Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carbonate dehydratase activity	CA13 CA1 CA2 CA7	4.63e-07	16	82	4	GO:0004089
GeneOntologyMolecularFunction	cyanamide hydratase activity	CA1 CA2	1.67e-05	2	82	2	GO:0018820
GeneOntologyMolecularFunction	glycogen synthase activity, transferring glucose-1-phosphate	GYS1 GYS2	1.67e-05	2	82	2	GO:0061547
GeneOntologyMolecularFunction	glycerol kinase activity	GK GK2	4.98e-05	3	82	2	GO:0004370
GeneOntologyMolecularFunction	alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity	GYS1 GYS2	4.98e-05	3	82	2	GO:0004373
GeneOntologyMolecularFunction	hydro-lyase activity	CA13 CA1 CA2 CA7	1.31e-04	63	82	4	GO:0016836
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA1D CACNA2D1	1.65e-04	5	82	2	GO:0086007
GeneOntologyMolecularFunction	calcium channel activity	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	1.91e-04	129	82	5	GO:0005262
GeneOntologyMolecularFunction	arylesterase activity	CA1 CA2	2.47e-04	6	82	2	GO:0004064
GeneOntologyMolecularFunction	carbon-oxygen lyase activity	CA13 CA1 CA2 CA7	3.62e-04	82	82	4	GO:0016835
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	3.95e-04	151	82	5	GO:0015085
GeneOntologyMolecularFunction	frizzled binding	CCDC88C DVL2 RNF43	6.83e-04	42	82	3	GO:0005109
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1D CACNA2D1 CACNG6	8.92e-04	46	82	3	GO:0005245
GeneOntologyMolecularFunction	UDP-glucosyltransferase activity	GYS1 GYS2	1.26e-03	13	82	2	GO:0035251
GeneOntologyMolecularFunction	D-glucose binding	GYS1 GYS2	1.47e-03	14	82	2	GO:0005536
GeneOntologyBiologicalProcess	one-carbon metabolic process	CA13 CA1 CA2 CA7	2.66e-05	44	81	4	GO:0006730
GeneOntologyBiologicalProcess	glycerol-3-phosphate biosynthetic process	GK GK2	4.56e-05	3	81	2	GO:0046167
GeneOntologyBiologicalProcess	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	CACNA1D CACNA2D1 CACNG6	8.51e-05	22	81	3	GO:1902514
GeneOntologyBiologicalProcess	calcium ion transmembrane transport via high voltage-gated calcium channel	CACNA1D CACNA2D1 CACNG6	9.76e-05	23	81	3	GO:0061577
GeneOntologyCellularComponent	calcium channel complex	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	1.19e-05	73	85	5	GO:0034704
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA1D CACNA2D1 CACNG6	1.39e-05	12	85	3	GO:1990454
GeneOntologyCellularComponent	cation channel complex	CACNA1D ATP5MGL ORAI1 CACNA2D1 CACNG6 PKD1	3.95e-04	235	85	6	GO:0034703
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1D CACNA2D1 CACNG6	8.68e-04	46	85	3	GO:0005891
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1D ATP5MGL ORAI1 CACNA2D1 CACNG6 PKD1 SHISA8	8.80e-04	378	85	7	GO:0034702
Domain	DUF1220	NBPF3 NBPF9 NBPF4 NBPF6	4.72e-08	9	84	4	SM01148
Domain	NBPF_dom	NBPF3 NBPF9 NBPF4 NBPF6	1.23e-07	11	84	4	IPR010630
Domain	NBPF	NBPF3 NBPF9 NBPF4 NBPF6	1.23e-07	11	84	4	PS51316
Domain	DUF1220	NBPF3 NBPF9 NBPF4 NBPF6	1.23e-07	11	84	4	PF06758
Domain	Carbonic_anhydrase_a-class_CS	CA13 CA1 CA2 CA7	1.83e-07	12	84	4	IPR018338
Domain	Carbonic_anhydrase_a-class	CA13 CA1 CA2 CA7	5.00e-07	15	84	4	IPR023561
Domain	ALPHA_CA_1	CA13 CA1 CA2 CA7	5.00e-07	15	84	4	PS00162
Domain	ALPHA_CA_2	CA13 CA1 CA2 CA7	8.67e-07	17	84	4	PS51144
Domain	Carb_anhydrase	CA13 CA1 CA2 CA7	8.67e-07	17	84	4	PF00194
Domain	Carb_anhydrase	CA13 CA1 CA2 CA7	8.67e-07	17	84	4	SM01057
Domain	-	CA13 CA1 CA2 CA7	8.67e-07	17	84	4	3.10.200.10
Domain	Carbonic_anhydrase_a	CA13 CA1 CA2 CA7	8.67e-07	17	84	4	IPR001148
Domain	CA2	CA13 CA2	2.00e-05	2	84	2	IPR018443
Domain	Glycogen_synth	GYS1 GYS2	2.00e-05	2	84	2	IPR008631
Domain	Glycogen_syn	GYS1 GYS2	2.00e-05	2	84	2	PF05693
Domain	Carb_kinase_FGGY_CS	GK GK2	5.98e-05	3	84	2	IPR018483
Domain	Glycerol_kin	GK GK2	1.19e-04	4	84	2	IPR005999
Domain	FGGY_KINASES_2	GK GK2	1.98e-04	5	84	2	PS00445
Domain	FGGY_KINASES_1	GK GK2	1.98e-04	5	84	2	PS00933
Domain	Carb_kinase_FGGY_C	GK GK2	1.98e-04	5	84	2	IPR018485
Domain	FGGY_C	GK GK2	2.96e-04	6	84	2	PF02782
Domain	Carb_kinase_FGGY_N	GK GK2	2.96e-04	6	84	2	IPR018484
Domain	Carb_kinase_FGGY	GK GK2	4.14e-04	7	84	2	IPR000577
Domain	FGGY_N	GK GK2	4.14e-04	7	84	2	PF00370
Domain	VWA	CACNA2D1 COL12A1 VWA1	2.05e-03	56	84	3	PF00092
Domain	-	CACNA2D1 COL12A1 VWA1	4.52e-03	74	84	3	3.40.50.410
Pathway	REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	CA13 CA1 CA2 CA7	1.86e-07	12	64	4	M671
Pathway	REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	CA13 CA1 CA2 CA7	1.86e-07	12	64	4	MM14574
Pathway	KEGG_NITROGEN_METABOLISM	CA13 CA1 CA2 CA7	3.21e-06	23	64	4	M4629
Pathway	REACTOME_TRIGLYCERIDE_BIOSYNTHESIS	LPIN3 GK GK2	1.91e-05	12	64	3	MM15447
Pathway	REACTOME_TRIGLYCERIDE_BIOSYNTHESIS	LPIN3 GK GK2	3.13e-05	14	64	3	M619
Pathway	REACTOME_TRIGLYCERIDE_METABOLISM	LPIN3 GK GK2	1.48e-04	23	64	3	MM15575
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1D CACNA2D1 CACNG6	1.91e-04	25	64	3	M47948
Pathway	REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_DVL_INTERACTING_PROTEINS	CCDC88C DVL2	2.01e-04	5	64	2	M27447
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS	GYS1 GYS2	3.01e-04	6	64	2	M47620
Pathway	REACTOME_TRIGLYCERIDE_METABOLISM	LPIN3 GK GK2	6.72e-04	38	64	3	M27856
Pathway	REACTOME_ERYTHROCYTES_TAKE_UP_OXYGEN_AND_RELEASE_CARBON_DIOXIDE	CA1 CA2	7.16e-04	9	64	2	M26928
Pathway	REACTOME_ERYTHROCYTES_TAKE_UP_OXYGEN_AND_RELEASE_CARBON_DIOXIDE	CA1 CA2	7.16e-04	9	64	2	MM14530
Pubmed	Expression of a novel carbonic anhydrase, CA XIII, in normal and neoplastic colorectal mucosa.	CA13 CA1 CA2	1.41e-08	3	85	3	15836783
