Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 MYD88 MYH10 MYH11 ATP6V1G2 KIF15 TOR1A CHD7 MSH3 ATP6V1C2 DDX11L8 DDX11

3.80e-066147712GO:0140657
GeneOntologyMolecularFunctionsmall GTPase binding

BICD2 KNTC1 IQGAP2 GIT1 DAAM2 IQGAP3 RPH3A GOLGA4

3.28e-05321778GO:0031267
GeneOntologyMolecularFunctionGTPase binding

BICD2 KNTC1 IQGAP2 GIT1 DAAM2 IQGAP3 RPH3A GOLGA4

7.36e-05360778GO:0051020
GeneOntologyMolecularFunctiontriplex DNA binding

DDX11L8 DDX11

8.76e-054772GO:0045142
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

MYD88 CHD7 MSH3 DDX11L8 DDX11

1.32e-04127775GO:0008094
GeneOntologyMolecularFunctiondynein light intermediate chain binding

BICD2 DNHD1 CCDC88C

1.69e-0428773GO:0051959
GeneOntologyMolecularFunction5'-3' DNA helicase activity

DDX11L8 DDX11

7.89e-0411772GO:0043139
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly

IQGAP2 IQGAP3

4.12e-053772GO:1903475
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP3

4.12e-053772GO:1903479
GeneOntologyBiologicalProcessassembly of actomyosin apparatus involved in mitotic cytokinesis

IQGAP2 IQGAP3

4.12e-053772GO:1902407
GeneOntologyBiologicalProcessactomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP3

8.21e-054772GO:2000689
GeneOntologyCellularComponentmicrotubule organizing center

BICD2 CCDC88C MAPK15 KIF15 GIT1 USP9X POLR3H ITSN2 PKD2 LRRCC1 JADE1 DDX11L8 DDX11

2.12e-059197513GO:0005815
GeneOntologyCellularComponentcentrosome

BICD2 CCDC88C KIF15 GIT1 USP9X POLR3H ITSN2 LRRCC1 JADE1 DDX11L8 DDX11

9.00e-057707511GO:0005813
GeneOntologyCellularComponentspindle

KNTC1 MYH10 MAPK15 KIF15 GIT1 PKD2 DDX11L8 DDX11

2.82e-04471758GO:0005819
GeneOntologyCellularComponentCtf18 RFC-like complex

DDX11L8 DDX11

5.61e-0410752GO:0031390
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase, V1 domain

ATP6V1G2 ATP6V1C2

8.19e-0412752GO:0000221
GeneOntologyCellularComponentproton-transporting V-type ATPase, V1 domain

