_0000717
Diseasepsoriasis

TYRP1 CDSN ZFYVE16 SLIT1 TNFAIP3 NOTCH4

6.49e-05273746EFO_0000676
Diseaseorofacial cleft, sex interaction measurement

NF1 CHRFAM7A CHRNA7 NOTCH4

6.62e-0586744EFO_0008343, MONDO_0000358
DiseaseSchizophrenia

MYT1L WDR11 LRP1 APC GRN RGS9 NRG3 CHRFAM7A CHRNA7 NOTCH4

6.96e-058837410C0036341
Diseasecognitive disorder (implicated_via_orthology)

CHRFAM7A CHRNA7

9.25e-056742DOID:1561 (implicated_via_orthology)
Diseaserheumatoid arthritis (biomarker_via_orthology)

CHRFAM7A CHRNA7

9.25e-056742DOID:7148 (biomarker_via_orthology)
DiseaseIntellectual Disability

MYT1L RALGAPA1 SOX9 NF1 KANSL1 APC ASTN1

1.31e-04447747C3714756
DiseaseGlioblastoma Multiforme

NF1 APC PRKN MACIR

1.78e-04111744C1621958
DiseaseAlzheimer's disease (implicated_via_orthology)

ANK2 LRP1 NOTCH4

4.02e-0457743DOID:10652 (implicated_via_orthology)
Diseasetriacylglycerol 44:1 measurement

PRKN FOXN3

4.03e-0412742EFO_0010399
Diseasedementia (is_implicated_in)

GRN NOTCH4

4.03e-0412742DOID:1307 (is_implicated_in)
Diseasenicotine dependence (implicated_via_orthology)

CHRFAM7A CHRNA7

4.03e-0412742DOID:0050742 (implicated_via_orthology)
DiseaseAutistic Disorder

NF1 APC LAMB1 PRKN CHRNA7

5.10e-04261745C0004352
DiseaseRASopathy

RIT1 NF1

6.38e-0415742cv:C5555857
DiseaseAnilide use measurement

KANSL1 LRP1

6.38e-0415742EFO_0009938
Diseaseinterstitial lung disease

NRG3 MUC5AC NOTCH4

6.46e-0467743EFO_0004244
DiseaseMuscle hypotonia

RALGAPA1 KANSL1

8.24e-0417742C0026827
DiseaseLewy body dementia (is_marker_for)

PRKN CHRNA7

1.03e-0319742DOID:12217 (is_marker_for)
DiseaseNerve Degeneration

PRKN GRN CHRNA7

1.20e-0383743C0027746
DiseaseCarcinoma of lung

RIT1 PRKN

1.52e-0323742C0684249
Diseaseeye color

MYT1L TYRP1 EYS

1.52e-0390743EFO_0003949
DiseaseNoonan Syndrome

RIT1 NF1

1.65e-0324742C0028326
DiseaseDisorder of eye

TYRP1 EYS GRN RGS9

2.01e-03212744C0015397
Diseaseserum IgG glycosylation measurement

EYS STAB2 SLIT1 LAMB1 PRKN NRG3

2.02e-03523746EFO_0005193
Diseaselumbar disc degeneration

EYS PRKN

2.25e-0328742EFO_0004994
Diseasenon-alcoholic fatty liver disease severity measurement

C16orf95 NRG3

2.25e-0328742EFO_0008421
DiseaseDevelopmental Academic Disorder

NF1 PRKN

2.41e-0329742C1330966
Diseaseamyotrophic lateral sclerosis (is_marker_for)