Pubmed	A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system.	CA13 CA1 CA2 CA7	1.62e-08	12	85	4	17362527
Pubmed	Human carbonic anhydrases and carbonic anhydrase deficiencies.	CA1 CA2 CA7	1.40e-07	5	85	3	7574487
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF3 NBPF9 NBPF4 NBPF6	1.93e-07	21	85	4	16079250
Pubmed	A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development.	CA13 CA1 CA2 CA7	2.35e-07	22	85	4	23233153
Pubmed	Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.	PPP1R3B GYS1 GYS2	4.90e-07	7	85	3	18165236
Pubmed	Carbonic anhydrases in the mouse harderian gland.	CA13 CA2 CA7	7.82e-07	8	85	3	20820888
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LPIN3 CCDC88C ORAI1 ERBB2 TLK1 PPP1R3B INTS1 PKD1 C15orf39 PIP5K1C LYST AHDC1 RNF43	2.78e-06	1105	85	13	35748872
Pubmed	Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury.	NPHS1 DVL2 SYNPO	5.03e-06	14	85	3	25145929
Pubmed	Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures.	CA2 CA7	5.90e-06	2	85	2	23881097
Pubmed	Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design.	CA1 CA2	5.90e-06	2	85	2	16686544
Pubmed	Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV.	CA1 CA2	5.90e-06	2	85	2	17127057
Pubmed	Amelioration of Muc5b mucin hypersecretion is enhanced by IL-33 after 2-APB administration in a murine model of allergic rhinitis.	ORAI1 MUC5B	5.90e-06	2	85	2	24111497
Pubmed	Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis.	PPP1R3B GYS2	5.90e-06	2	85	2	23990365
Pubmed	Autoantibodies Against Carbonic Anhydrase I and II in Patients with Acute Myeloid Leukemia.	CA1 CA2	5.90e-06	2	85	2	28270370
Pubmed	Structural insight into the inhibition of carbonic anhydrase by the COX-2-selective inhibitor polmacoxib (CG100649).	CA1 CA2	5.90e-06	2	85	2	27475498
Pubmed	Inhibition properties of some flavonoids on carbonic anhydrase I and II isoenzymes purified from human erythrocytes.	CA1 CA2	5.90e-06	2	85	2	28445001
Pubmed	Human carbonic anhydrases. XII. The complete primary structure of the C isozyme.	CA1 CA2	5.90e-06	2	85	2	4207120
Pubmed	The Effect of Nanoparticles on the Structure and Enzymatic Activity of Human Carbonic Anhydrase I and II.	CA1 CA2	5.90e-06	2	85	2	32992797
Pubmed	MicroRNA-331-3p inhibits epithelial-mesenchymal transition by targeting ErbB2 and VAV2 through the Rac1/PAK1/β-catenin axis in non-small-cell lung cancer.	ERBB2 VAV2	5.90e-06	2	85	2	30955235
Pubmed	Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.	CA1 CA2	5.90e-06	2	85	2	27526715
Pubmed	Synthesis and in vitro inhibition effect of new pyrido[2,3-d]pyrimidine derivatives on erythrocyte carbonic anhydrase I and II.	CA1 CA2	5.90e-06	2	85	2	25165709
Pubmed	Expression of carbonic anhydrases I/II and the correlation to clinical aspects of oral squamous cell carcinoma analyzed using tissue microarray.	CA1 CA2	5.90e-06	2	85	2	22416960
Pubmed	Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia.	NPHS1 SYNPO	5.90e-06	2	85	2	17255128
Pubmed	Erythrocyte zinc and carbonic anhydrase levels in nondialyzed chronic kidney disease patients.	CA1 CA2	5.90e-06	2	85	2	14675565
Pubmed	Catalytic and inhibitor-binding properties of some active-site mutants of human carbonic anhydrase I.	CA1 CA2	5.90e-06	2	85	2	7758465
Pubmed	Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy.	CA1 CA2	5.90e-06	2	85	2	24670789
Pubmed	Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.	GK GK2	5.90e-06	2	85	2	30662012
Pubmed	Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme.	CA1 CA2	5.90e-06	2	85	2	16807956
Pubmed	Evolution of mammalian carbonic anhydrase loci by tanden duplication: close linkage of Car-1 and Car-2 to the centromere region of chromosome 3 of the mouse.	CA1 CA2	1.77e-05	3	85	2	825106
Pubmed	Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.	CACNA1D CACNA2D1	1.77e-05	3	85	2	11160515
Pubmed	Using evolutionary rates to investigate protein functional divergence and conservation. A case study of the carbonic anhydrases.	CA1 CA2	1.77e-05	3	85	2	12930737
Pubmed	Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility.	GK GK2	1.77e-05	3	85	2	28852571
Pubmed	Mapping of mouse carbonic anhydrase-3, Car-3: another locus in the homologous region of mouse chromosome 3 and human chromosome 8.	CA1 CA2	1.77e-05	3	85	2	2111277
Pubmed	The Daple-CK1ε complex regulates Dvl2 phosphorylation and canonical Wnt signaling.	CCDC88C DVL2	1.77e-05	3	85	2	32888647
Pubmed	Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family.	CA13 CA2	1.77e-05	3	85	2	14600151
Pubmed	Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.	CA1 CA2	1.77e-05	3	85	2	15837325
Pubmed	Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22.	ADAM33 PTPN22	1.77e-05	3	85	2	18923449
Pubmed	Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.	DVL2 RNF43	1.77e-05	3	85	2	32103169
Pubmed	Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8.	CA1 CA2	1.77e-05	3	85	2	1916821
Pubmed	Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors.	CA1 CA2	1.77e-05	3	85	2	19206230
Pubmed	Preservations of nephrin and synaptopodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice.	NPHS1 SYNPO	1.77e-05	3	85	2	21342325
Pubmed	Genes on chromosome 3 of the mouse.	CA1 CA2	1.77e-05	3	85	2	820740
Pubmed	Evaluation of acetylcholinesterase and carbonic anhydrase inhibition profiles of 1,2,3,4,6-pentasubstituted-4-hydroxy-cyclohexanes.	CA1 CA2	1.77e-05	3	85	2	28613396