ATP6V1G2 ATP6V1C2

8.19e-0412752GO:0033180
GeneOntologyCellularComponentspindle pole

KNTC1 KIF15 GIT1 DDX11L8 DDX11

8.55e-04205755GO:0000922
GeneOntologyCellularComponentmyosin complex

MYH10 MYH11 CGNL1

1.25e-0359753GO:0016459
GeneOntologyCellularComponentlamellipodium

MYH10 IQGAP2 GIT1 PTPRO PKD2

1.43e-03230755GO:0030027
DomainRasGAP_C

IQGAP2 IQGAP3

4.63e-053742IPR000593
DomainRasGAP_C

IQGAP2 IQGAP3

4.63e-053742PF03836
DomainMyosin_tail_1

MYH10 MYH11 CGNL1

4.67e-0518743PF01576
DomainMyosin_tail

MYH10 MYH11 CGNL1

4.67e-0518743IPR002928
DomainMyosin_S1_N

MYH10 MYH11

1.54e-045742IPR008989
DomainIQ

MYH10 MYH11 IQGAP2 IQGAP3

1.80e-0471744PF00612
DomainIQ

MYH10 MYH11 IQGAP2 IQGAP3

3.00e-0481744SM00015
DomainIQ_motif_EF-hand-BS

MYH10 MYH11 IQGAP2 IQGAP3

4.48e-0490744IPR000048
DomainIQ

MYH10 MYH11 IQGAP2 IQGAP3

5.08e-0493744PS50096
DomainRasGAP

IQGAP2 IQGAP3

1.37e-0314742SM00323
DomainRasGAP_CS

IQGAP2 IQGAP3

1.37e-0314742IPR023152
DomainRasGAP

IQGAP2 IQGAP3

1.57e-0315742PF00616
DomainRAS_GTPASE_ACTIV_1

IQGAP2 IQGAP3

1.57e-0315742PS00509
DomainMyosin_N

MYH10 MYH11

1.57e-0315742PF02736
DomainRAS_GTPASE_ACTIV_2

IQGAP2 IQGAP3

1.57e-0315742PS50018
DomainMyosin_N

MYH10 MYH11

1.57e-0315742IPR004009
Domain-

IQGAP2 IQGAP3

1.79e-03167421.10.506.10
DomainRasGAP_dom

IQGAP2 IQGAP3

2.27e-0318742IPR001936
DomainMyosin-like_IQ_dom

MYH10 MYH11

2.54e-0319742IPR027401
Domain-

MYH10 MYH11

2.54e-03197424.10.270.10
DomainFilament

LMNB1 KRT32 SYNC

2.81e-0371743SM01391
DomainIF

LMNB1 KRT32 SYNC

2.93e-0372743PS00226
DomainFilament

LMNB1 KRT32 SYNC

3.04e-0373743PF00038
DomainIF

LMNB1 KRT32 SYNC

3.41e-0376743IPR001664
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

WDR91 KNTC1 MYH10 MYH11 LMNB1 IQGAP2 GIT1 USP9X ITSN2 RNF20 MTR IQGAP3

3.51e-057205912M41838
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

KNTC1 MYH10 MYH11 LMNB1 IQGAP2 GIT1 USP9X ITSN2 RNF20 MTR IQGAP3

6.72e-056495911MM15690
PathwayREACTOME_RHO_GTPASE_CYCLE

WDR91 LMNB1 IQGAP2 GIT1 USP9X ITSN2 RNF20 MTR IQGAP3

9.67e-05450599M27078
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BICD2 KNTC1 KIF15 GIT1 RBBP7 USP9X MTR RIOK3 CHD7 CGNL1 GAB1 DDX11

7.68e-09588781238580884
Pubmed

The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2.

LMNB1 IQGAP2 GIT1 IQGAP3

6.99e-081878419961560
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

WDR91 CCDC88C MYH10 KIF15 LMNB1 IQGAP2 GIT1 USP9X CHD7 CABIN1 RPH3A GOLGA4 LRRFIP2

2.17e-07963781328671696
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

BICD2 PIK3AP1 WDR3 CCDC88C MYH10 LMNB1 GIT1 PRIM1 PDCL3 ITSN2 LRRCC1 CGNL1

4.32e-07853781228718761
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

WDR3 DNHD1 KNTC1 MYH10 MAPK15 LMNB1 USP9X PRIM1 RNF20 MTR MSH3 IQGAP3 GOLGA4 LRRFIP2

3.10e-061425781430948266
Pubmed

Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.

IQGAP2 IQGAP3

4.97e-06278229073199
Pubmed

Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.

MYH10 MYH11

4.97e-06278216316347
Pubmed

Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue.

MYH10 MYH11

4.97e-06278210906735
Pubmed

Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.

MYH10 MYH11

4.97e-0627827916668
Pubmed

Expression profile of immune-associated genes in nasal polyps.

IL17B IL17RA

4.97e-06278216805377
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

PIK3AP1 CCDC88C ITSN2 RNF20 SYNC

5.30e-0611178522558309
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

BICD2 WDR3 STX1A GIT1 USP9X LRRCC1 DAAM2 TFIP11 SYNC MSH3 PDCD7 CABIN1 RPH3A

5.32e-061285781335914814
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PIK3AP1 PHLDB3 KNTC1 FAM193A MTR TFIP11 CHD7 CWC25 SLC26A6 GOLGA4

5.63e-06733781034672954
Pubmed

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11.

MYH11 CHD7

1.49e-05378229018080
Pubmed

IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils.

MYD88 IL17RA

1.49e-05378222577359
Pubmed

The biology of IQGAP proteins: beyond the cytoskeleton.

IQGAP2 IQGAP3

1.49e-05378225722290
Pubmed

IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.

IQGAP2 IQGAP3

1.49e-05378222493426
Pubmed

Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

DDX11L8 DDX11

1.49e-05378217611414
Pubmed

Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin.

MYH10 MYH11

1.49e-05378216973711
Pubmed

Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.

IQGAP2 IQGAP3

1.49e-05378225229330
Pubmed

Mammalian ChlR1 has a role in heterochromatin organization.

DDX11L8 DDX11

1.49e-05378221854770
Pubmed

Early MyD88-dependent induction of interleukin-17A expression during Salmonella colitis.

MYD88 IL17RA

1.49e-05378221576324
Pubmed

Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins.

MYD88 LRRFIP2

2.97e-05478219265123
Pubmed

Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.

IQGAP2 IQGAP3

2.97e-05478228970065
Pubmed

Modification of the inflammatory mediator LRRFIP2 by the ubiquitin-like protein FAT10 inhibits its activity during cellular response to LPS.

MYD88 LRRFIP2

2.97e-05478223036196
Pubmed

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

BICD2 MYH11 RNF20 MSH3

4.13e-058578419596235
Pubmed

Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle.

STX1A RPH3A

4.94e-05578210099709
Pubmed

Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt.

PIK3AP1 MYD88

4.94e-05578222187460
Pubmed

Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosis.