MT3 GRN

2.41e-0329742DOID:332 (is_marker_for)
DiseaseLearning Disorders

NF1 PRKN

2.41e-0329742C0023186
Diseasepulmonary tuberculosis

MYT1L LAMA3

2.41e-0329742EFO_1000049
DiseaseLearning Disturbance

NF1 PRKN

2.41e-0329742C0751263
DiseaseAdult Learning Disorders

NF1 PRKN

2.41e-0329742C0751262
DiseaseLearning Disabilities

NF1 PRKN

2.41e-0329742C0751265

Protein segments in the cluster

PeptideGeneStartEntry
MSGDTCLCPASGAKP

TNFAIP1

1

Q13829
GCLKSPCTATSGPMS

ADGRG4

1546

Q8IZF6
VMCPDARSRCPDGST

GRN

206

P28799
RMCSPSPDATSGTGS

CEP78

651

Q5JTW2
PLGTCSSGSPRMTCP

CD177

331

Q8N6Q3
QPCGSKSSSSGHPCM

CDSN

446

Q15517
PSSCSMGIRSASRPG

CENPP

201

Q6IPU0
LDSTGCVCPSGLSPM

ASTN1

631

O14525
CVCPSGLSPMKDSSG

ASTN1

636

O14525
PDSGVVCGRMACSPT

CHRNA7

401

P36544
FSSKCMCSSGGPVDR

RBM48

206

Q5RL73
MCSSGGPVDRAPDSS

RBM48

211

Q5RL73
GDAMKATATSCRPCP

HSPG2

801

P98160
ECSGSMAPRGPSVTE

RGS9

541

O75916
MNMGGCSPTTCSPLS

KCTD19

256

Q17RG1
GCEAMSPSSSAAPVS

ANK2

2776

Q01484
PGTATCSERSMGASP

HECW2

431

Q9P2P5
RSLSSCCSPGQRSGM

NRG3

471

P56975
PTSPTSNCSDGMPEC

MYF5

156

P13349
EPGSTCLCTPGFMTC

EYS

1216

Q5T1H1
MPCSSVTGQCECRPG

LAMA3

546

Q16787
SSTGESCTMRGLPCG

FNDC7

501

Q5VTL7
STSSCPLGCTMAPGA

KRT37

6

O76014
CAASPSGMPTCRCPT

LRP1

4246

Q07954
DGCTEQSCPVMSGGP

MOB3A

81

Q96BX8
SSSSCPLGCTMAPGA

KRT38

6

O76015
QGPSSSPASDSGMAC

CCDC190

191

Q86UF4
MPSSSGSARSLNCGC

DUSP10

61

Q9Y6W6
CSSTPCSPMRRTVSG

MACIR

36

Q96GV9
MCSEASGTPAPGLTG

FAM222B

376

Q8WU58
PSCALCGSGSINTMP

KANSL1

631

Q7Z3B3
SAAAEMTCGTPPGAS

LAMB1

1391

P07942
MTCGTPPGASCSETE

LAMB1

1396

P07942
MDCCASRSCSVPTGP

KRTAP3-2

1

Q9BYR7
MDCCASRGCSVPTGP

KRTAP3-3

1

Q9BYR6
CETPRGCHMTSTPGS

MUC5AC

1841

P98088
MDPETCPCPSGGSCT

MT3

1

P25713
PDSGVVCGRMACSPT

CHRFAM7A

311

Q494W8
PVTMPSTGGDSCPFC

MILR1

211

Q7Z6M3
PVTPTSMCQGSSSGA

HEATR5A

1526

Q86XA9
SCRMRTESEPSCGSP

FOXN3

311

O00409
TSGAQCPPMTSATCL

DUSP15

151

Q9H1R2
PKACSTPGSCSSGMT

C4orf17

146

Q53FE4
TAGGSAVMSACCPSS

C16orf95

121

Q9H693
AVMSACCPSSSSSRP

C16orf95

126

Q9H693
TCTGPESRREVPMCS

FAM120B

391

Q96EK7
DTMCAPAAGSSGPFS

LRRN4

336

Q8WUT4
RCSETSCPVMAGGPR

MOB3C

81

Q70IA8
MSASSSGGSPRFPSC

ODF2

1

Q5BJF6
SCGDSNSICPAPSTM

RPIA

61

P49247
CLPGTAMGPNASSSC

FUT1

56

P19526
AGPCCPSEMDTTETS

RTBDN

56

Q9BSG5
PGPTADAQESCSMRC

SUSD2

21

Q9UGT4
AVTSMGGKSSCPVCG

TRIM34

46

Q9BYJ4
GPGLASRSGSCPCLM

SSPOP

4326

A2VEC9
SSCSAPCGGGTMERH

SSPOP

4776

A2VEC9
RMSGECQSPHCPGTS

PRKN

191

O60260
MSEDSAGSPCPSGSG

SOX9

26

P48436
TCPTGYTGPTCSEEM

NOTCH4

716

Q99466
GSVSSRSGECSPVPM

APC

101

P25054
MPREGGSTCTARCPD

CLBA1

56

Q96F83
LRSGMCCPDLSPVSG

TYRP1

36

P17643
PSECCSVMAGGTLTG

RALGAPA1

1041

Q6GYQ0
SETTAMKCRSPGCPF

TNFAIP3

471

P21580
MDSGTRPVGSCCSSP

RIT1

1

Q92963
ARSSGPGMAPSACCC

SLC26A11

11

Q86WA9
CESSVCGEVGMGPSS

ZNF627

101

Q7L945
SMDSAAGCSGTPPIC

NF1

666

P21359
SEMDPCTGLTPGGCS

STAB2

866

Q8WWQ8
CMCEGPTLSPEPGSS

ARHGAP31

1281

Q2M1Z3
VCPPMAESGSCCTTH

MPL

606

P40238
MPCGRTESGCAPTSG

RNF168

346

Q8IYW5
EGPCSCSECGERSPM

ZNF786

366

Q8N393
MCPVCGRALSSPGSL

ZNF821

151

O75541
SARIPPDGSMGSITC

WDR11

701

Q9BZH6
RVPTCTLSSGSCPAM

SLIT1

271

O75093
GVSGHCPSICMATPS

TMEM125

171

Q96AQ2
MASASCSPGGALASP

PSPHP1

1

O15172
VPSSLSCLPASGSMC

ZFYVE16

371

Q7Z3T8
KTEGMSCPTPGCDGS

MYT1L

1001

Q9UL68