Pubmed	Unlocking the Potential of the CA2, CA7, and ITM2C Gene Signatures for the Early Detection of Colorectal Cancer: A Comprehensive Analysis of RNA-Seq Data by Utilizing Machine Learning Algorithms.	CA2 CA7	1.77e-05	3	85	2	37895185
Pubmed	An analysis of expression patterns of genes encoding proteins with catalytic activities.	CA13 CA1 CA2 CA7	2.26e-05	67	85	4	17626619
Pubmed	Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.	DVL2 RNF43	3.53e-05	4	85	2	25891077
Pubmed	Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth.	ERBB2 VAV2	3.53e-05	4	85	2	11606575
Pubmed	Carbonic anhydrase enzymes II, VII, IX and XII in colorectal carcinomas.	CA2 CA7	3.53e-05	4	85	2	27688658
Pubmed	Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties.	CA1 CA2	3.53e-05	4	85	2	24878360
Pubmed	Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base.	CA1 CA2	3.53e-05	4	85	2	28544359
Pubmed	Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling.	DVL2 RNF43	3.53e-05	4	85	2	25825523
Pubmed	Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtype.	CACNA1D CACNA2D1	3.53e-05	4	85	2	1309651
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	NPHS1 FLNB CACNA2D1 GK GK2 ARRDC1 PKD1 LTA4H LRRC15 CA2 C16orf89	3.72e-05	1016	85	11	19056867
Pubmed	The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons.	GK GK2	5.87e-05	5	85	2	7987308
Pubmed	Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation.	PKD1 AURKB	5.87e-05	5	85	2	21041232
Pubmed	Novel association of Vav2 and Nek3 modulates signaling through the human prolactin receptor.	NEK3 VAV2	5.87e-05	5	85	2	15618286
Pubmed	Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.	GYS1 GYS2	8.80e-05	6	85	2	14680475
Pubmed	Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ.	PKD1 PIP5K1C	8.80e-05	6	85	2	27775029
Pubmed	The Protein Phosphatase 1 Complex Is a Direct Target of AKT that Links Insulin Signaling to Hepatic Glycogen Deposition.	PPP1R3B GYS2	1.23e-04	7	85	2	31553910
Pubmed	Sjögren's syndrome-like disease of C57BL/6.NOD-Aec1 Aec2 mice: gender differences in keratoconjunctivitis sicca defined by a cross-over in the chromosome 3 Aec1 locus.	CA1 CA2	1.23e-04	7	85	2	16918699
Pubmed	Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects.	GK GK2	1.23e-04	7	85	2	10444329
Pubmed	USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling.	DVL2 RNF43	1.23e-04	7	85	2	33786993
Pubmed	Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.	LYST AURKB	1.64e-04	8	85	2	29946151
Pubmed	Molecular architecture of lineage allocation and tissue organization in early mouse embryo.	NOTO CA2	1.64e-04	8	85	2	31391582
Pubmed	Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family.	SLC22A9 SLC22A24	1.64e-04	8	85	2	17714910
Pubmed	Mice deficient in alpha-actinin-4 have severe glomerular disease.	NPHS1 SYNPO	1.64e-04	8	85	2	12782671
Pubmed	Developmental Renal Glomerular Defects at the Origin of Glomerulocystic Disease.	SYNPO CDH6	2.10e-04	9	85	2	33113370
Pubmed	Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.	NPHS1 SYNPO	2.10e-04	9	85	2	35499085
Pubmed	RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.	DVL2 RNF43	2.10e-04	9	85	2	32965059
Pubmed	Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes.	NPHS1 DVL2	2.10e-04	9	85	2	20534871
Pubmed	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	CA13 CA1 CA2	2.39e-04	49	85	3	23720494
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF9 NBPF6	2.62e-04	10	85	2	22973535
Pubmed	Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure.	NPHS1 SYNPO	2.62e-04	10	85	2	22840396
Pubmed	Role of smooth muscle protein SM22α in glomerular epithelial cell injury.	NPHS1 SYNPO	2.62e-04	10	85	2	21289056
Pubmed	The podocyte protein nephrin is required for cardiac vessel formation.	NPHS1 SYNPO	2.62e-04	10	85	2	21402589
Pubmed	Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.	NPHS1 SYNPO	3.20e-04	11	85	2	11435469
Pubmed	Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription.	FLNB DVL2	3.20e-04	11	85	2	10644691
Pubmed	Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape.	HOXC9 CDH6	3.20e-04	11	85	2	39009564
Pubmed	Expression patterns and subcellular localization of carbonic anhydrases are developmentally regulated during tooth formation.	CA13 CA2	3.20e-04	11	85	2	24789143
Pubmed	Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.	CCDC88C DVL2	3.20e-04	11	85	2	28746879
Pubmed	Nephrin is involved in podocyte maturation but not survival during glomerular development.	NPHS1 SYNPO	3.83e-04	12	85	2	18046313
Pubmed	Wnt-3a is required for somite specification along the anteroposterior axis of the mouse embryo and for regulation of cdx-1 expression.	CDX4 HOXC9	3.83e-04	12	85	2	11335109
Pubmed	Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.	NPHS1 SYNPO	4.52e-04	13	85	2	29114040
Pubmed	Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.	NPHS1 SYNPO	4.52e-04	13	85	2	21406566
Pubmed	A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects.	NPHS1 SYNPO	4.52e-04	13	85	2	26859289
Pubmed	Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.	ERBB2 PKD1	5.27e-04	14	85	2	16400024
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1D CACNA2D1	6.07e-04	15	85	2	20188150
Pubmed	The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.	NPHS1 SYNPO	6.07e-04	15	85	2	28536193
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1D CACNA2D1	6.07e-04	15	85	2	24453333
Pubmed	Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.	NBPF3 PPP1R3B CDH6	6.30e-04	68	85	3	22001757
Pubmed	Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes.	CACNA2D1 DVL2 CDH6	6.57e-04	69	85	3	15142957