ATP6V1G2 ATP6V1C2

4.94e-05578212384298
Pubmed

Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation.

LMNB1 TOR1A

4.94e-0557828324822
Pubmed

Telokin expression is restricted to smooth muscle tissues during mouse development.

MYH10 MYH11

4.94e-05578211121372
Pubmed

Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope.

LMNB1 TOR1A

7.40e-05678216364897
Pubmed

IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain.

IQGAP2 IQGAP3

7.40e-05678221299499
Pubmed

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.

MYD88 IL17RA

7.40e-05678221993848
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYH10 MYH11 ATP6V1G2 IQGAP2 GIT1 RBBP7 USP9X ITSN2 LRRCC1 CGNL1 RPH3A LRRFIP2

7.91e-051431781237142655
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KNTC1 MYH10 MYH11 TM9SF4 IQGAP3

9.41e-0520278533005030
Pubmed

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome Overview

MYH11 PDCL3

1.04e-04778231070878
Pubmed

IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment.

MYD88 IL17RA

1.04e-04778235081371
Pubmed

EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?

STX1A ITSN2

1.04e-04778210373452
Pubmed

TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection.

MYD88 IL17RA

1.04e-04778221402950
Pubmed

Noncanonical imprinting sustains embryonic development and restrains placental overgrowth.

JADE1 GAB1

1.04e-04778235483741
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KNTC1 CCDC88C MYH11 TBC1D12 LRRCC1 CGNL1 ANO8

1.22e-0449378715368895
Pubmed

The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis.

DDX11L8 DDX11

1.38e-04878222678773
Pubmed

Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction.

MYH10 MYH11

1.38e-04878233424621
Pubmed

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.

MYD88 IL17RA

1.38e-04878220364087
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

MYH10 RBBP7 PRIM1 PDCL3 RNF20 TFIP11 LRRFIP2

1.43e-0450678730890647
Pubmed

Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice.

MYD88 CAPSL

1.77e-04978216300676
Pubmed

Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome.

PIK3AP1 MYD88

1.77e-04978227909057
Pubmed

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota.

MYD88 IL17RA

1.77e-04978231542340
Pubmed

Lipocalin 2 is required for pulmonary host defense against Klebsiella infection.

MYD88 IL17RA

1.77e-04978219342674
Pubmed

Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0.

MYH10 GIT1 USP9X LRRFIP2

1.79e-0412478435516420
Pubmed

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.

DAAM2 GOLGA4 DDX11

2.62e-045578318570454
Pubmed

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.

MYD88 IL17RA

2.70e-041178223034650
Pubmed

Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits.

ATP6V1G2 ATP6V1C2

2.70e-041178212527205
Pubmed

TLR9-independent CD8+ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.

MYD88 F8

3.23e-041278238053332
Pubmed

IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.

IQGAP2 IQGAP3

3.23e-041278218604197
Pubmed

Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.

MYH10 MYH11

3.23e-04127828424456
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

MYH10 MYH11 KRT32 USP9X GAB1

3.38e-0426678519380743
Pubmed

Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development.

MYH11 CHD7

3.81e-041378223319608
Pubmed

Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles.

IL17B IL17RA

3.81e-041378230824326
Pubmed

Sequence and expression of murine type I hair keratins mHa2 and mHa3.

KIF15 KRT32

4.44e-04147827514534
Pubmed

IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis.

MYD88 IL17RA

4.44e-041478223853597
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MYH10 MYH11 ATP6V1G2 LMNB1 KRT32 RNF20 DAAM2 IQGAP3

4.55e-0480778830575818
Pubmed

A molecular mechanism underlying the neural-specific defect in torsinA mutant mice.

LMNB1 TOR1A

5.12e-041578220457914
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

MYH10 LMNB1 IQGAP2 RBBP7 ITSN2 CHD7 LRRFIP2

5.18e-0462678733644029
Pubmed

The DNA sequence of human chromosome 22.

HSCB POLR3H TFIP11 IL17RA CABIN1

5.83e-0430078510591208
Pubmed

Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.

STX1A RPH3A

5.84e-041678212590134
Pubmed

In vivo dual-tagging proteomic approach in studying signaling pathways in immune response.

MYD88 LRRFIP2

6.61e-041778215952741
Pubmed

ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells.

MYH10 CGNL1 LRRFIP2

6.78e-047678336380368
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

IQGAP2 RBBP7 USP9X MTR TFIP11

7.06e-0431378538270169
Pubmed

A human MAP kinase interactome.

MYH10 MYH11 ZBTB8OS ITSN2 CGNL1 GAB1

7.93e-0448678620936779
Pubmed

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.

BICD2 MYH10

8.28e-041978216105984
Pubmed

Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.