Pubmed	Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.	SYNPO CDH6	6.93e-04	16	85	2	17229764
Pubmed	Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies.	EIF2D MAGEC2	6.93e-04	16	85	2	12097419
Pubmed	Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans.	NEK3 TLK1	6.93e-04	16	85	2	8274451
Pubmed	Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling.	CCDC88C DVL2	7.84e-04	17	85	2	32805026
Pubmed	Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.	DVL2 NOTO	7.84e-04	17	85	2	22357932
Pubmed	Expression and functional analysis of genes deregulated in mouse placental overgrowth models: Car2 and Ncam1.	CA1 CA2	8.80e-04	18	85	2	16247769
Pubmed	Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles.	CCDC88C DVL2	8.80e-04	18	85	2	29229865
Pubmed	Loss of endogenous thymosin β4 accelerates glomerular disease.	NPHS1 SYNPO	8.80e-04	18	85	2	27575556
GeneFamily	Carbonic anhydrases	CA13 CA1 CA2 CA7	3.02e-07	18	59	4	460
GeneFamily	Neuroblastoma breakpoint family	NBPF3 NBPF9 NBPF4 NBPF6	8.65e-07	23	59	4	662
GeneFamily	Calcium voltage-gated channel subunits	CACNA1D CACNA2D1 CACNG6	8.14e-05	26	59	3	253
GeneFamily	Glycerol kinases	GK GK2	1.56e-04	6	59	2	568
GeneFamily	Glycosyl transferases group 1 domain containing	GYS1 GYS2	4.63e-04	10	59	2	427
Coexpression	GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP	RALGAPA1 CCDC88C FLNB OTOS ERG CA1 CA2	3.74e-06	200	84	7	M7980
ToppCell	COVID-19_Convalescent\|World / Disease Group and Platelet Clusters	FLNB ERG NBPF9 PRSS23 UBE2E3 CA2	1.15e-06	175	86	6	e9b1faa4c85537f30306619a2f3ada6c8ef0ac6c
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNA1D CACNA2D1 COL12A1 ERG ADAM33 ABCA9	2.04e-06	193	86	6	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	(6)_Stroma\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	COL12A1 RBPMS2 ADAM33 CDH6 ABCA9 C16orf89	2.50e-06	200	86	6	f9baef67dde62f1c161a9408a78f635ea70ea9d3
ToppCell	(6)_Stroma\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	COL12A1 RBPMS2 ADAM33 CDH6 ABCA9 C16orf89	2.50e-06	200	86	6	f0818821c495022569aef2c1886d9f2446dc027e
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	XYLT2 LPIN3 CACNA1D UBE2E3 SHISA8	1.05e-05	149	86	5	68661c8facfb638560bb2e2c20d509941286dacb
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	XYLT2 LPIN3 CACNA1D UBE2E3 SHISA8	1.23e-05	154	86	5	1c62290a2558fd6401b27de5a867d243b143b00a
ToppCell	facs-BAT-Fat-18m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 LTA4H NCR1 BHLHE40 GRAMD4	1.66e-05	164	86	5	ab9c17f86b98e1a4d5db1bd3086edab1320ebda8
ToppCell	Healthy/Control-NK_CD56bright\|World / Disease group and Cell class	FLNB GYS2 NCR1 BHLHE40 RNF43	2.03e-05	171	86	5	79d7efefdae267905af05f3001514b8b6934d86e
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	LPIN3 POU2AF1 SYNPO CA1 CA2	2.33e-05	176	86	5	052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 ERG SYNPO CDH6 C16orf89	2.60e-05	180	86	5	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 ERG SYNPO CDH6 C16orf89	2.60e-05	180	86	5	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 ERG SYNPO CDH6 C16orf89	2.60e-05	180	86	5	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	FLNB RBPMS2 GJC1 CDH6 LRRC15	2.67e-05	181	86	5	35c470988a93381eefa300831aabb813fa1b90bd
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RBPMS2 POU2AF1 SYNPO VAV2 SHISA8	2.74e-05	182	86	5	9c120ddd109103ef6fac9c32b84d16a7624d0580
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL12A1 ERG VWA1 PRSS23 CA2	3.04e-05	186	86	5	a906020a8df6fcca474b278f746c553b177a56b4
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D FLNB CA13 LYST RNF43	3.12e-05	187	86	5	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	ILEUM-inflamed-(1)_Cytotoxic_CD8_Trm\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RALGAPA1 PTPN22 BHLHE40 LYST CA2	3.20e-05	188	86	5	d26894d1066a70e4b32ae41fff1c4718f2591ba9
ToppCell	droplet-Pancreas-Endocrine-21m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPMS2 GJC1 VWA1 PRSS23 C16orf89	3.28e-05	189	86	5	37ce47abd6f96df04d35a4a6189d007bef5ccc94
ToppCell	droplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPMS2 GJC1 VWA1 PRSS23 C16orf89	3.28e-05	189	86	5	b55324cb365a827d071952709bbf0e8ef8c313de
ToppCell	droplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPMS2 GJC1 VWA1 PRSS23 C16orf89	3.28e-05	189	86	5	62e46d59d3b89d4566b595c704d8b02f1ea9060b
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL12A1 ERG GJC1 ADAM33 CDH6	3.36e-05	190	86	5	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	CACNA2D1 COL12A1 GJC1 ADAM33 CDH6	3.45e-05	191	86	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1D COL12A1 ADAM33 PRSS23 ABCA9	3.71e-05	194	86	5	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL12A1 RBPMS2 GJC1 PRSS23 CDH6	3.71e-05	194	86	5	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ERBB2 RBPMS2 PRSS23 NCR1 BHLHE40	3.71e-05	194	86	5	335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ERBB2 RBPMS2 PRSS23 NCR1 BHLHE40	3.90e-05	196	86	5	07b557b8530c19ca5b31ad2eac00c36ef1939266
ToppCell	ILEUM-non-inflamed-(6)_ILC\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP1R3B LTA4H NCR1 BHLHE40 CA2	4.00e-05	197	86	5	76a233eb9611d24b9bb9f4359c26606332a3c29e
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RBPMS2 GJC1 PRSS23 CDH6 CA2	4.00e-05	197	86	5	12370ee857fddf1cf26196b23c21b68dcea48eb3
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL12A1 RBPMS2 GJC1 PRSS23 CDH6	4.00e-05	197	86	5	4a04da876a1482604452ae53c124ae68eda0bd5e