HK3 KRT32

8.28e-041978212543931
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

WDR3 PHLDB3 MYH10 LMNB1 RNF20 RIOK3 TFIP11 CHD7 MSH3 GOLGA4

8.74e-041353781029467282
Pubmed

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.

BICD2 RBBP7 RNF20 VPS28 LRRFIP2

9.18e-0433278529053956
Pubmed

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.

ATP6V1G2 ATP6V1C2

9.19e-042078222982048
Pubmed

An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

KNTC1 MYH10 GIT1 GAB1

9.52e-0419378420677014
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

WDR3 MYH10 MYH11 LMNB1 IQGAP2 TFIP11 CHD7 PDCD7 CWC25 LRRFIP2

9.66e-041371781036244648
Pubmed

Huntingtin interacting proteins are genetic modifiers of neurodegeneration.

WDR91 STX1A USP9X RNF20

1.03e-0319778417500595
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

MYH10 USP9X TFIP11 CHD7

1.03e-0319778420811636
Pubmed

Myosin-X recruits lamellipodin to filopodia tips.

USP9X IL17RA GOLGA4

1.07e-038978336861887
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

MYH10 STX1A LMNB1 RBBP7 USP9X TFIP11 VPS28 IQGAP3

1.08e-0392278827609421
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

BICD2 KNTC1 LMNB1 PDCL3 ITSN2 TFIP11 VPS28 IQGAP3 LRRFIP2

1.11e-03115578920360068
Pubmed

The vacuolar (H+)-ATPases--nature's most versatile proton pumps.

ATP6V1G2 ATP6V1C2

1.11e-032278211836511
Pubmed

Proton translocation driven by ATP hydrolysis in V-ATPases.

ATP6V1G2 ATP6V1C2

1.11e-032278212788495
Pubmed

Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.

ATP6V1G2 ATP6V1C2

1.11e-032278214580332
Pubmed

Neurotransmitter release: the dark side of the vacuolar-H+ATPase.

ATP6V1G2 ATP6V1C2

1.11e-032278214597263
Pubmed

Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.

ATP6V1G2 ATP6V1C2

1.11e-032278217662945
Pubmed

A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.

PIK3AP1 MYD88

1.22e-032378222761313
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

MMRN1 MYH10 RNF20 MSH3 GOLGA4

1.31e-0336078533111431
Pubmed

Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression.

MYH10 MYH11

1.44e-032578220019329
Pubmed

Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.

ATP6V1G2 ATP6V1C2

1.44e-03257822874839
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

MYH10 LMNB1 RBBP7 MSH3

1.52e-0321978431353912
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

STX1A RPH3A

1.56e-032678217124501
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

PIK3AP1 GIT1 GAB1

1.63e-0310378321706016
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

PIK3AP1 F8

1.68e-032778226544073
Pubmed

Same but different - Molecular comparison of human KTI12 and PSTK.

MTR GOLGA4

1.68e-032778233417976
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

KNTC1 MYH10 ATP6V1G2 PRIM1 IQGAP3 GOLGA4

1.70e-0356478621565611
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

HSCB WDR3 FAM193A LMNB1 MTR TOR1A EEF2K TFIP11 GOLGA4 GAB1

1.77e-031487781033957083
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

WDR3 LMNB1 IQGAP2 EEF2K CGNL1 GOLGA4 GAB1

1.81e-0377778735844135
InteractionSYCE1 interactions

BICD2 CCDC88C FAM193A RNF20 TFIP11 GOLGA4

9.15e-06127776int:SYCE1
InteractionOBI1 interactions

HSCB KNTC1 MYD88 FAM193A SYNC GOLGA4

1.53e-05139776int:OBI1
CytobandEnsembl 112 genes in cytogenetic band chr3p22

MYD88 GOLGA4 LRRFIP2 KRBOX1

2.83e-04184784chr3p22
GeneFamilyMyosin heavy chains

MYH10 MYH11

5.43e-04154221098
GeneFamilyDNA helicases

CHD7 DDX11

7.01e-04174221167
GeneFamilyV-type ATPases

ATP6V1G2 ATP6V1C2

1.29e-0323422415
CoexpressionGSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP

MYD88 CCDC88C LMNB1 RIOK3 CHD7 IL17RA PLTP

2.27e-06200787M7020
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

KNTC1 MYH10 KIF15 IQGAP2 USP9X ITSN2 RNF20 MTR MSH3 GOLGA4

2.45e-056567810M18979
CoexpressionGSE3982_MAST_CELL_VS_TH1_DN

KNTC1 MYH10 HK3 LMNB1 TM9SF4 CMAHP

2.82e-05198786M5454
CoexpressionGSE14026_TH1_VS_TH17_UP

HK3 PTPRO KRT32 IL17B CHD7 PDCD7

2.98e-05200786M3356
CoexpressionYAGI_AML_WITH_INV_16_TRANSLOCATION

MYH11 KRT32 USP9X TM9SF4 ITSN2 PKD2 TOR1A GAB1

3.07e-05411788M1047
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP

KNTC1 STX1A POLR3H PRIM1 CHD7 MSH3 IQGAP3 DDX11L8 ANO8 DDX11

3.32e-056807810MM456
CoexpressionAtlasB cells, proB.FrBC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-1