ToppCell	3'-Adult\|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B RNF43 CA1 CA2 CA7	4.09e-05	198	86	5	302adb42089ff22fffc4f01af572ca2e151f7ce7
ToppCell	mild_COVID-19_(asymptomatic)-NK\|World / disease group, cell group and cell class (v2)	CCDC88C PTPN22 PRSS23 NCR1 BHLHE40	4.09e-05	198	86	5	7a0aac52d785037455e068e1b25de4b2bf0fff79
ToppCell	mild_COVID-19_(asymptomatic)-NK\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	ERBB2 PTPN22 PRSS23 NCR1 BHLHE40	4.09e-05	198	86	5	1e43181c13e054570046c7a973ddc1c586e259b0
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RALGAPA1 FLNB ERG CLN6 PRSS23	4.19e-05	199	86	5	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RALGAPA1 FLNB ERG CLN6 PRSS23	4.29e-05	200	86	5	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Lymphoid-NK_cells\|World / shred on cell class and cell subclass (v4)	GK2 PTPN22 NCR1 BHLHE40	1.21e-04	131	86	4	b0b62392d1637601115e85f5584fdcd5dbd0c778
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XYLT2 SYNPO NCR1 RNF43	2.04e-04	150	86	4	a3a4710820a244116a26204f40e7113a1e7236c5
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XYLT2 SYNPO NCR1 RNF43	2.04e-04	150	86	4	13dcd519dacf08d5852aa3e029e0a3308de07321
ToppCell	facs-MAT-Fat-3m-Lymphocytic-NK_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3B PTPN22 NCR1 BHLHE40	2.25e-04	154	86	4	391d40ef902773ffe832a50a14d35d31c56d3723
ToppCell	facs-BAT-Fat-24m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C SNUPN NCR1 UBE2E3	2.31e-04	155	86	4	550e7e7e52829244ead829e5be010bfdc71e2ba5
ToppCell	facs-MAT-Fat-18m-Lymphocytic-NK_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 NCR1 BHLHE40 RNF43	2.43e-04	157	86	4	e6846ffd1bb18bf0469bc6d49ab6cf3533d9cde6
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL12A1 GJC1 ADAM33 CDH6	2.49e-04	158	86	4	8d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL12A1 GJC1 PROB1 CDH6	2.49e-04	158	86	4	84c0a215dabf697ada036c2b9592d0c61b5077de
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-7\|TCGA-Liver / Sample_Type by Project: Shred V9	NEK3 AMER1 RNF43 PRR27	2.55e-04	159	86	4	70288df54adab167c0f50675128619299077db11
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 OTOS PTPN22 NCR1	2.61e-04	160	86	4	398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 OTOS PTPN22 NCR1	2.61e-04	160	86	4	12aaab0291035f578e2433efd169ae72f393a5a5
ToppCell	PND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	XYLT2 NEK3 ABCA9 AURKB	2.61e-04	160	86	4	4480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3\|TCGA-Adrenal / Sample_Type by Project: Shred V9	ERG GJC1 VWA1 CDH6	2.67e-04	161	86	4	52239a887799362256ecd7e740b716b88ed59a62
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3B BMS1 PTPN22 NCR1	2.73e-04	162	86	4	0321fc954ae4ad67ca438cbbc84632562d222188
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3B BMS1 PTPN22 NCR1	2.73e-04	162	86	4	5731f9514434296132df4bc86f78ce87b07cdeca
ToppCell	facs-BAT-Fat-3m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN22 NCR1 BHLHE40 RNF43	2.86e-04	164	86	4	cbdb7e893cb3959b9920c0c7c535ace03a5f4986
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 GJC1 ADAM33 CDH6	2.93e-04	165	86	4	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2R LPO PTPN22 CA2	3.00e-04	166	86	4	9fae71b0a42a9b2222453c03e0a1e83f30117ae9
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ERG LPO CDH6	3.00e-04	166	86	4	01544c851588f1cde05d6700c3d1167f70a0fbd5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ERG LPO CDH6	3.00e-04	166	86	4	c22a97353f7eb084f768c13d7767a80b30f05043
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XKR7 BHLHE40 RNF43 VAV2	3.14e-04	168	86	4	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ERG LPO CDH6	3.21e-04	169	86	4	bddb28a8b9afbe4a68f082e82caf96a6666fc674
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ERG LPO CDH6	3.21e-04	169	86	4	5ce46bac8e767feec7ecdc61689de225c49bd3f7
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCDC88C PTPN22 PRSS23 NCR1	3.21e-04	169	86	4	f06118754fa62c580b4bcbecff6f9e5fdc2106a0
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XRN1 POU2AF1 PTPN22 NCR1	3.21e-04	169	86	4	d721dbb317a88113b4f76688111908d00f23e899
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA1 PRSS23 CA7 C16orf89	3.28e-04	170	86	4	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_RSAD2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ERG LPO CDH6	3.28e-04	170	86	4	63dfbc4746717132dc81b6bac868c7498fc96283
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA1 PRSS23 CA7 C16orf89	3.28e-04	170	86	4	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CACNA1D FLNB CACNG6 BHLHE40	3.28e-04	170	86	4	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA1 PRSS23 CA7 C16orf89	3.28e-04	170	86	4	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NBAS AMER1 PTPN22 NCR1	3.28e-04	170	86	4	65c7ed586e7615203a59999549892ed466a89502
ToppCell	T_cells-GNLY+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ANXA2R RBPMS2 PRSS23 BHLHE40	3.36e-04	171	86	4	04c811817cfec45af5f2891793106cc7ddb0300e
ToppCell	3'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEK3 CA1 CA2 CA7	3.36e-04	171	86	4	317b70d72a4ca5336cfb6a49dc57f8e2a8a1c736
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ERBB2 COL12A1 MUC5B PRSS23	3.43e-04	172	86	4	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16\|GI_small-bowel / Manually curated celltypes from each tissue	RBPMS2 PRSS23 NCR1 LYST	3.43e-04	172	86	4	701de463f85aaad3a4b36a0d5fbc416406620089
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MSANTD1 XKR7 MUC5B C16orf89	3.51e-04	173	86	4	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D PRSS23 ABCA9 CA2	3.51e-04	173	86	4	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 GJC1 ADAM33 CDH6	3.51e-04	173	86	4	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	Healthy/Control-NK_CD56bright\|Healthy/Control / Disease group and Cell class	FLNB GYS2 NCR1 BHLHE40	3.58e-04	174	86	4	f53f675c8cb14294ac526dcc3dca4f08288f8473
ToppCell	LPS-antiTNF-Lymphocytic_B\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OTOS POU2AF1 GRAMD4 SHISA8	3.58e-04	174	86	4	cc493654ea3517bc6a145c7f787f304929636f86
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OTOS POU2AF1 GRAMD4 SHISA8	3.58e-04	174	86	4	9eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OTOS POU2AF1 GRAMD4 SHISA8	3.58e-04	174	86	4	b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XKR7 BHLHE40 RNF43 VAV2	3.66e-04	175	86	4	91cb819a1786020713b7e64480de0545380daae9
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 ERG LPO CDH6	3.66e-04	175	86	4	bc6bd8c3ce956245ef4db91af9501649d5c09478
ToppCell	ASK428-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	ERBB2 CLN6 CA13 POU2AF1	3.66e-04	175	86	4	e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D CA13 VAV2 CA1	3.74e-04	176	86	4	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	XKR7 BHLHE40 RNF43 VAV2	3.82e-04	177	86	4	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	LPS_only-Lymphocytic_B-B_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OTOS POU2AF1 GRAMD4 SHISA8	3.82e-04	177	86	4	c82332c5f656aa26513e4f7525d5d4d733019725
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-NK_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBPMS2 PTPN22 BHLHE40 RNF43	3.82e-04	177	86	4	be35bb178fbc149f8a12984c012d98b486325ba9
ToppCell	LPS_only-Lymphocytic_B\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OTOS POU2AF1 GRAMD4 SHISA8	3.82e-04	177	86	4	5ed65e08d773d157840317c72e0d43c261d438d4
ToppCell	LPS_only-Lymphocytic_B-B_cells-B-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OTOS POU2AF1 GRAMD4 SHISA8	3.82e-04	177	86	4	8a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LPIN3 SYNPO CA7 C16orf89	3.82e-04	177	86	4	d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC88C ERG XRN1 LYST	3.91e-04	178	86	4	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	COVID-19_Mild-NK_CD56bright\|COVID-19_Mild / Disease condition and Cell class	FLNB NCR1 BHLHE40 LYST	3.99e-04	179	86	4	90e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK\|GI_small-bowel / Manually curated celltypes from each tissue	RBPMS2 PRSS23 NCR1 LYST	3.99e-04	179	86	4	535bdfdd990ba9ee3edc8f3ad15297f8fb5a266e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	XYLT2 FLNB COL12A1 PRSS23	3.99e-04	179	86	4	ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA2R PTPN22 NCR1 CA2	4.07e-04	180	86	4	3f0a692ad2823951e0ec23d0452f436c5f5c09c0
ToppCell	mild_COVID-19-NK_CD56bright\|mild_COVID-19 / disease group, cell group and cell class (v2)	LPIN3 FLNB NCR1 BHLHE40	4.07e-04	180	86	4	d8b418edd807a51c0b5f4018b8b478dcc65892a7
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NBPF9 HEPHL1 CA2 CA7	4.07e-04	180	86	4	b234668bf181522807470e396792e1b54890b719
ToppCell	severe-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CACNA1D FLNB CACNG6 BHLHE40	4.07e-04	180	86	4	ac03812b1409435c55d323a7516deeac82bd3509
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC88C PTPN22 NCR1 LYST	4.16e-04	181	86	4	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNG6 ERG SYNPO PRSS23	4.16e-04	181	86	4	0ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAM33 VAV2 LRRC15 SHISA8	4.25e-04	182	86	4	3d7a8d2ee2137b098248597058974ef5ae09c19e
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XRN1 POU2AF1 LYST ABCA9	4.25e-04	182	86	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	RBPMS2 GJC1 ADAM33 CDH6	4.25e-04	182	86	4	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 ADAM33 PRSS23 ABCA9	4.25e-04	182	86	4	44764676ed3f51ba171ce63f669390392fa50a43
Computational	AA biosynthesis.	CA1 CA2 CA7	5.35e-05	18	45	3	MODULE_354
Drug	orthanilamide	CA13 CA1 CA2 CA7	2.70e-09	6	85	4	CID000072894
Drug	Dantrolene-13C3	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1 CA13 CA1 CA2 CA7	3.66e-09	145	85	9	CID000002951
Drug	aminozolamide	CA13 CA1 CA2 CA7	1.25e-08	8	85	4	CID000093505
Drug	L-662,583	CA13 CA1 CA2 CA7	1.25e-08	8	85	4	CID003082977
Drug	L-643,799	CA13 CA1 CA2 CA7	1.25e-08	8	85	4	CID000121595
Drug	sezolamide	CA13 CA1 CA2 CA7	1.25e-08	8	85	4	CID000060692
Drug	qassa	CA13 CA1 CA2 CA7	2.25e-08	9	85	4	CID003082191
Drug	6-hydroxyethoxzolamide	CA13 CA1 CA2 CA7	2.25e-08	9	85	4	CID000094706
Drug	metanilamide	CA13 CA1 CA2 CA7	3.73e-08	10	85	4	CID000007377
Drug	Prontosil	CA13 CA1 CA2 CA7	3.73e-08	10	85	4	CID000066895
Drug	1,3-benzenedisulfonamide	CA13 CA1 CA2 CA7	3.73e-08	10	85	4	CID003090044
Drug	Cl 13850	CA13 CA1 CA2 CA7	5.85e-08	11	85	4	CID000159459
Drug	cobalt phosphate	CA13 CA1 CA2 CA7	5.85e-08	11	85	4	CID000061615
Drug	Tio-urasin	CA13 CA1 CA2 CA7	5.85e-08	11	85	4	CID000084724
Drug	hydroflumethiazide	CA13 CA1 CA2 CA7	8.75e-08	12	85	4	CID000003647
Drug	chlorzolamide	CA13 CA1 CA2 CA7	1.26e-07	13	85	4	CID000165323
Drug	mafenide acetate	CA13 CA1 CA2 CA7	1.26e-07	13	85	4	CID000003998
Drug	Fg 400	CA13 CA1 CA2 CA7	1.26e-07	13	85	4	CID000012443