MMRN1 PIK3AP1 PHLDB3 KNTC1 KIF15 LMNB1 PRIM1 CAPSL EEF2K

8.68e-06376779GSM538418_500
CoexpressionAtlasB cells, preB.FrD.FL, AA4.1+ IgM- CD19+ CD43- CD24+, Fetal Liver, avg-3

MMRN1 PIK3AP1 PHLDB3 KNTC1 KIF15 LMNB1 PRIM1 CAPSL EEF2K

1.29e-05395779GSM538340_500
CoexpressionAtlasB cells, proB.FrBC.BM, CD19+ IgM- CD43+ AA4.1+ CD45R+, Bone marrow, avg-2

MMRN1 PIK3AP1 PHLDB3 KNTC1 KIF15 LMNB1 PRIM1 CAPSL EEF2K

1.45e-05401779GSM399450_500
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 KIF15 IL17B LRRCC1 IQGAP3 DDX11

4.58e-0716578696f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 MYH11 JADE1 CGNL1 CMAHP GOLGA4

1.05e-06190786d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KNTC1 KIF15 LMNB1 PRIM1 IQGAP3 DDX11

1.05e-06190786d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KNTC1 MYH11 KIF15 LMNB1 PRIM1 DDX11

1.15e-06193786bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIK3AP1 HK3 LMNB1 CHD7 IL17RA

8.34e-061577855098675f64342c41c5ca3551b24962d10c83e64d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYD88 KIF15 PDCL3 IL17B IQGAP3

9.15e-06160785830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

9.43e-061617850dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

9.43e-06161785b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

9.43e-06161785efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

9.43e-0616178528d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

1.00e-051637855285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

1.06e-0516578588681101d7cf60b99b8ace5d8c0944323b937306
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

1.19e-05169785e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 MAPK15 KIF15 SYNC IQGAP3

1.30e-0517278535c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAPK15 IL17B CAPSL KIAA2012 ACOX2

1.33e-05173785a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCellwk_20-22-Hematologic-Myeloid-Promonocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HK3 KIF15 LMNB1 IL17RA IQGAP3

1.41e-05175785654299df246debe0a5b12f0d9568eb828bb94bb9
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KNTC1 CCDC88C LMNB1 IQGAP2 PRIM1

1.45e-051767859e719e6323597ecfc758c957256872cd4ae24d4d
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HK3 LMNB1 PRIM1 MTR IQGAP3

1.57e-051797859dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMRN1 KNTC1 IQGAP2 PRIM1 DDX11

1.57e-05179785df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCellASK454-Endothelial-Lymphatic|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

MMRN1 MYH10 FAM193A PRIM1 RNF20

1.57e-05179785fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

1.62e-05180785334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCelldroplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 CAPSL ATP6V1C2 KIAA2012 ACOX2

1.75e-051837853991830726d05cf19606d540de04093985b7bdeb
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 CAPSL ATP6V1C2 KIAA2012 ACOX2

1.75e-05183785cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

MYH10 RBBP7 CHD7 JADE1 PDCD7

1.84e-05185785857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

2.04e-051897851e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 KIF15 LMNB1 PRIM1 IQGAP3

2.15e-0519178515dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 KIF15 LMNB1 PRIM1 IQGAP3

2.15e-0519178545c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

PIK3AP1 IQGAP2 DAAM2 IL17RA PLTP

2.20e-051927857be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 MYH11 KIF15 JADE1 IQGAP3

2.26e-05193785a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

2.26e-051937854b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KNTC1 KIF15 LMNB1 PRIM1 DDX11

2.37e-05195785cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KNTC1 KIF15 LMNB1 PRIM1 DDX11

2.37e-05195785b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

HK3 PTPRO PKD2 RPH3A PLTP

2.37e-051957856800c17026ec6c56132bf4664b8fcd74d7836579
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KNTC1 KIF15 LMNB1 PRIM1 DDX11

2.37e-0519578556d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF15 LMNB1 PRIM1 IQGAP3 DDX11

2.43e-051967859591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KNTC1 KIF15 LMNB1 PRIM1 DDX11

2.43e-05196785df366d76ea55f49e349d622effa57c1535df8400
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KNTC1 KIF15 LMNB1 PRIM1 IQGAP3

2.49e-051977850a6754a5109bec0d0de42adbfdf4db43ff60c3d2
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