Drug	mibefradil	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1 GJC1	1.43e-07	64	85	6	CID000060662
Drug	ebrotidine	CACNA2D1 CA13 CA1 CA2 CA7	1.65e-07	34	85	5	CID000065869
Drug	cobalt;sulfide	CA13 CA1 CA2 CA7	1.76e-07	14	85	4	CID000159453
Drug	I-7B	CA13 CA1 CA2	2.00e-07	4	85	3	CID000067136
Drug	chlorthalidone	CACNA2D1 CA13 CA1 CA2 CA7	2.22e-07	36	85	5	CID000002732
Drug	amiloride	CACNA1D ORAI1 CACNA2D1 ERBB2 CACNG6 PKD1 CA13 CA1 CA2 CA7	2.79e-07	315	85	10	CID000016230
Drug	metolazone	CA13 CA1 CA2 CA7	4.15e-07	17	85	4	CID000004170
Drug	apraclonidine	CA13 CA1 CA2 CA7	5.32e-07	18	85	4	CID000002216
Drug	sulthiame	CA13 CA1 CA2 CA7	6.72e-07	19	85	4	CID000005356
Drug	betaxolol	CACNA2D1 CA13 CA1 CA2 CA7	9.72e-07	48	85	5	CID000002369
Drug	EMD 486019	CA1 CA2 CA7	9.96e-07	6	85	3	CID011245700
Drug	2h15	CA1 CA2 CA7	9.96e-07	6	85	3	CID010712038
Drug	AC1LCVB4	CA13 CA1 CA2 CA7	1.03e-06	21	85	4	CID000656627
Drug	AC1NUZ8M	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1 LTA4H	1.25e-06	92	85	6	CID000073211
Drug	AABSSN	CA13 CA1 CA2 CA7	1.26e-06	22	85	4	CID005464134
Drug	tuo	LYST CA1 CA2 CA7	1.52e-06	23	85	4	CID014611919
Drug	dichlorphenamide	CA13 CA1 CA2 CA7	1.52e-06	23	85	4	CID000003038
Drug	indapamide	CACNA2D1 CA13 CA1 CA2 CA7	1.60e-06	53	85	5	CID000003702
Drug	Amlodipine	CACNA1D CACNA2D1 CA1	1.74e-06	7	85	3	DB00381
Drug	potassium cyanate	CA13 CA1 CA2 CA7	1.82e-06	24	85	4	CID011378442
Drug	Cinildipine	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	2.12e-06	56	85	5	CID000002752
Drug	methazolamide	CA13 CA1 CA2 CA7	2.54e-06	26	85	4	CID000004100
Drug	nilvadipine	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	2.99e-06	60	85	5	CID000004494
Drug	benzolamide	CA13 CA1 CA2 CA7	3.46e-06	28	85	4	CID000018794
Drug	lercanidipine	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	3.82e-06	63	85	5	CID000065866
Drug	Zinc chromate hydroxide	CA13 CA1 CA2 CA7	4.00e-06	29	85	4	CID000027567
Drug	thiadiazole	CA13 CA1 CA2 CA7	4.00e-06	29	85	4	CID000067518
Drug	gallopamil	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	5.18e-06	67	85	5	CID000001234
Drug	sulfamide	CA13 CA1 CA2 CA7	5.27e-06	31	85	4	CID000082267
Drug	cetyltrimethylammonium bromide	LPO CA13 CA1 CA2 CA7	5.58e-06	68	85	5	CID000002681
Drug	AC1L2AC7	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	6.00e-06	69	85	5	CID000068733
Drug	dimethadione	CA13 CA1 CA2 CA7	6.01e-06	32	85	4	CID000003081
Drug	benzenesulfonamide	CA13 CA1 CA2 CA7	6.82e-06	33	85	4	CID000007370
Drug	MZ-m	CA13 CA1 CA2 CA7	6.82e-06	33	85	4	CID000001798
Drug	T2755	CACNA2D1 CA13 CA1 CA2 CA7	6.91e-06	71	85	5	CID000005514
Drug	bepridil	CACNA1D ORAI1 CACNA2D1 CACNG6 GYS1 PKD1	7.80e-06	126	85	6	CID000002351
Drug	aspirin	SLC22A9 CACNA2D1 COL12A1 GYS1 GYS2 CA13 ADAM33 LTA4H CA1 CA2 CA7	7.82e-06	563	85	11	CID000002244
Drug	CAS 298-57-7	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	7.92e-06	73	85	5	CID000002761
Drug	STX64	CA1 CA2 CA7	8.11e-06	11	85	3	CID005287541
Drug	ethosuximide	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	8.47e-06	74	85	5	CID000003291
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; HL60; HT_HG-U133A	RALGAPA1 TLK1 GK2 ERG SIGLEC9 SYNPO CA1	9.11e-06	197	85	7	3011_UP
Drug	nisoldipine	CACNA1D ORAI1 CACNA2D1 CACNG6 PKD1	1.10e-05	78	85	5	CID000004499
Drug	bendrofluazide	CA13 CA1 CA2 CA7	1.35e-05	39	85	4	CID000002315
Drug	indisulam	CA13 CA1 CA2 CA7	1.35e-05	39	85	4	CID000216468
Drug	AC1LKFXM	CA1 CA2	1.38e-05	2	85	2	CID000990581
Drug	AC1MDL7D	CA1 CA2	1.38e-05	2	85	2	CID002812911
Drug	Glycoconjugate Benzene Sulfonamide 2f	CA1 CA2	1.38e-05	2	85	2	CID011974631
Drug	CHEBI:492478	CA1 CA2	1.38e-05	2	85	2	CID011974633
Drug	Glycoconjugate Benzene Sulfonamide 2d	CA1 CA2	1.38e-05	2	85	2	CID011974630
Drug	sulfonyl urea 7d	CA1 CA2	1.38e-05	2	85	2	CID011304583
Drug	hydrazide deriv. 16	CA1 CA2	1.38e-05	2	85	2	CID011287480
Drug	NSC-58318	CA1 CA2	1.38e-05	2	85	2	CID000245904
Drug	Glycoconjugate Benzene Sulfonamide 3g	CA1 CA2	1.38e-05	2	85	2	CID011974559
Drug	Glycoconjugate Benzene Sulfonamide 3e	CA1 CA2	1.38e-05	2	85	2	CID011974558
Drug	Glycoconjugate Benzene Sulfonamide 3ff	CA1 CA2	1.38e-05	2	85	2	CID011974562
Drug	Glycoconjugate Benzene Sulfonamide 3dd	CA1 CA2	1.38e-05	2	85	2	CID011974561
Drug	Glycoconjugate Benzene Sulfonamide 3bb	CA1 CA2	1.38e-05	2	85	2	CID011974560
Drug	AC1MM1G7	CA1 CA2	1.38e-05	2	85	2	CID003253857
Drug	urea analog 3a	CA1 CA2	1.38e-05	2	85	2	CID011177131
Drug	disulfide-containing sulfonamide 4	CA1 CA2	1.38e-05	2	85	2	CID016082755
Drug	disulfide-containing sulfonamide 2b	CA1 CA2	1.38e-05	2	85	2	CID016082756
Drug	disulfide-containing sulfonamide 2d	CA1 CA2	1.38e-05	2	85	2	CID016082757
Drug	disulfide-containing sulfonamide 2a	CA1 CA2	1.38e-05	2	85	2	CID016082752
Drug	disulfide-containing sulfonamide 2c	CA1 CA2	1.38e-05	2	85	2	CID016082753
Drug	disulfide-containing sulfonamide 3	CA1 CA2	1.38e-05	2	85	2	CID016082754
Drug	Glycoconjugate Benzene Sulfonamide 3d	CA1 CA2	1.38e-05	2	85	2	CID011974456
Drug	Glycoconjugate Benzene Sulfonamide 3b	CA1 CA2	1.38e-05	2	85	2	CID011974455
Drug	Glycoconjugate Benzene Sulfonamide 2dd	CA1 CA2	1.38e-05	2	85	2	CID011974452
Drug	Glycoconjugate Benzene Sulfonamide 2bb	CA1 CA2	1.38e-05	2	85	2	CID011974451
Drug	Glycoconjugate Benzene Sulfonamide 2gg	CA1 CA2	1.38e-05	2	85	2	CID011974454
Drug	Glycoconjugate Benzene Sulfonamide 2ff	CA1 CA2	1.38e-05	2	85	2	CID011974453
Drug	Glycoconjugate Benzene Sulfonamide 3ee	CA1 CA2	1.38e-05	2	85	2	CID011974830