2.61e-0519978598575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

2.61e-05199785be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

2.68e-052007854cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

KNTC1 KIF15 LMNB1 IQGAP3 DDX11

2.68e-052007859bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KNTC1 KIF15 LMNB1 PRIM1 IQGAP3

2.68e-052007851b65c97e8123d0572d31525d6a10bc7f16857959
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 KIF15 TIGD5 IQGAP3

7.81e-05129784739b263296c28554967362060b154f7a95e1341d
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 KIF15 TIGD5 IQGAP3

8.04e-05130784615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF15 DAAM2 TIGD5 IQGAP3

8.53e-0513278402491930097b75aaeedab9e8200711b0dc610944
ToppCellVE-CD8-memory_CD4|VE / Condition, Cell_class and T cell subcluster

CCDC88C ATP6V1C2 SAMD3 KIAA2012

1.47e-041527849401b7770c1bdc87eba25e82922f5dd1c4fa37ee
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|368C / Donor, Lineage, Cell class and subclass (all cells)

PIK3AP1 ZBTB8OS HK3 CAPSL

1.51e-04153784e0fbbfd4d13031412e0b985322c8b99c56eb7af5
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IQGAP2 PRIM1 GGACT SAMD3

1.62e-0415678433deda19f06172079ef1dd49fd54d66da1e7fb14
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KNTC1 CAPSL ATP6V1C2 SAMD3

1.62e-041567842cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 KNTC1 KIF15 TIGD5

1.67e-041577840fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88C MTR ATP6V1C2 JADE1

1.71e-04158784debebc8534a80e5500051f6fd352dc201585968d
ToppCellSevere-Lymphoid-NK-|Severe / Condition, Lineage, Cell class and cell subclass

CHD7 CGNL1 SAMD3 PDCD7

1.79e-04160784d276c6cb8317d5fb19e7b4fe5238abaf0272d4c6
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88C KIF15 SAMD3 DDX11

1.92e-04163784a763c1632d6465a1e753bdc8eadaf819d2b09e5e
ToppCell3'_v3-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

KNTC1 KIF15 IQGAP3 ACOX2

1.92e-0416378447300dec94dc66e965bf71fafff0a9fd24fae968
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

1.92e-041637843f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88C KIF15 SAMD3 DDX11

1.92e-04163784eaed783eecd07aafa5af844b63c9d816b4da99e4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 IL17B DAAM2 SAMD3

1.97e-0416478443630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 IL17B DAAM2 SAMD3

1.97e-04164784108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH11 IL17B DAAM2 SAMD3

1.97e-0416478446208f18325976c89f572f6627aea0582142b92d
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KNTC1 ZBTB8OS KIF15 CMAHP

2.06e-04166784a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH11 TFIP11 ACOX2 ANO8

2.06e-0416678494a00edf66d54bc5f7343daea700ca26cf38fd90
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 LMNB1 IQGAP2 PRIM1

2.11e-04167784d21635df8b74189e3309eaf435af381fbe412574
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HK3 EEF2K KIAA2012 IQGAP3

2.16e-041687840e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HK3 EEF2K KIAA2012 IQGAP3

2.16e-0416878434722e14f28313f2e4644b3c1861ef12958cee9f
ToppCellfacs-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88C IQGAP2 PTPRO IL17RA

2.21e-0416978405b138511039f1255a5f647040b1b9bdf222bd52
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.21e-041697840bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC88C GVINP1 IQGAP2 SAMD3

2.21e-04169784f06118754fa62c580b4bcbecff6f9e5fdc2106a0
ToppCellfacs-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88C IQGAP2 PTPRO IL17RA

2.21e-04169784bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRCC1 GGACT CGNL1 MYRF

2.21e-04169784aec97583b23112060437b619cb429dc32f29285f
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 LMNB1 IQGAP2 PRIM1

2.26e-04170784b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 HEBP2 CGNL1 MYRF

2.31e-041717845447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

STX1A LMNB1 PTPRO DDX11

2.31e-04171784e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC88C GVINP1 IQGAP2 SAMD3

2.31e-04171784e1fe07652c10c37191d1471ddaea500f74269e0c
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

STX1A LMNB1 PTPRO DDX11

2.31e-0417178452fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 PHLDB3 ZBTB8OS F8

2.36e-04172784b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 IQGAP2 PRIM1 SAMD3

2.36e-041727844bdcf1ae2a1cfba0272c54072e37fb7958904321
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 HEBP2 CGNL1 MYRF

2.36e-04172784a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN1 PHLDB3 ZBTB8OS F8

2.36e-041727842f1673fcb2356684d60871debb0f159aec553a1c
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 HEBP2 CGNL1 MYRF

2.36e-041727840a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF15 LMNB1 PRIM1 SAMD3

2.41e-04173784c399786aa25bdbe3394988db6955842b5b7e6b41
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

HK3 KIF15 IQGAP3 ACOX2

2.41e-04173784783b8fa08b9d8f597f251793eae164151662f1f9
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TSR2 STX1A RNF20 F8

2.41e-041737847e2149205e119cec4f5099c83c85d1e13470137a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.47e-0417478484da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.47e-041747847b318796728001c17b4043d2b033330c7be40c78
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.47e-04174784dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 KIF15 LMNB1 IQGAP3

2.47e-041747847b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYH10 MYH11 PKD2 DAAM2

2.52e-041757841799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 LMNB1 IQGAP2 SAMD3

2.52e-04175784ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.52e-04175784876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 PTPRO RNF20 MTR

2.58e-041767846b4afd2c9268172063fe5832896bea15e862579e
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 STX1A LMNB1 DAAM2

2.58e-04176784feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCellCF-Lymphoid-pDC|CF / Disease state, Lineage and Cell class

MMRN1 MTR EEF2K GAB1

2.58e-04176784dd1e529a9e413bcaab43584afbe059e1464ffb53
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH11 KIF15 LMNB1 IQGAP3

2.58e-0417678445c6983ab671b0f306e7390320bd84f848e474cc
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|367C / Donor, Lineage, Cell class and subclass (all cells)

KIF15 LMNB1 PRIM1 IQGAP3

2.63e-04177784ba701d3c90722d8bff70d0fa651899305cdad257
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

WDR91 PRIM1 TIGD5 SLC26A6

2.75e-0417978468511e87b12b8253de7771e5ccfc5869248b8450
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIF15 PRIM1 IQGAP3 DDX11

2.75e-04179784ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.75e-0417978488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.75e-0417978480112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

STX1A MYH11 IL17B IL17RA

2.75e-0417978483506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 KIF15 LMNB1 IQGAP3

2.81e-04180784401df9cddcbca1eb8f0d2687bcacd98e95dc1493
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX11L8 DDX11

1.91e-053752DOID:0060535 (implicated_via_orthology)
DiseaseAqueductal Stenosis

CCDC88C MYH10

1.77e-048752C2936786
DiseaseLymphoma, Large-Cell, Follicular

MYD88 MTR

6.55e-0415752C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

MYD88 MTR

6.55e-0415752C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

MYD88 MTR

6.55e-0415752C0079758
DiseaseLymphoma, Follicular, Grade 2

MYD88 MTR

6.55e-0415752C1956132
DiseaseLymphoma, Follicular, Grade 3

MYD88 MTR

6.55e-0415752C1956131
DiseaseLymphoma, Follicular, Grade 1

MYD88 MTR

6.55e-0415752C1956130
Diseasefree cholesterol to total lipids in large LDL percentage

STX1A MYRF PLTP

8.98e-0474753EFO_0022280
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

MYRF PLTP

1.06e-0319752EFO_0004612, EFO_0008589
DiseaseLymphoma, Follicular

MYD88 MTR

1.18e-0320752C0024301
Diseasereaction time measurement

BICD2 IQGAP2 PTPRO ITSN2 MSH3 SAMD3 RPH3A

1.42e-03658757EFO_0008393
Diseasecolorectal carcinoma (is_implicated_in)

MYD88 MSH3

1.42e-0322752DOID:0080199 (is_implicated_in)
Diseasemean corpuscular hemoglobin concentration