Drug	Glycoconjugate Benzene Sulfonamide 3gg	CA1 CA2	1.38e-05	2	85	2	CID011974831
Drug	sulfonyl urea 4d	CA1 CA2	1.38e-05	2	85	2	CID011339017
Drug	DIBA-1	CA1 CA2	1.38e-05	2	85	2	CID000375084
Drug	M2-9	CA1 CA2	1.38e-05	2	85	2	CID016122582
Drug	Glycoconjugate Benzene Sulfonamide 2ee	CA1 CA2	1.38e-05	2	85	2	CID011974727
Drug	CHEBI:492482	CA1 CA2	1.38e-05	2	85	2	CID011974729
Drug	Glycoconjugate Benzene Sulfonamide 3f	CA1 CA2	1.38e-05	2	85	2	CID011974724
Drug	CHEBI:492477	CA1 CA2	1.38e-05	2	85	2	CID011974726
Drug	azide 1	CA1 CA2	1.38e-05	2	85	2	CID003558590
Drug	DNC006493	CA1 CA2	1.38e-05	2	85	2	CID011640067
Disease	carbonic anhydrase 13 measurement	CA13 CA1	7.63e-06	2	82	2	EFO_0008067
Disease	glycerol kinase deficiency (implicated_via_orthology)	GK GK2	2.28e-05	3	82	2	DOID:0060363 (implicated_via_orthology)
Disease	carbonic anhydrase 1 measurement	CA13 CA1	2.28e-05	3	82	2	EFO_0020227
Disease	Lafora disease (implicated_via_orthology)	GYS1 GYS2	4.56e-05	4	82	2	DOID:3534 (implicated_via_orthology)
Disease	Hereditary Diffuse Gastric Cancer	NBAS ERBB2 RNF43 CA1 CA2 AURKB	1.69e-04	293	82	6	C1708349
Disease	Stomach Neoplasms	NBAS ERBB2 RNF43 CA1 CA2 AURKB	1.82e-04	297	82	6	C0038356
Disease	Malignant neoplasm of stomach	NBAS ERBB2 RNF43 CA1 CA2 AURKB	1.92e-04	300	82	6	C0024623
Disease	estrogen measurement	SLC22A9 SLC22A24	3.38e-04	10	82	2	EFO_0011007
Disease	polycystic kidney disease (implicated_via_orthology)	XYLT2 PKD1	6.79e-04	14	82	2	DOID:0080322 (implicated_via_orthology)
Disease	Sinus Node Dysfunction (disorder)	CACNA1D CACNA2D1	7.82e-04	15	82	2	C0428908
Disease	Muscle hypotonia	RALGAPA1 INTS1	1.01e-03	17	82	2	C0026827
Disease	dilated cardiomyopathy (implicated_via_orthology)	ORAI1 ERBB2 MTCH2	1.46e-03	80	82	3	DOID:12930 (implicated_via_orthology)
Disease	hematocrit	RALGAPA1 CACNA2D1 ERG GYS2 SYNPO UBE2E3 RNF43 VAV2 AURKB	1.96e-03	1011	82	9	EFO_0004348
Disease	alkaline phosphatase measurement	NBPF3 RALGAPA1 TLK1 SIGLEC9 PPP1R3B PKD1 PTPN22 BHLHE40 UBE2E3	2.02e-03	1015	82	9	EFO_0004533
Disease	Intrahepatic Cholangiocarcinoma	ERBB2 RNF43	2.02e-03	24	82	2	C0345905
Disease	stomach carcinoma (is_marker_for)	ERBB2 RNF43	2.02e-03	24	82	2	DOID:5517 (is_marker_for)
Disease	Extrahepatic Cholangiocarcinoma	ERBB2 RNF43	2.02e-03	24	82	2	C3805278
Disease	Cholangiocarcinoma	ERBB2 RNF43	2.37e-03	26	82	2	C0206698
Disease	Glycogen Storage Disease	GYS1 GYS2	2.56e-03	27	82	2	C0017919

Protein segments in the cluster

Peptide	Gene	Start	Entry
ITGYLYISAWPDSLP	ERBB2	406	P04626
YSPPREDWSVYPGPS	CDX4	76	O14627
LPSSWDYRSVPPYLA	C16orf89	351	Q6UX73
PTVYTLWSYPDLLPT	EIF2D	81	P41214
SYPWELSPNTYFLSP	ABCA9	891	Q8IUA7
KCWYPTSVPVLYPGL	BHLHE40	341	O14503
PYWNSPTGGIYPNTR	ERG	451	P11308
PSYYEPWGYTPAECT	GYS2	506	P54840
YDTPYIIWRSLPTDP	GRAMD4	386	Q6IC98
LSLYTEPPGAYDWPA	AMER1	946	Q5JTC6
TLSRNASYYLRPWPP	ADAM33	141	Q9BZ11
LPPSWDYWTYPGSLT	CA13	186	Q8N1Q1
DYWTYPGSLTVPPLL	CA13	191	Q8N1Q1
YWYPPGSAARSPPYE	AHDC1	1466	Q5TGY3
WPLPLYPVLGEYSLD	ANXA2R	36	Q3ZCQ2
WYPVSIPAFYNPVTS	BMS1	1101	Q14692
EPPPAPRLTYEYSWS	CACNG6	206	Q9BXT2
GATPWPLLPTFSYQY	DVL2	541	O14641
LPPEYSSWGYPYEAP	ARRDC1	401	Q8N5I2
WYYTTVELVPPTPAE	ATP5MGL	31	Q7Z4Y8
SEWLDYSYPMPGPSG	MUC5B	2321	Q9HC84
LAGGCPPYSPIYTSW	MTCH2	251	Q9Y6C9
LPDLTPSYHPYWSTL	NBPF4	371	Q96M43
SPEAWAPYPLYTTEL	RBPMS2	151	Q6ZRY4
LVENPYFSSWPPSGT	PTPN22	531	Q9Y2R2
PYVWGQYDLLVLPPS	LTA4H	251	P09960
NIQWESRTYPYPGTP	FBXO42	101	Q6P3S6
ESAPPDWPYYLAIDG	MSANTD1	116	Q6ZTZ1
RTYPPSGAWGPLYDE	NPHS1	1181	O60500
YPYSDGEWPPQASLS	LPIN3	201	Q9BQK8
WAPVPSQSSVVYHPY	HOXC9	66	P31274
HSSPPYYEFLWGPRA	MAGEC2	291	Q9UBF1
PEDPTFPADTWGTYL	NCR1	221	O76036
VPAFSGLYAPYWEPS	GK3P	361	Q14409
PGYQPPNLAISTLYW	INTS1	721	Q8N201
SPEPGGDPQTVWYEY	CCDC88C	2011	Q9P219
PPSAVTYPDWIGQSY	ORAI1	46	Q96D31
YPSTPGRYSIAITWG	FLNB	516	O75369
WIPPYQGYSESVDPR	LPO	441	P22079
TSWLPAYLSVGFYPV	NOTO	96	A8MTQ0
YIWYSPAPFLLPDGL	NBAS	66	A2RRP1
TYVGTPYYVPPEIWE	NEK3	161	P51956
PWILTSPGFPYVYHI	PRR27	76	Q6MZM9
PWTPYTEYVPHEAVS	POU2AF1	101	Q16633
LDRWYSTPFSYPELP	NBPF3	496	Q9H094
YAELPAMPYWPFSTS	OTOS	31	Q8NHW6
VPAFSGLYAPYWEPS	GK2	361	Q14410
WDPSPSPVLGYKIVY	COL12A1	2136	Q99715
ATGLARYYPASPWVD	CACNA2D1	211	P54289
DFWTYPGSLTHPPLY	CA1	191	P00915
DPGAYNYPFTWNTPS	GJC1	271	P36383
FVPAFSGLYAPYWEP	GK	366	P32189
SGLYAPYWEPSARGI	GK	371	P32189
IYYPTSWQLDPTEGP	LYST	2941	Q99698
PSDPNCIPWVYYSTV	HEPHL1	876	Q6MZM0
FWVGQPYPTLSTPLS	CDH6	11	P55285
RHYWTYPGSLTTPPL	CA7	191	P43166
WTVYPPLAGNYSHPG	MT-CO1	126	P00395
PSYYEPWGYTPAECT	GYS1	506	P13807
ATPPYRDWTPCYTPL	CACNA1D	1986	Q01668
PPFPYRYTWDFGTEE	PKD1	1406	P98161
SPRCSYGLFPEWPSY	PPP1R3B	261	Q86XI6
AYSPHLPWISYGVFP	SLC22A24	491	Q8N4F4
ETPWYPDTPSYPDTT	LRRC15	486	Q8TF66
LPDLTPSYHPYWSTL	NBPF6	371	Q5VWK0
LGRWYSTPSGYLELP	NBPF9	711	P0DPF3
SWVRSPPSYSVLYPS	SYNPO	576	Q8N3V7
SVYSPPLPWIIYGVF	SLC22A9	491	Q8IVM8
SWVYSPLHYSAQAPP	PIP5K1C	646	O60331
VSPYSAPWKPTWPAY	PRSS23	21	O95084
FPHYTPSVAYPWSPE	RNF43	681	Q68DV7
CSFSYPSHGWIYPGP	SIGLEC9	41	Q9Y336
YAPPAAPGPYAAWTS	SHISA8	316	B8ZZ34
YSPGSTPLVGWLRPY	SNUPN	266	O95149
LPWVSEAGPLDGTYY	PROB1	966	E7EW31
RGLLPESLDYWTYPG	CA2	181	P00918
PGVIYVPEPWAFYTL	CLN6	291	Q9NWW5
EQLASWTPYPPLYST	C15orf39	61	Q6ZRI6
NSYPWPYGRQTAPSG	AURKB	6	Q96GD4
AWPPLLTADSGYYVL	VWA1	231	Q6PCB0
LTSQGAGTYWYLPPE	TLK1	626	Q9UKI8
PAAAETADPLFYPSW	TRIM55	431	Q9BYV6
WFVYDYSEPAGSPGP	XKR7	111	Q5GH72
YSWDSAILYGPPPVS	RALGAPA1	1606	Q6GYQ0
YEWRSTILGPPGSVY	UBE2E3	91	Q969T4
PPPTGWDHYGSNYAL	XRN1	1536	Q8IZH2
EGWSPSPPLYEEYRP	SMIM44	11	A0A286YF18
PPSREIDYTAYPWFA	VAV2	661	P52735
PARYPIPFSSADYWS	ZFC3H1	1821	O60293
YPPGTPALKAYWENT	XYLT2	526	Q9H1B5