HSCB KNTC1 MYD88 IQGAP2 PRIM1 RNF20 CMAHP KIAA2012 MYRF

1.92e-031105759EFO_0004528
DiseaseHypermetropia

CCDC88C PTPRO CHD7

2.32e-03103753HP_0000540

Protein segments in the cluster

PeptideGeneStartEntry
QMEVEQYRREREHEF

ATP6V1G2

41

O95670
VEEALRHRQEYDEMV

TBC1D12

411

O60347
MAQEEEDVRDYNLTE

ZBTB8OS

1

Q8IWT0
DIESERYMQSFDVER

ACOX2

21

Q99424
AQVRKEYEMLRIEFE

RNF20

446

Q5VTR2
EYEMLRIEFEQTLAA

RNF20

451

Q5VTR2
FEELEVDYEAIRSEM

BICD2

61

Q8TD16
EERAREEMQRYAEDV

CWC25

46

Q9NXE8
REAELRQAMDIPEEY

GVINP1

126

Q7Z2Y8
FEELAMDVYDEVDRR

GIT1

276

Q9Y2X7
MDVYDEVDRRENDAV

GIT1

281

Q9Y2X7
EQYVELEERMEYVRA

DNHD1

841

Q96M86
DLRQFIDEYVETVDM

PIK3AP1

386

Q6ZUJ8
YVEVDRIMDFARSTD

CHD7

881

Q9P2D1
VDMDETEREVEYFKR

FAM193A

1221

P78312
VAEEMAKLEYQRREA

ANO8

871

Q9HCE9
EERYMADLQLVVEVF

ITSN2

1221

Q9NZM3
EMREQLDVAQRAYED

PHLDB3

221

Q6NSJ2
YAFDEEETEMRNQVV

DAAM2

116

Q86T65
DRIRVERMDNIYFEY

MSH3

451

P20585
MDRFEEVYFRIQDLE

IL17RA

526

Q96F46
EQLRSKLEEMYEERE

KIF15

1306

Q9NS87
YARMEEYERNIEEMV

IL17B

56

Q9UHF5
AKRYEEILDAREEEM

GOLGA4

2056

Q13439
DALERRINEYALEME

MMRN1

711

Q13201
RAENDRDIYLVFEFM

MAPK15

81

Q8TD08
DRIFYLVADSEEEMN

GAB1

91

Q13480
DVFIEDRAEMTVFVR

HEBP2

126

Q9Y5Z4
QYEAMVEANRRDVEE

KRT32

271

Q14532
EFRKSMYEEEINETR

LMNB1

206

P20700
DVDFYKARMEELRED

CCDC88C

341

Q9P219
YEAEERALRVMLEGE

PDCD7

366

Q8N8D1
QLQEEERMVYVAFSE

PLTP

256

P55058
DEFNEEDERAIEMYR

PDCL3

61

Q9H2J4
MAEEERLEYQRRKQE

KIAA2012

1121

Q0VF49
AEEMDFEYLEIRQLE

MYD88

51

Q99836
IRVYMREHDLQEEEL

KNTC1

741

P50748
EVYAVDERMLRFLDD

GGACT

66

Q9BVM4
YIRAEVEDNIMVTFR

F8

1781

P00451
SIQEDFMAELYRVLE

DDX11

21

Q96FC9
YMEEARHVAVLDEDR

HK3

251

P52790
AAYERLTAEEMDEQR

IQGAP3

11

Q86VI3
VIEEQEEQMAEFYRE

LRRFIP2

406

Q9Y608
MFEDTVEERVINEEY

RBBP7

6

Q16576
EREENFTEYLMVDEE

PTPRO

366

Q16827
LVFDIDMTDYDDVRR

PRIM1

106

P49642
AQREDLETAMEFYLE

CABIN1

101

Q9Y6J0
YAVVMEKEEVEELFR

CAPSL

71

Q8WWF8
LMEEELRDYQRAQDE

CGNL1

1016

Q0VF96
SIQEDFMAELYRVLE

DDX11L8

21

A8MPP1
RDVMLENYEAVAFVV

KRBOX1

41

C9JBD0
VDRDVYFEDVRLQME

EEF2K

176

O00418
MFILEQEEYQREGIE

MYH10

491

P35580
ERTDYEMDRQFLIEI

HSCB

151

Q8IWL3
EVQQYREQLEEMEER

SYNC

406

Q9H7C4
LFYERMDTIDQDDEL

USP9X

1951

Q93008
YYDEKEIEREREEMA

ATP6V1C2

251

Q8NEY4
AVRYEIDNDLMEFNI

TRIM42

346

Q8IWZ5
ARGMALYEEEQVERV

RPH3A

531

Q9Y2J0
LVMQTEAARDYRDEE

SAMD3

81

Q8N6K7
NIFHDFREIEVEVYM

SLC26A6

691

Q9BXS9
EEMDERRRQNIAYEY

IQGAP2

26

Q13576
FEEIMEEYEDIRQDH

MTR

906

Q99707
YMDTGEEIRFRVVDE

POLR3H

141

Q9Y535
LDEYTMERVLEEFEQ

JADE1

166

Q6IE81
YNLVVRMIETDEDFN

CMAHP

366

Q9Y471
MFILEQEEYQREGIE

MYH11

491

P35749
LQAETELYAEAEEMR

MYH11

896

P35749
MEYDREYDAQLRREE

RIOK3

86

O14730
EDYFMRNADLELDEV

TSR2

51

Q969E8
IRVEMQSRGYEIDED

TOR1A

281

O14656
REDMEEDQEHTYRVV

TM9SF4

191

Q92544
RDRFMDEFFEQVEEI

STX1A

26

Q16623
REREKYDNMAELFAV

VPS28

31

Q9UK41
YEEFQVLVRRVDRME

PKD2

836

Q13563
AAERIMEAIELYREE

WDR3

756

Q9UNX4
MRLANEEEIDRAVYA

TIGD5

116

Q53EQ6
MAEAVERTDELVREY

WDR91

1

A4D1P6
KDFQYEAMQERREAE

TFIP11

741

Q9UBB9
YMDLENEFRIALTVE

LRRCC1

636

Q9C099
MEVVDETEALQRFFE

MYRF

1

Q9Y2G1